CN107912437A - A kind of bactericidal composition and its application containing pyraziflumid - Google Patents

A kind of bactericidal composition and its application containing pyraziflumid Download PDF

Info

Publication number
CN107912437A
CN107912437A CN201610885583.XA CN201610885583A CN107912437A CN 107912437 A CN107912437 A CN 107912437A CN 201610885583 A CN201610885583 A CN 201610885583A CN 107912437 A CN107912437 A CN 107912437A
Authority
CN
China
Prior art keywords
pyraziflumid
disease
agent
composition
bacterium azoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201610885583.XA
Other languages
Chinese (zh)
Inventor
任太军
梁旭东
胡欢欢
魏靖
王泰
曹明章
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Noposion Agrochemicals Co Ltd
Original Assignee
Shenzhen Noposion Agrochemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Noposion Agrochemicals Co Ltd filed Critical Shenzhen Noposion Agrochemicals Co Ltd
Priority to CN201610885583.XA priority Critical patent/CN107912437A/en
Publication of CN107912437A publication Critical patent/CN107912437A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N55/00—Biocides, pest repellants or attractants, or plant growth regulators, containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur

Abstract

The invention discloses a kind of bactericidal composition containing pyraziflumid, active ingredient in said composition is A and B, active components A is pyraziflumid, active ingredient B is a kind of triazole bactericidal agent, any one of triazole bactericidal agent in difenoconazole, propiconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, Tebuconazole, nitrile bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles and prothioconazoles, and the mass ratio of active components A and active ingredient B are 50：1~1：50.For the present composition available for the multiple diseases in prevention vegetables, fruit tree, flowers and other crops, the disease such as powdery mildew, scab particularly as caused by higher fungus, there is good prevention effect, has the characteristics that wide sterilization spectrum, dosage are low, synergistic effect is obvious.

Description

A kind of bactericidal composition and its application containing pyraziflumid
Technical field
The present invention relates to a kind of composition pesticide, more particularly to a kind of bactericidal composition containing pyraziflumid and its Application in crop disease, belongs to technical field of pesticide.
Background technology
Pyraziflumid (test code number NNF-0721) is the SDHI series bactericidal agents of Nihon Nihyaku Co., Ltd's exploitation, right Powdery mildew, scab, gray mold, sclerotiniose, ring spot on rice, fruits and vegetables etc. have good prevention effect, structure Formula is as follows：
In actual production, prevention pest and disease damage is easiest to generate the problem that resistance.Different cultivars component carries out compounding Prevent the very common method of resistance pest and disease damage.Heterogeneity is compounded, and is to judge certain compounding according to practical application effect Synergy, addition or antagonism.In most cases, the compounding effect of pesticide is all summation action, really there is synergy work Compounding is seldom, and the particularly particularly apparent compounding of synergistic effect is just less.
The content of the invention
It is an object of the invention to provide the composition and its application that a kind of synergistic effect is obvious, prevention spectrum is wide.
To reach goal of the invention, the technical solution adopted by the present invention is：
A kind of bactericidal composition, is A containing active ingredient in composition and active ingredient B, active components A are Pyraziflumid, active ingredient B are a kind of triazole bactericidal agent, and triazole bactericidal agent is selected from difenoconazole, propiconazole, fluorine Silicon azoles, epoxiconazole, triazolone, hexaconazole, Tebuconazole, nitrile bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles and rosickyite bacterium The mass ratio of any one in azoles, active components A and active ingredient B are 50：1~1：50, preferred mass ratio is 20：1~1： 20。
Disease of the present composition particularly suitable for preventing crops, the crops include cereal crops, beans Crop, oil crops, fibre crops, sugar crop, melon crop, fruits crop, dry fruit crop, root crop, flower Grass crop, medicinal crop, crop, green manure pasture crop.
The disease includes：Target spot, blight dis-ease, rust, ring spot, sclerotiniose, smut, full rot, root rot, Gray mold, damping-off, banded sclerotial blight, bakanae disease, droop, sclerotiniose, poliosis, downy mildew, samping off, brown spot, powdery mildew, Anthracnose, early blight, leaf mold, leaf spot, scab, tar spot, shot hole, epidemic disease, base rot disease, verticillium wilt, clubroot Etc. a variety of fungal diseases.
Insecticide-applying way can use spraying, pouring root, leaching root, soak seed, gets rid of and apply, spread fertilizer over the fields, ditch spread, spreading manuer in holes, prevention soil-borne disease Preferred ditch spread during evil, spread manuer in holes, the soil treatment such as pouring root or leaching root, seed soaking, seed pelleting processing.
The present composition can be used in mixed way with other compounds with weeding, bactericidal property, can also be with desinsection Agent, nematicide, protective agent, growth regulator, nutrient for plants or soil conditioner are used in mixed way.
The present composition compared with the existing technology, can at least produce following beneficial effect：
After 1. two kinds of active components compound according to the above ratio in composition, there is notable synergistic and lasting effect；
2. field dosage and times for spraying can be greatly decreased, production and application cost is reduced, it is dirty effectively to reduce environment Dye and pesticide residue, reduce the harm to beneficial organism；
3. expand fungicidal spectrum：To all kinds of true on crops after two kinds of active components is compounded in the ratio in composition Fungal disease can play the role of it is simultaneous control, and significant effect；
4. composition is made of the active ingredient of different mechanism of action, action site increase, is conducive to overcome and delay disease The drug-fast generation of bacterium.
Embodiment
For the object, technical solutions and advantages of the present invention are more clearly understood, with reference to embodiment in the present invention Appearance is described further, but the present invention is limited to absolutely not these examples.Specific embodiment is only used for explaining the present invention, is not used to limit The fixed present invention.Any modifications, equivalent replacements and improvementsmade within the spirit and principles of the invention, etc., should be included in Within protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be determined by the appended claims.
The present invention can be prepared into the formulation of suitable agricultural use with known method, and composition can be according to required prevention Crop, local environment condition, control method, the various factors such as cost accounting, by active ingredient and auxiliary agent and carrier (filler) Any one acceptable formulation in pesticides application is processed into together, and preferred dosage form is suspension seed-coating agent, granule, micro-capsule hang Floating agent, microemulsion, aqueous emulsion, suspending agent, wettable powder, water dispersible granules or missible oil.Adjuvant used, carrier and processing technology Using known component.In above-mentioned various formulations, in composition the gross mass percentage composition of effective active composition for 0.5%~ 85%, for example, when the mass percentage of pyraziflumid and difenoconazole are respectively 10%, 10%, gross mass hundred It is 20% to divide content.
First, preparation processing formulation Example
Embodiment 1：20%pyraziflumid difenoconazole suspending agent (pyraziflumid：Difenoconazole= 1：3)
It is made according to common process, wherein pyraziflumid 5g, difenoconazole 15g, sodium lignin sulfonate is (scattered Agent) 4g, lauryl sodium sulfate (wetting agent) 2g, ethylene glycol (antifreeze) 4g, bentonite (thickener) 0.15g, organic silicone (defoamer) 0.4g, deionized water are mended to 100g.
The part by weight of pyraziflumid and difenoconazole can be 20 in the present embodiment：1~1：Change between 20, Both mass percentages can change between 5%~80%, be also adjusted accordingly therewith using the proportioning of auxiliary agent, be formed New embodiment.
Difenoconazole can also be substituted for propiconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, Tebuconazole, nitrile Bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 2：51%pyraziflumid tetraconazole water dispersible granules (pyraziflumid：Tetraconazole= 1：50)
It is made according to common process, wherein pyraziflumid 1g, tetraconazole 50g, Negel (dispersant) 5g, sodium lignin sulfonate (dispersant) 7g, lauryl sodium sulfate (wetting agent) 2g, ammonium sulfate (disintegrant) 5g, lightweight carbonic acid Calcium (filler) complements to 100g.
The part by weight of pyraziflumid and tetraconazole can be 50 in the present embodiment：1~1：Change between 50, two The mass percentage of person can change between 1%~85%, be also adjusted accordingly therewith using the proportioning of auxiliary agent, be formed new Embodiment.
Tetraconazole can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, Tebuconazole, nitrile bacterium azoles, tricyclazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 3：42%pyraziflumid trazodone wettable powders (pyraziflumid：Triazolone=1：20)
It is made according to common process, wherein pyraziflumid 2g, triazolone 40g, lauryl sodium sulfate (wetting agent) 2g, sodium lignin sulfonate (dispersant) 3g, NNO (dispersant) 5g, kaolin complement to 100g.
The part by weight of pyraziflumid and triazolone can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 1%~85%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Triazolone can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, hexaconazole, Tebuconazole, nitrile Bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 4：6%pyraziflumid propiconazole microemulsions (pyraziflumid：Propiconazole=5：1)
It is made according to common process, wherein pyraziflumid 5g, propiconazole 1g, 1-methyl-2-pyrrolidinone (solvent) 10g, isopropanol (solvent) 5g, No. 500 (emulsifying agent) 5g of agriculture breast, No. 1601 (emulsifying agent) 5g of agriculture breast, deionized water complement to 100g。
The part by weight of pyraziflumid and propiconazole can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 1%~30%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Propiconazole can also be substituted for difenoconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, Tebuconazole, nitrile Bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 5：11%pyraziflumid epoxiconazole microcapsule suspending agents (pyraziflumid：Epoxiconazole=1：10)
It is made according to common process, wherein pyraziflumid 1g, epoxiconazole 10g, cyclohexanone (solvent) 1g, more isocyanides Acid esters (curing agent) 0.4g, ethylene glycol (antifreezing agent) 0.4g, Arabic gum (thickener) 1g, deionized water complement to 100g.
The part by weight of pyraziflumid and epoxiconazole can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 1%~60%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Epoxiconazole can also be substituted for difenoconazole, propiconazole, Flusilazole, triazolone, hexaconazole, Tebuconazole, nitrile Bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 6：22%pyraziflumid Flusilazole aqueous emulsions (pyraziflumid：Flusilazole=10：1)
It is made according to common process, wherein pyraziflumid 20g, Flusilazole 2g, calcium dodecyl benzene sulfonate (emulsification Agent) 2.1g, phenethyl phenol polyethenoxy ether (emulsifying agent) 1.5g, cyclohexanone (solvent) 10.1g, loose base ester vegetable oil (solvent) 10.2g, xanthans (thickener) 0.5g, deionized water complement to 100g.
The part by weight of pyraziflumid and Flusilazole can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 1%~60%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Flusilazole can also be substituted for difenoconazole, propiconazole, epoxiconazole, triazolone, hexaconazole, Tebuconazole, nitrile Bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 7：21%pyraziflumid prothioconazoles granules (pyraziflumid：Prothioconazoles=20：1)
It is made according to common process, wherein pyraziflumid 20g, prothioconazoles 1g, cornstarch (dispersing aid) 0.5g, polyethylene glycol (binding agent) 0.1g, polyvinyl alcohol (sustained release agent) 0.1g, kaolin (filler) complement to 100g.
The part by weight of pyraziflumid and prothioconazoles can be 20 in the present embodiment：1~1：Change between 20, two The mass percentage of person can change between 0.5%~85%, be also adjusted accordingly therewith using the proportioning of auxiliary agent, be formed New embodiment.
Prothioconazoles can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, Tebuconazole, nitrile bacterium azoles, tricyclazole, tetraconazole, penconazole or fluorine bacterium azoles form new embodiment.
Embodiment 8：10%pyraziflumid penconazole seed treatment suspending agents (pyraziflumid：Penconazole= 1：1)
It is made according to common process, wherein pyraziflumid 5g, penconazole 5g, naphthalenesulfonate formaldehyde condensation compound is (scattered Agent) 1.4g, lauryl sodium sulfate (wetting agent) 0.5g, fatty alcohol polyoxyethylene ether (bleeding agent) 0.5g, xanthans (thickening Agent) 0.2g, organosilicon (defoamer) 0.1g, ethylene glycol (antifreezing agent) 0.3g, acid scarlet (warning coloration) 0.5g, deionized water benefit Enough to 100g.
The part by weight of pyraziflumid and penconazole can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 0.5%~80%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Penconazole can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, penta Azoles alcohol, nitrile bacterium azoles, tricyclazole, tetraconazole, penconazole or prothioconazoles form new embodiment.
Embodiment 9：15%pyraziflumid Tebuconazole suspension seed-coating agents (pyraziflumid：Tebuconazole=1：5)
It is made according to common process, wherein pyraziflumid 2.5g, Tebuconazole 12.5g, lignosulfonates are (scattered Agent) 5g, dioctyl sulfosuccinate (bleeding agent) 2g, starch (film forming agent) 3g, carboxymethyl cellulose (film forming agent) 2g are organic Silicon (defoamer) 0.08g, propane diols (antifreezing agent) 2g, acid scarlet (warning coloration) 3g, deionized water complement to 100g.
The part by weight of pyraziflumid and Tebuconazole can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 0.5~80%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Tebuconazole can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, nitrile Bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 10：24%pyraziflumid hexaconazole suspending agents (pyraziflumid：SSF 126=1：2)
It is made according to common process, wherein pyraziflumid 8g, Fluoxastrobin 16g, sodium lignin sulfonate (dispersant) 4g, lauryl sodium sulfate (wetting agent) 2g, ethylene glycol (antifreeze) 4g, bentonite (thickener) 0.12g, organic silicone (disappear Infusion) 0.4g, deionized water mended to 100g.
Pyraziflumid and the part by weight of hexaconazole can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 5%~80%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Hexaconazole can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, triazolone, Tebuconazole, nitrile Bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 11：20%pyraziflumid nitrile bacterium azoles missible oil (pyraziflumid：Nitrile bacterium azoles=3：1)
It is made according to common process, wherein pyraziflumid 15g, nitrile bacterium azoles 5g, calcium dodecyl benzene sulfonate (emulsification Agent) 3g, octyl phenol polyoxyethylene ether (emulsifying agent) 4g, dimethyl sulfoxide (cosolvent) 10g, goes turpentine oil to mend to 100g.
Pyraziflumid and the part by weight of nitrile bacterium azoles can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 1%~60%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Nitrile bacterium azoles can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, triazolone, hexaconazole, penta Azoles alcohol, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 12：51%pyraziflumid tricyclazole wettable powders (pyraziflumid：Tricyclazole=50： 1)
It is made according to common process, wherein pyraziflumid 50g, tricyclazole 1g, lauryl sodium sulfate (wetting agent) 2g, sodium lignin sulfonate (dispersant) 3g, NNO (dispersant) 5g, kaolin complement to 100g.
The part by weight of pyraziflumid and tricyclazole can be 50 in the present embodiment：1~1：Change between 50, both Mass percentage can change between 1%~85%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Tricyclazole can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, hexaconazole, Tebuconazole, nitrile Bacterium azoles, triazolone, tetraconazole, penconazole, fluorine bacterium azoles or prothioconazoles form new embodiment.
Embodiment 13：30%pyraziflumid triflumizole wettable powders (pyraziflumid：Fluorine bacterium azoles=1：5)
It is made according to common process, wherein pyraziflumid 5g, fluorine bacterium azoles 25g, lauryl sodium sulfate (wetting agent) 2g, sodium lignin sulfonate (dispersant) 3g, NNO (dispersant) 5g, kaolin complement to 100g.
Pyraziflumid and the part by weight of fluorine bacterium azoles can be 20 in the present embodiment：1~1：Change between 20, both Mass percentage can change between 1%~85%, be also adjusted accordingly, formed new therewith using the proportioning of auxiliary agent Embodiment.
Fluorine bacterium azoles can also be substituted for difenoconazole, propiconazole, Flusilazole, epoxiconazole, hexaconazole, Tebuconazole, nitrile Bacterium azoles, triazolone, tetraconazole, penconazole, tricyclazole or prothioconazoles form new embodiment.
2nd, biological activity determination and field control effectiveness test example
Pesticide is made in the combination of active principles of different pesticides, is current exploitation and develops novel pesticide and prevention agriculturally A kind of effective and quick way of resistance pest and disease damage.After the pestsides synthesis of different cultivars, three kinds of type of action are typically exhibited： Summation action, synergistic effect and antagonism.But it is specially which kind of effect, it is unpredictable, only could really by a large number of experiments It is fixed.
Inventor has found pyraziflumid and a kind of triazole bactericidal agent, triazole type is killed by substantial amounts of screening test Microbial inoculum be selected from difenoconazole, propiconazole, Flusilazole, epoxiconazole, hexaconazole, Tebuconazole, nitrile bacterium azoles, triazolone, tetraconazole, Have after any one compounding in penconazole, fluorine bacterium azoles, tricyclazole and prothioconazoles to multiple diseases obvious synergistic Effect.Thus, present example provides application of the above-mentioned bactericidal composition in prevention powdery mildew of cucumber, banana freckle, effect The simple addition of not exclusively two kinds medicaments, is specifically illustrated with following bioassay example.
One) biological activity determination example
Pyraziflumid and difenoconazole, propiconazole, Flusilazole, epoxiconazole, hexaconazole, Tebuconazole, nitrile bacterium azoles, three Oxazolone, tetraconazole, penconazole, fluorine bacterium azoles, tricyclazole or prothioconazoles compounding try the joint toxicity measuring of banana freckle Test
For trying object：Macrophoma musae bacterium (Macrophoma musae (Cooke) Berl.et Vogl.).
Experiment uses mycelial growth rate method：Aqua sterilisa to contain suitable acetone and Tween-80 is used as control (CK). Take 4mL liquids to be added in the conical flask equipped with the hot culture mediums of 36mL (PDA culture medium, 45-50 DEG C), after shaking up, pour into rapidly Diameter 90mm glass culture dish, each culture dish pour into band medicine culture medium 10mL, each handle 4 repetitions, horizontal rest, cooling Afterwards tablet.Bacteria cake is cut for examination colony edge from culture 3d with diameter 5mm card punch, with choosing pin by one with mycelia Face is connected on the malicious culture medium of band, and all operations carry out sterile working in superclean bench.24 ± 1 DEG C of constant temperature is placed on after processing Camera bellows culture in sterile culture case, the colony diameter of each processing is measured after 5d respectively using crossing method, calculates colony diameter Average value, mycelial growth inhibition rate.
Mode of application judges to use co-toxicity coefficient (CTC) method.The calculation formula of co-toxicity coefficient is as follows：
Survey toxicity index (ATI)=(standard agent EC50/ reagent agent EC50)×100
In theoretical toxicity index (TTI)=A medicaments ATI × mixture in percentage composition+B medicaments ATI × mixture of A B hundred Divide content
Co-toxicity coefficient (CTC)=[mixture actual measurement toxicity index (ATI)/mixture theoretical toxicity index (TTI)] × 100
When CTC≤80, then composition shows as antagonism, and as 80 ＜ CTC ＜ 120, then composition shows as being added and makees With when CTC >=120, then composition shows as synergistic effect.
Result of the test：Pyraziflumid and difenoconazole, propiconazole, Flusilazole, epoxiconazole, hexaconazole, Tebuconazole, To Macrophoma musae bacterium after nitrile bacterium azoles, triazolone, tetraconazole, penconazole, fluorine bacterium azoles, tricyclazole or prothioconazoles compounding Joint toxicity measuring the results are shown in Table 1-13.
Joint toxicity measuring result of the test of 1 composition of table to Macrophoma musae bacterium
1 co-toxicity of table test the result shows that, pyraziflumid and difenoconazole compounding 50：1~1：50 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring in ratio range, there is synergistic effect.Especially It is 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 2 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.19 100.0 / /
Propiconazole B 1.08 17.6 / /
A：B=50：1 0.14 135.7 98.4 137.94
A：B=40：1 0.12 158.3 98.0 161.58
A：B=20：1 0.1 190.0 96.1 197.76
A：B=10：1 0.09 211.1 92.5 228.21
A：B=5：1 0.08 237.5 86.3 275.31
A：B=1：1 0.11 172.7 58.8 293.77
A：B=1：5 0.25 76.0 31.3 242.60
A：B=1：10 0.36 52.8 25.1 210.40
A：B=1：20 0.43 44.2 21.5 205.36
A：B=1：40 0.74 25.7 19.6 130.98
A：B=1：50 0.81 23.5 19.2 122.12
2 co-toxicity of table test the result shows that, pyraziflumid and propiconazole compound are 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 3 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.22 100.0 / /
Flusilazole B 0.98 22.4 / /
A：B=50：1 0.17 129.4 98.5 131.41
A：B=40：1 0.16 137.5 98.1 140.15
A：B=20：1 0.12 183.3 96.3 190.36
A：B=10：1 0.1 220.0 92.9 236.69
A：B=5：1 0.12 183.3 87.1 210.55
A：B=1：1 0.12 183.3 61.2 299.44
A：B=1：5 0.21 104.8 35.4 296.15
A：B=1：10 0.29 75.9 29.5 257.17
A：B=1：20 0.4 55.0 26.1 210.39
A：B=1：40 0.68 32.4 24.3 132.92
A：B=1：50 0.75 29.3 24.0 122.38
3 co-toxicity of table test the result shows that, pyraziflumid and Flusilazole compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 4 composition of table to Macrophoma musae bacterium
4 co-toxicity of table test the result shows that, pyraziflumid and epoxiconazole compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 200, and synergistic effect is notable.
Joint toxicity measuring result of the test of 5 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.24 100.0 / /
Hexaconazole B 2.46 9.8 / /
A：B=50：1 0.20 120.0 98.2 122.16
A：B=40：1 0.16 150.0 97.8 153.38
A：B=20：1 0.12 200.0 95.7 208.98
A：B=10：1 0.14 171.4 91.8 186.75
A：B=5：1 0.13 184.6 85.0 217.30
A：B=1：1 0.18 133.3 54.9 242.96
A：B=1：5 0.38 63.2 24.8 254.70
A：B=1：10 0.47 51.1 18.0 284.32
A：B=1：20 0.69 34.8 14.1 247.50
A：B=1：40 1.24 19.4 12.0 161.87
A：B=1：50 1.62 14.8 11.5 128.54
5 co-toxicity of table test the result shows that, pyraziflumid and hexaconazole compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 6 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.28 100.0 / /
Tebuconazole B 1.63 17.2 / /
A：B=50：1 0.21 133.3 98.4 135.53
A：B=40：1 0.18 155.6 98.0 158.76
A：B=20：1 0.11 254.5 96.1 265.00
A：B=10：1 0.12 233.3 92.5 252.33
A：B=5：1 0.18 155.6 86.2 180.47
A：B=1：1 0.16 175.0 58.6 298.69
A：B=1：5 0.35 80.0 31.0 258.22
A：B=1：10 0.47 59.6 24.7 241.12
A：B=1：20 0.64 43.8 21.1 207.13
A：B=1：40 1.2 23.3 19.2 121.54
A：B=1：50 1.16 24.1 18.8 128.38
6 co-toxicity of table test the result shows that, pyraziflumid and Tebuconazole compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 7 composition of table to Macrophoma musae bacterium
7 co-toxicity of table test the result shows that, pyraziflumid and myclobutanil compositional are 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 8 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.21 100.0 / /
Triazolone B 4.57 4.6 / /
A：B=50：1 0.16 131.3 98.1 133.75
A：B=40：1 0.15 140.0 97.7 143.34
A：B=20：1 0.11 190.9 95.5 200.00
A：B=10：1 0.12 175.0 91.3 191.62
A：B=5：1 0.12 175.0 84.1 208.09
A：B=1：1 0.16 131.3 52.3 250.97
A：B=1：5 0.35 60.0 20.5 292.74
A：B=1：10 0.68 30.9 13.3 232.75
A：B=1：20 0.85 24.7 9.1 270.36
A：B=1：40 2.47 8.5 6.9 122.82
A：B=1：50 2.68 7.8 6.5 121.19
8 co-toxicity of table test the result shows that, pyraziflumid and triazolone compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 9 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.23 100.0 / /
Tricyclazole B 4.18 5.5 / /
A：B=50：1 0.17 135.3 98.1 137.85
A：B=40：1 0.16 143.8 97.7 147.14
A：B=20：1 0.12 191.7 95.5 200.70
A：B=10：1 0.13 176.9 91.4 193.55
A：B=5：1 0.15 153.3 84.3 182.00
A：B=1：1 0.20 115.0 52.8 218.00
A：B=1：5 0.42 54.8 21.3 257.68
A：B=1：10 0.89 25.8 14.1 183.37
A：B=1：20 0.97 23.7 10.0 237.06
A：B=1：40 2.34 9.8 7.8 125.90
A：B=1：50 2.56 9.0 7.4 122.15
9 co-toxicity of table test the result shows that, pyraziflumid and tricyclazole compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 10 composition of table to Macrophoma musae bacterium
10 co-toxicity of table test the result shows that, pyraziflumid and tetraconazole compounding 50：1~1：50 match somebody with somebody 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring than in the range of, there is synergistic effect.Especially It is 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 11 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.24 100.0 / /
Prothioconazoles B 2.58 9.3 / /
A：B=50：1 0.16 150.0 98.2 152.72
A：B=40：1 0.18 133.3 97.8 136.35
A：B=20：1 0.12 200.0 95.7 209.03
A：B=10：1 0.14 171.4 91.8 186.83
A：B=5：1 0.13 184.6 84.9 217.49
A：B=1：1 0.20 120.0 54.7 219.57
A：B=1：5 0.54 44.4 24.4 182.01
A：B=1：10 0.71 33.8 17.5 192.64
A：B=1：20 0.85 28.2 13.6 207.29
A：B=1：40 1.71 14.0 11.5 121.89
A：B=1：50 1.68 14.3 11.1 128.92
11 co-toxicity of table test the result shows that, pyraziflumid and prothioconazoles compounding 50：1~1：50 match somebody with somebody 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring than in the range of, there is synergistic effect.Especially It is 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 12 composition of table to Macrophoma musae bacterium
Processing EC50(μg/mL) ATI TTI Co-toxicity coefficient CTC
pyraziflumid A 0.27 100.0 / /
Penconazole B 4.87 5.5 / /
A：B=50：1 0.20 135.0 98.1 137.55
A：B=40：1 0.19 142.1 97.7 145.46
A：B=20：1 0.14 192.9 95.5 201.94
A：B=10：1 0.16 168.8 91.4 184.60
A：B=5：1 0.13 207.7 84.3 246.50
A：B=1：1 0.24 112.5 52.8 213.18
A：B=1：5 0.67 40.3 21.3 189.31
A：B=1：10 0.85 31.8 14.1 224.79
A：B=1：20 0.97 27.8 10.0 277.19
A：B=1：40 2.17 12.4 7.8 158.54
A：B=1：50 3.04 8.9 7.4 120.08
12 co-toxicity of table test the result shows that, pyraziflumid and penconazole compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Joint toxicity measuring result of the test of 13 composition of table to Macrophoma musae bacterium
13 co-toxicity of table test the result shows that, pyraziflumid and fluorine bacterium azoles compounding 50：1~1：50 proportioning In the range of 120 are all higher than to the co-toxicity coefficient CTC of Macrophoma musae bacterium joint toxicity measuring, there is synergistic effect.Especially 20：1~1：In 20 ratio range, CTC is all higher than 180, and synergistic effect is notable.
Two) field control effectiveness test example
1st, to the field control effectiveness test of powdery mildew of cucumber
Test and carried out in April, 2016 in one green house of vegetables of Shouguang City of Shandong Province, which plants cucumber year after year, during experiment Lighter, investigation state of an illness radix before medicine occurs for powdery mildew of cucumber, takes at random per cell at 4 points, whole leaves of 2 plants of cucumber of every investigation Piece, the percentage that every leaf is accounted for leaf area by scab are classified record.
Stage division：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for whole leaf area below 5%；
3 grades：Lesion area accounts for whole below leaf area 6%-10%；
5 grades：Lesion area accounts for whole below leaf area 11%-20%；
7 grades：Lesion area accounts for whole below leaf area 21%-40%；
9 grades：Lesion area accounts for whole more than 40%.
Experiment shares medicine three times, each medication interval 7 days, 14 days investigation results after last time medication.
Calculation formula is as follows：
Prevention effect (%)=(1- (CK0×PT1)/(CK1×PT0))×100
In formula：CK0Disease index before expression blank district dispenser；
CK1Disease index after expression blank district dispenser；
PT0Disease index before expression chemicals treatment district dispenser；
PT1Disease index after expression chemicals treatment district dispenser.
Data can be drawn from table 14, and the various formulation synergistic effects of composition containing pyraziflumid are obvious；Last 14d after secondary dispenser, each compound drug are also significantly better than single dose to the prevention effect of powdery mildew of cucumber.
Field control effect of the medicaments such as 14 composition of table to powdery mildew of cucumber
2nd, to the field control effectiveness test of banana freckle
Test first for banana freckle morbidity when in June, 2016 is in Guangxi Gold fringe company one banana base progress, experiment Phase, state of an illness radix is investigated before medicine, takes 3 plants of investigation at random per cell, and blade investigates every plant and investigates 8 by the order from top down Leaf.Record the total number of sheets of investigation, the sick number of sheets at different levels.The percentage that every leaf is accounted for leaf area by scab is classified record.
Stage division：
0 grade：Disease-free spot；
1 grade：Lesion area accounts for whole leaf area below 5%；
3 grades：Lesion area accounts for whole below leaf area 6%-10%；
5 grades：Lesion area accounts for whole below leaf area 11%-25%；
7 grades：Lesion area accounts for whole below leaf area 26%-50%；
9 grades：Lesion area accounts for whole more than 50%.
Experiment shares medicine three times, each medication interval 7 days, 10 days investigation results after last time medication.
Calculation formula is as follows：
Prevention effect (%)=(1- (CK0×PT1)/(CK1×PT0))×100
In formula：CK0Disease index before expression blank district dispenser；
CK1Disease index after expression blank district dispenser；
PT0Disease index before expression chemicals treatment district dispenser；
PT1Disease index after expression chemicals treatment district dispenser.
Data can be drawn from table 15, and the various formulation synergistic effects of composition containing pyraziflumid are obvious；Last 10d after secondary dispenser, each compound drug are also significantly better than single dose to the prevention effect of banana freckle.
Field control effect of 15 composition containing pyraziflumid of table to banana freckle
Combined from containing pyraziflumid in terms of to powdery mildew of cucumber, the field control effectiveness test result of banana freckle, it is each multiple Dose out powders have powdery mildew and scab good prevention effect, and preventive effect is significantly better than single dose.Illustrate that there is compounding synergy to make With the lasting period extends, and can reduce dosage and spraying times, delay the resistance to the action of a drug to produce, while can reduce cost accounting.
The foregoing is merely a prefered embodiment of the invention, is not intended to limit the invention, it is all the present invention spirit and All any modification, equivalent and improvement made within principle etc., should all be included in the protection scope of the present invention.

Claims (6)

1. a kind of bactericidal composition containing pyraziflumid, contain active components A and active ingredient B, its feature in composition It is：The mass ratio of active components A and active ingredient B are 50：1~1：50, the active components A is pyraziflumid, Active ingredient B is a kind of triazole bactericidal agent, triazole bactericidal agent be selected from difenoconazole, propiconazole, Flusilazole, epoxiconazole, It is any one in triazolone, hexaconazole, Tebuconazole, nitrile bacterium azoles, tricyclazole, tetraconazole, penconazole, fluorine bacterium azoles and prothioconazoles Kind.
2. the bactericidal composition according to claim 1 containing pyraziflumid, it is characterised in that：Active components A and work Property component B mass ratio be 20：1~1：20.
3. the bactericidal composition according to claim 1 or 2 containing pyraziflumid, it is characterised in that：Composition can be with The formulation made has suspension seed-coating agent, granule, microcapsule suspending agent, microemulsion, aqueous emulsion, suspending agent, wettable powder, moisture Shot agent or missible oil.
4. the bactericidal composition according to claim 3 containing pyraziflumid, it is characterised in that：In composition effectively into The gross mass percentage composition divided is 0.5%~85%.
5. the bactericidal composition according to any one of claims 1 to 4 containing pyraziflumid is used to prevent crop disease Purposes.
6. purposes according to claim 5, it is characterised in that：The disease is target spot, canker, blight dis-ease, rust Disease, ring spot, sclerotiniose, smut, full rot, root rot, gray mold, damping-off, banded sclerotial blight, bakanae disease, droop, sclerotium Disease, poliosis, downy mildew, samping off, brown spot, powdery mildew, anthracnose, early blight, leaf mold, leaf spot, scab, black mole Disease, shot hole, epidemic disease, bacterial wilt, base rot disease, verticillium wilt, clubroot.
CN201610885583.XA 2016-10-10 2016-10-10 A kind of bactericidal composition and its application containing pyraziflumid Withdrawn CN107912437A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610885583.XA CN107912437A (en) 2016-10-10 2016-10-10 A kind of bactericidal composition and its application containing pyraziflumid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610885583.XA CN107912437A (en) 2016-10-10 2016-10-10 A kind of bactericidal composition and its application containing pyraziflumid

Publications (1)

Publication Number Publication Date
CN107912437A true CN107912437A (en) 2018-04-17

Family

ID=61892535

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610885583.XA Withdrawn CN107912437A (en) 2016-10-10 2016-10-10 A kind of bactericidal composition and its application containing pyraziflumid

Country Status (1)

Country Link
CN (1) CN107912437A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108200911A (en) * 2017-07-25 2018-06-26 吉林农业科技学院 A kind of composition comprising biphenyl pyrazine bacterium amine and application thereof
CN109197875A (en) * 2017-06-30 2019-01-15 燕化永乐（乐亭）生物科技有限公司 A kind of bactericidal composition
WO2019186356A1 (en) * 2018-03-26 2019-10-03 Upl Ltd Fungicidal combinations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009023994A (en) * 2007-06-21 2009-02-05 Nippon Nohyaku Co Ltd Agricultural and horticultural bactericide composition and usage thereof
JP2014224067A (en) * 2013-05-16 2014-12-04 日本農薬株式会社 Bactericide composition for agricultural and horticultural use and use method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009023994A (en) * 2007-06-21 2009-02-05 Nippon Nohyaku Co Ltd Agricultural and horticultural bactericide composition and usage thereof
JP2014224067A (en) * 2013-05-16 2014-12-04 日本農薬株式会社 Bactericide composition for agricultural and horticultural use and use method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
杨吉春等: "近五年公开的新杀菌剂及其合成研究进展", 《精细化工中间体》 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109197875A (en) * 2017-06-30 2019-01-15 燕化永乐（乐亭）生物科技有限公司 A kind of bactericidal composition
CN108200911A (en) * 2017-07-25 2018-06-26 吉林农业科技学院 A kind of composition comprising biphenyl pyrazine bacterium amine and application thereof
CN108200911B (en) * 2017-07-25 2020-04-07 吉林农业科技学院 Composition containing biphenyl pyrazinyl bacteria amine and application thereof
WO2019186356A1 (en) * 2018-03-26 2019-10-03 Upl Ltd Fungicidal combinations

Similar Documents

Publication Publication Date Title
CN100502653C (en) Compound bactericidal agent for prevention and control of wheat fungi diseases, and its application
CN105409961B (en) A kind of bactericidal composition of containing fluazinam and its application
TWI617244B (en) Fungicidal composition and the use thereof
CN101983565A (en) Sterilization composite containing fluopyram
CN102630679A (en) Pesticide composition containing orysastrobin
CN107912437A (en) A kind of bactericidal composition and its application containing pyraziflumid
CN102484998A (en) Broad-spectrum combined bactericide
CN106489956A (en) Composition pesticide and its application
CN106689140A (en) Pyraziflumid-containing bactericidal composition and application thereof
CN107494550A (en) A kind of bactericidal composition containing fluorine azoles bacterium acyl azanol and 2-cyano-3-amino-3-phenylancryic acetate
CN106857599A (en) A kind of bactericidal composition containing pyraclostrobin and folpet and its application
CN108184861A (en) A kind of bactericidal composition and its application containing pyraziflumid
CN102657180B (en) Sterilization composition containing tetraconazole and trifloxystrobin
CN101697722B (en) Famoxadone-containing bactericidal composition
CN104770374B (en) A kind of bactericidal composition
CN106172453B (en) A kind of bactericidal composition and its application
CN108200909A (en) A kind of bactericidal composition
CN107912443A (en) A kind of bactericidal composition and its application
CN108419798A (en) A kind of bactericidal composition and its application containing alkene oxime amine
CN106719688A (en) A kind of bactericidal composition and its application containing pyraziflumid
CN106376598B (en) Pesticidal combination containing Empedobacter brevis and Cupric sulfate
CN107771837A (en) A kind of bactericidal composition and its application containing pyraziflumid
CN107711864A (en) Agricultural bactericidal composition and purposes for industrial crops
CN106719744A (en) Bactericidal composition and its application
CN105724384A (en) Sterilization composition containing fluopicolide and application thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20180417