CN106109366A - A kind of collutory and preparation method thereof - Google Patents

A kind of collutory and preparation method thereof Download PDF

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Publication number
CN106109366A
CN106109366A CN201610783557.6A CN201610783557A CN106109366A CN 106109366 A CN106109366 A CN 106109366A CN 201610783557 A CN201610783557 A CN 201610783557A CN 106109366 A CN106109366 A CN 106109366A
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CN
China
Prior art keywords
chinese medicine
collutory
medicine extract
parts
deionized water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201610783557.6A
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Chinese (zh)
Inventor
王卫
周平乐
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Nanjing Jusha Display Technology Co Ltd
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Nanjing Jusha Display Technology Co Ltd
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Publication date
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Priority to CN201610783557.6A priority Critical patent/CN106109366A/en
Publication of CN106109366A publication Critical patent/CN106109366A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/20Halogens; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/22Peroxides; Oxygen; Ozone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84Products or compounds obtained by lyophilisation, freeze-drying

Abstract

The invention discloses one and effectively remove removing abnormal flavor in oral cavity, collutory of long-acting holding breath freshening and preparation method thereof.In terms of mass fraction, this collutory mainly includes antibacterial 0.1%~5%, Chinese medicine extract 0.1%~5%, glycerol 2%~10%, and surplus is deionized water.Wherein Chinese medicine extract includes Flos Lonicerae 3~5 parts, mentha leave 2~4 parts, Radix Glycyrrhizae 3~5 parts, Flos Chrysanthemi 4~9 parts, Flos Caryophylli 3~9 parts.The present invention Oxidation by antibacterial, the volatile sulfur compounds in removable oral cavity, make tasteless product and suppress implication.Be equipped with Chinese medicine extract, can anti-inflammation, fresh breath, long-acting remove removing abnormal flavor in oral cavity.

Description

A kind of collutory and preparation method thereof
Technical field
The invention belongs to oral cleaning nursing article technical field, be specifically related to a kind of collutory and preparation method thereof.
Background technology
Along with the raising of living standards of the people, oral hygiene has obtained great attention.Oral cavity is the hotbed of antibacterial, brushes teeth It is only capable of cleaning part dental surface, back and teeth space are difficult to clean, the food debris of easily accumulation residual, thus promote thin The existence of bacterium;Food debris is decomposed generation volatile sulfur compound by antibacterial, including hydrogen sulfide, methyl mercaptan, double methyl sulfur Alcohol etc..Above-mentioned sulfur-containing compound is the source of halitosis, reduces sulfur-containing compound in oral cavity and can effectively eliminate halitosis.
Collutory is as a kind of method in cleaning oral cavity easily and fast, currently used more and more extensive, simultaneously also can be relatively Good makes up the defect that can not use toothpaste whenever and wherever possible.But the most common collutory contains ethanol, has oral mucosa Certain zest.And majority only has the effect of of short duration removal implication, it is impossible to long-acting remove removing abnormal flavor in oral cavity.
Summary of the invention
For above-mentioned deficiency of the prior art, the invention provides one not spirituosity, do not stimulate oral cavity and can be long-acting Keep collutory of oral cavity fresh and cool and preparation method thereof.
It is to provide one of for achieving the above object a kind of collutory, present invention employs techniques below scheme:
A kind of collutory, including the raw material of following mass fraction:
Antibacterial 0.1%~5%;
Chinese medicine extract 0.1%~5%;
Glycerol 2%~10%;
Deionized water surplus.
Preferably, including the raw material of following mass fraction:
Antibacterial 0.2%~3%;
Chinese medicine extract 0.5%~4%;
Glycerol 5%~10%;
Deionized water surplus.
Further, described antibacterial is chlorine dioxide and/or hydrogen peroxide.
Further, described Chinese medicine extract includes Flos Lonicerae, mentha leave, Radix Glycyrrhizae, Flos Chrysanthemi, Flos Caryophylli.
Further, in terms of mass fraction, described Chinese medicine extract includes:
Flos Lonicerae 3~5 parts;
Mentha leave 2~4 parts;
Radix Glycyrrhizae 3~5 parts;
Flos Chrysanthemi 4~9 parts;
Flos Caryophylli 3~9 parts.
Further, the preparation method of described Chinese medicine extract is as follows:
S1, weigh Flos Lonicerae respectively by proportioning, mentha leave, Radix Glycyrrhizae, Flos Chrysanthemi, Flos Caryophylli, pulverize in pulverizer;
S2, mince middle addition deionized water to Chinese medicine powder, supersound extraction certain time;
S3, lyophilizing extracting solution, obtain Chinese medicine extract powder.
Further, in preparation process S2 of Chinese medicine extract, Chinese medicine is 1:20~1 with the mass ratio of deionized water: 50。
Further, in preparation process S2 of Chinese medicine extract, ultrasonic power is 50W~200W, and ultrasonic time is 20min~2h.
Present invention also offers the preparation method of above-mentioned collutory, in terms of mass fraction, comprise the steps:
S1, weigh a certain amount of deionized water, add the antibacterial chlorine dioxide of 0.1%~5%, be evenly stirred until completely Dissolve;
S2, the Chinese medicine extract of addition 0.1%~5%, be evenly stirred until and be completely dissolved;
S3, the glycerol of addition 2%~10%, stirring is to being completely dissolved;
S4, completion deionized water, stir;
S5, fill get product.
The beneficial effects of the present invention is:
1) present invention is with oxidant as antibacterial, is reacted with volatile sulfur compounds in oral cavity by Oxidation, generates nothing Taste product, (concrete chemical reaction process is similar to H in the generation of donsole cavity foreign flavor2O2+H2S=2H2O+S);Simultaneously with Flos Lonicerae, Mentha leave, Radix Glycyrrhizae, Flos Chrysanthemi, the preparation of Flos Caryophylli Chinese medicine of the five flavours extract, anti-inflammation, fresh breath, it is possible to long-acting removal oral cavity (Flos Lonicerae, heat-clearing and toxic substances removing, wind-heat dissipating, sweet in the mouth is cold in nature, fragrant odour for abnormal flavour;Mentha leave, all diseases of throat, ability to speak, control scrofula Scrofula, skin ulcer scabies, wind scabies urticaria;Radix Glycyrrhizae, QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, coordinating the actions of various ingredients in a prescription;Flos Chrysanthemi, taste Sweet, cool, dispelling wind, heat clearing away, removing toxic substances;Flos Caryophylli, controls implication, regurgitation, treats kidney qi, sensation of gas rushing, pain over the perineum, tonifying YANG, warm waist knee joint, kills alcoholism, Disappear mass beside the umbilicus, except consumptive disease with cold nature).
2) Chinese medicine extract of the present invention is in preparation process, using deionized water as extracting solution, is extracted by ultrasonic, Simple to operate, extraction time is short.When avoiding the alcohol extract later stage to prepare collutory, it is necessary to carry out ethanol dissolving;Thus prepare not Spirituosity, removable halitosis, the collutory of long-acting fresh breath, have and do not stimulate without ethanol the uniqueness of oral mucosa excellent Gesture.
Detailed description of the invention
Below in conjunction with the embodiment of the present invention, the technical scheme in the present invention is clearly and completely described.Following reality Execute example and be only used for clearly illustrating technical scheme, and can not limit the scope of the invention with this.
A kind of collutory
Raw material including following mass fraction:
Antibacterial 0.1%~5%;
Chinese medicine extract 0.1%~5%;
Glycerol 2%~10%;
Deionized water surplus.
As one preferred embodiment, described collutory includes the raw material of following mass fraction:
Antibacterial 0.2%~3%;
Chinese medicine extract 0.5%~4%;
Glycerol 5%~10%;
Deionized water surplus.
Wherein, described antibacterial is chlorine dioxide and/or hydrogen peroxide.Described Chinese medicine extract includes Flos Lonicerae, Herba Menthae Leaf, Radix Glycyrrhizae, Radix Notoginseng, Flos Chrysanthemi, Flos Caryophylli.
In terms of mass fraction, the proportioning of described Chinese medicine extract is as follows:
Flos Lonicerae 3~5 parts;
Mentha leave 2~4 parts;
Radix Glycyrrhizae 3~5 parts;
Flos Chrysanthemi 4~9 parts;
Flos Caryophylli 3~9 parts.
A kind of preparation method of collutory
In terms of mass fraction, comprise the steps:
S1, weigh a certain amount of deionized water, add the antibacterial of 0.1%~5%, be evenly stirred until and be completely dissolved;
S2, the Chinese medicine extract of addition 0.1%~5%, be evenly stirred until and be completely dissolved;
S3, the glycerol of addition 2%~10%, stirring is to being completely dissolved;
S4, completion deionized water, stir;
S5, fill get product.
Embodiment 1
One, the preparation method of the Chinese medicine extract added in collutory:
S1, weigh Flos Lonicerae 3g, mentha leave 4g, Radix Glycyrrhizae 3g, Radix Notoginseng 5g, Flos Chrysanthemi 8g, Flos Caryophylli 4g, powder in pulverizer Broken;
S2, above-mentioned ground product add 540ml ionized water, 100W supersound extraction 1h;
S3, lyophilizing extracting solution, obtain Chinese medicine extract powder.
Two, using the Chinese medicine extract of above-mentioned preparation, collutory includes the raw material of following content:
Three, the preparation method of above-mentioned collutory, comprises the steps:
S1, weigh the deionized water of 50g, add antibacterial chlorine dioxide 0.5g, stir, to being completely dissolved;
S2, addition Chinese medicine extract 3g, be evenly stirred until and be completely dissolved;
S3, addition glycerol 5g, stirring is to being completely dissolved;
S4, completion deionized water 41.5g, stir;
S5, fill get product.
Embodiment 2
One, the preparation method of the Chinese medicine extract added in collutory:
S1, weigh Flos Lonicerae 5g, mentha leave 2g, Radix Glycyrrhizae 4g, Flos Chrysanthemi 5g, Flos Caryophylli 3g, pulverize in pulverizer;
S2, above-mentioned ground product add 700ml deionized water, 50W supersound extraction 30min;
S3, lyophilizing extracting solution, obtain Chinese medicine extract powder.
Two, using the Chinese medicine extract of above-mentioned preparation, collutory includes the raw material of following content:
Three, the preparation method of above-mentioned collutory, comprises the steps:
S1, weigh the deionized water of 50g, add antibacterial hydrogen peroxide 3g, stir, to being completely dissolved;
S2, addition Chinese medicine extract 4g, be evenly stirred until and be completely dissolved;
S3, addition glycerol 10g, stirring is to being completely dissolved;
S4, completion deionized water 33g, stir;
S5, fill get product.
Embodiment 3
One, the preparation method of the Chinese medicine extract added in collutory:
S1, weigh Flos Lonicerae 4g, mentha leave 3g, Radix Glycyrrhizae 4g, Flos Chrysanthemi 6g, Flos Caryophylli 9g, pulverize in pulverizer;
S2, above-mentioned ground product add 1700ml deionized water, 200W supersound extraction 2h;
S3, lyophilizing extracting solution, obtain Chinese medicine extract powder.
Two, using the Chinese medicine extract of above-mentioned preparation, collutory includes the raw material of following content:
Three, the preparation method of above-mentioned collutory, comprises the steps:
S1, weigh the deionized water of 50g, add antibacterial chlorine dioxide 1g, stir, to being completely dissolved;
S2, addition Chinese medicine extract 0.5g, be evenly stirred until and be completely dissolved;
S3, addition glycerol 8g, stirring is to being completely dissolved;
S4, completion deionized water 40.5g, stir;
S5, fill get product.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art For Yuan, on the premise of without departing from the technology of the present invention principle, it is also possible to make some improvement and deformation, these improve and deformation Also should be regarded as protection scope of the present invention.

Claims (9)

1. a collutory, it is characterised in that include the raw material of following mass fraction:
Antibacterial 0.1%~5%;
Chinese medicine extract 0.1%~5%;
Glycerol 2%~10%;
Deionized water surplus.
A kind of collutory the most according to claim 1, it is characterised in that include the raw material of following mass fraction:
Antibacterial 0.2%~3%;
Chinese medicine extract 0.5%~4%;
Glycerol 5%~10%;
Deionized water surplus.
A kind of collutory the most according to claim 1 and 2, it is characterised in that: described antibacterial is chlorine dioxide and/or oxygen Change hydrogen.
A kind of collutory the most according to claim 1 and 2, it is characterised in that: described Chinese medicine extract includes Flos Lonicerae, thin Folium Nelumbinis, Radix Glycyrrhizae, Flos Chrysanthemi, Flos Caryophylli.
A kind of collutory the most according to claim 4, it is characterised in that in terms of mass fraction, described Chinese medicine extract bag Include:
Flos Lonicerae 3~5 parts;
Mentha leave 2~4 parts;
Radix Glycyrrhizae 3~5 parts;
Flos Chrysanthemi 4~9 parts;
Flos Caryophylli 3~9 parts.
A kind of collutory the most according to claim 5, it is characterised in that the preparation method of described Chinese medicine extract is as follows:
S1, weigh Flos Lonicerae respectively by proportioning, mentha leave, Radix Glycyrrhizae, Flos Chrysanthemi, Flos Caryophylli, pulverize in pulverizer;
S2, mince middle addition deionized water to Chinese medicine powder, supersound extraction certain time;
S3, lyophilizing extracting solution, obtain Chinese medicine extract powder.
A kind of collutory the most according to claim 6, it is characterised in that: in preparation process S2 of Chinese medicine extract, in Medicine is 1:20~1:50 with the mass ratio of deionized water.
A kind of collutory the most according to claim 6, it is characterised in that: in preparation process S2 of Chinese medicine extract, super Acoustical power is 50W~200W, and ultrasonic time is 20min~2h.
9. the preparation method of a collutory, it is characterised in that in terms of mass fraction, comprise the steps:
S1, weigh a certain amount of deionized water, add the antibacterial of 0.1%~5%, be evenly stirred until and be completely dissolved;
S2, the Chinese medicine extract of addition 0.1%~5%, be evenly stirred until and be completely dissolved;
S3, the glycerol of addition 2%~10%, stirring is to being completely dissolved;
S4, completion deionized water, stir;
S5, fill get product.
CN201610783557.6A 2016-08-30 2016-08-30 A kind of collutory and preparation method thereof Pending CN106109366A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106473997A (en) * 2016-12-21 2017-03-08 广州姿采化妆品厂 A kind of antibacterial mouthwash in nursing oral cavity and preparation method thereof
CN107242993A (en) * 2017-06-23 2017-10-13 王会海 A kind of spearmint ferment mouthwash and preparation method thereof
CN108392460A (en) * 2018-05-23 2018-08-14 安徽广生堂生物科技有限公司 A kind of Chinese prescription extraction mouth cleaning solution and its manufacturing method
CN110638672A (en) * 2019-09-16 2020-01-03 陈秋迎 Mouthwash for oral examination or treatment
WO2020227422A1 (en) * 2019-05-06 2020-11-12 Greenology Products, Llc Plant extract compositions

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CN101897658A (en) * 2010-07-02 2010-12-01 中国科学院广州生物医药与健康研究院 Mouth rinse for removing halitosis and preparation method thereof
CN105832592A (en) * 2016-03-28 2016-08-10 北京世纪鸿成商贸有限公司 Multiple-effect mouthwash

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* Cited by examiner, † Cited by third party
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CN101780016A (en) * 2009-01-16 2010-07-21 上海交通大学医学院附属第九人民医院 Compound formula mouth wash of chlorine dioxide, cetylpyridinium chloride and zinc ion and preparation method thereof
CN101829027A (en) * 2010-05-11 2010-09-15 李少君 Multifunctional gargle and its preparation method
CN101897658A (en) * 2010-07-02 2010-12-01 中国科学院广州生物医药与健康研究院 Mouth rinse for removing halitosis and preparation method thereof
CN105832592A (en) * 2016-03-28 2016-08-10 北京世纪鸿成商贸有限公司 Multiple-effect mouthwash

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106473997A (en) * 2016-12-21 2017-03-08 广州姿采化妆品厂 A kind of antibacterial mouthwash in nursing oral cavity and preparation method thereof
CN107242993A (en) * 2017-06-23 2017-10-13 王会海 A kind of spearmint ferment mouthwash and preparation method thereof
CN107242993B (en) * 2017-06-23 2020-07-31 王会海 Spearmint enzyme mouthwash and preparation method thereof
CN108392460A (en) * 2018-05-23 2018-08-14 安徽广生堂生物科技有限公司 A kind of Chinese prescription extraction mouth cleaning solution and its manufacturing method
WO2020227422A1 (en) * 2019-05-06 2020-11-12 Greenology Products, Llc Plant extract compositions
CN110638672A (en) * 2019-09-16 2020-01-03 陈秋迎 Mouthwash for oral examination or treatment

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Application publication date: 20161116