CN108473589B - 结合前列腺特异性膜抗原(psma)的分子 - Google Patents
结合前列腺特异性膜抗原(psma)的分子 Download PDFInfo
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- CN108473589B CN108473589B CN201780006227.9A CN201780006227A CN108473589B CN 108473589 B CN108473589 B CN 108473589B CN 201780006227 A CN201780006227 A CN 201780006227A CN 108473589 B CN108473589 B CN 108473589B
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1600559.7A GB201600559D0 (en) | 2016-01-12 | 2016-01-12 | Therapeutic molecules |
| GB1600559.7 | 2016-01-12 | ||
| GB1605770.5 | 2016-04-04 | ||
| GB201605770 | 2016-04-04 | ||
| GB201605763 | 2016-04-04 | ||
| GB1605763.0 | 2016-04-04 | ||
| PCT/GB2017/050075 WO2017122018A1 (en) | 2016-01-12 | 2017-01-12 | Molecules that bind prostate specific membrane antigen (psma) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108473589A CN108473589A (zh) | 2018-08-31 |
| CN108473589B true CN108473589B (zh) | 2023-05-02 |
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| GB201711068D0 (en) * | 2017-07-10 | 2017-08-23 | Crescendo Biologics Ltd | Therapeutic molecules binding PSMA |
| JP7312168B2 (ja) * | 2017-11-13 | 2023-07-20 | クレッシェンド、バイオロジックス、リミテッド | Cd137に結合するシングルドメイン抗体 |
| GB201802573D0 (en) | 2018-02-16 | 2018-04-04 | Crescendo Biologics Ltd | Therapeutic molecules that bind to LAG3 |
| GB201818460D0 (en) * | 2018-11-13 | 2018-12-26 | Crescendo Biologics Ltd | Single domain antibodies that bind human serum albumin |
| AU2020252556B2 (en) * | 2019-04-05 | 2026-02-05 | Teneobio, Inc. | Heavy chain antibodies binding to PSMA |
| KR102260478B1 (ko) * | 2019-08-19 | 2021-06-02 | 연세대학교 산학협력단 | 일나트륨 요소화물 결정 용해용 조성물 |
| CN111303288B (zh) * | 2020-03-04 | 2020-12-25 | 和铂医药(苏州)有限公司 | 一种分离的结合抗原psma的蛋白及其用途 |
| JP2023532807A (ja) | 2020-07-08 | 2023-07-31 | ラヴァ・セラピューティクス・エヌ・ヴイ | Psma及びガンマ-デルタt細胞受容体に結合する抗体 |
| CN112480260B (zh) * | 2020-12-09 | 2022-03-08 | 福州迈新生物技术开发有限公司 | 抗psma蛋白单克隆抗体、细胞系及其制备方法和应用 |
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| EP4392454A4 (en) * | 2021-08-27 | 2025-10-15 | Janssen Biotech Inc | ANTI-PSMA ANTIBODIES AND THEIR USES |
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| CN116271081A (zh) * | 2023-04-04 | 2023-06-23 | 上海愿智生物技术有限公司 | 一种抗体偶联药物yc1605及其药物组合物和应用 |
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| GB2398784B (en) | 2003-02-26 | 2005-07-27 | Babraham Inst | Removal and modification of the immunoglobulin constant region gene cluster of a non-human mammal |
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| WO2006089230A2 (en) | 2005-02-18 | 2006-08-24 | Medarex, Inc. | Human monoclonal antibodies to prostate specific membrane antigen (psma) |
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| CN116478293A (zh) | 2023-07-25 |
| JP7190901B2 (ja) | 2022-12-16 |
| CN108473590A (zh) | 2018-08-31 |
| US20230406954A1 (en) | 2023-12-21 |
| JP2019511201A (ja) | 2019-04-25 |
| EP3402825A1 (en) | 2018-11-21 |
| CN108473590B (zh) | 2023-04-14 |
| US20200392244A1 (en) | 2020-12-17 |
| WO2017122017A1 (en) | 2017-07-20 |
| US20190023807A1 (en) | 2019-01-24 |
| US20220112305A1 (en) | 2022-04-14 |
| US11746158B2 (en) | 2023-09-05 |
| US11236174B2 (en) | 2022-02-01 |
| WO2017122019A1 (en) | 2017-07-20 |
| JP7450594B2 (ja) | 2024-03-15 |
| JP2022046662A (ja) | 2022-03-23 |
| CN108473589A (zh) | 2018-08-31 |
| WO2017122018A1 (en) | 2017-07-20 |
| JP2019506155A (ja) | 2019-03-07 |
| EP3402824A1 (en) | 2018-11-21 |
| US10975161B2 (en) | 2021-04-13 |
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