CN108477209B - Disinfectant and preparation method thereof - Google Patents
Disinfectant and preparation method thereof Download PDFInfo
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- CN108477209B CN108477209B CN201810542085.4A CN201810542085A CN108477209B CN 108477209 B CN108477209 B CN 108477209B CN 201810542085 A CN201810542085 A CN 201810542085A CN 108477209 B CN108477209 B CN 108477209B
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
- A01N33/02—Amines; Quaternary ammonium compounds
- A01N33/12—Quaternary ammonium compounds
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Abstract
The invention provides a disinfectant, which comprises the following components in parts by weight: 3-17 parts of hydrogen peroxide, 0.1-10 parts of dodecyl dimethyl benzyl ammonium halide, 1-5 parts of cosolvent, 1-5 parts of stabilizer and 60-95 parts of water. The invention remarkably improves the sterilization and disinfection capability of the disinfectant by compounding the hydrogen peroxide and the dodecyl dimethyl benzyl ammonium halide, and avoids the carcinogenic and easily-corrosive risks of adding high-efficiency disinfectants such as formaldehyde and acid in the traditional method. The two main antibacterial components and other surfactants are not mutually conflicted, the respective effects are enhanced by the compound use, and the compound disinfectant belongs to a compound disinfectant with low toxicity, quick response, high efficiency, broad spectrum and low corrosivity.
Description
Technical Field
The invention relates to the technical field of disinfection, and particularly relates to a disinfectant and a preparation method thereof.
Background
The hydrogen peroxide is a peroxide disinfectant, and can form hydroxyl free radicals and active derivatives with strong oxidizing capability in water, so that cell membranes and protoplasm of microorganisms can be damaged to achieve the aim of sterilization. The hydrogen peroxide has strong oxidizing ability and wide bactericidal spectrum, can effectively kill various bacteria propagules, fungi, tubercle bacillus and various viruses, is widely applied in many fields, is commonly used for cleaning wounds and locally disinfecting and resisting bacteria, and can also be used for disinfecting tableware, clothes, drinking water, contact lenses and heat-labile plastic products. However, the relatively unstable nature of hydrogen peroxide and the inefficient killing efficacy against spores limit its further widespread use.
In the prior art, a Chinese patent with publication number CN102696674A reports a low-concentration hydrogen peroxide compound disinfectant (the mass concentration of hydrogen peroxide is 0.1-1%) added with alkyl ammonium oxide, a metal ion complexing agent and an inorganic acid, and quantitative sterilization experiments are carried out, and the result shows that the hydrogen peroxide compound disinfectant has a good killing effect on staphylococcus aureus, escherichia coli, pseudomonas aeruginosa and candida albicans. Chinese patent application No. CN101032254A reports a hydrogen peroxide air disinfectant with the addition of a polyhydroxy polymer and peracetic acid. Chinese patent application No. CN101053330A reports a technology for improving the bactericidal activity of hydrogen peroxide by adding various acids, acid anhydrides and organic alcohol molecules to improve the effective action concentration and stability of hydrogen peroxide. Chinese patent application No. CN1379983A discloses a composite disinfectant liquid containing peroxydicarboxylic acid, urea and hydrogen peroxide as main sterilization active substances. Although the sterilizing effect and stability of the sterilizing liquid are improved to a certain extent, the sterilizing liquid is added with acidic substances, and the service life and the service performance of a sterilized object are greatly influenced by electrochemical corrosion generated in the sterilizing liquid by the acidic substances.
Disclosure of Invention
The invention aims to provide a disinfectant with low electrochemical corrosion behavior on the premise of ensuring the sterilization effect and a preparation method thereof.
In order to achieve the above object, the present invention provides the following technical solutions:
the invention provides a disinfectant, which comprises the following components in parts by weight:
preferably, the disinfectant comprises the following components in parts by weight:
preferably, the mass concentration of the hydrogen peroxide is 30-60%.
Preferably, the dodecyl dimethyl benzyl ammonium halide is dodecyl dimethyl benzyl ammonium chloride and/or dodecyl dimethyl benzyl ammonium bromide.
Preferably, the cosolvent is one or more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, tween-80, PEG-600, PEG200, PEG300 and PEG 400.
Preferably, the stabilizer is one or more of ethylenediamine tetraacetic acid, diethylenetriamine pentaacetic acid and N-hydroxyethyl ethylenediamine triacetic acid.
The invention also provides a preparation method of the disinfectant, which comprises the following steps:
mixing hydrogen peroxide, dodecyl dimethyl benzyl ammonium halide, cosolvent, stabilizer and water to obtain the disinfectant.
Preferably, the mixing temperature is 15-35 ℃.
Preferably, the mixing is carried out under stirring or shaking conditions.
The invention provides a disinfectant, which comprises the following components in parts by weight: 3-17 parts of hydrogen peroxide, 0.1-10 parts of dodecyl dimethyl benzyl ammonium halide, 1-5 parts of cosolvent, 1-5 parts of stabilizer and 60-95 parts of water. The invention remarkably improves the sterilization and disinfection capability of the disinfectant by compounding the hydrogen peroxide and the dodecyl dimethyl benzyl ammonium halide, and avoids the carcinogenic and easily-corrosive risks of adding high-efficiency disinfectants such as formaldehyde and acid in the traditional method. The two main antibacterial components and other surfactants are not mutually conflicted, the respective effects are enhanced by the compound use, and the compound disinfectant belongs to a compound disinfectant with low toxicity, quick response, high efficiency, broad spectrum and low corrosivity.
Drawings
FIG. 1 is a schematic diagram showing the appearance of the disinfectant of example 1 before and after a corrosion test on 316 stainless steel, copper sheets and aluminum sheets.
Detailed Description
The invention provides a disinfectant, which comprises the following components in parts by weight:
in the present invention, all the raw material components are commercially available products well known to those skilled in the art unless otherwise specified.
The disinfectant comprises 3-17 parts by weight of hydrogen peroxide, preferably 5-10 parts by weight, and more preferably 6-8 parts by weight. In the present invention, the mass concentration of the hydrogen peroxide is preferably 30% to 60%, more preferably 35% to 55%, and most preferably 40% to 50%.
Based on the mass of hydrogen peroxide, the disinfectant comprises 0.1-10 parts by weight of dodecyl dimethyl benzyl ammonium halide, preferably 3-7 parts by weight, and more preferably 4-6 parts by weight. In the present invention, the dodecyldimethylbenzyl ammonium halide is preferably dodecyldimethylbenzyl ammonium chloride and/or dodecyldimethylbenzyl ammonium bromide; when the dodecyl dimethyl benzyl ammonium halide is two selected from the above specific choices, the ratio of each substance is not particularly limited in the present invention, and the substances can be mixed in any ratio.
In the invention, the dodecyl dimethyl ammonium halide and the hydrogen peroxide are compounded to play a good synergistic role in sterilization, the sterilization effect of the dodecyl dimethyl ammonium halide is 1+1>2, and the serious electrochemical corrosion generated when the sterilization effect is improved by adding an acidic substance in the traditional method is avoided.
Based on the mass of hydrogen peroxide, the disinfectant comprises 1-5 parts by weight of cosolvent, preferably 2-4 parts by weight, and more preferably 2.5-3.5 parts by weight. In the invention, the cosolvent is one or more of sodium dodecyl sulfate, sodium dodecyl benzene sulfonate, tween-80, PEG-600, PEG200, PEG300 and PEG 400; in the present invention, when the number of the co-solvents is two or more of the above specific choices, the ratio of each substance is not particularly limited, and the co-solvents may be mixed in any ratio; in the present invention, the co-solvent is preferably 1 of the above specific choices.
In the present invention, the cosolvent functions as a surfactant to accelerate dissolution and solubilization of the dodecyldimethylbenzyl ammonium halide component therein.
Based on the mass of hydrogen peroxide, the disinfectant comprises 1-5 parts by weight of a stabilizer, preferably 2-4 parts by weight, and more preferably 2.5-3.5 parts by weight. In the invention, the stabilizer is preferably one or more of ethylenediamine tetraacetic acid, diethylenetriamine pentaacetic acid and N-hydroxyethyl ethylenediamine triacetic acid; in the present invention, when the stabilizers are two or more selected from the above specific choices, the ratio of each substance is not particularly limited, and the substances may be mixed in an arbitrary ratio; in the present invention, the stabilizer is preferably 1 of the above-mentioned specific choices.
In the present invention, the stabilizer has a certain oxidation resistance, can form a stable complex with metal ions, can be firmly bonded to general impurities, has a certain high temperature resistance, and prevents decomposition of hydrogen peroxide.
The disinfectant comprises 60-95 parts by weight of water, preferably 70-90 parts by weight of water, and more preferably 75-85 parts by weight of hydrogen peroxide. The present invention is not limited to any particular kind of water, and any kind of water known to those skilled in the art may be used.
The invention also provides a preparation method of the disinfectant, which comprises the following steps:
mixing hydrogen peroxide, dodecyl dimethyl benzyl ammonium halide, cosolvent, stabilizer and water to obtain the disinfectant.
In the present invention, the mixing temperature is preferably 15 to 35 ℃, more preferably 20 to 30 ℃, and most preferably 22 to 28 DEG C
In the present invention, the mixing is preferably performed under stirring or shaking. The invention has no special limitation on the stirring or oscillating speed and time, and can fully mix all the components in the mixed solution.
The order of addition of the materials in the mixing is not particularly limited in the present invention, and the mixing may be performed by a mixing order known to those skilled in the art.
In a particular embodiment of the invention, said mixing preferably comprises the following steps:
1) mixing a stabilizer, a cosolvent and water;
2) adding dodecyl dimethyl benzyl ammonium halide and hydrogen peroxide into the mixed solution obtained in the step 1) in sequence.
The disinfecting liquids provided by the present invention are described in detail with reference to the following examples, which should not be construed as limiting the scope of the present invention.
Example 1
Respectively weighing 4 parts by weight of Ethylene Diamine Tetraacetic Acid (EDTA) and 4 parts by weight of sodium dodecyl sulfate, adding the mixture into 83 parts by weight of water, and completely dissolving the mixture by oscillating and stirring;
under the condition of room temperature, 4 parts by weight of dodecyl dimethyl benzyl ammonium chloride is added into the solution and stirred until the dodecyl dimethyl benzyl ammonium chloride is completely dissolved, and the dissolved solution is uniformly mixed with 5 parts by weight of 60% hydrogen peroxide to obtain the disinfectant.
Example 2
Respectively weighing 4 parts by weight of Ethylene Diamine Tetraacetic Acid (EDTA) and 4 parts by weight of sodium dodecyl sulfate, adding the mixture into 83 parts by weight of water, and completely dissolving the mixture by oscillating and stirring;
under the condition of room temperature, 4 parts by weight of dodecyl dimethyl benzyl ammonium bromide is added into the solution and stirred until the dodecyl dimethyl benzyl ammonium bromide is completely dissolved, and the dissolved solution is uniformly mixed with 5 parts by weight of 60% hydrogen peroxide to obtain the disinfectant.
Example 3
Respectively weighing 4 parts by weight of Ethylene Diamine Tetraacetic Acid (EDTA) and 4 parts by weight of sodium dodecyl sulfate, adding the materials into 71.33 parts by weight of water, and completely dissolving the materials by oscillating and stirring;
under the condition of room temperature, 2 parts by weight of dodecyl dimethyl benzyl ammonium bromide and 2 parts by weight of dodecyl dimethyl benzyl ammonium chloride are added into the solution and stirred until the dodecyl dimethyl benzyl ammonium bromide and the dodecyl dimethyl benzyl ammonium chloride are completely dissolved, and the dissolved solution is uniformly mixed with 16.67 parts by weight of hydrogen peroxide with the mass concentration of 30% to obtain the disinfectant.
Comparative example 1
Respectively weighing 4 parts by weight of Ethylene Diamine Tetraacetic Acid (EDTA) and 4 parts by weight of sodium dodecyl sulfate, adding the materials into 87 parts by weight of water, and completely dissolving the materials by oscillating and stirring;
and (3) uniformly mixing the solution with 5 parts by weight of 60% hydrogen peroxide at room temperature to obtain the disinfectant.
Comparative example 2
Respectively weighing 4 parts by weight of Ethylene Diamine Tetraacetic Acid (EDTA) and 4 parts by weight of sodium dodecyl sulfate, adding the materials into 75.33 parts by weight of water, and completely dissolving the materials by oscillating and stirring;
and (3) uniformly mixing the solution with 16.67 parts by weight of 30% hydrogen peroxide at room temperature to obtain the disinfectant.
Comparative example 3
Respectively weighing 4 parts by weight of Ethylene Diamine Tetraacetic Acid (EDTA) and 4 parts by weight of sodium dodecyl sulfate, adding the materials into 88 parts by weight of water, and completely dissolving the materials by oscillating and stirring;
and (3) uniformly mixing the solution with 4 parts by weight of dodecyl dimethyl benzyl ammonium chloride at room temperature to obtain the disinfectant.
Comparative example 4
Respectively weighing 4 parts by weight of Ethylene Diamine Tetraacetic Acid (EDTA) and 4 parts by weight of sodium dodecyl sulfate, adding the materials into 88 parts by weight of water, and completely dissolving the materials by oscillating and stirring;
and (3) uniformly mixing the solution with 4 parts by weight of dodecyl dimethyl benzyl ammonium bromide at room temperature to obtain the disinfectant.
Example 4
The disinfectant prepared in example 1 was tested for corrosion performance as follows:
and respectively soaking 316 stainless steel, the copper sheet and the aluminum sheet in the disinfectant for 72 hours, wherein the quality of the copper sheet, the aluminum sheet and the 316 stainless steel before and after soaking has no obvious statistical difference, and no serious corrosion occurs.
The corrosion results are shown in fig. 1: the copper plate and the aluminum plate have small-area corrosive dark spots, and are only slightly corroded, the 316 stainless steel has no corrosive dark spots, and the stainless steel has better tolerance to the 316 stainless steel, the copper sheet and the aluminum sheet, wherein the tolerance to the 316 stainless steel is the best.
The disinfectant prepared in examples 1 to 3 and comparative examples 1 to 4 was tested for the killing effect on Bacillus subtilis var niger spores, specifically as follows:
the specific test results are shown in table 1:
TABLE 1 disinfectant solutions prepared in examples 1 to 3 and comparative examples 1 to 4 for treating black-colored Bacillus subtilis sprouts
Spore-killing effect
Note: the horizontal bar is drawn to show that the sampling test of the sampling point is not carried out at the point because the calculation and the actual fitting of the killing curve are better and the trend of obvious gentle and slow change is already shown.
As can be seen from the table above, the sterilizing liquid of the invention can achieve a log value of killing spores within 45min of more than 6, and completely meets the sterilization standard specified by FDA and Disinfection technical Specification.
The foregoing is merely a preferred embodiment of the invention and is not intended to limit the invention in any manner. It should be noted that, for those skilled in the art, without departing from the principle of the present invention, several improvements and modifications can be made, and these improvements and modifications should also be construed as the protection scope of the present invention.
Claims (4)
1. The disinfectant consists of the following components in parts by weight:
the mass concentration of the hydrogen peroxide is 30-60%;
the cosolvent is sodium dodecyl sulfate;
the stabilizer is ethylene diamine tetraacetic acid;
the preparation method of the disinfectant comprises the following steps:
mixing hydrogen peroxide, dodecyl dimethyl benzyl ammonium halide, cosolvent, stabilizer and water until all the components are dissolved to obtain a disinfectant;
the mixing is carried out under stirring or shaking conditions;
the dodecyl dimethyl benzyl ammonium halide is dodecyl dimethyl benzyl ammonium bromide.
2. The disinfecting solution of claim 1, wherein the disinfecting solution consists of the following components in parts by weight:
the mass concentration of the hydrogen peroxide is 30-60%;
the cosolvent is sodium dodecyl sulfate;
the stabilizer is ethylene diamine tetraacetic acid;
the preparation method of the disinfectant comprises the following steps:
mixing hydrogen peroxide, dodecyl dimethyl benzyl ammonium halide, cosolvent, stabilizer and water until all the components are dissolved to obtain a disinfectant;
the mixing is carried out under stirring or shaking conditions;
the dodecyl dimethyl benzyl ammonium halide is dodecyl dimethyl benzyl ammonium bromide.
3. The method for preparing the disinfecting solution of any one of claims 1 to 2, comprising the steps of:
mixing hydrogen peroxide, dodecyl dimethyl benzyl ammonium halide, cosolvent, stabilizer and water until all the components are dissolved to obtain a disinfectant;
the mixing is carried out under stirring or shaking.
4. The method of claim 3, wherein the mixing temperature is 15 to 35 ℃.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109907070A (en) * | 2019-04-04 | 2019-06-21 | 上海恤世化学技术有限公司 | A kind of thimerosal and preparation method |
| CN110115271A (en) * | 2019-04-22 | 2019-08-13 | 肇庆大华农生物药品有限公司 | A kind of compound disinfectant with hydrogen peroxide dilution, purposes and the method for egg surface sterilization |
| CN114747568A (en) * | 2022-04-27 | 2022-07-15 | 山东利尔康医疗科技股份有限公司 | Medium-level disinfection wet tissue and preparation method thereof |
| CN115245174B (en) * | 2022-08-15 | 2023-06-13 | 山东大学 | Water-soluble compound potassium hydrogen persulfate disinfectant and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1096631A (en) * | 1994-05-20 | 1994-12-28 | 李潜德 | " hydro-peening (spilling) goes out "---space spraying and the good long-acting sterilized solution of washing performance |
| CN101553202A (en) * | 2006-12-13 | 2009-10-07 | 森特尼尔投资有限公司 | Mild composition for skin disinfection |
| CN102273488A (en) * | 2011-06-22 | 2011-12-14 | 李翰实 | Nascent oxygen high speed specific bactericidal disinfectant |
| WO2015104687A1 (en) * | 2014-01-13 | 2015-07-16 | 99 Holding S.A.R.L. | Activated hydrogen peroxide biocide composition |
| WO2015196299A1 (en) * | 2014-06-27 | 2015-12-30 | Kane Biotech Inc. | Antimicrobial-antibiofilm compositions and methods of use thereof for personal care products |
| CN107079925A (en) * | 2017-05-08 | 2017-08-22 | 李潜德 | Deodorization and sterilization hydro-peening liquid clean may just as well excellent and available for gas-solid liquid environment |
-
2018
- 2018-05-30 CN CN201810542085.4A patent/CN108477209B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1096631A (en) * | 1994-05-20 | 1994-12-28 | 李潜德 | " hydro-peening (spilling) goes out "---space spraying and the good long-acting sterilized solution of washing performance |
| CN101553202A (en) * | 2006-12-13 | 2009-10-07 | 森特尼尔投资有限公司 | Mild composition for skin disinfection |
| CN102273488A (en) * | 2011-06-22 | 2011-12-14 | 李翰实 | Nascent oxygen high speed specific bactericidal disinfectant |
| WO2015104687A1 (en) * | 2014-01-13 | 2015-07-16 | 99 Holding S.A.R.L. | Activated hydrogen peroxide biocide composition |
| WO2015196299A1 (en) * | 2014-06-27 | 2015-12-30 | Kane Biotech Inc. | Antimicrobial-antibiofilm compositions and methods of use thereof for personal care products |
| CN107079925A (en) * | 2017-05-08 | 2017-08-22 | 李潜德 | Deodorization and sterilization hydro-peening liquid clean may just as well excellent and available for gas-solid liquid environment |
Non-Patent Citations (1)
| Title |
|---|
| 过氧化氢泡沫消毒剂的实验研究;朱大兰;《中国优秀硕士学位论文全文数据库 医药卫生科技辑》;20051015(第06期);第18页最后1段、第21页倒数第2段、第24页第1段、第25页第1段 * |
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