CN107847441B - 用于递送亲脂性化合物的纳米胶囊及其制备方法 - Google Patents

用于递送亲脂性化合物的纳米胶囊及其制备方法 Download PDF

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CN107847441B
CN107847441B CN201680042159.7A CN201680042159A CN107847441B CN 107847441 B CN107847441 B CN 107847441B CN 201680042159 A CN201680042159 A CN 201680042159A CN 107847441 B CN107847441 B CN 107847441B
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capsules
oil
nanocapsule
chitosan
sulfate
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CN107847441A (zh
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斯切泽攀·扎帕特科兹尼
乔安娜·斯扎弗莱尼克
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Poland Garde Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5176—Compounds of unknown constitution, e.g. material from plants or animals

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201680042159.7A 2015-07-17 2016-07-12 用于递送亲脂性化合物的纳米胶囊及其制备方法 Active CN107847441B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PLP.413155 2015-07-17
PL413155A PL229276B1 (pl) 2015-07-17 2015-07-17 Nanokapsuła do przenoszenia związku lipofilowego i sposób jej wytwarzania
PCT/PL2016/050032 WO2017014655A1 (en) 2015-07-17 2016-07-12 Nanocapsule for delivery of lipophilic compound and process of preparation thereof

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CN107847441A CN107847441A (zh) 2018-03-27
CN107847441B true CN107847441B (zh) 2021-08-13

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US (2) US10821083B2 (enExample)
EP (1) EP3324939A1 (enExample)
JP (1) JP6971217B2 (enExample)
KR (1) KR20180025318A (enExample)
CN (1) CN107847441B (enExample)
AU (3) AU2016295949A1 (enExample)
CA (1) CA2992705A1 (enExample)
MX (1) MX387005B (enExample)
PL (1) PL229276B1 (enExample)
RU (1) RU2723374C1 (enExample)
WO (1) WO2017014655A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018176047A (ja) * 2017-04-10 2018-11-15 パナソニックＩｐマネジメント株式会社 マイクロカプセル及びマイクロカプセルの製造方法、並びに、化粧料及び化粧料の製造方法
CN109535430A (zh) * 2017-09-22 2019-03-29 天津大学 一种油酰化壳寡糖胍接枝聚乙烯亚胺的两亲性衍生物及其制备方法
ES2711669A1 (es) * 2017-11-02 2019-05-06 Univ Santiago Compostela Sistemas de liberacion de farmacos de acido polisialico y metodos
CN108246215B (zh) * 2017-12-21 2020-06-30 四川大学 一种超薄壁壳聚糖微囊及其制备方法
PL240632B1 (pl) * 2018-04-06 2022-05-09 Univ Jagiellonski Zastosowanie nanokapsuły z ciekłym rdzeniem olejowym w terapii przeciwnowotworowej
CN108739807B (zh) * 2018-06-21 2021-07-13 中国热带农业科学院农产品加工研究所 植物油酸-壳聚糖基纳米微胶囊农药、其制备方法及其应用
CN112888428A (zh) * 2018-08-17 2021-06-01 克里兹托夫·斯梅拉 包封亲脂和亲水性化合物的纳米胶囊包纳米胶囊型的多隔室体系及相关生产方法
CN109925983B (zh) * 2019-03-08 2021-12-28 紫罗兰家纺科技股份有限公司 基于乳木果油的双层微胶囊及其整理到纺织面料中的方法
CN111920782B (zh) * 2019-05-13 2025-11-18 中国医学科学院药物研究所 复合脂质纳米囊组合物及其制备方法和应用
CN112300767B (zh) * 2020-09-22 2022-04-05 山东大学 一种绿色靶向微胶囊及制备体系、制备方法和应用
EP4321175B1 (en) 2022-08-11 2025-07-16 CHDE Polska S.A. Magnetic polymer nanocapsules suitable for use in therapy, especially anti-cancer ones
PL446441A1 (pl) * 2023-10-20 2025-04-22 Chde Polska Spółka Akcyjna 2-metylo-3-fitylo-1,4-naftochinon do stosowania w leczeniu lub zapobieganiu chorób przebiegających z dysfunkcją śródbłonka naczyniowego

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101410098A (zh) * 2006-01-23 2009-04-15 耶路撒冷希伯来大学伊森姆研究发展公司 包括含亲脂性药物的纳米胶囊的微球
CN101426479A (zh) * 2006-03-13 2009-05-06 先进离体细胞技术有限公司 用于活性分子给药的稳定的纳米胶囊体系
CN102161729A (zh) * 2011-02-25 2011-08-24 上海交通大学 水溶性多糖与疏水性单体形成纳米粒子的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2093562B1 (es) 1995-05-26 1997-07-01 Univ Santiago Compostela Estabilizacion de sistemas coloidales mediante formacion de complejos ionicos lipido-polisacarido.
US20060063676A1 (en) 2004-09-17 2006-03-23 Brigance Mickey R Method for enhancing deposition of an agrochemical
CA2618974C (en) 2005-08-09 2014-01-28 Nanobio Corporation Nanoemulsion compositions having anti-inflammatory activity
EP2266546A1 (en) 2009-06-08 2010-12-29 Advancell Advanced in Vitro Cell Technologies,S.A. Process for the preparation of colloidal systems for the delivery of active compounds
ES2366255B2 (es) 2011-06-27 2012-08-08 Universidade De Santiago De Compostela Nanocomposiciones sacarídicas para la liberación de vacunas.
RU2494728C1 (ru) 2012-08-16 2013-10-10 Федеральное государственное унитарное предприятие "Государственный научный центр "Научно-исследовательский институт органических полупродуктов и красителей" (ФГУП "ГНЦ "НИОПИК") Наноэмульсия, содержащая биологически активное вещество
CZ304654B6 (cs) * 2012-11-27 2014-08-20 Contipro Biotech S.R.O. Nanomicelární kompozice na bázi C6-C18-acylovaného hyaluronanu, způsob přípravy C6-C18-acylovaného hyaluronanu, způsob přípravy nanomicelární kompozice a stabilizované nanomicelární kompozice a použití
JP2016531112A (ja) 2013-07-25 2016-10-06 ネムコア メディカル イノベーションズ インコーポレイテッド 疎水性白金誘導体のナノエマルジョン

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101410098A (zh) * 2006-01-23 2009-04-15 耶路撒冷希伯来大学伊森姆研究发展公司 包括含亲脂性药物的纳米胶囊的微球
CN101426479A (zh) * 2006-03-13 2009-05-06 先进离体细胞技术有限公司 用于活性分子给药的稳定的纳米胶囊体系
CN102161729A (zh) * 2011-02-25 2011-08-24 上海交通大学 水溶性多糖与疏水性单体形成纳米粒子的制备方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
Hongqiang Wang et al.Sono-Assembly of Highly Biocompatible Polysaccharide Capsules for Hydrophobic Drug Delivery.《Advanced Healthcare Materials》.2014,第3卷(第6期), *
Nanoparticles Based on Modified Polysaccharides;Hassan Namazi et al;《The Delivery of Nanoparticles》;20120516;第1-2页 *
Sono-Assembly of Highly Biocompatible Polysaccharide Capsules for Hydrophobic Drug Delivery;Hongqiang Wang et al;《Advanced Healthcare Materials》;20140601;第3卷(第6期);第1-7页 *

Also Published As

Publication number Publication date
WO2017014655A1 (en) 2017-01-26
MX2018000637A (es) 2018-09-06
CN107847441A (zh) 2018-03-27
AU2016295949A1 (en) 2018-02-01
PL413155A1 (pl) 2017-01-30
RU2723374C1 (ru) 2020-06-10
AU2024201288A1 (en) 2024-03-14
US20180200197A1 (en) 2018-07-19
EP3324939A1 (en) 2018-05-30
US20200345651A1 (en) 2020-11-05
MX387005B (es) 2025-03-12
PL229276B1 (pl) 2018-06-29
CA2992705A1 (en) 2017-01-26
AU2021240279A1 (en) 2021-10-28
US10821083B2 (en) 2020-11-03
JP2018523642A (ja) 2018-08-23
KR20180025318A (ko) 2018-03-08
HK1251154A1 (zh) 2019-01-25
JP6971217B2 (ja) 2021-11-24

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