CN112675094A - Plant extract, repairing composition, skin care product and preparation method thereof - Google Patents

Plant extract, repairing composition, skin care product and preparation method thereof Download PDF

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CN112675094A
CN112675094A CN202110038234.5A CN202110038234A CN112675094A CN 112675094 A CN112675094 A CN 112675094A CN 202110038234 A CN202110038234 A CN 202110038234A CN 112675094 A CN112675094 A CN 112675094A
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parts
extract
weight
care product
skin care
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曹崇江
婺伸
程抒劼
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China Pharmaceutical University
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China Pharmaceutical University
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Abstract

The invention discloses a plant extract, a repair composition, a skin care product and a preparation method thereof, wherein the plant extract comprises a purslane extract, a ginseng root extract, a scutellaria root extract, a angelica root extract and a sea buckthorn extract, the repair composition comprises the plant extract, a poria peel extract, palmitoyl tripeptide-8 and copper peptide, the skin care product can be prepared by adding an auxiliary agent into the repair composition, the skin care product can synergistically play a skin repair role on different levels of cells, tissues and the like, and also has multiple effects of resisting inflammation, resisting allergy, delaying skin aging, improving skin color and the like.

Description

Plant extract, repairing composition, skin care product and preparation method thereof
Technical Field
The invention relates to a plant extract, a repairing composition, a skin care product and a preparation method thereof, in particular to a plant extract, a repairing composition, a skin care product and a preparation method thereof with a synergistic repairing effect.
Background
With the continuous development of society and the continuous improvement of living standard of people, people pay more and more attention to the skin care. However, the skin suffers from damage from ultraviolet rays and radiation on the one hand, and also suffers from adverse effects due to life stress and improper eating habits on the other hand. In the face of faster and faster pace of life, people need a skin care product which is convenient to carry, quick to use and high in cost performance, and the facial mask meeting the requirements naturally becomes a skin care product variety which is more and more favored by people. When the facial mask is used, the skin temperature can be increased, the skin can be promoted to expand, various pollutants in pores can be cleaned, and the functional components contained in the facial mask can be tightly attached to the skin, so that the skin can better absorb moisture and nutrients in the pores, and the skin is soft, smooth and elastic. At present, the facial masks on the market are various in types and are mixed with fish eyes, so that in order to meet the requirements of people on high-quality facial masks, a safe, effective and non-irritant repairing facial mask needs to be developed.
Disclosure of Invention
The purpose of the invention is as follows: the invention has the first purpose of providing a plant extract, the second purpose of providing a repair composition containing the plant extract, the third purpose of providing a skin care product containing the repair composition, and the fourth purpose of providing a preparation method of the skin care product.
The technical scheme is as follows: the plant extracts of the present invention comprise purslane extract, ginseng root extract, scutellaria root extract, angelica root extract and hippophae rhamnoides extract.
Further, the plant extract comprises, by weight, 0.3-2 parts of purslane extract, 0.3-2 parts of ginseng root extract, 0.3-2 parts of scutellaria root extract, 0.3-2 parts of angelica root extract and 0.3-2 parts of sea buckthorn extract.
The repair composition comprises the plant composition, poria peel extract, palmitoyl tripeptide-8 and copper peptide.
Further, the repairing composition comprises 1.5-7.5 parts of the plant composition, 1-5 parts of poria peel extract, 80.5-4 parts of palmitoyl tripeptide and 0.5-4 parts of copper peptide in parts by weight; further, the composition comprises 2.5-7.5 parts of the plant composition, 1-4 parts of poria peel extract, 81-3 parts of palmitoyl tripeptide and 1-3 parts of copper peptide; most preferably, the composition comprises 2.5-5 parts of the plant composition, 2-4 parts of poria peel extract, 82-3 parts of palmitoyl tripeptide and 2-3 parts of copper peptide.
Wherein, the main components of the poria peel extract comprise triterpenes and sterols, and the poria peel extract has the effects of resisting inflammation, controlling oil, eliminating free radicals, resisting oxidation, efficiently preserving moisture and the like. The extract of the poria peel can also increase the production of collagen, fill and repair damaged and aged skin, and enhance the expansive force of damaged skin.
The herba Portulacae extract contains flavone and saponin, and has effects of scavenging free radicals and resisting oxidation, and can be used for delaying skin aging. Experimental research shows that the purslane extract has obvious itching relieving function and obvious inhibition effect on pain and red swelling.
The ginseng root extract is rich in eighteen ginsenoside monomer, can promote blood circulation, prevent skin aging and wrinkle generation, increase the nutrition supply of the skin, improve the immunity, prevent the skin from being harmfully stimulated by the outside, and has obvious effects on removing spots, delaying aging, activating skin cells and enhancing the skin elasticity.
The radix Scutellariae extract contains baicalin as main ingredient. It has effects in inhibiting various skin pathogenic fungi, resisting inflammation, and resisting allergy. In addition, baicalin zinc and baicalin copper in the scutellaria baicalensis extract have obvious scavenging effect on superoxide radical, and protect skin cells from being excessively oxidized by the superoxide radical.
Main active ingredients of the angelica root extract comprise ferulic acid, nicotinic acid, various amino acids, saponin, flavone, polysaccharide and the like. The angelica extract has good SOD-like activity, and has special effects of inhibiting membrane lipid peroxidation and free radical reaction caused by superoxide radical, and resisting dark complexion caused by free radical retardation.
The sea buckthorn extract is rich in a plurality of active substances such as vitamin A, vitamin E, flavone and the like, can effectively help skin to resist oxidation and reduce the harm of free radicals, and in addition, the sea buckthorn extract contains a fruit element component, can be directed against propionibacterium acnes, can inhibit the infection of the propionibacterium acnes, and has excellent effects of removing acnes and marks and repairing damaged skin.
The palmitoyl tripeptide-8 has the performance of promoting the synthesis of collagen and elastin in a dermis layer, is an ideal raw material for accelerating the generation of the collagen and repairing wrinkles, and has the characteristics of enhancing cell activity, preventing the growth of human fiber cells, repairing aged human cells, increasing the moisture content of skin, enhancing the luster of the skin and improving the skin color.
The copper peptide is a signal peptide and a carrier peptide, is used for stabilizing and transporting copper, can promote the generation of normal collagen, elastin, proteoglycan and glucosaminan of the skin, and can repair and reshape the skin. The Cu ions exert a signaling function that can affect cell behavior and metabolism, e.g., enough Cu ions are a signal for stem cell proliferation and tissue repair.
The tuckahoe has remarkable effects on the aspects of skin repair, maintenance, whitening and the like. The purslane, ginseng and other plants have the effects of resisting bacteria, improving skin color and the like, and the effects of the poria peel can be supplemented by compounding the purslane, ginseng and other plants, so that the synergistic repairing effect is achieved. The small molecular peptide has the effects of inhibiting cytopathic effect, repairing damaged cells and promoting cell metabolism. The poria peel extract and the small molecular peptide are used as main functional components, so that the skin care product has small irritation to the skin, and also has multiple effects of moisturizing, resisting bacteria, resisting inflammation, resisting allergy, delaying skin aging, improving skin color and the like.
The skin care article of the present application comprises the above-described repair composition and an adjuvant. Wherein the auxiliary agent comprises carbomer, hydroxyethyl cellulose, scleroglucan, sodium hyaluronate, p-hydroxyacetophenone, trehalose, betaine, glycerol, 1, 2-butanediol, ethylhexyl glycerol, 1, 2-hexanediol, triethanolamine and water.
Furthermore, the skin care product contains 0.1-0.2 part of carbomer, 0.05-0.12 part of hydroxyethyl cellulose, 0.05-0.15 part of sclerotium rolfsii gum, 0.03-0.15 part of sodium hyaluronate, 0.4-0.6 part of p-hydroxyacetophenone, 0.6-1.5 parts of trehalose, 0.6-1.5 parts of betaine, 3-6 parts of glycerol, 3-6 parts of 1, 2-butanediol, 0.06-0.2 part of ethylhexylglycerol, 0.4-0.6 part of 1, 2-hexanediol, 0.1-0.2 part of triethanolamine and 60-90 parts of water in parts by weight; further, the disinfectant comprises 0.12-0.16 part of carbomer, 0.06-0.1 part of hydroxyethyl cellulose, 0.06-0.1 part of sclerotium rolfsii gum, 0.04-0.1 part of sodium hyaluronate, 0.45-0.55 part of p-hydroxyacetophenone, 0.8-1.2 parts of trehalose, 0.8-1.2 parts of betaine, 3-5 parts of glycerol, 3-5 parts of 1, 2-butanediol, 0.08-0.15 part of ethylhexylglycerol, 0.45-0.55 part of 1, 2-hexanediol, 0.12-0.16 part of triethanolamine and 65-85 parts of water; most preferably, the water-soluble organic solvent-based cleaning agent comprises 0.12-0.16 part of carbomer, 0.08-0.1 part of hydroxyethyl cellulose, 0.06-0.1 part of sclerotium rolfsii gum, 0.05-0.1 part of sodium hyaluronate, 0.5-0.55 part of p-hydroxyacetophenone, 1-1.2 parts of trehalose, 1-1.2 parts of betaine, 3-5 parts of glycerol, 3-5 parts of 1, 2-butanediol, 0.1-0.15 part of ethylhexylglycerol, 0.5-0.55 part of 1, 2-hexanediol, 0.12-0.16 part of triethanolamine and 70-85 parts of water.
The preparation method of the skin care product comprises the following steps:
(1) preparing plant extract and Poria peel extract;
the plant extract concrete method comprises the following steps:
extracting purslane powder with 70-75% ethanol under reflux at 80-85 ℃ for 2-3 h. The reflux extraction is repeated for 2-3 times, and the ratio of the material to the liquid is 1: 8-1: 12 (W: V). Concentrating and drying the purslane ethanol extract to obtain the purslane extract.
Extracting the ginseng powder by 60 to 70 percent ethanol for 3 to 4 hours under the condition of 80 to 85 ℃. The reflux extraction is repeated for 2-3 times, and the ratio of the material to the liquid is 1: 15-1: 20 (W: V). Concentrating and drying the ginseng ethanol extract to obtain the ginseng extract.
Extracting the scutellaria baicalensis powder by using 75 to 85 percent ethanol under reflux for 1.5 to 2 hours at the temperature of between 80 and 85 ℃. The reflux extraction is repeated for 2-3 times, and the ratio of the material to the liquid is 1: 12-1: 15 (W: V). Concentrating and drying the ethanol extract of the scutellaria to obtain the scutellaria extract.
Extracting angelica powder with 70-80% ethanol at 80-85 deg.c for 3-4 hr. The reflux extraction is repeated for 2-3 times, and the ratio of the material to the liquid is 1: 12-1: 15 (W: V). Concentrating and drying the angelica ethanol extract to obtain the angelica extract.
The sea-buckthorn powder is extracted by 60 to 70 percent ethanol under reflux for 1.5 to 2 hours at the temperature of between 80 and 85 ℃. The reflux extraction is repeated for 2-3 times, and the ratio of the material to the liquid is 1: 8-1: 12 (W: V). Concentrating and drying the ethanol extract of seabuckthorn to obtain the seabuckthorn extract.
The specific method of the poria peel extract comprises the following steps:
extracting the poria peel powder with 85-95% ethanol at 80-85 ℃ for 1.5-2 h under reflux. The reflux extraction is repeated for 2-3 times, and the ratio of the material to the liquid is 1: 8-1: 12 (W: V). And carrying out suction filtration on the extraction mixture for 2-3 times to obtain clear filtrate. And rotatably evaporating the filtrate at the temperature of 60-65 ℃ to obtain an extract. And (4) putting the extract into a tray, drying and grinding to obtain the poria peel extract.
(2) Preparing a first mixture: adding carbomer, sclerotium rolfsii gum, hydroxyethyl cellulose, sodium hyaluronate and p-hydroxyacetophenone into water, heating, and stirring by using a homogenizer until the carbomer, the sclerotium rolfsii gum, the hydroxyethyl cellulose, the sodium hyaluronate and the p-hydroxyacetophenone are completely dissolved to obtain a first mixture, wherein the heating and dissolving temperature is 70-75 ℃;
(3) preparation of a second mixture: cooling the mixture I prepared in the step (2), adding trehalose, betaine, glycerol, 1, 2-butanediol and ethylhexylglycerin, and continuously stirring until the trehalose, the betaine, the glycerol, the 1, 2-butanediol and the ethylhexylglycerin are completely dissolved to obtain a mixture II, wherein the temperature for cooling and dissolving is 60-65 ℃;
(4) preparing a skin care product: and (3) cooling the mixture II prepared in the step (3), adding the poria peel extract, the plant extract, the palmitoyl tripeptide-8, the copper peptide and the 1, 2-hexanediol, continuously stirring until the mixture is completely dissolved, uniformly mixing, and adding triethanolamine to obtain the skin care product, wherein the temperature for cooling and dissolving is 50-55 ℃.
The skin care product can be used alone or adsorbed on carrier material.
Has the advantages that: compared with the prior art, the invention has the following remarkable advantages:
(1) the components play a synergistic role, make up the functional defects of a single component, enable the skin care product to play a skin repairing role in a synergistic way on different levels of cells, tissues and the like, and simultaneously have multiple effects of resisting inflammation, resisting allergy, delaying skin aging, improving skin color and the like;
(2) the adopted main raw materials are extracted and prepared from natural plants, have no toxic or side effect and drug dependence, and are suitable for audiences of people of all ages;
(3) the extraction method of each extract is convenient and efficient to operate, and can effectively extract active substances in medicinal materials.
Detailed Description
The technical solution of the present invention is further illustrated by the following examples.
Example 1
The skin care product comprises the following raw material components in parts by weight: 3 parts of poria peel extract, 5 parts of plant extract, 82 parts of palmitoyl tripeptide, 2 parts of copper peptide, 0.12 part of carbomer, 0.08 part of sclerotium rolfsii gum, 0.08 part of hydroxyethyl cellulose, 0.05 part of sodium hyaluronate, 0.5 part of p-hydroxyacetophenone, 1 part of trehalose, 1 part of betaine, 4 parts of glycerol, 4 parts of 1, 2-butanediol, 0.1 part of ethylhexylglycerol, 0.5 part of 1, 2-hexanediol, 0.12 part of triethanolamine and 70 parts of deionized water. The plant extract comprises the following raw material components in parts by weight: 1 part of purslane extract, 1 part of ginseng root extract, 1 part of scutellaria root extract, 1 part of angelica root extract and 1 part of sea buckthorn extract.
The preparation method of the skin care product comprises the following steps:
1. accurately weighing poria peel powder, and extracting with 95% ethanol at 80 deg.C under reflux for 2 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 8 (W: V). The extract mixture was suction filtered 2 times to obtain a clear filtrate. And rotatably evaporating the filtrate at 60 ℃ to obtain an extract. And (4) putting the extract into a tray, drying and grinding to obtain the poria peel extract.
Extracting herba Portulacae powder with 70% ethanol at 80 deg.C under reflux for 2 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 8 (W: V). Concentrating and drying the purslane ethanol extract to obtain the purslane extract.
Extracting Ginseng radix powder with 60% ethanol at 80 deg.C under reflux for 3 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 15 (W: V). Concentrating and drying the ginseng ethanol extract to obtain the ginseng extract.
Extracting Scutellariae radix powder with 75% ethanol at 80 deg.C under reflux for 1.5 h. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 12 (W: V). Concentrating and drying the ethanol extract of the scutellaria to obtain the scutellaria extract.
Extracting radix Angelicae sinensis powder with 70% ethanol at 80 deg.C under reflux for 3 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 12 (W: V). Concentrating and drying the angelica ethanol extract to obtain the angelica extract.
Extracting fructus Hippophae powder with 60% ethanol at 80 deg.C under reflux for 1.5. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 8 (W: V). Concentrating and drying the ethanol extract of seabuckthorn to obtain the seabuckthorn extract.
2. Weighing the components according to the formula of the skin care product for later use;
3. adding carbomer, sclerotium rolfsii gum, hydroxyethyl cellulose, sodium hyaluronate and p-hydroxyacetophenone into deionized water, heating to 70 ℃, and stirring by a homogenizer until the carbomer, the sclerotium rolfsii gum, the hydroxyethyl cellulose, the sodium hyaluronate and the p-hydroxyacetophenone are completely dissolved to obtain a transparent mixture I with uniform homogenization and dispersion.
4. And (3) cooling the mixture I, keeping the temperature at 60 ℃, taking trehalose, betaine, glycerol, 1, 2-butanediol and ethylhexyl glycerol, and continuously stirring until the trehalose, the betaine, the glycerol, the 1, 2-butanediol and the ethylhexyl glycerol are completely dissolved. Obtaining a second transparent mixture which is evenly dispersed.
5. Cooling the mixture II, maintaining the temperature at 55 deg.C, adding plant extract, palmitoyl tripeptide-8, copper peptide, and 1, 2-hexanediol, and stirring to dissolve completely. And adding triethanolamine after uniformly mixing to obtain the skin care product.
Example 2
The skin care product comprises the following raw material components in parts by weight: 5 parts of poria peel extract, 7.5 parts of plant extract, 84 parts of palmitoyl tripeptide, 4 parts of copper peptide, 0.2 part of carbomer, 0.15 part of sclerotium rolfsii gum, 0.12 part of hydroxyethyl cellulose, 0.15 part of sodium hyaluronate, 0.6 part of p-hydroxyacetophenone, 1.5 parts of trehalose, 1.5 parts of betaine, 6 parts of glycerol, 6 parts of 1, 2-butanediol, 0.2 part of ethylhexyl glycerol, 0.6 part of 1, 2-hexanediol, 0.2 part of triethanolamine and 60 parts of deionized water. The plant extract comprises the following raw material components in parts by weight: 2 parts of purslane extract, 2 parts of ginseng root extract, 2 parts of scutellaria root extract, 2 parts of angelica root extract and 2 parts of sea buckthorn extract.
The preparation method of the skin care product comprises the following steps:
1. accurately weighing Poria peel powder, and extracting with 90% ethanol at 85 deg.C under reflux for 1.5 h. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 8 (W: V). The extract mixture was suction filtered twice to obtain a clear filtrate. And rotatably evaporating the filtrate at 60 ℃ to obtain an extract. And (4) putting the extract into a tray, drying and grinding to obtain the poria peel extract.
Extracting herba Portulacae powder with 75% ethanol at 85 deg.C under reflux for 3 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 12 (W: V). Concentrating and drying the purslane ethanol extract to obtain the purslane extract.
Extracting Ginseng radix powder with 65% ethanol at 85 deg.C under reflux for 4 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 20 (W: V). Concentrating and drying the ginseng ethanol extract to obtain the ginseng extract.
Extracting Scutellariae radix powder with 80% ethanol at 85 deg.C under reflux for 2 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 15 (W: V). Concentrating and drying the ethanol extract of the scutellaria to obtain the scutellaria extract.
Extracting radix Angelicae sinensis powder with 75% ethanol at 85 deg.C under reflux for 4 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 15 (W: V). Concentrating and drying the angelica ethanol extract to obtain the angelica extract.
Extracting fructus Hippophae powder with 65% ethanol at 85 deg.C under reflux for 2 hr. Reflux extraction was repeated 3 times with a feed-to-liquid ratio of 1: 12 (W: V). Concentrating and drying the ethanol extract of seabuckthorn to obtain the seabuckthorn extract.
2. Weighing the components according to the formula of the skin care product for later use;
3. adding carbomer, sclerotium rolfsii gum, hydroxyethyl cellulose, sodium hyaluronate and p-hydroxyacetophenone into deionized water, heating to 75 ℃, and stirring by using a homogenizer until the carbomer, the sclerotium rolfsii gum, the hydroxyethyl cellulose, the sodium hyaluronate and the p-hydroxyacetophenone are completely dissolved to obtain a transparent mixture I which is uniformly homogenized and dispersed.
4. And cooling the mixture I, keeping the temperature at 65 ℃, taking trehalose, betaine, glycerol, 1, 2-butanediol and ethylhexyl glycerol, and continuously stirring until the trehalose, the betaine, the glycerol, the 1, 2-butanediol and the ethylhexyl glycerol are completely dissolved. Obtaining a second transparent mixture which is evenly dispersed.
5. Cooling the mixture II, keeping the temperature at 50 ℃, adding the plant extract, the palmitoyl tripeptide-8, the copper peptide and the 1, 2-hexanediol, and continuously stirring until the mixture is completely dissolved. And adding triethanolamine after uniformly mixing to obtain the skin care product.
Example 3
The repairing mask comprises the following raw material components in parts by weight: 1 part of poria peel extract, 1.5 parts of plant extract, 80.5 parts of palmitoyl tripeptide, 0.5 part of copper peptide, 0.1 part of carbomer, 0.05 part of sclerotium rolfsii gum, 0.05 part of hydroxyethyl cellulose, 0.03 part of sodium hyaluronate, 0.4 part of p-hydroxyacetophenone, 0.6 part of trehalose, 0.6 part of betaine, 3 parts of glycerol, 3 parts of 1, 2-butanediol, 0.06 part of ethylhexyl glycerol, 0.4 part of 1, 2-hexanediol, 0.1 part of triethanolamine and 90 parts of deionized water. The plant extract comprises the following raw material components in parts by weight: 0.3 part of purslane extract, 0.3 part of ginseng root extract, 0.3 part of scutellaria root extract, 0.3 part of angelica root extract and 0.3 part of sea buckthorn extract.
The preparation method of the skin care product comprises the following steps:
1. accurately weighing Poria peel powder, and extracting with 85% ethanol at 85 deg.C under reflux for 1.5 h. Reflux extraction was repeated 2 times with a feed-to-liquid ratio of 1: 12 (W: V). The extract mixture was suction filtered twice to obtain a clear filtrate. And rotatably evaporating the filtrate at 65 ℃ to obtain an extract. And (4) putting the extract into a tray, drying and grinding to obtain the poria peel extract.
Extracting herba Portulacae powder with 75% ethanol at 85 deg.C under reflux for 3 hr. Reflux extraction was repeated 2 times with a feed-to-liquid ratio of 1: 12 (W: V). Concentrating and drying the purslane ethanol extract to obtain the purslane extract.
Extracting Ginseng radix powder with 70% ethanol at 85 deg.C under reflux for 4 hr. Reflux extraction was repeated 2 times with a feed-to-liquid ratio of 1: 20 (W: V). Concentrating and drying the ginseng ethanol extract to obtain the ginseng extract.
Extracting Scutellariae radix powder with 85% ethanol at 85 deg.C under reflux for 2 hr. Reflux extraction was repeated 2 times with a feed-to-liquid ratio of 1: 15 (W: V). Concentrating and drying the ethanol extract of the scutellaria to obtain the scutellaria extract.
Extracting radix Angelicae sinensis powder with 80% ethanol at 85 deg.C under reflux for 4 hr. Reflux extraction was repeated 2 times with a feed-to-liquid ratio of 1: 15 (W: V). Concentrating and drying the angelica ethanol extract to obtain the angelica extract.
Extracting fructus Hippophae powder with 70% ethanol at 85 deg.C under reflux for 2 hr. Reflux extraction was repeated 2 times with a feed-to-liquid ratio of 1: 12 (W: V). Concentrating and drying the ethanol extract of seabuckthorn to obtain the seabuckthorn extract.
2. Weighing the components according to the formula of the skin care product for later use;
3. adding carbomer, sclerotium rolfsii gum, hydroxyethyl cellulose, sodium hyaluronate and p-hydroxyacetophenone into deionized water, heating to 70 ℃, and stirring by a homogenizer until the carbomer, the sclerotium rolfsii gum, the hydroxyethyl cellulose, the sodium hyaluronate and the p-hydroxyacetophenone are completely dissolved to obtain a transparent mixture I with uniform homogenization and dispersion.
4. And (3) cooling the mixture I, keeping the temperature at 60 ℃, taking trehalose, betaine, glycerol, 1, 2-butanediol and ethylhexyl glycerol, and continuously stirring until the trehalose, the betaine, the glycerol, the 1, 2-butanediol and the ethylhexyl glycerol are completely dissolved. Obtaining a second transparent mixture which is evenly dispersed.
5. Cooling the mixture II, maintaining the temperature at 55 deg.C, adding plant extract, palmitoyl tripeptide-8, copper peptide, and 1, 2-hexanediol, and stirring to dissolve completely. And adding triethanolamine after uniformly mixing to obtain the skin care product.
Example 4
The difference from example 1 is that:
the repairing mask comprises the following raw material components in parts by weight: 2 parts of poria peel extract, 2.5 parts of plant extract, 83 parts of palmitoyl tripeptide, 1 part of copper peptide, 0.16 part of carbomer, 0.06 part of sclerotium rolfsii gum, 0.06 part of hydroxyethyl cellulose, 0.1 part of sodium hyaluronate, 0.45 part of p-hydroxyacetophenone, 0.8 part of trehalose, 0.8 part of betaine, 5 parts of glycerol, 5 parts of 1, 2-butanediol, 0.08 part of ethylhexyl glycerol, 0.45 part of 1, 2-hexanediol, 0.16 part of triethanolamine and 65 parts of deionized water. The plant extract comprises the following raw material components in parts by weight: 1.5 parts of purslane extract, 1.5 parts of ginseng root extract, 1.5 parts of scutellaria root extract, 1.5 parts of angelica root extract and 1.5 parts of sea buckthorn extract.
Example 5
The difference from example 1 is that:
the repairing mask comprises the following raw material components in parts by weight: 4 parts of poria peel extract, 5 parts of plant extract, 81 parts of palmitoyl tripeptide, 3 parts of copper peptide, 0.1 part of carbomer, 0.1 part of sclerotium rolfsii gum, 0.1 part of hydroxyethyl cellulose, 0.04 part of sodium hyaluronate, 0.55 part of p-hydroxyacetophenone, 1.2 parts of trehalose, 1.2 parts of betaine, 5 parts of glycerol, 5 parts of 1, 2-butanediol, 0.15 part of ethylhexyl glycerol, 0.55 part of 1, 2-hexanediol, 0.16 part of triethanolamine and 85 parts of deionized water. The plant extract comprises the following raw material components in parts by weight: 1 part of purslane extract, 1 part of ginseng root extract, 1 part of scutellaria root extract, 1 part of angelica root extract and 1 part of sea buckthorn extract.
Comparative example 1
The difference from example 1 is that:
the skin care product formula does not contain plant extract, poria peel extract, palmitoyl tripeptide-8 and copper peptide.
Comparative example 2
The difference from example 1 is that:
(1) in the formula of the plant extract, the components are respectively 0.05 part by weight;
(2) in the formula of the skin care product, by weight, the plant extract is 0.05 part, the poria peel extract is 0.5 part, the palmitoyl tripeptide-8 is 10 parts, and the copper peptide is 10 parts.
Example 6: capability of repairing skin damage caused by ultraviolet irradiation
30 SPF-grade female mice were randomly divided into 5 groups of 6 mice, wherein 1 group was a blank group and 4 groups were test groups (model group, example 1 group, comparative example 2 group). The hairs on the backs of the mice were removed by a razor, and during the experiment, the mice in the test group were irradiated with UVB (312nm) for 2 hours under an ultraviolet lamp every 2 days, and then 100 μ l of the corresponding skin care products were applied to the bare back skins of the mice in the example 1 group, the comparative example 1 group, and the comparative example 2 group every day.
3. Results of the experiment
On the fifth day, the mice in the model group, comparative example 1 group and comparative example 2 began to develop large-scale erythema, rough chapping, and decreased elasticity, but example 1 was relatively mild, with a smaller range of erythema, and a lower degree of chapping.
On day seven, the bare skin of the model group, comparative example 1 group and comparative example 2 group had almost scabs, the scab range of the example 1 group was small, and local regrowth of hairs in the bare skin began.
On the ninth day, 2 mice in the group of example 1 had complete callus detachment, and the other 3 groups had continued to begin callus detachment.
On the fourteenth day, only 1 small wound after escharosis remained in the group of example 1, 3 eschar were completely removed in the group of comparative example 2, 2 eschar were completely removed in the group of comparative example 1, and 1 eschar was completely removed in the model group.
On the nineteenth day, the wounds of the model group, the comparative example 1 group and the comparative example 2 group healed, but the mouse had a red stripe area in the middle of the bare skin, and the skin had a thicker hand feeling, was rougher and lacked elasticity with different wrinkles around the mouse. The skin of the group of example 1 recovered better, the bare skin was already covered with a new layer of hair, and the skin felt was more elastic.
From the above experimental results, compared with the skin care product group using comparative examples 1 to 2 and the skin care product group not using, the skin care product of example 1 has faster repair to the skin when the skin is damaged by ultraviolet rays, and has better repair effect because the skin is more elastic after being repaired, which shows that the botanical composition, the repair composition and the skin care product of the present application are obtained by screening and optimizing.
Example 7: repair ability to skin damage caused by inflammation
12 female mice of SPF grade were taken, 6 of which had a blank group on the left ear and a model group on the right ear, and 6 of which had a group of example 1 on the left ear and a group of comparative example 1 on the right ear. The model group, the example 1 group and the comparative example 1 group were applied with 10mg/ml oxazolone 50 μ l each day, and after half an hour, the skin care products corresponding to the example 1 group and the comparative example 1 group were administered with 50 μ l.
On day eight, the degree of ear repair was evaluated based on the degree of erythema, thickening and weight gain of the ear. The degree of erythema is divided into none, 0 points; mild, 1 point; medium, 2 points; severe, 3 points. The thickness was measured by a vernier caliper and the degree of thickening was compared with a blank set of 1. The weight was measured on a balance, the degree of weight gain was compared with that of the blank group of 1, and the evaluation results are shown in Table 1.
TABLE 1 ability to repair skin damage caused by inflammation
Figure BDA0002894196800000081
As can be seen from table 1, the skin care product of experimental example 1 has good anti-inflammatory activity in skin and better repairing effect on skin compared to the skin care product group of comparative example 1 and the skin care product group without skin, which indicates that the botanical composition, the repairing composition and the skin care product of the present application are obtained by screening and optimizing.

Claims (10)

1. A plant extract comprising a purslane extract, a ginseng root extract, a scutellaria root extract, a angelica root extract and a sea buckthorn extract.
2. The plant extract according to claim 1, wherein the plant extract comprises 0.3-2 parts by weight of purslane extract, 0.3-2 parts by weight of ginseng root extract, 0.3-2 parts by weight of scutellaria root extract, 0.3-2 parts by weight of angelica root extract and 0.3-2 parts by weight of sea buckthorn extract.
3. A restorative composition comprising the botanical composition of claim 1 or 2, poria peel extract, palmitoyl tripeptide-8, and copper peptide.
4. The repair composition according to claim 3, wherein the repair composition comprises 1.5 to 7.5 parts by weight of the botanical composition of claim 1 or 2, 1 to 5 parts by weight of a poria peel extract, 80.5 to 4 parts by weight of palmitoyl tripeptide, and 0.5 to 4 parts by weight of copper peptide.
5. The repair composition according to claim 4, wherein the repair composition comprises 2.5 to 7.5 parts by weight of the plant composition of claim 1 or 2, 1 to 4 parts by weight of a poria peel extract, 81 to 3 parts by weight of palmitoyl tripeptide, and 1 to 3 parts by weight of copper peptide.
6. The repair composition according to claim 5, wherein the repair composition comprises 2.5 to 5 parts by weight of the plant composition of claim 1 or 2, 2 to 4 parts by weight of a poria peel extract, 82 to 3 parts by weight of palmitoyl tripeptide, and 2 to 3 parts by weight of copper peptide.
7. A skin care product comprising the repair composition of any one of claims 3 to 6 and an auxiliary agent.
8. The skin care product of claim 7 wherein the adjuvants comprise carbomer, hydroxyethyl cellulose, scleroglucan, sodium hyaluronate, p-hydroxyacetophenone, trehalose, betaine, glycerol, 1, 2-butanediol, ethylhexylglycerin, 1, 2-hexanediol, triethanolamine, and water.
9. The skin care product of claim 8, wherein the auxiliary agent comprises, by weight, 0.1 to 0.2 parts of carbomer, 0.05 to 0.12 parts of hydroxyethyl cellulose, 0.05 to 0.15 parts of sclerotium rolfsii gum, 0.03 to 0.15 parts of sodium hyaluronate, 0.4 to 0.6 parts of p-hydroxyacetophenone, 0.6 to 1.5 parts of trehalose, 0.6 to 1.5 parts of betaine, 3 to 6 parts of glycerol, 3 to 6 parts of 1, 2-butanediol, 0.06 to 0.2 parts of ethylhexylglycerin, 0.4 to 0.6 parts of 1, 2-hexanediol, 0.1 to 0.2 parts of triethanolamine, and 60 to 90 parts of water.
10. A method for preparing a skin care product according to any one of claims 7 to 9, wherein the method comprises the following steps:
(1) preparing plant extract and Poria peel extract;
(2) preparing a first mixture: adding carbomer, sclerotium rolfsii gum, hydroxyethyl cellulose, sodium hyaluronate and p-hydroxyacetophenone into water, heating, and stirring by a homogenizer until the carbomer, the sclerotium rolfsii gum, the hydroxyethyl cellulose, the sodium hyaluronate and the p-hydroxyacetophenone are completely dissolved to obtain a first mixture;
(3) preparation of a second mixture: cooling the mixture I prepared in the step (2), adding trehalose, betaine, glycerol, 1, 2-butanediol and ethylhexylglycerin, and continuously stirring until the trehalose, the betaine, the glycerol, the 1, 2-butanediol and the ethylhexylglycerin are completely dissolved to obtain a mixture II;
(4) preparing a skin care product: and (4) cooling the mixture II prepared in the step (3), adding the poria peel extract, the plant extract, the palmitoyl tripeptide-8, the copper peptide and the 1, 2-hexanediol, continuously stirring until the mixture is completely dissolved, uniformly mixing, and adding triethanolamine to obtain the skin care product.
CN202110038234.5A 2021-01-12 2021-01-12 Plant extract, repairing composition, skin care product and preparation method thereof Pending CN112675094A (en)

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