CN108309845A - A kind of antibacterial mouthwash of pure plant and preparation method thereof - Google Patents

A kind of antibacterial mouthwash of pure plant and preparation method thereof Download PDF

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Publication number
CN108309845A
CN108309845A CN201810186441.3A CN201810186441A CN108309845A CN 108309845 A CN108309845 A CN 108309845A CN 201810186441 A CN201810186441 A CN 201810186441A CN 108309845 A CN108309845 A CN 108309845A
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CN
China
Prior art keywords
water
pure plant
antibacterial
catechin
antibacterial mouthwash
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810186441.3A
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Chinese (zh)
Inventor
李祖敏
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Zhejiang Yuanmin Science & Technology Co Ltd
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Zhejiang Yuanmin Science & Technology Co Ltd
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Publication date
Application filed by Zhejiang Yuanmin Science & Technology Co Ltd filed Critical Zhejiang Yuanmin Science & Technology Co Ltd
Priority to CN201810186441.3A priority Critical patent/CN108309845A/en
Publication of CN108309845A publication Critical patent/CN108309845A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions
    • A61K2800/5922At least two compounds being classified in the same subclass of A61K8/18

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

A kind of antibacterial mouthwash of pure plant, is made by weight percentage of following components:0.8 1.6% catechin, 0.3 1.0% Herba Swertiae bimaculatae extract, 0.3 1.5% licorice extract, 0.01 0.08% water-soluble menthol, 1.5 10.0% xylitols, 0.1 0.4% sodium benzoate, until 100% purified water.The antibacterial mouthwash of plant of our company's research and development, principle active component is catechin, is that catechin is compounded with Radix Glycyrrhizae, mint extract, xylitol, pure water, produces and be made in the environment of aseptic.Product is without any side effects, non-stimulated to oral cavity, can effectively inhibit bacterium, protects oral cavity cleaning and heath.And have prevention decayed tooth, reduce plaque and slow down periodontosis effect and deodouring effect, to treating and preventing saprodontia from having good result.

Description

A kind of antibacterial mouthwash of pure plant and preparation method thereof
Technical field
The present invention relates to dental care products fields, and in particular to a kind of antibacterial mouthwash of pure plant and preparation method thereof.
Background technology
In recent years, the concern with people to health with the development of economy, national oral care consciousness are stepped up, are consumed Pattern persistently upgrades, and has driven the rapid growth of mouthrinse product.There is principal ingredients contained by current market sales of mouthwash Sodium fluoride, thymol, triclosan, chlorhexidine gluconate, gaultherolin etc., these chemical agents, which no doubt meet safety, to be wanted It asks, but long-time service can still generate mucous membrane of mouth certain stimulation, once being eaten by mistake by user, may be produced to digestive system Raw injury.
People are not very willing to use for using chemical agent to compound the worry of mouthwash simultaneously.And plant is antibacterial gargles Saliva main component is to extract catechin from tealeaves, is pure natural substance, has effects that sterilization, anti-caries, antioxygen power is strong, can Teeth space, dental cavity are penetrated into, bacterium is effectively inhibited, oral cavity cleaning and heath is protected, is welcome by more and more consumers, development prospect Wide, potential market is very big.
Invention content
To solve the above-mentioned problems, the present invention provides antibacterial mouthwashes of a kind of pure plant and preparation method thereof.
The technical solution adopted in the present invention is:
A kind of antibacterial mouthwash of pure plant, is made by weight percentage of following components:0.5-1.8% flavanols derives Object, 0.2-1.0% Herba Swertiae bimaculatae extracts, 0.3-1.5% licorice extracts, the water-soluble menthols of 0.01-0.12%, 1.5-10.0% Xylitol, 0.1-0.4% sodium benzoates, until 100% purified water.
Preferably, the flavane 01 derivatives are catechin.
Preferably, the antibacterial mouthwash of a kind of pure plant is made by weight percentage of following components:0.8-1.6% catechu Element, 0.3-1.0% Herba Swertiae bimaculatae extracts, 0.3-1.5% licorice extracts, the water-soluble menthols of 0.01-0.08%, 1.5-10.0% Xylitol, 0.1-0.4% sodium benzoates, until 100% purified water.
The preparation method of above-mentioned mouthwash, includes the following steps:
Xylitol is added in dissolution kettle step 1., addition purified water, stirring and dissolving under room temperature;
Herba Swertiae bimaculatae extract is added in dissolution kettle step 2., opens homogeneous, stirring is to being completely dissolved;
Remaining whole materials are added in step 3., stir 30min;
Step 4. stands 15min, filters blowing, is sent into filling workshop section.
The main active principle of this item purpose is catechin, and catechin is that one kind that comparision contents are abundant in tealeaves is functional living Property ingredient, it is 12%~24% to have extensive health care and pharmacological effect, mass fraction (in terms of cured leaf) in tealeaves, is had Prevent decayed tooth effect and removes halitosis effect.Because containing fluorine in tealeaves, it is possible to make tooth that there is the erosion of acid stronger Resistance;Catechin can remove the stink of methyl mercaptan, it is possible to remove the halitosis of smoker.Catechin is that flavanols derives Object can kill the lactic acid bacteria present in slot and other caries bacterias, have the function of inhibiting glucose polymerisation enzymatic activity, In this way germ cannot on tooth implantation, effectively interrupted make saprodontia formed process.Remain on the protein food in slot Object is the matrix of putrefactivebacteria proliferation, and catechin can kill such bacterium, it will be apparent that reduces plaque and slows down periodontosis.
This project selects Herba Swertiae bimaculatae extract, and licorice extract, water-soluble menthol, xylitol, sodium benzoate is dispensing. River deer bean sprout has effects that prevent and improve aphtha and toothache;Radix Glycyrrhizae has anti-inflammatory, anti-allergic effects, can protect inflammation throat and Tunica mucosa tracheae;Peppermint contains menthol, the substance can fresh breath and have a variety of pharmacological properties, abdominal pain spasm can be alleviated, also had Antisepsis and sterilization, diuresis, resolving sputum, stomach invigorating and aid digestion and other effects;Xylitol cool taste, anti-caries characteristic are in all sweet tastes Effect is best in agent, it is not produced cariogenic bacterial fermentation and utilized in oral cavity, can inhibit the generation of streptococcus growth and acid.
Project is designed by optimization of C/C composites, obtains its optimum proportioning, make the pharmacological effect of various dispensings obtain maximum synergy, Promote.Optimize technique design simultaneously, by the pretreatment to material, using included suction cellular type high temperature resistant reaction kettle and " 100,000 The outfit of grade " purification sterile workshop uses, and realizes " cooking-pot type " production technology, saves intermediate link, prevented by manual operation The quality fluctuation brought, entire production process realize that automation accurately controls, improve product quality.
The antibacterial mouthwash of plant of our company's research and development, principle active component is catechin, is that catechin is carried with Radix Glycyrrhizae, peppermint Object, xylitol, pure water compounding are taken, produces and is made in the environment of aseptic.Product is without any side effects, stingless to oral cavity Swash, can effectively inhibit bacterium, protects oral cavity cleaning and heath.And there is prevention decayed tooth, reduces plaque and slow down periodontosis work With and deodouring effect, to treating and preventing saprodontia from having good result.
Specific implementation mode
Embodiment 1:A kind of antibacterial mouthwash of pure plant, is made by weight percentage of following components:0.8% catechin, 0.3% Herba Swertiae bimaculatae extract, 0.3% licorice extract, 0.01% water-soluble menthol, 1.5% xylitol, 0.1% sodium benzoate, To 100% purified water.
Embodiment 2:A kind of antibacterial mouthwash of pure plant, is made by weight percentage of following components:1.6% catechin, 1.0% Herba Swertiae bimaculatae extract, 1.5% licorice extract, 0.08% water-soluble menthol, 10.0% xylitol, 0.4% benzoic acid Sodium, until 100% purified water.
Embodiment 3:A kind of antibacterial mouthwash of pure plant, is made by weight percentage of following components:1.2% catechin, 0.5% Herba Swertiae bimaculatae extract, 0.7% licorice extract, 0.05% water-soluble menthol, 8% xylitol, 0.2% sodium benzoate, until 100% purified water.
Embodiment 4:A kind of antibacterial mouthwash of pure plant, is made by weight percentage of following components:0.9% catechin, 0.6% Herba Swertiae bimaculatae extract, 0.38% licorice extract, 0.06% water-soluble menthol, 7.2% xylitol, 0.3% benzoic acid Sodium, until 100% purified water.
Obviously, the above embodiment of the present invention is intended to be merely illustrative of the present example, and not to the present invention Embodiment restriction.For those of ordinary skill in the art, it can also make on the basis of the above description Other various forms of variations or variation.There is no need and unable to give poor example to all embodiments.And these belong to this The connotation changes and variations that derived from of invention still fall within protection scope of the present invention.

Claims (4)

1. a kind of antibacterial mouthwash of pure plant, it is characterised in that:It is made by weight percentage of following components:0.5-1.8% is yellow Alkanol derivatives, 0.2-1.0% Herba Swertiae bimaculatae extracts, 0.3-1.5% licorice extracts, the water-soluble menthols of 0.01-0.12%, 1.5-10.0% xylitols, 0.1-0.4% sodium benzoates, until 100% purified water.
2. the antibacterial mouthwash of a kind of pure plant according to claim 1, it is characterised in that:The flavane 01 derivatives are youngster Theine.
3. the antibacterial mouthwash of a kind of pure plant according to claim 2, it is characterised in that:A kind of pure plant is antibacterial to gargle Water is made by weight percentage of following components:0.8-1.6% catechins, 0.3-1.0% Herba Swertiae bimaculatae extracts, 0.3-1.5% Licorice extract, the water-soluble menthols of 0.01-0.08%, 1.5-10.0% xylitols, 0.1-0.4% sodium benzoates, until 100% is pure Change water.
4. according to the preparation method of the antibacterial mouthwash of pure plant described in claim 1-3 any one, include the following steps:
Xylitol is added in dissolution kettle step 1., addition purified water, stirring and dissolving under room temperature;
Herba Swertiae bimaculatae extract is added in dissolution kettle step 2., opens homogeneous, stirring is to being completely dissolved;
Remaining whole materials are added in step 3., stir 30min;
Step 4. stands 15min, filters blowing, is sent into filling workshop section.
CN201810186441.3A 2018-03-07 2018-03-07 A kind of antibacterial mouthwash of pure plant and preparation method thereof Pending CN108309845A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114469794A (en) * 2020-10-28 2022-05-13 南京中科游子生物技术研究院有限公司 Green tea active substance mouthwash composition and preparation method thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106176546A (en) * 2016-08-26 2016-12-07 湖北立天生物工程有限公司 Based on the cleaning of the chitosan derivatives degree of depth, bacteriostatic tooth protective collutory and preparation method thereof
CN107184476A (en) * 2017-06-16 2017-09-22 河北康正药业有限公司 A kind of antibacterial mouthwash and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106176546A (en) * 2016-08-26 2016-12-07 湖北立天生物工程有限公司 Based on the cleaning of the chitosan derivatives degree of depth, bacteriostatic tooth protective collutory and preparation method thereof
CN107184476A (en) * 2017-06-16 2017-09-22 河北康正药业有限公司 A kind of antibacterial mouthwash and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
佚名: "《http://cosdna.com/chs/cosmetic_838866552.html》", 18 November 2011 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114469794A (en) * 2020-10-28 2022-05-13 南京中科游子生物技术研究院有限公司 Green tea active substance mouthwash composition and preparation method thereof

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Application publication date: 20180724