CN107922459B - 粘附性肽及其用途 - Google Patents
粘附性肽及其用途 Download PDFInfo
- Publication number
- CN107922459B CN107922459B CN201680028082.8A CN201680028082A CN107922459B CN 107922459 B CN107922459 B CN 107922459B CN 201680028082 A CN201680028082 A CN 201680028082A CN 107922459 B CN107922459 B CN 107922459B
- Authority
- CN
- China
- Prior art keywords
- cells
- peptide
- peptides
- adhesion
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
- C07K14/43586—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects from silkworms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09J—ADHESIVES; NON-MECHANICAL ASPECTS OF ADHESIVE PROCESSES IN GENERAL; ADHESIVE PROCESSES NOT PROVIDED FOR ELSEWHERE; USE OF MATERIALS AS ADHESIVES
- C09J189/00—Adhesives based on proteins; Adhesives based on derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2539/00—Supports and/or coatings for cell culture characterised by properties
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Plant Pathology (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Surgery (AREA)
- Developmental Biology & Embryology (AREA)
- Gynecology & Obstetrics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020150042167A KR101794401B1 (ko) | 2015-03-26 | 2015-03-26 | 접착성 펩타이드 및 그 용도 |
| KR10-2015-0042167 | 2015-03-26 | ||
| PCT/KR2016/002864 WO2016153256A1 (ko) | 2015-03-26 | 2016-03-22 | 접착성 펩타이드 및 그 용도 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107922459A CN107922459A (zh) | 2018-04-17 |
| CN107922459B true CN107922459B (zh) | 2021-06-25 |
Family
ID=56977649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680028082.8A Expired - Fee Related CN107922459B (zh) | 2015-03-26 | 2016-03-22 | 粘附性肽及其用途 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10857258B2 (enExample) |
| EP (1) | EP3279209A4 (enExample) |
| JP (1) | JP6856618B2 (enExample) |
| KR (1) | KR101794401B1 (enExample) |
| CN (1) | CN107922459B (enExample) |
| WO (1) | WO2016153256A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9801972B2 (en) | 2014-10-02 | 2017-10-31 | Postech Academy-Industry Foundation | Mussel-inspired bioactive surface coating composition generating silica nanoparticles |
| KR20160040063A (ko) * | 2014-10-02 | 2016-04-12 | 포항공과대학교 산학협력단 | 생활성 융합단백질 및 이를 포함하는 실리카 나노입자를 포함하는 표면 코팅제 |
| KR101865451B1 (ko) * | 2015-08-26 | 2018-07-13 | 윤원준 | 무기물 표면 접착 또는 코팅용 단백질 접착제 |
| WO2018038582A1 (ko) * | 2016-08-26 | 2018-03-01 | 윤원준 | 골재생 또는 골형성 촉진용 펩타이드 및 그 용도 |
| KR102000507B1 (ko) * | 2016-09-12 | 2019-07-16 | (주)세원생명공학 | 피더세포 없이 줄기세포 배양이 가능한 배양 조성물 및 방법 |
| KR102010871B1 (ko) * | 2016-09-13 | 2019-10-21 | (주)세원생명공학 | 세포접착용 조성물 및 방법 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101163496A (zh) * | 2005-02-25 | 2008-04-16 | 犹他大学研究基金会 | 促进内皮细胞的粘附或迁移的弹性蛋白原 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0625290A (ja) * | 1992-07-10 | 1994-02-01 | Sumitomo Pharmaceut Co Ltd | 細胞接着活性ペプチド |
| JP2002518135A (ja) | 1998-06-23 | 2002-06-25 | サージカル シーランツ, インコーポレイテッド | 生体接着性の外科用シーラントおよび移植可能デバイスのためのカルボジイミド架橋アルブミン |
| US20020022588A1 (en) | 1998-06-23 | 2002-02-21 | James Wilkie | Methods and compositions for sealing tissue leaks |
| KR100885071B1 (ko) * | 2002-05-14 | 2009-02-25 | 재단법인서울대학교산학협력재단 | 세포에 부착하는 올리고펩타이드 |
| JP3906924B2 (ja) * | 2003-02-28 | 2007-04-18 | 独立行政法人農業生物資源研究所 | 絹タンパクから細胞生育ペプチドの抽出と利用 |
| KR20060105054A (ko) * | 2004-01-13 | 2006-10-09 | 도레이 가부시끼가이샤 | 거미줄 단백질을 포함하는 견사 및 상기 견사를 생산하는누에 |
| JP2007252327A (ja) * | 2006-03-24 | 2007-10-04 | Toray Ind Inc | 細胞接着性絹糸及びその製造方法 |
| WO2009097540A1 (en) * | 2008-02-01 | 2009-08-06 | Entogenetics, Inc. | Methods, compositions, and systems for production of recombinant spider silk polypeptides |
| KR101094445B1 (ko) * | 2009-05-13 | 2011-12-15 | 한국과학기술연구원 | 줄기세포에 대한 접착활성을 갖는 섬유아세포 성장인자의 재조합 단백질 및 이를 이용한 줄기세포의 배양방법 |
| KR101209233B1 (ko) * | 2011-02-21 | 2012-12-06 | 서울대학교산학협력단 | 피브린 결합능을 가진 생리활성 펩타이드가 함유된 피브린 수화젤 |
| KR101865451B1 (ko) * | 2015-08-26 | 2018-07-13 | 윤원준 | 무기물 표면 접착 또는 코팅용 단백질 접착제 |
-
2015
- 2015-03-26 KR KR1020150042167A patent/KR101794401B1/ko not_active Expired - Fee Related
-
2016
- 2016-03-22 CN CN201680028082.8A patent/CN107922459B/zh not_active Expired - Fee Related
- 2016-03-22 WO PCT/KR2016/002864 patent/WO2016153256A1/ko not_active Ceased
- 2016-03-22 JP JP2018501837A patent/JP6856618B2/ja not_active Expired - Fee Related
- 2016-03-22 EP EP16769074.2A patent/EP3279209A4/en not_active Withdrawn
-
2017
- 2017-09-25 US US15/714,357 patent/US10857258B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101163496A (zh) * | 2005-02-25 | 2008-04-16 | 犹他大学研究基金会 | 促进内皮细胞的粘附或迁移的弹性蛋白原 |
Non-Patent Citations (1)
| Title |
|---|
| fibroin heavy chain, partial [Bombyx mori],ACCESSION NO.:ABE77387.1;Wang,S.等;《GenBank Database》;20060423;1 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US10857258B2 (en) | 2020-12-08 |
| EP3279209A1 (en) | 2018-02-07 |
| EP3279209A4 (en) | 2019-01-02 |
| KR20160115115A (ko) | 2016-10-06 |
| WO2016153256A1 (ko) | 2016-09-29 |
| JP2018511344A (ja) | 2018-04-26 |
| JP6856618B2 (ja) | 2021-04-07 |
| CN107922459A (zh) | 2018-04-17 |
| US20180085488A1 (en) | 2018-03-29 |
| KR101794401B1 (ko) | 2017-11-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107922459B (zh) | 粘附性肽及其用途 | |
| Alshehri et al. | Scaffolds from self-assembling tetrapeptides support 3D spreading, osteogenic differentiation, and angiogenesis of mesenchymal stem cells | |
| Xu et al. | A carboxymethyl chitosan and peptide-decorated polyetheretherketone ternary biocomposite with enhanced antibacterial activity and osseointegration as orthopedic/dental implants | |
| Sagnella et al. | Human endothelial cell interaction with biomimetic surfactant polymers containing peptide ligands from the heparin binding domain of fibronectin | |
| Xie et al. | Enhanced proliferation and differentiation of neural stem cells grown on PHA films coated with recombinant fusion proteins | |
| Yaylaci et al. | Chondrogenic differentiation of mesenchymal stem cells on glycosaminoglycan-mimetic peptide nanofibers | |
| CN105960411A (zh) | 自组装肽、肽模拟物和肽缀合物作为构件用于生物制造和打印 | |
| Lee et al. | Injectable gel with synthetic collagen-binding peptide for enhanced osteogenesis in vitro and in vivo | |
| Zhao et al. | Construction of multifunctional coating with cationic amino acid-coupled peptides for osseointegration of implants | |
| Chen et al. | Osteogenesis regulation of mesenchymal stem cells via autophagy induced by silica–titanium composite surfaces with different mechanical moduli | |
| US10851132B2 (en) | Protein based adhesive composition and method | |
| Zhang et al. | Compatibility of neural stem cells with functionalized self-assembling peptide scaffold in vitro | |
| JP2021514676A (ja) | 幹細胞の拡大および分化 | |
| JP2010088933A (ja) | ペプチド被覆インプラントおよびその調製方法 | |
| Pugliese et al. | Functionalization of self-assembling peptides for neural tissue engineering | |
| KR101794482B1 (ko) | 생체 또는 비생체 접착성 펩타이드 및 그 용도 | |
| KR102010871B1 (ko) | 세포접착용 조성물 및 방법 | |
| JP5236313B2 (ja) | 細胞の形態及び機能の調節活性を有するアリールスルファターゼタンパク質 | |
| EP4253527A1 (en) | Coated article for culturing primary cells and stem cells and method for preparing the same | |
| US20250207087A1 (en) | Extracellular matrix-containing composition and method for producing same, and three-dimensional tissue construct and method for producing same | |
| EP4148133A1 (en) | Chimeric protein containing fibrinogen fragment and laminin fragment, and use thereof | |
| WO2014110389A1 (en) | Hybrid matrix | |
| JP2020172470A (ja) | 人工コラーゲン様ペプチドを用いた細胞培養足場材 | |
| Dağdaş | Characterization and corneal tissue engineering application of peptide amphiphiles |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20180810 Address after: Seoul, South Kerean Applicant after: World aid life engineering Address before: Seoul, South Kerean Applicant before: Yin Yuanjun |
|
| TA01 | Transfer of patent application right | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20210625 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |