CN108096440A - A kind of Chinese medicine composition with multiple detoxicating functions and preparation method thereof - Google Patents

A kind of Chinese medicine composition with multiple detoxicating functions and preparation method thereof Download PDF

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CN108096440A
CN108096440A CN201711479033.9A CN201711479033A CN108096440A CN 108096440 A CN108096440 A CN 108096440A CN 201711479033 A CN201711479033 A CN 201711479033A CN 108096440 A CN108096440 A CN 108096440A
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chinese medicine
medicine composition
dandelion
root
detoxicating functions
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缪荣明
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8965Asparagus, e.g. garden asparagus or asparagus fern
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The present invention provides a kind of Chinese medicine compositions with multiple detoxicating functions, are prepared by following Chinese medicine material:Paris polyphylla, Herba Euphorbiae Humifusae, sun plant, ink morning lotus, dandelion, the root of Dahurain angelica, asparagus fern.Composite antidote is made in above-mentioned Chinese medicine active compound by the present invention, has remarkable result to snakebite and bugbite, furunculosis carbuncle swells, abscess of throat and organic solvent acute poisoning.Convenient material drawing of the present invention, method that is cheap, taking and prepare is simple, greatly alleviates the financial burden of patient, easily and efficiently solves the phenomenon that causing to save poisoning treatment in time due to physical features is remote.

Description

A kind of Chinese medicine composition with multiple detoxicating functions and preparation method thereof
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, and in particular to a kind of Chinese medicine composition with multiple detoxicating functions and Its preparation method.
Background technology
With going deep into for medical research, the pharmacological action of antipyretic and antidotal type Chinese medicine is come out by extensive excavation, and in clinic Irreplaceable role is played in.Clinically the common Chinese medicine with antipyretic and antidote functions mainly has Fructus Forsythiae, gold and silver Flower, wild chrysanthemum, Radix Isatidis, oldenlandia diffusa, purslane and dandelion etc., these Chinese medicines have extremely wide in clinical treatment Application value, be suitable for the treatment of the diseases such as warm heat disease, abscess of throat, scald, snakebite and bugbite.
Detoxification Chinese traditional medicine at present on the market is various, it is necessary to be selected according to specific intoxication conditions in actual application Select detoxification Chinese traditional medicine.When in complicated wild environment, if poisoning is difficult to find effective detoxification Chinese traditional medicine, therefore, have The Chinese medicine composition of a variety of detoxicating functions seems particularly important.
The content of the invention
The object of the present invention is to provide a kind of Chinese medicine compositions with multiple detoxicating functions and preparation method thereof.
A kind of Chinese medicine composition with multiple detoxicating functions, is prepared by following Chinese medicine material:Paris polyphylla, Herba Euphorbiae Humifusae, Sun plant, ink morning lotus, dandelion, the root of Dahurain angelica, asparagus fern.
Further, the dosage of the Chinese medicine material is respectively:Paris polyphylla 2-4g, Herba Euphorbiae Humifusae 3-6g, sun plant 1-5g, Mo Zao Lotus 1-4g, dandelion 4-8g, root of Dahurain angelica 5-10g, asparagus fern 4-10g.
Further, the dosage of the Chinese medicine material is respectively:Paris polyphylla 3g, Herba Euphorbiae Humifusae 5g, sun plant 3g, ink morning lotus 2g, Dandelion 6g, root of Dahurain angelica 8g, asparagus fern 7g.
Paris polyphylla is liliaceous plant Yunnan Rhizoma Paridis or the dry rhizome of paris polyphylla.Its bitter, cold nature;It is slightly poisonous. There is clearing heat and detoxicating a, swelling and pain relieving, the effect of cool liver is calmed the frightened, be usually used in furunculosis carbuncle swells, abscess of throat, snakebite and bugbite, the pain of injury caused by falling and tumbling, Convulsion.
Herba Euphorbiae Humifusae is a kind of Chinese medicine, is harvested in summer, two season of autumn, removes impurity, dry.It can be clearing heat and detoxicating;Dampness removing moves back It is yellow;Promoting blood circulation and hemostasis.Main dysentery, diarrhea, jaundice;Hemoptysis;It spits blood;Hematuria;It has blood in stool;Uterine bleeding;Agalactia;Treating swelling and pain by traumatic injury and heat toxin Sore etc..
Sun plant all herbal medicine has the function of clearing heat and detoxicating, promoting blood circulation, swelling and pain relieving, anticancer etc..It is cold in nature sour, entirely Grass is containing ingredients such as multivitamin, trace element and amino acid.There are removing pattogenic heat from the blood and toxic material from the body, removing blood stasis and analgesics, detumescence and the work(of clearing heat and promoting diuresis Effect.
Black morning lotus, nourishing liver and kidney, cooling blood and hemostasis.For tooth mobility, poliosis, dizziness and tinnitus, soreness and weakness of waist and knees, the deficiency of Yin Blood-head, haematemesis, bleeding from five sense organs or subcutaneous tissue, hematuria, bloody flux, metrostaxis, traumatic hemorrhage.
In dandelion plant containing a variety of health-nutritions such as taraxol, taraxacin, choline, organic acid, synanthrin into Point.Nature and flavor are sweet, slight bitter, tremble with fear.Return liver, stomach.There are diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogic and other effects.Control heat toxin, carbuncle swells, sore, interior Carbuncle, red eye, swell pain, damp and hot, jaundice, the puckery pain of dribbling urination, furuncle swelling toxin, acute mastitis, scrofula, toothache, hot eyes, pharyngalgia, lung carbuncle, intestines Carbuncle, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis, scrofula, boil poisonous soreness.
The root of Dahurain angelica, master enter positive bright, awakening consciousness, are apt to wind-expelling pain-stopping.In the excited medulla oblongata respiratory center of root of Dahurain angelica element energy, vasomotion Pivot and vagus nerve can make breathing enhancing, blood pressure rising, pulse slack-off.
Asparagus fern be liliaceous plant lucid asparagus Asparaguscochinchinensis (Lour.) Merr. root tuber also known as Lucid asparagus.It is cold in nature, sweet in flavor, slight bitter.With replenishing the vital essence and removing heat, the effect of moistening lung nourshing kidney.For controlling fever due to yin deficiency, cough is spitted blood, lung Carbuncle, abscess of throat are quenched one's thirst, the illnesss such as constipation.Containing asparagine, B-sitosterol, steroid saponin, mucilaginous substance, furfural spread out lucid asparagus The ingredients such as biology.It is demonstrated experimentally that lucid asparagus bites function with the presence of hemocytes increasing, enhancing reticuloendothelial system tongue and extends antibody The effect of time.
Composite antidote is made in above-mentioned Chinese medicine active compound, acute to snakebite and bugbite, furunculosis carbuncle swells, abscess of throat and organic solvent Poisoning has remarkable result.Convenient material drawing of the present invention, method that is cheap, taking and prepare is simple, greatly alleviates trouble The financial burden of person easily and efficiently solves the phenomenon that causing to save poisoning treatment in time due to physical features is remote.
The preparation method of the above-mentioned Chinese medicine composition with multiple detoxicating functions, comprises the following steps:
Step 1, sun plant cleaned, dry, crush for use;
Step 2, by dandelion, the root of Dahurain angelica, asparagus fern, add water to cook three times, collecting decoction, filter, filtrate is condensed into 80 DEG C 5 ° The clear cream of Be, when precipitation 24 is small, leaching supernatant obtains mixing clear cream after concentration;
Step 3, Paris polyphylla, Herba Euphorbiae Humifusae, the early lotus of ink are crushed, is packed into percolate pot, adds in 90% ethanol as solvent, oozed It filters, collects liquid of just filtering, continue diacolation and collect continuous liquid of filtering, merge after concentration with liquid of just filtering, obtain percolate;
Step 4, sun plant fine powder, mixing clear cream are added in percolate, it is dry, obtain Chinese medicine composition.
Further, in step 2 dosage of water be dandelion, the root of Dahurain angelica, 5-10 times of asparagus fern total weight.
Further, diacolation speed is 15-50mL/min in step 3.
Further, it is dry for vacuum drying in step 4.
The Chinese medicine composition of the present invention have Toxin-Vanquishing is anti-inflammatory, clearing heat and promoting fluid, it is clear it is upper mend under, clearing heat and detoxicating, removing dampness through diuresis and removing jaundice, work The effect of blood stops blooding, can be widely used for snakebite and bugbite, furunculosis carbuncle swells, abscess of throat and organic solvent acute poisoning.
Specific embodiment
Technical scheme is described further With reference to embodiment.
Embodiment 1
A kind of Chinese medicine composition with multiple detoxicating functions, is prepared by following Chinese medicine material:Paris polyphylla, Herba Euphorbiae Humifusae, Sun plant, ink morning lotus, dandelion, the root of Dahurain angelica, asparagus fern.The dosage of the Chinese medicine material is respectively:Paris polyphylla 2g, Herba Euphorbiae Humifusae 3g, half Lotus 1g, ink morning lotus 1g, dandelion 4g, root of Dahurain angelica 5g, asparagus fern 4g.
The preparation method of the above-mentioned Chinese medicine composition with multiple detoxicating functions, comprises the following steps:
Step 1, sun plant cleaned, dry, crush for use;
Step 2, by dandelion, the root of Dahurain angelica, asparagus fern, add water to cook three times, the dosage of water is dandelion, the root of Dahurain angelica, asparagus fern gross weight 5 times of amount, collecting decoction, filtration, filtrate is condensed into the clear cream of 80 DEG C of 5 ° of Be, when precipitation 24 is small, leaching supernatant, after concentration To mixing clear cream;
Step 3, Paris polyphylla, Herba Euphorbiae Humifusae, the early lotus of ink are crushed, is packed into percolate pot, adds in 90% ethanol as solvent, oozed It filters, diacolation speed is 15mL/min, collects liquid of just filtering, and continues diacolation and collects continuous liquid of filtering, merges after concentration with liquid of just filtering, obtain diacolation Liquid;
Step 4, sun plant fine powder, mixing clear cream are added in percolate, is dried in vacuo, obtains Chinese medicine composition.
Embodiment 2
A kind of Chinese medicine composition with multiple detoxicating functions, is prepared by following Chinese medicine material:Paris polyphylla, Herba Euphorbiae Humifusae, Sun plant, ink morning lotus, dandelion, the root of Dahurain angelica, asparagus fern.The dosage of the Chinese medicine material is respectively:Paris polyphylla 3g, Herba Euphorbiae Humifusae 5g, half Lotus 3g, ink morning lotus 2g, dandelion 6g, root of Dahurain angelica 8g, asparagus fern 7g.
The preparation method of the above-mentioned Chinese medicine composition with multiple detoxicating functions, comprises the following steps:
Step 1, sun plant cleaned, dry, crush for use;
Step 2, by dandelion, the root of Dahurain angelica, asparagus fern, add water to cook three times, the dosage of water is dandelion, the root of Dahurain angelica, asparagus fern gross weight 5 times of amount, collecting decoction, filtration, filtrate is condensed into the clear cream of 80 DEG C of 5 ° of Be, when precipitation 24 is small, leaching supernatant, after concentration To mixing clear cream;
Step 3, Paris polyphylla, Herba Euphorbiae Humifusae, the early lotus of ink are crushed, is packed into percolate pot, adds in 90% ethanol as solvent, oozed It filters, diacolation speed is 15mL/min, collects liquid of just filtering, and continues diacolation and collects continuous liquid of filtering, merges after concentration with liquid of just filtering, obtain diacolation Liquid;
Step 4, sun plant fine powder, mixing clear cream are added in percolate, is dried in vacuo, obtains Chinese medicine composition.
Embodiment 3
A kind of Chinese medicine composition with multiple detoxicating functions, is prepared by following Chinese medicine material:Paris polyphylla, Herba Euphorbiae Humifusae, Sun plant, ink morning lotus, dandelion, the root of Dahurain angelica, asparagus fern.The dosage of the Chinese medicine material is respectively:Paris polyphylla 4g, Herba Euphorbiae Humifusae 6g, half Lotus 5g, ink morning lotus 4g, dandelion 8g, root of Dahurain angelica 10g, asparagus fern 10g.
The preparation method of the above-mentioned Chinese medicine composition with multiple detoxicating functions, comprises the following steps:
Step 1, sun plant cleaned, dry, crush for use;
Step 2, by dandelion, the root of Dahurain angelica, asparagus fern, add water to cook three times, the dosage of water is dandelion, the root of Dahurain angelica, asparagus fern gross weight 5 times of amount, collecting decoction, filtration, filtrate is condensed into the clear cream of 80 DEG C of 5 ° of Be, when precipitation 24 is small, leaching supernatant, after concentration To mixing clear cream;
Step 3, Paris polyphylla, Herba Euphorbiae Humifusae, the early lotus of ink are crushed, is packed into percolate pot, adds in 90% ethanol as solvent, oozed It filters, diacolation speed is 15mL/min, collects liquid of just filtering, and continues diacolation and collects continuous liquid of filtering, merges after concentration with liquid of just filtering, obtain diacolation Liquid;
Step 4, sun plant fine powder, mixing clear cream are added in percolate, is dried in vacuo, obtains Chinese medicine composition.
Comparative example 1
The present embodiment and differing only in for embodiment 2 do not add Paris polyphylla and dandelion, other components and dosage and implementation Example 2 is identical.
Comparative example 2
The present embodiment does not add black early lotus and Herba Euphorbiae Humifusae, other components and dosage and reality with differing only in for embodiment 2 It is identical to apply example 2.
Embodiment 4 has shadow of the Chinese medicine composition to the rat toes swelling as caused by bite by mosquitos of multiple detoxicating functions It rings
Wistar rats, 70, weight 160-200g is provided by Institute of Zoology, Academia Sinica's animal center.Rat It is randomly divided into 1. blank control groups (physiological saline);2. positive controls (aspirin);3. 1 Chinese medicine composition of embodiment, 200mg crude drugs/kg);4. 2 Chinese medicine composition 200mg crude drugs of embodiment/kg);5. 3 Chinese medicine composition of embodiment, 200mg crude drugs/ kg;6. 1 200mg crude drugs of reference examples/kg.Every group 10.Each group gives 1 times/day of the by reagent of corresponding content, continuous gavage administration 7 My god.Formic acid (simulating bite by mosquitos, 0.1ml, 1%w/v with formic acid) is subcutaneously injected into every rat by last dose after 30 minutes Right hallux.Formic acid injection before and injection after 1,2,3,4,5 and 6 it is small when respectively with YLS-7B type toes capacity measurers Rat Right metapedes volume is measured, the difference of volume the results are shown in Table 1 as swelling before and after causing inflammation using each mouse.
Table 1
From experimental result as it can be seen that Chinese medicine composition provided by the invention has preferably for swelling caused by bite by mosquitos Anti-inflammatory effects, each substance synergistic effect, anti-inflammatory effects are more than aspirin medicine group in its composition.
5 Chinese medicine composition of embodiment is to the anti-inflammatory effects of the mice ear as caused by dimethylbenzene
The kunming mice of Zhejiang Province experimental center breeding selects healthy adult male mice 70, weight 18-22g. mouse with Machine is divided into 1. blank control groups (physiological saline);2. positive controls (aspirin);3. embodiment 1,200mg crude drugs/kg;4. Embodiment 2,200mg crude drugs/kg;5. embodiment 3,200mg crude drugs/kg;6. comparative example 1,200mg crude drugs/kg;7. comparative example 2, 200mg crude drugs/kg;Every group 10.Each group gives 1 times/day of the by reagent of corresponding content, and continuous gavage is administered 7 days.By dimethylbenzene 20 μ l are added dropwise in every mouse right ear lateral surface auricle center, by its free diffusing, 1 it is small when after, mouse cervical dislocation is put to death, is cut Mouse ears lay auricle in two ear same areas with 9mm diameters card punch and weigh.Swelling value by same mouse right ear with The weight difference of left ear determines.Anti-inflammatory rate is calculated by equation below:Anti-inflammatory rate (%)=(1-x/a) × 100%, wherein x are mouse Ear swelling value, a are blank control group (physiological saline) mice ear value, the results are shown in Table 2.
Influence of the table 2. to the mice ear as caused by dimethylbenzene
Group Dosage (mg/kg) Mouse number Swelling value (mg) Anti-inflammatory rate
Blank control group - 10 15.08 /
Aspirin 200 10 8.62 42.84%
Embodiment 1 200 10 9.89 34.42%
Embodiment 2 200 10 8.47 43.83%
Embodiment 3 200 10 10.22 32.23%
Comparative example 1 200 10 12.10 19.76%
Comparative example 2 200 10 13.36 11.41%
Composite antidote is made in above-mentioned Chinese medicine active compound by the present invention, to snakebite and bugbite, furunculosis carbuncle swells, abscess of throat and organic Solvent acute poisoning has remarkable result.Convenient material drawing of the present invention, method that is cheap, taking and prepare is simple, greatly The financial burden of patient is alleviated, easily and efficiently solving causes that poisoning treatment cannot be saved in time due to physical features is remote Phenomenon.

Claims (7)

1. a kind of Chinese medicine composition with multiple detoxicating functions, it is characterised in that:It is prepared by following Chinese medicine material:Weight Building, Herba Euphorbiae Humifusae, sun plant, ink morning lotus, dandelion, the root of Dahurain angelica, asparagus fern.
2. the Chinese medicine composition according to claim 1 with multiple detoxicating functions, it is characterised in that:The Chinese medicine material Dosage be respectively:Paris polyphylla 2-4g, Herba Euphorbiae Humifusae 3-6g, sun plant 1-5g, ink morning lotus 1-4g, dandelion 4-8g, root of Dahurain angelica 5-10g, Asparagus fern 4-10g.
3. the Chinese medicine composition according to claim 1 with multiple detoxicating functions, it is characterised in that:The Chinese medicine material Dosage be respectively:Paris polyphylla 3g, Herba Euphorbiae Humifusae 5g, sun plant 3g, ink morning lotus 2g, dandelion 6g, root of Dahurain angelica 8g, asparagus fern 7g.
4. the preparation method of the Chinese medicine composition described in claim 1 with multiple detoxicating functions, it is characterised in that:Including with Lower step:
Step 1, sun plant cleaned, dry, crush for use;
Step 2, by dandelion, the root of Dahurain angelica, asparagus fern, add water to cook three times, collecting decoction, filter, filtrate is condensed into 80 DEG C of 5 ° of Be's Clear cream, when precipitation 24 is small, leaching supernatant obtains mixing clear cream after concentration;
Step 3, Paris polyphylla, Herba Euphorbiae Humifusae, the early lotus of ink are crushed, is packed into percolate pot, adds in 90% ethanol as solvent, carry out diacolation, receive The first liquid of filtering of collection continues diacolation and collects continuous liquid of filtering, merges after concentration with liquid of just filtering, obtain percolate;
Step 4, sun plant fine powder, mixing clear cream are added in percolate, it is dry, obtain Chinese medicine composition.
5. the preparation method of the Chinese medicine composition according to claim 4 with multiple detoxicating functions, it is characterised in that:Step In rapid 2 the dosage of water be dandelion, the root of Dahurain angelica, 5-10 times of asparagus fern total weight.
6. the preparation method of the Chinese medicine composition according to claim 4 with multiple detoxicating functions, it is characterised in that:Step Diacolation speed is 15-50mL/min in rapid 3.
7. the preparation method of the Chinese medicine composition according to claim 4 with multiple detoxicating functions, it is characterised in that:Step It is dry for vacuum drying in rapid 4.
CN201711479033.9A 2017-12-29 2017-12-29 A kind of Chinese medicine composition with multiple detoxicating functions and preparation method thereof Pending CN108096440A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101091769A (en) * 2007-07-20 2007-12-26 李文良 Medicine for treating and preventing esophagus cancer and gastric cancer, and preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101091769A (en) * 2007-07-20 2007-12-26 李文良 Medicine for treating and preventing esophagus cancer and gastric cancer, and preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
张仕益等: "五味消毒饮和仙方活命饮加减治疗痤疮52例", 《云南中医中药杂志》 *
李晓健等: "蝮蛇咬伤致MSOF的临床特点及治疗", 《蛇志》 *

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