CN108309843A - It is a kind of to have effects that purify the composition and its preparation method and application of pore - Google Patents
It is a kind of to have effects that purify the composition and its preparation method and application of pore Download PDFInfo
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- CN108309843A CN108309843A CN201810114146.7A CN201810114146A CN108309843A CN 108309843 A CN108309843 A CN 108309843A CN 201810114146 A CN201810114146 A CN 201810114146A CN 108309843 A CN108309843 A CN 108309843A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/008—Preparations for oily skin
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Abstract
Have effects that purify the composition and its preparation method and application of pore the invention discloses a kind of.The present composition is grouped as by following group by mass percentage：The deep layer cleaning factor 10%~20%, the convergence pore factor 10%~20%, antiallergic of the releiving factor 5%~10%, polyalcohol 5%~15%, water surplus.The deep layer cleaning factor, the convergence pore factor, antiallergic of the releiving factor and polyalcohol in the present composition have synergistic function, and it is concentrated type plant extracts, it does not stimulate mildly, it can purify and dredge pore, adjust fat secretion, the dirt for removing pore depths has the function that releive skin, conditioning and repairs oily skin and Combination skin, has a good application prospect.
Description
Technical field
The invention belongs to cosmetic technical fields, it is more particularly related to which a kind of have effects that purify pore
Composition and its preparation method and application.
Background technology
With the age increases, social pressures are excessive, environmental pollution, computer radiation the problems such as it is increasingly severe, therewith to skin
Skin causes many harmful effects, and the people of combination is more and more, in addition to some are born combination, also one
Groups of people are with pressure and the combination that becomes, also before be neutral skin or Oily also can with the age,
Environment etc. becomes combination.
Sebum be by skin inside sebocyte cell generate, be then secreted into the oil of skin surface.Combination or oil
Property skin formation precisely due to caused by skin oil and fat hypersecretion, fat secretion is excessive, the support of grease that pore can be stacked
Greatly.Pore is coarse to be often as excessive hormone in vivo parasecretion, pressure and the reasons such as environmental pollution, cleaning are not carried out
Caused by.In addition, with advancing age, skin gradually loses elasticity, perifollicolar lacks support construction, is also easy to make hair
Hole seems bigger；Coarse pore is the greatest problem for perplexing oiliness and mixing skin.In addition, sunshine is reinforced, metabolism adds
The factors such as fast cause skin ingress of oil more vigorous, and pore may appear to become apparent from.
Excessive grease is deposited in pore, only can be more more crowded bigger by pore.Grease, which is wrapped in skin, can become hoary hair
Acne；It bursts through and meets air oxidation blackening, will form blackhead, it is more serious or even acne can be deteriorated into.Acne
It is formed, the grease that should be exactly emitted originally from pore, because what the hyperkeratosis blocking of hair aperture periphery was mixed
Product, so, when acne are more accumulated the more, pore also can more be supportted bigger.
Currently, in existing cosmetics, in order to control or regulate sebum secretion, mainly use some Oil suction powders at
Point, such as silica, polymethyl methacrylate, nylon powder, boron nitride powder, talcum, titanium dioxide, zinc oxide, silicon
Body etc..These ingredients are to come from synthetic ingredient or mineralogical composition, other than absorbing the ability of sebum, it is difficult to be had further
Effect.And most of cosmetics on the market mainly utilize the silty such as filling silicide to modify enlarged pores at present
Particle quickly fills up pore, and silty particle is usually also equipped with the optical effects such as soft focus, refraction, and pore is allowed to seem not that
It is apparent, but can not fundamentally change the coarse reality of pore.Separately chemicals ingredient is used to reach reduction skin
Fat generates and reduces the way (for example, by using ingredients such as 5 alpha reductase inhibitors to control fat secretion amount) of pore effect, but its
It is subject to certain restrictions in the expansion for the Cosmetic Market for increasingly advocating natural health.
Therefore, researching and developing a fat secretion but also the natural health cosmetics of pore refining, careful skin of can controlling is
It is necessary to.
Invention content
It is an object of the invention to：Overcome above-mentioned deficiency existing in the prior art, provides a kind of with purification pore work(
Composition of effect and its preparation method and application.
In order to achieve the above-mentioned object of the invention, have effects that purify the composition of pore the present invention provides a kind of, by following
Group by mass percentage is grouped as：The deep layer cleaning factor 10%~20%, the convergence pore factor 10%~20%, releives anti-
The quick factor 5%~10%, polyalcohol 5%~15%, water surplus.
Wherein, the deep layer cleaning factor includes mainly the extract rich in saponins compound, specially soap blade of grass
Any one or the combination of several of them in extract, soapberry extract, European horse-chestnut seed extract, they have natural
Cleaning efficacy, mild and have bioactivity, penetrating power is good, grease that can be effectively in deep layer cleaning skin, to skin irritation
It is small, additionally there are antibacterial beauty, bactericidal antiphlogistic, dandruff-removing itching-relieve, alleviation skin allergy and other effects to human skin；
The convergence pore factor includes mainly the extraction rich in faintly acid ingredient such as tannic acid, tannic acid isoreactivity ingredient
Object, they have certain convergence, can reduce pore, careful consolidation skin, specially hamamelis water, broom Chinese photinia carry
Take any one or the combination of several of them in object, Spiraea ulmaria extract；Wherein hamamelis water is rich in tannic acid, former cyanine
Element, Protoapigenone, essential oil, saponin etc. have excellent astriction and antibacterial effect, can facilitate clean up pore, nourishing of releiving,
It repairs and is damaged skin；Broom Chinese photinia extract can restrain skin, kill containing flavonoids, black bearberry former times, tannin, alkaloid, Chinese photinia element etc.
Bacterium inhibits acne, also has the function of that whitening lightens the stain；Spiraea ulmaria extract contains gallotannic acid and ellagitannic acid,
The activity that can inhibit 5α-reductase reduces the activity of sebaceous glands, and limitation sebum secretion is reduced, and pore refining reduces bacterium and increases
It is raw.
The antiallergic factor of releiving is arbitrary in leaf of Mentha piperita extract, Burdok root P.E in May, Radix Cynanchi Atrati extract
One or more of combinations；Wherein, leaf of Mentha piperita extract is rich in dried peppermint leaf flavanones, can alleviate skin mistake to sensitive skin
Quick symptom has anti-inflammatory, eases pain and effect of releiving, and skin microcirculation inhibition inflammatory symptom is adjusted, keeps skin feel pure and fresh soft
With；May, Burdok root P.E had good antibiotic effect, effectively treats acne and other scytitis, also has skin liter
Temp effect and the discharge for promoting liquid and waste in tissue；Skin caused by Radix Cynanchi Atrati extract is highly resistant to MEA stimulates, suppression
The generation of inflammatory cytokine processed, can effective symptoms such as swelling, fever, rubescent, pain caused by dephlogistication.
Preferably, the polyalcohol is butanediol and 1, any one or two kinds in 2- pentanediols, 1,2- hexylene glycols
Combination, can effectively dissolve the active constituent in plant extracts, promote the absorption of active constituent, also there is certain anti-corrosion to imitate
Fruit, while moisturizing and moisturizing can also be played the role of.
The present invention has effects that the preparation method for purifying the composition of pore is uniformly to mix each component according to proportioning, i.e.,
.
The present invention has effects that the composition for purifying pore can be used for preparing cosmetics.
The present invention also provides a kind of cosmetics, have effects that purify the composition of pore it includes above-mentioned.
Preferably, the content of the composition purify with pore is 0.5~10wt%.
Cosmetics of the present invention can be toner, lotion, Essence, cream, facial mask or mud film etc..In production, makeup
The selection of other components can be carried out according to the routine operation in this field in product.
Compared with the existing technology, the present invention has the advantages that：
(1) it is provided by the invention have effects that purify pore composition by the deep layer cleaning factor, convergence the pore factor and
Antiallergic of the releiving factor acts synergistically, and realizes purification and dredging pore, adjusts fat secretion, removes the dirt of skin pore depths,
Mild convergence pore, skin of releiving have the function that conditioning and repair oily skin and Combination skin.
(2) present invention have effects that purify pore composition mainly by unique concentrated type plant extracts compound and
At, be free of chemical composition, do not stimulate mildly.
Specific implementation mode
In order to make the purpose of the present invention, technical solution and advantageous effects be more clear, with reference to embodiments, to this
Invention is further elaborated.It should be understood that embodiment described in this specification is just for the sake of this hair of explanation
It is bright, be not intended to limit the present invention, parameter, ratio of embodiment etc. can adaptation to local conditions make a choice and substance had no to result
It influences.
Following embodiment each component is purchased in market unless otherwise specified.Wherein, soap leaf extract, leaf of Mentha piperita carry
Object, Burdok root P.E in May is taken to be purchased from Guangzhou Rui Yu Chemical Industry Science Co., Ltd, European horse-chestnut seed extract, soapberry carry
Take object purchase from hundred Hao Bo Co., Ltds of Guangzhou, hamamelis water is purchased from Guangzhou Ao Xue Chemical Co., Ltd.s, broom Chinese photinia
Extract is purchased from the Guangzhou bio tech ltd Nuo Ran, and Spiraea ulmaria extract is purchased from Guangzhou Bi Sheng trade Co., Ltds,
Radix Cynanchi Atrati extract is purchased from Shanghai Han Yan trade Co., Ltds.
Embodiment 1
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soap leaf extract
10g, hamamelis water 20g, leaf of Mentha piperita extract 5g, butanediol 10g, 1,2- pentanediol 5g, water 50g.
Embodiment 2
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soapberry extract 20g,
Broom Chinese photinia extract 10g, May Burdok root P.E 10g, butanediol 3g, 1,2- hexylene glycol 2g, water 55g.
Embodiment 3
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：European horse-chestnut seed extracts
Object 15g, Spiraea ulmaria extract 15g, Radix Cynanchi Atrati extract 8g, butanediol 5g, 1,2- pentanediol 3g, 1,2- hexylene glycol 2g, water
52g。
Embodiment 4
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soap leaf extract 7g,
Soapberry extract 5g, hamamelis water 10g, broom Chinese photinia extract 6g, leaf of Mentha piperita extract 4g, May, radix bardanae extracted
Object 3g, butanediol 5g, 1,2- pentanediol 1g, water 59g.
Embodiment 5
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soapberry extract 8g, Europe
Continent horse chestnut seed extract 8g, hamamelis water 6g, Spiraea ulmaria extract 6g, leaf of Mentha piperita extract 4g, radix cynanchi atrati extraction
Object 4g, butanediol 6g, 1,2- hexylene glycol 4g, water 54g.
Embodiment 6
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soap leaf extract 7g,
European horse-chestnut seed extract 8g, broom Chinese photinia extract 8g, Spiraea ulmaria extract 7g, May Burdok root P.E 3g, radix cynanchi atrati
Extract 5g, butanediol 4g, 1,2- pentanediol 3g, water 55g.
Embodiment 7
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soap leaf extract 6g,
Soapberry extract 6g, European horse-chestnut seed extract 6g, hamamelis water 5g, broom Chinese photinia extract 5g, Spiraea ulmaria carry
Take object 5g, leaf of Mentha piperita extract 3g, May Burdok root P.E 3g, Radix Cynanchi Atrati extract 3g, butanediol 5g, 1,2- pentanediol
2g, 1,2- hexylene glycol 2g, water 49g.
When specifically used, take the preparation of the embodiment of the present invention 1 to 7 has effects that the composition for purifying pore is added to shield
In skin product matrix, have effects that the composition for purifying pore accounts for the 0.5~10% of gained skin care item gross mass.
The present invention has effects that the composition for purifying pore is added in skin care item matrix, can be according to preparing the normal of cosmetics
Technique and auxiliary material are advised, the skin protection cosmetics such as toner, lotion, Essence, cream, facial mask or mud film are prepared into.In production, change
The selection of other components can be carried out according to the routine operation in this field in cosmetic.
In order to better illustrate advantages of the present invention, comparative example and Efficacy experiments are given below：
Comparative example 1
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soap leaf extract 6g,
Soapberry extract 6g, European horse-chestnut seed extract 6g, butanediol 9g, water 73g.
Comparative example 2
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Hamamelis water 5g, broom
Chinese photinia extract 5g, Spiraea ulmaria extract 5g, butanediol 9g, water 76g.
Comparative example 3
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Leaf of Mentha piperita extract 3g,
May Burdok root P.E 3g, Radix Cynanchi Atrati extract 3g, butanediol 9g, water 82g.
Comparative example 4
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soap leaf extract 6g,
Soapberry extract 6g, European horse-chestnut seed extract 6g, hamamelis water 5g, broom Chinese photinia extract 5g, Spiraea ulmaria carry
Take object 5g, butanediol 5g, 1,2- pentanediol 4g, water 58g.
Comparative example 5
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Soap leaf extract 6g,
Soapberry extract 6g, European horse-chestnut seed extract 6g, leaf of Mentha piperita extract 3g, May Burdok root P.E 3g, radix cynanchi atrati
Extract 3g, butanediol 5g, 1,2- pentanediol 4g, water 64g.
Comparative example 6
It is a kind of to have effects that purify the composition of pore, it is uniformly mixed by following components：Hamamelis water 5g, broom
Chinese photinia extract 5g, Spiraea ulmaria extract 5g, leaf of Mentha piperita extract 3g, May Burdok root P.E 3g, Radix Cynanchi Atrati extract
3g, butanediol 5g, 1,2- pentanediol 4g, water 67g.
1 skin irritation of experimental example is tested
The external eye irritations of SN/T 2329-2009-chick chorioallantoic membrane experiment (HET-CAM methods) is quoted, evaluation is implemented
The irritation of the composition of example 1-7 and the composition of comparative example 1-6.The results show that composition and the comparison of embodiment 1-7
Terminal scoring is 0 obtained by the composition of example 1-6, illustrates that the present invention has effects that the composition for purifying pore is safe, non-stimulated.
2 efficacy test of experimental example
Laboratory sample：Experimental group is embodiment 1 to 7, the composition of comparative example 1 to 6 is added to facial treatment milk external-use substrate
Facial treatment milk obtained by middle preparation, wherein having effects that additive amount of the composition for purifying pore in facial treatment milk is 5wt%.
Control group is facial treatment milk external-use substrate.
Experimental method：The subject 140 for selecting age 22-35 Sui, is oiliness and Combination skin, without any skin
Disease and skin allergy history, are divided into 14 groups, every group of 10 people, every group is smeared different test samples respectively.Subject makes sooner or later daily
With a test sample, it is used continuously 8 weeks.
Skin oil and fat test probe (Sebumeter, German CK) test forehead portion is being used before and after using 8 weeks respectively
Position 3 times, is averaged, the oil-control effect for assessing the present composition.Experimental result is shown in Table 1.
Using skin image analyzer test skin pore aperture, selects nose areas as test position, make respectively
With preceding and using being measured after 8 weeks.Selection images same position pore, and analysis obtains pore pore size, for assessing
The present invention has the effect of that the composition pore refining of purification pore effect, concrete outcome are shown in Table 2.
It is primary distinguishing follow-up before and after using 8 weeks.When follow-up, it is bad anti-whether inquiry and observation subject occur
It answers and itself impression of subject is scored, skin is unchanged to make 0 score, is improved according to skins such as hair pore shrinkage, blackhead reductions
Degree makes 1~10 score, makes even respectively, and score value is higher, and it is more apparent to show that skin improves.Concrete outcome is shown in Table 3.
1 oil-control effect of table
| Before use | After 8 weeks | Grease change rate (%) | |
| Embodiment 1 | 111.54±28.08 | 79.63±24.97 | -28.61 |
| Embodiment 2 | 109.66±34.51 | 78.55±23.16 | -28.37 |
| Embodiment 3 | 115.17±39.98 | 81.78±25.48 | -28.99 |
| Embodiment 4 | 110.94±29.37 | 74.09±20.37 | -33.22 |
| Embodiment 5 | 116.34±35.30 | 78.09±24.46 | -32.88 |
| Embodiment 6 | 112.58±30.05 | 75.32±22.07 | -33.10 |
| Embodiment 7 | 113.06±32.54 | 69.22±20.14 | -38.78 |
| Comparative example 1 | 108.47±38.46 | 96.49±25.37 | -11.98 |
| Comparative example 2 | 113.69±37.79 | 102.67±27.18 | -9.69 |
| Comparative example 3 | 114.73±32.38 | 108.22±26.46 | -5.67 |
| Comparative example 4 | 113.56±27.99 | 96.47±23.17 | -15.05 |
| Comparative example 5 | 106.80±29.86 | 92.93±20.26 | -12.99 |
| Comparative example 6 | 117.43±21.97 | 105.16±23.85 | -10.45 |
| Control | 116.34±35.59 | 115.92±31.93 | -0.69 |
Table 2 uses front and back skin pore varying aperture situation
3 skin of table improves situation
| Using giving a mark after 8 weeks | |
| Embodiment 1 | 7.9 |
| Embodiment 2 | 7.5 |
| Embodiment 3 | 7.7 |
| Embodiment 4 | 8.3 |
| Embodiment 5 | 8.6 |
| Embodiment 6 | 8.5 |
| Embodiment 7 | 9.0 |
| Comparative example 1 | 3.1 |
| Comparative example 2 | 3.3 |
| Comparative example 3 | 2.0 |
| Comparative example 4 | 4.2 |
| Comparative example 5 | 3.7 |
| Comparative example 6 | 3.9 |
| Control | 0.4 |
It can be obtained from table 1~3, continue to have effects that purify facial treatment milk made of the composition of pore using the present invention
8 weeks, skin oil and fat secretion can be effectively reduced, pore is reduced, reaches good oil-control effect；The non-someone of user occurs simultaneously
The discomfort phenomenon such as any allergy, redness, itch illustrates that the present invention has effects that the composition for purifying pore is that safety is mild, nothing
Stimulation.
Have effects that purify made of the composition of pore after facial treatment milk using embodiment 1-3, grease slip with
And pore varying aperture rate is apparently higher than the sum of the change rate using facial treatment milk made of the compositions of 1-3 containing comparative example, explanation
The present invention has effects that purify the deep layer cleaning factor, the convergence pore factor and the antiallergic factor of releiving in the composition of pore and has
Synergistic function adjusts fat secretion, removes the dirt of skin pore depths, mildly restrains pore, skin of releiving reaches tune
Reason and the effect for repairing oily skin and Combination skin.
Have effects that purify made of the composition of pore after facial treatment milk using containing embodiment 7, grease slip with
And pore varying aperture rate is maximum, the scoring highest of subject, and be apparently higher than and use 1-6 containing embodiment and comparative example 1-6 groups
Close object made of facial treatment milk as a result, illustrate the present invention have effects that purification pore composition, when soap leaf extract,
The deep layer cleaning factor of three kinds of soapberry extract, European horse-chestnut seed extract ingredient compounding compositions, hamamelis water, broom
The convergence pore factor of three kinds of Chinese photinia extract, Spiraea ulmaria extract ingredient compounding compositions, leaf of Mentha piperita extract, ox in May
The antiallergic factor of releiving of three kinds of burdock root extract, Radix Cynanchi Atrati extract ingredient compounding compositions, the effect that the above Multiple components compound
Fruit is best, the effect of capable of preferably reaching purification and dredge pore.
According to the disclosure and teachings of the above specification, those skilled in the art in the invention can also be to above-mentioned embodiment party
Formula carries out change and modification appropriate.Therefore, the invention is not limited in specific implementation modes disclosed and described above, to this
Some modifications and changes of invention should also be as falling into the scope of the claims of the present invention.In addition, although this specification
In used some specific terms, these terms are merely for convenience of description, does not limit the present invention in any way.
Claims (7)
1. a kind of have effects that purify the composition of pore, which is characterized in that be grouped as by following group by mass percentage：
The deep layer cleaning factor 10%~20%, the convergence pore factor 10%~20%, antiallergic of the releiving factor 5%~10%, polyalcohol 5%
~15%, water surplus；
Wherein, the deep layer cleaning factor is in soap leaf extract, soapberry extract, European horse-chestnut seed extract
Any one or the combination of several of them；
The convergence pore factor be hamamelis water, broom Chinese photinia extract, in Spiraea ulmaria extract any one or
Several combinations；
The antiallergic factor of releiving is any one in leaf of Mentha piperita extract, Burdok root P.E in May, Radix Cynanchi Atrati extract
Or several combination.
2. according to claim 1 have effects that purify the composition of pore, which is characterized in that the polyalcohol is fourth two
The combination of any one or two kinds in alcohol and 1,2- pentanediols, 1,2- hexylene glycols.
3. the preparation method of the composition purify with pore as claimed in claim 1 or 2, which is characterized in that by each group
Point according to proportioning uniformly mixing to get.
4. the application as claimed in claim 1 or 2 for having effects that the composition for purifying pore in preparing cosmetics.
5. a kind of cosmetics, which is characterized in that have effects that purify the composition of pore including as claimed in claim 1 or 2.
6. cosmetics according to claim 5, which is characterized in that the addition of the composition purify with pore
Amount is 0.5~10wt%.
7. cosmetics according to claim 5, which is characterized in that the cosmetics are toner, lotion, Essence, cream
Frost, facial mask or mud film.
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| CN109692135A (en) * | 2019-02-28 | 2019-04-30 | 广东芭薇生物科技股份有限公司 | A kind of composition and its application with pore refining and moisture-keeping efficacy |
| CN110339109A (en) * | 2019-07-05 | 2019-10-18 | 广州品爵生物科技有限公司 | A kind of mild multiple-effect facial cleaner and preparation method thereof |
| CN110339108A (en) * | 2019-07-05 | 2019-10-18 | 广州品爵生物科技有限公司 | A kind of moisturizing efficiently adjusts the facial mask liquid and preparation method thereof of sebum secretion amount |
| CN110354031A (en) * | 2019-07-05 | 2019-10-22 | 广州品爵生物科技有限公司 | A kind of toner and preparation method thereof adjusting skin water and oil balance |
| CN110354030A (en) * | 2019-07-05 | 2019-10-22 | 广州品爵生物科技有限公司 | A kind of composition and preparation method thereof adjusting sebum secretion amount |
| CN110354029A (en) * | 2019-07-05 | 2019-10-22 | 广州品爵生物科技有限公司 | A kind of adjustment type milky lotion and preparation method thereof |
| CN114028295A (en) * | 2021-12-10 | 2022-02-11 | 北京安德普泰医疗科技有限公司 | Antibacterial itching-relieving red-fading acne-removing repairing composition as well as preparation method and application thereof |
| CN114099395A (en) * | 2022-01-05 | 2022-03-01 | 广州辰沐生物科技有限公司 | Multifunctional removable mask and preparation method thereof |
| CN116270365A (en) * | 2023-04-28 | 2023-06-23 | 康博士日化集团有限公司 | Freckle-removing plant extract composition and preparation method and application thereof |
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