CN103238754B - Compound premix for quick delivery and postpartum recovery of sow and preparation process thereof - Google Patents
Compound premix for quick delivery and postpartum recovery of sow and preparation process thereof Download PDFInfo
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Abstract
The invention relates to a feed, and in particular relates to compound premix for quick delivery and postpartum recovery of a sow and a preparation process thereof. The compound premix consists of a thymus extract, a rabbit muscle extract, brown sugar and the like, and is green compound premix which is free from substances leading to carcinogenesis, teratogenesis and mutagenesis. The premix has the effects of accelerating the sow for quick delivery and promoting postpartum recovery, enhancing the immunity of animals, improving the disease resistance of animals and reducing the incidence of the disease of a piglet.
Description
Technical field
The present invention relates to feed, particularly a kind of compound premix and preparation technology thereof for the quick childbirth of sow and postpartum recovery.
Background technology
Female swine rearing is the important step in Swine Production, and the nursing of sows in perinatal period is the key of survival of piglets, is also breeding enterprise synergy growth point.Breeding enterprise is conventionally extremely careful during sows in perinatal period is antenatal 7 days to 7 days postpartum, and antenatal preparation is in delivery room environmental sanitation, Temperature and Humidity Control, the equipment disinfection of practicing midwifery, sow feeding management strict implement standard; In birth process nursing practicing midwifery, practise midwifery, fortuitous event is processed and is had a whole set of measure in childbirth, birth process in batch; The nursing in sow postpartum feeding, environmental sanitation, postpartum do not eat processing, refuse lactation processes and have effective way yet.This plays positive role to the death rate after reducing piglet birth a couple of days or after wean.But perinatal period, sow was a large difficulty of all pig farms nursing.The most thorny issue is PNI problem, most of pig farm is chosen in antenatal 7 days and adds antibiotic medicine, farrowing administration on the same day, continue again administration 7 days postpartum, but still can't resolve PNI problem, and likely cause that intrauterine environment worsens, cause breeding to return the problem that feelings sow increases, sow stages of labor is long or have difficult labour.Antibiotic abuse, 1. causes the generation of antibody-resistant bacterium; The inhibition of pair animal intestinal probio with kill, cause flora imbalance, cause body suprainfection; 3. cause the damage in various degree of animal kidney, liver, nervous system, hematological system; 4. cause the imbalance of animal endocrine function, enzyme system secretion capacity reduces or is disorderly, directly affects animal digestive system function; 5. suppress growing or having reduced the immunologic function of animal of animal immune system, the premunition of animal declines.
In view of the deficiency of above technology, research and develop and a kind ofly maintain that sow is antenatal, postpartum energy, after Farrowing, can recover rapidly healthy, and improve pigling immunity product extremely urgent.
Summary of the invention
The object of the present invention is to provide a kind ofly for sow fast compound premix and the preparation technology thereof of childbirth and postpartum recovery, this compound premix has the effect that the premunition of energy, storage power, shortening stages of labor, enhancing sow and piglet is provided to sow and piglet.
The object of the invention is to realize by following approach: a kind of compound premix for the quick childbirth of sow and postpartum recovery, by weight percentage, it consists of following component: thymic extract 1-25%, rabbit flesh extract 1-15%, brown sugar 5-25%, potassium sorbate 0.2-0.5%, water 34.5-92.8%.
As the further optimization of this programme, by weight percentage, it consists of following component: thymic extract 12%, rabbit flesh extract 7.5%, brown sugar 20%, potassium sorbate 0.5%, water 60%.
As the further optimization of this programme, by weight percentage, it consists of following component: thymic extract 20%, rabbit flesh extract 15%, brown sugar 20%, potassium sorbate 0.5%, water 44.5%.
As the further optimization of this programme, described thymic extract refers to the peptide material extracting from ox, pig, chicken animal thymus.
A kind of step of preparation process of the compound premix for the quick childbirth of sow and postpartum recovery is as follows:
A. the preparation of thymic extract:
A. get healthy animal thymus gland and thaw, degrease, rubs;
B. hydrolysis: the water of 1 kilogram of thymus gland amount of doubling, heat to 40-60 ℃, add complex enzyme 2000-3000 U, add 40% sodium hydroxide solution and adjust pH value to 7.5-9.0, enzymolysis 10hr;
C. deactivation: get hydrolyzate, be heated to 100 ℃, be incubated 10 minutes, obtain thymic extract, put in closed container, cooling standby;
B. the preparation of rabbit flesh extract:
A. healthy rabbit is slaughtered, rapidly peeling, gets in the cold water that dorsal muscles and leg flesh sets to 0-4 ℃ or puts refrigerator freezing, rubbing;
B. alcohol is processed: the rabbit flesh of rubbing is put to 2-3 and doubly measure in ice ethanol, stir 30 minutes, filter, get filter residue and add 2-3 again and doubly measure ice ethanol, stir 30 minutes, merge ice ethanol filtrate for the first time, be heated to seethe with excitement 5 minutes, filter;
C. dissolve: get filter residue and put in the cold water of 0-4 ℃ of 2 times of amount, stir 30 minutes; Filtrate after filtration adds glacial acetic acid and adjusts pH value to 2.0-4.0, obtains rabbit flesh extract standby;
C. allotment: get thymic extract, rabbit flesh extract, brown sugar, potassium sorbate and water and prepare in proportion, after filtering, packing gets product.
A kind of compound premix for the quick childbirth of sow and postpartum recovery of the present invention, based on following theoretical foundation, develop research: sows in perinatal period is except carrying out antenatal preparation, in birth process outside the nursery work in nursing, sow postpartum, improve growing or improving the immunologic function of piglet of piglet immunological system, the premunition that strengthens piglet should be fed and set about in the antenatal science of sow, is mainly in the improvement of health based on the sow production performance that is embodied in piglet; During Farrowing, physical consumption is very large, the energy consuming while how to guarantee to supplement Farrowing in time, and it is crucial shortening stages of labor; Physical efficiency recovery after Farrowing, guarantees that sow has sufficient milk, and piglet can obtain more IgG from the milk of sow, after weaned piglet, feeds in time and promotes to improve the resistance against diseases of piglet by the product that piglet immunological system is grown.The compound premix of developing will make piglet not fall ill or few morbidity, improves the survival rate of piglet, makes breeding enterprise synergy.
A kind of compound premix for the quick childbirth of sow and postpartum recovery of the present invention, compared with the prior art: have following innovation:
One, composition:
1. prior art: sows in perinatal period is according to resistance in antibiotic.
2. the art of this patent: sows in perinatal period provides a kind of containing thymic extract, rabbit flesh extract, the compound premix of brown sugar.
Two, mechanism:
1. prior art: application antibiotic anti-bacteria cell membrane synthetic; Increase the permeability of bacterial cell membrane; Stop peptide elongation or blocking peptide acyl group to shift CKIs matter synthetic, the growth of bacterium is suppressed; But antibiotic abuse, 1. causes the generation of antibody-resistant bacterium; The inhibition of pair animal intestinal probio with kill, cause flora imbalance, cause body suprainfection; 3. cause the damage in various degree of animal kidney, liver, nervous system, hematological system; 4. cause the imbalance of animal endocrine function, enzyme system secretion capacity reduces or is disorderly, directly affects animal digestive system function; 5. suppress growing or having reduced the immunologic function of animal of animal immune system, the premunition of animal declines.
2 the art of this patent: setting about at the antenatal science of the sow patented product of feeding, is mainly in the improvement of health based on the sow production performance that is embodied in piglet; During Farrowing, physical consumption is very large, the energy consuming while how to guarantee to supplement Farrowing in time, and giving sow makeup energy is crucial with shortening stages of labor; Physical efficiency recovery after Farrowing, guarantees that sow has sufficient milk, and piglet can obtain more IGg from the milk of sow, after weaned piglet, feeds in time and promotes to improve the resistance against diseases of piglet by the product that piglet immunological system is grown.Piglet is not fallen ill or few morbidity, improve the survival rate of piglet, make breeding enterprise synergy.Research and develop and a kind ofly maintain that sow is antenatal, postpartum energy, after Farrowing, can recover rapidly healthy.
Thymic extract master is containing protein, polypeptide, amino acid and nucleic acid.The composition of polypeptide is thymic peptide, and the active component of thymic peptide is Thymosin alpha 1, is the polypeptide that 28 amino acid form.There is the effect of adjusting and enhancing animal cell immunity function, can impel the T lymphocyte in the peripheral blood after mitogen activates ripe, increase the secretion of T cell various lymphokines after various antigen or the former activation of mitogenesis, increase the level of lymphokine acceptor on T cell.It is simultaneously by strengthening lymphocyte reaction to the activation of T4 auxiliary cell.In addition, this product may affect the chemotactic of NK precursor, and this precursor becomes after being exposed to interferon more cytotoxicity.Therefore, this product has the effect of adjusting and enhancing animal somatic cell immunologic function.
Rabbit flesh extracts owner containing atriphos (ATP), and ATP is a kind of coenzyme.Participate in the metabolism of animal body fat, protein, sugar, nucleic acid and nucleotides.When absorption in body, secretion, contraction of muscle and the biochemical synthetic reaction etc. of carrying out need energy, atriphos resolves into adenosine diphosphate (ADP) and phosphate, give off energy simultaneously, atriphos can penetrate blood cerebrospinal fluid barrier, can improve the stability of nerve cell membranous structure and reconstruction ability, promote the regrowth of nervous process.ATP and pentose in vivo can nucleic acids under the effect of enzyme; Under the effect of dysuria due to the pressure of the fetus thuja acid enzyme, can synthesize cephalin and monophosphate cytidine with phosphatide cholamine.
Brown sugar has almost retained the whole compositions in sugarcane juice, except possessing sugared function, also contains vitamin and trace element, as nutritional labelings such as iron, zinc, manganese, chromium.The traditional Chinese medical science thinks, brown sugar is warm in nature, taste is sweet, enter spleen, have blood-enrich, the warm stomach of invigorating the spleen, slow in pain relieving, the effect that activates blood circulation and disperses blood clots.According to data, record, 900 milligrams of 1000 grams of brown sugar calcics, 100 milligrams of iron, and calcium, iron are also the essential mineral matter of animal body and trace element.An expert measures with AFS, finds that brown sugar contains very abundant Trace Elements, and wherein some trace elements has the function of intense stimulus body hematopoiesis.It seems that therefore, perinatal period, the sow to postpartum took nourishing food to build up one's health with brown sugar, be very reasonable.
Three, technique
1. prior art: extract Thymosin alpha 1 and adopt freeze-thaw method to extract from thymus gland, one pack system application conventionally.
2. the art of this patent: extract Thymosin alpha 1 and adopt enzymatic isolation method to extract from thymus gland, and retained other compositions in thymus gland, and form compound preparation with rabbit flesh extract, brown sugar.
Four, application
1. prior art: have no sows in perinatal period application.
2. the art of this patent: adopt dialectical the treating of Chinese veterinarian to debate disease with doctor trained in Western medicine and treat know-why and combine, the health of sow is embodied in the production performance improvement of piglet, sows in perinatal period is except carrying out corresponding nursery work, focused on the health care of sow, antenatal application this patent product, improve animal mothers and sons resistance against diseases, can supplement in time sow causes Power supply not enough because reducing scale of feeding before just before giving birth, suitably supplement ATP, the one, storage power, the 2nd, when childbirth, release energy, reduce childbirth resistance, shorten stages of labor, realize the object of protection fetus, improve childbirth fetus survival rate, reduce fetus diarrhea rate.Divide the puerperium, sow application this patent product, promotes sow to recover physical efficiency, increases milk, minimizing mammitis, the metritic incidence of disease.
The specific embodiment
A kind of compound premix for the quick childbirth of sow and postpartum recovery of the present invention, by weight percentage, it consists of following component: thymic extract 1-25%, rabbit flesh extract 1-15%, brown sugar 5-25%, potassium sorbate 0.2-0.5%, water 34.5-92.8%.
As the best proportioning of this programme, by weight percentage, it consists of following component this compound premix: thymic extract 12%, rabbit flesh extract 7.5%, brown sugar 20%, potassium sorbate 0.5%, water 60%.
As another best proportioning of this programme, by weight percentage, it consists of following component this compound premix: thymic extract 20%, rabbit flesh extract 15%, brown sugar 20%, potassium sorbate 0.5%, water 44.5%.
Described thymic extract refers to the peptide material extracting from ox, pig, chicken animal thymus.
A kind of compound premix for the quick childbirth of sow and postpartum recovery of the present invention, is characterized in that: the step of preparation process of this compound premix is as follows:
A. the preparation of thymic extract:
A. get healthy animal thymus gland and thaw, degrease, rubs;
B. hydrolysis: the water of 1 kilogram of thymus gland amount of doubling, heat to 40-60 ℃, add complex enzyme 2000-3000 U, add 40% sodium hydroxide solution and adjust pH value to 7.5-9.0, enzymolysis 10hr;
C. deactivation: get hydrolyzate, be heated to 100 ℃, be incubated 10 minutes, obtain thymic extract, put in closed container, cooling standby;
B. the preparation of rabbit flesh extract:
A. healthy rabbit is slaughtered, rapidly peeling, gets in the cold water that dorsal muscles and leg flesh sets to 0-4 ℃ or puts refrigerator freezing, rubbing;
B. alcohol is processed: the rabbit flesh of rubbing is put to 2-3 and doubly measure in ice ethanol, stir 30 minutes, filter, get filter residue and add 2-3 again and doubly measure ice ethanol, stir 30 minutes, merge ice ethanol filtrate for the first time, be heated to seethe with excitement 5 minutes, filter;
C. dissolve: get filter residue and put in the cold water of 0-4 ℃ of 2 times of amount, stir 30 minutes; Filtrate after filtration adds glacial acetic acid and adjusts pH value to 2.0-4.0, obtains rabbit flesh extract standby;
C. allotment: get thymic extract, rabbit flesh extract, brown sugar, potassium sorbate and water and prepare in proportion, after filtering, packing gets product.
embodiment 1:
1.1 test material
1.1.1 experimental animal and feed
1.1.1.1 sow perinatal period is used in test: be grow up (binary is assorted).
1.1.1.2 basal diet:
Sow: daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.
Corn, fish meal, dregs of beans, wheat bran, trace element.Hunan Xiang Jiuyang feed corporation,Ltd.
for reagent product and reagent
1.1.2.1 the quick compound premix (liquid state) of childbirth and postpartum recovery of sow: be that Hu'nan Sunaccord Biological Technical Co., Ltd.'s research and development are produced.
Prescription: by weight percentage, it consists of following component: thymic extract 12%, rabbit flesh extract 7.5%, brown sugar 20%, potassium sorbate 0.5%, water 60%.
1.1.2.2 Antibiotics combination (branch former clean+fortimicin+Amoxicillin).
Branch is former clean: Shanghai Novartis;
Fortimicin: Hebei roc of a specified duration;
Amoxicillin: Zhuhai is federal
1.1.2.3 sharp high (Lincomycin Hydrochloride, Spectinomycin Sulfate soluble powder): Suzhou animal health Co., Ltd of Pfizer.
test method
1.2.1 test grouping and processing
1.2.1.1animal used as test grouping:
To test with sow binary assorted (long white, great Bai), 10 every group, be divided at random 4 groups, the close collocation of parity is (3-5 tire) evenly, and the close collocation of body weight is even.
Test method
The design of employing single factor experiment, is divided into 4 groups at random by test pig, and concrete packet transaction scheme is as follows:
A. not dosing group: basal diet
B. Antibiotics combination group: basal diet+Antibiotics combination consumption per day
C. sharp high group: basal diet+sharp high consumption per day
D. the quick compound premix group of childbirth and postpartum recovery of sow: basal diet+every sow 50ml sow feed perinatal period additive
It is experimental subjects that perinatal period sow is take in this test, and daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.By above-mentioned grouping, feed respectively.14 days experimental periods,, antenatal 7 days to 7 days postpartum.
When the beginning of experimental period, to test pig parity, the close overbit of beating of body weight, and carry out homogeneity test, indivedual adjustment makes group difference not remarkable (P>0.05).
grouping and dosage setting foundation
A sow compound premix dosage and two antibiotic medicine experimental group of childbirth and postpartum recovery fast in above-mentioned test, have been set, and set not medication contrast, the basis of design of the compound premix group dosage of the quick childbirth of sow and postpartum recovery is to have set RD with reference to preliminary prerun in early stage.
observe
Duration of test, observes spirit, appetite, activity, the ight soil situation of pig every day, and makes a record, stages of labor while simultaneously recording the antenatal morbidity of sow head, Farrowing, sow appetite in postpartum recovery time, farrowing pig's head number, piglet cradling room morbidity head.
result of the test:in Table 1.
Table 1:
the impact of different disposal on sow production performance
Presentation of results: compound premix group, Antibiotics combination group, the comparison of sharp not dosing of Gao Zuyu control group of the quick childbirth of 50ml sow and postpartum recovery, the antenatal incidence of disease of sow: experimental group is all lower than control group; Stages of labor: experiment d group is less than experiment b, c group, is significantly less than control group, shortens stages of labor 1.9-3 hour; Postpartum, sow appetite was recovered: experiment d group is less than experiment b, c group, is significantly less than control group.The piglet incidence of disease: experiment d group is less than experiment b, c group, is significantly less than control group.
embodiment 2.
2.1 test material
2.1.1 experimental animal and feed
2.1.1.1sow perinatal period is used in test: be grow up (binary is assorted).
Basal diet:
Sow: daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.
Corn, fish meal, dregs of beans, wheat bran, trace element.Hunan Zheng Hong development in science and technology Co., Ltd.
for reagent product and reagent
2.1.2.1feed additive for sows in perinatal period (liquid state): for Hu'nan Sunaccord Biological Technical Co., Ltd.'s research and development are produced.
Prescription: by weight percentage, it consists of following component: thymic extract 12%, rabbit flesh extract 7.5%, brown sugar 20%, potassium sorbate 0.5%, water 60%.
Profit high (Lincomycin Hydrochloride, Spectinomycin Sulfate soluble powder): Suzhou animal health Co., Ltd of Pfizer.
test method
2.2.1 test grouping and processing
2.2.1.1animal used as test grouping:
To test with sow binary assorted (long white, great Bai), 30 every group, be divided at random 4 groups, the close collocation of parity is (3-5 tire) evenly, and the close collocation of body weight is even.
Test method
The design of employing single factor experiment, is divided into 4 groups at random by test pig, and the scheme of specifically dividing into groups is as follows:
A. antibiotic control group: basal diet+sharp high consumption per day
B.25ml the quick compound premix group of childbirth and postpartum recovery of sow: basal diet+every sow 25ml every day feed addictive perinatal period
C.50ml the quick compound premix group of childbirth and postpartum recovery of sow: basal diet+every sow 50ml every day feed addictive perinatal period
D.100ml the quick compound premix group of childbirth and postpartum recovery of sow: basal diet+every sow 100ml every day feed addictive perinatal period
It is experimental subjects that perinatal period sow is take in this test, and daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.By above-mentioned grouping, feed respectively.14 days experimental periods.When the beginning of experimental period, to test pig parity, the close overbit of beating of body weight, and carry out homogeneity test, indivedual adjustment makes group difference not remarkable (P>0.05).
grouping and dosage setting foundation
In above-mentioned test, all set three sows fast the compound premix dosage level of childbirth and postpartum recovery do parallel test, and set an antibiotic medicine control group.Perinatal period, the basis of design of sow feed additive test group dosage was, with reference to preliminary prerun in early stage, had set sow RD 50ml, then take RD as middle dosage, increased or reduce 1 times, had set high dose 100ml and low dosage 25ml.
observe
Duration of test, observes spirit, appetite, activity, the ight soil situation of pig every day, and makes a record, stages of labor, sow morbidity in postpartum head, farrowing pig's head number, piglet cradling room morbidity head while recording the antenatal morbidity head of sow, Farrowing simultaneously.
2.3
result of the test:in Table 2.
Table 2:
the impact of different disposal on sow production performance
Compound premix group and the comparison of antibiotic control group of presentation of results: 25ml, 50ml, the quick childbirth of 100 ml sows and postpartum recovery, the antenatal incidence of disease of compound premix group sow of 50ml, the quick childbirth of 100 ml sows and postpartum recovery is lower than antibiotic control group; Stages of labor: experiment c, d group are less than experiment b group, are significantly less than control group a, and difference is (P < 0.01) extremely significantly, shortens stages of labor 2-2.6 hour, experimental group d and experimental group c comparison, significant difference (P < 0.05); Sow appetite recovery time in postpartum: experiment c, d group are less than experiment b group, are less than control group a, significant difference (P < 0.05).The piglet incidence of disease: experiment c, d group are less than experiment b group and control group a, significant difference (P < 0.05).
In sum: data show, add patented product of the present invention: sow feeding amount 25ml～100ml, there is quick promotion Farrowing, shorten the effect of stages of labor, rehabilitation after favourable Farrowing, improves pig premunition, ensures piglet survival rate, improve the price of deed, be a kind of have can replace existing antibiotic animal feed additive.Wherein, sow be take 100ml consumption as best.
embodiment 3
3.1 test material
3.1.1 experimental animal and feed
3.1.1.1sow perinatal period is used in test: be grow up (binary is assorted).
Basal diet:
Sow: daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.
Corn, fish meal, dregs of beans, wheat bran, trace element.Hunan Xiang Jiuyang feed corporation,Ltd.
for reagent product and reagent
3.1.2.1the compound premix group (solid-state) of the quick childbirth of sow and postpartum recovery: be that Hu'nan Sunaccord Biological Technical Co., Ltd.'s research and development are produced.
Prescription: by weight percentage, it consists of following component: thymic extract 20%, rabbit flesh extract 15%, brown sugar 20%, potassium sorbate 0.5%, water 44.5%, compound premix by the quick childbirth of sow and postpartum recovery stirs than 1:1 with daily ration, dries.
Profit high (Lincomycin Hydrochloride, Spectinomycin Sulfate soluble powder): Suzhou animal health Co., Ltd of Pfizer.
test method
3.2.1 test grouping and processing
3.2.1.1animal used as test grouping:
To test with sow binary assorted (long white, great Bai), 10 every group, be divided at random 4 groups, the close collocation of parity is (2-3 tire) evenly, and the close collocation of body weight is even.
Test method
The design of employing single factor experiment, investigates 6 months continuously, and test pig is divided into 4 groups at random, and the scheme of specifically dividing into groups is as follows:
A. antibiotic control group: basal diet+sharp high consumption per day
B.25g the quick compound premix group of childbirth and postpartum recovery of sow: basal diet+every the each 25g sow of sow is the compound premix of childbirth and postpartum recovery fast
C.50g the quick compound premix group of childbirth and postpartum recovery of sow: basal diet+every the each 50g sow of sow is the compound premix of childbirth and postpartum recovery fast
D.100g the quick compound premix group of childbirth and postpartum recovery of sow: basal diet+every the each 100g sow of sow is the compound premix of childbirth and postpartum recovery fast
It is experimental subjects that perinatal period sow is take in this test, and daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.By above-mentioned grouping, feed respectively.14 days experimental periods.When the beginning of experimental period, to test pig parity, the close overbit of beating of body weight, and carry out homogeneity test, indivedual adjustment makes group difference not remarkable (P>0.05).
grouping and dosage setting foundation
In above-mentioned test, all set three sows fast the compound premix group dosage level of childbirth and postpartum recovery do parallel test, and set an antibiotic medicine control group.The basis of design of the compound premix test group dosage of the quick childbirth of sow and postpartum recovery is, with reference to preliminary prerun in early stage, set sow RD 50g, then take RD as middle dosage, each increases and reduces 1 times, has set high dose 100g and low dosage 25g.
observe
Duration of test, observes spirit, appetite, activity, the ight soil situation of pig every day, and makes a record, stages of labor, sow morbidity in postpartum head, farrowing pig's head number, piglet cradling room morbidity head while recording the antenatal morbidity head of sow, Farrowing simultaneously.
result of the test:in Table 3.
Table 3:
the impact of different disposal on sow production performance
25,50,100g sow feed perinatal period additive experimental group and the comparison of antibiotic control group presentation of results:, the antenatal incidence of disease B of sow, C, D experimental group are lower than antibiotic control group A; Stages of labor: experiment B, C, D group are significantly less than control group A, shorten stages of labor 0.6～1.5 hour; Sow appetite recovery time in postpartum: experiment B, C, D group are less than control group A.The piglet incidence of disease: experiment C, D group are less than experiment B group and control group A.
In sum: data show, add patented product of the present invention: sow feeding amount 25g～100g, there is quick promotion Farrowing, shorten the effect of stages of labor, be conducive to sow rehabilitation, improve pig premunition, ensure piglet survival rate, improve the price of deed, be a kind of have can replace existing antibiotic animal feed additive.Wherein, sow be take 100g consumption as best.
embodiment 4.
4.1 test material
4.1.1 experimental animal and feed
4.1.1.1sow perinatal period is used in test: be grow up (binary is assorted).
Basal diet:
Sow: daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.
Corn, fish meal, dregs of beans, wheat bran, trace element.Hunan Zheng Hong development in science and technology Co., Ltd.
for reagent product and reagent
4.1.2.1feed additive for sows in perinatal period (liquid state): for Hu'nan Sunaccord Biological Technical Co., Ltd.'s research and development are produced.
Prescription: by weight percentage, it consists of following component: thymic extract 12%, rabbit flesh extract 7.5%, brown sugar 20%, potassium sorbate 0.5%, water 60%.
0.2% composite premixed feed for pigs (liquid state): for Hu'nan Sunaccord Biological Technical Co., Ltd. produces.(prescription: Cobastab
10.3%, Cobastab
20.4%, ZnSO
4 .7H
2o 6%)
4.2 test method
4.2.1 test grouping and processing
4.2.1.1animal used as test grouping:
To test with sow binary assorted (long white, great Bai), 10 every group, be divided at random 4 groups, the close collocation of parity is (3-5 tire) evenly, and the close collocation of body weight is even.
Test method
The design of employing single factor experiment, is divided into 4 groups at random by test pig, and the scheme of specifically dividing into groups is as follows:
A. vitamin(e) B group control group: the daily 100ml of basal diet+0.2% composite premixed feed for pigs (liquid state)
B. group I: the daily 100ml+ sow of basal diet+0.2% composite premixed feed for pigs (liquid state) is the compound premix 100ml of childbirth and postpartum recovery fast, feeds in antenatal 1 day to 1 day postpartum, and all the other times are pressed control group fed.
C. experimental group II: the daily 100ml+ sow of basal diet+0.2% composite premixed feed for pigs (liquid state) is the compound premix 100ml of childbirth and postpartum recovery fast, feeds in antenatal 3 days to 2 days postpartum.All the other times are pressed control group fed.
D. experimental group III: the daily 100ml+ sow of basal diet+0.2% composite premixed feed for pigs (liquid state) is the compound premix 100ml of childbirth and postpartum recovery fast, feeds in antenatal 7 days to 3 days postpartum, and all the other times are pressed control group fed.
It is experimental subjects that perinatal period sow is take in this test, and daily ration designs with reference to NRC(1998) pig nutritional need and Chinese Pigs feeding standard.By above-mentioned grouping, feed respectively.Experimental period, is respectively 14 days.When the beginning of experimental period, to test pig parity, the close overbit of beating of body weight, and carry out homogeneity test, indivedual adjustment makes group difference not remarkable (P>0.05).
grouping and dosage setting foundation
In above-mentioned test, all set three experiment feeding time levels and done parallel test, and set a vitamin(e) B group control group.The basis of design of the compound premix dosage of the quick childbirth of sow and postpartum recovery is, with reference to pre-stage test, set sow optimal dose 100ml, then to investigate the impact of feeding time on sow stages of labor, sow rehabilitation duration, be designed to antenatal 1 day to 1 day postpartum, antenatal 3 days to 2 days postpartum, antenatal 7 days to 3 days postpartum.
observe
Duration of test, observes spirit, appetite, activity, the ight soil situation of pig every day, and makes a record, and stages of labor, sow morbidity in postpartum head, farrowing pig's head number, piglet cradling room morbidity head while recording the antenatal morbidity head of sow, Farrowing, in Table 4 simultaneously.
Sow rehabilitation duration is mainly investigated the detumescence of lochia efflux time, vaginal orifice and ecchymosis regression time, sow appetite recovery time, in Table 5.
result of the test:
Table 4:
the impact of different disposal on sow production performance
Presentation of results: each experimental group and the comparison of vitamin(e) B group control group, the antenatal incidence of disease of sow: experimental group II, experimental group III are lower than group I and Cobastab control group; Stages of labor: experimental group II, experimental group III are less than experiment I group and control group, difference is (P < 0.01) extremely significantly, shorten stages of labor more than 2 hours, group I is less than control group, difference is remarkable (P > 0.05) not, experimental group III and the comparison of experimental group II, experimental group III is better than experimental group II, and difference is remarkable (P > 0.05) not; Postpartum the sow incidence of disease: experiment I, II, III group are less than control group, and significant difference and difference is remarkable (P < 0.05, P < 0.01) extremely.The piglet incidence of disease: experiment I, II, III group are less than control group, significant difference and difference is (P < 0.05, P < 0.01) extremely significantly, and experiment III group and experiment II difference is remarkable (P > 0.05) not.
Table 5:
the impact of different feeding times on sow postpartum recovery
Presentation of results: each experimental group and the comparison of vitamin(e) B group control group, lochia efflux time: each experimental group is better than vitamin(e) B group control group, difference is (P < 0.01) extremely significantly, experimental group III and the comparison of experimental group II, experimental group III is better than experimental group II, and difference is remarkable (P > 0.05) not; Vaginal orifice detumescence and ecchymosis regression time: group I and control group difference is remarkable (P > 0.05) not, experimental group III and experimental group II are better than control group, difference is (P < 0.01) extremely significantly, and experimental group III and experimental group II difference is remarkable (P > 0.05) not; Sow appetite recovery time: each experimental group is better than vitamin(e) B group control group, difference is (P < 0.01) extremely significantly, and experimental group III and experimental group II difference is remarkable (P > 0.05) not.
In sum: data show, add patented product of the present invention: sow feeding amount 25ml～100ml, has the sow of promotion and give a birth fast, shorten stages of labor; Favourable sow postpartum recovery; Improve pig premunition, ensure piglet survival rate; Improve the price of deed, be a kind of have can replace existing antibiotic animal feed additive.Wherein, be best with vitamin(e) B group compatibility, consumption 100ml.
Claims (5)
1. for a compound premix for the quick childbirth of sow and postpartum recovery, it is characterized in that: by weight percentage, it consists of following component: thymic extract 1-25%, rabbit flesh extract 1-15%, brown sugar 5-25%, potassium sorbate 0.2-0.5%, water 34.5-92.8%; The preparation method of described rabbit flesh extract is as follows:
A. healthy rabbit is slaughtered, rapidly peeling, gets in the cold water that dorsal muscles and leg flesh sets to 0-4 ℃ or puts refrigerator freezing, rubbing;
B. alcohol is processed: the rabbit flesh of rubbing is put to 2-3 and doubly measure in ice ethanol, stir 30 minutes, filter, get filter residue and add 2-3 again and doubly measure ice ethanol, stir 30 minutes, merge ice ethanol filtrate for the first time, be heated to seethe with excitement 5 minutes, filter;
C. dissolve: get filter residue and put in the cold water of 0-4 ℃ of 2 times of amount, stir 30 minutes; Filtrate after filtration adds glacial acetic acid and adjusts pH value to 2.0-4.0, obtains rabbit flesh extract standby.
2. a kind of compound premix for the quick childbirth of sow and postpartum recovery as claimed in claim 1, is characterized in that: by weight percentage, it consists of following component: thymic extract 12%, rabbit flesh extract 7.5%, brown sugar 20%, potassium sorbate 0.5%, water 60%.
3. a kind of compound premix for the quick childbirth of sow and postpartum recovery as claimed in claim 1, is characterized in that: by weight percentage, it consists of following component: thymic extract 20%, rabbit flesh extract 15%, brown sugar 20%, potassium sorbate 0.5%, water 44.5%.
4. a kind of compound premix for the quick childbirth of sow and postpartum recovery as claimed in claim 1, is characterized in that: described thymic extract refers to the peptide material extracting from ox, pig, chicken animal thymus.
5. a kind of for the quick compound premix of childbirth and postpartum recovery of sow as described in claim 1 or 2 or 3, is characterized in that: the step of preparation process of this compound premix is as follows:
A. the preparation of thymic extract:
A. get healthy animal thymus gland and thaw, degrease, rubs;
B. hydrolysis: the water of 1 kilogram of thymus gland amount of doubling, heat to 40-60 ℃, add complex enzyme 2000-3000 U, add 40% sodium hydroxide solution and adjust pH value to 7.5-9.0, enzymolysis 10hr;
C. deactivation: get hydrolyzate, be heated to 100 ℃, be incubated 10 minutes, obtain thymic extract, put in closed container, cooling standby;
B. the preparation of rabbit flesh extract:
A. healthy rabbit is slaughtered, rapidly peeling, gets in the cold water that dorsal muscles and leg flesh sets to 0-4 ℃ or puts refrigerator freezing, rubbing;
B. alcohol is processed: the rabbit flesh of rubbing is put to 2-3 and doubly measure in ice ethanol, stir 30 minutes, filter, get filter residue and add 2-3 again and doubly measure ice ethanol, stir 30 minutes, merge ice ethanol filtrate for the first time, be heated to seethe with excitement 5 minutes, filter;
C. dissolve: get filter residue and put in the cold water of 0-4 ℃ of 2 times of amount, stir 30 minutes; Filtrate after filtration adds glacial acetic acid and adjusts pH value to 2.0-4.0, obtains rabbit flesh extract standby;
C. allotment: get thymic extract, rabbit flesh extract, brown sugar, potassium sorbate and water and prepare in proportion, after filtering, packing gets product.
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| CN104431542A (en) * | 2014-12-12 | 2015-03-25 | 遵义市金鼎农业科技有限公司 | Health-function feed for postpartum sows |
| CN105918674A (en) * | 2016-05-16 | 2016-09-07 | 栾文华 | Composite premix for sows in perinatal period |
| CN106562064B (en) * | 2016-11-14 | 2020-08-21 | 广州农宝饲料有限公司 | Lactating sow concentrated feed suitable for wet mixing feeding and preparation method thereof |
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| CN102246909B (en) * | 2010-06-21 | 2012-12-26 | 北京科兴大地饲料有限公司 | Special healthcare feed for perinatal milk cows and preparing method thereof |
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