CN107753797A - 一种用于治疗痛风的汤剂药物及其制备方法 - Google Patents

一种用于治疗痛风的汤剂药物及其制备方法 Download PDF

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CN107753797A
CN107753797A CN201711130701.7A CN201711130701A CN107753797A CN 107753797 A CN107753797 A CN 107753797A CN 201711130701 A CN201711130701 A CN 201711130701A CN 107753797 A CN107753797 A CN 107753797A
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罗娟
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Chengdu Feilong Water Treatment Technology Institute
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Abstract

本发明属于中药制剂领域，目的是根据中医治疗痛风的认识机理而提供一种用于治疗痛风的汤剂药物，所述药物的各个组分及其质量份比如下：黄柏3～15g、海金沙6～16g、生地9～16g、茯苓9～16g、黑豆10～36g、五味子2～7g、甘草3～13g、鹿角霜9～16g、陈皮3～15g、泽泻6～12g、薏仁15～56g、鸡内金3～12g、川贝母3～12g、石斛6～16g、没药3～7g；本发明提供的药物是一个很好的中药组方。

Description

一种用于治疗痛风的汤剂药物及其制备方法
技术领域
本发明属于中药制剂领域，具体涉及一种用于治疗痛风的汤剂药物，特别是供痛风患者使用的汤剂药物及其制备方法的领域。
背景技术
祖国医学认为：痛风是由单钠尿酸盐（MSU）沉积所致的晶体相关性关节病，与嘌呤代谢紊乱和（或）尿酸排泄减少所致的高尿酸血症直接相关，特指急性特征性关节炎和慢性痛风石疾病，主要包括急性发作性关节炎、痛风石形成、痛风石性慢性关节炎、尿酸盐肾病和尿酸性尿路结石，重者可出现关节残疾和肾功能不全。痛风常伴腹型肥胖、高脂血症、高血压、2型糖尿病及心血管病等表现。
那么，就如何找到一种可有效治疗痛风的中药组合物，是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗痛风上，人们逐渐意识到了中医治疗痛风的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗痛风的现状，本发明的目的是在于提供一种用于治疗痛风的汤剂药物，以解决痛风患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及质量
份比，可有效治疗上述痛风一证。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种用于治疗痛风的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及质量份比如下所示：
黄柏3～15g、海金沙6～16g、生地9～16g、茯苓9～16g、黑豆10～36g、五味子2～7g、甘草3～13g、鹿角霜9～16g、陈皮3～15g、泽泻6～12g、薏仁15～56g、鸡内金3～12g、川贝母3～12g、石斛6～16g、没药3～7g。
一种用于治疗痛风的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及质量份比如下所示：
黄柏5～13g、海金沙7～14g、生地10～14g、茯苓10～14g、黑豆11～32g、五味子3～6g、甘草5～12g、鹿角霜10～14g、陈皮5～13g、泽泻7～11g、薏仁16～50g、鸡内金5～11g、川贝母5～11g、石斛7～14g、没药4～6g。
一种用于治疗痛风的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及质量份比如下所示：
黄柏12g、海金沙13g、生地13g、茯苓13g、黑豆26g、五味子5g、甘草11g、鹿角霜13g、陈皮12g、泽泻10g、薏仁43g、鸡内金11g、川贝母10g、石斛13g、没药5g。
一种用于治疗痛风的汤剂药物及其制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药拣去杂质和粉尘后，按照质量份比分别粉碎成粗粒状包煎；
B、①将包好的原料中药放入冷开水中浸泡35min，然后再将浸泡好的药物和浸泡药物的澄清液一并放入砂锅内，注入过药65mm的冷开水进行第一次武火煎煮，待煎煮到15min时，转文火熬制35 min，滤取药液；②药渣中再次注入过药60mm的微温开水进行第二次武火煎煮，待煎煮到10min时，转文火熬制30 min，滤取药液；③将两次药液混合浓缩成50%的中药液400ml（毫升）即可。
一种用于治疗痛风的汤剂药物及其制备方法，其特征在于，所述服用方法为：将制备好的中药液以一天服用，每日一剂，早晚分服，给药量200ml（毫升）/次，趁温服。20天为一个疗程，服药3～6个疗程后，经检查：血尿酸降至正常范围，症状消失，已随访一年余，未见复发。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
黄柏，性味：味苦、性寒，具有有清热燥湿、泻火除蒸、解毒疗疮之功效，用于治疗湿热泻痢、黄疸尿赤、带下阴痒、热淋涩痛、脚气痿蹙、骨蒸劳热、盗汗、遗精、疮疡肿毒、湿疹湿疮，盐黄柏滋阴降火，用于阴虚火旺、盗汗骨蒸；
海金沙，性味：味甘、咸、性寒，具有清利湿热、通淋止痛之功效，用于治疗热淋、石淋、血淋、膏淋、尿道涩痛；
生地，性味：甘、寒，具有清热凉血、养阴、生津之功效，用于治疗热病舌绛烦渴、阴虚内热、骨蒸劳热、内热消渴、吐血、衄血、发斑发疹；
茯苓，性味：性平、味甘、淡，具有利水渗湿、健脾宁心之功效，属利水渗湿药下属分类的利水消肿药，用于治疗水肿尿少、痰饮眩悸、脾虚食少、便溏泄泻、心神不安、惊悸失眠；
黑豆，性味：甘、平，具有益精明目、养血祛风、利水、解毒之功效，用于治疗阴虚烦渴、头晕目昏、体虚多汗、肾虚腰痛、水肿尿少、痹痛拘挛、手足麻木、药食中毒；
五味子，性味：酸、甘、温，具有收敛固涩、益气生津、补肾宁心之功效，用于治疗久嗽虚喘、梦遗滑精、遗尿尿频、久泻不止、自汗、盗汗、津伤口渴、短气脉虚、内热消渴、心悸失眠；
甘草，性味：甘、平，具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效，用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒；
鹿角霜，性味：味咸、涩、性温，具有温肾助阳、收敛止血之功效，用于治疗脾肾阳虚、白带过多、遗尿尿频、崩漏下血、疮疡不敛等病症；
陈皮，性味：味辛、苦、性温，具有理气和中，燥湿化痰，利水通便之功效，用于治疗脾胃不和、脘腹胀痛、不思饮食、呕吐哕逆、痰湿阻肺、咳嗽痰多、胸膈满闷、头目眩晕、水肿、小便不利、大便秘结、乳痈疥癣、中鱼蟹毒、酒毒等症
泽泻，性味：味甘、淡、性寒，具有利水渗湿、泄热、化浊降脂之功效，用于治疗小便不利、水肿胀满、泄泻尿少、痰饮眩晕、热淋涩痛、高脂血症；
薏仁，性味：甘、淡、微寒，具有利湿健脾、舒筋除痹、清热排脓之功效，用于治疗水肿、脚气、小便淋沥、湿温病、泄泻带下、风湿痹痛、筋脉拘挛、肺痈、肠痈、扁平疣等症；
鸡内金，性味：甘、平，具有健胃消食、涩精止遗、通淋化石之功效，用于治疗食积不消、呕吐泻痢、小儿疳积、遗尿、遗精、石淋涩痛、胆胀胁痛；
川贝母，性味：性凉，甘平，具有润肺止咳化痰平喘，清热化痰之功效，用于治疗肺热燥咳，干咳少痰，阴虚劳嗽，痰中带血，瘰疬，乳痈，肺痈等症；
石斛，性味：甘、微寒, 具有生津益胃、滋阴清热、润肺益肾、明目强腰之功效，用于治疗热病伤津、口干烦渴、胃阴不足、胃痛干呕、肺燥干咳、虚热不退、阴伤目暗、腰膝软弱；
没药，性味：味辛、苦、性平，具有散瘀定痛、消肿生肌之功效，用于治疗胸痹心痛、胃脘疼痛、痛经经闭、产后瘀阻、癥瘕腹痛、风湿痹痛、跌打损伤、痈肿疮疡。
本发明药物是基于中医治疗痛风的原则，从依据痛风的病理机制及药理作用认为：就痛风一证，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述痛风的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个很好的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种用于治疗痛风的汤剂药物，其特征在于，所述药物的各个组分及质量份比如下所示：
黄柏12g、海金沙13g、生地13g、茯苓13g、黑豆26g、五味子5g、甘草11g、鹿角霜13g、陈皮12g、泽泻10g、薏仁43g、鸡内金11g、川贝母10g、石斛13g、没药5g。
实施例2：
一种用于治疗痛风的汤剂药物，其特征在于，所述药物的各个组分及质量份比如下所示：
黄柏13g、海金沙14g、生地14g、茯苓14g、黑豆32g、五味子6g、甘草12g、鹿角霜14g、陈皮13g、泽泻11g、薏仁50g、鸡内金11g、川贝母11g、石斛14g、没药6g。
实施例3：
一种用于治疗痛风的汤剂药物，其特征在于，所述药物的各个组分及质量份比如下所示：
黄柏15g、海金沙16g、生地16g、茯苓16g、黑豆36g、五味子7g、甘草13g、鹿角霜16g、陈皮15g、泽泻12g、薏仁56g、鸡内金12g、川贝母12g、石斛16g、没药7g。
典型病例：
经临床诊断治疗痛风患者共1360例，年龄为55岁以上的845例，只有515例为55岁以下。1360例患者中血尿酸降至正常范围的有929例，有效的309例，无效的122例。总有效率达91%。

Claims (3)

1.一种用于治疗痛风的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄柏3～15g、海金沙6～16g、生地9～16g、茯苓9～16g、黑豆10～36g、五味子2～7g、甘草3～13g、鹿角霜9～16g、陈皮3～15g、泽泻6～12g、薏仁15～56g、鸡内金3～12g、川贝母3～12g、石斛6～16g、没药3～7g。
2.根据权利要求1所述的用于治疗痛风的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄柏5～13g、海金沙7～14g、生地10～14g、茯苓10～14g、黑豆11～32g、五味子3～6g、甘草5～12g、鹿角霜10～14g、陈皮5～13g、泽泻7～11g、薏仁16～50g、鸡内金5～11g、川贝母5～11g、石斛7～14g、没药4～6g。
3.根据权利要求1至2所述的用于治疗痛风的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
黄柏12g、海金沙13g、生地13g、茯苓13g、黑豆26g、五味子5g、甘草11g、鹿角霜13g、陈皮12g、泽泻10g、薏仁43g、鸡内金11g、川贝母10g、石斛13g、没药5g。
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CN108741024A (zh) * 2018-05-17 2018-11-06 福建省安溪县苷芝宝食品科技有限公司 一种治疗肾结石的营养蜜延浆及其制备工艺

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108741024A (zh) * 2018-05-17 2018-11-06 福建省安溪县苷芝宝食品科技有限公司 一种治疗肾结石的营养蜜延浆及其制备工艺

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