CN110051577A - A kind of Essence composition and preparation method thereof applied to head antiallergic anti-inflammatory - Google Patents

A kind of Essence composition and preparation method thereof applied to head antiallergic anti-inflammatory Download PDF

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Publication number
CN110051577A
CN110051577A CN201910315086.XA CN201910315086A CN110051577A CN 110051577 A CN110051577 A CN 110051577A CN 201910315086 A CN201910315086 A CN 201910315086A CN 110051577 A CN110051577 A CN 110051577A
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extract
inflammatory
head
antiallergic
flower extract
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CN201910315086.XA
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江华初
曾宇和
黄寿仙
黄惠先
陈鑫隆
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Guangzhou Cohen Biotechnology Co Ltd
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Guangzhou Cohen Biotechnology Co Ltd
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Priority to CN201910315086.XA priority Critical patent/CN110051577A/en
Publication of CN110051577A publication Critical patent/CN110051577A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/342Alcohols having more than seven atoms in an unbroken chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/63Steroids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/735Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/005Preparations for sensitive skin

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Emergency Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

A kind of Essence composition applied to head antiallergic anti-inflammatory, is made of the following components: water, Sodium Hyaluronate, D-pantothenyl aleohol, allantoin, Gotu Kola P.E, dipotassium glycyrrhizinate, purslane extract, Astragalus membranacus root extract, pot marigold flower extract, german chamomile flower extract, Geranium Essential, bisabolol, pentanediol;Water, EDTA-2Na, carbomer, xanthan gum, butanediol, Sodium Hyaluronate, allantoin in raw material: (1) being added in emulsion pot by its preparation step, is heated to 80 degree, insulated and stirred 15 minutes, obtains mixture.(2) mixture in emulsion pot is cooled to 45 degrees Celsius, D-pantothenyl aleohol, dipotassium glycyrrhizinate, purslane extract, Astragalus membranacus root extract, pot marigold flower extract, Gotu Kola P.E, german chamomile flower extract, bisabolol, Geranium Essential, pentanediol is added, is uniformly mixing to obtain finished product.The present invention has the effect of good antiallergic anti-inflammatory.

Description

A kind of Essence composition and preparation method thereof applied to head antiallergic anti-inflammatory
Technical field
The present invention relates to wash shield product technical field more particularly to a kind of Essence combination applied to head antiallergic anti-inflammatory Object and preparation method thereof.
Background technique
As the improvement of people's living standards, more and more consumers start to pay attention to nursing to scalp, hair etc. and The cosmetics of mild comfortable safety, obvious effect are pursued in maintenance.The shampoo main ingredient of the present market mainstream is that laruyl alcohol is poly- The compositions such as ether sodium sulfate and silicone emulsion, cation, it is irritant to scalp or hair quality, it is be easy to cause skin injury, is caused Allergy inflammation.
Summary of the invention
In view of the deficiencies of the prior art, this invention concept customized using private gene, according to different application on human skin bases Because of examining report, skin physiology, dermatopathology, skin situation, season, age, the dimension scientific design of region seven instantly Customize Essence composition, accomplish flesh of more accurately taking care of hair, it is solved the technical issues of be how to solve shampoo bring Sensitization source is to the injury of skin to achieve the effect that antiallergic anti-inflammatory.
In order to solve the above technical problems, the technical solution adopted by the present invention is that a kind of essence applied to head antiallergic anti-inflammatory Liquid composition is made of following components mass percent: Sodium Hyaluronate 0.1%-5%, D-pantothenyl aleohol 0.01%-9%, allantoin 0.01%-2%, Gotu Kola P.E 0.01%-10%, dipotassium glycyrrhizinate 0.01%-8%, purslane extract 0.01%- 15%, Astragalus membranacus root extract 0.03%-26%, pot marigold flower extract 0.1%-18%, german chamomile flower extract 0.05%- 20%, Geranium Essential 0.01%-1.2%, bisabolol 0.05%-2.4%, pentanediol 1%-5%, EDTA-2Na 0.01- 0.1%, surplus is water.
Further, Essence composition further includes polyalcohols, thickener.
Further, the polyalcohol is one of glycerol, butanediol, propylene glycol, pentanediol, hexylene glycol or one kind Above mixing.
Further, the thickener is coconut monoethanolamide, carbomer, hydroxyethyl cellulose, acrylic acid One of copolymer or more than one mixing.
The invention solves another technical problem be to provide the above-mentioned Essence combination applied to the anti-inflammatory of head antiallergic The preparation method of object.
For this purpose, technical solution provided by the invention is a kind of preparation of Essence composition applied to head antiallergic anti-inflammatory Method, comprising the following steps:
(1) water, EDTA-2Na, carbomer, xanthan gum, butanediol, Sodium Hyaluronate, the allantoin in raw material are added to In emulsion pot, 80 degree are heated to, insulated and stirred 15 minutes, obtains mixture.
(2) mixture in emulsion pot is cooled to 45 degrees Celsius, D-pantothenyl aleohol, dipotassium glycyrrhizinate, purslane is added and extracts Object, Astragalus membranacus root extract, pot marigold flower extract, Gotu Kola P.E, german chamomile flower extract, bisabolol, fish pelargonium Essential oil, pentanediol, are uniformly mixing to obtain finished product.
Compared with prior art, the invention has the advantages that:
D-pantothenyl aleohol in composition is also known as dexpanthenol, can promote the metabolism of human body protein, fat, carbohydrate, protection Skin and mucous membrane, prevent and treat small wrinkle, and inflammation, solarization keep skin soft, effectively prevent the coarse phenomenon of skin, reach skin moisturizing The effect of with tissue repair, gives skin gloss.
Gotu Kola P.E main component asiaticosid in composition has facilitation to fibroblasts from hypertrophic scars vigor, Growth can also be promoted to hair, play the role of reparation and releive.
Dipotassium glycyrrhizinate in composition is mainly that glycyrrhizin (glycyrrhizic acid) ingredient of Radix Glycyrrhizae root and stem was suitble to Red and swollen antiphlogistic healing effect is moved back in quick property skin, anti-irritant and oil-control.Can effectively prevent skin it is stimulated when sensitivity inflammation phenomenon. Inflammation caused by counterglow has anti-inflammatory sedation.
Purslane extract in composition has the antibiotic property of wide spectrum, and has antiinflammation, can prevent and treat skin eczema, mistake The skin diseases such as quick property dermatitis, contact dermatitis;There is good oxygen radical removing ability, illustrates that it has apparent oxidation resistant work With;There is good skin moisture-keeping.
Astragalus membranacus root extract derives from the root of Astragalus membranacus, the important activity ingredient Radix Astragali contained in composition Saponin(e can stimulate the proliferation of cortical cell, there is the effect of conditioning skin.
Pot marigold flower extract main active is carotenoid compounds in composition, there is the work of anti-inflammatory, antibacterial With especially preferable to staphylococcus and streptococcic effect, the increasing based on Calendula officinalis extract to epidermal cell and dermal cell The effect of growing, the inhibition to elastase activity enhance skin activity in conjunction with its outstanding antioxidant.
Bisabolol in composition is extracted from spirea, plays the role of anti-inflammatory antibacterial, and the ingredient stability is good, and Skin has good compatibility, reduces scytitis, mitigates acne, prevents dark sore from generating, improve the anti-irritant energy of skin Power repairs the skin for having inflammation injury.
Specific embodiment
A specific embodiment of the invention is further described below with reference to embodiment, but is not to limit of the invention It is fixed.
Embodiment 1
A kind of Essence composition applied to head antiallergic anti-inflammatory, every 100g are made of the following components: water 91.94g, EDTA-2Na0.05g, carbomer 0.3g, xanthan gum 0.2g, butanediol 5g, Sodium Hyaluronate 0.1g, D-pantothenyl aleohol 0.01g, allantois Plain 0.1g, dipotassium glycyrrhizinate 0.01g, purslane extract 0.01g, Gotu Kola P.E 0.01g, Astragalus membranacus root extract 0.03g, pot marigold flower extract 0.1g, german chamomile flower extract 0.05g, bisabolol 0.05g, Geranium Essential 0.01g, penta 2 Alcohol 2.03g.
Embodiment 2
A kind of Essence composition applied to head antiallergic anti-inflammatory, every 100g are made of the following components: water 73.14g, EDTA-2Na0.05g, carbomer 0.3g, xanthan gum 0.2g, butanediol 5g, Sodium Hyaluronate 0.1g, D-pantothenyl aleohol 2g, allantoin 0.1g, dipotassium glycyrrhizinate 1.05g, purslane extract 4g, Gotu Kola P.E 2.4g, Astragalus membranacus root extract 3.64g, gold Small cup flower flower extract 3.11g, german chamomile flower extract 2.2g, bisabolol 0.55g, Geranium Essential 0.13g, pentanediol 2.03g.
Embodiment 3
A kind of Essence composition applied to head antiallergic anti-inflammatory, every 100g are made of the following components: water 0.74g, EDTA-2Na0.05g, carbomer 0.3g, xanthan gum 0.2g, butanediol 5g, Sodium Hyaluronate 2g, D-pantothenyl aleohol 3g, allantoin 1g, Dipotassium glycyrrhizinate 4g, purslane extract 15g, Gotu Kola P.E 10g, Astragalus membranacus root extract 20g, pot marigold are extracted Object 18g, german chamomile flower extract 18g, bisabolol 0.55g, Geranium Essential 0.13g, pentanediol 2.03g.
1 to 3 preparation method of above-described embodiment, is made up of following steps:
(1) water, EDTA-2Na, carbomer, xanthan gum, butanediol, Sodium Hyaluronate, the allantoin in raw material are added to In emulsion pot, 80 degree are heated to, insulated and stirred 15 minutes, obtains mixture.
(2) mixture in emulsion pot is cooled to 45 degrees Celsius, D-pantothenyl aleohol, dipotassium glycyrrhizinate, purslane is added and extracts Object, Astragalus membranacus root extract, pot marigold flower extract, Gotu Kola P.E, german chamomile flower extract, bisabolol, fish pelargonium Essential oil, pentanediol, are uniformly mixing to obtain finished product.
Beneficial effect in order to better illustrate the present invention carries out efficacy assessments experiment:
Experimental method: filtering out at least 10 faces is sensitive skin or the crowd for being in allergy (rubescent, itch) As sensitive skin volunteer, pass through blank control, after composition of the embodiment of the present invention is smeared by face, difference within (18~45 years old) It was tested at the 0th day, the 7th day and the 14th day, surveys its skin ferroheme value, skin moisture content, these indexs are for commenting After valence skin of head barrier function and use product, the repair ability and antiallergic anti-inflammatory activity of skin.
1 skin moisture content of table
As a result: compared with control sides, after sample 2 weeks, the skin of head moisture content of sample side has apparent increase, Illustrate that skin barrier function is fine.
As a result: after use, the skin ferroheme value of sample sets and control group is reduced, and the reduction amount of sample sets is significant Lower than control group.That is the sample sets effect that has good antiallergic anti-inflammatory, can repair skin, allow skin can insular sensitization source Stimulation.
Detailed description is made that embodiments of the present invention in conjunction with the embodiments above, but the present invention be not limited to it is described Embodiment.To those skilled in the art, without departing from the principles and spirit of the present invention, to these realities The mode of applying carries out various change, modification, replacement and variant are still fallen in protection scope of the present invention.

Claims (6)

1. a kind of Essence composition applied to head antiallergic anti-inflammatory, which is characterized in that by following components mass percent system At: Sodium Hyaluronate 0.1%-5%, D-pantothenyl aleohol 0.01%-9%, allantoin 0.01%-2%, Gotu Kola P.E 0.01%- 10%, dipotassium glycyrrhizinate 0.01%-8%, purslane extract 0.01%-15%, Astragalus membranacus root extract 0.03%- 26%, pot marigold flower extract 0.1%-18%, german chamomile flower extract 0.05%-20%, Geranium Essential 0.01%-1.2%, Bisabolol 0.05%-2.4%, pentanediol 1%-5%, EDTA-2Na0.01-0.1%, surplus are water.
2. the Essence composition according to claim 1 applied to the anti-inflammatory of head antiallergic, which is characterized in that further include more First alcohols, thickener.
3. the Essence composition according to claim 2 applied to the anti-inflammatory of head antiallergic, which is characterized in that described polynary Alcohol is one of glycerol, butanediol, propylene glycol, pentanediol, hexylene glycol or more than one mixing.
4. the Essence composition according to claim 2 applied to the anti-inflammatory of head antiallergic, which is characterized in that the thickening Agent is one of coconut monoethanolamide, carbomer, hydroxyethyl cellulose, acrylic copolymer or more than one is mixed It closes.
5. the Essence composition according to claim 1 applied to the anti-inflammatory of head antiallergic, which is characterized in that by with the following group Point mass percent is made: water 73.14%, EDTA-2Na0.05%, carbomer 0.3%, xanthan gum 0.2%, butanediol 5%, Sodium Hyaluronate 0.1%, D-pantothenyl aleohol 2%, allantoin 0.1%, dipotassium glycyrrhizinate 1.05%, purslane extract 4%, centella It is extract 2.4%, Astragalus membranacus root extract 3.64%, pot marigold flower extract 3.11%, german chamomile flower extract 2.2%, red Bisabol 0.55%, Geranium Essential 0.13%, pentanediol 2.03%.
6. a kind of preparation side of such as Essence composition described in any one of claim 1 to 5 applied to the anti-inflammatory of head antiallergic Method, which comprises the following steps:
(1) water, EDTA-2Na, carbomer, xanthan gum, butanediol, Sodium Hyaluronate, the allantoin in raw material are added to emulsification In pot, 80 degree are heated to, insulated and stirred 15 minutes, obtains mixture.
(2) mixture in emulsion pot is cooled to 45 degrees Celsius, D-pantothenyl aleohol, dipotassium glycyrrhizinate, purslane extract, film is added Pod Radix Astragali root extract, pot marigold flower extract, Gotu Kola P.E, german chamomile flower extract, bisabolol, Geranium Essential, Pentanediol is uniformly mixing to obtain finished product.
CN201910315086.XA 2019-04-18 2019-04-18 A kind of Essence composition and preparation method thereof applied to head antiallergic anti-inflammatory Withdrawn CN110051577A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327265A (en) * 2019-08-09 2019-10-15 广州环亚化妆品科技有限公司 Scalp care composition and preparation method and application thereof
CN111671697A (en) * 2020-07-28 2020-09-18 广州宏众生物科技有限公司 Plant anti-allergy liquid and application thereof in cosmetics
CN113069389A (en) * 2020-01-06 2021-07-06 广州樱奈儿化妆品有限公司 Liquorice anti-allergy repair essence and preparation method thereof
CN114515261A (en) * 2022-01-11 2022-05-20 仲恺农业工程学院 Conditioning essence for men and preparation method thereof
CN115252517A (en) * 2022-07-26 2022-11-01 广州陶妆生物科技有限公司 Red-fading anti-inflammation essence

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327265A (en) * 2019-08-09 2019-10-15 广州环亚化妆品科技有限公司 Scalp care composition and preparation method and application thereof
CN113069389A (en) * 2020-01-06 2021-07-06 广州樱奈儿化妆品有限公司 Liquorice anti-allergy repair essence and preparation method thereof
CN111671697A (en) * 2020-07-28 2020-09-18 广州宏众生物科技有限公司 Plant anti-allergy liquid and application thereof in cosmetics
CN111671697B (en) * 2020-07-28 2020-12-25 广州宏众生物科技有限公司 Plant anti-allergy liquid and application thereof in cosmetics
CN114515261A (en) * 2022-01-11 2022-05-20 仲恺农业工程学院 Conditioning essence for men and preparation method thereof
CN114515261B (en) * 2022-01-11 2023-05-05 仲恺农业工程学院 Male conditioning essence and preparation method thereof
CN115252517A (en) * 2022-07-26 2022-11-01 广州陶妆生物科技有限公司 Red-fading anti-inflammation essence

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