CN1081623C - 苯衍生物 - Google Patents

苯衍生物 Download PDF

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Publication number
CN1081623C
CN1081623C CN96191624A CN96191624A CN1081623C CN 1081623 C CN1081623 C CN 1081623C CN 96191624 A CN96191624 A CN 96191624A CN 96191624 A CN96191624 A CN 96191624A CN 1081623 C CN1081623 C CN 1081623C
Authority
CN
China
Prior art keywords
group
formula
pharmacology
benzene derivative
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN96191624A
Other languages
English (en)
Chinese (zh)
Other versions
CN1173169A (zh
Inventor
长谷川雅一
竹安巧
土屋直树
长谷直树
高桥克史
上村孝
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Publication of CN1173169A publication Critical patent/CN1173169A/zh
Application granted granted Critical
Publication of CN1081623C publication Critical patent/CN1081623C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • C07C235/38—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN96191624A 1995-11-27 1996-11-26 苯衍生物 Expired - Fee Related CN1081623C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP307222/95 1995-11-27
JP30722295 1995-11-27
JP228367/96 1996-08-29
JP22836796 1996-08-29

Publications (2)

Publication Number Publication Date
CN1173169A CN1173169A (zh) 1998-02-11
CN1081623C true CN1081623C (zh) 2002-03-27

Family

ID=26528211

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96191624A Expired - Fee Related CN1081623C (zh) 1995-11-27 1996-11-26 苯衍生物

Country Status (12)

Country Link
US (1) US5808144A (OSRAM)
EP (1) EP0806412B1 (OSRAM)
JP (1) JP3117466B2 (OSRAM)
KR (1) KR100309754B1 (OSRAM)
CN (1) CN1081623C (OSRAM)
AT (1) ATE191458T1 (OSRAM)
AU (1) AU703092B2 (OSRAM)
CA (1) CA2210579C (OSRAM)
DE (1) DE69607597T2 (OSRAM)
ES (1) ES2144786T3 (OSRAM)
TW (1) TW346483B (OSRAM)
WO (1) WO1997019910A1 (OSRAM)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649656B1 (en) * 1998-07-24 2003-11-18 Teijin Limited Anthranilic acid derivatives
US6627743B1 (en) * 1999-12-03 2003-09-30 Abbott Laboratories 6-O-methylerythromycin A crystal form III
AU2001234089B2 (en) * 2000-02-15 2005-08-11 Teijin Limited Cancer remedy comprising anthranilic acid derivative as active ingredient
GB0319124D0 (en) * 2003-08-14 2003-09-17 Smithkline Beecham Corp Chemical compounds
WO2020252195A1 (en) * 2019-06-11 2020-12-17 The Wistar Institute Of Anatomy And Biology Telomerase reverse transcriptase degraders and methods of use thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015043A1 (fr) * 1992-01-24 1993-08-05 Yoshitomi Pharmaceutical Industries, Ltd. Compose arylalkananilide et utilisation pharmaceutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE736787A (fr) * 1968-08-02 1970-01-30 Roussel Uclaf Dérivés de l'acide anthranilique et procédé de préparation
JPS60116657A (ja) * 1983-11-30 1985-06-24 Ono Pharmaceut Co Ltd アニリン誘導体
US5783593A (en) * 1993-11-04 1998-07-21 Abbott Laboratories Inhibitors of squalene synthetase and protein farnesyltransferase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015043A1 (fr) * 1992-01-24 1993-08-05 Yoshitomi Pharmaceutical Industries, Ltd. Compose arylalkananilide et utilisation pharmaceutique

Also Published As

Publication number Publication date
EP0806412A4 (OSRAM) 1997-11-12
ATE191458T1 (de) 2000-04-15
TW346483B (en) 1998-12-01
US5808144A (en) 1998-09-15
KR19980701699A (ko) 1998-06-25
DE69607597D1 (de) 2000-05-11
WO1997019910A1 (en) 1997-06-05
JP3117466B2 (ja) 2000-12-11
EP0806412B1 (en) 2000-04-05
CA2210579A1 (en) 1997-06-05
EP0806412A1 (en) 1997-11-12
ES2144786T3 (es) 2000-06-16
CN1173169A (zh) 1998-02-11
DE69607597T2 (de) 2000-08-24
AU703092B2 (en) 1999-03-18
KR100309754B1 (ko) 2002-05-30
CA2210579C (en) 2003-03-11
AU7590296A (en) 1997-06-19

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Granted publication date: 20020327