CN104800117A - Traditional Chinese medicine toothpaste for resisting diabetic periodontitis and preparation method of toothpaste - Google Patents
Traditional Chinese medicine toothpaste for resisting diabetic periodontitis and preparation method of toothpaste Download PDFInfo
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Abstract
The invention discloses traditional Chinese medicine toothpaste for resisting diabetic periodontitis and a preparation method of the toothpaste. The toothpaste for resisting the diabetic periodontitis comprises components by weight as follows: 40-50 parts of dibasic sodium phosphate, 1-4 parts of silicon dioxide, 10-20 parts of glycerin, 0.5-2.5 parts of sodium carboxymethyl cellulose, 0.1-0.5 parts of carrageenan, 1-2 parts of sodium lauryl sulfate, 0.05-0.15 parts of saccharin sodium, 0.5-3.5 parts of a medicine extract, 0.01-0.05 parts of perfume, 0.005-0.02 parts of ethyl 4-hydroxybenzoate and 30-40 parts of water for injection. The preparation method of the traditional Chinese medicine toothpaste comprises steps of preparation of the medicine extract, material mixing, stirring, grinding, degassing and the like. The prepared traditional Chinese medicine toothpaste can be used for treating the diabetic periodontitis, has effects of clearing heat, removing toxicity, eliminating and treating ulcers, activating blood circulation and removing blood stasis and is free of toxic and side effects.
Description
Technical field
The invention belongs to household chemicals field, relate to a kind of Chinese medicinal toothpaste and preparation method thereof, particularly relate to Chinese medicinal toothpaste of a kind of anti-diabetic periodontitis and preparation method thereof.
Background technology
Periodontitis, be the chronic inflammatory disease invading gingiva and periodontal tissue, being a kind of destructive disease, is the main cause causing adult's loss of tooth.According to investigations, the prevalence of China adult periodontitis is up to 80% ~ 90%.The great discovery of medical research is in recent years that periodontitis not only involves periodontal tissue, and the whole body health of serious harm people, the relation of periodontitis and whole body health has been the focus of attention of domestic and international medical expert and oral expert, especially the relation of periodontitis and diabetes.At present, along with the acceleration of living-pattern preservation and aging process, the prevalence of China's diabetes is in quick ascendant trend, and the periodontitis relevant to the age is as oral cavity commonly encountered diseases and frequently-occurring disease, also has sickness rate to increase trend gradually.The number of the diabetics of going to a doctor at periodontal training in recent years constantly rises.Some patient, because periodontitis, periodontal abscess and going to a doctor, not only suffers from periodontal disease on inspection but also suffers from diabetes.Much research has confirmed that " two-way " of diabetes and periodontitis promotes relation, diabetes are risk factors of periodontitis on the one hand, periodontitis has negative effect as the Metabolism control of chronic inflammatory disease to diabetes on the other hand, and existing scholar proposes the 6th complication that periodontitis is diabetes.Although periodontitis is the local infection of periodontal tissue, by the impact of systemic factor, and show the inflammatory reaction of whole body.Nearest research finds that the level of c reactive protein, Interleukin-6 and tumor necrosis factor in the serum of patients with periodontitis can raise, and these inflammatory factors reduce insulin sensitivity, affect in glycemic control and change lipid metabolism and plays an important role.Therefore periodontitis is as the very high diseases associated with inflammation of prevalence, probably threatens the whole body health of host potentially.
At present, the treatment of periodontitis is based on topical therapeutic, first be the tartar (being medically called supragingival calculus) above removing gingiva, then the tartar (i.e. subgingival calculus) in periodontal pocket is removed, and strike off in periodontal pocket containing a large amount of bacteriotoxic pathological changes cementum, after these treatments, red swelling of gingiva can disappear, and gingival hemorrhage and purulent discharge of pocket can disappear.Wherein, can patient adhere to that good self-bacterial plaque controls, and is the key controlling cementopathia.But up to now, the control of bacterial plaque mainly relies on oral broad ectrum antibiotic to complete, especially metronidazole and tinidazole, is the first-selected medication of periodontitis for a long time always.But the severest consequences that the prolonged application of broad ectrum antibiotic is brought are exactly drug resistance, even cause superinfection.Especially the latter, even more serious to the harm of diabetes patient.Therefore, the present invention, from traditional medicine treasure-house, in conjunction with modern medicines preparation process, has made a kind of Chinese medicinal toothpaste preparation of anti-diabetic periodontitis.
Summary of the invention
The technical problem solved: the object of the invention is to provide a kind of preparation technology with the Chinese medicinal toothpaste of anti-diabetic periodontitis.The clinical manifestation of diabetic periodontitis is with red swelling of gingiva, pain, and easily hemorrhage and blood stasis, periodontal pyorrhea, halitosis, thirst with desire to drink is main manifestations.For this symptom, control suitable heat-clearing and toxic substances removing, dissipate and treat skin ulcer.
Technical scheme: the invention discloses Chinese medicinal toothpaste of a kind of anti-diabetic periodontitis and preparation method thereof, the Chinese medicinal toothpaste of described anti-diabetic periodontitis comprises following composition by weight:
Dibastic sodium phosphate 40-50 part,
Silica 1-4 parts,
Glycerol 10-20 part,
Sodium carboxymethyl cellulose 0.5-2.5 part,
Carrageenin 0.1-0.5 part,
Sodium lauryl sulfate 1-2 part,
Saccharin sodium 0.05-0.15 part,
Drug extract 0.5-3.5 part,
Spice 0.01-0.05 part,
Ethylparaben 0.005-0.02 part,
Water for injection 30-40 part.
Preferably, the Chinese medicinal toothpaste of described anti-diabetic periodontitis comprises following composition by weight:
Dibastic sodium phosphate 45 parts,
Silicon dioxide 2 parts,
Glycerol 15 parts,
Sodium carboxymethyl cellulose 1 part,
Carrageenin 0.3 part,
Sodium lauryl sulfate 1.5 parts,
Saccharin sodium 0.1 part,
Drug extract 2 parts,
Spice 0.03 part,
Ethylparaben 0.01 part,
Water for injection 35 parts.
The preparation method of the Chinese medicinal toothpaste of described anti-diabetic periodontitis is as follows:
(1) extracting honeysuckle is 3 parts respectively by weight, Herba Violae is 5 parts, Radix Scutellariae is 4 parts, Herba Taraxaci is 3 parts, Flos Chrysanthemi Indici is 5 parts, Radix Puerariae is 7 parts, Radix Salviae Miltiorrhizae is 8 parts, above-mentioned Chinese crude drug is pulverized, after pulverizing, mix homogeneously obtains mixed-powder, add water and carry out heated and stirred extraction, be concentrated into 2 times that weight is mixed-powder weight after extraction, add the dehydrated alcohol of mixed-powder weight equivalents, leave standstill after stirring, get supernatant, by supernatant concentration to dry, obtain drug extract;
(2) parts by weights another name gets dibastic sodium phosphate 40-50 part, silica 1-4 parts, glycerol 10-20 part, sodium carboxymethyl cellulose 0.5-2.5 part, carrageenin 0.1-0.5 part, sodium lauryl sulfate 1-2 part, saccharin sodium 0.05-0.15 part, drug extract 0.5-3.5 part, spice 0.01-0.05 part, ethylparaben 0.005-0.02 part, water for injection 30-40 part;
(3) by glycerol, sodium carboxymethyl cellulose input glue pot, moistening is stirred, then adds saccharin sodium, water for injection, continues to stir, and makes the glue made be that even translucent sticky shape is liquid, then stores, use after allowing it fully dissolve expansion;
(4) again the glue that dibastic sodium phosphate, silicon dioxide, carrageenin, sodium lauryl sulfate, drug extract, spice and ethylparaben and step (3) prepare is dropped into block and close in pot, stirred by mechanical mixture, make mastic;
(5) ground through grinder by mastic, a grinding point secondary carries out, and the rear storage of first time mill, will carry out vacuum outgas after second time grinding, until vacuum reaches 0.096Mpa, the time is 50 minutes, prepares product after degassed.
Wherein, the water adding mixed-powder weight 10 times when preparation method step (1) the Chinese medicine extractum of the Chinese medicinal toothpaste of described anti-diabetic periodontitis extracts carries out heated and stirred extraction, and Extracting temperature is 60 DEG C, and extraction time is 3h.
Preferably, preparation method step (2) the Chinese medicine extractum of the Chinese medicinal toothpaste of described anti-diabetic periodontitis is 1-3 part.
Preferably, preparation method step (2) the Chinese medicine extractum of the Chinese medicinal toothpaste of described anti-diabetic periodontitis is 2 parts.
Beneficial effect: the Chinese medicinal toothpaste adopting the inventive method to prepare has heat-clearing and toxic substances removing, dissipates and treat effect of skin ulcer, blood circulation promoting and blood stasis dispelling, blood stasis dispersing and fresh blood promoting, removing heat from blood eliminating carbuncle, is pure Chinese medicinal preparation, has no side effect, do not have drug resistance, also can not cause superinfection.For diabetes patient, when some antibiotic should not be used, the party is used to seem more suitable.Full side is made up of Flos Lonicerae, Herba Violae, Radix Scutellariae, Herba Taraxaci, Flos Chrysanthemi Indici, Radix Puerariae and Radix Salviae Miltiorrhizae seven flavor medicine, carrys out the treatment for diabetic periodontitis.This 7 taste Chinese medicine is extracted drug extract according to a certain ratio, reproduces for pharmaceutical preparation technology, be prepared into toothpaste preparation.
Detailed description of the invention
Embodiment 1
(1) extracting honeysuckle is 3 parts respectively by weight, Herba Violae is 5 parts, Radix Scutellariae is 4 parts, Herba Taraxaci is 3 parts, Flos Chrysanthemi Indici is 5 parts, Radix Puerariae is 7 parts, Radix Salviae Miltiorrhizae is 8 parts, above-mentioned Chinese crude drug is pulverized, after pulverizing, mix homogeneously obtains mixed-powder, add water and carry out heated and stirred extraction, the water adding mixed-powder weight 10 times carries out heated and stirred extraction, Extracting temperature is 60 DEG C, extraction time is 3h, 2 times that weight is mixed-powder weight are concentrated into after extraction, add the dehydrated alcohol of mixed-powder weight equivalents, leave standstill after stirring, get supernatant, by supernatant concentration to dry, obtain drug extract,
(2) parts by weights another name gets dibastic sodium phosphate 50 parts, silica 1 part, glycerol 20 parts, sodium carboxymethyl cellulose 2.5 parts, carrageenin 0.5 part, sodium lauryl sulfate 2 parts, saccharin sodium 0.05 part, drug extract 3.5 parts, spice 0.01 part, ethylparaben 0.02 part, water for injection 30 parts;
(3) by glycerol, sodium carboxymethyl cellulose input glue pot, moistening is stirred, then adds saccharin sodium, water for injection, continues to stir, and makes the glue made be that even translucent sticky shape is liquid, then stores, use after allowing it fully dissolve expansion;
(4) again the glue that dibastic sodium phosphate, silicon dioxide, carrageenin, sodium lauryl sulfate, drug extract, spice and ethylparaben and step (3) prepare is dropped into block and close in pot, stirred by mechanical mixture, make mastic;
(5) ground through grinder by mastic, a grinding point secondary carries out, and the rear storage of first time mill, will carry out vacuum outgas after second time grinding, until vacuum reaches 0.096Mpa, the time is 50 minutes, prepares product after degassed.
Diabetic patients with periodontitis is after brushing teeth 15 days with the Chinese medicinal toothpaste of embodiment 1, and cure rate is 85%.
Embodiment 2
(1) extracting honeysuckle is 3 parts respectively by weight, Herba Violae is 5 parts, Radix Scutellariae is 4 parts, Herba Taraxaci is 3 parts, Flos Chrysanthemi Indici is 5 parts, Radix Puerariae is 7 parts, Radix Salviae Miltiorrhizae is 8 parts, above-mentioned Chinese crude drug is pulverized, after pulverizing, mix homogeneously obtains mixed-powder, add water and carry out heated and stirred extraction, the water adding mixed-powder weight 10 times carries out heated and stirred extraction, Extracting temperature is 60 DEG C, extraction time is 3h, 2 times that weight is mixed-powder weight are concentrated into after extraction, add the dehydrated alcohol of mixed-powder weight equivalents, leave standstill after stirring, get supernatant, by supernatant concentration to dry, obtain drug extract,
(2) parts by weights another name gets dibastic sodium phosphate 40 parts, silicon dioxide 4 parts, glycerol 10 parts, sodium carboxymethyl cellulose 0.5 part, carrageenin 0.1 part, sodium lauryl sulfate 1 part, saccharin sodium 0.15 part, drug extract 0.5 part, spice 0.05 part, ethylparaben 0.005 part, water for injection 40 parts;
(3) by glycerol, sodium carboxymethyl cellulose input glue pot, moistening is stirred, then adds saccharin sodium, water for injection, continues to stir, and makes the glue made be that even translucent sticky shape is liquid, then stores, use after allowing it fully dissolve expansion;
(4) again the glue that dibastic sodium phosphate, silicon dioxide, carrageenin, sodium lauryl sulfate, drug extract, spice and ethylparaben and step (3) prepare is dropped into block and close in pot, stirred by mechanical mixture, make mastic;
(5) ground through grinder by mastic, a grinding point secondary carries out, and the rear storage of first time mill, will carry out vacuum outgas after second time grinding, until vacuum reaches 0.096Mpa, the time is 50 minutes, prepares product after degassed.
Diabetic patients with periodontitis is after brushing teeth 15 days with the Chinese medicinal toothpaste of embodiment 2, and cure rate is 87%.
Embodiment 3
(1) extracting honeysuckle is 3 parts respectively by weight, Herba Violae is 5 parts, Radix Scutellariae is 4 parts, Herba Taraxaci is 3 parts, Flos Chrysanthemi Indici is 5 parts, Radix Puerariae is 7 parts, Radix Salviae Miltiorrhizae is 8 parts, above-mentioned Chinese crude drug is pulverized, after pulverizing, mix homogeneously obtains mixed-powder, add water and carry out heated and stirred extraction, the water adding mixed-powder weight 10 times carries out heated and stirred extraction, Extracting temperature is 60 DEG C, extraction time is 3h, 2 times that weight is mixed-powder weight are concentrated into after extraction, add the dehydrated alcohol of mixed-powder weight equivalents, leave standstill after stirring, get supernatant, by supernatant concentration to dry, obtain drug extract,
(2) parts by weights another name gets dibastic sodium phosphate 45 parts, silicon dioxide 2 parts, glycerol 15 parts, sodium carboxymethyl cellulose 1 part, carrageenin 0.3 part, sodium lauryl sulfate 1.5 parts, saccharin sodium 0.1 part, drug extract 2 parts, spice 0.03 part, ethylparaben 0.01 part, water for injection 35 parts;
(3) by glycerol, sodium carboxymethyl cellulose input glue pot, moistening is stirred, then adds saccharin sodium, water for injection, continues to stir, and makes the glue made be that even translucent sticky shape is liquid, then stores, use after allowing it fully dissolve expansion;
(4) again the glue that dibastic sodium phosphate, silicon dioxide, carrageenin, sodium lauryl sulfate, drug extract, spice and ethylparaben and step (3) prepare is dropped into block and close in pot, stirred by mechanical mixture, make mastic;
(5) ground through grinder by mastic, a grinding point secondary carries out, and the rear storage of first time mill, will carry out vacuum outgas after second time grinding, until vacuum reaches 0.096Mpa, the time is 50 minutes, prepares product after degassed.
Diabetic patients with periodontitis is after brushing teeth 15 days with the Chinese medicinal toothpaste of embodiment 3, and cure rate is 95%.
Comparative example
License notification number is the patent of invention of CN102698097, and patient is after treating with the collutory of comparative example, and the healing of periodontitis is only 74%.
Model case
1. certain female, 59 years old, suffers from diabetes 20 years, the atrophy of gingiva mild redness, and frequent hemorrhage pyorrhea, odontoseisis, thirsty parched throat.With above-mentioned Tooth paste brush tooth after 2 weeks, sb.'s illness took a favorable turn, and swelling and aching of gum disappears, and do not have hemorrhage pyorrhea again.
2. certain man, 62 years old, suffers from diabetes 12 years, gingiva pain on left side, red and swollen, eating difficulties, and with above-mentioned Tooth paste brush tooth, the 5th day pain and facial swelling alleviate to some extent, the 10th, and toothache stops, and left facial part swelling is obviously disappeared.
3. certain man, 49 years old, diabetes 7 years, right side lower teeth slightly loosened, the atrophy of gingiva mild redness, and occasionally has toothache and gingival hemorrhage situation.With above-mentioned Tooth paste brush tooth after 1 week, sb.'s illness took a favorable turn in toothache, and swelling and aching of gum disappears, and gingival hemorrhage situation reduces.
Claims (6)
1. a Chinese medicinal toothpaste for anti-diabetic periodontitis, is characterized in that, the Chinese medicinal toothpaste of described anti-diabetic periodontitis comprises following composition by weight:
Dibastic sodium phosphate 40-50 part,
Silica 1-4 parts,
Glycerol 10-20 part,
Sodium carboxymethyl cellulose 0.5-2.5 part,
Carrageenin 0.1-0.5 part,
Sodium lauryl sulfate 1-2 part,
Saccharin sodium 0.05-0.15 part,
Drug extract 0.5-3.5 part,
Spice 0.01-0.05 part,
Ethylparaben 0.005-0.02 part,
Water for injection 30-40 part.
2. the Chinese medicinal toothpaste of anti-diabetic periodontitis according to claim 1, is characterized in that, comprises following composition by weight:
Dibastic sodium phosphate 45 parts,
Silicon dioxide 2 parts,
Glycerol 15 parts,
Sodium carboxymethyl cellulose 1 part,
Carrageenin 0.3 part,
Sodium lauryl sulfate 1.5 parts,
Saccharin sodium 0.1 part,
Drug extract 2 parts,
Spice 0.03 part,
Ethylparaben 0.01 part,
Water for injection 35 parts.
3. the preparation method of the Chinese medicinal toothpaste of a kind of anti-diabetic periodontitis according to claim 1, it is characterized in that, step is as follows:
(1) extracting honeysuckle is 3 parts respectively by weight, Herba Violae is 5 parts, Radix Scutellariae is 4 parts, Herba Taraxaci is 3 parts, Flos Chrysanthemi Indici is 5 parts, Radix Puerariae is 7 parts, Radix Salviae Miltiorrhizae is 8 parts, above-mentioned Chinese crude drug is pulverized, after pulverizing, mix homogeneously obtains mixed-powder, add water and carry out heated and stirred extraction, be concentrated into 2 times that weight is mixed-powder weight after extraction, add the dehydrated alcohol of mixed-powder weight equivalents, leave standstill after stirring, get supernatant, by supernatant concentration to dry, obtain drug extract;
(2) parts by weights another name gets dibastic sodium phosphate 40-50 part, silica 1-4 parts, glycerol 10-20 part, sodium carboxymethyl cellulose 0.5-2.5 part, carrageenin 0.1-0.5 part, sodium lauryl sulfate 1-2 part, saccharin sodium 0.05-0.15 part, drug extract 0.5-3.5 part, spice 0.01-0.05 part, ethylparaben 0.005-0.02 part, water for injection 30-40 part;
(3) by glycerol, sodium carboxymethyl cellulose input glue pot, moistening is stirred, then adds saccharin sodium, water for injection, continues to stir, and makes the glue made be that even translucent sticky shape is liquid, then stores, use after allowing it fully dissolve expansion;
(4) again the glue that dibastic sodium phosphate, silicon dioxide, carrageenin, sodium lauryl sulfate, drug extract, spice and ethylparaben and step (3) prepare is dropped into block and close in pot, stirred by mechanical mixture, make mastic;
(5) ground through grinder by mastic, a grinding point secondary carries out, and the rear storage of first time mill, will carry out vacuum outgas after second time grinding, until vacuum reaches 0.096Mpa, the time is 50 minutes, prepares product after degassed.
4. the preparation method of the Chinese medicinal toothpaste of a kind of anti-diabetic periodontitis according to claim 3, it is characterized in that, step (1) Chinese medicine extractum adds mixed-powder weight 10 times water when extracting carries out heated and stirred extraction, and Extracting temperature is 60 DEG C, and extraction time is 3h.
5. the preparation method of the Chinese medicinal toothpaste of a kind of anti-diabetic periodontitis according to claim 3, is characterized in that, step (2) Chinese medicine extractum is 1-3 part.
6. the preparation method of the Chinese medicinal toothpaste of a kind of anti-diabetic periodontitis according to claim 3, is characterized in that, preparation method step (2) Chinese medicine extractum is 2 parts.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726792A (en) * | 2016-02-25 | 2016-07-06 | 南京中医药大学 | Traditional Chinese medicine composition with effects of resisting periodontitis and protecting periodontium and preparation method and application thereof |
| CN107412064A (en) * | 2017-08-15 | 2017-12-01 | 何家平 | A kind of Chinese herbal toothpaste |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110229534A1 (en) * | 2006-10-05 | 2011-09-22 | The Trustees Of Columbia University In The City Of New York | Non-Irritating Oral Care Formulations |
| CN102755455A (en) * | 2012-08-11 | 2012-10-31 | 杨献华 | Care solution for oral mucosa ulcer |
| CN102973453A (en) * | 2011-09-07 | 2013-03-20 | 沈新荣 | Medicated toothpaste and preparation method thereof |
-
2015
- 2015-04-16 CN CN201510178858.1A patent/CN104800117A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110229534A1 (en) * | 2006-10-05 | 2011-09-22 | The Trustees Of Columbia University In The City Of New York | Non-Irritating Oral Care Formulations |
| CN102973453A (en) * | 2011-09-07 | 2013-03-20 | 沈新荣 | Medicated toothpaste and preparation method thereof |
| CN102755455A (en) * | 2012-08-11 | 2012-10-31 | 杨献华 | Care solution for oral mucosa ulcer |
Non-Patent Citations (2)
| Title |
|---|
| 向敏等: "加味五味消毒饮提取物对糖尿病大鼠牙周炎的抑制作用", 《抗感染药学》 * |
| 向敏等: "加味五味消毒饮提取物对糖尿病大鼠牙周组织的保护作用", 《中国临床药理学与治疗学》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105726792A (en) * | 2016-02-25 | 2016-07-06 | 南京中医药大学 | Traditional Chinese medicine composition with effects of resisting periodontitis and protecting periodontium and preparation method and application thereof |
| CN107412064A (en) * | 2017-08-15 | 2017-12-01 | 何家平 | A kind of Chinese herbal toothpaste |
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Application publication date: 20150729 |