CN108434121B - 一种双层核壳结构分子载体 - Google Patents
一种双层核壳结构分子载体 Download PDFInfo
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- CN108434121B CN108434121B CN201810253388.4A CN201810253388A CN108434121B CN 108434121 B CN108434121 B CN 108434121B CN 201810253388 A CN201810253388 A CN 201810253388A CN 108434121 B CN108434121 B CN 108434121B
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- nanometer rods
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- gdwo
- gadolinium tungstate
- tungstate sodium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/5115—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/14—Peptides, e.g. proteins
- A61K49/16—Antibodies; Immunoglobulins; Fragments thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/18—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
- A61K49/1818—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes particles, e.g. uncoated or non-functionalised microparticles or nanoparticles
- A61K49/1884—Nanotubes, nanorods or nanowires
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/51—Nanocapsules; Nanoparticles
- A61K9/5107—Excipients; Inactive ingredients
- A61K9/513—Organic macromolecular compounds; Dendrimers
- A61K9/5169—Proteins, e.g. albumin, gelatin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
- C01G41/00—Compounds of tungsten
- C01G41/006—Compounds containing, besides tungsten, two or more other elements, with the exception of oxygen or hydrogen
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01P—INDEXING SCHEME RELATING TO STRUCTURAL AND PHYSICAL ASPECTS OF SOLID INORGANIC COMPOUNDS
- C01P2004/00—Particle morphology
- C01P2004/10—Particle morphology extending in one dimension, e.g. needle-like
- C01P2004/16—Nanowires or nanorods, i.e. solid nanofibres with two nearly equal dimensions between 1-100 nanometer
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Nanotechnology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Optics & Photonics (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201810253388.4A CN108434121B (zh) | 2018-03-26 | 2018-03-26 | 一种双层核壳结构分子载体 |
Applications Claiming Priority (1)
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CN201810253388.4A CN108434121B (zh) | 2018-03-26 | 2018-03-26 | 一种双层核壳结构分子载体 |
Publications (2)
Publication Number | Publication Date |
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CN108434121A CN108434121A (zh) | 2018-08-24 |
CN108434121B true CN108434121B (zh) | 2019-04-09 |
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CN201810253388.4A Active CN108434121B (zh) | 2018-03-26 | 2018-03-26 | 一种双层核壳结构分子载体 |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN109675034B (zh) * | 2019-02-22 | 2021-04-30 | 重庆医科大学 | 一种多模态造影剂及其用途 |
CN110052602B (zh) * | 2019-05-13 | 2021-04-13 | 洛阳理工学院 | 金纳米棒/银/二氧化钛核壳纳米复合结构及其制备方法 |
CN114309580A (zh) * | 2021-12-30 | 2022-04-12 | 杭州电子科技大学 | 一种球形金纳米棒自组装超级粒子的制备方法 |
CN114873644A (zh) * | 2022-05-10 | 2022-08-09 | 安徽农业大学 | 一种用于分子检测的分子载体的制备方法 |
Family Cites Families (1)
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CN102199312B (zh) * | 2011-03-07 | 2012-07-25 | 青岛大学 | 一种具有缓释功能的介孔氧化硅微粒复合载体及其制备方法和应用 |
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2018
- 2018-03-26 CN CN201810253388.4A patent/CN108434121B/zh active Active
Non-Patent Citations (3)
Title |
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Engineering of inorganic nanoparticles as magnetic resonance imaging contrast agents;Dalong Ni等;《Chemical Society Reviews》;20171026;7438-7468 |
Oxygen Vacancy Enables Markedly Enhanced Magnetic Resonance Imaging-Guided Photothermal Therapy of a Gd3+-Doped Contrast Agent;Dalong Ni等;《ACS Nano》;20170321;4256-4264 |
用于医学磁共振影像的稀土上转换发光纳米材料;孟宪福等;《发光学报》;20180131;第39卷(第1期);69-91 |
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CN108434121A (zh) | 2018-08-24 |
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Inventor after: Fang Xiangming Inventor after: Bu Wenbo Inventor after: Chen Hongwei Inventor after: Ni Dalong Inventor after: Wu Wanlu Inventor after: Zou Jian Inventor after: Yao Zhenwei Inventor after: Hu Xiaoyun Inventor after: Hu Chunhong Inventor before: Fang Xiangming Inventor before: Bu Wenbo Inventor before: Chen Hongwei Inventor before: Ni Dalong Inventor before: Wu Wanlu Inventor before: Zou Jian Inventor before: Yao Zhenwei Inventor before: Hu Xiaoyun Inventor before: Hu Chunhong |