CN107922834A - 用具有aie特性的荧光光稳定线粒体特异生物探针实时监测线粒体自噬过程 - Google Patents
用具有aie特性的荧光光稳定线粒体特异生物探针实时监测线粒体自噬过程 Download PDFInfo
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- CN107922834A CN107922834A CN201680023064.0A CN201680023064A CN107922834A CN 107922834 A CN107922834 A CN 107922834A CN 201680023064 A CN201680023064 A CN 201680023064A CN 107922834 A CN107922834 A CN 107922834A
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- bioprobe
- aie
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/0805—Compounds with Si-C or Si-Si linkages comprising only Si, C or H atoms
- C07F7/0807—Compounds with Si-C or Si-Si linkages comprising only Si, C or H atoms comprising Si as a ring atom
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
- C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1003—Carbocyclic compounds
- C09K2211/1007—Non-condensed systems
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1018—Heterocyclic compounds
- C09K2211/1025—Heterocyclic compounds characterised by ligands
- C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
- C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
- C09K2211/10—Non-macromolecular compounds
- C09K2211/1018—Heterocyclic compounds
- C09K2211/1025—Heterocyclic compounds characterised by ligands
- C09K2211/1096—Heterocyclic compounds characterised by ligands containing other heteroatoms
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
Description
Claims (13)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201562178512P | 2015-04-13 | 2015-04-13 | |
US62/178,512 | 2015-04-13 | ||
PCT/CN2016/074337 WO2016165487A1 (en) | 2015-04-13 | 2016-02-23 | Real-time monitoring mitophagy process by fluorescent photostable mitochondrial specific bioprobe with aie characteristics |
Publications (2)
Publication Number | Publication Date |
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CN107922834A true CN107922834A (zh) | 2018-04-17 |
CN107922834B CN107922834B (zh) | 2020-04-14 |
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CN201680023064.0A Active CN107922834B (zh) | 2015-04-13 | 2016-02-23 | 用具有aie特性的荧光光稳定线粒体特异生物探针实时监测线粒体自噬过程 |
Country Status (2)
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CN (1) | CN107922834B (zh) |
WO (1) | WO2016165487A1 (zh) |
Cited By (7)
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CN108530345A (zh) * | 2018-04-28 | 2018-09-14 | 陕西师范大学 | 一种具有聚集诱导发光特性的鎓盐化合物及其制备方法和应用 |
CN111596053A (zh) * | 2019-02-21 | 2020-08-28 | 南方医科大学南方医院 | Tpn分子在制备循环肿瘤细胞检测试剂中的用途及检测试剂和试剂盒 |
CN111690005A (zh) * | 2020-06-27 | 2020-09-22 | 北京化工大学 | 一种具有线粒体靶向和聚集诱导发光效应的传感阵列及其细胞辨别的应用 |
CN112321492A (zh) * | 2020-10-23 | 2021-02-05 | 山西大学 | 监测线粒体自噬的荧光粘度探针及制备和应用 |
CN112920095A (zh) * | 2021-01-29 | 2021-06-08 | 深圳大学 | 新型聚集诱导发光内质网荧光探针及其制备方法与应用 |
CN114106095A (zh) * | 2021-11-11 | 2022-03-01 | 华南理工大学 | 基于聚集诱导发光原理的细胞自噬检测分子探针及其制备方法和应用 |
CN114957313A (zh) * | 2022-04-29 | 2022-08-30 | 山东大学 | 硅氧烷桥联的四苯乙烯衍生物、其制备方法及其用途 |
Families Citing this family (4)
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US11253592B2 (en) * | 2017-10-24 | 2022-02-22 | The Hong Kong University Of Science And Technology | Water-soluble compounds with aggregation-induced emission characteristics |
WO2020108479A1 (en) * | 2018-11-26 | 2020-06-04 | The Hong Kong University Of Science And Technology | Probes for selective thiol detection |
CN113848197B (zh) * | 2021-10-26 | 2023-10-13 | 常熟理工学院 | 一种荧光探针的用途 |
WO2024119373A1 (zh) * | 2022-12-06 | 2024-06-13 | 深圳先进技术研究院 | 聚集诱导发光工程线粒体在制备治疗癌症的药物中的应用 |
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- 2016-02-23 WO PCT/CN2016/074337 patent/WO2016165487A1/en active Application Filing
- 2016-02-23 CN CN201680023064.0A patent/CN107922834B/zh active Active
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CN114106095A (zh) * | 2021-11-11 | 2022-03-01 | 华南理工大学 | 基于聚集诱导发光原理的细胞自噬检测分子探针及其制备方法和应用 |
CN114106095B (zh) * | 2021-11-11 | 2023-06-09 | 华南理工大学 | 基于聚集诱导发光原理的细胞自噬检测分子探针及其制备方法和应用 |
CN114957313A (zh) * | 2022-04-29 | 2022-08-30 | 山东大学 | 硅氧烷桥联的四苯乙烯衍生物、其制备方法及其用途 |
CN114957313B (zh) * | 2022-04-29 | 2024-04-30 | 山东大学 | 硅氧烷桥联的四苯乙烯衍生物、其制备方法及其用途 |
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