CN108200911B - Composition containing biphenyl pyrazinyl bacteria amine and application thereof - Google Patents
Composition containing biphenyl pyrazinyl bacteria amine and application thereof Download PDFInfo
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- CN108200911B CN108200911B CN201710609856.2A CN201710609856A CN108200911B CN 108200911 B CN108200911 B CN 108200911B CN 201710609856 A CN201710609856 A CN 201710609856A CN 108200911 B CN108200911 B CN 108200911B
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
- A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/12—Powders or granules
- A01N25/14—Powders or granules wettable
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
The invention relates to a composition containing biphenyl pyrazinyl bacteria amine and application thereof, and particularly provides a bactericidal composition which is characterized by comprising a bactericidal active ingredient A and a bactericidal active ingredient B, wherein the bactericidal active ingredient A is a compound shown as the following formula (I), the bactericidal active ingredient B is selected from one of prothioconazole, boscalid and fluazinam, and the compound shown as the formula (I) is named as the biphenyl pyrazinyl bacteria amine. The bactericidal composition can be used for synergistically preventing and treating ginseng sclerotinia rot, Chinese cabbage sclerotinia rot, strawberry gray mold, strawberry powdery mildew, cucumber gray mold, cucumber sclerotinia rot, tomato gray mold, tomato sclerotinia rot, eggplant gray mold, pepper gray mold and pepper sclerotinia rot, and has an unexpected synergistic effect.
Description
Technical Field
The invention belongs to the technical field of pesticides, and particularly relates to a composition containing biphenyl pyrazinyl bacteria amine and application thereof.
Background
Pyraziflumumid (test code NNF-0721) (hereinafter referred to as biphenylpyrazinecarboxamide) is known under the chemical name of N- (3',4' -difluorobiphenyl-2-yl) -3- (trifluoromethyl) pyrazine-2-carboxamide, is produced by japan pesticide co.
Chinese patent application No. 200680046968.1 discloses the structural formula of biphenyl pyrazinamide, and describes the preparation method and the experimental effect of preventing and treating plant diseases.
WO2016060230a1 discloses formulations of biphenylpyrazinecarboxamide, wherein it is mentioned that as a second active ingredient in the formulation any fungicide can be used, but it is not clear which biphenylpyrazinecarboxamide and which fungicide combinations can have a synergistic effect, which have an antagonistic effect, and which can produce an additive effect.
The prothioconazole not only has good systemic activity, excellent protection, treatment and eradication activity, but also has long lasting period. A large number of field efficacy tests show that the prothioconazole has good safety and good disease prevention and treatment effects on crops, and is mainly used for preventing and treating cereal crops such as wheat, barley, rape,
Peanut, rice and bean crops.
The boscalid is mainly used for preventing and treating powdery mildew, gray mold, various rot diseases, brown rot, root rot and the like, and is mainly used for preventing and treating diseases of rape, grapes, fruit trees, vegetables, field crops and the like.
The fluazinam is a protective bactericide, can prevent and treat diseases caused by botrytis cinerea, is very effective on alternaria, botrytis, phytophthora, monascus, sclerotinia and black reclamation bacteria, has a good effect on botrytis cinerea of benzimidazoles and dicarboximide bactericides, is rain wash resistant, has a long lasting period, has an excellent effect of controlling phytophagous mites, also has an excellent effect of preventing clubroot of cruciferous plants, and also has a good effect of preventing rice damping-off caused by rhizopus.
However, in the process of controlling crop diseases, the single agent has large dosage or improved resistance after long-term use, and the control effect is reduced.
Disclosure of Invention
In order to solve the technical problems, the invention provides a bactericidal composition, which is characterized by comprising a bactericidal active ingredient A and a bactericidal active ingredient B, wherein the bactericidal active ingredient A is a compound shown as the following formula (I):
the bactericidal active ingredient B is selected from one of prothioconazole, boscalid and fluazinam.
Wherein, the compound of formula (I) is named as biphenyl pyrazinyl bacteria amine in the invention.
Preferably, in the bactericidal composition, the weight ratio of the bactericidal active ingredient A to the bactericidal active ingredient B is 1:100 to 100:1, and preferably, the weight ratio of the bactericidal active ingredient A to the bactericidal active ingredient B is 1:80 to 80: 1. Particularly preferably, the weight ratio of the biphenylpyrazinamide to the prothioconazole is 1:3, 3:1 or 1:1, the weight ratio of the biphenylpyrazinamide to the boscalid is 1:40, 10:1 or 1:8, and the weight ratio of the biphenylpyrazinamide to the fluazinam is 10:1, 8:1 or 1: 20.
Preferably, in the above bactericidal composition, the sum of the weight of the bactericidal active ingredient a and the weight of the bactericidal active ingredient B accounts for 1 to 70 percent of the weight of the bactericidal composition, and preferably accounts for 5 to 60 percent of the weight of the bactericidal composition.
Preferably, the bactericidal composition further comprises a third bactericidal component, and the third bactericidal component is one selected from the group consisting of amide bactericides, dicarboximide bactericides, triazole bactericides, imidazole bactericides, oxazole bactericides, morpholine bactericides, pyrrole bactericides, pyridine bactericides, pyrimidine bactericides, quinazolinone bactericides, carbamate bactericides, organophosphorus bactericides, thiocarbamate bactericides, copper preparations, bactericides and other bactericides.
Preferably, the amide fungicide is selected from thifluzamide, propionibamide, fenhexamid, fenpropamide, silthiopham, furametpyr, zoxamide, metalaxyl-M, metalaxyl, benalaxyl, diclocyanamide, sulfentram, sulfsulfamide, tiadinil, isotianil, flutolanil, cyflufenamid, penthiopyrad, mandipropamid, carboxin, alkene oxime amine, flurobisphenol, orysastrobin, fluoxastrobin, fluopyram, cyazofamid, valpromethacarb, fluoxastrobin, coumoxystrobin, pyraoxystrobin, pyraclostrobin, clorstrobin, kresoxim-methyl, trifloxystrobin, kresoximesoxim-methyl, dimoxystrobin, metominostrobilurin-methyl, metominostrobin, metominostrobilurin-ethyl, metominostrobin, metominostrobil;
the dicarboximide bactericide is selected from procymidone, iprodione, vinclozolin, fluocinolone, myclozolin, ethirimol, sclerotium, captafol, captan, folpet, climbazole, sterile phosphorus, and sulfur chlorophenylimine;
the triazole bactericide is selected from epoxiconazole, triadimefon, diniconazole, myclobutanil, tebuconazole, propiconazole, prothioconazole, metconazole, tetraconazole, triticonazole, ipconazole, fenbuconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, penconazole, simeconazole, triadimenol, bitertanol and tricyclazole;
the imidazole bactericide is selected from carbendazim, prochloraz, thiophanate-methyl, probenazole, prothioconazole, fuberidazole, imazalil, benomyl and triflumizole;
the oxazole bactericide is selected from hymexazol;
the morpholine bactericide is selected from dimethomorph, flumorph and tridemorph;
the pyrrole bactericide is selected from dimethachlon, fenpiclonil and fludioxonil;
the pyridine bactericide is selected from the group consisting of pyribenzoxim, cyprodinil, bixafen, fluopicolide, pyrimethanil, buthionine and boscalid;
the pyrimidine bactericide is selected from cyprodinil, fluopyram, mepanipyrim, pyrimethanil, fenarimol, fluoropyrimidinol, bupirimate, dimetrimol, ethirimol, pyrizone and cyprodinol;
the quinazolinone bactericide is selected from dithianon;
the carbamate bactericide is selected from diethofencarb, iprovalicarb, benthiavalicarb, propamocarb, sulbencarb and amikazadol;
the organic phosphorus bactericide is selected from diphacinone, iprobenfos, pyrazophos, tolclofos-methyl, pyrifenozin, ethylphosphonic acid, phosphorus for seed soaking, and captafos;
the thiocarbamate fungicide is selected from mancozeb, maneb, zineb, propineb, amobam, thiram, ziram, thiram oxide, morbus, ferbam, sodium metiram, thiram, sulphur, metiram and zineb;
the copper preparation is selected from Bordeaux mixture, copper acetate, copper carbonate, copper oxychloride, copper silicate, basic copper sulfate, cuprous oxide, and oxine-copper;
the bactericide is selected from blasticidin, kasugamycin, polyoxin, validamycin, dicentriamycin, bismerthiazol, bronopol, copper hydroxide, ethylicin, sodium diuron, quinconazole, terramycin, bismerthiazol, probenazole, thielavone, thiediazole copper, xinjunan and thiazole zinc;
other bactericide is selected from isoprothiolane copper oxychloride, metrafenone, spiroxamine, fluazinam, indoxyl flusulfamide, trichlamic, thiophanate, dichloronaphthoquinone, fenpyrazamine, cyhalothrin, thiophanate, fluazinam,
the third sterilization component accounts for 1-50% of the sterilization composition by weight, preferably, 1-30%.
Preferably, in the above bactericidal composition, the bactericidal composition further comprises a pesticide carrier and a pesticide adjuvant, and the sum of the weight of the pesticide carrier and the weight of the pesticide adjuvant accounts for 1 to 90 percent of the weight of the bactericidal composition, preferably 1 to 80 percent of the weight of the bactericidal composition.
In the above bactericidal composition, the pesticide carrier is a liquid carrier (or a solvent) or a solid carrier, wherein the liquid carrier is selected from one or more of water, aromatic hydrocarbons, aliphatic hydrocarbons, ketones, ethers, and the like, preferably, from one or more of water, acetone, cyclohexanone, xylene, benzene, cyclohexane, isopropanol, ethylene glycol, sorbitol, methanol, ethanol, butanol, dimethylformamide, decalin, machine oil, petroleum ether, cyclohexanone, methyl oleate, methylated soybean oil, and the like, and a part of the liquid carrier may be used as a cosolvent, for example, methanol, phenol, isoamyl alcohol, dimethyl sulfoxide, ethyl acetate, butanone, dimethylformamide, tetradecanol, ethylene glycol, and the like may be used as a cosolvent.
The solid carrier is selected from one or more of natural or synthetic clays and silicates, naturally occurring rock flour, chalk, quartz, clays, montmorillonite, silica, diatomaceous earth, pumice, gypsum, talc, bentonite, kaolin, china clay, synthetic ground minerals, crushed and graded calcite, marble, pumice, sepiolite, dolomite and the like.
The pesticide adjuvant is selected from one or more of emulsifier, dispersant, wetting agent, thickener, defoamer, oxidant, antifreeze, disintegrant and the like.
Preferably, the emulsifier is selected from one or more of ethoxylated castor oil, polyoxyethylene phenethyl phenol ether oleate, alkylaryl polyoxyethylene polyoxypropylene ether, agricultural milk 0201B, agricultural milk 36#, alkylaryl formaldehyde resin polyoxyethylene ether, diphenyl phenol polyoxyethylene ether formaldehyde condensate, agricultural milk 1601#, sodium dodecyl sulfate, agricultural milk 700#, agricultural milk NP-7, agricultural milk 0203B, agricultural milk 2201#, agricultural milk S-80, agricultural milk 507#, agricultural milk NP-15, agricultural milk T-20, agricultural milk 100#, agricultural milk 600#, and the like.
Preferably, the dispersant is selected from one or more of sodium lignosulfonate, calcium lignosulfonate, sodium naphthalene sulfonate formaldehyde condensate, methyl naphthalene sulfonate formaldehyde condensate, sodium methylene naphthalene sulfonate, sodium methyl aminoethyl oleate, epoxy polyether, p-tert-butyl ether, piperonyl butyl ether, alkylamido taurate, dibutyl naphthalene sulfonate formaldehyde condensate, alkylphenol polyoxyethylene phosphate, methyl cellulose, sodium naphthol sulfonate formaldehyde condensate and the like.
Preferably, the wetting agent is selected from one or more of sodium sulfate, sodium lauryl sulfate, sodium methylene naphthalene sulfonate, sodium dodecylbenzene sulfonate, calcium dodecylbenzene sulfonate, sodium alkyl naphthalene sulfonate fatty alcohol polyoxyethylene ether, alkylphenol polyoxyethylene ether, and the like.
Preferably, the thickener is selected from one or more of carboxymethyl alcohol, polyvinyl acetate, xanthan gum, gelatin, gum arabic, polyvinylpyrrolidone, magnesium aluminum silicate, polyvinyl alcohol, polyethylene glycol, phenolic resin, shellac, soluble starch, carboxymethyl cellulose and sodium alginate.
Preferably, the defoaming agent is selected from one or more of natural products such as natural products, natural products and the like, wherein the natural products are natural products, and the natural products are natural products.
Preferably, the oxidant is selected from one or more of potassium chlorate, sodium chlorate, potassium perchlorate, sodium nitrate, potassium nitrate and potassium permanganate.
Preferably, the antifreeze is selected from one or more of ethylene glycol, propylene glycol, glycerol, urea and sodium chloride.
Preferably, the disintegrating agent is selected from one or more of ammonium sulfate, urea, sucrose, glucose, citric acid, succinic acid and sodium bicarbonate.
The invention also provides a composition preparation prepared from the composition, and the preparation is missible oil, a suspending agent, a water dispersible granule, an aqueous emulsion, a microemulsion, a soluble liquid agent, a wettable powder, a suspension seed coating agent, a granule or an oil suspending agent.
The above composition preparation can be prepared by conventional processing method, i.e. mixing active ingredient with liquid carrier or solid carrier, and adding one or more of the above adjuvants such as emulsifier, dispersant, etc. Typically, the germicidal composition includes at least one carrier and at least one surfactant. In each case, a homogeneous distribution of the active ingredient in the above-mentioned compositions should be ensured.
The invention also provides application of the bactericidal composition, and the bactericidal composition is used for preventing and treating plant diseases.
The invention also provides a method for preventing and treating plant diseases by applying the bactericidal composition to stem leaves, roots or plant seeds of plants in a bactericidal effective amount in a spraying mode, a root application mode or a seed coating mode.
Preferably, the plant diseases are wheat stripe rust, wheat leaf rust, wheat stem rust, wheat scab, wheat yellow dwarf, wheat soil-borne mosaic disease, wheat stripe mosaic disease, wheat streak mosaic disease, large, wheat loose smut, wheat stem smut, wheat stinking smut, wheat powdery mildew, wheat take-all, wheat sharp eyespot, wheat downy mildew, barley stripe disease, barley net blotch, wheat snow mold leaf blight, wheat helminthosporium root leaf spot, rice blast, false smut, rice sheath blight, rice bacterial leaf blight, bacterial stripe spot, rice flax leaf spot, bakanae disease, rice rot, rice core rot, rice stem rot, dwarf rice common dwarf rice dwarf, rice red blight, large, small leaf spot, corn round spot, corn head smut, corn black powdery mildew, corn bacterial wilt, corn dwarf mosaic disease, corn rough dwarf disease, maize dwarf disease, wheat leaf blight, wheat scab, wheat stripe disease, wheat streak disease, wheat scab, wheat stripe disease, wheat scab, wheat, Bacterial blight of corn, downy mildew of corn, curvularia leaf spot of corn, gray leaf spot of corn, anthracnose of corn, take-all disease of corn, head smut of sorghum, loose head smut of sorghum, long-grain head smut of sorghum, anthracnose of sorghum, glume blight of penicillium glumae, black bunch of sorghum, head rot of sorghum, head smut of sorghum, powdery mildew of millet, black ear of millet, red leaf disease of millet, black spot of sweet potato, root rot of garlic sprout, ring rot of potato, late blight of potato, early blight of potato, cancer and swelling of potato, leaf blight of soybean, top blight of soybean, sclerotinia rot of soybean, cyst nematode of soybean, gray leaf spot of soybean, downy mildew of soybean, bacterial blight of soybean, bacterial leaf spot of soybean, purple leaf spot of soybean, brown rot of soybean, root knot nematode of peanut, stem rot of peanut, peanut black spot, peanut kernel rot, soybean, gray spot of soybean, soybean spot of soybean, Peanut brown spot, peanut net blotch, peanut rust, peanut virus disease, cotton wilt, cotton verticillium wilt, cotton seedling disease, cotton angular leaf spot, cotton boll disease, flax rust, flax wilt, tobacco black shank, tobacco anthracnose, tobacco brown spot, beet powdery mildew, beet root rot, beet clump root disease, pear scab, pear rust, pear ring rot, pear black spot, pear brown rot, pear tree rot, apple rust, apple defoliation, apple rust, apple mosaic disease, apple virus disease, apple orchard root rot, apple violet rot, apple anthracnose, apple ring rot, apple penicilliosis, apple heart rot, apple tiger's skin disease, apple pox, apple rot, apple scab, apple heart disease, grape white rot, apple scab, grape white rot, apple scab, apple, Grape anthracnose, grape downy mildew, grape brown spot, grape spike brown blight, grape gray mold, jujube witches broom, jujube rust, jujube fruit rot, fruit tree root caner, solanaceous vegetable seedling stage disease, tomato virus disease, tomato leaf mold, tomato canker, tomato wilt, tomato yellow wilt, tomato early blight, tomato spot blight, tomato leaf mold, tomato gray mold, tomato powdery mildew, tomato brown rot, eggplant soft blight, pepper anthracnose, pepper blight, pepper scab, cucumber downy mildew, melon anthracnose, melon blight, melon powdery mildew, melon gray mold, cucumber scab, cucumber blight, cucumber sclerotium disease, cucumber bacterial angular leaf spot, cruciferous soft rot, cruciferous downy mildew, cruciferous black spot, cruciferous clubroomycete, cruciferous sclerotinia rot, ginseng sclerotinia, cruciferous black rot, cucumber rust, and the like, Peanut leaf spot, strawberry powdery mildew, banana leaf spot, banana wilt, banana bunchy top disease, banana tea leaf heart rot, banana anthracnose, banana scab, rape sclerotinia, rape downy mildew, sesame wilt, sesame stem blight, sunflower sclerotinia, sunflower black spot, peach plum brown rot, peach anthracnose, peach piercing disease, peach leaf shrinkage, peach rot, peach scab, peach gummosis, persimmon angular leaf spot, persimmon round spot, persimmon anthracnose, strawberry gray mold, Chinese chestnut dry rot, walnut black spot, walnut anthracnose, hawthorn blossom rot, kiwi fruit canker, bean bacterial blight, bean rust, bean blight, bean wilt, celery spot, celery early blight, onion purple spot or ginger blast and the like.
Preferably, the plant disease is ginseng sclerotinia rot, Chinese cabbage sclerotinia rot, strawberry gray mold, strawberry powdery mildew, cucumber gray mold, cucumber sclerotinia rot, tomato gray mold, tomato sclerotinia rot, eggplant gray mold, pepper gray mold or pepper sclerotinia rot.
Has the advantages that:
1) the synergistic effect is remarkable: in the above-mentioned fungicidal composition of the present invention, the bipyramid can form a synergistic effect with prothioconazole, boscalid and fluazinam, that is, the synergistic effect of the two components in the composition can make the total effect greater than or more durable than the sum of the effects obtained by the two (or more) components alone. In a method of providing control of plant disease wherein synergy is exhibited by a combination of active ingredients applied to a plant or seed, the active ingredients are applied in a synergistic weight ratio. The bactericidal composition can synergistically and synergistically prevent and treat ginseng sclerotinia rot, strawberry gray mold, cucumber powdery mildew or cucumber sclerotinia rot, and obtains an unexpected synergistic effect.
2) The use cost is reduced: the biphenylpyrazinamide and the prothioconazole, the boscalid or the fluazinam have obvious synergistic effect and obviously improved disease prevention effect, so that the application times are reduced, the use cost is reduced, the time and the labor are saved, and the economic benefit and the social benefit are obvious;
3) the development of resistance is delayed: the effective components of the compound bifeprazimide, prothioconazole, boscalid or fluazinam have different action mechanisms and bactericidal spectrums, the bactericidal effect is good, the use dosage of a single medicament is obviously reduced, the generation of pathogenic bacteria resistance is favorably delayed, the use range of the compound bifeprazimide is expanded, and the service life of the compound fluazimide is prolonged;
4) and (3) reduction of environmental pollution: the biphenyl pyrazinamide and prothioconazole, boscalid or fluazinam have excellent synergistic effect and disease prevention effect, so that the effects of preventing and controlling germs, resisting bacteria or inhibiting bacteria are improved, the prevention spectrum is expanded, the medicine using times can be reduced, the application dosage is obviously reduced, the environmental pollution is reduced, and the safety to people and livestock is improved.
Detailed Description
Example 1: experiment of combined toxicity effect of different compounding agents on ginseng sclerotinia rot
The test takes the sensitive strain of the ginseng sclerotinia sclerotiorum as an object to carry out formula screening of the compound medicament. After the related biphenyl pyrazinamide, prothioconazole, boscalid and fluazinam are dissolved by acetone, experiments are designed according to the mass ratio.
The inhibition rate of the bactericidal composition of the bactericides Bispyrazine, prothioconazole, boscalid and fluazinam single dose and active ingredients with different weights is determined by referring to a Sunweipei (1960) co-toxicity coefficient method.
The indoor combined toxicity test adopts a toxic medium method, namely adding a quantitative test agent (calculated according to effective components) into a PDA culture medium, taking the PDA culture medium without the agent as a control, cooling, inoculating sclerotinia sclerotiorum to be tested, after inoculating for 48 hours, respectively measuring the growth diameters of the control and the colonies treated differently by a cross method, and calculating the inhibition rate and the Effective Concentration (EC)50) The value is obtained.
Then, according to the concentration logarithm-hyphal growth inhibition rate probability value analysis (Bliss) method, the DPS2000 data processing software is used to calculate the toxicity regression equation and inhibitionMiddle concentration (EC)50) The value of (c). Then, the co-toxicity coefficient (CTC) of each mixture was determined according to the method described in Sun Yunpei (Sun).
The Actual Toxicity Index (ATI) of mixed preparation is standard preparation EC 50/mixed preparation EC50×100
Theoretical virulence index (TTI) of mixed preparation ═ sigma (virulence index of single preparation x the content of single preparation in mixed preparation)
The co-toxicity coefficient (CTC) of mixed preparation is mixed preparation actual toxicity index/mixed preparation theoretical toxicity index x 100
When the cotoxicity coefficient CTC is more than 120, the synergistic effect is achieved; 80 < CTC < 120, for addition; and if CTC is less than 80, antagonism is obtained.
Results of the indoor-link and virulence assays of the single agents of the biphenylpyrazinamide, the prothioconazole, the boscalid and the fluazinam and the compositions thereof against the ginseng sclerotinia strain are shown in the following tables 1, 2 and 3.
Table 1: indoor joint toxicity determination method of biphenyl pyrazinamide and fluazinam composition on ginseng sclerotinia sclerotiorum
Table 2: biphenyl pyrazinamide: indoor combined toxicity determination method of prothioconazole to ginseng sclerotinia sclerotiorum
| Name of medicament | Regression equation of virulence | EC50(mg/kg) | Correlation coefficient | Co-toxicity coefficient | Evaluation of |
| Prothioconazole | Y＝3.8148+0.7121X | 46.1714 | 0.9777 | --- | ---- |
| Biphenyl pyrazinamide | Y＝4.2346+0.5938X | 19.4530 | 0.8682 | ---- | ---- |
| Biphenyl pyrazinamide and prothioconazole 1:80 | Y＝4.1265+0.9233X | 8.8321 | 0.9817 | 514.05 | Efficiency enhancement |
| Biphenyl pyrazinamide and prothioconazole 1:40 | Y＝4.1265+0.9233X | 8.8321 | 0.9817 | 505.82 | Efficiency enhancement |
| Biphenyl pyrazinamide + propanamideThiconazole 1:10 | Y＝4.4196+0.5046X | 14.1300 | 0.9367 | 290.49 | Efficiency enhancement |
| Biphenyl pyrazinamide + prothioconazole 1:3 | Y＝4.7376+0.3434X | 5.8093 | 0.9252 | 591.63 | Efficiency enhancement |
| Biphenyl pyrazinamide + prothioconazole 3:1 | Y＝4.7694+0.2925X | 6.1429 | 0.8729 | 370.24 | Efficiency enhancement |
| Biphenyl pyrazinamide + prothioconazole 9:1 | Y＝4.4156+0.479X | 16.600 | 0.9921 | 124.38 | Efficiency enhancement |
| Biphenyl pyrazinamide + prothioconazole 20:1 | Y＝3.5537+1.2064X | 15.8047 | 0.8625 | 126.44 | Efficiency enhancement |
| Biphenyl pyrazinamide + prothioconazole 40:1 | Y＝4.7960+0.3641X | 3.6332 | 0.9899 | 543.09 | Efficiency enhancement |
| Biphenyl pyrazinamide + prothioconazole 80:1 | Y＝4.8434+0.1995X | 6.0948 | 0.9098 | 321.47 | Efficiency enhancement |
Table 3: biphenyl pyrazinamide: boscalid indoor combined toxicity determination method for ginseng sclerotinia sclerotiorum
| Name of medicament | Regression equation of virulence | EC50(mg/kg) | Correlation coefficient | Co-toxicity coefficient | Evaluation of |
| Biphenyl pyrazinamide | Y＝4.2346+0.5938X | 19.4530 | 0.8682 | ---- | --- |
| Boscalid | Y＝4.3440+0.4073X | 40.7950 | 0.9715 | ---- | ---- |
| Biphenyl pyrazinamide and boscalid 80:1 | Y＝4.8342+0.3875X | 2.6784 | 0.9280 | 731.01 | Efficiency enhancement |
| Biphenyl pyrazinamide and boscalid 20:1 | Y＝4.8342+0.3875X | 2.6784 | 0.9280 | 744.85 | Efficiency enhancement |
| 1:1 of biphenyl pyrazinamide and boscalid | Y＝4.2619+0.6718X | 12.5513 | 0.9807 | 209.89 | Efficiency enhancement |
| 1:20 of biphenyl pyrazinamide and boscalid | Y＝4.2746+0.7488X | 9.3125 | 0.8386 | 416.32 | Efficiency enhancement |
| 1:40 of biphenyl pyrazinamide and boscalid | Y＝4.8903+0.2690X | 2.5574 | 0.9719 | 1553.60 | Efficiency enhancement |
| 1:80 of biphenyl pyrazinamide and boscalid | Y＝3.8465+1.0028X | 14.1334 | 0.9003 | 284.79 | Efficiency enhancement |
Example 2: field efficacy test of different compound agents for preventing and treating gray mold, powdery mildew, sclerotinia sclerotiorum and the like
Respectively adopting single agents of biphenyl pyrazinamide, prothioconazole, boscalid and fluazinam and a composition preparation thereof to carry out spray treatment at the initial stage of the gray mold of the strawberry in a protected area, carrying out application twice at intervals of 7 days, and investigating the control effect 15 days after the second application; spraying twice at 7 days intervals at the early stage of powdery mildew of cucumber, and investigating 15 days after application; spraying twice at 7 days intervals at the initial stage of cucumber sclerotiniose occurrence in protected area, and investigating 20 days after application, and spraying twice at 7 days intervals at 20 days intervals at the initial stage of cucumber gray mold occurrence; spraying at the early stage of strawberry powdery mildew, applying the pesticide twice at intervals of 7 days, and investigating 15 days after the pesticide application; spraying twice at 7 days intervals at the early stage of Chinese cabbage sclerotinia sclerotiorum, and investigating 25 days after application; spraying at the early stage of tomato gray mold generation, applying the pesticide twice at intervals of 7 days, and investigating 15 days after the pesticide application; spraying at the early stage of tomato sclerotiniose occurrence, applying the pesticide twice at intervals of 7 days, and investigating 15 days after the pesticide application; spraying twice at 7 days intervals at the early gray mold of eggplant, and investigating 15 days after the spraying, and spraying twice at 7 days intervals at 15 days intervals at the early gray mold of pepper; spraying twice at 7 days intervals at the initial stage of the capsicum sclerotinia sclerotiorum, and investigating 15 days after the application; see tables 4-14 below for results.
The single-dose preparation and the compound preparation used for preventing and treating each disease have the same dosage form, and are generally suspending agents. The formulation is not the key for verifying the synergistic effect of the compound preparation, the preparation sometimes needs to be adjusted according to actual crops and diseases, but the formulation used in all experiments aiming at each disease is the same regardless of the adjustment, and the auxiliary agent is not changed except for the change of the active ingredients so as to ensure the consistency of the active ingredients.
According to the efficacy evaluation mode of the Gowing method, the calculation formula is as follows: e0X + Y (100-X)/100, wherein X is A single-agent control effect (%), Y is B single-agent control effect (%), E is A, B actual control effect (%) of two single-agents in a mixed mode, and when E-E is used0>10 hours is synergistic, E-E0<10 hours is a decrease, E-E0An additive effect is obtained when the concentration is within +/-10.
Table 4: field efficacy test of different compound agents for preventing and treating strawberry gray mold
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment for preventing and treating the gray mold of the strawberry with a single agent is carried out, the actual prevention effect is more than 10 times greater than the theoretical prevention effect, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic prevention and treatment for the gray mold of the strawberry.
Table 5: field efficacy test of different compound agents for preventing and treating cucumber powdery mildew
| Serial number | Effective ingredient application dose (g/hectare) | Index of disease condition | Actual control effect (%) | Theoretical control effect (%) |
| 1 | Biphenyl pyrazinamide (2) | 61.17 | 15.43 | -- |
| 2 | Biphenyl pyrazinamide (45) | 35.30 | 51.2 | -- |
| 3 | Biphenyl pyrazinamide (50) | 30.16 | 58.3 | -- |
| 4 | Fluazinam (40) | 41.71 | 42.34 | -- |
| 5 | Boscalid (15) | 47.75 | 33.98 | -- |
| 6 | Prothioconazole (5) | 63.32 | 12.45 | -- |
| 7 | Biphenyl pyrazinamide + fluazinam 1:20(2+40) | 22.60 | 68.76 | 51.24 |
| 8 | Biphenyl pyrazinamide + prothioconazole 3:1(45+15) | 15.51 | 78.56 | 67,78 |
| 9 | Biphenyl pyrazinamide + boscalid 10:1(50+5) | 9.73 | 86.55 | 63.49 |
| 10 | CK (Water) | 72.33 | -- | -- |
The synergistic comparison of the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the single-agent treatment room for controlling the powdery mildew of cucumbers is carried out, the actual control effects are all more than 10 greater than the theoretical control effect, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic control of the powdery mildew of the cucumbers.
Table 6: field efficacy test of different compound agents for preventing and treating cucumber sclerotinia rot
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment room for controlling the cucumber sclerotinia by using a single agent is carried out, the actual control effects are all more than 10 greater than the theoretical control effects, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic control of the cucumber sclerotinia.
Table 7: field efficacy test of different compound agents for preventing and treating cucumber gray mold
| Serial number | Effective component and application dose (g/hectare) | Index of disease condition | Actual control effect (%) | Theoretical control effect (%) |
| 1 | Biphenyl pyrazinamide (40) | 32.95 | 58.44 | -- |
| 2 | Biphenyl pyrazinamide (10) | 53.67 | 32.30 | -- |
| 3 | Biphenyl pyrazinamide (1) | 57.30 | 27.72 | -- |
| 4 | Fluazinam (2) | 59.79 | 24.58 | -- |
| 5 | Boscalid (30) | 46.69 | 41.11 | -- |
| 6 | Prothioconazole (40) | 41.85 | 47.21 | -- |
| 7 | Biphenyl pyrazinamide + fluazinam 20:1(40+2) | 11.45 | 85.56 | 68.66 |
| 8 | Biphenyl pyrazinamide + prothioconazole 1:3(10+30) | 16.38 | 79.34 | 60.13 |
| 9 | Biphenyl pyrazinamide + boscalid 1:40(1+40) | 22.49 | 71.63 | 61.84 |
| 10 | CK (Water) | 79.28 | -- | -- |
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment of preventing and treating the gray mold of the cucumber with a single agent is carried out, the actual prevention effect is more than 10 times greater than the theoretical prevention effect, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic prevention and treatment of the gray mold of the cucumber.
Table 8: field efficacy test of different compound agents for preventing and treating strawberry powdery mildew
| Serial number | Effective ingredient application dose (g/hectare) | Index of disease condition | Actual control effect (%) | Theoretical control effect (%) |
| 1 | Biphenyl pyrazinamide (2) | 44.58 | 22.60 | -- |
| 2 | Biphenyl pyrazinamide (45) | 26.15 | 54.60 | -- |
| 3 | Biphenyl pyrazinamide (50) | 28.49 | 50.54 | -- |
| 4 | Fluazinam (40) | 28.71 | 50.14 | -- |
| 5 | Boscalid (15) | 37.02 | 35.72 | -- |
| 6 | Prothioconazole (5) | 42.11 | 26.88 | -- |
| 7 | Biphenyl pyrazinamide + fluazinam 1:20(2+40) | 9.10 | 84.20 | 61.41 |
| 8 | Biphenyl pyrazinamide + prothioconazole 3:1(45+15) | 7.05 | 87.76 | 70.82 |
| 9 | Biphenyl pyrazinamide + boscalid 10:1(50+5) | 8.93 | 84.49 | 63.83 |
| 10 | CK (Water) | 57.59 | --- | -- |
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment room for preventing and treating the strawberry powdery mildew with a single agent is carried out, the actual prevention effect is more than 10 times greater than the theoretical prevention effect, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic prevention and treatment of the strawberry powdery mildew.
Table 9: field efficacy test of different compound agents for preventing and treating Chinese cabbage sclerotinia rot
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment of single-dose preventing and treating Chinese cabbage sclerotinia is carried out, the actual preventing and treating effects are all more than 10 greater than the theoretical preventing and treating effects, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic preventing and treating of the Chinese cabbage sclerotinia.
Table 10: field efficacy test of different compound agents for preventing and treating tomato gray mold
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment of preventing and treating the gray mold of the tomatoes with a single dose is carried out, the actual prevention effect is more than 10 times greater than the theoretical prevention effect, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic prevention and treatment of the gray mold of the tomatoes.
Table 11: field efficacy test of different compound agents for preventing and treating tomato sclerotinia rot
| Serial number | Effective ingredient application dose (g/hectare) | Index of disease condition | Actual control effect (%) | Theoretical control effect (%) |
| 1 | Biphenyl pyrazinamide (40) | 30.41 | 51.96 | -- |
| 2 | Biphenyl pyrazinamide (20) | 42.93 | 32.18 | -- |
| 3 | Biphenyl pyrazinamide (5) | 48.96 | 22.65 | -- |
| 4 | Fluazinam (5) | 55.55 | 12.24 | -- |
| 5 | Boscalid (20) | 37.16 | 41.28 | -- |
| 6 | Prothioconazole (40) | 41.48 | 34.46 | -- |
| 7 | Biphenyl pyrazinamide + fluazinam 8:1(40+5) | 9.88 | 84.39 | 57.84 |
| 8 | Biphenyl pyrazinamide + prothioconazole 1:1(20+20) | 13.00 | 79.45 | 60.18 |
| 9 | Biphenyl pyrazinamide + boscalid 1:8(5+40) | 15.45 | 75.59 | 49.30 |
| 10 | CK (Water) | 63.29 | --- | -- |
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment room for preventing and treating the tomato sclerotinia with a single dose is carried out, the actual prevention effect is more than 10 times greater than the theoretical prevention effect, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic prevention and treatment of the tomato sclerotinia.
Table 12: field efficacy test of different compound agents for controlling gray mold of eggplant
| Serial number | Effective component and application dose (g/hectare) | Index of disease condition | Actual control effect (%) | Theoretical control effect (%) |
| 1 | Biphenyl pyrazinamide (40) | 34.98 | 49.86 | -- |
| 2 | Biphenyl pyrazinamide (10) | 46.24 | 33.72 | -- |
| 3 | Biphenyl pyrazinamide (1) | 49.44 | 29.13 | -- |
| 4 | Fluazinam (2) | 52.62 | 24.58 | -- |
| 5 | Boscalid (30) | 44.08 | 36.82 | -- |
| 6 | Prothioconazole (40) | 48.80 | 30.05 | -- |
| 7 | Biphenyl pyrazinamide + fluazinam 20:1(40+2) | 12.07 | 82.70 | 62.18 |
| 8 | Biphenyl pyrazinamide + prothioconazole 1:3(10+30) | 13.41 | 80.78 | 58.12 |
| 9 | Biphenyl pyrazinamide + boscalid 1:40(1+40) | 15.80 | 77.36 | 50.43 |
| 10 | CK (Water) | 69.77 | --- | -- |
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment for controlling the gray mold of the eggplant with a single dose is carried out, the actual control effects are all more than 10 greater than the theoretical control effect, and the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid can realize the synergistic control of the gray mold of the eggplant.
Table 13: field efficacy test of different compound agents for preventing and treating gray mold of capsicum
| Serial number | Effective component and application dose (g/hectare) | Index of disease condition | Actual control effect (%) | Theoretical control effect (%) |
| 1 | Biphenyl pyrazinamide (40) | 34.92 | 49.11 | -- |
| 2 | Biphenyl pyrazinamide (10) | 47.44 | 30.86 | -- |
| 3 | Biphenyl pyrazinamide (1) | 49.00 | 28.58 | -- |
| 4 | Fluazinam (2) | 58.54 | 14.68 | -- |
| 5 | Boscalid (30) | 43.03 | 37.28 | -- |
| 6 | Prothioconazole (40) | 44.29 | 35.45 | -- |
| 7 | Biphenyl pyrazinamide + fluazinam 20:1(40+2) | 17.42 | 74.61 | 56.58 |
| 8 | Biphenyl pyrazinamide + prothioconazole 1:3(10+30) | 19.92 | 70.97 | 56.64 |
| 9 | Biphenyl pyrazinamide + boscalid 1:40(1+40) | 18.57 | 72.93 | 53.90 |
| 10 | CK (Water) | 68.61 | --- | -- |
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the treatment of preventing and treating the gray mold of the pepper with a single agent is carried out, the actual prevention effect is more than 10 times greater than the theoretical prevention effect, and the synergistic prevention and treatment of the gray mold of the pepper can be realized by the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid.
Table 14: field efficacy test of different compound agents for preventing and treating capsicum sclerotium disease
The synergistic comparison between the compound preparation of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid and the single-dose treatment for preventing and treating the capsicum sclerotinia is carried out, the actual prevention effect is more than 10 times greater than the theoretical prevention effect, and the synergistic prevention and treatment of the capsicum sclerotinia can be realized by the compound composition of the biphenylpyrazinamide and the fluazinam, the prothioconazole and the boscalid.
Claims (11)
1. The bactericidal composition is characterized by comprising a bactericidal active ingredient A and a bactericidal active ingredient B, wherein the bactericidal active ingredient A is a compound shown as the following formula (I):
the bactericidal active ingredient B is prothioconazole, and the weight ratio of the bactericidal active ingredient A to the bactericidal active ingredient B is 80:1, 1:80 or 9: 1.
2. The bactericidal composition of claim 1, wherein the sum of the weight of bactericidal active ingredient a and bactericidal active ingredient B is 1-70% of the weight of the bactericidal composition.
3. The bactericidal composition according to any one of claims 1 to 2, wherein the bactericidal composition comprises a third bactericidal component, the third bactericidal component is one selected from the group consisting of amide bactericides, dicarboximide bactericides, triazole bactericides, imidazole bactericides, oxazole bactericides, thiazole bactericides, morpholine bactericides, pyrrole bactericides, pyridine bactericides, pyrimidine bactericides, quinazolinone bactericides, carbamate bactericides, organophosphorus bactericides, thiocarbamate bactericides, copper preparations, and mercury bactericides, and the third bactericidal component accounts for 1 to 50 wt% of the bactericidal composition.
4. The bactericidal composition according to any one of claims 1-2, wherein the bactericidal composition comprises a pesticide carrier and a pesticide adjuvant, the sum of the weight of the pesticide carrier and the pesticide adjuvant accounts for 1-90% of the weight of the bactericidal composition, the pesticide carrier is a liquid carrier or a solid carrier, and the pesticide adjuvant is one or more selected from the group consisting of an emulsifier, a dispersant, a wetting agent, a thickener, an antifoaming agent, an oxidant, an antifreezing agent and a disintegrant.
5. The bactericidal composition according to any one of claims 1-2, wherein the bactericidal composition is prepared into a composition preparation which is an emulsifiable concentrate, a suspending agent, a water dispersible granule, an aqueous emulsion, a microemulsion, a soluble liquid agent, a wettable powder, an oil suspending agent, a suspended seed coating agent or a granule.
6. The application of the bactericidal composition is to control plant diseases, wherein the plant diseases are ginseng sclerotinia rot, Chinese cabbage sclerotinia rot, strawberry gray mold, strawberry powdery mildew, cucumber gray mold, cucumber sclerotinia rot, tomato gray mold, tomato sclerotinia rot, eggplant gray mold, pepper gray mold or pepper sclerotinia rot, the bactericidal composition comprises a bactericidal active ingredient A and a bactericidal active ingredient B, and the bactericidal active ingredient A is a compound shown in the following formula (I):
the bactericidal active ingredient B is prothioconazole, and the weight ratio of the bactericidal active ingredient A to the bactericidal active ingredient B is 1:80 to 80: 1.
7. Use according to claim 6, characterized in that the weight ratio of the bactericidal active ingredient A to prothioconazole is 1:3, 3:1 or 1: 1.
8. Use according to any one of claims 6 to 7, characterized in that the sum of the weight of the bactericidal active ingredient A and the bactericidal active ingredient B represents 1 to 70% by weight of the bactericidal composition.
9. The use according to any one of claims 6 to 7, characterized in that the bactericidal composition comprises a third bactericidal component, the third bactericidal component is one selected from amide bactericides, dicarboximide bactericides, triazole bactericides, imidazole bactericides, oxazole bactericides, thiazole bactericides, morpholine bactericides, pyrrole bactericides, pyridine bactericides, pyrimidine bactericides, quinazolinone bactericides, carbamate bactericides, organophosphorus bactericides, thiocarbamate bactericides, copper preparations and mercury bactericides, and the third bactericidal component accounts for 1 to 50 percent of the weight of the bactericidal composition.
10. The use according to any one of claims 6 to 7, characterized in that the bactericidal composition comprises a pesticide carrier and a pesticide adjuvant, the sum of the weight of the pesticide carrier and the pesticide adjuvant accounts for 1 to 90 percent of the weight of the bactericidal composition, the pesticide carrier is a liquid carrier or a solid carrier, and the pesticide adjuvant is selected from one or more of an emulsifier, a dispersant, a wetting agent, a thickener, an antifoaming agent, an oxidant, an antifreezing agent and a disintegrant.
11. A method for controlling plant diseases by applying the fungicidal composition according to any one of claims 1 to 2, in a fungicidally effective amount to the stem and leaf parts, roots or plant seeds by spraying, root application or seed coating, wherein the plant diseases are ginseng sclerotinia, cabbage sclerotinia, strawberry gray mold, strawberry powdery mildew, cucumber gray mold, cucumber sclerotinia, tomato gray mold, tomato sclerotinia, eggplant gray mold, pepper gray mold or pepper sclerotinia.
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