CN107242993A - A kind of spearmint ferment mouthwash and preparation method thereof - Google Patents
A kind of spearmint ferment mouthwash and preparation method thereof Download PDFInfo
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- CN107242993A CN107242993A CN201710487173.4A CN201710487173A CN107242993A CN 107242993 A CN107242993 A CN 107242993A CN 201710487173 A CN201710487173 A CN 201710487173A CN 107242993 A CN107242993 A CN 107242993A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a kind of spearmint ferment mouthwash and preparation method thereof.The spearmint ferment mouthwash includes according to mass fraction：3 parts of spearmint ferment, 8 parts of tea ferment, 2 parts of bletilla striata extract, 0.3 part of thyme extract, 5 parts of licorice extract, 2 parts of catechin, 0.5 part of pH adjusting agent, 8 parts of cleaning agent, 5 parts of sweetener, 0.5 part of flavouring agent, 2 parts of colouring agent, 2 parts of solubilizer, purified water supplies 100 parts.The spearmint ferment of the present invention is gargled, by the way of plant enzyme and natural plant active component are used in combination, common to improve oral cavity gas, intraoral fresh air is set to extend, not only there is cleaning, anti-inflammatory, hypo-allergenic effect, and natural no stimulation, suitable various people use.
Description
Technical field
The present invention relates to medicines and health protection technical field, and in particular to a kind of spearmint ferment mouthwash and preparation method thereof.
Background technology
With the development of society, people be required for carrying out daily it is such as social, negotiate, report the work, entertaining, affection exchange
Various communications, therefore dental care product, as cleaning indispensable in people's daily life and health treatment, it is led
It is used to keep oral cavity and cleaning of teeth, promotes breath freshening, nurse gum, safeguard oral cavity good environment etc..And mouthwash is made
For a kind of common oral cavity cleaning and nursing product, because having the characteristics of easy to use, oral cavity cleaning function is strong, a kind of mouth is increasingly becoming
The fashion custom of chamber cleaning.
In recent years, the continuous enhancing of consumer healthcare's consciousness, higher requirement is proposed to mouthwash, is also increased except cleaning the teeth
Impression requirement in some sense of taste, and there is also a need for having nursing health effect to oral cavity.But in order to reach antibacterial and anti-inflammatory mesh
, the mainly contain triclosan or metronidazole, Tinidazole, hydrogen peroxide, iodine solution, alcohol etc. of most mouthwash have thorn to human body
Swash property or the chemical substance of injury.For example：A kind of Publication No. CN104644505A breath freshening mouthwash of Chinese patent, contains
Have Cortex Periplocae Radicis extract 0.02~0.5%, Flos Caryophylli extract 0.5~2%, Artemisinin 0.5~2%, sorbierite 18~
21%th, food grade ethanol 10~12%, nipalgin mixed ester sodium 0.1~0.2%, rilanit special 0.7~0.9%, deionization
Water surplus, it is in order to reach good fungistatic effect, and ethanol content has reached 10~12%, and excitant is strong, and influence is used for a long time
Physiology of oral cavity environment.
Active components of plants has pure natural, green safety etc., the incomparable advantage of Western medicine, therefore the present invention proposes one kind
Spearmint ferment mouthwash based on pure plant active component, supplemented by Western medicine, without excitant, harmful chemical component, energy
Effectively dispel oral cavity swill, bacterial plaque, calculus dentalis dirt etc., long-acting fresh breath.
The content of the invention
The purpose of the present invention is to solve the shortcomings of the prior art there is provided a kind of green, safe, non-stimulated one kind for part
Spearmint ferment mouthwash and preparation method thereof, can effectively dispel oral peculiar smell, suppress bacteria breed.
To achieve the above object, the invention provides a kind of spearmint ferment mouthwash.Specifically, the spearmint ferment
Mouthwash includes according to mass fraction：3 parts of spearmint ferment, 8 parts of tea ferment, 2 parts of bletilla striata extract, thyme extract 0.3
Part, 5 parts of licorice extract, 2 parts of catechin, 0.5 part of pH adjusting agent, 8 parts of cleaning agent, 5 parts of sweetener, 0.5 part of flavouring agent, coloring
2 parts of agent, 2 parts of solubilizer, purified water supplies 100 parts.
Preferably, the tea ferment is that Pu'er tea, black tea or green tea fermentation are made.
Preferably, the pH adjusting agent includes citric acid.
Preferably, the cleaning agent includes sorbierite.
Preferably, the sweetener includes xylitol.
Preferably, the flavouring agent includes natural peppermint.
Preferably, the colouring agent includes Cl42090.
Preferably, the solubilizer includes efficient solubilizing agents 115C.
Second aspect of the present invention provides a kind of preparation method of spearmint ferment mouthwash.Specifically, methods described bag
Include following steps：
Step 1: being weighed respectively according to mass fraction in 3 parts of spearmint ferment, 8 parts of tea ferment, 2 parts of bletilla striata extract, hundred
Fragrant 0.3 part of extract, 5 parts of licorice extract, 2 parts of catechin, 0.5 part of pH adjusting agent, 8 parts of cleaning agent, 5 parts of sweetener, fragrance
0.5 part of agent, 2 parts of colouring agent, 2 parts of solubilizer；
Step 2: to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin,
Added in pH adjusting agent, cleaning agent, sweetener, colouring agent under solubilizer, normal temperature plus purified water is stirred to whole dissolvings, be made and match somebody with somebody
Solution processed；
Step 3: adding purified water to gross mass number into the preparation solution reaches 100 parts, stir, stand
4h, adds flavouring agent precipitation 5~9 days, and precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, encapsulation produces spearmint ferment mouthwash.
The inventive method has the following advantages that：
1st, spearmint ferment mouthwash of the present invention, passes through plant enzyme spearmint ferment, tea ferment and natural plant active
Composition bletilla striata extract, thyme extract, licorice extract are combined, without Tinidazole, hydrogen peroxide, iodine solution, alcohol etc.
Irritant compound, not only in good taste, non-stimulated, moreover it is possible to effectively to dispel oral cavity swill, bacterial plaque, calculus dentalis dirt is prevented
Only hemodia, long-acting fresh breath.
2nd, spearmint ferment mouthwash of the present invention, using plurality of active ingredients reasonable compatibility, makes to cooperate with work between its each component
With so that mouthwash taste of the invention is new and graceful, and property is stable, in addition, the preparation method of the present invention is simple and easy to apply, preparation condition
Gently, suitable for a wide range of popularization and application.
Embodiment
Following examples are used to illustrate the present invention, but are not limited to the scope of the present invention.
Embodiment 1
The preparation method of the present embodiment spearmint ferment mouthwash, is carried out according to the following steps：
Step 1: weighing spearmint ferment 15g, Pu'er tea ferment 40g, bletilla striata extract respectively according to mass fraction
10g, thyme extract 1.5g, licorice extract 25g, catechin 10g, citric acid 2.5g, sorbierite 40g, xylitol 25g,
Natural peppermint 2.5g, Cl42090 10g, efficient solubilizing agents 115C 10g；
Step 2: to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin,
Added in citric acid, sorbierite, xylitol, Cl42090 under efficient solubilizing agents 115C, normal temperature plus purified water is stirred to all molten
Solution, is made and prepares solution；
Step 3: adding purified water to gross mass into the preparation solution reaches 500g, stir, stand 4h, plus
Enter natural peppermint precipitation 7 days, precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, according to QB/T2945-2012 oral cavity cleaning and nursing liquid mark into
Row detection, it is qualified after be packaged, adhesive label and security code (date of manufacture, lot number, term of validity etc.) produce spearmint ferment
Mouthwash.
Embodiment 2
The preparation method of the present embodiment spearmint ferment mouthwash, is carried out according to the following steps：
Step 1: weighing spearmint ferment 45g, black tea tea ferment 120g, bletilla striata extract respectively according to mass fraction
30g, thyme extract 4.5g, licorice extract 75g, catechin 30g, citric acid 7.5g, sorbierite 120g, xylitol 75g,
Natural peppermint 7.5g, Cl42090 30g, efficient solubilizing agents 115C 30g；
Step 2: to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin,
Added in citric acid, sorbierite, xylitol, Cl42090 under efficient solubilizing agents 115C, normal temperature plus purified water is stirred to all molten
Solution, is made and prepares solution；
Step 3: adding purified water to gross mass into the preparation solution reaches 1500g, stir, stand 4h, plus
Enter natural peppermint precipitation 5 days, precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, according to QB/T2945-2012 oral cavity cleaning and nursing liquid mark into
Row detection, it is qualified after be packaged, adhesive label and security code (date of manufacture, lot number, term of validity etc.) produce spearmint ferment
Mouthwash.
Embodiment 3
The preparation method of the present embodiment spearmint ferment mouthwash, is carried out according to the following steps：
Step 1: weighed respectively according to mass fraction spearmint ferment 18g, green tea tea ferment 48g, bletilla striata extract 12g,
Thyme extract 1.8g, licorice extract 30g, catechin 12g, citric acid 3g, sorbierite 48g, xylitol 30g, natural thin
Lotus 3g, Cl42090 12g, efficient solubilizing agents 115C 12g；
Step 2: to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin,
Added in citric acid, sorbierite, xylitol, Cl42090 under efficient solubilizing agents 115C, normal temperature plus purified water is stirred to all molten
Solution, is made and prepares solution；
Step 3: adding purified water to gross mass into the preparation solution reaches 600g, stir, stand 4h, plus
Enter natural peppermint precipitation 8 days, precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, according to QB/T2945-2012 oral cavity cleaning and nursing liquid mark into
Row detection, it is qualified after be packaged, adhesive label and security code (date of manufacture, lot number, term of validity etc.) produce spearmint ferment
Mouthwash.
Embodiment 4
The preparation method of the present embodiment spearmint ferment mouthwash, is carried out according to the following steps：
Step 1: weighing spearmint ferment 30g, Pu'er tea ferment 80g, bletilla striata extract respectively according to mass fraction
It is 20g, thyme extract 3g, licorice extract 50g, catechin 20g, citric acid 5g, sorbierite 80g, xylitol 50g, natural
Peppermint 5g, Cl42090 20g, efficient solubilizing agents 115C 20g；
Step 2: to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin,
Added in citric acid, sorbierite, xylitol, Cl42090 under efficient solubilizing agents 115C, normal temperature plus purified water is stirred to all molten
Solution, is made and prepares solution；
Step 3: adding purified water to gross mass into the preparation solution reaches 1000g, stir, stand 4h, plus
Enter natural peppermint precipitation 9 days, precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, according to QB/T2945-2012 oral cavity cleaning and nursing liquid mark into
Row detection, it is qualified after be packaged, adhesive label and security code (date of manufacture, lot number, term of validity etc.) produce spearmint ferment
Mouthwash.
Embodiment 5
The preparation method of the present embodiment spearmint ferment mouthwash, is carried out according to the following steps：
Step 1: weighed respectively according to mass fraction spearmint ferment 24g, green tea tea ferment 64g, bletilla striata extract 16g,
Thyme extract 2.4g, licorice extract 40g, catechin 16g, citric acid 4g, sorbierite 64g, xylitol 40g, natural thin
Lotus 4g, Cl42090 16g, efficient solubilizing agents 115C 16g；
Step 2: to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin,
Added in citric acid, sorbierite, xylitol, Cl42090 under efficient solubilizing agents 115C, normal temperature plus purified water is stirred to all molten
Solution, is made and prepares solution；
Step 3: adding purified water to gross mass into the preparation solution reaches 800g, stir, stand 4h, plus
Enter natural peppermint precipitation 6 days, precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, according to QB/T2945-2012 oral cavity cleaning and nursing liquid mark into
Row detection, it is qualified after be packaged, adhesive label and security code (date of manufacture, lot number, term of validity etc.) produce spearmint ferment
Mouthwash.
Embodiment 6
The preparation method of the present embodiment spearmint ferment mouthwash, is carried out according to the following steps：
Step 1: weighing spearmint ferment 36g, Pu'er tea ferment 96g, bletilla striata extract respectively according to mass fraction
24g, thyme extract 3.6g, licorice extract 60g, catechin 24g, citric acid 6g, sorbierite 96g, xylitol 60g, day
Right peppermint 6g, Cl42090 24g, efficient solubilizing agents 115C 24g；
Step 2: to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin,
Added in citric acid, sorbierite, xylitol, Cl42090 under efficient solubilizing agents 115C, normal temperature plus purified water is stirred to all molten
Solution, is made and prepares solution；
Step 3: adding purified water to gross mass into the preparation solution reaches 1200g, stir, stand 4h, plus
Enter natural peppermint precipitation 7 days, precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, according to QB/T2945-2012 oral cavity cleaning and nursing liquid mark into
Row detection, it is qualified after be packaged, adhesive label and security code (date of manufacture, lot number, term of validity etc.) produce spearmint ferment
Mouthwash.
Wherein, spearmint ferment is the spearmint ferment powder that Lanzhou water Lai Si bio tech ltd is produced；Tea ferment
The tea ferment that element produces for Lanzhou water Lai Si bio tech ltd；Bletilla striata extract is that Nanjing Dao Sifu biotechnologies have
Limit company produces；Thyme extract produces for Nanjing Dao Sifu bio tech ltd；Licorice extract is Xi'an Chang Yue
Bio tech ltd is produced；Cl42090 is blue 1 color lake pigment；Efficient solubilizing agents 115C is that Shenzhen's Ou Fulin technologies have
Limit company produces.
Application method：Once in the morning and once at night, gargled every time with 15~20mL spearmint ferment mouthwashes all over oral cavity, teeth space and tooth
Gum, then faces upward head, spues, can not swallow after gargling 30 seconds.Taking spearmint ferment mouthwash please don't be diluted with water.
The course for the treatment of：One bottle (500mL) course for the treatment of, it is proposed that use two to three courses for the treatment of.
The present invention chooses porphyromonas gingivalis, Prevotella, actinomyces viscosus, Escherichia coli, golden yellow Portugal
This five kinds of bacterium of grape coccus and the progress antibacterial experiment of reference GB 15979-2002 appendix Cs 3, bacteriostasis rate=(control group survival bacterium number-
Experimental group survival bacterium number)/control group survival bacterium number.
Table 1 is the antibacterial test result of spearmint ferment mouthwash prepared by embodiment 1~6
From table 1 it follows that spearmint ferment mouthwash prepared by the embodiment of the present application 1~6 is to porphyromonas unit cell
Bacterium, Prevotella, actinomyces viscosus, Escherichia coli, staphylococcus aureus have stronger inhibition, especially right
Golden yellow grape inhibition is most strong, can effectively suppress the growth of oral cavity bacterium, long-acting fresh breath.
Although above with general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements, belong to the scope of protection of present invention without departing from theon the basis of the spirit of the present invention.
Claims (9)
1. a kind of spearmint ferment mouthwash, it is characterised in that：The spearmint ferment mouthwash includes according to mass fraction：Stay
Blue 3 parts of ferment of perfume, 8 parts of tea ferment, 2 parts of bletilla striata extract, 0.3 part of thyme extract, 5 parts of licorice extract, catechin 2
Part, 0.5 part of pH adjusting agent, 8 parts of cleaning agent, 5 parts of sweetener, 0.5 part of flavouring agent, 2 parts of colouring agent, 2 parts of solubilizer, purified water are mended
100 parts of foot.
2. spearmint ferment mouthwash according to claim 1, it is characterised in that：The tea ferment is Pu'er tea, black tea
Or green tea fermentation is made.
3. spearmint ferment mouthwash according to claim 1, it is characterised in that：The pH adjusting agent includes citric acid.
4. spearmint ferment mouthwash according to claim 1, it is characterised in that：The cleaning agent includes sorbierite.
5. spearmint ferment mouthwash according to claim 1, it is characterised in that：The sweetener includes xylitol.
6. spearmint ferment mouthwash according to claim 1, it is characterised in that：The flavouring agent includes natural peppermint.
7. spearmint ferment mouthwash according to claim 1, it is characterised in that：The colouring agent includes Cl42090.
8. spearmint ferment mouthwash according to claim 1, it is characterised in that：The solubilizer includes efficient solubilizing agents
115C。
9. a kind of preparation method of the spearmint ferment mouthwash described in claim 1, it is characterised in that：The preparation method bag
Include：
Carried Step 1: weighing 3 parts of spearmint ferment, 8 parts of tea ferment, 2 parts of bletilla striata extract, thyme respectively according to mass fraction
Take 0.3 part of thing, 5 parts of licorice extract, 2 parts of catechin, 0.5 part of pH adjusting agent, 8 parts of cleaning agent, 5 parts of sweetener, flavouring agent 0.5
Part, 2 parts of colouring agent, 2 parts of solubilizer；
Step 2: being adjusted to spearmint ferment, tea ferment, bletilla striata extract, thyme extract, licorice extract, catechin, pH
Added in section agent, cleaning agent, sweetener, colouring agent under solubilizer, normal temperature plus purified water is stirred to whole dissolvings, be made and prepare molten
Liquid；
Step 3: adding purified water to gross mass number into the preparation solution reaches 100 parts, stir, stand 4h, plus
Enter flavouring agent precipitation 5~9 days, precipitation solution is made；
Step 4: precipitation solution is crossed into 800 mesh sieves, sterilize, encapsulation produces spearmint ferment mouthwash.
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| CN115590900A (en) * | 2022-10-10 | 2023-01-13 | 湖南循力源口腔疾病研究院有限公司（Cn） | Application of traditional Chinese medicine volatile oil in substances for preventing and treating halitosis |
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| CN115590900A (en) * | 2022-10-10 | 2023-01-13 | 湖南循力源口腔疾病研究院有限公司（Cn） | Application of traditional Chinese medicine volatile oil in substances for preventing and treating halitosis |
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