CN108392449A - A kind of Khotan jade anti-aging lotion and preparation method thereof - Google Patents

A kind of Khotan jade anti-aging lotion and preparation method thereof Download PDF

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CN108392449A
CN108392449A CN201810511283.4A CN201810511283A CN108392449A CN 108392449 A CN108392449 A CN 108392449A CN 201810511283 A CN201810511283 A CN 201810511283A CN 108392449 A CN108392449 A CN 108392449A
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khotan jade
extract
aging
lotion
powder
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陈桂芳
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Guangdong Stone Microelement Research Institute (general Partnership)
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25Silicon; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9794Liliopsida [monocotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/412Microsized, i.e. having sizes between 0.1 and 100 microns
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Engineering & Computer Science (AREA)
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  • Inorganic Chemistry (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of Khotan jade anti-aging lotions and preparation method thereof to be made Khotan jade anti-aging lotion by the way that sedge extract, Japanese cryptotaenia stem and leaf extract, ginseng berry extract, ultra micro Khotan jade powder are carried out reasonable compatibility after scientific matching.The characteristics of anti-aging lotion of the present invention has naturally mildly, nonirritant, highly effective and safe, long-time service can effectively slow down aging.

Description

A kind of Khotan jade anti-aging lotion and preparation method thereof
Technical field
The present invention relates to cosmetic fields, and in particular to a kind of Khotan jade anti-aging lotion and preparation method thereof.
Background technology
Skin aging is to be determined by inherent cause and continued gradual physiology mistake by a kind of of a variety of such environmental effects Journey.Environmental pollution, the irradiation of long-time ultraviolet light and smoking can accelerate the ageing process of skin, lead to skin histology water shortage, cutin Layer be hardened, epidermis and skin corium are thinning, collagen fibers of skin reduce, melanin deposition, to generate wrinkle, skin become pine The problems such as relaxation, tarnish, color spot.With the improvement of people's life quality, anti-aging goes wrinkle increasingly to be paid close attention at people One problem.
Skin care item type is various on the market at present, and effect is different, including whitening, moisturizing, nti-freckle and anti-aging etc..But it is very much Product is more or less added to some irritation chemical substances, although these substances have short-term whitening to the skin of people, resist The skin care effects such as aging, but be used for a long time, skin can be made severely damaged instead, long acne, color spot and fat secretion occur The skin problems such as imbalance.Patent of invention CN201810040840.9 discloses a kind of anti-aging lotion, counts in parts by weight, including Following component:14.5-16.5 parts of moisturizer, 10.2-13.8 parts of emollient, 2.50-3.50 parts of peptides composition, skin conditioner 1.70-2.80 parts, 0.3-0.6 parts of thickener, 1.50-2.50 parts of emulsifier, 3.00-4.50 parts of other base-materials, surplus is water, Middle peptides composition be ginseng peptide, sea cucumber peptide and gadus peptide compound.The invention has certain senile-resistant efficacy, but former Expect that cost is higher.
Invention content
In order to solve the above-mentioned technical problem, the purpose of the present invention is to provide a kind of Khotan jade anti-aging lotion and its preparations Method, specific technical solution are as follows:
A kind of Khotan jade anti-aging lotion, includes the ingredient of following mass percent:
Sedge extract 1-5%, Japanese cryptotaenia stem and leaf extract 1-5%, ginseng berry extract 1-3%, ultra micro Khotan jade powder 1- 5%.
Preferably, the Khotan jade anti-aging lotion, includes the ingredient of following mass percent:
Sedge extract 2-4%, Japanese cryptotaenia stem and leaf extract 2-4%, ginseng berry extract 1.5-2.5%, ultra micro Khotan jade Powder 2-4%.
Preferably, the Khotan jade anti-aging lotion, includes the ingredient of following mass percent:
Sedge extract 3%, Japanese cryptotaenia stem and leaf extract 3%, ginseng berry extract 2%, ultra micro Khotan jade powder 3%.
Wherein, the preparation method of the ultra micro Khotan jade powder includes the following steps:
(1) it by Khotan jade particle, cleans, removal wherein impurity, low temperature drying;
(2) vibromill is added in the Khotan jade after removal of impurities and is ground into ultra-micro powder, grain size is less than 10 μm;
(3) gained powder being subjected to high temperature sintering 10min, temperature is at 600-800 DEG C, to remove mercury and arsenic therein, drop Temperature is up to ultra micro Khotan jade powder.
Khotan jade anti-aging lotion of the present invention further includes the ingredient of following mass percent:
Glycerine 2-10%, butanediol 1-8%, isopropyl palmitate 2-6%, caprylic/capric triglyceride 1-6%, 16 Alkyl octadecanol 2-4%, stearic acid 1-2%, sorb smooth stearate 1-2%, polysorbate -600.5-2%, acrylic acid Hydroxyl ethyl ester/sodium acryloyldimethyl taurate copolymers 0.5-1.5%, jojoba seed oil 1-3%, avocado oil 1-3%, hyalomitome Sour 0.02-0.05%, xanthans 0.01-0.03%, methyl hydroxybenzoate 0.02-0.1%, Bis(hydroxymethyl)imidazolidinyl urea 0.02- 0.1%, Nipasol 0.02-0.1%, deionized water surplus.
The preparation method of Khotan jade anti-aging lotion of the present invention, includes the following steps:
(1) isopropyl palmitate, caprylic/capric triglyceride, cetylstearyl alcohol, stearic acid, sorb is smooth hard Resin acid ester, polysorbate -60, jojoba seed oil, avocado oil, methyl hydroxybenzoate, Nipasol mixing are heated to 75~80 DEG C dissolving is complete, and A phases are made;
(2) by glycerine, butanediol, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, hyaluronic acid, Huang Virgin rubber, Bis(hydroxymethyl)imidazolidinyl urea, deionized water mixing are heated to 75~80 DEG C of dissolvings completely, and B phases are made;
(3) A being added to B phases, emulsifying homogeneous 3-5min, insulated and stirred 8-10min are to be mixed to be cooled to 40-45 DEG C, Sedge extract, Japanese cryptotaenia stem and leaf extract, ginseng berry extract, ultra micro Khotan jade is added in stirring under 500-800r/min rotating speeds Powder, homogeneous 1-2min are cooled to room temperature to get Khotan jade anti-aging lotion.
The effect of each material composition of the present invention, is described below:
Japanese cryptotaenia stem and leaf (Cryptotaeniajaponica Hassk) is that Umbelliferae (Umbelliferae) perennial herb is planted Object also known as the water-white root of Dahurian angelica, big flipper etc..Japanese cryptotaenia stem and leaf rich in carrotene, vitamin B1, vitamin B2, niacin, vitamin C, The multivitamins such as calcium, iron, zinc and minerals.Japanese cryptotaenia stem and leaf has good Antioxidation in vitro, to DPPH, O2- and OH free radicals all have good scavenging effect, can obviously inhibit external biological lipid peroxidation.Japanese cryptotaenia stem and leaf extract The inhibiting effect to biomembrane peroxidatic reaction of lipid not only show the spontaneous lipid peroxidation of biomembrane, but also table Now by the lipid peroxidation of the liver mitochondrion film of Fe2+-VitC inductions, show lipid of the Japanese cryptotaenia stem and leaf extract to biomembrane Peroxidating has extensive inhibiting effect.
Sedge (Carex meyeriana Kunth) is the herb of Cyperaceae sedge platymiscium, is the biography of warming dehumidifying Unite Chinese medicine, there is dispelling cold and dehumidification, promoting blood circulation and removing blood stasis, active pain relieving and other effects, promote blood circulation, activating cell, dispelling fatigue, The functions such as sterilize, build up health.By free amino acid extremely abundant contained in sedge, can by the body temperature of human body, It is less readily available for absorption by the skin, nutrition plays the role of good maintenance to skin.
Panax ginseng fruit is the green herbaceous plant of perennial semi-lignified, and it is the treasure in fruit to add Solanaceae, Solanum, also known as Jin Canguo Product, meat faint scent succulence have abundant nutritive value, are rich in amino acid, vitamin C, trace element and superoxide dismutase The ingredients such as enzyme SOD, saponin.Ginseng berry extract makes keratoderma have preferable, lasting moistening effect and white-skinned face function, It increases the aquation of skin itself, wakes up skin self-energy, reinforces the self-repairing capability of skin, black by supplying The enough nutrition of chromatophore activates the ability of its metabolism, to accelerate the normal catabolism of melanin, reaches whitening work With.
Khotan jade:One of Chinese four big name jade, main component SiO2, MgO, CaO and a small amount of FeO, have and promote blood Bad, enhancing metabolism, exclusion skin toxins are followed, radiation is kept out, and repairs skin damage cell and enhances cell viability Effect.
Compared with prior art, the present invention has the advantages that:
(1) sedge extract, Japanese cryptotaenia stem and leaf extract, ginseng berry extract are carried out reasonable compatibility by the present invention, and science is matched Khotan jade anti-aging lotion is made than after, wherein Japanese cryptotaenia stem and leaf all has good removing to DPPH, O2- and OH free radical Effect mitigates damage of the free radical to protein, DNA etc., slows down aging;Sedge have promote blood circulation, activating cell The effect of, while also containing abundant free amino acid, skin is maintained, is further slowed down aging;Panax ginseng fruit is by increasing skin The aquation of itself wakes up skin self-energy, reinforces the self-repairing capability of skin, accelerate the decomposition of melanin, reach Anti-aging purpose.Synergistic function can be generated between mentioned component, substantially increase the senile-resistant efficacy of lotion of the present invention.
(2) present invention also added ultra micro Khotan jade powder, and blood can be promoted to follow bad, enhancing metabolism, exclusion skin Toxin keeps out radiation, and repairs skin damage cell and enhance the effect of cell viability, slows down aging.
(3) the characteristics of product of the present invention has natural mild, nonirritant, highly effective and safe, long-time service can effectively prolong Slow aging.
Specific implementation mode
Below in conjunction with specific embodiment, the present invention is further elaborated.
The all the components title occurred in text is INCI (International Nomenclature Cosmetic Ingredient), i.e. international cosmetic raw material name institute is to defined title.
The formula of Khotan jade anti-aging lotion embodiment 1-5 of the present invention, is shown in Table 1.
Table 1
The preparation method of ultra micro Khotan jade powder includes the following steps in above-described embodiment 1-5:
(1) it by Khotan jade particle, cleans, removal wherein impurity, low temperature drying;
(2) vibromill is added in the Khotan jade after removal of impurities and is ground into ultra-micro powder, grain size is less than 10 μm;
(3) gained powder being subjected to high temperature sintering 10min, temperature is at 600-800 DEG C, to remove mercury and arsenic therein, drop Temperature is up to ultra micro Khotan jade powder.
The preparation method of above-described embodiment 1-5 Khotan jade anti-aging lotions includes the following steps:
(1) isopropyl palmitate, caprylic/capric triglyceride, cetylstearyl alcohol, stearic acid, sorb is smooth hard Resin acid ester, polysorbate -60, jojoba seed oil, avocado oil, methyl hydroxybenzoate, Nipasol mixing are heated to 75~80 DEG C dissolving is complete, and A phases are made;
(2) by glycerine, butanediol, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, hyaluronic acid, Huang Virgin rubber, Bis(hydroxymethyl)imidazolidinyl urea, deionized water mixing are heated to 75~80 DEG C of dissolvings completely, and B phases are made;
(3) A being added to B phases, emulsifying homogeneous 3-5min, insulated and stirred 8-10min are to be mixed to be cooled to 40-45 DEG C, Sedge extract, Japanese cryptotaenia stem and leaf extract, ginseng berry extract, ultra micro Khotan jade is added in stirring under 500-800r/min rotating speeds Powder, homogeneous 1-2min are cooled to room temperature to get Khotan jade anti-aging lotion.
Comparative example 1
Difference lies in be not added with sedge extract, other preparation methods and condition and 1 phase of embodiment with embodiment 1 Together.
Comparative example 2
Difference lies in be not added with Japanese cryptotaenia stem and leaf extract, other preparation methods and condition and 1 phase of embodiment with embodiment 1 Together.
Comparative example 3
Difference lies in be not added with ginseng berry extract, other preparation methods and condition and 1 phase of embodiment with embodiment 1 Together.
Comparative example 4
Difference lies in be not added with ultra micro Khotan jade powder, other preparation methods and condition and 1 phase of embodiment with embodiment 1 Together.
Embodiment 6
Elasticity of skin is tested
It is carried out to product prepared by embodiment 1-5 and comparative example 1-4, while by control group of a commercially available anti-aging lotion Detection result on probation.
Test object:Each experimental group is male 20 female 30 (25-50 Suis);Test zone:Face;Test equipment:Skin Skin elastic apparatus (Cutometer MPA 580).It uses:It used every 1 day 1 time, persistently uses 4 weeks;Test event:Skin elasticity.
Method:Environment on the day of subject tests after face cleaning in 23~25 DEG C of room temperature, relative humidity 50%-55% is sat quietly After 30min, looks steadily it and loosen facial muscle groups, gently close eyes.Its face is detected with skin elasticity instrument (Cutometer MPA 580) Portion's skin elasticity, probe is averaged in same tested region duplicate measurements 3 times when measurement.Test environment phase is kept when measurement To temperature, the influence of light, sound interference is avoided, using firmly wanting uniform when probe, the pressure of application should be constant.Subject Use the elasticity number for measuring tested region after 1 week, 2 weeks, 3 weeks, 4 weeks again.Terminate to measure, preserves data, finishing analysis data.
Test result and evaluation:
Before and after the tested region of subject uses product, elastic test value data analysis is relatively shown in Table 2.
Table 2
By the visible tested elasticity of skin variation of table 2 with the product time is used, gradually show a rising trend, by embodiment 1-5 with Comparative example 1-4 comparisons can obtain each ingredient collaboration of Khotan jade anti-aging lotion of the present invention and be more advantageous to enhancing elasticity of skin, Ke Yishi Now more obvious anti-aging effects, and lotion anti-aging effects of the present invention are apparently higher than commercial product.
Embodiment 7
Desalinate wrinkle test
Test object is above-mentioned 100 women, observe its use respectively 1-5 of the embodiment of the present invention, comparative example 1-4's and field After beautiful anti-aging lotion and commercially available anti-aging lotion 30d, on crow's feet or forehead microgroove there are situation, test result is shown in Table 3.
Table 3
As seen from Table 3, the Khotan jade anti-aging lotion of 1-5 of the embodiment of the present invention has significant desalination wrinkle effect, It is more preferable compared with comparative example 1-4 and commercially available anti-aging lotion effect.
Embodiment 8
Other measure of merit:
Still above-mentioned 100 women of test object, observe its use respectively 1-5 of the embodiment of the present invention, comparative example 1-4's and field After beautiful anti-aging lotion and commercially available anti-aging lotion 30d, skin improvement effects, test result is shown in Table 4.
Table 4
It can be obtained by table 4, the Khotan jade anti-aging lotion of 1-5 of the embodiment of the present invention is substantially better than skin improvement effects commercially available The lotion of anti-aging lotion and comparative example 1-4, freckle effect is notable, wherein the light spot effect of embodiment 1, moistening effect, promotion Skin humidity is best.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention Protect range.

Claims (6)

1. a kind of Khotan jade anti-aging lotion, which is characterized in that include the ingredient of following mass percent:Sedge extract 1- 5%, Japanese cryptotaenia stem and leaf extract 1-5%, ginseng berry extract 1-3%, ultra micro Khotan jade powder 1-5%.
2. Khotan jade anti-aging lotion as described in claim 1, which is characterized in that include the ingredient of following mass percent:
Sedge extract 2-4%, Japanese cryptotaenia stem and leaf extract 2-4%, ginseng berry extract 1.5-2.5%, ultra micro Khotan jade powder 2- 4%.
3. Khotan jade anti-aging lotion as claimed in claim 2, which is characterized in that include the ingredient of following mass percent:
Sedge extract 3%, Japanese cryptotaenia stem and leaf extract 3%, ginseng berry extract 2%, ultra micro Khotan jade powder 3%.
4. Khotan jade anti-aging lotion as described in claim 1, which is characterized in that further include following mass percent at Point:
Glycerine 2-10%, butanediol 1-8%, isopropyl palmitate 2-6%, caprylic/capric triglyceride 1-6%, cetyl Octadecanol 2-4%, stearic acid 1-2%, sorb smooth stearate 1-2%, polysorbate -600.5-2%, acrylic acid hydroxyl second Ester/sodium acryloyldimethyl taurate copolymers 0.5-1.5%, jojoba seed oil 1-3%, avocado oil 1-3%, hyaluronic acid 0.02-0.05%, xanthans 0.01-0.03%, methyl hydroxybenzoate 0.02-0.1%, Bis(hydroxymethyl)imidazolidinyl urea 0.02- 0.1%, Nipasol 0.02-0.1%, deionized water surplus.
5. Khotan jade anti-aging lotion as described in any one of claims 1-3, which is characterized in that the ultra micro Khotan jade powder Preparation method includes the following steps:
(1) it by Khotan jade particle, cleans, removal wherein impurity, low temperature drying;
(2) vibromill is added in the Khotan jade after removal of impurities and is ground into ultra-micro powder, grain size is less than 10 μm;
(3) gained powder is subjected to high temperature sintering 10min, temperature is at 600-800 DEG C, and to remove mercury and arsenic therein, cooling is Obtain ultra micro Khotan jade powder.
6. a kind of method preparing Khotan jade anti-aging lotion according to any one of claims 1-4, includes the following steps:
(1) by isopropyl palmitate, caprylic/capric triglyceride, cetylstearyl alcohol, stearic acid, the smooth stearic acid of sorb Ester, polysorbate -60, jojoba seed oil, avocado oil, methyl hydroxybenzoate, Nipasol mixing be heated to 75~80 DEG C it is molten Solution is complete, and A phases are made;
(2) by glycerine, butanediol, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, hyaluronic acid, xanthans, Bis(hydroxymethyl)imidazolidinyl urea, deionized water mixing are heated to 75~80 DEG C of dissolvings completely, and B phases are made;
(3) A is added to B phases, emulsifying homogeneous 3-5min, insulated and stirred 8-10min are to be mixed to be cooled to 40-45 DEG C, in 500- Sedge extract, Japanese cryptotaenia stem and leaf extract, ginseng berry extract, ultra micro Khotan jade powder is added in stirring under 800r/min rotating speeds, Matter 1-2min is cooled to room temperature to get Khotan jade anti-aging lotion.
CN201810511283.4A 2018-05-24 2018-05-24 A kind of Khotan jade anti-aging lotion and preparation method thereof Pending CN108392449A (en)

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CN108888538A (en) * 2018-09-20 2018-11-27 广东山石微量元素研究院(普通合伙) A kind of microelement containing Khotan jade mercury of dispelling restores whitening skin-protection cream

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