CN108444760A - A kind of quantitative reagent acquisition CD - Google Patents
A kind of quantitative reagent acquisition CD Download PDFInfo
- Publication number
- CN108444760A CN108444760A CN201810450968.2A CN201810450968A CN108444760A CN 108444760 A CN108444760 A CN 108444760A CN 201810450968 A CN201810450968 A CN 201810450968A CN 108444760 A CN108444760 A CN 108444760A
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- quantitative
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- 239000003153 chemical reaction reagent Substances 0.000 title claims abstract description 55
- 239000012530 fluid Substances 0.000 claims abstract description 19
- 230000002459 sustained effect Effects 0.000 claims description 6
- 238000001514 detection method Methods 0.000 abstract description 11
- 238000000034 method Methods 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 description 11
- 239000008280 blood Substances 0.000 description 11
- 238000012360 testing method Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 3
- 210000002798 bone marrow cell Anatomy 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 208000014951 hematologic disease Diseases 0.000 description 2
- 208000019838 Blood disease Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 210000001772 blood platelet Anatomy 0.000 description 1
- 238000009534 blood test Methods 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 230000000093 cytochemical effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007723 die pressing method Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 238000005530 etching Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 208000018706 hematopoietic system disease Diseases 0.000 description 1
- 208000007475 hemolytic anemia Diseases 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 230000007480 spreading Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Hydrology & Water Resources (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention discloses a kind of quantitative reagents to acquire CD, including CD, the guiding device being located on CD and the proportioning device being located on CD.Guiding device includes diversion pipe, the connecting tube being located on CD, the fluid stopping pipe being connect with connecting tube and the delivery line being connect with fluid stopping pipe；The junction of fluid stopping pipe and delivery line is equipped with changeover portion；The minimum range of changeover portion and cd centre is less than the minimum range of conduit and cd centre.The minimum range of run-off and cd centre is less than the minimum range in quantitative pond and cd centre.Proportioning device includes the quantitative pond being connect with diversion pipe, the run-off being located on CD and the conduit being located on CD.One end of conduit is connect with quantitative pond, and the other end is connect with run-off.The present invention can carry out quantitative collection to the reagent used in medical detection process, and picking rate is fast, and acquisition precision is high.
Description
Technical field
The present invention relates to blood testing fields, and in particular to a kind of quantitative reagent acquisition CD.
Background technology
Clinical blood detection can be divided into blood generally detect, the test in laboratory of hemolytic anemia, bone marrow cell detect,
Bracket for blood grouping and cross match blood test.It can detect that the hematology of common hematological diseases holds sign.
One of the most common is that blood generally detects（That is blood routine）.I.e. to red blood cell, leucocyte and blood platelet these three
The amount and matter of system are detected and analyze.It is also wanted with the relevant detection of various diseases if blood disease is in addition to blood routine to be detected
Carry out bone marrow cell detection, blood cyto-chemical stain analysis etc.；It is main for the blood testing project of hepatopathy and kidney patient
Detection etc. including liver function, renal function；And for some communicable diseases, the detection of antibodies in blood is the weight of diagnosis
It will foundation.
Traditional detection means is detected for some index or certain specific substance after sample collection, is examined
Ranging sequence is more, and the detection of a routine needs more more equipment operations of people, and detection time is long, and testing cost is high, is its outstanding feature.
Especially it is certain need to be detected using reagent in the case of, a variety of interference such as sample error, instrumental error, human error
Factor can all influence testing result.Although the spreading speed of automatic detection system is obviously accelerated in recent years, easily tens
Ten thousand purchase costs even up to a million, general hospital and testing agency are difficult to bear.Especially blood testing parameter is various, inspection
Measurement equipment inevitably has specific aim again, also exacerbates this trend from another point of view.
Invention content
The present invention is intended to provide a kind of quantitative reagent that can carry out quantitative collection to reagent acquires CD.
The present invention adopts the following technical scheme that：
A kind of quantitative reagent acquisition CD, including CD, the guiding device being located on CD and the quantitative dress being located on CD
It sets；
The guiding device includes diversion pipe；
The proportioning device includes the quantitative pond being connect with diversion pipe, the run-off being located on CD and is located at leading on CD
Pipe；
One end of the conduit is connect with quantitative pond, and the other end is connect with run-off.
As further solution：The diversion pipe is connect with the trailing flank in quantitative pond.
As further solution：It further include reagent；The free end of the reagent and diversion pipe connects.
As further solution：The leading flank in the quantitative pond is located at each point and cd centre in sustained height
Distance it is equal；
The each point that the trailing flank in the quantitative pond is located in sustained height is equal at a distance from cd centre.
As further solution：The guiding device further includes the connecting tube being located on CD, connects with connecting tube
The fluid stopping pipe connect and the delivery line being connect with fluid stopping pipe；
The free end of the connecting tube is connect with quantitative pond.
As further solution：The connecting tube is connect with the trailing flank in quantitative pond.
Described in further solution：The junction of the fluid stopping pipe and delivery line is equipped with changeover portion；The mistake
The minimum range for crossing section and cd centre is less than the minimum range of conduit and cd centre.
As further solution：It further include the exhaust pipe being connect with run-off.
As further solution：The minimum range of the run-off and cd centre is less than in quantitative pond and CD
The minimum range of the heart.
The good effect that the present invention generates is as follows：
The acquisition precision higher of the present invention.The reagent of specified amount is injected into reagent or directly in reagent by staff
It is inside put into reagent packet, reagent when CD rotates in reagent flow to diversion pipe, is then transferred under the influence of centrifugal force
In quantitative pond, after quantitative pond is filled, extra part is transferred to run-off.Then, CD rotates backward, the examination in quantitative pond
Agent sequence passes through connecting tube, fluid stopping pipe, changeover portion and delivery line, is transferred to subsequent mixing pit or subsequent mixing apparatus
In.During changing, reagent collection capacity is exactly the capacity in quantitative pond, can carry out accurate quantitative collection to reagent.
The acquisition cost of the present invention is lower, collecting efficiency higher.Traditional acquisition mode is that artificial acquisition or machine are adopted
Collection, manually staff is operated using dropper, day equality when acquisition, the interference such as equipment precision, human error, operating error
Factor is very more, it is difficult to accurately be measured；Although it is very high that machine acquires precision, meet the equipment price of such precision
Also very high, it general hospital and also is difficult to receive using mechanism.What the present invention innovated uses optical-disk type design, passes through rule
It is very low that the production of modelling can be such that the cost of manufacture of CD drops to, and is only influenced by the accuracy of manufacture when especially CD acquires,
Various disturbing factors when artificial acquisition are thoroughly avoided, acquisition precision can be improved rapidly, are accomplished in terms of cost and efficiency
Extraordinary balance.
Description of the drawings
Fig. 1 is the structural diagram of the present invention；
Wherein：11 diversion pipes, 21 quantitative ponds, 22 run-offs, 23 conduits, 3 reagents, 31 connecting tubes, 32 fluid stopping pipes, 33 export
Pipe, 4 changeover portions, 5 exhaust pipes.
Specific implementation mode
With reference to Fig. 1, invention is further explained.
The present invention adopts the following technical scheme that：
A kind of quantitative reagent acquisition CD, including CD, the guiding device being located on CD and the quantitative dress being located on CD
It sets；
The guiding device includes diversion pipe 11；
The proportioning device includes the quantitative pond 21 being connect with diversion pipe 11, the run-off 22 being located on CD and is located on CD
Conduit 23；
One end of the conduit 23 is connect with quantitative pond 21, and the other end is connect with run-off 22.
As further solution：The diversion pipe 11 is connect with the trailing flank in quantitative pond 21.
As further solution：It further include reagent 3；The reagent 3 is connect with the free end of diversion pipe 11.
As further solution：The leading flank in the quantitative pond 21 is located in each point and CD in sustained height
The distance of the heart is equal；
The each point that the trailing flank in the quantitative pond 21 is located in sustained height is equal at a distance from cd centre.
As further solution：The guiding device further includes the connecting tube 31 and connecting tube being located on CD
The fluid stopping pipe 32 of 31 connections and the delivery line 33 being connect with fluid stopping pipe 32；
The free end of the connecting tube 31 is connect with quantitative pond 21.
As further solution：The connecting tube 31 is connect with the trailing flank in quantitative pond 21.
As further solution：The fluid stopping pipe 32 and the junction of delivery line 33 are equipped with changeover portion 4；The mistake
Cross the minimum range that section 4 is less than conduit 23 and cd centre with the minimum range of cd centre.
As further solution：It further include the exhaust pipe 5 being connect with run-off 22.
As further solution：The minimum range of the run-off 22 and cd centre is less than quantitative pond 21 and light
The minimum range of disk center.
The present invention needs to coordinate dedicated centrifugally operated equipment, each operation that CD is store in the equipment required
Rotation time and velocity of rotation.The centrifugally operated equipment repeats no more not within the protection domain of the application.
CD mentioned in the present invention is made of high molecule plastic, and reagent 3 and quantitative pond 21 etc. are using molding system
Make, diversion pipe 11 and conduit 23 etc. are made of accurate die pressing or etching, are integrated on a CD.
In use, suitable reagent is injected reagent 3, centrifugally operated equipment drives CD rotation, and reagent is in centrifugal force
Under the action of flow in quantitative pond 21 by diversion pipe 11.In order to further increase the simplicity of operation at this, CD is being made
Reagent can be made to packet to be potted directly into reagent 3 when making, when use punctures or the pressure by reagent to packaging bag
It is set to break automatically.
Diversion pipe 11 is connect with the lateral surface in quantitative pond 21, under the influence of centrifugal force, reagent will quantify from outside to inside
It fills in pond 21.After quantitative pond 21 is filled, extra reagent is transferred to by conduit 23 in run-off 22.Diversion pipe 11 and overflow
The junction in pond 22 is closer to cd centre, and the pressure of reagent is on the direction for flowing to run-off 22 in such diversion pipe 11
It continuously decreases, reagent is enable smoothly to flow into run-off 22.Meanwhile run-off 22 can make closer to cd centre
Diversion pipe 11 and the fluid pressure of 22 junction of run-off are consistently less than quantitative pond 21 and the fluid pressure at diversion pipe 11, avoid
Reagent when reagent is flowed out from quantitative pond 21 in run-off 22 also flows out therewith, and acquisition precision is caused to decline.
Reagent from outside to inside during quantitative pond 21 is filled, the air in quantitative pond 21 is extruded to run-off
In 22.With the rotation of CD, bubble that may be present can also be precipitated and be eventually transferred into run-off 22 in reagent, exist in this way
It carries out that the bubble in reagent can also be removed when quantitative collection simultaneously, ensures acquisition precision.
Quantitative pond 21 is leading flank close to the face of cd centre, is trailing flank far from the face in CD.Leading flank and rear side
Face is all made of cambered surface design, and center of arc overlaps with the center of CD, can ensure that reagent uniformly divides in quantitative pond 21 in this way
The gas for playing internal is all expressed in run-off 22 by cloth.Design is also for guarantee acquisition precision at this.
The minimum range of run-off 22 and cd centre is less than the minimum range in quantitative pond 21 and cd centre, in this way can
Ensure that the air pressure in quantitative pond 21 is consistently higher than the air pressure in run-off 22, when the gas in quantitative pond 21 is shifted to run-off 22
When, be not in resistance.
During into pond 21 are quantified, the atmospheric pressure in connecting tube 31 and quantitative pond 21 is more than conduit 23 and determines reagent
Measure the atmospheric pressure of 21 junction of pond.Therefore, reagent can be gradually filled with quantitative pond 21 rather than be flowed out from connecting tube 31.
Description below is made for pressure：Connecting tube 31 and the atmospheric pressure in quantitative pond 21 are provided by fluid stopping pipe 32, conduit
23 are mainly provided by conduit 23 with the atmospheric pressure for quantifying 21 junction of pond.Connecting tube 31 and conduit 23 are connected with the external world,
Be exactly medium in the two it is air, under the influence of centrifugal force, pressure is free air lift to supply.The pressure formula P of reference fluids=
ρ gh, identical in ρ and g, the size of pressure is determined by h.On the direction close to cd centre, connecting tube 31 and lead
When the diameter of pipe 23 is identical, when the length of connecting tube 31 is more than the length of conduit 23, connecting tube 31 and quantitative 21 junction of pond
Atmospheric pressure will be more than the atmospheric pressure of conduit 23 and quantitative 21 junction of pond.In actual product, connecting tube 31 and lead
Pipe 23 diameter is close, on the direction close to cd centre, the length of connecting tube 31 is far longer than the length of conduit 23, is exactly
In order to ensure existing always for pressure difference at this.
Run-off 22 also external an exhaust pipe 5, the free end of exhaust pipe 5 are connect with air, can make overflow in this way
Air pressure in pond 22 maintains an equal level with atmospheric pressure always, avoids generating back pressure in run-off 22 in quantitative collection.
After the completion of quantitative, CD rotates backward, and there are one opposite with CD rotation direction for the reagent tool in quantitative pond 21
Movement tendency, under the influence of centrifugal force, reagent sequence are transferred to rear by connecting tube 31, fluid stopping pipe 32 and delivery line 33
In mixing pit or mixing apparatus, subsequent detection work is carried out.
Finally it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than its limitations, although
Present invention has been described in detail with reference to the aforementioned embodiments, it will be understood by those of ordinary skill in the art that, still may be used
To modify to the technical solution recorded in previous embodiment or equivalent replacement of some of the technical features, and
These modifications or replacements, the spirit and model of technical solution of the embodiment of the present invention that it does not separate the essence of the corresponding technical solution
It encloses.
Claims (9)
1. a kind of quantitative reagent acquires CD, it is characterised in that：Including CD, the guiding device being located on CD and it is located at light
Proportioning device on disk；
The guiding device includes diversion pipe（11）；
The proportioning device includes and diversion pipe（11）The quantitative pond of connection（21）, the run-off that is located on CD（22）Be located at
Conduit on CD（23）；
The conduit（23）One end and quantitative pond（21）Connection, the other end and run-off（22）Connection.
2. a kind of quantitative reagent according to claim 1 acquires CD, it is characterised in that：The diversion pipe（11）With it is fixed
Measure pond（21）Trailing flank connection.
3. a kind of quantitative reagent according to claim 1 acquires CD, it is characterised in that：It further include reagent（3）；Institute
State reagent（3）With diversion pipe（11）Free end connection.
4. a kind of quantitative reagent according to claim 2 acquires CD, it is characterised in that：The quantitative pond（21）Before
The each point that side is located in sustained height is equal at a distance from cd centre；
The quantitative pond（21）The each point that is located in sustained height of trailing flank it is equal at a distance from cd centre.
5. a kind of quantitative reagent according to claim 1 acquires CD, it is characterised in that：The guiding device further includes
The connecting tube being located on CD（31）With connecting tube（31）The fluid stopping pipe of connection（32）With with fluid stopping pipe（32）The delivery line of connection
（33）；
The connecting tube（31）Free end and quantitative pond（21）Connection.
6. a kind of quantitative reagent according to claim 5 acquires CD, it is characterised in that：The connecting tube（31）With it is fixed
Measure pond（21）Trailing flank connection.
7. acquiring CD according to a kind of quantitative reagent that claim 5 is stated, it is characterised in that：The fluid stopping pipe（32）With export
Pipe（33）Junction be equipped with changeover portion（4）；The changeover portion（4）It is less than conduit with the minimum range of cd centre（23）With light
The minimum range of disk center.
8. a kind of quantitative reagent according to claim 1 acquires CD, it is characterised in that：Further include and run-off（22）
The exhaust pipe of connection（5）.
9. a kind of quantitative reagent according to claim 1 acquires CD, it is characterised in that：The run-off（22）With light
The minimum range of disk center is less than quantitative pond（21）With the minimum range of cd centre.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810450968.2A CN108444760A (en) | 2018-05-11 | 2018-05-11 | A kind of quantitative reagent acquisition CD |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810450968.2A CN108444760A (en) | 2018-05-11 | 2018-05-11 | A kind of quantitative reagent acquisition CD |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108444760A true CN108444760A (en) | 2018-08-24 |
Family
ID=63203068
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810450968.2A Pending CN108444760A (en) | 2018-05-11 | 2018-05-11 | A kind of quantitative reagent acquisition CD |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108444760A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109211860A (en) * | 2018-09-29 | 2019-01-15 | 厦门大学 | A kind of multinomial detection CD and detection method |
| CN109283174A (en) * | 2018-09-29 | 2019-01-29 | 厦门大学 | A kind of quantitative detection CD and detection method |
| CN112255038A (en) * | 2020-10-27 | 2021-01-22 | 冯英明 | Take groundwater water quality testing sampling device of formula mechanism is decided to atmospheric pressure |
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