CN108272665A - A kind of weak acid acidic amino acid skin-clean cream and preparation method thereof - Google Patents
A kind of weak acid acidic amino acid skin-clean cream and preparation method thereof Download PDFInfo
- Publication number
- CN108272665A CN108272665A CN201810346177.5A CN201810346177A CN108272665A CN 108272665 A CN108272665 A CN 108272665A CN 201810346177 A CN201810346177 A CN 201810346177A CN 108272665 A CN108272665 A CN 108272665A
- Authority
- CN
- China
- Prior art keywords
- skin
- phases
- amino acid
- acidic amino
- clean cream
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/817—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Compositions or derivatives of such polymers, e.g. vinylimidazol, vinylcaprolactame, allylamines (Polyquaternium 6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/007—Preparations for dry skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to a kind of weak acid acidic amino acid skin-clean creams and preparation method thereof, and the skin-clean cream is grouped as by the group of following mass percents：Sodium lauroyl glutamate 20.0~25.0%, cocounut oil acyl isethionic acid ester sodium 5.0~7.0%, cocoamido sodium propionate 1.5~2.5%, polyquaternium 51 0.5~2.0%, starfish branch tube algae extract 1.0~5.0%, butanediol 15.0~18.0%, methyl propanediol 3.0~5.0%, diglycerol 3.0~5.0%, iso stearic acid of glycerine ester 1.5~2.5%, 10 distearate 1.5~2.5% of polyglycereol, h-tallow resin 0.3~0.5%, stearic acid 1.0~2.0%, collargol 0.1~0.2%, surplus is Purified Water.Skin-clean cream stability of the present invention is good, can generate the effect repaired to the impaired sebum layer of skin, normal moisture on skin will not be washed away because rinsing with grease, have the effect of that moisturizing is long-acting；In addition, due to being added to sebum remediation composition, promotes skin and be hydrated conclusion ability, resist the pollution of external environment, become moisturizing antiallergic cosmetics with obvious effects.
Description
Technical field
The invention belongs to cosmetic technical field, a kind of weak acid acidic amino acid skin-clean cream and its preparation are concretely related to
Method.
Background technology
Since industry is increasingly flourishing, to the destruction of living environment also getting worse, under this situation, haze, ultraviolet light
With computer radiate it is very big to the injury of skin, nowadays consumers under this environment, cause consumer demographics' dry skin with it is quick
The situation of sense increasingly increases, and therefore, the cleaning product for selecting mild moisturizing again is particularly important, and skin surface normally is to be in
Weakly acidic, for pH value between 4.8~6.5, the maximum original components of keratoderma are exactly a large amount of amino acid element institute
Composition, just because of this, it is the urgent demand of existing consumer to seek a kind of weak acid acidic amino acid skin-clean cream.
Existing cleaning products consumer when in use, the phenomenon for often causing skin exfoliating excessive, normally stopping
The moisturizing ingredient and lipid complex for staying in skin surface wash away, and skin is caused to generate dry, scratchy, sensitive phenomenon.In addition,
It is uniform there is also cannot keep workshop four seasons semi-finished product storeroom environment temperature in existing amino acid skin-clean cream production, it is unable to control
The time of semi-finished product cooling and standings, to cause the control of crystallization time and interior material viscosity and hardness more difficult.
Invention content
The present invention provides a kind of weak acid acidic amino acid skin-clean creams and preparation method thereof, pass through amino acid composite surface of arranging in pairs or groups
The active matter of activating agent and sebum remediation composition compounds, and the easily sensitive production that can be used for a long time with dry skin quality is prepared
Product.The weak acid acidic amino acid skin-clean cream has coordinated sebum remediation composition, can generate the effect of reparation to the impaired sebum layer of skin
Fruit, formula are different from general lotion, and after will not being rinsed because of skin, Normal residence, normal moisture is washed with grease on skin
It goes, there is the ability of supplement in passing, generate the long-acting effect of moisturizing；In addition, due to being added to sebum remediation composition, skin is promoted
It is hydrated conclusion ability, the pollution of external environment is resisted, becomes moisturizing antiallergic cosmetics with obvious effects.
The technical solution adopted in the present invention is：
A kind of weak acid acidic amino acid skin-clean cream, the skin-clean cream are grouped as by the group of following mass percents：Lauroyl paddy
Propylhomoserin sodium 20.0~25.0%, cocounut oil acyl isethionic acid ester sodium 5.0~7.0%, cocoamido sodium propionate 1.5~2.5%, skin
Fat remediation composition 1.5~7.0%, butanediol 15.0~18.0%, methyl propanediol 3.0~5.0%, diglycerol 3.0~
5.0%, iso stearic acid of glycerine ester 1.5~2.5%, Natrulon H-10 distearate 1.5~2.5%, h-tallow resin 0.3
~0.5%, stearic acid 1.0~2.0%, collargol 0.1~0.2%, remaining as Purified Water；Wherein, the sebum reparation combination
Object is made of polyquaternium -51, starfish branch tube algae extract.
Preferably, the mass percent of the polyquaternium -51 is the matter of 0.5~2.0%, starfish branch tube algae extract
It is 1.0~5.0% to measure percentage.
Preferably, the mass percent of the sebum remediation composition is 3.0~5.0%.
Preferably, the skin-clean cream is grouped as by the group of following mass percents：Sodium lauroyl glutamate 25.0%, coconut palm
Oleoyl isethionic acid ester sodium 6.0%, cocoamido sodium propionate 2.0%, polyquaternium -51 1.5%, the extraction of starfish branch tube algae
Object 2.5%, butanediol 18.0%, methyl propanediol 5.0%, diglycerol 3.0%, iso stearic acid of glycerine ester 1.6%, polyglycereol-
10 distearates 2.2%, h-tallow resin 0.4%, stearic acid 1.0%, collargol 0.2%, Purified Water 31.6%.
The present invention makees polyquaternium -51, starfish branch tube algae (CLADOSIPHON NOVAE-CALEDONIAE) extract
It is that sebum remediation composition adds in formula, effective solution consumer skin exfoliating caused by when using clean product
The phenomenon that spending, the moisturizing ingredient Normal residence in skin surface are washed away with lipid complex, and skin is caused to generate dry, thorn
Itch, sensitive phenomenon, the distinctive Phospholipids polymer of sebum remediation composition can make moisture accumulation, and phase is acted on intercellular lipid
Together, skin moisture evaporation can be prevented, due to the structure of polyquaternium -51 unique lipophilic group and hydrophilic group in composition,
After being rinsed repeatedly via clear water, lipophilic group can still stop on skin, so that skin is not had dry-out phenomenon generation, reduce skin
Stimulation, starfish branch tube algae (CLADOSIPHON NOVAE-CALEDONIAE) extract in composition, which has, inhibits hyalomitome
The activity of sour enzyme is compared with antiallergic color glycine, and antianaphylactic effect colorimetric glycine is consistent, in addition, starfish branch tube
The fucoidin of high molecular weight in algae (CLADOSIPHON NOVAE-CALEDONIAE) extract component, for preventing skin
It is dry and cracked, and lipid between sebum is repaired, there is fine effect；The main effect of collargol is to replace preventing for traditional chemical synthesis
Rotten agent, for inflammation and sensitive skin, the preservative of traditional chemical synthesis, which can play one, qualitatively to stimulate, and collargol
The generation of the above problem is avoided well.
Amino acid type surfactant sodium lauroyl glutamate not only have good readily degradable, antibiotic property, safety,
Without anaphylaxis, and since its special structure determines that it has good water solubility, salt-resistance strong as amphoteric surfactant
And there are many excellent properties with pH responses.But find that sodium lauroyl glutamate is using butanediol in the present invention
For solvent when, be easy crystallization and be precipitated, and can be very good to solve above-mentioned ask as cosolvent using a certain amount of methyl propanediol
Topic.
Amino acid skin-clean cream of the present invention does not destroy the normal pH-value of skin, sensitive skin while cleaning skin
It can use, fraction of dosage, you can generate abundant fine foam, long-time service improves the original hydration of skin and concludes energy
Power, gradually constitutes layer protecting film, not tight, do not stimulate, improve the ability that skin resists external world.
A kind of preparation method of weak acid acidic amino acid skin-clean cream, includes the following steps：
(1) by butanediol, methyl propanediol, diglycerol, iso stearic acid of glycerine ester, Natrulon H-10 distearate, heating
To 85~95 DEG C of stirrings to being completely dissolved, it is spare to treat as A phases；
(2) after the completion of waiting for A phases, sodium lauroyl glutamate, cocoamido sodium propionate are added, continues temperature control and is heated to 85
It is spare to treat as B phases to being completely dissolved for~95 DEG C of stirrings；
(3) after waiting for that B phases are completed, Purified Water, cocounut oil acyl isethionic acid ester sodium is sequentially added, continue temperature control be heated to 85~
It is spare to treat as C phases to being completely dissolved for 95 DEG C of stirrings；
(4) when C phases are cooled to 55~65 DEG C, after letting out vacuum pressure, sequentially stearic acid is added, mixing speed 500~
700rpm, it is spare as D phases；
(5) after D phases are completely dissolved, temperature is down to 45~55 DEG C, shows crystallization as sheet-like particle pearl, continues to stir
40~50 DEG C are cooled to, sequentially polyquaternium -51, starfish branch tube algae extract, h-tallow resin, collargol are added, after
It is continuous to mix slowly when being cooled to 35~45 DEG C, compare standard specimen appearance, viscosity, pH value it is errorless after, filtering and discharging utilizes vacuum pressure
It is evacuated to stainless steel freezing thermostat storage barrel, 2~7 DEG C of temperature control is stood after 20~30h to get to a kind of weak acid acidic amino acid clean skin
Cream.
Preferably, in step (3), all step operations are located in fixation type vacuum homogeneous agitated kettle, blade stirring speed
Spend 200~400rpm, after C phases are completely dissolved, open it is fixed vacuumize homogeneous stirring blade, homogeneous speed 1400~
1600rpm, unlatching are evacuated to 0.03~0.05Mpa, after homogeneous stirs 5~15min, continue to vacuumize stirring be cooled to 55~
65℃。
Preferably, the preparation method of the weak acid acidic amino acid skin-clean cream, includes the following steps：
(1) by butanediol, methyl propanediol, diglycerol, iso stearic acid of glycerine ester, Natrulon H-10 distearate, heating
To 92 DEG C of stirrings to being completely dissolved, it is spare to treat as A phases；
(2) after the completion of waiting for A phases, sodium lauroyl glutamate, cocoamido sodium propionate are added, continues temperature control and is heated to 92
DEG C stirring is spare as B phases to being completely dissolved；
(3) after waiting for that B phases are completed, Purified Water, cocounut oil acyl isethionic acid ester sodium is sequentially added, continues temperature control and is heated to 92 DEG C
It is spare to treat as C phases to being completely dissolved for stirring；All step operations are located in fixation type vacuum homogeneous agitated kettle, blade stirring speed
300rpm is spent, after C phases are completely dissolved, unlatching is fixed to vacuumize homogeneous stirring blade, and homogeneous speed 1500rpm, which is opened, to be taken out very
Sky is to 0.04Mpa, after homogeneous stirs 10min, continues to vacuumize stirring being cooled to 60 DEG C；
(4) when C phases are cooled to 60 DEG C, after letting out vacuum pressure, sequentially stearic acid is added, mixing speed 600rpm, when
It is spare at D phases；
(5) after D phases are completely dissolved, temperature is down to 50 DEG C, shows crystallization as sheet-like particle pearl, represents native amino
Acid surfaces activating agent low temperature crystallization is tentatively completed, and is continued stirring and is cooled to 45 DEG C, sequentially by polyquaternium -51, starfish branch tube algae
Extract, h-tallow resin, collargol are added, and continue to mix slowly when being cooled to 40 DEG C, compare standard specimen appearance, viscosity, pH
Be worth it is errorless after, filtering and discharging is evacuated to stainless steel freezing thermostat storage barrel using vacuum pressure, 4 DEG C of temperature control, after standing for 24 hours, pearly-lustre
Crystallization particle diameter is uniform, and viscosity and hardness are consistent with standard specimen to get to a kind of weak acid acidic amino acid skin-clean cream.
The present invention can not lean on traditional high speed homogenization dispersion emulsifying machine individually to complete, if being stored without stainless steel freezing thermostat
The cooperation of bucket, cannot keep that workshop four seasons semi-finished product storeroom environment temperature is uniform, be unable to control semi-finished product cooling and standings when
Between, and obtain the homogeneity of pearly-lustre crystallization particle diameter in the future.The present invention is permanent using high speed homogenization dispersion emulsifying machine and stainless steel freezing
Warm storage barrel is used cooperatively, and is fully solved the control that material in amino acid skin-clean cream stands cooling time and temperature in the future, is reached
To the homogeneity of pearly-lustre crystallization particle diameter, adequately solve amino acid skin-clean cream produce most tired crystallization time step rambunctious with
The control of interior material viscosity and hardness adequately reaches the efficient control node of production economy.
Preferably, the mass percent of the sebum remediation composition is 3.0~5.0%.
Preferably, the skin-clean cream is grouped as by the group of following mass percents：Sodium lauroyl glutamate 25.0%, coconut palm
Oleoyl isethionic acid ester sodium 6.0%, cocoamido sodium propionate 2.0%, polyquaternium -51 1.5%, the extraction of starfish branch tube algae
Object 2.5%, butanediol 18.0%, methyl propanediol 5.0%, diglycerol 3.0%, iso stearic acid of glycerine ester 1.6%, polyglycereol-
10 distearates 2.2%, h-tallow resin 0.4%, stearic acid 1.0%, collargol 0.2%, Purified Water 31.6%.
Beneficial effects of the present invention are：
(1) skin-clean cream sebum reparation performance of keeping humidity is notable, and the polyquaternium -51 in composition, which has, imitates Skin Cell
The component of polymer of membrane molecule structure design synthesis, lipid effect is identical between Skin Cell, can make moisture accumulation, effectively anti-
Only moisture evaporation contains hydrophilic group and lipophilic group in -51 molecular structure of polymer Polyquatemium, so rinsing it repeatedly through water
Afterwards, the part of lipophilic group can still rest on the surface layer of skin, achieve the effect that long-acting moisturizing；
(2) another ingredient starfish branch tube algae extract has fucoidin of the natural polymer amount up to 1,700,000 in composition,
Solid moisture film can be formed on skin, and having improves skin elasticity and moisture-keeping functions, in addition, it is saturating with powerful obstruction
The activity of bright matter acid enzyme effectively inhibits the histamine in skin allergy effect source free, reaches effect of releiving；
(3) sodium lauroyl glutamate contained in product formula is all natural amino acid type surfactant, is free of soap base
Middle alkaline agent, product final ph is faintly acid, consistent with the normal skin pH-value that is averaged, high concentration natural amino acid surface-active
Agent proportioning need to only use a small amount of, so that it may and keep foam tiny careful, easy to clean, biological degradability is high, is cleaning simultaneously, because
Skin cleans in the environment of faintly acid, does not stimulate skin completely, can be used for a long time；
(4) addition of collargol has good antiseptic property instead of traditional synthetic preservative, for skin wound with
Eye irritation, the skin for being more suitable for sensibility are used for a long time；
(5) using butanediol as main solvent, methyl propanediol is cosolvent, it is possible to prevente effectively from amino acid type surfactant
Sodium lauroyl glutamate crystallization is precipitated, and improves the stability of skin-clean cream.
Specific implementation mode
The present invention is further explained in the light of specific embodiments, but invention which is intended to be protected is not limited to
This.
Embodiment 1
A kind of weak acid acidic amino acid skin-clean cream, the skin-clean cream are grouped as by following groups：Purified Water 31.6kg, lauroyl paddy
Propylhomoserin sodium 25.0kg, butanediol 18.0kg, methyl propanediol 5.0kg, cocounut oil acyl isethionic acid ester sodium 6.0kg, diglycerol
3.0kg, cocoamido sodium propionate 2.0kg, iso stearic acid of glycerine ester 1.6kg, Natrulon H-10 distearate 2.2kg, poly- season
- 51 1.5kg of ammonium salt, starfish branch tube algae (CLADOSIPHONNOVAE-CALEDONIAE) extract 2.5kg, h-tallow resin
0.4kg, stearic acid 1.0kg, collargol 0.2kg.
The preparation method of above-mentioned weak acid acidic amino acid skin-clean cream, includes the following steps：
(1) first by butanediol, methyl propanediol, diglycerol, iso stearic acid of glycerine ester, Natrulon H-10 distearate,
92 DEG C of stirrings are heated to being completely dissolved, it is spare to treat as A phases；
(2) after the completion of waiting for A phases, sodium lauroyl glutamate, cocoamido sodium propionate are added, continues temperature control and is heated to 92
DEG C stirring is spare as B phases to being completely dissolved；
(3) after waiting for that B phases are completed, Purified Water, cocounut oil acyl isethionic acid ester sodium is sequentially added, continues temperature control and is heated to 92 DEG C
Stirring is to being completely dissolved, and spare as C phases, all step operations are located in fixation type vacuum homogeneous agitated kettle, blade stirring speed
300rpm is spent, after C phases are completely dissolved, unlatching is fixed to vacuumize homogeneous stirring blade, and homogeneous speed 1500rpm, which is opened, to be taken out very
Sky is to 0.04Mpa, after homogeneous stirs 10min, continues to vacuumize stirring being cooled to 60 DEG C；
(4) when C phases are cooled to 60 DEG C, after letting out vacuum pressure, sequentially the group ingredient stearic acid of interior material is added, stirring speed
600rpm is spent, it is spare as D phases；
(5) after D phases are completely dissolved, when interior material temperature degree is down to 50 DEG C, crystallization, generation as sheet-like particle pearl be will present out
Table natural amino acid surfactant low temperature crystallization is tentatively completed, and continues stirring when being cooled to 45 DEG C, sebum is sequentially repaired group
Close object (polyquaternium -51, starfish branch tube algae (CLADOSIPHONNOVAE-CALEDONIAE) extract), h-tallow resin,
Collargol is added, and continues to mix slowly when being cooled to 40 DEG C, compare standard specimen appearance, viscosity, pH value it is errorless after, after filtering and discharging,
Interior material is evacuated to stainless steel freezing thermostat storage barrel using vacuum pressure, 4 DEG C of temperature control, after standing for 24 hours, pearly-lustre crystallization particle diameter is equal
One, viscosity is consistent with hardness with standard specimen, you can obtains a kind of weak acid acidic amino acid skin-clean cream.
The stainless steel freezing thermostat storage barrel inner wall uses 316 stainless steel steel of SUS, acid and alkali-resistance, can timing, controllable
Temperature is conveniently operated.It solves after interior material after traditional stirring emulsifying equipment production stands for 24 hours naturally, can not effectively control
The maintenance of pearly-lustre crystallization particle diameter and interior material final viscosity hardness, also, do not influenced by four seasons workshop condition temperature.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 90.5% and 95.6% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 90.8% and 98.7% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 95.3% and 97.8% trier to there is moderate to improve and be obviously improved respectively；
The product is can be seen that increasing skin moisture-keeping, soothing the skin tingling sensation, reduction from the assessment result of trier
Skin allergy rate has different degrees of significantly improve.
Embodiment 2
A kind of weak acid acidic amino acid skin-clean cream, the skin-clean cream are grouped as by following groups：Purified Water 30.9kg, lauroyl paddy
Propylhomoserin sodium 23.0kg, butanediol 17.0kg, methyl propanediol 4.0kg, cocounut oil acyl isethionic acid ester sodium 7.0kg, diglycerol
4.0kg, cocoamido sodium propionate 2.0kg, iso stearic acid of glycerine ester 2.0kg, Natrulon H-10 distearate 2.0kg, poly- season
- 51 1.8kg of ammonium salt, starfish branch tube algae (CLADOSIPHONNOVAE-CALEDONIAE) extract 3.2kg, h-tallow resin
0.4kg, stearic acid 1.5kg, collargol 0.2kg.Preparation process is with reference to embodiment 1.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 85.9% and 90.8% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 88.4% and 90.6% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 89.7% and 90.8% trier to there is moderate to improve and be obviously improved respectively；
The product is can be seen that increasing skin moisture-keeping, soothing the skin tingling sensation, reduction from the assessment result of trier
Skin allergy rate has different degrees of significantly improve.
Embodiment 3
A kind of weak acid acidic amino acid skin-clean cream, the skin-clean cream are grouped as by following groups：Purified Water 33.6kg, lauroyl paddy
Propylhomoserin sodium 25.0kg, butanediol 18.0kg, methyl propanediol 5.0kg, cocounut oil acyl isethionic acid ester sodium 6.0kg, diglycerol
3.0kg, cocoamido sodium propionate 2.0kg, iso stearic acid of glycerine ester 1.6kg, Natrulon H-10 distearate 2.2kg, poly- season
- 51 0.5kg of ammonium salt, starfish branch tube algae (CLADOSIPHONNOVAE-CALEDONIAE) extract 1.5kg, h-tallow resin
0.4kg, stearic acid 1.0kg, collargol 0.2kg.Preparation process is with reference to embodiment 1.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 65.9% and 60.8% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 68.4% and 60.6% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 69.7% and 60.8% trier to there is moderate to improve and be obviously improved respectively；
The product is can be seen that increasing skin moisture-keeping, soothing the skin tingling sensation, reduction from the assessment result of trier
Skin allergy rate has different degrees of significantly improve.
Embodiment 4
A kind of weak acid acidic amino acid skin-clean cream, the skin-clean cream are grouped as by following groups：Purified Water 32.1kg, lauroyl paddy
Propylhomoserin sodium 25.0kg, butanediol 18.0kg, methyl propanediol 5.0kg, cocounut oil acyl isethionic acid ester sodium 6.0kg, diglycerol
3.0kg, cocoamido sodium propionate 2.0kg, iso stearic acid of glycerine ester 1.6kg, Natrulon H-10 distearate 2.2kg, poly- season
- 51 1.2kg of ammonium salt, starfish branch tube algae (CLADOSIPHONNOVAE-CALEDONIAE) extract 1.8kg, h-tallow resin
0.4kg, stearic acid 1.0kg, collargol 0.2kg.Preparation process is with reference to embodiment 1.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 80.2% and 88.8% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 83.4% and 87.5% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 84.2% and 87.9% trier to there is moderate to improve and be obviously improved respectively；
The product is can be seen that increasing skin moisture-keeping, soothing the skin tingling sensation, reduction from the assessment result of trier
Skin allergy rate has different degrees of significantly improve.
Embodiment 5
A kind of weak acid acidic amino acid skin-clean cream, the skin-clean cream are grouped as by following groups：Purified Water 46.6kg, lauroyl paddy
Propylhomoserin sodium 20.0kg, butanediol 15.0kg, methyl propanediol 3.0kg, cocounut oil acyl isethionic acid ester sodium 5.0kg, diglycerol
3.0kg, cocoamido sodium propionate 1.5kg, iso stearic acid of glycerine ester 1.5kg, Natrulon H-10 distearate 1.5kg, poly- season
- 51 0.5kg of ammonium salt, starfish branch tube algae (CLADOSIPHONNOVAE-CALEDONIAE) extract 1.0kg, h-tallow resin
0.3kg, stearic acid 1.0kg, collargol 0.1kg.Preparation process is with reference to embodiment 1.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 66.2% and 80.2% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 50.3% and 60.4% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 48.4% and 56.8% trier to there is moderate to improve and be obviously improved respectively.
Embodiment 6
A kind of weak acid acidic amino acid skin-clean cream, the skin-clean cream are grouped as by following groups：Purified Water 22.8kg, lauroyl paddy
Propylhomoserin sodium 25.0kg, butanediol 18.0kg, methyl propanediol 5.0kg, cocounut oil acyl isethionic acid ester sodium 7.0kg, diglycerol
5.0kg, cocoamido sodium propionate 2.5kg, iso stearic acid of glycerine ester 2.5kg, Natrulon H-10 distearate 2.5kg, poly- season
- 51 2.0kg of ammonium salt, starfish branch tube algae (CLADOSIPHONNOVAE-CALEDONIAE) extract 5.0kg, h-tallow resin
0.5kg, stearic acid 2.0kg, collargol 0.2kg.Preparation process is with reference to embodiment 1.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 60.2% and 75.6% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 45.6% and 52.4% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 40.1% and 50.2% trier to there is moderate to improve and be obviously improved respectively.
Embodiment 7
A kind of weak acid acidic amino acid skin-clean cream, formula composition is with reference to embodiment 1.
The preparation method of above-mentioned weak acid acidic amino acid skin-clean cream, includes the following steps：
(1) first by butanediol, methyl propanediol, diglycerol, iso stearic acid of glycerine ester, Natrulon H-10 distearate,
85 DEG C of stirrings are heated to being completely dissolved, it is spare to treat as A phases；
(2) after the completion of waiting for A phases, sodium lauroyl glutamate, cocoamido sodium propionate are added, continues temperature control and is heated to 85
DEG C stirring is spare as B phases to being completely dissolved；
(3) after waiting for that B phases are completed, Purified Water, cocounut oil acyl isethionic acid ester sodium is sequentially added, continues temperature control and is heated to 85 DEG C
Stirring is to being completely dissolved, and spare as C phases, all step operations are located in fixation type vacuum homogeneous agitated kettle, blade stirring speed
200rpm is spent, after C phases are completely dissolved, unlatching is fixed to vacuumize homogeneous stirring blade, and homogeneous speed 1400rpm, which is opened, to be taken out very
Sky is to 0.03Mpa, after homogeneous stirs 5min, continues to vacuumize stirring being cooled to 55 DEG C；
(4) when C phases are cooled to 55 DEG C, after letting out vacuum pressure, sequentially the group ingredient stearic acid of interior material is added, stirring speed
500rpm is spent, it is spare as D phases；
(5) after D phases are completely dissolved, when interior material temperature degree is down to 50 DEG C, crystallization as sheet-like particle pearl is will present out, after
When continuous stirring is cooled to 40 DEG C, sequentially by sebum remediation composition (polyquaternium -51, starfish branch tube algae extract), hydrogenation ox
Oleoresin, collargol are added, and continue to mix slowly when being cooled to 35 DEG C, compare standard specimen appearance, viscosity, pH value it is errorless after, filtering
After discharging, interior material is evacuated to stainless steel freezing thermostat storage barrel using vacuum pressure, 7 DEG C of temperature control, after standing for 24 hours, pearly-lustre crystallizes
Uniform particle diameter, viscosity are consistent with hardness with standard specimen, you can obtain a kind of weak acid acidic amino acid skin-clean cream.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 84.3% and 85.6% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 82.1% and 85.7% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 81.6% and 86.7% trier to there is moderate to improve and be obviously improved respectively.
The product is can be seen that increasing skin moisture-keeping, soothing the skin tingling sensation, reduction from the assessment result of trier
Skin allergy rate has different degrees of significantly improve.
Embodiment 8
A kind of weak acid acidic amino acid skin-clean cream, formula composition is with reference to embodiment 1.
The preparation method of above-mentioned weak acid acidic amino acid skin-clean cream, includes the following steps：
(1) first by butanediol, methyl propanediol, diglycerol, iso stearic acid of glycerine ester, Natrulon H-10 distearate,
95 DEG C of stirrings are heated to being completely dissolved, it is spare to treat as A phases；
(2) after the completion of waiting for A phases, sodium lauroyl glutamate, cocoamido sodium propionate are added, continues temperature control and is heated to 95
DEG C stirring is spare as B phases to being completely dissolved；
(3) after waiting for that B phases are completed, Purified Water, cocounut oil acyl isethionic acid ester sodium is sequentially added, continues temperature control and is heated to 95 DEG C
Stirring is to being completely dissolved, and spare as C phases, all step operations are located in fixation type vacuum homogeneous agitated kettle, blade stirring speed
400rpm is spent, after C phases are completely dissolved, unlatching is fixed to vacuumize homogeneous stirring blade, and homogeneous speed 1600rpm, which is opened, to be taken out very
Sky is to 0.05Mpa, after homogeneous stirs 15min, continues to vacuumize stirring being cooled to 65 DEG C；
(4) when C phases are cooled to 65 DEG C, after letting out vacuum pressure, sequentially the group ingredient stearic acid of interior material is added, stirring speed
700rpm is spent, it is spare as D phases；
(5) after D phases are completely dissolved, when interior material temperature degree is down to 50 DEG C, crystallization as sheet-like particle pearl is will present out, after
When continuous stirring is cooled to 45 DEG C, sequentially by sebum remediation composition (polyquaternium -51, starfish branch tube algae extract), hydrogenation ox
Oleoresin, collargol are added, and continue to mix slowly when being cooled to 40 DEG C, compare standard specimen appearance, viscosity, pH value it is errorless after, filtering
After discharging, interior material is evacuated to stainless steel freezing thermostat storage barrel using vacuum pressure, 2 DEG C of temperature control, after standing for 24 hours, pearly-lustre crystallizes
Uniform particle diameter, viscosity are consistent with hardness with standard specimen, you can obtain a kind of weak acid acidic amino acid skin-clean cream.
Measure of merit：
Using 550 triers as research object, wherein male 200, women 350, the oldest 43 years old, minimum 20
Year, average age 25 years old or so, trier repair relevant indices after 28 days using skin-clean cream of the present invention to sebum moisturizing
Degree result is as follows：
Increase skin moisture-keeping：There is 82.7% and 84.2% trier to there is moderate to improve and be obviously improved respectively；
Soothe the skin tingling sensation：There is 81.7% and 83.6% trier to there is moderate to improve and be obviously improved respectively；
Reduce skin allergy rate：There is 82.3% and 84.5% trier to there is moderate to improve and be obviously improved respectively.
The product is can be seen that increasing skin moisture-keeping, soothing the skin tingling sensation, reduction from the assessment result of trier
Skin allergy rate has different degrees of significantly improve.
Embodiment 9
Formula composition does not add cosolvent methyl propanediol with reference to embodiment 1 in formula composition.
Stability test
Embodiment 10
Formula composition does not add cosolvent methyl propanediol with reference to embodiment 1 in formula composition, while increasing butanediol use
It measures to 23kg.
Stability test
Claims (9)
1. a kind of weak acid acidic amino acid skin-clean cream, it is characterised in that：The skin-clean cream is grouped as by the group of following mass percents：
Sodium lauroyl glutamate 20.0~25.0%, cocounut oil acyl isethionic acid ester sodium 5.0~7.0%, cocoamido sodium propionate 1.5~
2.5%, sebum remediation composition 1.5~7.0%, butanediol 15.0~18.0%, methyl propanediol 3.0~5.0%, diglycerol
3.0~5.0%, iso stearic acid of glycerine ester 1.5~2.5%, Natrulon H-10 distearate 1.5~2.5%, h-tallow tree
Fat 0.3~0.5%, stearic acid 1.0~2.0%, collargol 0.1~0.2%, remaining as Purified Water；Wherein, the sebum reparation
Composition is made of polyquaternium -51, starfish branch tube algae extract.
2. weak acid acidic amino acid skin-clean cream according to claim 1, it is characterised in that：The quality hundred of the polyquaternium -51
It is 1.0~5.0% to divide than the mass percent for 0.5~2.0%, starfish branch tube algae extract.
3. weak acid acidic amino acid skin-clean cream according to claim 1, it is characterised in that：The quality of the sebum remediation composition
Percentage is 3.0~5.0%.
4. weak acid acidic amino acid skin-clean cream according to claim 3, it is characterised in that：The skin-clean cream is by following quality percentages
The group of ratio is grouped as：Sodium lauroyl glutamate 25.0%, cocounut oil acyl isethionic acid ester sodium 6.0%, cocoamido sodium propionate
2.0%, polyquaternium -51 1.5%, starfish branch tube algae extract 2.5%, butanediol 18.0%, methyl propanediol 5.0%, double
Glycerine 3.0%, iso stearic acid of glycerine ester 1.6%, Natrulon H-10 distearate 2.2%, h-tallow resin 0.4%, tristearin
Acid 1.0%, collargol 0.2%, Purified Water 31.6%.
5. the preparation method of weak acid acidic amino acid skin-clean cream described in a kind of claim 1, it is characterised in that include the following steps：
(1) by butanediol, methyl propanediol, diglycerol, iso stearic acid of glycerine ester, Natrulon H-10 distearate, 85 are heated to
It is spare to treat as A phases to being completely dissolved for~95 DEG C of stirrings；
(2) after the completion of waiting for A phases, sodium lauroyl glutamate, cocoamido sodium propionate are added, continues temperature control and is heated to 85~95
DEG C stirring is spare as B phases to being completely dissolved；
(3) after waiting for that B phases are completed, Purified Water, cocounut oil acyl isethionic acid ester sodium is sequentially added, continues temperature control and is heated to 85~95 DEG C
It is spare to treat as C phases to being completely dissolved for stirring；
(4) when C phases are cooled to 55~65 DEG C, after letting out vacuum pressure, sequentially stearic acid is added, mixing speed 500~
700rpm, it is spare as D phases；
(5) after D phases are completely dissolved, temperature is down to 45~55 DEG C, shows crystallization as sheet-like particle pearl, continues stirring cooling
To 40~50 DEG C, sequentially polyquaternium -51, starfish branch tube algae extract, h-tallow resin, collargol are added, continued slow
When speed stirring is cooled to 35~45 DEG C, after comparison standard specimen appearance, viscosity, pH value are errorless, filtering and discharging is evacuated to using vacuum pressure
Stainless steel freezing thermostat storage barrel, 2~7 DEG C of temperature control are stood after 20~30h to get to a kind of weak acid acidic amino acid skin-clean cream.
6. the preparation method of weak acid acidic amino acid skin-clean cream according to claim 5, it is characterised in that：In step (3), own
Step operation is located in fixation type vacuum homogeneous agitated kettle, and blade 200~400rpm of mixing speed is opened after C phases are completely dissolved
Open it is fixed vacuumize homogeneous stirring blade, homogeneous 1400~1600rpm of speed, unlatching is evacuated to 0.03~0.05Mpa,
After matter stirs 5~15min, continue to vacuumize stirring being cooled to 55~65 DEG C.
7. the preparation method of weak acid acidic amino acid skin-clean cream according to claim 5, it is characterised in that include the following steps：
(1) by butanediol, methyl propanediol, diglycerol, iso stearic acid of glycerine ester, Natrulon H-10 distearate, 92 are heated to
DEG C stirring is spare as A phases to being completely dissolved；
(2) after the completion of waiting for A phases, sodium lauroyl glutamate, cocoamido sodium propionate are added, continuation temperature control is heated to 92 DEG C and stirs
It mixes to being completely dissolved, it is spare to treat as B phases；
(3) after waiting for that B phases are completed, Purified Water, cocounut oil acyl isethionic acid ester sodium is sequentially added, continues temperature control and is heated to 92 DEG C of stirrings
To being completely dissolved, it is spare to treat as C phases；All step operations are located in fixation type vacuum homogeneous agitated kettle, blade mixing speed
300rpm, after C phases are completely dissolved, unlatching is fixed to vacuumize homogeneous stirring blade, and the 1500rpm unlatchings of homogeneous speed vacuumize
To 0.04Mpa, after homogeneous stirs 10min, continue to vacuumize stirring being cooled to 60 DEG C；
(4) when C phases are cooled to 60 DEG C, after letting out vacuum pressure, sequentially stearic acid is added, mixing speed 600rpm, treats as D phases
It is spare；
(5) after D phases are completely dissolved, temperature is down to 50 DEG C, shows crystallization as sheet-like particle pearl, continues stirring and is cooled to 45
DEG C, sequentially polyquaternium -51, starfish branch tube algae extract, h-tallow resin, collargol are added, continue to mix slowly drop
When temperature is to 40 DEG C, after comparison standard specimen appearance, viscosity, pH value are errorless, filtering and discharging is evacuated to stainless steel using vacuum pressure and freezes perseverance
Warm storage barrel, 4 DEG C of temperature control, to get to a kind of weak acid acidic amino acid skin-clean cream after standing for 24 hours.
8. the preparation method of weak acid acidic amino acid skin-clean cream according to claim 5, it is characterised in that：The sebum reparation group
The mass percent for closing object is 3.0~5.0%.
9. the preparation method of weak acid acidic amino acid skin-clean cream according to claim 8, it is characterised in that the skin-clean cream is under
The group for stating mass percent is grouped as：Sodium lauroyl glutamate 25.0%, cocounut oil acyl isethionic acid ester sodium 6.0%, cocounut oil acyl ammonia
Base sodium propionate 2.0%, polyquaternium -51 1.5%, starfish branch tube algae extract 2.5%, butanediol 18.0%, methyl propanediol
5.0%, diglycerol 3.0%, iso stearic acid of glycerine ester 1.6%, Natrulon H-10 distearate 2.2%, h-tallow resin
0.4%, stearic acid 1.0%, collargol 0.2%, Purified Water 31.6%.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810346177.5A CN108272665A (en) | 2018-04-18 | 2018-04-18 | A kind of weak acid acidic amino acid skin-clean cream and preparation method thereof |
| TW108103519A TWI686207B (en) | 2018-04-18 | 2019-01-30 | Cleansing cream and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810346177.5A CN108272665A (en) | 2018-04-18 | 2018-04-18 | A kind of weak acid acidic amino acid skin-clean cream and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108272665A true CN108272665A (en) | 2018-07-13 |
Family
ID=62811703
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810346177.5A Pending CN108272665A (en) | 2018-04-18 | 2018-04-18 | A kind of weak acid acidic amino acid skin-clean cream and preparation method thereof |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN108272665A (en) |
| TW (1) | TWI686207B (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108888589A (en) * | 2018-07-27 | 2018-11-27 | 珀莱雅化妆品股份有限公司 | A kind of antiallergic moisture-keeping composition containing seawater |
| CN110339111A (en) * | 2019-07-19 | 2019-10-18 | 伊犁弥玥泉生物科技有限公司 | A kind of cleaning compositions of the hot spring containing mineral |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048653A (en) * | 2011-01-06 | 2011-05-11 | 广州壹凡化工有限公司 | Amino acid type weak acid facial cleanser and preparation method thereof |
| CN105030564A (en) * | 2015-08-18 | 2015-11-11 | 广东轻工职业技术学院 | Composition with long-lasting moisturizing function and application of composition |
| CN107308028A (en) * | 2017-04-01 | 2017-11-03 | 上海乐谷娜生物科技有限公司 | Cutaneous penetration essence |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201641099A (en) * | 2015-05-19 | 2016-12-01 | 嘉藥學校財團法人嘉南藥理大學 | Low-irritating shampoo composition |
-
2018
- 2018-04-18 CN CN201810346177.5A patent/CN108272665A/en active Pending
-
2019
- 2019-01-30 TW TW108103519A patent/TWI686207B/en not_active IP Right Cessation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102048653A (en) * | 2011-01-06 | 2011-05-11 | 广州壹凡化工有限公司 | Amino acid type weak acid facial cleanser and preparation method thereof |
| CN105030564A (en) * | 2015-08-18 | 2015-11-11 | 广东轻工职业技术学院 | Composition with long-lasting moisturizing function and application of composition |
| CN107308028A (en) * | 2017-04-01 | 2017-11-03 | 上海乐谷娜生物科技有限公司 | Cutaneous penetration essence |
Non-Patent Citations (2)
| Title |
|---|
| 朱立弘: "《2-甲基-1,3-丙二醇—一种新的个人护理品用原料》", 《香料香精化妆品》 * |
| 王建新: "《化妆品植物原料大全》", 30 June 2012, 中国纺织出版社 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108888589A (en) * | 2018-07-27 | 2018-11-27 | 珀莱雅化妆品股份有限公司 | A kind of antiallergic moisture-keeping composition containing seawater |
| CN110339111A (en) * | 2019-07-19 | 2019-10-18 | 伊犁弥玥泉生物科技有限公司 | A kind of cleaning compositions of the hot spring containing mineral |
Also Published As
| Publication number | Publication date |
|---|---|
| TWI686207B (en) | 2020-03-01 |
| TW201943404A (en) | 2019-11-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105997678B (en) | One kind washing the two-in-one baby shower gel of shield | |
| CN107296771A (en) | A kind of desquamation compositions and extra quality multiple-effect are without silicone oil shampoo | |
| CN109381363A (en) | A kind of amino acid shampoo and preparation method thereof | |
| CN109846792B (en) | Micro-bead moisturizing skin care product and preparation method thereof | |
| CN103622864A (en) | Multifunctional aloe gel and preparation method thereof | |
| CN110123721B (en) | Shampoo composition for improving oily scalp | |
| CN102697668A (en) | Hair washing method of foaming agent type shampoo | |
| CN105997572B (en) | Facial cleanser containing nano graphene and preparation method thereof | |
| CN101011319A (en) | Mineral salt shampoo | |
| CN109464300A (en) | Foam mildy wash and preparation method thereof after one kind | |
| CN107281014A (en) | One kind nourishes strong hair without silicone oil shampoo | |
| CN105476950B (en) | Moisturizing foam mildy wash and preparation method thereof | |
| KR19980703589A (en) | Surfactant composition | |
| CN107375063A (en) | A kind of shower cream and preparation method | |
| CN109401869A (en) | Liquid cleansing composition and its preparation method and application | |
| CN108272665A (en) | A kind of weak acid acidic amino acid skin-clean cream and preparation method thereof | |
| WO2020077956A1 (en) | Silk protein component-contained antidandruff and antipruritic hair cleaning and nourishing composition and preparation method therefor | |
| CN110423654A (en) | Clean piece of the mosquito-proof laundry of one kind and preparation method thereof | |
| CN104000766A (en) | Effective gentle makeup-removing micelle liquid | |
| CN108865490A (en) | The fruits and vegetables cleaning agent and preparation method thereof of microemulsion dosage removal pesticide residue | |
| CN106551819A (en) | A kind of emulsifying composition of high fat content, preparation method and applications | |
| JP2007518678A (en) | Highly unsaponifiable matter and method using the same | |
| CN106109275A (en) | A kind of foaming bath oil rich in vegetable oil and preparation method thereof | |
| CN108587823A (en) | A kind of soap base compound, preparation method and its usage | |
| JP5912397B2 (en) | Cosmetic liquid, cosmetic liquid production method and cosmetic method |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Zhou Dingli Inventor after: Liu Yizhi Inventor after: Zhang Yong Inventor before: Liu Yizhi Inventor before: Zhou Dingli Inventor before: Zhang Yong |
|
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180713 |