TW201641099A - Low-irritating shampoo composition - Google Patents

Abstract

The invention relates to a low-irritating shampoo composition, comprising 0.1 wt% Coco-Glucoside, 5 wt% Disodium Cocoamphodiacetate, 10 wt% Cocoamidopropyl Betaine, 1 wt% Sodium Lauroyl Oat Amino Acids, 5 wt% PEG 18 Glyceryl Oleate/Cocoate, 1 wt% Glycerin, 0.5 wt% Imidazolinyl Urea, 0.2 wt% Citric Acid, 0.2 wt% Phenoxyethanol, 0.2 wt% Methylparaben, 0.1wt% Disodium EDTA, and the remaining weight percent of solvent. Accordingly, the low-irritating shampoo composition decreases irritation of users' skin caused by the conventional shampoo.

Description

Low irritant shampoo composition

The present invention relates to a low irritant shampoo composition, and more particularly to a shampoo composition having a specific formulation which reduces irritation to the skin of a user.

The components of the general hair cleansing agent include Surfactant, Dimethicone, and nutrient conditioning ingredients (such as vitamins, plant extracts), etc.; the purpose of the surfactant is to remove the oil on the hair and attach foreign matter; It is also known as a emollient, which adheres to the surface of the hair to form a hydrophobic film and makes the hair soft and smooth. The manufacturer can arbitrarily adjust the various components of the hair cleaning agent according to the needs, and the different fragrances can make the hair cleaning agent have a special fragrance to attract customers to purchase. However, commercially available hair-cleaning agents are usually added with a highly irritating chemical additive in order to achieve a better cleaning effect, so that long-term use is likely to cause damage to the user's skin. For example, improper use of surfactants leads to excessive defatting, which can cause dryness of the hair and skin, and even worse, hair follicles can be damaged, resulting in easy hair loss or redness, swelling and itching of the skin.

Therefore, how to develop a hair cleansing agent with good cleansing power and no irritating and toxic is the direction of the relevant industry.

Nowadays, the inventor is in view of the fact that the above-mentioned existing hair cleaning agent still has many defects in actual use, so it is a tireless spirit and is supplemented by its rich professional knowledge and years of practical experience. Improvements have been made and the present invention has been developed based on this.

SUMMARY OF THE INVENTION A primary object of the present invention is to provide a low irritation shampoo composition which refers to a shampoo composition having a specific formulation for reducing irritation to the skin of a user.

In order to achieve the above-mentioned object, the present invention provides a low irritant shampoo composition comprising 0.1% by weight of Coco-Glucoside, 5% Disodium Cocoamphodiacetate. , 10% Cocoamidopropyl Betaine, 1% Sodium Lauroyl Oat Amino Acids, 5% PEG-18 Glycerol Oleate/Cocoate (PEG 18 Glyceryl Oleate/Cocoate ), 1% glycerol (Glycerin), 0.5% diazolidinyl Urea, 0.2% citric acid, 0.2% Phenoxyethanol, 0.2% methyl benzoate 0.1% ethylenediamine tetraethyl disodium (Disodium EDTA), and the remaining weight percent solvent.

In one embodiment of the invention, the solvent is deionized water.

In an embodiment of the present invention, the low irritation shampoo composition may further add 0.1 to 1% perfume.

The objects and advantages of the present invention will be described in the light of the accompanying drawings and the accompanying claims.

A low irritant shampoo composition of the invention comprising 0.1% by weight of Coco-Glucoside, 5% Disodium Cocoamphodiacetate, 10% alkyl hydrazine Cocoamidopropyl Betaine, 1% Sodium Lauroyl Oat Amino Acids, 5% PEG-18 Glyceryl Oleate/Cocoate, 1% Glycerin Glycerin), 0.5% Imidazolinyl Urea, 0.2% Citric Acid, 0.2% Phenoxyethanol, 0.2% Methylparaben, 0.1% Ethylenediamine Ethyl disodium (Disodium EDTA), and a residual weight percentage of the solvent; wherein the solvent may be, for example, deionized water, and optionally 0.1 to 1% perfume may be further added.

Among the above ingredients, Coco-Glucoside, Disodium Cocoamphodiacetate, Cocoamidopropyl Betaine, and Sodium Lauroyl Oat Amino Acids) is a surfactant; PEG-18 Glyceryl Oleate/Cocoate is an emulsifier; Glycerin is a humectant; Citric Acid and phenoxyethanol ( Phenoxyethanol is a hair care ingredient; Methylparaben is a preservative; Disodium EDTA is a metal chelating agent.

In addition, the scope of the invention may be further exemplified by the following specific examples, which are not intended to limit the scope of the invention.

Example 1: Testing the irritancy of this formula shampoo and commercially available shampoo

The shampoo formulation of the present invention comprises 16.1% by weight of surfactant (0.1% cocoyl-glucoside, 5% disodium cocoyl diacetate, 10% alkylguanamine betaine, 1% laurel oatmeal) Amino acid sodium), 5% emulsifier (PEG-18 glyceryl oleate/cocoate), 1.5% humectant (1% glycerol, 0.5% diazolidinyl imidazole), 0.4% hair care ingredients (0.2%) Citric acid, 0.2% phenoxyethanol), 0.2% preservative (methyl benzoate), 0.1% chelating agent (ethylenediamine tetraethyl disodium), and 76.7% deionized water.

Commercially available shampoo ingredients are water, surfactant (Ammonium Laureth Sulfate, Sodium Lauroyl Sarcosinate, Cocamide Methyl MEA, Cocamidopropyl Betaine, Propylene Glycol, Sodium Chloride, Fragrace, Polyqaternium-10, Citric Acid, Menthol, Panthenol, Allantion, Disodium EDTA, Hydrolyzed Rhodophycea Extract, Rhodophycea Extrac t, Polyqaternium-7, Methylchloroisothiazolinone and Methylisothiazolinone. The most important difference between the shampoo formulations of the present invention and commercially available shampoo formulations is the selection and matching of surfactant components.

The irritant test was carried out using the "Identification reagents, methods and kits for replacing animal and cytotoxicity tests" of the No. I359270 published by the inventor on March 1, 2012. The reagent was added to a 96 well plate, and 200 μl of the reagent was added per well; 4 μl of the analyte was added and uniformly mixed for 30 seconds, but air bubbles were avoided. 4 μl of distilled water (D.W.) was used as a control group. The absorbance was measured by ELISA READER wavelength 405 nm, and the absorbance value of the control group was subtracted from the result data. To determine the stimulation intensity, proceed as follows: (a) Add the reagent to the 96 well plate, add 200 μl of reagent per well; (b) Add 2, 10, 20, 60 or 150 μl of the test substance per well, respectively. 10 seconds, then mix and mix for 30 seconds, but avoid bubbles, if you have bubbles, be careful to remove the bubbles. If the substance to be tested has color, add 200 μl of water as the background color to the control group (c) to measure the absorbance at ELISA READER wavelength 405 nm, and subtract the background color. The absorbance value of the group is the dose data; and (d) note whether the first four doses 2, 10, 20, 60 μl have an absorbance greater than 0.2 (slight stimulation or above), if any, the first four doses are selected (2, 10, 20, 60μl) The highest absorbance value to determine the stimulus intensity; if not, select the highest absorbance value of the first five doses (2, 10, 20, 60, 150μl) to determine the stimulus intensity. The contrast values of reagent turbidity and Draize test eye mucosa stimulation intensity are shown in Table 1:

Table I

Detection quality control (QC): The positive control group was 150 μl of 95% ethanol, added with 200 μl of reagent, allowed to stand for ten seconds, and then stirred for 30 seconds, requiring O.D 1.5 or more. The negative control group was added with 200 μl of reagent in 150 μl of 0.9% physiological saline, allowed to stand for ten seconds, and then stirred for 30 seconds, and O.D 0.2 or less was required.

The results are shown in the first figure. Generally, the commercially available shampoo has a irritating turbid color after being tested by non-animal safety testing reagents. In contrast, the shampoo prepared by this formula is non-irritating after being tested by non-animal safety testing reagents. Transparent color. Please refer to Table 2 for the data sheet for the detection of hair cleansers using non-animal safety test reagents. Compared with commercially available shampoos, the OD value of this formula shampoo is maintained even at a dose of 150 μl. 0.1, it can be seen that the stimulation intensity is none, very slight stimulation, and has excellent safety.

Table 2: Non-animal safety testing reagents

From the test results, it can be seen that the shampoo formulation developed this time has lower irritancy and toxicity than the commercially available shampoo, so the long-term use will not harm the user's skin. In addition, the low irritation shampoo developed by the present invention not only has cleansing power and foaming property, but also adds many moisturizing ingredients to enhance the moisturizing property of the shampoo. Thereby, the present invention provides a good choice for users who value product safety.

It can be seen from the above description that the present invention has the following advantages compared with the prior art:

1. The present invention takes a relatively long time to develop a combination of different surfactants, and develops a shampoo formula containing the best ingredients and low irritation, which can solve the problem of skin damage easily caused by commercially available shampoo after prolonged use. .

2. The low irritant shampoo of the present invention adds a lot of moisturizing ingredients, not only has good cleansing power, but also greatly improves the moisturizing property of the shampoo.

In summary, the low irritation shampoo composition of the present invention can achieve the intended use efficiency by the above disclosed embodiments, and the present invention has not been disclosed before the application, and has been fully in compliance with the patent. The rules and requirements of the law.爰Issuing an application for a patent for invention in accordance with the law, and asking for a review, and granting a patent, is truly sensible.

The illustrations and descriptions of the present invention are merely preferred embodiments of the present invention, and are not intended to limit the scope of the present invention; those skilled in the art, which are characterized by the scope of the present invention, Equivalent variations or modifications are considered to be within the scope of the design of the invention.

No

First panel: Comparison of the irritancy of a preferred embodiment of the invention with a commercially available shampoo.

Claims (3)

A low irritant shampoo composition comprising 0.1% by weight Coco-Glucoside, 5% Disodium Cocoamphodiacetate, 10% alkylguanamine beet Base (Cocoamidopropyl Betaine), 1% Sodium Lauroyl Oat Amino Acids, 5% PEG-18 Glyceryl Oleate/Cocoate, 1% Glycerin , 0.5% Diamidazolinyl Urea, 0.2% Citric Acid, 0.2% Phenoxyethanol, 0.2% Methylparaben, 0.1% Ethylenediamine Tetraethyl Disodium EDTA, and the remaining weight percent solvent. The low irritation shampoo composition of claim 1, wherein the solvent is deionized water. The low irritation shampoo composition according to claim 1, wherein 0.1 to 1% of the perfume is further added.