CN110547369A

CN110547369A - Pharmaceutical composition and feed suitable for sows in gestation period

Info

Publication number: CN110547369A
Application number: CN201910873654.8A
Authority: CN
Inventors: 宗彦鲜; 吴仙花; 赵元; 许迟; 秦小亮; 靳建学
Original assignee: Ningxia Dabei Agricultural Science And Technology Industrial Co Ltd
Current assignee: Ningxia Dabei Agricultural Science And Technology Industrial Co Ltd
Priority date: 2019-09-17
Filing date: 2019-09-17
Publication date: 2019-12-10

Abstract

The invention discloses a pharmaceutical composition and feed suitable for sows in gestation period, which comprises the following components in parts by weight: 13-14 parts of stomach calming powder, 16-18 parts of glucose powder, 0.3-0.5 part of coptis detoxifying powder, 1-1.5 parts of astragalus polysaccharide powder, 1-1.2 parts of Jinweita, 1-1.2 parts of licorice particles, 2.5-2.8 parts of magnesium sulfate, 0.4-0.5 part of sodium selenite, 1-1.5 parts of body resistance strengthening powder, 1-1.4 parts of wrinkled gianthyssop vital energy strengthening powder, 0.6-1 part of doxycycline, 0.4-0.6 part of tiamulin and 1 part of enzymic prebiotics. It has effects of regulating physiological function and metabolism of sow, regulating intestinal tract, promoting absorption, enhancing pig immunity and resistance, and improving production performance; reducing constipation, dystocia, postpartum anorexia, postpartum agalactia, postpartum piglet maternal diarrhea and the like caused by insufficient sow movement, single feed, poor management and the like, prolonging the healthy production birth times and reducing the elimination rate.

Description

Pharmaceutical composition and feed suitable for sows in gestation period

Technical Field

The invention relates to the technical field of sow breeding, in particular to a pharmaceutical composition and feed suitable for health care of sows in gestation period.

Background

The core of the pig farm is sow, piglet, high productivity and high benefit. If the resistance of the sow is weak and the sow is easy to be infected with diseases, some diseases can be transmitted through the mother and the son, so that the piglets are also infected with diseases. The sow is indigestible and easy to constipation, and toxin generated by metabolism is reabsorbed by the body, so that a series of diseases are generated in the sow, the health of the sow and a fetus is seriously damaged, and the sow is difficult to produce and the number of stillborn fetus is increased in serious cases.

At present, due to intensive development of pig raising, feed daily ration is simplified seriously, corn-soybean meal type is mainly used, the utilization rate of coarse cereals is low, intensive management, limited feeding, high standard, labor intensity reduction and benefit improvement are achieved, sufficient field sports are not available, sows do not move enough, and a series of symptoms such as metabolic disorder, toxin accumulation and constipation of the sows are caused by uncoordinated addition of feed nutrition, vitamins, minerals and the like for long-term use, so that the healthy development of a pig herd is not facilitated.

In view of this, the invention is particularly proposed.

Disclosure of Invention

The invention aims to provide a pharmaceutical composition and a feed suitable for the health care of sows in the gestation period so as to improve the problems.

The invention is realized by the following steps:

In a first aspect, the embodiments of the present invention provide a pharmaceutical composition for pregnant sows, comprising, in parts by weight per thousand: 13-14 parts of stomach calming powder, 16-18 parts of glucose powder, 0.3-0.5 part of coptis detoxifying powder, 1-1.5 parts of astragalus polysaccharide powder, 1-1.2 parts of Jinweita, 1-1.2 parts of licorice particles, 2.5-2.8 parts of magnesium sulfate, 0.4-0.5 part of sodium selenite, 1-1.5 parts of body resistance strengthening powder, 1-1.4 parts of wrinkled gianthyssop vital energy strengthening powder, 0.6-1 part of doxycycline, 0.4-0.6 part of tiamulin and 1 part of enzymic prebiotics.

The medicine combination health-care logic of the invention is as follows: strengthening the stomach and promoting digestion (incompatibility during pregnancy), clearing and expelling toxin (clearing intestinal tract rubbish), clearing heat and cooling blood (clearing toxin at night), regulating metabolism of an organism (digging and recovering normal physiological functions of the organism), improving immunity and resistance of a pig, promoting growth, preventing (clearing heat and detoxicating, preventing heatstroke and reducing temperature), improving production performance of sows (advancing health), and treating diseases (clearing lung and relieving cough). Meanwhile, all the medicines in the prescription have mutual cooperation, so that the health recovery of the body is enhanced, the original physiological function of the sow is dug out, the specific immune defense mechanism of the sow instinct is improved, the purpose of pig group health is achieved, the potential of the sow is dug, the health level is improved, and the production benefit is improved.

The medicine composition of the invention has the following medication thought: stomach calming powder, stomach invigorating and digestion promoting, magnesium sulfate, toxin expelling, coptis chinensis, toxin removing, heat clearing, blood cooling and dysentery stopping, liquorice granules, glucose powder, enzyme prebiotics or yeast culture for regulating intestinal flora and regulating body metabolism, astragalus polysaccharide powder for improving swine immunity and resistance, Jinweita such as lingqi Jinweita for supplementing the nutritional requirements of trace elements of bodies, wrinkled gianthyssop vital qi strengthening powder for heat clearing, toxin removing, heatstroke preventing and cooling, sodium selenite, body resistance strengthening powder for improving the production performance of sows, tilmicosin or tiamulin for clearing away the lung-heat and relieving cough, and the health degree of sows is improved.

In a second aspect, the embodiment of the invention provides a use method of a pharmaceutical composition suitable for pregnant sows, which comprises the steps of feeding the pharmaceutical composition and the pregnant sows in a mixed feed mixing manner according to the weight ratio of X/1000, wherein X is the sum of the weight parts of the pharmaceutical composition; the frequency and the time interval of use are 20-30 days, the continuous medicine mixing and feeding is carried out for 7-10 days for 2-3 times, and the time can be reduced to two months; the feeding is limited for 0.5-1 day before the implementation, no feeding is needed during the feeding limiting period, sufficient and clean drinking water is supplied, the sanitation and the dryness of the colony are kept, and the colony is firm; the feeding is limited for 2-3 days during the implementation period, the feeding amount of the mixed medicine and mixed material during the feeding limiting period is one third of the normal food intake, and the feeding amount of the mixed medicine and mixed material is recovered to the normal food intake after the feeding limiting period.

In a third aspect, the embodiment of the invention provides a feed suitable for pregnant sows, which comprises a pregnant sow compound feed and the pharmaceutical compositions of the previous embodiments, wherein the mass ratio of the pharmaceutical compositions to the pregnant sow compound feed is X/1000, wherein X is the sum of the weight parts of the components of the pharmaceutical compositions of the previous embodiments.

The invention has the following beneficial effects:

Through the matching use of the medicines of the components, the stomach-calming powder can invigorate stomach and promote digestion, the magnesium sulfate clears away heat and expels toxin, the coptis root detoxification powder clears away heat and cools blood and stops diarrhea, the licorice granules regulate the middle warmer and detoxify, the glucose powder, the enzyme probiotics or the yeast culture regulate the intestinal flora and the organism metabolism, the astragalus polysaccharide powder can improve the immunity and the resistance of the pig body, the lingqi Jinvita can regulate and promote growth, the wrinkled gianthyssop vital qi-strengthening powder clears away heat and detoxify, prevent sunstroke and cool down (prevention effect), the sodium selenite and the body resistance strengthening powder improve the production performance of the sow, the tilmicosin or the tiamulin clear away the lung and relieve cough (treatment effect), the formula can improve the constipation condition of the sow, strengthen the recovery health of the organism, the original physiological function of the organism per se is excavated, the specific immune defense mechanism of the sow is improved, the health, the production benefit is improved.

Drawings

In order to more clearly illustrate the technical effects of the embodiments of the present invention, the drawings that are required to be used in the embodiments will be briefly described below, it being understood that the following drawings illustrate only some embodiments of the present invention and are therefore not to be considered limiting of scope, and that other related drawings may be obtained from these drawings by those of ordinary skill in the art without inventive effort.

FIG. 1, FIG. 2 and FIG. 3 are photographs of pregnant sows fed in accordance with the comparative example;

fig. 4 and 5 are photographs of pregnant sows fed according to the schedule of examples 1-4.

Detailed Description

in order to make the objects, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below. The examples, in which specific conditions are not specified, were conducted under conventional conditions or conditions recommended by the manufacturer. The reagents or instruments used are not indicated by the manufacturer, and are all conventional products available commercially.

The following is a detailed description of a pharmaceutical composition and a pharmaceutical feed suitable for sows in gestation according to the embodiments of the present invention.

The inventor finds that the metabolic disturbance, toxin accumulation, constipation and the like in the sow body are easily caused due to the existing large-scale breeding condition, the reduction of the immunity of the sow during the gestation period, the unreasonable feeding method and the like, so that the number of farrowing of the sow and the proportion of healthy piglets are reduced, and the proportion of stillbirth is increased.

Therefore, the inventor provides a health care scheme formed by the pharmaceutical composition and the use method thereof through a large amount of time of research and practice, and through mutual matching of the pharmaceutical components, the pharmaceutical composition is added into the compound feed for the sows in the gestation period by a small amount of reasonable methods for mixing and feeding, so that the body metabolism and the immune function of the sows can be adjusted, the body recovery is strengthened, the original physiological function of the sows is excavated, the instinct specific immune defense mechanism of the sows is promoted, the purpose of health of a swinery is achieved, the potential of the sows is excavated, the health level is improved, and the production benefit is improved.

it should be noted that tiamulin can be added with different antibacterial agents according to the actual conditions of the swinery and seasonal changes, for example: tilmicosin, amoxicillin, florfenicol and the like, and the dosage can be adjusted according to seasons and the health condition of the swinery. The added enzyme probiotics can be replaced by yeast culture, the dosage of the yeast culture can be properly increased or decreased according to the requirements and health degree of the swinery, and the season and health condition of the swinery are adjusted.

Wherein, the stomach calming powder mainly comprises rhizoma atractylodis, magnolia officinalis, tangerine peel and liquorice. It takes rhizoma atractylodis as a monarch drug, and takes the rhizoma atractylodis as a pungent, fragrant, bitter and warm drug, which can dry dampness and invigorate spleen when entering middle energizer; the officinal magnolia bark is used as a ministerial drug, is aromatic and bitter in flavor and dry in property, is good at promoting the circulation of qi and eliminating the fullness, can eliminate dampness, is compatible with the rhizoma atractylodis, promotes the circulation of qi to eliminate dampness, eliminates dampness to activate the spleen, enables qi stagnation to be carried out, and removes damp turbidity; the dried orange peel is used as an adjuvant to regulate qi and stomach, dry dampness and enliven spleen, so as to help the forces of the rhizoma atractylodis and the magnolia officinalis. The liquorice is used for harmonizing the effects of the medicines and regulating qi, strengthening spleen and stomach. It has effects of regulating spleen and stomach, eliminating dampness, activating spleen, promoting qi circulation, regulating stomach function, and enhancing nutrient absorption ability of sow.

The Chinese medicine powder for detoxicating Chinese goldthread consists of four kinds of Chinese medicinal materials, including Chinese goldthread, skullcap root, phellodendron bark and cape jasmine. Wherein the coptis chinensis has the functions of clearing heat, drying dampness, purging fire and detoxifying; the scutellaria has the effects of clearing heat, drying dampness, purging fire, removing toxin, stopping bleeding and preventing miscarriage, has the inhibition effect on various gram-positive bacteria, gram-negative bacteria and various viruses, and can also inhibit pathogenic bacteria, regulate the immune function of animals and improve the disease resistance; the phellodendron bark has the effects of clearing heat, drying dampness, purging fire, removing toxin and removing bone steaming, also has broad-spectrum antibacterial action, has strong inhibiting effect on various dysentery bacilli, has the effect of resisting influenza viruses and has obvious selective inhibiting effect on hepatitis B surface antigen; gardenia has the functions of purging fire, relieving restlessness, clearing heat, promoting urination, cooling blood and removing toxicity. In the coptis antidotal powder, the antibacterial activities of scutellaria baicalensis and phellodendron amurense have synergistic effect, and the scutellaria baicalensis and phellodendron amurense have stronger inhibiting and killing effects on tubercle bacillus and leptospira, and have obvious inhibiting effect on various fungi and trichomonas. The milk powder is applied before and after the delivery of the sow, and has the effects of improving milk quality, purifying intestinal diseases such as yellow-white dysentery, acute enteritis, bacillary dysentery and the like, improving the level of maternal antibodies in milk and improving the survival rate of piglets.

The astragalus polysaccharide powder has antiviral, antibacterial, anti-stress, antioxidant, immunity regulating, and intestinal tract protecting effects. Astragalus polysaccharide is an interferon inducer, and the antiviral principle is as follows: stimulating the functions of macrophage and T cell, increasing the number of E ring forming cells, inducing cytokine, promoting interleukin induction, and making animal produce endogenous interferon, so as to achieve the goal of resisting virus. The antibacterial action mechanism is multifaceted, on one hand, the antibacterial agent directly inhibits and detoxifies bacteria and toxic products thereof, and on the other hand, the antibacterial agent plays a role in bacteriostasis and sterilization mainly by mobilizing the immune defense function of the organism. It has antibacterial effect on Shigella shigella, Bacillus anthracis, Streptococcus hemolyticus a and B, Diplococcus pneumoniae, Staphylococcus aureus, Escherichia coli, and Salmonella. The intestinal tract protection function is realized by reducing the pH value of the intestinal tract, stimulating the intestinal tract to creep, reducing the number of pathogenic bacteria and increasing the number of beneficial bacteria, and meanwhile, the beneficial bacteria can generate metabolites with antibacterial activity, such as hydrogen peroxide, organic acid and the like in the proliferation process, and can inhibit the survival of pathogenic harmful bacteria and exogenous pathogenic bacteria. Therefore, the immunity and the resistance of the sow body can be improved by eating the astragalus polysaccharide powder.

The glucose powder contains multiple vitamins and glucose, and has effects of supplementing in vivo heat and protecting liver. Mainly used for relieving some hypoglycemia symptoms and can also relieve some body energy deficiency symptoms. Glucose is easily absorbed through the blood and quickly distributed throughout the body, it is absorbed in the intestine, protects the regulatory body from recovery, and is reabsorbed in the kidney, and by means of special transporters (cell membrane proteins) crossing the barriers between the blood and the tissues, it achieves the effect of timely relieving and regulating the body fluid. Glucose is beneficial to brain tissue cell activation, stimulates calcium absorption and increases intercellular communication. The glucose powder is matched with the Pingweisan powder for use, so that the digestion and absorption capacity of the sows can be enhanced in an auxiliary manner, the metabolism of the sows is regulated, and the sows can restore the normal physiological functions of the bodies.

The Jinweita is mainly the lingqi Jinweita or 21 Jinweita, contains a plurality of vitamins, amino acids, a plurality of trace elements and special cell nutrition factors, can effectively improve the immunity, prevent various stress reactions (such as vaccination, group transfer, severe summer heat, severe cold and the like), enhance the disease resistance of organisms, promote the healthy growth of livestock and poultry, enhance the hair color and luster of the livestock and poultry, improve the carcass quality, improve the feed reward and increase the breeding benefit. Vitamins are low molecular organic compounds necessary for maintaining normal life activities of animals and ensuring production performances of animals such as growth, reproduction and the like, and can promote metabolism of organisms, enhance the resistance of the organisms to diseases and regulate electrolyte balance of the organisms. The trace elements have obvious regulating effect on various stresses of all growth stages of livestock and poultry. The special cell nutrition factor can stimulate the gastrointestinal tract tissue to absorb and utilize nutrient substances, better promote feed digestion, improve feed conversion rate, obviously increase the weight of livestock and poultry, activate the immune function for acquired immunodeficiency, improve the immunity of organisms, combine with virus receptors, block viruses from entering host cells, and effectively prevent various virus diseases.

The Glycyrrhrizae radix granule has effects of regulating stomach, removing toxic substances, resisting virus, resisting inflammation, resisting bacteria, eliminating phlegm, relieving cough, relieving spasm, relieving pain, and harmonizing the drugs. The composition can be used for preventing and treating swine enzootic pneumonia, infectious pleuropneumonia, infectious atrophic rhinitis, streptococcosis, haemophilus parasuis disease, pneumonitis, acute and chronic respiratory tract diseases such as bronchitis, swine influenza, pasteurellosis, mycoplasma pneumonia, swine fever, swine reproductive and respiratory syndrome, swine streptococcosis, swine influenza, reproductive and respiratory syndrome, pseudorabies, circovirus, and blister disease of hoof. Can be used in combination with any medicine to rapidly improve curative effect, accelerate organism rehabilitation, and improve cure rate.

The magnesium sulfate has the functions of clearing and expelling toxin, and can reduce toxin in the sow body, so that the metabolic function and the like of the sow can be recovered to be normal. And the sodium selenite regulates the absorption and utilization of vitamin A, vitamin C, vitamin E and vitamin K in the sows, enhances the protein synthesis function of the sows and can enhance the reproductive function of the sows.

The body resistance strengthening powder is a new generation antiviral compound preparation combined with Chinese and western medicines, has broad-spectrum disease-resistant activity on various DNA viruses and RNA viruses, has specificity on cell species, can improve the immunity of the organism, and can assist sodium selenite to improve the reproductive function of sows together.

The HUOXIANGZHENGQI powder has effects of clearing away heat and toxic materials, preventing heatstroke, regulating the middle warmer, relieving vomit, dispelling pathogenic wind and cold, eliminating turbid pathogen, activating qi-flowing, eliminating dampness, eliminating stagnation, invigorating spleen, eliminating dampness, and regulating spleen and stomach.

the enzyme-added probiotics is a living microbial preparation, contains a large amount of beneficial bacteria and metabolites thereof and growth promoting factors, has the characteristics of no toxicity, no side effect, maintenance of intestinal microbial balance, promotion of animal growth, improvement of feed conversion rate, enhancement of immune function of animal organisms and the like, and is widely used in livestock and poultry breeding industry at present.

Doxycycline is a semisynthetic tetracycline antibiotic obtained by 6 alpha-position deoxidation of oxytetracycline, and the preparation is hydrochloride. The mechanism is the same as that of tetracycline, and mainly interferes with protein synthesis of sensitive bacteria. It can specifically bind to the bacterial ribosomal 30S subunit at the A position, thereby inhibiting the attachment of the aminoacyl-tRNA at that position, preventing the elongation of the peptide chain; doxycycline also changes the permeability of bacterial cell membranes, leaking nucleotides and other important components out of the cells, and thus inhibiting the replication of bacterial DNA. Doxycycline has strong antibacterial activity against Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, gonococcus, meningococcus, Escherichia coli, Aerobacter, Shigella, Yersinia, Listeria monocytogenes, etc., and also has certain effect on Rickettsia, Mycoplasma, Chlamydia, Actinomycetes, etc. The antibacterial spectrum is basically the same as that of tetracycline and terramycin, and the in vivo and in vitro antibacterial power is stronger than that of tetracycline.

The antibacterial spectrum of the tiamulin is similar to that of macrolide antibiotics, and the tiamulin mainly resists gram-positive bacteria and has stronger inhibiting effect on staphylococcus aureus, streptococcus, mycoplasma, porcine actinobacillus pleuropneumoniae, porcine treponema dysentery and the like.

Stomach strengthening and digestion promoting are achieved through stomach calming powder, intestinal waste is cleared through magnesium sulfate clearing and toxin expelling, heat clearing and blood cooling are achieved through coptis toxin expelling powder to clear toxins in blood, organism metabolism is regulated through glucose powder and prebiotics added with enzyme to excavate and restore normal physiological functions of an organism, immunity and resistance of pigs are improved through astragalus polysaccharide powder and doxycycline, growth is promoted through the Jinvita, disease preventing effect is achieved through licorice particle neutralization and wrinkled gianthyssop vital energy dispersing heat clearing and toxin expelling, sunstroke preventing and cooling, sow production performance is improved through sodium selenite and body resistance strengthening powder to achieve health care in advance, and respiratory diseases are treated through tilmicosin. All the medicines in the prescription have the mutual cooperation effect, so that the health recovery of the body can be accelerated, the original physiological function of the sow can be dug out, the immune defense performance of the sow can be improved, the aim of health of the swinery can be fulfilled, and the production benefit can be improved.

Meanwhile, the use of the above-mentioned drugs requires strict dosage restrictions, otherwise excessive use of the drugs may cause the drugs to remain in the pork and adversely affect the production of sows. Therefore, the use method of the pharmaceutical composition comprises the following steps: the medicine components in the scheme are uniformly mixed according to parts by weight, then the mixture is uniformly stirred with a compound feed for sows in the gestation period according to the weight ratio of X/1000, and then the mixture is fed, wherein X is the sum of the parts by weight of the components of the medicine composition, the medicine is used once in 20-30 days, the medicine is continuously mixed once for 7-10 days, and the medicine can be fed for 2-3 times in two months.

It should be noted that the drug care generally follows a seasonal and chronological order, such as: tilmicosin can be used to replace tiamulin in spring to achieve the purpose of treating diseases, and tiamulin is preferably used in summer, autumn and winter. The dosage of each component in the prescription can be adjusted according to the region, weather condition and swinery condition, but cannot be absolutely replaced.

In the implementation mode, feeding is limited for 0.5-1 day before the medicines are fed, feeding is not carried out during the feeding limiting period, sufficient and clean drinking water is provided, sanitation and dryness of the colony house are kept, and the colony is firm. The hungry the swinery during the feeding limiting period, the better the administration effect. During hunger, the secretion of digestive tract glands of the body is increased, so that the digestive absorption is easier, and during hunger, the secretion of saliva is increased most, digestive juice, digestive enzyme, pancreatic juice and the like, so that the body is promoted to be emptied, the body is convenient to accelerate the regulation speed, and the medicine can be absorbed and utilized more quickly and effectively after reaching the body, thereby achieving the purpose of short-term medicine taking and high efficiency. When the medicine is fed, the feeding is limited for 2-3 days, the medicine mixing and feeding amount is adjusted to be one third of the normal food intake during the feeding limit period, and the medicine mixing and feeding are carried out according to the normal food intake after the feeding limit period. If the feeding amount is not limited during the administration period, firstly, the medicine feeding effect is poor, and some pigs do not eat due to the peculiar smell of the medicine; secondly, the regulation speed of the feeding over-protection organism is slow, the medicine taking time needs to be prolonged, the medicine dosage needs to be increased, and more importantly, the health care effect is not obvious in a short period, and the regulation period is prolonged.

In a third aspect, some embodiments of the invention provide a feed suitable for pregnant sows, which comprises a pregnant sow compound feed and the pharmaceutical compositions of the previous embodiments, wherein the mass ratio of the pharmaceutical compositions to the pregnant sow compound feed is X/1000, wherein X is the sum of the proportioning parts by weight of the components of the pharmaceutical compositions of the previous embodiments.

The features and properties of the present invention are described in further detail below with reference to examples.

The lingqi jinweita in the following examples was purchased from great biotechnology limited of beijing pasture; yeast cultures were purchased from Ningxia Yipin Biotech Ltd; the magnesium sulfate and the sodium selenite are feed grade, and other components are conventional commercial products which can be purchased in the market. The feeding in the examples was normally three times per day.

Example 1

The pharmaceutical composition comprises, by weight, 16 per mill of glucose powder, 13 per mill of stomach calming powder, 0.4 per mill of coptis detoxification powder, 1 per mill of astragalus polysaccharides powder, 1.4 per mill of wrinkled gianthyssop vital energy powder, 1.5 per mill of body resistance strengthening powder, 1.2 per mill of lingzhijintada, 1.2 per mill of liquorice particles, 0.5 per mill of sodium selenite, 2.5 per mill of magnesium sulfate, 0.8 per mill of doxycycline, 0.4 per mill of tiamulin and 1 per mill of zymolytic probiotics.

The using method comprises the following steps: the medicine components are uniformly mixed according to parts by weight, and then are uniformly mixed with a compound feed for the sows in the gestation period according to the weight ratio X/1000 for feeding, the medicine is continuously mixed and stirred for 7-10 days once every 20-30 days, and the medicine can be reduced to two months once after 2-3 times of continuous use; feeding is limited for 0.5-1 day before dosing, feeding is not carried out during the feeding limiting period, sufficient and clean drinking water is provided, sanitation and dryness of the colony house are kept, and the pen is firm; the initial period of the feeding is 2 to 3 days, the feeding amount of the mixed drug and the mixed feed is one third of the normal food intake during the feeding limit period, and the mixed drug and the mixed feed is fed according to the normal food intake after the feeding limit period.

Example 2

The pharmaceutical composition comprises 18 per mill of glucose powder, 14 per mill of stomach calming powder, 0.5 per mill of coptis detoxification powder, 1 per mill of astragalus polysaccharides powder, 1.2 per mill of wrinkled gianthyssop vital qi powder, 1 per mill of body resistance strengthening powder, 1 per mill of astragalus vitamine, 1 per mill of licorice particles, 0.4 per mill of sodium selenite, 2.5 per mill of magnesium sulfate, 0.6 per mill of doxycycline, 0.6 per mill of tilmicosin and 50 per mill of yeast culture according to the weight ratio.

The procedure is as in example 1.

Example 3

The pharmaceutical composition comprises, by weight, 16 per mill of glucose powder, 14 per mill of stomach calming powder, 0.4 per mill of coptis detoxification powder, 1.2 per mill of astragalus polysaccharides powder, 1.5 per mill of body resistance strengthening powder, 1.2 per mill of lingqijintada, 1.2 per mill of liquorice particles, 0.4 per mill of sodium selenite, 2.8 per mill of magnesium sulfate, 1 per mill of doxycycline, 0.6 per mill of tiamulin and 70 per mill of yeast culture.

The procedure is as in example 1.

Example 4

The pharmaceutical composition comprises, by weight, 16 per mill of glucose powder, 13 per mill of Pingwei san, 0.3 per mill of rhizoma Coptidis detoxification powder, 1.5 per mill of astragalus polysaccharides powder, 1 per mill of wrinkled Gianthyssop vital qi powder, 1.5 per mill of body resistance strengthening powder, 1 per mill of lingzhijintada, 1.2 per mill of licorice granules, 0.5 per mill of sodium selenite, 2.5 per mill of magnesium sulfate, 0.8 per mill of doxycycline, 0.5 per mill of tiamulin and 70 per mill of yeast culture.

The procedure is as in example 1.

Test examples

Performing experiments in Gansu Tianshui Hongfeng aquaculture professional cooperative, randomly dividing 150 healthy gestation sows with similar miscarriages and mating dates into 5 groups of 30 sows each, wherein one group is a comparative example, managing according to the original feeding management mode of a pig farm, feeding no medicine, and feeding the other 4 groups of sows according to the original feeding management mode of the pig farm according to the examples 1-4. The test period is 4 months. At the beginning of the test, the body condition, the hair color and the stool form of each group of sows are recorded, during the test, the feed intake of each group of sows is recorded, the breeding date is on the same date, and when the test is finished, the litter size, the healthy litter size, the weak litter size, the dead litter size, the average birth weight and the dystocia of each group of sows are recorded.

The test results are shown in the following table:

In addition, the example and comparative group of herds were focused on constipation, hair color, mental state, dystocia during the trial. The comparison shows that the sows in the comparative example group have more constipation, low feed intake, rough and disordered back hair, more dystocia and anorexia and lassitude after delivery of part of sows; the sows in the group of the examples have good body conditions, high feed intake, bright back hair, less constipation, good spirit, less dystocia and no anorexia after delivery. Referring to fig. 1 to 3, fig. 4 to 5 show the comparison between the sow of the comparative example and the sow of examples 1 to 4, respectively. As can be seen from fig. 1, 2 and 3, the sows which do not adopt the pharmaceutical composition of the embodiment of the invention for health care have emaciation, sarcoptidosis, coarse and long hair, constipation, poor mental status and less farrowing, while as can be seen from fig. 4 and 5, the sows which adopt the pharmaceutical composition of the embodiments 1 to 4 of the invention for health care have bright hair, good mental status, more farrowing, good milk, big birth weight of piglets and fast growth. Furthermore, the data in the table show that the litter size of the example group is increased by 8.3% -9.3%, the weak litter size is reduced by 2.4% -2.8%, the dead fetus size is reduced by 3.1% -3.4%, the average birth weight is increased by 8.3% -9.8%, and the technical effect is obvious.

The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, improvement and the like made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. The pharmaceutical composition suitable for the sows in the gestation period is characterized by comprising the following components in parts by weight: 13-14 parts of stomach calming powder, 16-18 parts of glucose powder, 0.3-0.5 part of coptis detoxifying powder, 1-1.5 parts of astragalus polysaccharide powder, 1-1.2 parts of Jinweita, 1-1.2 parts of licorice particles, 2.5-2.8 parts of magnesium sulfate, 0.4-0.5 part of sodium selenite, 1-1.5 parts of body resistance strengthening powder, 1-1.4 parts of wrinkled gianthyssop vital energy strengthening powder, 0.6-1 part of doxycycline, 0.4-0.6 part of tiamulin and 1 part of enzymic prebiotics.

2. The pharmaceutical composition of claim 1, wherein the Jinweita is lingqi Jinweita or 21 Jinweita.

3. The pharmaceutical composition of claim 1, wherein the pharmaceutical composition is administered by: the components of the pharmaceutical composition are uniformly mixed according to the parts by weight, and then the pharmaceutical composition and the compound feed for pregnant sows are uniformly stirred and fed according to the weight ratio of X/1000, wherein X is the sum of the parts by weight of the components of the pharmaceutical composition.

4. The pharmaceutical composition of claim 3, wherein the pharmaceutical composition is used at a frequency and for a duration of: when the medicine composition is used for the first time, the medicine composition is used once in 20-30 days, the medicine composition is continuously mixed with the pregnant sow compound feed once, the medicine is fed for 7-10 days, and the medicine is used for 2-3 times continuously and is reduced to be once in two months.

5. The pharmaceutical composition according to claim 1, wherein the pharmaceutical composition is administered for 0.5-1 day, and the administration requirement is: during the feeding limiting period, no feeding is needed, sufficient and clean drinking water is provided, the colony house is kept sanitary and dry, and the colony is firm.

6. The pharmaceutical composition of claim 5, wherein the pharmaceutical composition requires 2-3 days of restricted feeding during the first three days of administration, the amount of the dressing feed during the restricted feeding period is one third of the normal feed intake, the dressing feed is fed for 2 days, 3-4 times per feeding period, and the feed amount is returned to the normal feed intake.

7. The feed suitable for the pregnant sows is characterized by comprising a pregnant sow compound feed and the pharmaceutical composition as defined in any one of claims 1 to 6, wherein the mass ratio of the pharmaceutical composition to the pregnant sow compound feed is X/1000, and X is the sum of the weight parts of the components of the pharmaceutical composition as defined in any one of claims 1 to 6.