CN108392569A - A kind of herbal medicine micro mist and preparation method thereof for treating pregnant sow physiological constipation - Google Patents

A kind of herbal medicine micro mist and preparation method thereof for treating pregnant sow physiological constipation Download PDF

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Publication number
CN108392569A
CN108392569A CN201810580078.3A CN201810580078A CN108392569A CN 108392569 A CN108392569 A CN 108392569A CN 201810580078 A CN201810580078 A CN 201810580078A CN 108392569 A CN108392569 A CN 108392569A
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constipation
radix
micro mist
herbal medicine
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孙国平
陈培源
刘俊
吴正荣
张吉鹍
马宏星
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Hubei Boda Biological Co Ltd
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Hubei Boda Biological Co Ltd
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Abstract

The invention discloses a kind of herbal medicine micro mists for treating pregnant sow physiological constipation, by weight, including the following raw material component:18~22 parts of radix rehmanniae preparata, 10~15 parts of Radix Angelicae Sinensis, 8~15 parts of Radix Astragali, 6~10 parts of Radix Codonopsis, 6~10 parts of Rhizoma Atractylodis Macrocephalae, 6~10 parts of asparagus fern, 6~10 parts of Radix Ophiopogonis, 6~10 parts of snakegourd, 6~10 parts of pockmarks benevolence, 6~10 parts of Herba Cistanches, 6~10 parts of root of Aucklandia lappa Decne, 6~10 parts of dried orange peel, 6~10 parts of Fructus Aurantii;The invention also discloses the preparation methods of the herbal medicine micro mist;The herbal medicine micro mist is effective combination of Traditional Chinese Medicine diagnosis and treatment based on an overall analysis of the illness and the patient's condition theory and modern medicines preparation process, for gestational period sow, the constipation because caused by easily occurring blood deficiency and depleted fluid, depression and stagnation of QI for physiologic factor has good therapeutic effect, and illeffects will not be generated to sow and fetus, efficiently solve the problems, such as that currently common anti-constipation drug is poor to pregnant domestic animal effect, toxic side effect is big.

Description

A kind of herbal medicine micro mist and its preparation for treating pregnant sow physiological constipation Method
Technical field
The present invention relates to animal veterinary drug technical fields more particularly to a kind of for treating in pregnant sow physiological constipation Veterinary drug micro mist.
Background technology
Pregnant sow physiological constipation is a kind of very universal phenomenon present in large-scale pig farm sow group, hair Raw rate is about 30%, and selected swine farms are up to 50%, is brought to swinery health, the performance of production performance and swinery management prodigious Negative effect.Pregnant sow causes intestinal smooth convergent force to weaken due to the effect of progestational hormone, the uterus compressing expanded in addition Intestinal tube inhibits intestinal contents movement, excrement to accumulate overlong time in intestines, and moisture is gradually absorbed, and dry feces are made, this existing As for physiological constipation, at present in production for this kind of constipation mainly based on the class chemicals that come down in torrents, but effect is undesirable, and And toxic action easily is generated to sow and fetus.
Traditional Chinese medicine thinks that gradually length can influence mechanism of qi liter to the decline of sow gestation phase the moon blood with nourishing the fetus, hyperactivity of yang due to yin deficiency, while carcass Drop, therefore cause enteron aisle transmission powerless, large intestine loses it and moistens and constipation.Therefore constipation in pregnancy treatment is when with nourishing yin and nourishing blood ease constipation, row Based on gas defaecation, the class drug that comes down in torrents under bitter cold is led to absurd should not be thrown.
Micro mist technique refers to overcoming solid interior cohesiveness to be allowed to broken using machinery or hydrokinetic method, thus will The material particles of 3mm or more are crushed to the operating technology of 300~500 mesh, modern high-new to adapt to after being the 1970s The development of technology and a kind of materiel machining new and high technology generated.Micro mist has the unexistent special physico-chemical property of general particle, Such as good dissolubility, dispersibility, adsorptivity, chemical reactivity.
Therefore, pregnant sow constipation problem can be effectively improved but and will not be damaged to sow by how preparing one kind Herbal medicine micro mist become urgent problem to be solved.
Invention content
It is an object of the invention to overcome the defect of the prior art, provide a kind of for treating pregnant sow physiological just Secret herbal medicine micro mist and preparation method thereof is effective knot of Traditional Chinese Medicine diagnosis and treatment based on an overall analysis of the illness and the patient's condition theory and modern medicines preparation process It closes, for gestational period sow, the constipation because caused by easily occurring blood deficiency and depleted fluid, depression and stagnation of QI for physiologic factor has good treatment Effect, and illeffects will not be generated to sow and fetus, currently common anti-constipation drug is efficiently solved to pregnant domestic animal effect The big problem of difference, toxic side effect.
The invention is realized in this way:
It is an object of the present invention to provide a kind of herbal medicine micro mists for treating pregnant sow physiological constipation, by weight Measure part meter, including the following raw material component:It is 18~22 parts of radix rehmanniae preparata, 10~15 parts of Radix Angelicae Sinensis, 8~15 parts of Radix Astragali, 6~10 parts of Radix Codonopsis, white 6~10 parts of art, 6~10 parts of asparagus fern, 6~10 parts of Radix Ophiopogonis, 6~10 parts of snakegourd, 6~10 parts of pockmarks benevolence, 6~10 parts of Herba Cistanches, wood 6~10 parts fragrant, 6~10 parts of dried orange peel, 6~10 parts of Fructus Aurantii.
The second object of the present invention is to provide a kind of for treating the herbal medicine micro mist of pregnant sow physiological constipation Preparation method, described method includes following steps:
Step 1:Respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis and Fructus Aurantii co-grinding, by Radix Angelicae Sinensis, Radix Astragali, party Ginseng, Rhizoma Atractylodis Macrocephalae, pockmarks benevolence, Herba Cistanches, root of Aucklandia lappa Decne individually crush, and coarse powder is obtained after being sieved respectively;
Step 2:The coarse powder for each component that step 1 obtains is uniformly mixed by the proportioning, obtains the material of mixing;
Step 3, by material that step 2 obtains injection micronizer crush grain size be the micro mist of 500 mesh to obtain the final product.
Activity is as follows the effect of each primary raw material medicine in the present invention:
1, radix rehmanniae preparata:Also known as prepared rehmannia root or throw oneself on the ground, belong to goatweed, be a kind of first-class Chinese medicine, there is enriching yin work(of enriching blood Effect, radix rehmanniae preparata is sweet in flavor, mild-natured and enter blood system, function nourishing yin and supplementing blood, enriching essence and nourishing marrow.Control that deficiency of Yin blood is few, brains it is hollow waist and knee extremely Impotence is weak, Cough osteopyrexia, and seminal emission, uterine bleeding, irregular menstruation is quenched one's thirst, number of urinating, deaf, blurred vision, palpitation and insomnia, forgetful, night sweat etc..
2, Radix Angelicae Sinensis:Work(is being enriched blood and blood, and irregular menstruation, dizziness due to deficiency of blood, the swollen equal diseases of sore are cured mainly;Chinese medicine thinks that cloudy blood is same Source, blood-nourishing, enriching yin should synchronize progress, and Radix Angelicae Sinensis is arranged in pairs or groups with radix rehmanniae preparata, there is two big benefits, first, achieve the purpose that yin-nourishing by enriching blood, Enriching yin is one of the effective ways enriched blood again.Second is that Radix Angelicae Sinensis itself has extraordinary blood circulation-promoting functions, mend without stagnant, radix rehmanniae preparata and works as Return be combined in one piece with outclass a prescription use.
3, Radix Astragali:There are enhancing body's immunity, liver protection, diuresis, anti-aging, resisting stress, decompression and wide antibacterial Effect.Belong to warm nature, is common Chinese medicine simply.Its main pharmacological is " invigorating qi for consolidating superficies ", and invigorating the blood is to push qi and blood Operation, can " Li Shui ", can also " promoting pus discharge and tissue regeneration ".
4, Radix Codonopsis:Strengthening the spleen and stomach, blood-enrich;The primary efficacy of Radix Codonopsis is tonifying Qi, lays particular emphasis on the people of deficiency of spleen-QI and stomach-QI, four limbs without Power, loss of appetite, loose watery stool etc., Radix Codonopsis tonifying Qi and can blood-nourishing, this is its a big feature, Radix Codonopsis can make erythremia, Hemoglobin increases, so anaemia patients Radix Codonopsis is very helpful.The leucocyte caused by chemotherapy and radiotherapy declines, clothes Also there is the effect for promoting leucocyte to go up with Radix Codonopsis;Radix Codonopsis and Rhizoma Atractylodis Macrocephalae compatibility, air making-up and spleen enlivening.
5, Rhizoma Atractylodis Macrocephalae:Rhizoma Atractylodis Macrocephalae has the effect of strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, tocolysis.For spleen eating less, abdominal distension is let out It rushes down, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration, fetal irritability.
6, asparagus fern:It is cold in nature, sweet in flavor, slight bitter;(1) nourishing Yin and promoting production of body fluid:Treat fever due to yin deficiency, dryness of the lung dry cough, cough due to consumptive disease, Tianjin wound It is thirsty to have good effect;(2) moistening lung clears away heart-fire:Vexed insomnia, abscess of throat are treated, Heat Diabetes has fine curative effect;(3) It relaxes bowel:The internal thermally-induced dry and hard excrement of asparagus fern, dry constipation of intestines can play the role of relaxing bowel, and especially the deficiency of Yin causes Effect more.
7, Radix Ophiopogonis;The small root tuber of Radix Ophiopogonis is Chinese medicine, there is the benefits of quench one's thirst of promoting the production of body fluid, moisten the lung and relieve the cough.
8, snakegourd:Alias:Snakegourd Fruit, sugared Snakegourd Fruit, beach wormwood melon, cure mainly:Clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation.For lung heat Cough, the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, lung carbuncle, acute appendicitis swelling and pain, constipation.
9, pockmarks benevolence:It can relax bowel, nourish qi-restoratives, be suitable for caused by pathogenic heat damaging YIN or ferritic hyperactivity of fire, intestine-dryness due to consumption of fluid Constipation, abdominal fullness and distention, nausea be intended to vomit.
10, Herba Cistanches:Kidney-replenishing, relaxes bowel at benefiting essence-blood.
11, root of Aucklandia lappa Decne:Cure mainly promoting qi circulation and relieving pain, reinforcing spleen to promote digestion.
12, dried orange peel:Acrid flavour, hardship, it is warm-natured;Returns spleen, stomach, lung channel;With qi-regulating in, eliminating dampness and eliminating phlegm, the work(of sharp water defaecation Effect;Incoordination between the spleen and the stomach, abdominal distention is cured mainly, do not feel like eating vomits hiccup;Oedema, difficult urination, constipation can effectively be solved; Acute mastitis mange, middle ichthyophagy crab poison, wine poison etc..
13, Fructus Aurantii:Property it is bitter, pungent, sour, warm, there is the effect of regulating the flow of QI to ease the stomach, row stagnant dissipate-swelling, cure mainly the chest side of body stagnation of the circulation of vital energy, turgor pain Bitterly, accumulation of food in the stomach and intes tine due to indigestion stops in phlegm and retained fluid;Gastroptosis, rectal prolapse, the illnesss such as sub-official prolapses;With the compatibilities such as Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, to replenish qi to invigorate the spleen, Resolving and invigoration therapies being applied simultaneously.
Compared with prior art, the invention has the advantages that and effect:
1, prescription is exquisite, and treatment anti-constipation effect is good:Radix rehmanniae preparata in the prescription of the present invention, when being classified as nourishing yin and supplementing blood key medicine, be monarch Medicine;Spleen is ying, wei, qi, xue the source of vital function, therefore Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae are invigorated the spleen and benefited qi with green blood in side, and blood Sheng Zejin profits, are ministerial drug; Asparagus fern, Radix Ophiopogonis nourishing Yin and moistening dryness, open kidney water, support lung stomach-Yin Tianjin it is dry with ease constipation, share the work(to help radix rehmanniae preparata, Radix Angelicae Sinensis to nourish Tianjin blood, also For ministerial drug;Snakegourd moisturizes out that knot, pockmarks benevolence benefit are cloudy to increase liquid, Herba Cistanches warm kidney ease constipation, and three medicines can all help that help the monarch and his subjects logical to increase ease constipation Just work(, and the how sweet temperature of nature and flavor, in case all cold and cool product impairing the spleen and stomach, are adjutant;Root of Aucklandia lappa Decne, dried orange peel are amusing and stomach, during Fructus Aurantii is wide Relieving stagnant Qi, and qi-benefiting and spleen-strengthening drug, nourishing yin and nourishing blood medicine compatibility make benefit without stagnant, grow and oiliness, this three medicine shares, altogether to make medicine.All medicines The benefits of sharing, playing nourishing yin and nourishing blood, ease constipation of promoting the production of body fluid, promoting the circulation of qi defaecation altogether, therefore it is good to treat anti-constipation effect;
2, safe, it has no toxic side effect to sow and fetal well-being:According to theory of traditional Chinese medical science to pregnant sow physiological just It is secret carry out it is dialectical treats, prescription medicine nourishing Yin and moistening dryness, promoting the circulation of qi defaecation, and mend without stagnant are grown and oiliness, are pure Chinese medicinal preparation, It is safe;Blood cytology and biochemical index are normal, safely controllable on pregnant sow influence without exception;
3, preparation method is excellent:By the viscous materials such as radix rehmanniae preparata, asparagus fern, Radix Ophiopogonis respectively with the brittle materials string such as snakegourd, dried orange peel, Fructus Aurantii Feed powder is broken, works well;Using current state-of-the-art micronizer third generation vibromill (WZJ-100A types), in ethylene glycol system By crushing material to 500 mesh under cool condition, the operating time is short, and product characteristics are good, and it is broken that micromill process realizes Chinese medicine cell Wall crushes, and substantially increases the bioavilability of Chinese medicine;
4, easy to use:500 mesh grade micro-powder of Chinese herbs can uniformly, stable dispersion in water, can be straight in breeding production It connects drinking-water to use, not interfered by the feed intake decline of prevention of sow constipation phase;Powder size small (25 μm) can be directly appended to drink water Middle use changes the drawbacks of necessary spice of general drug adds, is not influenced by the decline of constipation phase feed intake, be easy to raising pigs It is promoted in production.
Specific implementation mode
Embodiment 1
1, by weight, the herbal medicine micro mist for treating pregnant sow physiological constipation of the present embodiment is by such as the following group It is grouped as:
18 parts of radix rehmanniae preparata, 10 parts of Radix Angelicae Sinensis, 10 parts of Radix Astragali, 8 parts of Radix Codonopsis, 8 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of asparagus fern, 6 parts of Radix Ophiopogonis, 8 parts of snakegourd, fiber crops 10 parts of sub- benevolence, 10 parts of Herba Cistanches, 10 parts of root of Aucklandia lappa Decne, 10 parts of dried orange peel, 10 parts of Fructus Aurantii.
2, the preparation method of the herbal medicine micro mist for treating pregnant sow physiological constipation includes the following steps:
Step 1, coarse powder:Using Universalpulverizer (10 DEG C of water cooling) respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis with Fructus Aurantii co-grinding, other medicinal materials individually crush, and cross 60 mesh sieve;
Step 2, mixing:After the bulk pharmaceutical chemicals after above-mentioned coarse powder tentatively mixing, then it is placed in V-type batch mixer and continuously mixes 30min is uniformly mixed, the consistent mixed powder of color and luster;
Step 3, micro mist:The fine powder material that step 2 is obtained vibration type ultramicro disintegrator (ethylene glycol freezes -8 DEG C) powder It is broken into 500 mesh micro mists.
Embodiment 2
1, by weight, the herbal medicine micro mist for treating pregnant sow physiological constipation of the present embodiment is by such as the following group It is grouped as:
18 parts of radix rehmanniae preparata, 15 parts of Radix Angelicae Sinensis, 10 parts of Radix Astragali, 8 parts of Radix Codonopsis, 8 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of asparagus fern, 6 parts of Radix Ophiopogonis, 8 parts of snakegourd, fiber crops 10 parts of sub- benevolence, 8 parts of Herba Cistanches, 10 parts of root of Aucklandia lappa Decne, 10 parts of dried orange peel, 10 parts of Fructus Aurantii.
2, the preparation method of the herbal medicine micro mist for treating pregnant sow physiological constipation includes the following steps:
Step 1, coarse powder:Using Universalpulverizer (10 DEG C of water cooling) respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis with Fructus Aurantii co-grinding, other medicinal materials individually crush, and cross 60 mesh sieve;
Step 2, mixing:After the bulk pharmaceutical chemicals after above-mentioned coarse powder tentatively mixing, then it is placed in V-type batch mixer and continuously mixes 30min is uniformly mixed, the consistent mixed powder of color and luster;
Step 3, micro mist:The fine powder material that step 2 is obtained vibration type ultramicro disintegrator (ethylene glycol freezes -8 DEG C) powder It is broken into 500 mesh micro mists.
Embodiment 3
1, by weight, the herbal medicine micro mist for treating pregnant sow physiological constipation of the present embodiment is by such as the following group It is grouped as:
20 parts of radix rehmanniae preparata, 12 parts of Radix Angelicae Sinensis, 8 parts of Radix Astragali, 8 parts of Radix Codonopsis, 6 parts of Rhizoma Atractylodis Macrocephalae, 8 parts of asparagus fern, 8 parts of Radix Ophiopogonis, 8 parts of snakegourd, fiber crops 6 parts of sub- benevolence, 8 parts of Herba Cistanches, 6 parts of root of Aucklandia lappa Decne, 8 parts of dried orange peel, 8 parts of Fructus Aurantii.
2, the preparation method of the herbal medicine micro mist for treating pregnant sow physiological constipation includes the following steps:
Step 1, coarse powder:Using Universalpulverizer (10 DEG C of water cooling) respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis with Fructus Aurantii co-grinding, other medicinal materials individually crush, and cross 60 mesh sieve;
Step 2, mixing:After the bulk pharmaceutical chemicals after above-mentioned coarse powder tentatively mixing, then it is placed in V-type batch mixer and continuously mixes 30min is uniformly mixed, the consistent mixed powder of color and luster;
Step 3, micro mist:The fine powder material that step 2 is obtained vibration type ultramicro disintegrator (ethylene glycol freezes -8 DEG C) powder It is broken into 500 mesh micro mists.
Embodiment 4
1, by weight, the herbal medicine micro mist for treating pregnant sow physiological constipation of the present embodiment is by such as the following group It is grouped as:
22 parts of radix rehmanniae preparata, 15 parts of Radix Angelicae Sinensis, 8 parts of Radix Astragali, 8 parts of Radix Codonopsis, 6 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of asparagus fern, 6 parts of Radix Ophiopogonis, 8 parts of snakegourd, fiber crops 6 parts of sub- benevolence, 8 parts of Herba Cistanches, 6 parts of root of Aucklandia lappa Decne, 8 parts of dried orange peel, 8 parts of Fructus Aurantii.
2, the preparation method of the herbal medicine micro mist for treating pregnant sow physiological constipation includes the following steps:
Step 1, coarse powder:Using Universalpulverizer (10 DEG C of water cooling) respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis with Fructus Aurantii co-grinding, other medicinal materials individually crush, and cross 60 mesh sieve;
Step 2, mixing:After the bulk pharmaceutical chemicals after above-mentioned coarse powder tentatively mixing, then it is placed in V-type batch mixer and continuously mixes 30min is uniformly mixed, the consistent mixed powder of color and luster;
Step 3, micro mist:The fine powder material that step 2 is obtained vibration type ultramicro disintegrator (ethylene glycol freezes -8 DEG C) powder It is broken into 500 mesh micro mists.
Embodiment 5
1, by weight, the herbal medicine micro mist for treating pregnant sow physiological constipation of the present embodiment is by such as the following group It is grouped as:
18 parts of radix rehmanniae preparata, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Astragali, 15 parts of Radix Codonopsis, 10 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of asparagus fern, 6 parts of Radix Ophiopogonis, 8 parts of snakegourd, 10 parts of pockmarks benevolence, 8 parts of Herba Cistanches, 6 parts of root of Aucklandia lappa Decne, 6 parts of dried orange peel, 6 parts of Fructus Aurantii.
2, the preparation method of the herbal medicine micro mist for treating pregnant sow physiological constipation includes the following steps:
Step 1, coarse powder:Using Universalpulverizer (10 DEG C of water cooling) respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis with Fructus Aurantii co-grinding, other medicinal materials individually crush, and cross 60 mesh sieve;
Step 2, mixing:After the bulk pharmaceutical chemicals after above-mentioned coarse powder tentatively mixing, then it is placed in V-type batch mixer and continuously mixes 30min is uniformly mixed, the consistent mixed powder of color and luster;
Step 3, micro mist:The fine powder material that step 2 is obtained vibration type ultramicro disintegrator (ethylene glycol freezes -8 DEG C) powder It is broken into 500 mesh micro mists.
Embodiment 6
1, by weight, the herbal medicine micro mist for treating pregnant sow physiological constipation of the present embodiment is by such as the following group It is grouped as:
18 parts of radix rehmanniae preparata, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Astragali, 15 parts of Radix Codonopsis, 10 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of asparagus fern, 6 parts of Radix Ophiopogonis, 8 parts of snakegourd, 10 parts of pockmarks benevolence, 8 parts of Herba Cistanches, 10 parts of root of Aucklandia lappa Decne, 10 parts of dried orange peel, 10 parts of Fructus Aurantii.
2, the preparation method of the herbal medicine micro mist for treating pregnant sow physiological constipation includes the following steps:
Step 1, coarse powder:Using Universalpulverizer (10 DEG C of water cooling) respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis with Fructus Aurantii co-grinding, other medicinal materials individually crush, and cross 60 mesh sieve;
Step 2, mixing:After the bulk pharmaceutical chemicals after above-mentioned coarse powder tentatively mixing, then it is placed in V-type batch mixer and continuously mixes 30min is uniformly mixed, the consistent mixed powder of color and luster;
Step 3, micro mist:The fine powder material that step 2 is obtained vibration type ultramicro disintegrator (ethylene glycol freezes -8 DEG C) powder It is broken into 500 mesh micro mists.
The safety of experimental example target animals and evaluation of clinical curative effect
1, this experiment is designed using randomized block experiment, and in Hubei, farm is tested, and selection has in various degree just Pregnant 60-65 days average parity of secret generation are that 2 tires are grown up binary sow 80, are raised 3 days, every morning 8:00~9: 00, afternoon 1:30-2:00 observation sow defecation situation, scores to every sow according to table 1.80 pregnant sows are divided into 8 groups so that the sum of constipation scoring of every group of 10 pigs is equal, and grouping raising carries out drug test after 3 days, and first group is not added medicine Object, second group is given magnesium sulfate processing, remaining six groups are added drug obtained by Examples 1 to 6 respectively, and continuous use records after 10 days Every group of constipation improves degree, and carries out blood cytology and biochemical detection to each sow acquisition blood sample, the results are shown in Table 2,3. Each sows farrowing after about 40 days, record each group sow litter quantity, nascent counterpoise and diarrhea rate.
2, as shown in table 1, it is constipation degree standards of grading;
1 constipation degree standards of grading of table
3, the anti-anti-constipation effect of drug and production performance such as table 2, are found out by table, addition 1- of embodiment of the present invention embodiments 6 Drug after pregnant sow constipation rate have 25% or more rate of descent, the not adder constipation of blank group aggravates 43.7%, and And Examples 1 to 6 effect is superior to magnesium sulfate group (class of coming down in torrents chemicals magnesium sulfate) (P<0.01), 5 best results of embodiment. In comparison, farrowing quantity increased each group institute number pigs born amount with birth weight after adding drug of the present invention, and diarrhea rate It reduces, (P with obvious effects<0.01),;
2 drug of table compares each group pregnant sow treatment anti-constipation effect with production performance
4, the detection numerical value of target animals safety indexes as shown in Table 3, between 8 groups blood cytology and biochemical index without Notable difference (P>0.05), and illustrate drug of the present invention to pregnant sow influence without exception, it is safely controllable.
Influence of 3 drug of table to each group pregnant sow blood cytology and biochemical index
In conclusion the present invention provide it is a kind of for treat the herbal medicine micro mist of pregnant sow physiological constipation to be in tradition The effective combination for curing diagnosis and treatment based on an overall analysis of the illness and the patient's condition theory and modern medicines preparation process, for gestational period sow because the deficiency of blood easily occurs for physiologic factor Constipation caused by body fluid deficiency, depression and stagnation of QI has good therapeutic effect, is significantly increased with birth weight to farrowing quantity, and And illeffects will not be generated to sow and fetus, it is poor to pregnant domestic animal effect, malicious secondary to efficiently solve currently common anti-constipation drug Act on big problem;Micromill process realizes the crushing of Chinese medicine breaking-wall cell, substantially increases the bioavilability of Chinese medicine, Powder size small (25 μm) can be directly appended to use in drinking-water, change the drawbacks of necessary spice of general drug adds, no It is influenced by the decline of constipation phase feed intake, is easy to promote in pig production.
It is described be only presently preferred embodiments of the present invention, be not intended to limit the invention, it is all the present invention spirit and Within principle, any modification, equivalent replacement, improvement and so on should all include within protection scope of the present invention.

Claims (7)

1. a kind of herbal medicine micro mist for treating pregnant sow physiological constipation, which is characterized in that by weight, including such as Lower raw material components:18~22 parts of radix rehmanniae preparata, 10~15 parts of Radix Angelicae Sinensis, 8~15 parts of Radix Astragali, 6~10 parts of Radix Codonopsis, 6~10 parts of Rhizoma Atractylodis Macrocephalae, asparagus fern 6~10 parts, 6~10 parts of Radix Ophiopogonis, 6~10 parts of snakegourd, 6~10 parts of pockmarks benevolence, 6~10 parts of Herba Cistanches, 6~10 parts of root of Aucklandia lappa Decne, dried orange peel 6 ~10 parts, 6~10 parts of Fructus Aurantii.
2. the herbal medicine micro mist as described in claim 1 for treating pregnant sow physiological constipation, which is characterized in that by weight Measure part meter, including the following raw material component:18 parts of radix rehmanniae preparata, 15 parts of Radix Angelicae Sinensis, 15 parts of Radix Astragali, 15 parts of Radix Codonopsis, 10 parts of Rhizoma Atractylodis Macrocephalae, 6 parts of asparagus fern, 6 parts of Radix Ophiopogonis, 8 parts of snakegourd, 10 parts of pockmarks benevolence, 8 parts of Herba Cistanches, 6 parts of root of Aucklandia lappa Decne, 6 parts of dried orange peel, 6 parts of Fructus Aurantii.
3. a kind of preparation of herbal medicine micro mist for treating pregnant sow physiological constipation as described in claim 1-2 is any Method, which is characterized in that described method includes following steps:
Step 1:Respectively by radix rehmanniae preparata and snakegourd, asparagus fern and dried orange peel, Radix Ophiopogonis and Fructus Aurantii co-grinding, by Radix Angelicae Sinensis, Radix Astragali, Radix Codonopsis, white Art, pockmarks benevolence, Herba Cistanches, root of Aucklandia lappa Decne individually crush, and coarse powder is obtained after being sieved respectively;
Step 2:The coarse powder for each component that step 1 obtains is uniformly mixed by any proportionings of claim 1-2, is mixed Even material;
Step 3, by material that step 2 obtains injection micronizer crush grain size be the micro mist of 500 mesh to obtain the final product.
4. the preparation method as claimed in claim 3 for treating the herbal medicine micro mist of pregnant sow physiological constipation, special Sign is, the Universalpulverizer that water cooling is 10 DEG C when being crushed in the step 1.
5. the preparation method as claimed in claim 3 for treating the herbal medicine micro mist of pregnant sow physiological constipation, special Sign is, is sieved with 60 mesh when being sieved described in the step 1.
6. the preparation method as claimed in claim 3 for treating the herbal medicine micro mist of pregnant sow physiological constipation, special Sign is that the specific method mixed in the step 2 is:After the tentatively mixing of the coarse powder for each component that first step 1 is obtained, then set 30min is continuously mixed in V-type batch mixer.
7. the preparation method as claimed in claim 3 for treating the herbal medicine micro mist of pregnant sow physiological constipation, special Sign is, spent glycol refrigeration is -8 DEG C of vibration type ultramicro disintegrator when being crushed in the step 3.
CN201810580078.3A 2018-06-07 2018-06-07 A kind of herbal medicine micro mist and preparation method thereof for treating pregnant sow physiological constipation Pending CN108392569A (en)

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