CN107737198A - A kind of Chinese medicine composition for treating chronic cough and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating chronic cough and preparation method thereof Download PDFInfo
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- CN107737198A CN107737198A CN201711328518.8A CN201711328518A CN107737198A CN 107737198 A CN107737198 A CN 107737198A CN 201711328518 A CN201711328518 A CN 201711328518A CN 107737198 A CN107737198 A CN 107737198A
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- chinese medicine
- chronic cough
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Abstract
The present invention relates to a kind of Chinese medicine composition for treating chronic cough and preparation method thereof.The Chinese medicine is by walking borderland, emblic leafflower fruit, asarum caudigerellum, tetramerous jasminorange leaf, Ji Ni, net vein Farfugium kaemferi, lofty or bottomless deep, all Chinese medicine materials such as drawing, swallowwortlike knotweed root are prepared.Present invention also offers the preparation method of this Chinese medicine composition.Chinese medicine composition provided by the invention is mainly used in treating chronic cough.
Description
Technical field
The present invention relates to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition for treating chronic cough and preparation method thereof.
Background technology
Cough is the common sympton of respiratory disease, will be clinically solely or mainly symptom with cough, the time is more than 8
Week, chest X-ray Non Apparent Abnormality person are referred to as unknown cause chronic cough, abbreviation chronic cough.The common class of chronic cough
Type has:Cough variant asthma (cough variant asthma, CVA), postnasal drip symptom or epithelium healing cough are comprehensive
Simulator sickness (upper airway cough syndrome, UACS), Eosinophilic bronchitis (eosinophilic
Bronchitis, EB), gastroesophageal reflux induced cough (gastroesophageal reflux-related chronic
Cough, GERC);This is several to account for the 70%~95% of the Respiratory Medicine chronic cough diagnosed cause of disease.
The traditional Chinese medical science to the understanding origin of chronic cough oneself long,《Miscellaneous diseases origin rhinoceros candle cough, asthma source streams》Medium cloud：" lid lung is not
Cough, spleen do not hinder not chronic cough to wound ".The cause of disease of chronic cough is attributed to lung spleen to be hindered.《Volumes of the 9th, of medical secrets of official chronic cough sides for many years》
21 first 6 clouds：“《Pathogeny》Lung sense is in trembling with fear, and for micro- person then into cough, it is to connect stagnant years, prolonged not thin person that chronic cough, which is coughed,.All the five internal organs
All have cough, endlessly then respectively pass its internal organs, all chronic coughs endlessly, three Jiao by it, its shape cough and abdomen is expired, loss of appetite drink, all cold air gathers for this
In stomach and on lung, make one profuse nasal discharge and spittle and become face edema, the circulation of vital energy in the wrong direction therefore." this is the record earlier defined on chronic cough, simultaneously
The interpretation of the cause, onset and process of an illness for proposing chronic cough is " cold air gathers in stomach and on lung ", and its symptom described is similar to modern Gastroesophageal reflux cough
Cough.
The content of the invention
It is an object of the invention to provide a kind of Chinese medicine composition for treating chronic cough；
It is a further object of the present invention to provide a kind of preparation method for the Chinese medicine composition for treating chronic cough.
The purpose of the present invention is realized by following technical scheme：
The Chinese medicine composition for the treatment of chronic cough of the present invention, is prepared by the Chinese medicine material of following parts by weight：
Walk borderland 10-30 parts, emblic leafflower fruit 8-25 parts, asarum caudigerellum 2-5 parts, tetramerous jasminorange leaf 8-25 part, Ji Ni 2-5 parts, net vein Farfugium kaemferi 20-
40 parts, all lofty or bottomless deep 20-40 parts, drawing 8-25 parts, swallowwortlike knotweed root 10-30 parts.
Preferably, it is to be prepared by the Chinese medicine material of following parts by weight：
Walk borderland 15-25 parts, emblic leafflower fruit 10-20 parts, asarum caudigerellum 3-4 parts, tetramerous jasminorange leaf 10-20 part, Ji Ni 3-4 parts, net vein Farfugium kaemferi
25-35 parts, lofty or bottomless deep 25-35 parts, all draw 10-20 parts, swallowwortlike knotweed root 15-25 parts.
It is the crude drug source of Chinese medicine preparation of the present invention below：
Borderland is walked, is the leaf of Violaceae plant chicken leg violet.It is light, tremble with fear.It is clearing heat and detoxicating, swelling and pain relieving.Cough with lung heat is controlled, bruise swells
Bitterly, sore furuncle poison.
Emblic leafflower fruit, it is the fruit of euphorbia plant phyllanthus emblica.Bitter sweet, tremble with fear；Enter spleen, stomach two passes through.Resolving sputum, promote the production of body fluid, cough-relieving, solution
Poison.Cure cold heating, pharyngalgia of coughing, diphtheria, restlessness and fever with thirst.
Asarum caudigerellum, it is the herb of aristolochiaceae plant short-tail asarum.It is pungent；It is bitter；Temperature.Enter lung, stomach.Expelling wind and clearing away cold；Warm lung
Resolving sputum；Analgesic.Main anemofrigid headache；Phlegm and retained fluid cough and asthma；Stomach cold pain；Stomachache；Dentalgia；Arthralgia pain due to rheumatism；Traumatic injury.
Tetramerous jasminorange leaf, Rutaceae Murraya plant tetramerous jasminorange leaf Murraya tetramera Huang, is used as medicine with Ye Hegen.
Pungent, slight bitter, tepor.Expel pathogenic wind from the body surface, promoting qi circulation and relieving pain, promoting blood circulation to remove blood stasis.For cold, fever, bronchitis, asthma, rheumatic numbness,
Arthralgia and myalgia, bruise blood stasis and swelling pain, pruitus, eczema, venomous snake bite, malaria, stomachache, oedema etc..
Ji Ni, it is Campanulaceae Ji Ni root.It is sweet, tremble with fear.Enter lung, spleen.Heat-clearing, removing toxic substances, resolving sputum.Cough caused by dryness is controlled, has sore throat, disappears
Yearningly, furuncle swelling toxin.
Net vein Farfugium kaemferi, it is the root of feverfew net vein Farfugium kaemferi.Bitter；Slightly warm in nature.Facilitaing lung qi-regulating；Kobadrin.Main flu；
Cough.
Lofty or bottomless depth, it is the lofty or bottomless deep Crepis lignea of composite family hawk's-beard（Vant.）Babc. with the lofty or bottomless depth of the leaf of bamboo
C. phoenis Dunn, it is used as medicine with root.Bitter, micro-sweet, put down.Invigorating the spleen disperse accumulations, clearing heat and detoxicating, lower breast.For infantile malnutrition, milk
Deficiency, bronchitis, pneumonia, hepatitis, leukorrhea, discharging fresh blood stool, arthralgia and myalgia, traumatic injury, boil carbuncle swells.
All draw, be the root of Dipsacaceae plant southwest capsule bud flower.It is sweet；Slight bitter；Slightly warm in nature.Return lung；Spleen；Kidney channel.Warm kidney
QI invigorating；Promoting blood circulation and hemostasis.Main body deadhead dusk；Consumptive disease chronic cough；Insufficiency of the spleen dyspepsia；Lumbago due to the kidney deficiency；Under band；Impotence；It is infertile；Rheumatic heart
Disease；Traumatism and bleeding.
Swallowwortlike knotweed root, it is the root of polygonaceae plant cynanchum auriculatum Royle ex Wight knotweed.Acid；It is pungent；It is cool in nature.Return lung；Stomach.Astringe the lung to stop cough；Promoting the circulation of qi and invigorating stomach；
Dispelling wind and eliminating dampness.Main pulmonary tuberculosis cough；Blood-stained sputum；Pertussis；Epigastric distension and distress pain；Arthralgia pain due to rheumatism.
Another aspect of the present invention there is provided the preparation method of the active component of Chinese medicine composition of the present invention, and this method is
It is prepared using the extraction of the ethanol of water extraction or 40-80% concentration expressed in percentage by volumes.Specific preparation method is as follows：
Scheme one：Take whole medicinal materials, extracting in water 2-3 times after mixing, each amount of water equivalent to 6-12 times of medicinal material gross weight,
Each extraction time is 1-3 hours, merges extract solution, filtration, relative density is 1.15-1.20 when filtrate is concentrated into 70-80 DEG C
Clear cream, produce active component.
Scheme two：Whole medicinal materials are taken, are extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is medicinal material total amount
4-10 times, extraction time is 1-4 hours, merge extract solution, filtering, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, produces active component.
Scheme three：Whole medicinal materials are taken, extracting in water 2-3 times after mixing, 6- of each amount of water equivalent to medicinal material gross weight
12 times, each extraction time is 1-3 hours, merges extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C
1.15-1.20 clear cream, ethanol is added, it is 40-70% to make alcohol content, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80
DEG C when relative density be 1.10-1.25 medicinal extract, produce active component.
The Chinese medicine composition for the treatment of chronic cough of the present invention, can also match somebody with somebody with pharmaceutically acceptable carrier
Close, various oral formulations, such as pill, tablet, capsule, oral liquid, syrup, mixture are made.
The pharmaceutically acceptable carrier of the present invention includes but is not limited to following：
Oral formulations：
Diluent：Starch, Icing Sugar, lactose, dextrin, microcrystalline cellulose, inorganic salts, glycitols etc..
Wetting agent and adhesive：Purified water, ethanol, gelatin, polyethylene glycol, cellulose derivative etc..
Disintegrant：Starch, sodium carboxymethyl starch, cellulose derivative, PVPP etc..
Lubricant：Magnesium stearate, superfine silica gel powder, talcum powder, polyethylene glycol etc..
Cosolvent：Water, ethanol, glycerine, propane diols, liquid paraffin, vegetable oil etc..
Flavouring：Sucrose, monose, aromatic etc..
Preservative：Benzoic acid, sorbic acid, methyl esters, ethyl ester, propyl ester etc..
Method 1：Tablet
Scheme one is taken to add tablet and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention tablet.
Above-mentioned tablet often includes one of diluent, wetting agent, adhesive, disintegrant, lubricant or whole with auxiliary material.
Method 2：Capsule
Scheme one is taken to add capsule and often use auxiliary material, routinely production method is prepared into one of to the gained active component of scheme three
Capsule of the present invention.
Above-mentioned capsule often includes one of diluent, wetting agent, adhesive, disintegrant, lubricant or whole with auxiliary material.
Method 3：Syrup
Scheme one is taken to add syrup and often use auxiliary material, routinely production method is prepared into one of to the gained active component of scheme three
Syrup of the present invention.
Above-mentioned syrup often includes one of flavouring, preservative, cosolvent or whole with auxiliary material.
Method 4：Mixture
Scheme one is taken to add mixture and often use auxiliary material one of to the gained active component of scheme three, routinely production method is prepared into
Invention mixture.
Above-mentioned mixture often includes one of flavouring, preservative or whole with auxiliary material.
Method 5：Oral liquid
Scheme one is taken dissolving after-purification, concentration, to add oral liquid and often use auxiliary material, by normal one of to the gained active component of scheme three
Rule production method is prepared into oral liquid of the present invention.
The applicant reads document at all times extensive, with Traditional Chinese medical theory, suffers to nearly hundred chronic coughs for the treatment of
In the observational study of person, it is believed that the sick position of chronic cough is but close with the visceral dysfunction such as stomach, kidney,liver,spleen, the heart mainly in lung
Cut is closed.In side therefore astringeed the lung to stop cough with the qi-regulating of net vein Farfugium kaemferi facilitaing lung, swallowwortlike knotweed root for monarch.Lofty or bottomless deep invigorating the spleen, emblic leafflower fruit preventing phlegm from forming and stopping coughing,
It is minister all to draw warm kidney.Walk borderland, Ji Ni heat-clearing；Asarum caudigerellum, tetramerous jasminorange leaf wind-dispelling are assistant.Taking a broad view of full side has facilitaing lung cough-relieving, wind-dispelling
Resolving sputum, the effect of conditioning viscera.Full side cooperates, for the cough caused by chronic cough, expectoration, bronchitis, pneumonia, just
Can treatment.
A kind of Chinese medicine composition for treating chronic cough provided by the invention has advantages below：
1st, composite preparation provided by the invention is safe and effective, has a facilitaing lung cough-relieving, dispelling pathogenic wind and eliminating phlegm, the effect of conditioning viscera.Entirely
Side cooperate, for the cough caused by chronic cough, expectoration, bronchitis, pneumonia, can treatment.
2nd, clinical tests prove that, after being treated with the present invention to Chronic Cough Patients, effective percentage shows this hair up to 97.2%
It is bright effectively to treat chronic cough.
3rd, Chinese medicinal composition preparation provided by the invention, scientific formulation is reasonable, and technique is simple, in good taste, and cost is low.
Embodiment
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are to be used to illustrate
The present invention rather than limitation of the present invention.The present invention is belonged to according to the simple modifications that the essence of the present invention is carried out to the present invention
Claimed scope.Unless otherwise indicated, the percentage of the amount of alcohol in the present invention is percentage by volume, and v/v represents solution
Volume ratio.
The capsule of embodiment 1
Weigh away borderland 20g, emblic leafflower fruit 15g, asarum caudigerellum 3g, tetramerous jasminorange leaf 15g, Ji Ni 3g, net vein Farfugium kaemferi 30g, lofty or bottomless deep 30g,
All draw 15g, swallowwortlike knotweed root 20g.Extracted 3 times with 40% alcohol reflux, each ethanol consumption is respectively 10 times of medicinal material total amount, 8 times, 4
Times, extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, filtering, relative density is 1.25 when filtrate concentrates 60 DEG C
Medicinal extract, in medicinal extract add supplementary product starch, ethanol, dextrin, magnesium stearate, capsule is made according to a conventional method.
The granule of embodiment 2
Weigh away borderland 10g, emblic leafflower fruit 8g, asarum caudigerellum 2g, tetramerous jasminorange leaf 8g, Ji Ni 2g, net vein Farfugium kaemferi 20g, lofty or bottomless deep 20g, all
Draw 8g, swallowwortlike knotweed root 10g.Extracted 2 times with alcohol reflux, each concentration of alcohol is respectively 80%, 60%, and each ethanol consumption is respectively
10 times, 8 times of medicinal material total amount, extraction time are respectively 4 hours, 3 hours, merge extract solution, filtering, when filtrate is concentrated into 80 DEG C
Relative density is 1.10 medicinal extract, adds starch, dextrin, and granulation, dry, whole grain produce.
The syrup of embodiment 3
Weigh away borderland 30g, emblic leafflower fruit 25g, asarum caudigerellum 5g, tetramerous jasminorange leaf 25g, Ji Ni 5g, net vein Farfugium kaemferi 40g, lofty or bottomless deep 40g,
All draw 25g, swallowwortlike knotweed root 30g.Extracting in water 2 times, each amount of water are respectively equivalent to 12 times of medicinal material gross weight, 10 times, every time
Extraction time is respectively 3 hours, 2 hours, merges extract solution, filtration, filtrate be concentrated into relative density at 80 DEG C be 1.05 it is clear
Cream, ethanol is added, it is 70% to make alcohol content, stands 12 hours, filtration, and relative density is 1.25 leaching when filtrate is concentrated into 70 DEG C
Cream, addition syrup auxiliary material sucrose, sorbic acid, water stir in medicinal extract, and syrup is made.
The tablet of embodiment 4
Weigh away borderland 15g, emblic leafflower fruit 10g, asarum caudigerellum 3g, tetramerous jasminorange leaf 10g, Ji Ni 3g, net vein Farfugium kaemferi 25g, lofty or bottomless deep 25g,
All draw 10g, swallowwortlike knotweed root 15g.Extracting in water 3 times, amount of water is respectively 12 times of medicinal material gross weight, 8 times, 6 times three times, is carried three times
It is respectively 3 hours, 2 hours, 1 hour to take the time, merges extract solution, filtration, relative density is 1.25 when filtrate is concentrated into 70 DEG C
Clear cream, add supplementary product starch, ethanol, talcum powder, be made tablet.
The granule of embodiment 5
Weigh away borderland 25g, emblic leafflower fruit 20g, asarum caudigerellum 4g, tetramerous jasminorange leaf 20g, Ji Ni 4g, net vein Farfugium kaemferi 35g, lofty or bottomless deep 35g,
All draw 20g, swallowwortlike knotweed root 25g.Extracting in water 2 times, amount of water is respectively 10 times of medicinal material gross weight, 8 times twice, when extracting twice
Between be respectively 2 hours, 1 hour, merge extract solution, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.10 medicinal extract.Add
Starch, dextrin, granulation, dry, whole grain produce.
The tablet of embodiment 6
Weigh away borderland 12g, emblic leafflower fruit 9g, asarum caudigerellum 2g, tetramerous jasminorange leaf 9g, Ji Ni 2g, net vein Farfugium kaemferi 23g, lofty or bottomless deep 23g, all
Draw 9g, swallowwortlike knotweed root 12g.Extracting in water 3 times, three times amount of water be respectively equivalent to 12 times of medicinal material gross weight, 8 times, 6 times, every time
Extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, filtration, relative density is 1.20 when filtrate is concentrated into 70 DEG C
Clear cream, add ethanol, make alcohol content be 40%, stand 24 hours, filtration, filtrate be concentrated into filtrate be concentrated into it is relative at 70 DEG C
Density is 1.10 medicinal extract, adds supplementary product starch, ethanol, talcum powder, and tablet is made.
The mixture of embodiment 7
Weigh away borderland 18g, emblic leafflower fruit 12g, asarum caudigerellum 3g, tetramerous jasminorange leaf 12g, Ji Ni 3g, net vein Farfugium kaemferi 28g, lofty or bottomless deep 28g,
All draw 12g, swallowwortlike knotweed root 18g.Extracting in water 3 times, three times amount of water be respectively equivalent to 12 times of medicinal material gross weight, 8 times, 6 times, often
Secondary extraction time is distinguished 3 hours, 2 hours, 1 hour, merges extract solution, filtration, filtrate concentration ad pond om is medicinal material gross weight
3 times, it is filling, add mixture auxiliary material sucrose, ethyl ester, water, sorbic acid and stir, mixture is made.
The oral liquid of embodiment 8
Weigh away borderland 23g, emblic leafflower fruit 18g, asarum caudigerellum 4g, tetramerous jasminorange leaf 18g, Ji Ni 4g, net vein Farfugium kaemferi 32g, lofty or bottomless deep 32g,
All draw 18g, swallowwortlike knotweed root 23g.Extracting in water 2 times, amount of water is respectively 10 times of medicinal material gross weight, 8 times twice, when extracting twice
Between be respectively 2 hours, 1 hour, merge extract solution, filtration, when filtrate is concentrated into 80 DEG C relative density be 1.10 medicinal extract, soaking
Auxiliary material mannitol, sorbic acid, water are added in cream to stir, and dispense, oral liquid is made.
The pulvis of embodiment 9
Weigh away borderland 28g, emblic leafflower fruit 23g, asarum caudigerellum 4g, tetramerous jasminorange leaf 23g, Ji Ni 4g, net vein Farfugium kaemferi 38g, lofty or bottomless deep 38g,
All draw 23g, swallowwortlike knotweed root 28g.Crush, sieving, produce.
Clinical test is summarized
1st, diagnosis and inclusive criteria
Diagnostic criteria:Western medicine diagnostic criteria can be formulated for 2009 with reference to Chinese Medical Association's respirology《The diagnosis of cough is with controlling
Treat guide》Middle chronic cough diagnostic criteria；
Inclusive criteria:Meet the patient of chronic cough diagnostic criteria, exclude to merge pulmonary tuberculosis, lung bronchogenic carcinoma, chronic obstructive
The Disease such as the chronic respiratory disease such as lung disease history and severe cardiac, liver, kidney, blood；
Except the gestational period, nursing period patient.
2nd, general information
72 patients are observed, it is anti-according to treatment in strict accordance with the chronic cough diagnostic program of the formulations such as Brightling
Answer and further or row lung work(bronchial provocation test, induction of sputum eosinophils count, esophageal barium meal and (or) 24 hours are eaten
Road pH values measure, row bronchoscope, chest CT and nasal sinus CT etc. are checked if necessary.In 72 cases, card type shares 5
Kind, cold drink stops 26, lung, 11, the stagnant throat of phlegm, asthenia of pulmonosplenic qi, phlegm-damp obstructing lung 15, lung yin virtual loss 12, liver-stomach disharmony, stomach Qi
Superinverse 8.
3rd, treatment method
The one week treatment of the embodiment of the present invention 1 is given, the results are shown in Table 1.
4 results
The efficacy result of table 1
| Recovery from illness | It is effective | Effectively | It is invalid | It is efficient（%） | |
| Curative effect | 17 | 38 | 15 | 2 | 97.2 |
Clinical effectiveness is shown：After being treated with the present invention to Chronic Cough Patients, effective percentage shows that the present invention can be effective up to 97.2%
Treat chronic cough.
Model case
Liu XX, female, 8 years old.Coughed before July without obvious inducement, based on dry cough, a small amount of yellow phlegm.Western medicine is given oral 2 months without bright
It is aobvious to alleviate, institute of traditional Chinese medicine's treatment by Chinese herbs 2 months, no alleviation, after be diagnosed as " rhinitis ", without alleviation after treatment, give the embodiment of the present invention 4
Treatment, slightly takes a turn for the better, continual cure is almost recovered after two weeks after three days.
Section X, man, 55 years old, in more than 10 years of chronic cough and asthma, after this is because of flu, cough and asthma aggravated.Chronic facies, lip are slightly purple
Dark purple, emphysematous chest, two lungs hear and a large amount of rhonchus.Give the embodiment of the present invention 6 to treat 6 days, sb.'s illness took a favorable turn.
Although above the present invention is made to retouch in detail with general explanation, embodiment and experiment
State, but on the basis of the present invention, it can be made some modifications or improvements, this is apparent to those skilled in the art
's.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, are belonged to claimed
Scope.
Claims (7)
- A kind of 1. Chinese medicine composition for treating chronic cough, it is characterised in that it be by following parts by weight Chinese medicine material prepare and Into：Walk borderland 10-30 parts, emblic leafflower fruit 8-25 parts, asarum caudigerellum 2-5 parts, tetramerous jasminorange leaf 8-25 part, Ji Ni 2-5 parts, net vein Farfugium kaemferi 20- 40 parts, all lofty or bottomless deep 20-40 parts, drawing 8-25 parts, swallowwortlike knotweed root 10-30 parts.
- 2. the Chinese medicine composition for the treatment of chronic cough as claimed in claim 1, it is characterised in that it is by including following weight What the Chinese medicine material of part was prepared：Walk borderland 15-25 parts, emblic leafflower fruit 10-20 parts, asarum caudigerellum 3-4 parts, tetramerous jasminorange leaf 10-20 part, Ji Ni 3-4 parts, net vein Farfugium kaemferi 25-35 parts, lofty or bottomless deep 25-35 parts, all draw 10-20 parts, swallowwortlike knotweed root 15-25 parts.
- 3. the Chinese medicine composition for the treatment of chronic cough as claimed in claim 1 or 2, it is characterised in that its active component is to adopt It is prepared with the extraction of the ethanol of water extraction or 40-80% concentration expressed in percentage by volumes.
- 4. the Chinese medicine composition for the treatment of chronic cough as claimed in claim 3, it is characterised in that its active component is to pass through What following methods were prepared：Whole medicinal materials are taken, extracting in water 2-3 times after mixing, each amount of water is equivalent to medicinal material gross weight 6-12 times, each extraction time is 1-3 hours, merge extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream, produces active component.
- 5. the Chinese medicine composition for the treatment of chronic cough as claimed in claim 3, it is characterised in that its active component is to pass through What following methods were prepared：Whole medicinal materials are taken, are extracted 2-3 times with 40-80% alcohol refluxs after mixing, each ethanol consumption is 4-10 times of medicinal material total amount, extraction time are 1-4 hours, merge extract solution, filtering, filtrate is concentrated into relatively close at 70-80 DEG C The clear cream for 1.15-1.20 is spent, produces active component.
- 6. the Chinese medicine composition for the treatment of chronic cough as claimed in claim 3, it is characterised in that its active component is to pass through What following methods were prepared：Whole medicinal materials are taken, extracting in water 2-3 times after mixing, each amount of water is equivalent to medicinal material gross weight 6-12 times, each extraction time is 1-3 hours, merge extract solution, filtration, relative density is when filtrate is concentrated into 70-80 DEG C 1.15-1.20 clear cream, ethanol is added, it is 40-70% to make alcohol content, stands 12-24 hours, and filtration, filtrate is concentrated into 70-80 DEG C when relative density be 1.10-1.25 medicinal extract, produce active component.
- 7. a kind of preparation for treating chronic cough, Chinese medicine composition and doctor as the treatment chronic cough described in claim 1-6 Pharmaceutically acceptable carrier, which prepares, to be formed.
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| CN102793841A (en) * | 2012-08-20 | 2012-11-28 | 孔庆玉 | Traditional Chinese medicine composition for treating pediatric acute bronchitis |
| US20140023731A1 (en) * | 2002-09-12 | 2014-01-23 | Wilfred-Ramix, Inc. | Composition for treating aids and associated conditions |
| CN105327130A (en) * | 2015-11-14 | 2016-02-17 | 郑梅 | Traditional Chinese medicine composition for treating upper airway cough syndromes and nursing method |
| CN107184934A (en) * | 2017-05-26 | 2017-09-22 | 毛里夏里甫·哈帕 | It is a kind of to treat medicine of respiratory disease and preparation method thereof and application method |
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2017
- 2017-12-13 CN CN201711328518.8A patent/CN107737198A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140023731A1 (en) * | 2002-09-12 | 2014-01-23 | Wilfred-Ramix, Inc. | Composition for treating aids and associated conditions |
| CN102793841A (en) * | 2012-08-20 | 2012-11-28 | 孔庆玉 | Traditional Chinese medicine composition for treating pediatric acute bronchitis |
| CN105327130A (en) * | 2015-11-14 | 2016-02-17 | 郑梅 | Traditional Chinese medicine composition for treating upper airway cough syndromes and nursing method |
| CN107184934A (en) * | 2017-05-26 | 2017-09-22 | 毛里夏里甫·哈帕 | It is a kind of to treat medicine of respiratory disease and preparation method thereof and application method |
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Application publication date: 20180227 |