CN107823630A - 治疗癌症的方法 - Google Patents

治疗癌症的方法 Download PDF

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Publication number
CN107823630A
CN107823630A CN201711171931.8A CN201711171931A CN107823630A CN 107823630 A CN107823630 A CN 107823630A CN 201711171931 A CN201711171931 A CN 201711171931A CN 107823630 A CN107823630 A CN 107823630A
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fgfr1
cancer
ecd
cell
fgfr1ecd
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CN201711171931.8A
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Chinese (zh)
Inventor
T·哈丁
S·帕伦希亚
L·朗
K·赫斯迪尔
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Five Prime Therapeutics Inc
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Five Prime Therapeutics Inc
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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  • Organic Chemistry (AREA)
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CN201711171931.8A 2011-11-14 2012-11-13 治疗癌症的方法 Pending CN107823630A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161559259P 2011-11-14 2011-11-14
US61/559,259 2011-11-14
US201261616761P 2012-03-28 2012-03-28
US61/616,761 2012-03-28
CN201280066268.4A CN104168915A (zh) 2011-11-14 2012-11-13 治疗癌症的方法

Related Parent Applications (1)

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CN107823630A true CN107823630A (zh) 2018-03-23

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CN201280066268.4A Pending CN104168915A (zh) 2011-11-14 2012-11-13 治疗癌症的方法

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US (3) US20130136740A1 (enExample)
EP (1) EP2780033B1 (enExample)
JP (2) JP2015505818A (enExample)
CN (2) CN107823630A (enExample)
AU (1) AU2012318247B2 (enExample)
CA (1) CA2855818A1 (enExample)
HK (2) HK1202240A1 (enExample)
TW (1) TW201326201A (enExample)
WO (1) WO2013074492A1 (enExample)

Cited By (3)

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Publication number Priority date Publication date Assignee Title
CN109609640A (zh) * 2019-01-14 2019-04-12 中国科学院上海高等研究院 Etv4的用途
CN111735950A (zh) * 2020-07-17 2020-10-02 北京信诺卫康科技有限公司 Fgf18和ca125联合用作早期卵巢癌生物标志物以及试剂盒
CN111912987A (zh) * 2020-08-25 2020-11-10 北京信诺卫康科技有限公司 Fgf18和he4联合用作早期卵巢癌生物标志物以及试剂盒

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US8614183B2 (en) 2009-11-13 2013-12-24 Five Prime Therapeutics, Inc. Use of FGFR1 extra cellular domain proteins to treat cancers characterized by ligand-dependent activating mutations in FGFR2
US8481038B2 (en) 2010-11-15 2013-07-09 Five Prime Therapeutics, Inc. Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
US8951972B2 (en) 2010-12-09 2015-02-10 Five Prime Therapeutics, Inc. FGFR1 extracellular domain combination therapies for lung cancer
CN107823630A (zh) 2011-11-14 2018-03-23 戊瑞治疗有限公司 治疗癌症的方法
TWI718086B (zh) 2013-01-07 2021-02-11 英屬維爾京群島商遠東超級實驗室有限公司 通過干擾素的經皮和/或經粘膜給藥治療骨癌、皮膚癌、皮下癌、粘膜癌和/或粘膜下癌的方法和組合物
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CN107847564B (zh) * 2015-05-12 2021-11-09 远东超级实验室有限公司 鉴定对肿瘤具有直接抑制作用的干扰素的方法及其用途
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109609640A (zh) * 2019-01-14 2019-04-12 中国科学院上海高等研究院 Etv4的用途
CN111735950A (zh) * 2020-07-17 2020-10-02 北京信诺卫康科技有限公司 Fgf18和ca125联合用作早期卵巢癌生物标志物以及试剂盒
CN111735950B (zh) * 2020-07-17 2023-07-21 北京信诺卫康科技有限公司 Fgf18和ca125联合用作早期卵巢癌生物标志物以及试剂盒
CN111912987A (zh) * 2020-08-25 2020-11-10 北京信诺卫康科技有限公司 Fgf18和he4联合用作早期卵巢癌生物标志物以及试剂盒
CN111912987B (zh) * 2020-08-25 2023-07-21 北京信诺卫康科技有限公司 Fgf18和he4联合用作早期卵巢癌生物标志物以及试剂盒

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