CN107802568A - A kind of oral cavity cleaning and nursing liquid of CRHD activity and preparation method thereof - Google Patents
A kind of oral cavity cleaning and nursing liquid of CRHD activity and preparation method thereof Download PDFInfo
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- CN107802568A CN107802568A CN201711211191.6A CN201711211191A CN107802568A CN 107802568 A CN107802568 A CN 107802568A CN 201711211191 A CN201711211191 A CN 201711211191A CN 107802568 A CN107802568 A CN 107802568A
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- parts
- gel
- oral cavity
- nursing liquid
- crhd
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/347—Phenols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/43—Guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Abstract
A kind of oral cavity cleaning and nursing liquid of CRHD activity and preparation method thereof, the invention belongs to oral cavity sterilizing product, a kind of less toxic pair, enriching yin clearing damp, readily soluble water, infiltration be strong, free from extraneous odour, safe and simple gargle to provide, and the technical scheme of oral cavity cleaning and nursing liquid offer of the present invention is：2 ~ 6 parts of gluconic acid chlorhexidine, 3 ~ 25 parts of promise Buddhist nun's ethanol gel, 1 ~ 5 part of thymol, 3 ~ 15 parts of papain gel, aloe gel 1:1 ~ 5 part, 0.5 5 parts of calcium hydroxide, 1 ~ 6 part of boric acid, 10 ~ 20 parts of sodium chloride, CRHD deionized water surpluses.Oral cavity of the present invention cleaning and nursing liquid has the function that antibacterial, anti-inflammatory in the oral cavity, removes dental pulp, improves the dissipation ability of pathogenic microorganism mucous membrane vitamin malignant bacteria in human oral cavity, optimize mucous membrane of mouth immuning tissue function, cure canker sore, various focusing depths represented, go to eliminate the unusual smell and other effects.Oral cavity of the present invention cleaning and nursing liquid safety, it is that market potential is huge with the environmentally friendly health-oriented products of consumers.
Description
Technical field
The invention belongs to oral cavity sterilizing product, and in particular to a kind of morinda citrifolia ethanol based on CRHD activity carries
Thing is taken, tooth tube wall pollution layer can be dispelled, cleans the oral cavity cleaning and nursing liquid of dental pulp.
Background technology
Science and technology and economic fast development, the rapid raising of social civilization and health perception, make the health of people's counterpart chamber
Nursing, cleaning and health care focus more on.Oral cavity is that food enters gastral important channel, and multiple-microorganism is lived away from home and bacterium
The particular surroundings of growth.Substantial amounts of beneficial and malignant bacteria is generally there are in " illness finds its way in by the mouth " oral cavity.The people of health is led to daily
Drinking-water feed, the activity such as gargle of brushing teeth are crossed, body immune system can be made to play anti-inflammatory sterilization, metabolic balance effect, maintenance function
Health.When people are with major disease or tired in Bad habits are in sub-health state, body autoimmune function declines
When, the microorganism remained in tooth pipe or the source of infection of dental pulp and intraoral pathogenic bacteria can amount reproduction, cause oral cavity it is unclean,
The symptoms such as inflammation, peculiar smell, canker sore, various focusing depths represented mouth disease.Oral cavity is the window of health, and " sense of taste conditioned reflex is with being good for
Health identification " CRHD can determine whether the health status of human body.China human mortality is numerous, the huge market demand, in recent years personal oral cleaning shield
The R＆D and production of reason product has reached 45% speedup, is focused more on attention by consumers in general, brand competition is further fierce.
Traditional oral cleaning-nursing liquid is such as：Physiological saline, sodium acid carbonate oral liquid, sodium chloride, potassium nitrate, peroxidating oxygen are molten
Liquid, or medical product is such as：Chlorohexidene, first nitre file etc., non-direct oral cavity doctor and dentist instruct, long-term use of function of not suiting the medicine to the illness
The single oral care product for having side effect, can also bring harm, make tooth stain be deposited on dental surface, influence the sense of taste, cause mouth
Intracavitary flora is unbalance, and the sense of the taste bud sense of taste reduces, and sensitivity of tooth degree lowers, and causes the malaise symptoms such as the dry, cusalgia of dry, tongue.Using
Normal saline solution carries out dentilave nursing, can form hypertonic solution after aqueous medium evaporation, sodium chloride material is collected at oral cavity
On mucous membrane tissue, periodontium is damaged, the inflammation such as mucosa hemorrhage occur.Therefore being capable of the fresh breath, beauty that takes care of one's teeth, right
Multiple oral disease have treatment, health-care effect, have to oral peculiar smell it is quick remove function, in a variety of contexts can safe ready
The oral-cavity cleaning products that fashion uses, it can all be favored by Market Consumer.
Morinda citrifolia（Nuo Ni）Contain aucubin, L2 asperulosides alizarin and anthraquinone compounds in fruit juice, can be effective
Prevent green pus vacation simple unicellular bacteria, mycetozoan, staphylococcus aureus, rod bacterium, Escherichia coli, detection of Salmonella and bacillus dysenteriae etc.
The infection of cell.These active antibacterial ingredients to treatment alleviate flu, heating, various focusing depths represented, canker sore, skin infection and its
He has significant curative effect because of bacterial disease.The ethanol extract of promise Buddhist nun can increase the shrinkage factor of wound ulcer, convergence
Energy and anti-microbial property, dental pulp is cleaned, the weight of the pollution of tooth lip wall, epithelium rate and the granulation tissue generated is removed, according to tradition
Tcm theory, Nuo Ni（Morinda citrifolia）With from the microcosmic equilibrium between yin and yang that human body is reconciled to macroscopic view, and to many different
Health problem（Disease）It is helpful so that its can have been given play in a different manner from a kind of single plant it is different
Effect.
CRHD（Based on human body " sense of taste conditioned reflex and health identification "）Structural system
“Conditional Reflex and Health Diagnostic based on taste”
Tested using the human body sense of taste to assess the structural system of human body health status, and obtained according to medical science and physiology promise prize
Person has found：" only small-micelle water could pass through 2 nanometers（nm）Human body cell ion channel, into nucleus and DNA, swash
Send out vitality, common pure water macromolecular mass can not be directly entered into the cell " discovery, prepared active water（Deionization
Water）.Ectoenzyme caused by mineral matter group in CRHD solution can effectively decompose the organic substance in thimerosal, and utilize release
The unique absorption property gone out promotes activation to optimize the beneficiating ingredients such as the skin care in disinfectant, sterilization, antibacterial, anti-inflammatory.It is environment-friendly
Type, antibacterial wide spectrum, quick-acting, bactericidal action is lasting；Less toxic pair, enriching yin clearing damp, readily soluble water, infiltration by force, it is free from extraneous odour, safe and simple,
It is preferred oral cavity cleaning and nursing class product market has been turned into.
The content of the invention
Offer of the invention is a kind of to remove tooth tube wall pollution layer, cleaning dental pulp, optimizes human oral cavity mucosa-immune tissue, be effective
The organic substance for making one easily to absorb in oral nursing liquid is decomposed, it is environmentally friendly, in a variety of environmental conditions, all conveniently make
With safe and simple, fashion oral cavity cleaning and nursing product.
The present invention is according to small in CRHD human bodies " sense of taste conditioned reflex identifies with health " principle and the CRHD modification aqueous solution
Molecule group beam（HZ）Ectoenzyme caused by mineral matter group can effectively decompose the active material Thief zone in mouth care solution
The characteristic such as attribute, absorption of human body of being more convenient for, rational proportion, overcome traditional oral care product make oral cavity flora imbalance, it is unbalance,
Antibacterial, anti-inflammatory effect deficiency, improve dissipation of the care agent to pathogenic microorganism mucous membrane vitamin malignant bacteria in human oral cavity
Function, mucous membrane of mouth immuning tissue is obtained healthy optimization, have to the treatment multiple oral disease such as canker sore and various focusing depths represented
Therapeutic action.
The present invention is accomplished in the following manner：Oral cavity cleaning and nursing liquid of the present invention, by the raw material group of following parts by weight
Into：2 ~ 6 parts of gluconic acid chlorhexidine, 3 ~ 25 parts of promise Buddhist nun's ethanol gel, 1 ~ 5 part of thymol, 3 ~ 15 parts of papain gel,
Aloe gel 1:1 ~ 5 part, calcium hydroxide 0.5-5 parts, 1 ~ 6 part of boric acid, 10 ~ 20 parts of sodium chloride, CRHD deionized water surpluses.Described
Promise Buddhist nun's ethanol gel is after being extracted using 75% ethanol, to remove the gel that ethanol obtains.
Oral cavity of the present invention cleaning and nursing liquid, preferably match the raw material composition of following parts by weight：Gluconic acid chlorhexidine 3
Part, 6 parts of promise Buddhist nun's ethanol gel, 2 parts of thyme, 5 parts of papain gel, 3 parts of aloe gel, 5 parts of calcium hydroxide, boric acid 6
Part, 15 parts of sodium chloride.
The preparation method of oral cavity of the present invention cleaning and nursing liquid, is prepared by following technique：Weigh the original of said ratio
Material, by gluconic acid chlorhexidine and promise Buddhist nun's ethanol gel, papain gel, aloe gel mixing 15 ~ 25 minutes, then by musk deer
Vanilla phenol is added in said mixture, is mixed 15 ~ 30 minutes, is eventually adding boric acid, sodium chloride and calcium hydroxide and is mixed into wherein, then
Mixture is added into 5000ml small molecules deionized water dissolving, filtering by proportioning, produced；Through 100 DEG C ~ 120 DEG C boiling water sterilizings one
Hour, filling 50ml/ branch, Different Package type " safe and simple oral cavity cleaning and nursing liquid " is made.
The preparation method of oral cavity of the present invention cleaning and nursing liquid, optimal preparation method are prepared by following technique：Weigh
The raw material of said ratio, by gluconic acid chlorhexidine and promise Buddhist nun's ethanol gel, papain gel, aloe gel, mixing 25
Minute, then thymol is added in said mixture, mix 20 minutes, be eventually adding boric acid, sodium chloride and calcium hydroxide mix
Close uniformly, add 5000ml small molecule deionized water dissolvings by proportioning after placing 30 minutes, filter and produce；Through 100 DEG C ~ 120 DEG C
Boiling water sterilizes one hour, filling 50ml/ branch, Different Package type system " safe and simple oral cavity cleaning and nursing liquid " is made.
Oral cavity of the present invention has antibacterial, anti-inflammatory with cleaning and nursing liquid, removes tooth tube wall pollution layer in the oral cavity, removes tooth
Marrow, improve the dissipation ability of pathogenic microorganism mucous membrane vitamin malignant bacteria in human oral cavity, optimization mucous membrane of mouth immuning tissue
Function, cures canker sore, various focusing depths represented, go to eliminate the unusual smell and other effects.Oral cavity of the present invention cleaning and nursing liquid, it is safe, portable, wide
Spectrum, efficiently, is that market potential is huge with the environmentally friendly health-oriented products of consumers.
Embodiment
Embodiment 1
（1）Raw material is weighed according to proportioning：Gluconic acid chlorhexidine 2g, promise Buddhist nun's ethanol gel 20g, thymol 3g, Papain
Enzyme gel 8g, aloe gel 4g, calcium hydroxide 5g, boric acid 4g, 10 ~ 20g of sodium chloride, appropriate deionized water；（2）By gluconic acid
Chlorhexidine, promise Buddhist nun's ethanol gel, papain gel and aloe gel are mixed 25 minutes, then thymol is added into above-mentioned mix
In compound, mix 15 minutes；（3）Add boric acid, sodium chloride and calcium hydroxide to be added thereto, then mixture is added by proportioning
5Kg deionized water dissolvings, filtering；（4）Sterilized one hour through 110 DEG C of boiling water, it is filling to obtain oral nursing liquid.
Embodiment 2
Weigh gluconic acid and determine 5g, promise Buddhist nun's ethanol gel 25g, thymol 3g, papain gel 15g, aloe gel
5g, calcium hydroxide 4g, boric acid 5g, sodium chloride 20g, mix 20 minutes, then thymol is added in said mixture, mixing 25
Minute, boric acid, sodium chloride and calcium hydroxide are eventually adding, then mixture is water-soluble by proportioning addition 5000ml small molecule deionizations
Solution, filtering, are produced.Sterilized one hour through 100 DEG C of boiling water, filling 50ml/ branch, Different Package type system " safe and simple mouth is made
Chamber cleaning and nursing liquid ".
Embodiment 3
Weigh gluconic acid and determine 3g, promise Buddhist nun's ethanol gel 20g, thymol 5g, papain gel 10g, aloe gel
5g, calcium hydroxide 4.5g, boric acid 8g, sodium chloride 16g, mix 25 minutes, then thymol is added in said mixture, mixing
15 minutes, boric acid, sodium chloride and calcium hydroxide are eventually adding, then mixture is added into 5000ml small molecule deionized waters by proportioning
Dissolving, filtering, is produced.Sterilized one hour through 120 DEG C of boiling water, filling 50ml/ branch, it is " safe and simple that Different Package type system is made
Oral cavity cleaning and nursing liquid ".
Embodiment 4
Weigh gluconic acid and determine 3g, promise Buddhist nun's ethanol gel 25g, thymol 3g, papain gel 15g, aloe gel
4g, calcium hydroxide 3g, boric acid 5g, sodium chloride 10g, mix 20 minutes, then thymol is added in said mixture, mixing 25
Minute, boric acid, sodium chloride and calcium hydroxide are eventually adding, then mixture is water-soluble by proportioning addition 5000ml small molecule deionizations
Solution, filtering, is produced.Sterilized one hour through 100 DEG C ~ 120 DEG C boiling water, filling 50ml/ branch, " the safety letter of Different Package type system is made
Just oral cavity cleaning and nursing liquid ".
Claims (4)
1. a kind of oral cavity cleaning and nursing liquid of CRHD activity, it is characterised in that described conditioning liquid includes following parts by weight thing
Matter：2 ~ 6 parts of gluconic acid chlorhexidine, 3 ~ 25 parts of promise Buddhist nun's ethanol gel, 1 ~ 5 part of thymol, 3 ~ 15 parts of papain gel,
Aloe gel 1:1 ~ 5 part, calcium hydroxide 0.5-5 parts, 1 ~ 6 part of boric acid, 10 ~ 20 parts of sodium chloride, deionized water 4000-6000 parts.
A kind of 2. oral cavity cleaning and nursing liquid of CRHD activity as claimed in claim 1, it is characterised in that described conditioning liquid bag
Following parts by weight material is included：3 parts of gluconic acid chlorhexidine, 6 parts of promise Buddhist nun's ethanol gel, 2 parts of thyme, papain gel
5 parts, 3 parts of aloe gel, 5 parts of calcium hydroxide, 6 parts of boric acid, 15 parts of sodium chloride, 5000 parts of deionized water.
3. a kind of preparation method of the oral cavity cleaning and nursing liquid of CRHD activity, it is characterised in that described preparation method is included such as
Lower step：（1）Raw material is weighed according to proportioning：2 ~ 6 parts of gluconic acid chlorhexidine, 3 ~ 25 parts of promise Buddhist nun's ethanol gel, thymol 1 ~ 5
Part, 3 ~ 15 parts of papain gel, aloe gel 1:1 ~ 5 part, calcium hydroxide 0.5-5 parts, 1 ~ 6 part of boric acid, sodium chloride 10 ~ 20
Part, deionized water 4000-6000 parts；（2）By gluconic acid chlorhexidine, promise Buddhist nun's ethanol gel, papain gel and aloe
Gel is mixed 15 ~ 25 minutes, then thymol is added in said mixture, is mixed 15 ~ 30 minutes；（3）Add boric acid, chlorination
Sodium and calcium hydroxide are added thereto, then mixture is added into appropriate deionized water dissolving, filtering by proportioning；（4）Through 100 DEG C ~
120 DEG C of boiling water sterilize one hour, filling to obtain oral nursing liquid.
4. a kind of preparation method of the oral cavity cleaning and nursing liquid of CRHD activity, it is characterised in that described preparation method is included such as
Lower step：（1）Raw material is weighed according to proportioning：2 ~ 6 parts of gluconic acid chlorhexidine, 3 ~ 8 parts of promise Buddhist nun's ethanol gel, thymol 1 ~ 5
Part, 3 ~ 5 parts of papain gel, aloe gel 1:1 ~ 5 part, calcium hydroxide 0.5-5 parts, 1 ~ 6 part of boric acid, 10 ~ 20 parts of sodium chloride,
Deionized water 4000-6000 parts；（2）By gluconic acid chlorhexidine, promise Buddhist nun's ethanol gel, papain gel and aloe gel
Mixing 25 minutes, then thymol is added in said mixture, mix 20 minutes；（3）Add boric acid, sodium chloride and hydroxide
Calcium is added thereto, then mixture is added to 5000ml deionized water dissolving by proportioning, filtering；（4）Through 100 DEG C ~ 120 DEG C boiling water
Sterilizing one hour, filling 50ml/ props up to obtain oral nursing liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711211191.6A CN107802568A (en) | 2017-11-28 | 2017-11-28 | A kind of oral cavity cleaning and nursing liquid of CRHD activity and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711211191.6A CN107802568A (en) | 2017-11-28 | 2017-11-28 | A kind of oral cavity cleaning and nursing liquid of CRHD activity and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107802568A true CN107802568A (en) | 2018-03-16 |
Family
ID=61590709
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711211191.6A Pending CN107802568A (en) | 2017-11-28 | 2017-11-28 | A kind of oral cavity cleaning and nursing liquid of CRHD activity and preparation method thereof |
Country Status (1)
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| CN (1) | CN107802568A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110236968A (en) * | 2019-07-03 | 2019-09-17 | 深圳市诗碧曼科技有限公司 | A kind of antibacterial mouthwash of anti-ageing healthcare and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080184510A1 (en) * | 2005-06-03 | 2008-08-07 | Mauricio Duarte Da Conceicao | Products for Tongue Cleaning and for Preventing and Treaing Halitosis and Equipment for Tongue Cleaning |
| CN101410086A (en) * | 2006-03-29 | 2009-04-15 | 宝洁公司 | Oral care compositions having improved consumer aesthetics and taste |
| CN106074305A (en) * | 2016-07-29 | 2016-11-09 | 广东俏脸谱文化艺术有限公司 | A kind of Noni fruit toothpaste with oral mucosa protective effect and preparation method thereof |
-
2017
- 2017-11-28 CN CN201711211191.6A patent/CN107802568A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080184510A1 (en) * | 2005-06-03 | 2008-08-07 | Mauricio Duarte Da Conceicao | Products for Tongue Cleaning and for Preventing and Treaing Halitosis and Equipment for Tongue Cleaning |
| CN101410086A (en) * | 2006-03-29 | 2009-04-15 | 宝洁公司 | Oral care compositions having improved consumer aesthetics and taste |
| CN106074305A (en) * | 2016-07-29 | 2016-11-09 | 广东俏脸谱文化艺术有限公司 | A kind of Noni fruit toothpaste with oral mucosa protective effect and preparation method thereof |
Non-Patent Citations (2)
| Title |
|---|
| 余元勋等编: "《中国分子中药学》", 30 June 2017, 安徽科学技术出版社 * |
| 卢勇涛: "复方硼酸含漱液的药理毒理学研究", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110236968A (en) * | 2019-07-03 | 2019-09-17 | 深圳市诗碧曼科技有限公司 | A kind of antibacterial mouthwash of anti-ageing healthcare and preparation method thereof |
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| PB01 | Publication | ||
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Application publication date: 20180316 |