CN202710548U - Detecting and analyzing meter for platelet aggregation function - Google Patents
Detecting and analyzing meter for platelet aggregation function Download PDFInfo
- Publication number
- CN202710548U CN202710548U CN 201220009721 CN201220009721U CN202710548U CN 202710548 U CN202710548 U CN 202710548U CN 201220009721 CN201220009721 CN 201220009721 CN 201220009721 U CN201220009721 U CN 201220009721U CN 202710548 U CN202710548 U CN 202710548U
- Authority
- CN
- China
- Prior art keywords
- sample
- cup
- platelet aggregation
- instrument
- syringe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Images
Abstract
The utility model provides a detecting and analyzing meter for a platelet aggregation function. The detecting and analyzing meter for the platelet aggregation function comprises a sample cup, a dilution cup, a detecting cup, a sample-bearing stage, a sampling needle, a sample-sucking injector, an aggregation-leading agent diluter and a diluent injector. The detecting and analyzing meter for the platelet aggregation function can achieve detecting of the aggregation function of platelets of a blood sample with only one citric acid anticoagulation blood sample. A principle that an electrical impedance method or a laser method is used for accurate detecting of the number of platelets in whole blood can be used in the meter. Detecting results created by the detecting and analyzing meter show that the platelet results obtained by the meter are good in repeatability.
Description
One, technical field
The utility model relates to a kind of detection platelet aggregation and detects analyser, and this instrument is estimated the platelet aggregation level by detecting tested blood sample in the variation of assembling Platelet quantity.The utility model belongs to the clinical laboratory medicine field.
Two, background technology
Platelet aggregation (or aggregation rate) is a hematoblastic critical function in the blood, is an important indicator of evaluating blood coagulation function.Existing platelet aggregation function detecting instrument mainly is that platelet aggregation Plasma Before And After (whole blood) optical density (or light transmittance energy) changes in blood plasma or the whole blood by detecting (to be called for short: optical method), or electrode is put into whole blood to be checked observe blood sample and add after the induced polymerization inhibitor blood platelet and be adsorbed on the electrode resistance that causes on the electrode and change and (be called for short: electric method).These instruments are owing to all respectively have a certain defect, detect such as optical method, electric method instrument that operation is more loaded down with trivial details, resultant error is larger.Also have and use blood analyser to detect the EDTA anticoagulated whole blood, and contrast citrate anticoagulation blood adds the variation of platelet counts after the induced polymerization inhibitor, carry out the method that platelet aggregation detects.The method need to adopt two parts of blood samples, and operating process relies on the manual blood analyser that cooperates to be carried out, and its automaticity is lower, and testing conditions (such as time, sample blending, temperature etc.) control is relatively poor, can't reach higher detection repeatability level.Whole bliid platelet analyzer of the present utility model, after sample being placed on the instrument load sample platform sample position, instrument provides stationary temperature, the principle according to electrical impedance or laser under the time of controlling and mixing condition realizes detecting, and testing process does not need artificial participation fully, and therefore easy to operate, result is repeated better.
Three, summary of the invention
A kind of platelet aggregation of the present utility model detects analyser, comprises sample cup, diluted cup, detection cup, load sample platform, sampling probe, suction sample syringe, induced polymerization inhibitor diluter, dilution syringe; Described sample cup is used for storing blood sample; Described diluted cup is used for once diluting blood sample; Described detection cup is used for the secondary dilution blood sample and detects blood sample; Described load sample platform is used for placing sample cup; Described suction sample syringe is communicated with sampling probe, is used for drawing blood sample to sample cup; Described induced polymerization inhibitor diluter is communicated with the induced polymerization inhibitor bottle, is used for adding induced polymerization inhibitor to sample cup; Described dilution syringe is communicated with the dilution bottle, is used for to diluted cup and detects cup adding dilution; Described sampling probe, suction sample syringe, induced polymerization inhibitor diluter, dilution syringe are moved by Electric Machine Control respectively; Described sampling probe is communicated with by pipeline and valve inhales sample syringe and dilution syringe; Described sampling probe with inhale after the sample syringe is communicated with, the blood sample in the sample cup added diluted cup and detect glass; Described sampling probe is with after the diluter syringe is communicated with, and dilution is added diluted cup and detects in the cup.The utility model is to realize automatically that according to the principle of electrical impedance or laser directly platelet Counting is assembled forward and backward platelet counts, makes evaluation to the blood sample platelet aggregation according to the variation of platelet counts.This instrument is placed in the sample position of load sample platform the whole sample cups that only portion need to be equipped with fresh citrate anticoagulation blood sample that detect of the platelet aggregation of a blood sample, instrument can automatically to sample blending, constant temperature, sampling, detection, be finished detection and report to platelet aggregation.In the process that detects, the load sample platform can make sample cup stop at vertical position to be convenient to sample sampling and to add induced polymerization inhibitor, also can be by motor-driven load sample platform respectively to left and right the to-and-fro movement that respectively is not more than an angle of 90 degrees degree, so that blood sample obtains continuing mixing in the sample cup.By this blood sample is assembled forward and backward repeated detection, average to the platelet count certificate of assembling forward and backward detection acquisition respectively, according to these two groups of average aggregation rate values of platelet counts mean value calculation acquisition blood platelet of same sample.
Four, description of drawings
Fig. 1 is the primary structure figure that the utility model platelet aggregation detects analyser.
Fig. 2 is the load sample table apparatus structural drawing (having the mixing function) that the utility model platelet aggregation detects analyser.
As shown in Figure 1, the platelet aggregation that the utility model discloses a kind of semi-automation detects analyser, the primary structure of this instrument comprises: 1, load sample platform, 2, suction needle, 3, diluted cup, 4, detect cup, 5, detection probe, sample suction pump when 6, detecting, 7, inhale the sample syringe, 8, the dilution syringe, 9, the dilution bottle, 10, induced polymerization inhibitor diluter, 11, induced polymerization inhibitor bottle, 12, induced polymerization inhibitor control T-valve, 13, filling induced polymerization inhibitor pin, 14, control dilution T-valve, 15, the primary structure part such as sample cup.
Five, embodiment
Design is further described to this utility model below in conjunction with accompanying drawing:
As shown in Figure 1, getting one is equipped with the fresh citrate anticoagulation blood sample of 500ul cup 15 and is placed in the instrument load sample platform 1 loading grade, anticoagulation weight range in this sample cup is at 200-800ul, instrument load sample platform is respectively to left and right respectively being not more than an angle of 90 degrees degree left and right sides reciprocating rotation mixing blood sample, the load sample platform rotate or when static under the sample rim of a cup along being not less than in the sample cup plane on the blood sample.Sample instrument sampling probe 2 behind load sample platform mixing gos deep into taking out simultaneously in the sample cup blood sample a certain amount of blood sample (20ul) under the assistance of diluter 7, then sampling probe changes blood sample in the diluted cup 3 over to, instrument injects the 2ml dilution by the diluent reagent bucket by diluter 8 and T-valve 14 synergies simultaneously in diluted cup, also inject the 2ml dilution in the cup 4 to detecting simultaneously; Sampling probe 2 is transferred in the detection cup 4 by the dilution blood sample 20ul that takes out mixing in the diluted cup 3 under the assistance of diluter 7 again.Instrument detects platelet Counting quantity behind the blood sample mixing to detecting in the cup after the dilution automatically.Instrument once can be finished one-time detection according to above-mentioned process flow operation, the abandoned reagents after the subsequently automatic eliminating of instrument has detected, and the instrument pipeline washed automatically.Instrument is not to after adding induced polymerization inhibitor blood examination secondary or more times, instrument diluter 10 is collaborative lower valve 12, by drawing induced polymerization inhibitor in the aggregating agent prepared therefrom bottle 11, according to 9: 1 (blood: induced polymerization inhibitor) add induced polymerization inhibitor, instrument is also automatically to the blood sample mixing, constant-temperature incubation, and timing platelet counts the 60-480 time range second continuous detecting blood sample after adding induced polymerization inhibitor, instrument begins counting to blood sample, continuous several times is carried out the platelets analysis counting subsequently, the platelet count value (being no less than 3 times) that instrument will add the blood examination acquisition after the induced polymerization inhibitor automatically averages, and this mean value and the blood platelet reference value that adds the front detection acquisition of induced polymerization inhibitor are relatively calculated acquisition to this blood sample average platelet aggregation rate value.Calculating formula with the method testing result (average platelet aggregation rate) has following A, B dual mode:
A：?
B：?
We have developed a Functional analysys of blood platelet gathering instrument take counting method as principle in the laboratory according to above-mentioned flow scheme design, adopt the utility model instrument to carry out a collection of pattern detection, have obtained satisfied testing result.
Concrete operations are: randomly draw 20 parts of fresh blood samples, every part is divided into four parts of blood samples, and detects and record platelet counts and calculating aggregation rate according to this method flow process is automatic, and gathers each sample checkout discrepancy and carry out the statistical study processing.
Table 1 obtains platelet aggregation rate repeatability with average platelet aggregation rate method detection computations and observes table
* explanation: " A ", " B ", " C ", " D " then represent same sample and are divided into after 4 duplicate samples separately test result in the table, wherein process for ease of data, data behind each time platelet count mean value radix point 4 are given up 5 enter.
Data analysis and conclusion:
Adopt the inventive method that 20 samples are detected for 4 times respectively, cumulative errors are 75.49; The mean value of maximum error value is: 3.77 (%).Illustrate that the platelet aggregation rate result repeatability that adopts the utility model instrument to detect acquisition is better, can meet clinical needs preferably.
Claims (6)
1. a platelet aggregation detects analyser, it is characterized in that: platelet aggregation of the present utility model detect analytical instrument by: sample cup, diluted cup, detection cup, load sample platform, sampling probe, suction sample syringe, induced polymerization inhibitor diluter, dilution syringe form;
Described sample cup is used for storing blood sample;
Described diluted cup is used for once diluting blood sample;
Described detection cup is used for the secondary dilution blood sample and detects blood sample;
Described load sample platform is used for placing sample cup;
Described suction sample syringe is communicated with sampling probe, is used for drawing blood sample to sample cup;
Described induced polymerization inhibitor diluter is communicated with the induced polymerization inhibitor bottle, is used for adding induced polymerization inhibitor to sample cup;
Described dilution syringe is communicated with the dilution bottle, is used for to diluted cup and detects cup adding dilution;
Described sampling probe, suction sample syringe, induced polymerization inhibitor diluter, dilution syringe are moved by Electric Machine Control respectively;
Described sampling probe is communicated with by pipeline and valve inhales sample syringe and dilution syringe;
Described sampling probe with inhale after the sample syringe is communicated with, the blood sample in the sample cup added diluted cup and detect glass;
Described sampling probe is with after the diluter syringe is communicated with, and dilution is added diluted cup and detects in the cup.
2. a kind of platelet aggregation according to claim 1 detects analyser, it is characterized in that: this instrument detects platelet aggregation, it is aggregation rate, the sample cup that only portion need to be equipped with the anticoagulated whole blood blood sample is placed in the sample position of instrument load sample platform, instrument can automatically to sample blending, sampling, detection, be finished detection and report to platelet aggregation.
3. a kind of platelet aggregation according to claim 1 detects analyser, it is characterized in that: being operating as of this instrument: with one fresh anticoagulant whole blood sample cup is housed and is placed on the sample position of this instrument load sample platform, the mixing that instrument just can continue sample automatically, constant temperature and continuous several times detect platelet counts, and according to the platelet aggregation rate that the testing result of blood sample platelet counts is calculated automatically blood sample.
4. a kind of platelet aggregation according to claim 1 detects analyser, and it is characterized in that: the load sample platform of this instrument has automatic continuous function and the automatic continuous function of sample being carried out constant temperature of carrying out mixing of blood sample; The load sample platform can make sample cup stop at vertical position to be convenient to sample sampling and to add induced polymerization inhibitor, also can be by motor-driven load sample platform respectively to left and right the to-and-fro movement that respectively is not more than an angle of 90 degrees degree, so that blood sample obtains continuing mixing in the sample cup.
5. a kind of platelet aggregation according to claim 1 detects analyser, it is characterized in that, this instrument can realize detecting platelet counts in the blood sample according to the principle of electrical impedance or laser.
6. a kind of platelet aggregation according to claim 1 detects analyser, and it is characterized in that: this instrument can be the following A of stating or two kinds of account forms of B to the account form of platelet aggregation, and this result of calculation also can represent with number percent:
A：?
B：?
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220009721 CN202710548U (en) | 2012-01-10 | 2012-01-10 | Detecting and analyzing meter for platelet aggregation function |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201220009721 CN202710548U (en) | 2012-01-10 | 2012-01-10 | Detecting and analyzing meter for platelet aggregation function |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN202710548U true CN202710548U (en) | 2013-01-30 |
Family
ID=47590836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201220009721 Expired - Lifetime CN202710548U (en) | 2012-01-10 | 2012-01-10 | Detecting and analyzing meter for platelet aggregation function |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN202710548U (en) |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104122404A (en) * | 2014-08-01 | 2014-10-29 | 江苏英诺华医疗技术有限公司 | Novel rapid multi-parameter platelet functional analyzer and detection method thereof |
| CN105699299A (en) * | 2016-01-28 | 2016-06-22 | 陈晓乾 | Method and device for measuring content of red blood cells and content of hemachrome |
| CN105699434A (en) * | 2016-01-28 | 2016-06-22 | 陈晓乾 | Method and device for measuring content of blood platelets |
| CN105938096A (en) * | 2015-03-02 | 2016-09-14 | 山东泰利信医疗科技有限公司 | Method for determination of platelet aggregation rate |
| CN106092860A (en) * | 2016-05-29 | 2016-11-09 | 江苏英诺华医疗技术有限公司 | A kind of detection method of platelet activation rate |
| CN106959264A (en) * | 2017-03-16 | 2017-07-18 | 江苏柯伦迪医疗技术有限公司 | A kind of continuous counter method platelet function assay system and method |
| CN108627637A (en) * | 2018-06-04 | 2018-10-09 | 江苏柯伦迪医疗技术有限公司 | A kind of platelet aggregation detecting system and method |
| CN109211729A (en) * | 2018-10-29 | 2019-01-15 | 杨忠思 | A kind of blood stagnation condition checkout gear and method for precisely medical treatment detection |
| CN111474001A (en) * | 2019-01-23 | 2020-07-31 | 贾莉 | A multi-functional sample verifying attachment for blood coagulation routine testing |
-
2012
- 2012-01-10 CN CN 201220009721 patent/CN202710548U/en not_active Expired - Lifetime
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104122404A (en) * | 2014-08-01 | 2014-10-29 | 江苏英诺华医疗技术有限公司 | Novel rapid multi-parameter platelet functional analyzer and detection method thereof |
| CN105938096A (en) * | 2015-03-02 | 2016-09-14 | 山东泰利信医疗科技有限公司 | Method for determination of platelet aggregation rate |
| CN105699299A (en) * | 2016-01-28 | 2016-06-22 | 陈晓乾 | Method and device for measuring content of red blood cells and content of hemachrome |
| CN105699434A (en) * | 2016-01-28 | 2016-06-22 | 陈晓乾 | Method and device for measuring content of blood platelets |
| CN105699299B (en) * | 2016-01-28 | 2018-02-27 | 陈晓乾 | A kind of red blood cell content and hemoglobin assay method and measure device |
| CN105699434B (en) * | 2016-01-28 | 2018-03-23 | 陈晓乾 | A kind of assay method of platelet content and measure device |
| CN106092860A (en) * | 2016-05-29 | 2016-11-09 | 江苏英诺华医疗技术有限公司 | A kind of detection method of platelet activation rate |
| CN106959264A (en) * | 2017-03-16 | 2017-07-18 | 江苏柯伦迪医疗技术有限公司 | A kind of continuous counter method platelet function assay system and method |
| CN108627637A (en) * | 2018-06-04 | 2018-10-09 | 江苏柯伦迪医疗技术有限公司 | A kind of platelet aggregation detecting system and method |
| CN109211729A (en) * | 2018-10-29 | 2019-01-15 | 杨忠思 | A kind of blood stagnation condition checkout gear and method for precisely medical treatment detection |
| CN111474001A (en) * | 2019-01-23 | 2020-07-31 | 贾莉 | A multi-functional sample verifying attachment for blood coagulation routine testing |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN202710548U (en) | Detecting and analyzing meter for platelet aggregation function | |
| CN102253230B (en) | Automatic analyzer and analysis method of blood platelets | |
| CN104165834B (en) | Blood analysis device | |
| CN104122404A (en) | Novel rapid multi-parameter platelet functional analyzer and detection method thereof | |
| EP2921862B1 (en) | Blood testing apparatus and blood testing method | |
| WO2018032718A1 (en) | Blood cell and biochemical assay device, and assay method thereof | |
| CN205656141U (en) | But conventional analytical equipment of simultaneous measurement CRP and blood | |
| CN105334243A (en) | Blood analyzer | |
| CN103163288A (en) | Optimized automation-adaptable platelet aggregation function inspection and analysis method | |
| CN202126438U (en) | Automatic analyzer for platelets | |
| CN206648928U (en) | A kind of multi-parameter blood analyser | |
| CN104990848A (en) | Device and method for detecting micro-particles compatible with process | |
| CN204028091U (en) | A kind of novel Platelet function Analyzer of multiparameter fast | |
| CN209911385U (en) | Blood detection device | |
| CN109211737A (en) | Sample testing apparatus, sample analyser and sample testing method | |
| CN105954239A (en) | Method for detecting platelet aggregation function | |
| CN106168610A (en) | Fluorimetric HPLC measures the method for concentration of Clozapine in blood plasma | |
| CN110678734B (en) | Blood testing method and apparatus | |
| CN205826667U (en) | Disposable blood cell counting and analytic set member and New Blood analyser | |
| CN204789248U (en) | With compatible microparticle detection device of process | |
| CN110871202A (en) | Sampling needle cleaning method and blood cell analyzer | |
| CN103245777A (en) | Novel method for detecting and evaluating blood coagulation function | |
| US9606104B2 (en) | Automated platelet function analyzer and its analytical methods | |
| Dewi et al. | Analysis of Blood Sample Lysis Rate on Hemoglobin Examination Results Using Rayto RT. 7600 Auto Hematology Analyzer | |
| CN116087542A (en) | Sample analyzer and sample detection method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C56 | Change in the name or address of the patentee |
Owner name: JIANGSU SINNOWA MEDICAL SCIENCE + TECHNOLOGY CO., Free format text: FORMER NAME: NANJING SINNOWA MEDICAL SCIENCE + TECHNOLOGY CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Address after: 211135 Nanjing, Jiangning, Qilin street, Po Shan Road, No. 7 Patentee after: SINNOWA MEDICAL SCIENCE & TECHNOLOGY CO., LTD. Address before: 211135 Nanjing, Jiangning, Qilin street, Po Shan Road, No. 7 Patentee before: Nanjing Sinnowa Medical Science & Technology Co., Ltd. |
|
| CX01 | Expiry of patent term |
Granted publication date: 20130130 |
|
| CX01 | Expiry of patent term |