CN101999553B - Feed additive for controlling livestock sand crack - Google Patents
Feed additive for controlling livestock sand crack Download PDFInfo
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- CN101999553B CN101999553B CN2010105895791A CN201010589579A CN101999553B CN 101999553 B CN101999553 B CN 101999553B CN 2010105895791 A CN2010105895791 A CN 2010105895791A CN 201010589579 A CN201010589579 A CN 201010589579A CN 101999553 B CN101999553 B CN 101999553B
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- biotin
- zinc
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- 239000004576 sand Substances 0.000 title claims abstract description 33
- 244000144972 livestock Species 0.000 title abstract 4
- 239000003674 animal food additive Substances 0.000 title abstract 2
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 56
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims abstract description 36
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 34
- 229960002685 biotin Drugs 0.000 claims abstract description 28
- 235000020958 biotin Nutrition 0.000 claims abstract description 28
- 239000011616 biotin Substances 0.000 claims abstract description 28
- 239000000843 powder Substances 0.000 claims abstract description 24
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims abstract description 18
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 18
- 229960000304 folic acid Drugs 0.000 claims abstract description 18
- 235000019152 folic acid Nutrition 0.000 claims abstract description 18
- 239000011724 folic acid Substances 0.000 claims abstract description 18
- 229940055726 pantothenic acid Drugs 0.000 claims abstract description 18
- 235000019161 pantothenic acid Nutrition 0.000 claims abstract description 18
- 239000011713 pantothenic acid Substances 0.000 claims abstract description 18
- AZJQQNWSSLCLJN-UHFFFAOYSA-N 2-ethoxyquinoline Chemical compound C1=CC=CC2=NC(OCC)=CC=C21 AZJQQNWSSLCLJN-UHFFFAOYSA-N 0.000 claims abstract description 16
- HJSYJHHRQVHHMQ-TYYBGVCCSA-L zinc;(e)-but-2-enedioate Chemical compound [Zn+2].[O-]C(=O)\C=C\C([O-])=O HJSYJHHRQVHHMQ-TYYBGVCCSA-L 0.000 claims abstract description 14
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims description 28
- 241001465754 Metazoa Species 0.000 claims description 20
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical group [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 18
- 239000011701 zinc Substances 0.000 claims description 18
- 229910052725 zinc Inorganic materials 0.000 claims description 18
- 229910021536 Zeolite Inorganic materials 0.000 claims description 6
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical group O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims description 6
- 239000010457 zeolite Substances 0.000 claims description 6
- 239000000654 additive Substances 0.000 abstract description 16
- 230000000996 additive effect Effects 0.000 abstract description 16
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- 241000282887 Suidae Species 0.000 abstract description 4
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- 208000014770 Foot disease Diseases 0.000 abstract 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 abstract 1
- 229930003471 Vitamin B2 Natural products 0.000 abstract 1
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- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 4
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- 239000004519 grease Substances 0.000 description 2
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- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 description 2
- 206010020718 hyperplasia Diseases 0.000 description 2
- 238000011835 investigation Methods 0.000 description 2
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- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 description 1
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 1
- 101710146995 Acyl carrier protein Proteins 0.000 description 1
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- 108010078791 Carrier Proteins Proteins 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 244000000626 Daucus carota Species 0.000 description 1
- 235000002767 Daucus carota Nutrition 0.000 description 1
- 102000002322 Egg Proteins Human genes 0.000 description 1
- 108010000912 Egg Proteins Proteins 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010017577 Gait disturbance Diseases 0.000 description 1
- 208000032843 Hemorrhage Diseases 0.000 description 1
- 240000008415 Lactuca sativa Species 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 206010025476 Malabsorption Diseases 0.000 description 1
- 208000004155 Malabsorption Syndromes Diseases 0.000 description 1
- PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
- 102000016943 Muramidase Human genes 0.000 description 1
- 108010014251 Muramidase Proteins 0.000 description 1
- 206010073713 Musculoskeletal injury Diseases 0.000 description 1
- 231100000678 Mycotoxin Toxicity 0.000 description 1
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- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 206010000269 abscess Diseases 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
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- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
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- 230000037396 body weight Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
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- 238000004364 calculation method Methods 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003026 cod liver oil Substances 0.000 description 1
- 235000012716 cod liver oil Nutrition 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
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- 230000006378 damage Effects 0.000 description 1
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- 230000035617 depilation Effects 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 210000000969 egg white Anatomy 0.000 description 1
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- 238000005516 engineering process Methods 0.000 description 1
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- 125000001924 fatty-acyl group Chemical group 0.000 description 1
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- 230000035558 fertility Effects 0.000 description 1
- 210000003194 forelimb Anatomy 0.000 description 1
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- 238000010438 heat treatment Methods 0.000 description 1
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- 229910052742 iron Inorganic materials 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
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- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 239000002636 mycotoxin Substances 0.000 description 1
- 210000000282 nail Anatomy 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
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- 229960002748 norepinephrine Drugs 0.000 description 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 description 1
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/70—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in livestock or poultry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention relates to a feed additive for controlling livestock sand crack, which comprises the following raw materials in percent by weight: 18-21 percent of fat powder, 6-8 percent of zinc fumarate, 1-3 percent of biotin, 0.3-0.5 percent of vitamin B2, 0.2-0.3 percent of pantothenic acid, 0.2-0.3 percent of folic acid, 0.08-0.2 percent of ethoxy quinoline and 68-72 percent of carrier. 0.2 percent of additive is added in the daily base feed of pigs, thus the incidence rate of noncommunicable and nontransmissible livestock limb and foot diseases can be remarkably reduced, and the sand crack disease of the livestock can be effectively treated.
Description
Technical field
The invention belongs to the feed stripped technical field, be specifically related to a kind of feed addictive that can prevent and treat the domestic animal sand crack, solve the problem of domestic animal sand crack.
Background technology
Along with the raising of boar seed selection degree, the pig back fat is more and more thinner, the speed of growth is more and more faster, fertility is more and more higher, build is constantly improved, but has also caused series of problems, and sand crack namely is one of them.Market pig generation cracked feet generally just realized at the middle and late growth stage or before closing on listing, although market pig seldom because sand crack is eliminated, sand crack can make that its speed of growth slows down, feed intake reduces, the Time To Market prolongation, the loss that brings thus can not be underestimated.Rough calculation, if market pig postpones 10 days because cracked feet causes Time To Market, the loss of every pig just can be up to 60～80 yuan.
Sand crack is a global question, and the reason that causes its generation is many-sided, but main cause is owing to the various nutrients shortage causes, such as calcium phosphorus deficiency, manganese deficiency, scarce zinc, scarce vitamin D, scarce biotin etc.And mycotoxin can cause the vitamin incomplete absorption, causes the shortages such as biotin, vitamin D; The biotin addition is inadequate; Trace element zinc absorbs not, the absorption of Calcium in Feed, iron, the too high antagonism zinc of copper, and the too high antagonism zinc of calcium absorbs in the drinking-water that has; Fat adds not in the feed, causes vitamin A or D incomplete absorption, and Calcium and phosphorous absorption is inadequate, the keratinization insufficient strength; Illumination is inadequate, and vitamin D transforms not, affects Calcium and phosphorous absorption etc., and above-mentioned factor all can cause sand crack.In addition, domestic animal kind, feeding environment etc. also can cause the generation of cracked feet.
At present, for the sand crack that nongenetic, non-feeding environment factor cause, the remedial measure of taking is generally: in seasonal frequently-occurring disease early stage, such as autumn and winter handing-over period, add 200～250mg biotin in feed per ton, to prevent sand crack.As falling ill, the biotin addition can increase by 1～1.5 times, to increasing and decreasing according to circumstances more by the end of January.For dry and cracked coffin, smear cod-liver oil every day 1～2 time, the pig that falls ill the simultaneously 0.5kg carrot of feeding every day is added 1% grease in the mixed feed, to curing cracked feet certain booster action is arranged.Sand crack treatment measure in the production: a bag biotin+compound vitamin+ZnSO
4Spice, injection of antibiotics diminishes inflammation simultaneously.Perhaps utilize existing on the market " care of feed precious " series products blindly to replenish biotin (but fact proved that having added the biotin domestic animal still can sand crack) to pig.Above-mentioned measure is more single, is simple additional a certain element, can not fundamentally solve the sand crack problem.
Summary of the invention
The object of the invention is to provide a kind of feed addictive of preventing and treating the domestic animal sand crack, solves the problem of domestic animal (especially boar, market pig) sand crack.
For achieving the above object, the present invention adopts following technical scheme:
A kind of feed addictive of preventing and treating the domestic animal sand crack, it comprises the raw material of following percentage by weight:
Fatty powder 18～21%
Zinc fumarate 6～8%
Biotin 1～3%
Cobastab
20.3～0.5%
Pantothenic acid 0.2～0.3%
Folic acid 0.2～0.3%
Ethoxyquinoline 0.08～0.2%
Carrier 68～72%.
Described fatty powder is feed grade fatty powder (wherein the quality percentage composition of fat is 40,45 or 50%), and described zinc fumarate is the feed grade zinc fumarate, and described biotin is feed grade biotin (the quality percentage composition of biotin is 2%), described Cobastab
2Be the feed grade Cobastab
2(Cobastab
2The quality percentage composition be 80%), described pantothenic acid is feed grade pantothenic acid (the quality percentage composition of pantothenic acid is 90%), described folic acid is feed grade folic acid (the quality percentage composition of folic acid is 95%), described ethoxyquinoline is the feed grade ethoxyquinoline.
Preferably, the quality percentage composition of fat is 50% in the described feed grade fatty powder; The quality percentage composition of zinc is 36% in the described feed grade zinc fumarate, and the quality percentage composition of ethoxyquinoline is 30% in the described feed grade ethoxyquinoline.
Described carrier is preferably zeolite powder and/or litter shell powder.
The preparation method of additive of the present invention: with biotin, folic acid, pantothenic acid, Cobastab
2, ethoxyquinoline and 1/2 carrier mixing get mixture a; Then zinc fumarate and remaining 1/2 carrier mixing are got mixture b; At last fatty powder and mixture a and b are fully mixed, get final product.Annotate: finished product 100% is by 40 orders.
The usage and dosage of additive of the present invention: cooperate the basic diet of domestic animal to use together, addition is 0.2% of basic diet weight, can play the effect of prevention and treatment sand crack.
The function of each component of the present invention:
Fatty powder: provide capacity essential aliphatic acid, the facilitation that linoleic acid is certain to being absorbed with of biotin.
Organic zinc: sow is inadequate to malabsorption or the Zinc in Feed element addition of zinc element, can cause sand crack or side to split.When boar lacks zinc, do not satisfy skin, hoof keratinization process to the needs of zinc, occur typical sand crack symptom yet, especially the breeding season boar, symptom is even more serious.On the market in the commodity pig's mixed feed zinc content be 52.92ppm, suppose every pig feed 3kg of searching for food every day, day taking in a zinc amount is 158.76mg, also just normally needs 53% of zinc amount.Through the test of Jiangsu Agricultural College experimental center, be 163.75ppm by the hair zinc content when boar is normal, only have 130.9ppm when suffering from cracked feet.The zinc that the present invention adds is zinc fumarate, and is higher than the absorption rate of inorganic zinc.
Biotin: being that animal body is kept the necessary low molecule organic matter of normal physiological function, is the indispensable nutriment of animal body.When long-term lacking or famine biotin, because not keeping cuticula intensity and the hardness of hoof, the hoof tips qualitative change is soft, and very easily wearing and tearing can cause the coffin be full of cracks, and hoof transverse fissure and foot pad crack are also hemorrhage, sometimes have the symptoms such as rear foot spasm, depilation and inflammation.According to investigations, the pig on many national pig farms has the situation of egg-white injury, the biotin that contains effective value in its feed is too low, cause that the hoof tips qualitative change is soft, easy to wear, it is coarse to add pigsty floor, thereby cause cracked feet, breach then can occur and infect, occur when serious walking lamely, particularly intensive airtight feed lacks motion and this disease of the easier generation of solar radiation.Biotin has certain effect to cuticula intensity and the hardness of keeping hoof, and is relevant with limb hoof tips materialization and hoof integrality.Its participates in carbohydrate, lipid, protein and the nucleic acid metabolism of body, and participates in the metabolic processes such as other nutriments such as Methyl transporters reaction, also with the function of lysozyme activation and sebaceous glands, and Cobastab
6, folic acid, pantothenic acid metabolism closely related.Dry weather, temperature shakiness, sow is for the variation that conforms, and the body surface capillary shrinks, because the biotin metabolism occurs unusually, causes normal lipid material to be secreted and reduces, and it is thin tender that coffin becomes.Fat in the daily ration, folic acid, pantothenic acid, Cobastab
12Cobastab
6Deng all closely related with absorption and the metabolism of biotin.
Cobastab
2: have the growth of promotion and cytothesis; Promote the normal growths such as skin, nail, hair; The function of protection skin follicle mucous membrane and sebaceous glands; Also be protein, sugar, fatty acid metabolism and energy utilization and the necessary material of composition, can protect the health of skin.Cobastab in the body
2Storage be extremely limited, therefore need in the feed of every day, provide.Cobastab
2Easily by photo damage, in alkaline solution heating also easily destroyed be the main cause that causes its loss.
Pantothenic acid: play an important role in a lot of metabolic processes, it is essential for synthetic, the amino acid whose oxidative degradation of synthetic and degraded, the membrane phospholipid (comprising sphingolipid) of aliphatic acid.The major physiological activity form of pantothenic acid is coacetylase and acyl carrier protein, and their metabolic function is as acetyl group or fatty acyl group carrier.Pantothenic acid helps to form cell in vivo, is fat and sugar class indispensable material when being transformed into energy.In addition, can also resist stress, anti-infective, prevent some antibiotic toxicity.
Folic acid: be a kind of water-soluble B family vitamin, all most important to the multiple physical body metabolic processes, people's somagenic need with its erythroblast, norepinephrine and salad holder peaceful (neural chemical composition) in next life.Show that according to contemporary Chinese medical journal data people's pregnancy period Supplement of folic acid can prevent neonate's actinal surface to split.Use folic acid can promote this mechanism of skin health, the present invention adds this vitamin to promote the product effect.
Beneficial effect of the present invention:
Additive of the present invention is rich in the required various nutrients of domestic animal (such as grease, vitamin and organic trace element etc.), and reasonable mixture ratio science, provide the good growth such as domestic animal skin, cuticula, hair follicle, sebaceous glands the nutritive and health protection components required with Function, can effectively prevent and treat the domestic animal sand crack, High-efficient Production for boar provides basic guarantee, the stealthy economic loss of effectively avoiding market pig to cause because of sand crack.
The specific embodiment
Embodiment 1-3
A kind of feed addictive of preventing and treating the domestic animal sand crack, it each raw material weight percentage that comprises sees Table 1:
Above-mentioned fatty powder is feed grade fatty powder (wherein the quality percentage composition of fat is 50%), zinc fumarate is feed grade zinc fumarate (the quality percentage composition of zinc is 36%), biotin is feed grade biotin (the quality percentage composition of biotin is 2%), Cobastab
2Be the feed grade Cobastab
2(Cobastab
2The quality percentage composition be 80%), pantothenic acid is feed grade pantothenic acid (the quality percentage composition of pantothenic acid is 90%), folic acid is feed grade folic acid (the quality percentage composition of folic acid is 95%), and described ethoxyquinoline is feed grade ethoxyquinoline (the quality percentage composition of ethoxyquinoline is 30%).
Wherein carrier is zeolite powder among the embodiment 1, and carrier is litter shell powder among the embodiment 2, and carrier is the mixture that zeolite powder and litter shell powder form among the embodiment 3.
Take embodiment 1 as example, the preparation method of feed addictive of the present invention is described in detail in detail: with biotin, folic acid, pantothenic acid, Cobastab
2, ethoxyquinoline and 1/2 zeolite powder mixing get mixture a; Then zinc fumarate and remaining 1/2 zeolite powder mixing are got mixture b; At last fatty powder and mixture a and b are fully mixed, get final product.Annotate: finished product 100% is by 40 orders.
Usage and dosage: cooperate the basic diet of domestic animal to use together, addition is about 0.2% of basic diet weight.
The application test 1 that the prevention pig's feet splits
1, materials and methods
1.1 experimental design
Choose from Henan, Henan Superfriend Science ﹠ Technology Co., Ltd. subordinate proving ground Xiong Feng Si lattice boar Co., Ltd that body condition is good, age in days is consistent, 300 of body weight 80kg left and right sides replacement gilts, be divided at random two groups (being test group and control group), process 10 repetitions for every group, each repeats 15 pigs.Free choice feeding drinking-water.The contrast test design is adopted in this test, and experimental period, the duration of test feeding and management was carried out according to the conventional feeding and management of sow from reserve phase to the triplet.Result of the test sees Table 3.
1.2 test daily ration
With reference to NRC(1998) and Chinese Pigs trophic level (2004) preparation be used for feeding sow reserve phase, the gestational period and lactation period the basis diet.In the different production phases of sow, control group and test group corresponding reserve phase basis diet, the gestational period basis diet and basis diet lactation period (main distinction of two groups of basis diets be test group with alternative 0.2% wheat bran of 0.2% embodiment, 1 additive) of feeding respectively.Wherein, the premix in the reserve phase basis diet is SB34A; Premix in the diet of gestational period basis is SB54; Premix in the diet of lactation period basis is SB64.Each raw material weight percentage of the basic diet that the sow different times is fed sees table 2 for details.
Three kinds of products of premix SB34A, SB54 and SB64 are produced by Henan Superfriend Science ﹠ Technology Co., Ltd., and production licence number is for raising pre-(2009) 1454.The SB34A authentication code is that pre-word (2010) 026002 is raised in Henan; The SB54 authentication code is that pre-word (2010) 026004 is raised in Henan; The SB64 authentication code is that pre-word (2010) 026005 is raised in Henan.
1.3 investigation index
1.3.1 long hoof, wide hoof, volume hoof, the low hoof of sleeping system, prominent be high hoof, outer the make a slip incidence of the distortion hoof such as hyperplasia at the bottom of hoof, sand crack, the hoof.
The incidence of the distortion such as " 1.3.2 X " type limb, " O " type limb limb.
1.3.3 become the incidence of the non-infectious distortion hoof such as soft tissue injury, bone wound, nerve muscular paralysis disease, purulent inflammation, rheumatic arthritis, paralysis.
Results and analysis
2.1 add behind the additive of the present invention impact on sow limb hoof disease incidence
The basic diet of test group and control group pig is compared, and has added 0.2% additive of the present invention in the former the basic diet.As can be seen from Table 3, the distortion hoof incidence of test group pig is starkly lower than control group, illustrates in basic diet to add additive of the present invention, helps to reduce the trend of hyperplasia at the bottom of sow sand crack and the hoof.In addition, test group pig " X " or " O " type limb incidence are a little less than control group, but two groups difference is little.The incidence of the non-infectious distortion hoof of test group is starkly lower than control group, illustrate that additive of the present invention has the trend of the non-infectious distortion hoof of obvious reduction sow incidence, especially remarkably productive aspect reduction postpartum paralysis of sow, musculoskeletal injuries and purulent inflammation.
By above-mentioned result of the test as can be known, in the daily basic diet of pig, add 0.2% additive of the present invention, can significantly reduce non-infectious and incidence nongenetic boar limb hoof disease, illustrate that additive of the present invention can play the effect of prevention domestic animal sand crack.
The application test 2 that the treatment pig's feet splits
1, materials and methods
1.1 experimental design
Male peak plant selects 2～3 parity, suffers from 24 of the sows of sand crack from Qixian County, Henan Superfriend Science ﹠ Technology Co., Ltd. subordinate proving ground, is divided at random 4 groups (being control group, test group 1, test group 2 and test group 3), 6 every group.
Experimental period, finish from breeding beginning to wean.Raise according to the normal sow feeding manner in pig farm, day feeds three times, freely drinks water; The unification of preventive care program is carried out.Result of the test sees Table 5.
1.2 test daily ration
Each the raw material weight percentage of basic diet of feeding that extremely weaned at sow gestation 0-90 days, pregnant 91 days sees table 4 for details.(main distinction of four groups of basis diets is test group 1, test group 2 and test group 3 substitute respectively corresponding proportion with 0.1%, 0.2% and 0.3% embodiment, 1 additive wheat bran).Wherein, the premix of basis in the diet in pregnant 0-90 days is SB54; The gestation premix to the basic diet that weans in 91 days is SB64.
1.3 clinical symptoms and curative effect determinate standard:
Clinical symptoms: main manifestations is that slight crack different in size occurs for hoof face/page or leaf section, and the slight crack that has is not only thick but also long, through coronet to hoof at the bottom of.Slight crack betides the one or both sides (the simultaneous phenomenon of four limbs is few) of forelimb or hind leg, and is in the majority with hind leg.Sick pig walks lamely, and affected part is felt pain even severe pain, difficulty in walking, and the inconvenience that rises and retires, severe patient joint wearing skin forms local abscess, festers.Most sick pigs are the posture of searching for food of lying prostrate because not standing, and appetite is normal.Temperature check is not high.
Curative effect determinate standard: taking a turn for the better shows as hoof and still can see slight crack, shortens, shoals but compare before slight crack and the treatment; Cure and show as above-mentioned clinical symptom disappearance; Invalidly show as above-mentioned clinical symptoms and do not alleviate or increase the weight of.Efficient is cure rate and improvement rate sum.
Results and analysis
Each group of test group is compared with the basic diet of control group sow, has added the additive of the present invention of different content in the former the basic diet.As can be seen from Table 5, the control group sow is efficient to be 0, and test group 1, the efficient of 2 and 3 sow sand cracks are 100%, are far superior to the result of the test of control group.Illustrate that additive of the present invention can treat the sand crack symptom of domestic animal, and effect is remarkable.In addition, the curative effect of additive according to the present invention, and in conjunction with input cost, cost performance is best when adding 0.2% in basic diet.
In summary, additive of the present invention can effectively prevent and treat the domestic animal sand crack.
Claims (4)
1. a feed addictive of preventing and treating the domestic animal sand crack is characterized in that, is comprised of the raw material of following percentage by weight:
Fatty powder 18～21%
Zinc fumarate 6～8%
Biotin 1～3%
Cobastab
20.3～0.5%
Pantothenic acid 0.2～0.3%
Folic acid 0.2～0.3%
Ethoxyquinoline 0.08～0.2%
Carrier 68～72%.
2. feed addictive according to claim 1 is characterized in that, described fatty powder is the feed grade fatty powder, and described zinc fumarate is the feed grade zinc fumarate, and described biotin is the feed grade biotin, described Cobastab
2Be the feed grade Cobastab
2, described pantothenic acid is feed grade pantothenic acid, and described folic acid is feed grade folic acid, and described ethoxyquinoline is the feed grade ethoxyquinoline.
3. feed addictive according to claim 2 is characterized in that, the quality percentage composition of fat is 50% in the described feed grade fatty powder; The quality percentage composition of zinc is 36% in the described feed grade zinc fumarate, and the quality percentage composition of ethoxyquinoline is 30% in the described feed grade ethoxyquinoline.
4. according to claim 1 to 3 arbitrary described feed addictives, it is characterized in that described carrier is zeolite powder and/or litter shell powder.
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| CN102763776B (en) * | 2012-07-27 | 2013-12-11 | 太仓安佑生物科技有限公司 | Functional feed for promoting hoof health of breeding stock |
| CN103099068A (en) * | 2013-03-07 | 2013-05-15 | 江西正邦科技股份有限公司 | Pregnant sow feed capable of reducing sow sand crack |
| CN104366148A (en) * | 2014-12-12 | 2015-02-25 | 福建傲农生物科技集团有限公司 | Replacement-gilt feed additive and application thereof |
| CN104431606A (en) * | 2014-12-19 | 2015-03-25 | 天津正大饲料科技有限公司 | Concentrated feed for improving breeding effect of replacement gilts and preparation method of concentrated feed |
| CN104397496A (en) * | 2014-12-23 | 2015-03-11 | 广西商大科技有限公司 | Nutritional premixing agent and sow feed for improving sow foot and limb diseases |
| CN105497072B (en) * | 2015-11-05 | 2020-03-13 | 吉林农业大学 | Medicine blanket for preventing and treating pig split hoof disease |
| CN105433001A (en) * | 2015-12-11 | 2016-03-30 | 安徽安泰农业开发有限责任公司 | Dietotherapy composition for preventing swine limb and foot diseases |
| CN110916001A (en) * | 2019-12-13 | 2020-03-27 | 辽宁农业职业技术学院 | Feed additive for preventing and controlling foot and limb diseases of barn-fed sheep and preparation method thereof |
| CN111011592A (en) * | 2019-12-31 | 2020-04-17 | 斯卡恩动物保健品(商丘)有限公司 | Feed additive for treating sow hoof cracking and preparation and application thereof |
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| CN101040672A (en) * | 2007-04-07 | 2007-09-26 | 乐建来 | Multidimensional feed additive for sow |
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Denomination of invention: A feed additive for preventing and treating livestock hoof cracking Effective date of registration: 20231208 Granted publication date: 20130403 Pledgee: Bank of China Zhengzhou Huayuan Branch Pledgor: HENAN XIONGFENG TECHNOLOGY CO.,LTD. Registration number: Y2023980069980 |