CN108524305A - A kind of child skin barrier repairs moisturiser and preparation method thereof - Google Patents

A kind of child skin barrier repairs moisturiser and preparation method thereof Download PDF

Info

Publication number
CN108524305A
CN108524305A CN201810566057.6A CN201810566057A CN108524305A CN 108524305 A CN108524305 A CN 108524305A CN 201810566057 A CN201810566057 A CN 201810566057A CN 108524305 A CN108524305 A CN 108524305A
Authority
CN
China
Prior art keywords
moisturiser
skin
homogeneous
children
stirring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201810566057.6A
Other languages
Chinese (zh)
Other versions
CN108524305B (en
Inventor
杨森
张学军
张博
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yang Sen
Zhang Bo
Zhang Xuejun
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201810566057.6A priority Critical patent/CN108524305B/en
Publication of CN108524305A publication Critical patent/CN108524305A/en
Application granted granted Critical
Publication of CN108524305B publication Critical patent/CN108524305B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to technical field of skin care, and in particular to a kind of child skin barrier repairs the preparation method of moisturiser and its optimization, which includes the ingredients such as moisturizing emollients, anti-sensitizer, antioxidant, antistatic agent.Moisturiser provided by the invention can effectively make up to a certain extent had a single function existing for the moisturiser that the prior art is provided, the limited defect of water lock moisture-keeping functions, the effective skin-nourishing that improves is provided to be metabolized, make tender smooth, the elastic increase of skin, it avoids using irritating acid-base modifier and the organic solvent being more toxic, it is allowed to mild, moist, it can utmostly ensure the moisturizing to baby child's skin and repair, reach the ideal effect of nutrient absorption.

Description

A kind of child skin barrier repairs moisturiser and preparation method thereof
Technical field
The invention belongs to technical field of skin care, and in particular to a kind of child skin barrier repairs moisturiser and its preparation side Method.
Background technology
Face cream refers to the white shape cosmetics for playing skin care effect for face or body.It is coated in the face cream meeting of face Thin film is formed on the skin, prevents skin water loss.Moisturizing refers to the moisturizing of skin, can moisten cuticula, skin Seem microgroove, fine wrinkles desalination after skin is full.Children's moisturiser on the market is varied, but the effect is unsatisfactory.
Oat is grown in the extremely frigid zones of 1000-2700 meters of height above sea level as a kind of ancient cereal crops, has high protein The characteristics of low-carb, is widely used in food and healthcare products field.Protein water imbibition is strong in oat, Ke Yibang It helps and maintains skin moisture, structure skin sparing barrier prevents water loss, and skin surface faintly acid pH can be maintained to balance, had Effect soothes the skin the discomforts such as redness, itch, and oat grain class formation can adsorb dead skin, therefore is widely used in making up In product product.
It since the skin children of infant is tender, has a low resistance, and is easy by mechanicalness to the irritation from external environment Damage, easy infection skin disease, therefore, the no added natural skin care product of safety are the new trends of children's skincare product development.
Baby child's skin is weaker, be susceptible to dry peeling, skin it is red itch, FAQs, the baby child such as fragile sensitivity it is special Mild nonirritant moisturiser product have increasing demand;But usually irritation is larger for existing baby child's moisturiser, Moistening effect is poor, and containing drawbacks such as irritant larger acid-base modifier, the organic solvents being more toxic, is unfavorable for baby child The healthy growth of skin, or have a single function, cannot effectively reach water lock moisture-keeping functions;Therefore, market urgently research safety, protect Wet effect is good, moistens degree by force without greasy children's moisturiser product.
Invention content
The technical problem to be solved in the present invention is to provide a kind of shield to child skin it is mild nonirritant Baby child's skin repair moisturiser can effectively improve skin-nourishing metabolism, avoid using the larger acid-base modifier of irritation, poison The larger organic solvent etc. of property.
Technical solution of the present invention is as follows
The present invention provides a kind of children's moisturiser, which is characterized in that the component of children's moisturiser includes a kind of or more Kind of moisturizer, oiliness moisturizing agent, surface agent, emollients, anti-sensitizer, emulsifier, acid-base modifier, antioxidant, antistatic agent, Preservative, lubricant and solvent.
In a preferred scheme of the invention, the moisturizer is selected from glycerine, glycerine, ceramide, saualane, three Methylglycine (NMF-50), plants essential oil, panthenol, isomery hexadecane hydrocarbon (HD), one kind in peony root extractive (PRE) or A variety of, the oiliness moisturizing agent is one or more in vaseline or vaseline, and the surface agent is selected from cetanol, palm One or more in alcohol, C16-18 fatty alcohols, it is sweet that the emollients are selected from cetanol, palmityl alcohol, stearic acid, caprylic/capric It is one or more in oily three esters, olive oil, one kind in oat, beta glucan, dipotassium glycyrrhizinate of the anti-sensitizer or A variety of, the emulsifier is selected from polysorbate60, sapn (Span 60), stearine (MS165), stearic acid, isomery hexadecane One or more in hydrocarbon (HD), the acid-base modifier is one or more in triethylamine, and the antioxidant is selected from It is one or more in allantoin, vitamin E, sodium citrate or sodium citrate, the one kind of the antistatic agent in oat Or it is a variety of, the preservative is selected from one kind in methyl p-hydroxybenzoate, propylparaben (PP/MP), fragrant fresh ketone Or it is a variety of, the lubricant selected from dimethicone, silicon spirit or ground Mei Sikang in it is one or more, the solvent be selected from water, It is one or more in glycerine, glycerine, butanediol, mineral oil, atoleine;The preferred Roman chamomile flower of vegetable oil Oil.
In a preferred scheme of the invention, the component of children's moisturiser contains following weight percent:
In a preferred scheme of the invention, component contains following weight percent:
In a preferred scheme of the invention, the component contains following weight percent:
The present invention also provides a kind of preparation methods of children's moisturiser, which is characterized in that the method includes
(1) component mixing, the stirring in A phases are warming up to 80 DEG C, stirring, homogeneous are for use;
(2) component mixing, the stirring in B1 phases are warming up to 90 DEG C, stirring, homogeneous are for use;
(3) B phases and B1 mixed, stir and be warming up to 90 DEG C, stir, homogeneous it is for use;
(4) A phases are continued into stirring, homogeneous under stirring, vacuumized conditions, it is for use after cooling;
C is added to the homogeneous object obtained by step (4) at (5) 70 DEG C, continues homogeneous, D phases are added after the completion, continue to stir It mixes uniformly;
E is added in the homogeneous object obtained by step (5) at (6) 45 DEG C and is stirred evenly;
(7) to plate, filtering and discharging, standing are to be checked after the assay was approved.
Advantageous effect of the invention:
It is compared with the prior art, of the invention to achieve following progress,
1, children's moisturiser of the present invention avoids the organic solvent being more toxic using benzaldehyde etc.;
2, children's moisturiser of the present invention is avoided using the larger acid-base modifier of the alkalinity such as sodium hydroxide and irritation;
3, children's moisturiser of the present invention is full of nutrition, can repair skin simultaneously with tender skin, moisturizing, increase elasticity, grow Moisten skin and promotes skin vis medicatrix naturae and metabolism;
4, the component raw material of children's moisturiser of the present invention is easy to get, irritation is small, preparation process is simple, easy to operate, is conducive to work Sparetime university produces.
Specific implementation mode
The present invention is further elaborated with reference to embodiment.These embodiments be only for illustrative purposes, And do not limit the scope of the invention and essence.
The preparation of embodiment 1, children's moisturiser
A kind of children's moisturiser is made of following parts by weight raw material:
The preparation method of children's moisturiser includes:
1, the preparation before sample:(1) utensil/apparatus and equipment cleaning-sterilizing are weighed needed for confirming before weighing, with This time the unrelated all items of production have cleared scene;(2) confirm that equipment disinfection meets hygienic requirements, production scene symbol before preparing Conjunction hygienic requirements, raw material confirm errorless.
2, steps are as follows for specific sample:
(1) A is added to oil cauldron stirring and is warming up to 80 DEG C;
(2) component mixing, the stirring in B1 phases are warming up to 90 DEG C, stirring, homogeneous are for use;
(3) B phases and B1 are added to emulsification pot stirring and are warming up to 90 DEG C, stir frequency conversion 30, homogeneous 1 minute, homogeneous frequency conversion 45;
(4) A phases are pumped into emulsification pot by (stirring frequency conversion 30) under stirring, and are evacuated to -0.05MP homogeneous 8 minutes, equal qualitative change Frequently 45, heat preservation cools down after twenty minutes;
C is added to the homogeneous object obtained by step (4) at (5) 70 DEG C, vacuumizes homogeneous 3 minutes, homogeneous frequency conversion 45, D phases are added after the completion of matter to stir evenly.
E is added in the homogeneous object obtained by step (5) at (6) 45 DEG C and is stirred evenly, frequency conversion 30 is stirred;
(7) to plate, filtering and discharging, standing are to be checked after the assay was approved.
The preparation of embodiment 2, children's moisturiser
A kind of children's moisturiser is made of following parts by weight raw material:
Method of the children's moisturiser during the preparation method is the same as that of Example 1.
Embodiment 3, determination of moisture
Using Aveeno oats frost as the reference examples of the present invention skin is used after comparing two kinds of moisturisers smearing hand 30min The moisture that tester is measured is as a result as follows:
Embodiment 4, cutaneous safety test
Using 20 male and female childrens more than one full year of life of not skin disease as object, allow them to above-mentioned Aveeno oats frost It is evaluated with the stimulation degree of each solvent made in children's moisturiser obtained by the embodiment of the present invention, evaluation result is such as Under.It applies on front side of the arm of experimenter after spreading the sample of 20 μ L, behind on Test sites enclosed hood 24 hours, cover is taken The reaction on skin after opening 30 minutes and after 24 hours, is checked according to the technical term on CTFA guides.According to judgement The score of benchmark, the experimenter of acquisition averagely gets off, and evaluation result is low stimulation degree less than 1, is slightly to pierce if being discontented with 3 Swash degree, be moderate stimulation degree if discontented 5, is intense stimulus degree if 5 or more.
Experiment conclusion:It can determine whether by upper table data, Aveeno oats frost is entirely skin irritatin with embodiment 1, embodiment 2 As a result it less than 1, therefore can be assumed that, the present invention is the low irritation level that can be applied in product.
Embodiment 5, film forming moisture-keeping efficacy experiment
36 equal this experiments of voluntary participation of volunteer.
The barrier function for reflecting cuticula through transepidermal water loss value (TEWL) is the important finger for evaluating cutin layer state Mark.Protective layer of skin is more intact, and the numerical value of TEWL is lower.Use skin water loss tester (Tewameter TM300 the water vapor pressure gradient near epidermis) is measured, numerical value, curve and the average value and standard deviation of TEWL can be obtained Etc. data, cosmetics moisture-keeping efficacy is evaluated.
Volunteer (36, man:18;Female:18) experiment before half an hour enter laboratory, sit quietly 30 minutes time.With Left arm smears the embodiment of the present invention 1 and prepares obtained children's moisturiser as test zone;The corresponding symmetrical region of right arm is not Any skin care item are smeared, as blank control.Each test is detected with skin water loss tester (Tewameter TM300) The skin water loss amount in region, different time detects after smearing, repeats detection 3 times every time.By each time point detection The average value that average value subtracts blank control is the measured value i.e. TEWL value addeds at period position, and each time point is examined The average value of survey divided by the average value of blank control are the TEWL change rates at period position.
TEWL testing results are as shown in the table:
After children's moisturiser of embodiment 1, TEWL values have the tendency that reduction, show the guarantor of children's moisturiser of the present invention Wet function is good, film forming is stablized.The result for children's moisturiser that embodiment 2 obtains is with the above results without significant difference.
Embodiment 6, usability function test
Please each 30 of evaluation group member men and women (total 60), actually use each embodiment product, reference substance, press respectively Slickness, delicacy, sticky sense etc. are evaluated according to following evaluation criteria.
(1) evaluation criteria of skin slickness
◎:30 or 30 or more syndics feel that skin is smooth
○:10-29 syndics feel that skin is smooth
△:5-9 syndics feel that skin is smooth
×:4 or 4 syndics below feel that skin is smooth
(2) evaluation criteria of skin delicacy
◎:30 or 30 or more syndics feel skin delicacy
○:10~29 syndics feel skin delicacy
△:5-9 syndics feel skin delicacy
×:4 or 4 syndics below feel skin delicacy
(3) evaluation criteria of the sticky sense of skin
◎:30 or 30 or more the imperceptible skin of syndic are sticky
○:10~29 imperceptible skin of syndic are sticky
△:The 5-9 imperceptible skin of syndic are sticky
×:The 4 or 4 imperceptible skin of syndic below are sticky
(4) emulsibility
The emulsibility of embodiment, each sample of reference substance is evaluated according to following standards.
○:During emulsification forms water-in-oil type (w/o type) emulsion, can equably it be emulsified
△:During emulsification forms water-in-oil type (w/o type) emulsion, it can be seen that part water floating material and oil float Float (emulsification is bad)
×:It cannot emulsify to form water-in-oil type (w/o type) emulsion
(5) stability
Respectively to preserving 30 with embodiment product, reference substance under 0 DEG C, room temperature (25 DEG C), 37 DEG C, 50 DEG C of temperature part It, according to following standard rating stability.
○:It can't see separation completely
△:It can be seen that separation
×:It can be seen that apparent separation
Evaluation result is as shown in the table:
Compare classification Embodiment 1 Embodiment 2 Aveeno oat frosts
Slickness
Skin is delicate
The sticky sense of skin
Emulsibility
0℃
Room temperature (25 DEG C)
37℃
50℃ ×
Experiment conclusion:As seen from the above table, (slickness, skin are delicate or clear for the embodiment of the present invention 1 and the usability of 2 products Moisture feeling, sticky sense) it is suitable with Aveeno oat frosts, but (37 DEG C, 50 DEG C) of emulsibility and stability are better than Aveeno oat frosts.

Claims (6)

1. a kind of child skin barrier repairs moisturiser, which is characterized in that the component of children's moisturiser includes a kind of or more Kind of moisturizer, oiliness moisturizing agent, surface agent, emollients, anti-sensitizer, emulsifier, acid-base modifier, antioxidant, antistatic agent, Preservative, lubricant and solvent.
2. child skin barrier as described in claim 1 repairs moisturiser, which is characterized in that the moisturizer be selected from glycerine, Hyaluronic acid, oat concentrate, glycerine, ceramide, saualane, trimethylglycine NMF-50, plants essential oil, panthenol, One or more in isomery hexadecane hydrocarbon HD, peony root extractive PRE, the oiliness moisturizing agent is in vaseline or vaseline It is one or more, the surface agent is one or more in cetanol, palmityl alcohol, C16-18 fatty alcohols, described soft and moist Agent is one or more in cetanol, palmityl alcohol, stearic acid, caprylic/capric triglyceride, olive oil, the anti-sensitizer One or more in oat, beta glucan, dipotassium glycyrrhizinate, the emulsifier is selected from polysorbate60, sapn Span60, sweet One or more in oleostearin acid esters MS165, stearic acid, isomery hexadecane hydrocarbon HD, the acid-base modifier is selected from triethylamine In one or more, the one kind or more of the antioxidant in allantoin, vitamin E, sodium citrate or sodium citrate Kind, the antistatic agent is one or more in oat, and the preservative is selected from methyl p-hydroxybenzoate, para hydroxybenzene One or more in propyl formate PP/MP, fragrant fresh ketone, the lubricant is in dimethicone, silicon spirit or ground Mei Sikang It is one or more, the solvent is one or more in water, glycerine, glycerine, butanediol, mineral oil, atoleine; The preferred Roman chamomile caul-fat of plants essential oil.
3. such as claim 1-2 any one of them children's moisturisers, which is characterized in that the component contains following weight percent:
4. children's moisturiser as claimed in claim 3, which is characterized in that the component contains following weight percent:
5. children's moisturiser as claimed in claim 4, which is characterized in that the component contains following weight percent:
6. the preparation method of children's moisturiser as described in claim any one of 3-5, which is characterized in that the method includes
(1) component mixing, the stirring in A phases are warming up to 80 DEG C, stirring, homogeneous are for use;
(2) component mixing, the stirring in B1 phases are warming up to 90 DEG C, stirring, homogeneous are for use;
(3) B phases and B1 mixed, stir and be warming up to 90 DEG C, stir, homogeneous it is for use;
(4) A phases are continued into stirring, homogeneous under stirring, vacuumized conditions, it is for use after cooling;
C is added to the homogeneous object obtained by step (4) at (5) 70 DEG C, continues homogeneous, D phases are added after the completion, it is equal to continue stirring It is even;
E is added in the homogeneous object obtained by step (5) at (6) 45 DEG C and is stirred evenly;
(7) to plate, filtering and discharging, standing are to be checked after the assay was approved.
CN201810566057.6A 2018-06-04 2018-06-04 Children skin barrier repair moisturizing cream and preparation method thereof Active CN108524305B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201810566057.6A CN108524305B (en) 2018-06-04 2018-06-04 Children skin barrier repair moisturizing cream and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201810566057.6A CN108524305B (en) 2018-06-04 2018-06-04 Children skin barrier repair moisturizing cream and preparation method thereof

Publications (2)

Publication Number Publication Date
CN108524305A true CN108524305A (en) 2018-09-14
CN108524305B CN108524305B (en) 2021-04-16

Family

ID=63470203

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201810566057.6A Active CN108524305B (en) 2018-06-04 2018-06-04 Children skin barrier repair moisturizing cream and preparation method thereof

Country Status (1)

Country Link
CN (1) CN108524305B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288751A (en) * 2018-11-02 2019-02-01 蝶柔化妆品(浙江)有限公司 Bamboo charcoal deep cleansing mask and preparation method thereof
CN110693742A (en) * 2019-10-12 2020-01-17 福建省梦娇兰日用化学品有限公司 Infant moisturizing cream prepared by using microfiltration, concentration and extraction technology
CN112022785A (en) * 2020-10-08 2020-12-04 福建省梦娇兰日用化学品有限公司 Children moisturizer containing camellia anti-pollution components and preparation method thereof
CN113384514A (en) * 2021-06-03 2021-09-14 绽妍生物科技有限公司 Children emollient containing lactobacillus fermentation extract and preparation method thereof
CN116019759A (en) * 2023-03-03 2023-04-28 杨森 Two-in-one composition for repairing, moisturizing, washing hair and bathing children

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658470A (en) * 2009-09-18 2010-03-03 北京欧凯纳斯科技有限公司 Moisturizer and preparation method thereof
CN103565727A (en) * 2013-11-06 2014-02-12 中国科学院西北高原生物研究所 Lycium ruthenicum mill moisturizing and whitening cream and preparation method thereof
CN107898671A (en) * 2017-12-19 2018-04-13 广州汇川医药科技有限公司 A kind of alligator oil restorative facial cream and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101658470A (en) * 2009-09-18 2010-03-03 北京欧凯纳斯科技有限公司 Moisturizer and preparation method thereof
CN103565727A (en) * 2013-11-06 2014-02-12 中国科学院西北高原生物研究所 Lycium ruthenicum mill moisturizing and whitening cream and preparation method thereof
CN107898671A (en) * 2017-12-19 2018-04-13 广州汇川医药科技有限公司 A kind of alligator oil restorative facial cream and preparation method thereof

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109288751A (en) * 2018-11-02 2019-02-01 蝶柔化妆品(浙江)有限公司 Bamboo charcoal deep cleansing mask and preparation method thereof
CN110693742A (en) * 2019-10-12 2020-01-17 福建省梦娇兰日用化学品有限公司 Infant moisturizing cream prepared by using microfiltration, concentration and extraction technology
CN112022785A (en) * 2020-10-08 2020-12-04 福建省梦娇兰日用化学品有限公司 Children moisturizer containing camellia anti-pollution components and preparation method thereof
CN113384514A (en) * 2021-06-03 2021-09-14 绽妍生物科技有限公司 Children emollient containing lactobacillus fermentation extract and preparation method thereof
CN113384514B (en) * 2021-06-03 2023-03-24 绽妍生物科技有限公司 Children emollient containing lactobacillus fermentation extract and preparation method thereof
CN116019759A (en) * 2023-03-03 2023-04-28 杨森 Two-in-one composition for repairing, moisturizing, washing hair and bathing children

Also Published As

Publication number Publication date
CN108524305B (en) 2021-04-16

Similar Documents

Publication Publication Date Title
CN108524305A (en) A kind of child skin barrier repairs moisturiser and preparation method thereof
CN104958247B (en) A kind of body lotion containing nostoc sphaeroids kutz extractive and preparation method thereof
CN107007492B (en) A kind of makeup remover and preparation method thereof
CN105748343B (en) A kind of natural plant extracts composition and its application in cosmetics
CN107951771A (en) A kind of baby child releives moisturizing skin care creams and preparation method thereof
CN106726769A (en) A kind of peony seed oil anti-apolexis composition and preparation method thereof
CN109966186A (en) A kind of moisturizing maintenance composition of releiving of the hot spring containing mineral
CN108969433A (en) Double-colored facial treatment mask and preparation method thereof with whitening, moisturizing and Shu Min effect
CN108542870B (en) Mild soothing infant face cream
CN108685758A (en) Moisturizing emulsion and preparation method thereof containing fucoidin
CN106619337A (en) Crowfoot crack resistant cream for infants and a preparing method thereof
CN108743474A (en) A kind of ointment shape baby's diaper ointment and preparation method thereof
CN107233236A (en) A kind of fair-skinned bright fine flour frost and preparation method thereof
CN105395442A (en) Natural plant long-lasting moisturizing composition and use thereof
CN110507574A (en) One kind is releived moisturizing Multifunctional sleeping frost and preparation method thereof
CN108852912A (en) A kind of skin-moisturizing, skin lotion and preparation method thereof
CN109260075A (en) A kind of anti-acne opsonic water
CN108125810A (en) A kind of compound moisturizing remediation composition and its preparation method and application
CN108938508B (en) Fig fruit extract with sun-screening and synergistic effects and application thereof
CN114366678A (en) Liquid skin-care cream and preparation method thereof
Li et al. Extraction, moisturizing activity and potential application in skin cream of Akebia trifoliata (Thunb.) Koidz polysaccharide
CN114224764A (en) Bath lotion composition suitable for various surface active systems and preparation process thereof
CN108653176A (en) A kind of crease-resistant remediation composition and its application in cosmetics
CN115607476B (en) Composition with moisturizing and antioxidation effects and application thereof
CN111110614A (en) Skin whitening effect of tricholoma matsutake extract composition

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20190722

Address after: 230022 No. 506, Building 32, No. 210 Jixi Road, Shushan District, Hefei City, Anhui Province

Applicant after: Yang Sen

Applicant after: Guangzhou Pharmacist Medical Technology Co., Ltd.

Address before: 230022 No. 506, Building 32, No. 210 Jixi Road, Shushan District, Hefei City, Anhui Province

Applicant before: Yang Sen

TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20201110

Address after: 230022 No. 506, Building 32, No. 210 Jixi Road, Shushan District, Hefei City, Anhui Province

Applicant after: Yang Sen

Applicant after: Zhang Xuejun

Applicant after: Zhang Bo

Address before: No.506, building 32, No.210 Jixi Road, Shushan District, Hefei City, Anhui Province

Applicant before: Yang Sen

Applicant before: Guangzhou Pharmacist Medical Technology Co.,Ltd.

TA01 Transfer of patent application right
GR01 Patent grant
GR01 Patent grant