CN102764219A - Sterilizing mouthwash for oral cavities - Google Patents

Sterilizing mouthwash for oral cavities Download PDF

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Publication number
CN102764219A
CN102764219A CN2012102796346A CN201210279634A CN102764219A CN 102764219 A CN102764219 A CN 102764219A CN 2012102796346 A CN2012102796346 A CN 2012102796346A CN 201210279634 A CN201210279634 A CN 201210279634A CN 102764219 A CN102764219 A CN 102764219A
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CN
China
Prior art keywords
mouthwash
sterilizing
oral
collutory
oral cavities
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN2012102796346A
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Chinese (zh)
Inventor
王金强
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SHANDONG KING FIRST DISINFECTION TECHNOLOGY Co Ltd
Original Assignee
SHANDONG KING FIRST DISINFECTION TECHNOLOGY Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SHANDONG KING FIRST DISINFECTION TECHNOLOGY Co Ltd filed Critical SHANDONG KING FIRST DISINFECTION TECHNOLOGY Co Ltd
Priority to CN2012102796346A priority Critical patent/CN102764219A/en
Publication of CN102764219A publication Critical patent/CN102764219A/en
Pending legal-status Critical Current

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  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention discloses a sterilizing mouthwash for oral cavities. The sterilizing mouthwash is made up of the following components: 0.02-0.2% of chlorhexidine acetate, 0.05-0.1% of chitosan, 2-10% of xylitol, 0.001-0.01% of peppermint oil and the balance of purified water. The mouthwash is capable of drastically killing off the pathogenic bacteria which cause various oral diseases such as anaerobic bacteria, candida albicans, staphyloccocus aureus and streptococcus pyogens, and controlling the pathogenic bacteria to avoid dust; and the mouthwash does not contain alcohol, so that no side effect is caused in the oral cavities and the human bodies.

Description

A kind of sterilizing oral collutory
Technical field
The present invention relates to a kind of sterilizing oral collutory.
Background technology
In recent years; The sickness rate of oral pathology is high; Along with the raising of living standards of the people and health perception, the control of oral disease and the protection of tooth are more and more important, and the MC means that Traditional use toothpaste is brushed teeth exist uses inconvenience; Clear up untimely, not thoroughly, tooth had drawback such as wearing and tearing, be difficult to satisfy people's oral cavity cleaning requirement.
Collutory is as a kind of emerging oral cavity cleaning and nursing product; Generally be contained in the portable Packaging Bottle; Can use at any time; Thoroughly overcome drawbacks such as MC is untimely, toothpaste uses inconvenience, cleaning is not thorough, effects such as its cleaning oral cavity, caries prevention and periodontitis obviously are better than traditional toothpaste, and then very popular in recent years.But according to Britain " Daily Mail ", the research evidence shows that collutory on the market mostly contains alcoholic content; Alcohol content in some collutory is up to 26%; Professor Luo Binximo of the restorative dentistry of University of Newcastle representes that ethanol itself can destroy and keep the moistening private film in oral cavity, makes xerostomia; And then cause halitosis, also can make the oral cavity produce uncomfortable prickling sensation.Treatment the Chairman of the Board of Australian dentist association in 2009, the professor Michael of University of Melbourne Alexander McCulloch; To using the people of collutory to investigate 3210 every days; He " is publishing an article on the Australian dentistry journal and is pointing out; He has abundant proof to prove, the protective layer that the ethanol in the collutory can make carcinogen such as nicotine permeate the oral cavity more easily raises risk of cancer.
Summary of the invention
To containing alcoholic content in the existing collutory product, the problem of side effect is brought in oral cavity and human body, the object of the present invention is to provide a kind of cleaning effect good, avoid bringing the sterilizing oral collutory of side effect.
For achieving the above object, a kind of sterilizing oral collutory provided by the invention, it contains following component at least and mass percent is: chlorhexidine acetate 0.02%-0.2%; Chitosan 0.05%-0.1%; Xylitol 2%-10%, Oleum menthae 0.001%-0.01%, surplus is a purified water.
The present invention is not confined to said components, under the condition that satisfies the said components proportioning, also can add other auxiliary elements.
The present invention has following beneficial effect: it can thoroughly penetrate a mouthful bacterial plaque nucleus; Effective ingredient is directly acted on its kernel; Kill pathogenic bacterium such as the anaerobe that causes various oral diseases, Candida albicans, staphylococcus glucose coccus, pyococcus and control it and grow; Reduce nosocomial infection and postoperation of oral cavity and infect antibacterial tooth protection, counteract oral malodour.For staphylococcus aureus and Candida albicans are respectively acted on two minutes, average bacteriostasis rate is 100% through bacteriostatic test gained result; It is soft, can not bring side effect to the oral cavity and the person.
The specific embodiment
Embodiment one
Use the high-precision electronic balance to take by weighing: chlorhexidine acetate 0.2g, chitosan 0.5g, xylitol 20g, Oleum menthae 0.01g, purified water 979.29g; Successively chlorhexidine acetate, chitosan, xylitol, Oleum menthae are put into purified water respectively and fully dissolve, obtain this sterilizing oral collutory at last, this collutory is a colourless transparent liquid, mint flavored, clean taste.For staphylococcus aureus and Candida albicans are respectively acted on two minutes, average bacteriostasis rate is 100% through bacteriostatic test gained result.
Embodiment two
Use the high-precision electronic balance to take by weighing: chlorhexidine acetate 2g, chitosan 1g, xylitol 100g, Oleum menthae 0.1g, purified water 896.9g; Successively chlorhexidine acetate, chitosan, xylitol, Oleum menthae are put into purified water respectively and fully dissolve, obtain this sterilizing oral collutory at last.This collutory is a colourless transparent liquid, mint flavored, clean taste.For staphylococcus aureus and Candida albicans are respectively acted on two minutes, average bacteriostasis rate is 100% through bacteriostatic test gained result.
Embodiment three
Use the high-precision electronic balance to take by weighing: chlorhexidine acetate 1g, chitosan 0.75g, xylitol 60g, Oleum menthae 0.05g, purified water 938.2g; Successively chlorhexidine acetate, chitosan, xylitol, Oleum menthae are put into purified water respectively and fully dissolve, obtain this sterilizing oral collutory at last.This collutory is a colourless transparent liquid, mint flavored, clean taste.For staphylococcus aureus and Candida albicans are respectively acted on two minutes, average bacteriostasis rate is 100% through bacteriostatic test gained result.

Claims (1)

1. sterilizing oral collutory, it is characterized in that: it contains following component at least and mass percent is: chlorhexidine acetate 0.02%-0.2% chitosan 0.05%-0.1%, xylitol 2%-10%, Oleum menthae 0.001%-0.01%, surplus is a purified water.
CN2012102796346A 2012-07-27 2012-07-27 Sterilizing mouthwash for oral cavities Pending CN102764219A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN2012102796346A CN102764219A (en) 2012-07-27 2012-07-27 Sterilizing mouthwash for oral cavities

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN2012102796346A CN102764219A (en) 2012-07-27 2012-07-27 Sterilizing mouthwash for oral cavities

Publications (1)

Publication Number Publication Date
CN102764219A true CN102764219A (en) 2012-11-07

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Family Applications (1)

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CN2012102796346A Pending CN102764219A (en) 2012-07-27 2012-07-27 Sterilizing mouthwash for oral cavities

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CN (1) CN102764219A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103932914A (en) * 2013-09-03 2014-07-23 浙江康德药业集团有限公司 Chitosan mouthwash and preparation method thereof
CN104606085A (en) * 2013-11-22 2015-05-13 中国人民解放军第三军医大学 Novel efficient antimicrobial chlorhexidine acetate nanoemulsion gargle and preparation method thereof
CN104644478A (en) * 2013-11-19 2015-05-27 山东瑞泰奇洗涤消毒科技有限公司 Sterilizing type gargle with nursing repair effect
CN104739685A (en) * 2013-12-26 2015-07-01 上海利康消毒高科技有限公司 Gargle containing chlorhexidine gluconate and preparation method thereof
CN105919829A (en) * 2016-06-29 2016-09-07 贵州扬生医用器材有限公司 Mouthwash and preparation method thereof
CN112402320A (en) * 2020-11-30 2021-02-26 深圳南粤药业有限公司 Gargle for preventing and treating radioactive xerostomia and preparation method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1304715A (en) * 2000-11-25 2001-07-25 余照恩 Process for preparing gargle

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1304715A (en) * 2000-11-25 2001-07-25 余照恩 Process for preparing gargle

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
刘华钢: "《中成药学》", 30 June 1998, 人民卫生出版社 *
张爱知,等: "《实用药物手册》", 31 May 1994, 上海科学技术出版社 *
李家仁,等: "洗必泰制剂及其临床应用", 《中级医刊》 *
许树梧: "《临床用药精要》", 31 March 2001, 人民卫生出版社 *
顾觉奋: "《分离纯化工艺原理》", 31 August 2002, 中国医药科技出版社 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103932914A (en) * 2013-09-03 2014-07-23 浙江康德药业集团有限公司 Chitosan mouthwash and preparation method thereof
CN103932914B (en) * 2013-09-03 2016-06-08 浙江康德药业集团股份有限公司 Chitosan collutory and its preparation method
CN104644478A (en) * 2013-11-19 2015-05-27 山东瑞泰奇洗涤消毒科技有限公司 Sterilizing type gargle with nursing repair effect
CN104606085A (en) * 2013-11-22 2015-05-13 中国人民解放军第三军医大学 Novel efficient antimicrobial chlorhexidine acetate nanoemulsion gargle and preparation method thereof
CN104739685A (en) * 2013-12-26 2015-07-01 上海利康消毒高科技有限公司 Gargle containing chlorhexidine gluconate and preparation method thereof
CN105919829A (en) * 2016-06-29 2016-09-07 贵州扬生医用器材有限公司 Mouthwash and preparation method thereof
CN105919829B (en) * 2016-06-29 2018-11-09 贵州扬生医用器材有限公司 A kind of mouthwash and preparation method thereof
CN112402320A (en) * 2020-11-30 2021-02-26 深圳南粤药业有限公司 Gargle for preventing and treating radioactive xerostomia and preparation method thereof
CN112402320B (en) * 2020-11-30 2021-06-29 深圳南粤药业有限公司 Gargle for preventing and treating radioactive xerostomia and preparation method thereof

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Application publication date: 20121107