CN109498787A - A kind of Chinese medicine composition for oral administration and sticking combination for treating laryngeal cough - Google Patents

A kind of Chinese medicine composition for oral administration and sticking combination for treating laryngeal cough Download PDF

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Publication number
CN109498787A
CN109498787A CN201811579433.1A CN201811579433A CN109498787A CN 109498787 A CN109498787 A CN 109498787A CN 201811579433 A CN201811579433 A CN 201811579433A CN 109498787 A CN109498787 A CN 109498787A
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chinese medicine
parts
oral administration
traditional chinese
cough
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张红参
赵玉峰
窦锡彬
黄锁义
关皓邺
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YOUJIANG NATIONAL MEDICAL COLLEGE
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YOUJIANG NATIONAL MEDICAL COLLEGE
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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Abstract

The present invention discloses a kind of Chinese medicine composition for oral administration and sticking combination for treating laryngeal cough, wherein, the present invention includes traditional Chinese medicine for oral administration and sticks Chinese medicine, and traditional Chinese medicine for oral administration is made of Chinese olive, campanulaceae, Radix Glycyrrhizae, honeysuckle, four number kamuning, dried orange peel, rhizoma zingiberis, Schisandra chinensis drug;Chinese medicine is sticked to be made of blackberry lily, Chinese ephedra, asarum, semen brassicae, perillaseed, indigo naturalis, four number kamuning;The present invention is according to theory of traditional Chinese medical science and modern medical theory, by using oral traditional Chinese medicine composition and the mode that drug composition combines is sticked with the cure rate of the raising laryngeal cough reached, and achieve the purpose that treatment laryngeal cough without side-effects, oral traditional Chinese medicine composition of the invention has the effect of wind-dispelling dissipates heresy, relieving sore-throat eliminating the phlegm, ventilating the lung and relieving cough, and sticking drug composition has the effect of energy clearing benefit lung, cough-relieving apophlegmatic;Moreover formula of the invention is reasonable, and medicine source is wide, at low cost, significant in efficacy.

Description

A kind of Chinese medicine composition for oral administration and sticking combination for treating laryngeal cough
[technical field]
The invention belongs to field of pharmaceutical technology, in particular to a kind of Chinese medicine for oral administration and sticking combination for treating laryngeal cough Composition.
[background technique]
Laryngeal cough, its main feature is that often first because in throat surprise itch unbearably, cough is in paroxysmal, spastic, and cough is not then It is, pharyngeal scorching hot with dry throat once cough, then last for several minutes to dozens of minutes or even a few hours, tears all go out when cough, Phlegm without or phlegm lack sticky difficulty and go out, the course of disease several months is not cured even year in year out.
At present clinically to the treatment of the disease, doctor trained in Western medicine antibiotic ineffective, Chinese medicine uses merely pectoral, most of to treat Effect is not significant.
[summary of the invention]
The main object of the present invention is to provide a kind of Chinese medicine composition for oral administration and sticking combination for treating laryngeal cough, It is intended to improve the cure rate of laryngeal cough.
To achieve the above object, the Chinese medicine composition for oral administration and sticking combination for the treatment of laryngeal cough proposed by the present invention It include: traditional Chinese medicine for oral administration and to stick Chinese medicine, traditional Chinese medicine for oral administration is made of following raw materials according drug: Chinese olive, campanulaceae, Radix Glycyrrhizae, honeysuckle, four numbers Kamuning, dried orange peel, rhizoma zingiberis, Schisandra chinensis;
Chinese medicine is sticked to be made of following raw materials according drug: blackberry lily, Chinese ephedra, asarum, semen brassicae, perillaseed, indigo naturalis, in four nine periods It is fragrant.
Preferably, the traditional Chinese medicine for oral administration is by following parts by weight quantity medicine group at Chinese olive 10-20, campanulaceae 10-20, Radix Glycyrrhizae 10-15, honeysuckle 10-20g, four number kamuning 10-15, dried orange peel 10-15, rhizoma zingiberis 10-20, Schisandra chinensis 10-30;
It is described to stick Chinese medicine by following parts by weight quantity medicine group into blackberry lily 10-30, Chinese ephedra 10-30, asarum 10-30, it is white Mustard seed 10-30, perillaseed 10-30, indigo naturalis 10-15, four number kamuning 10-30.
Preferably, the traditional Chinese medicine for oral administration the preparation method comprises the following steps:
1) Chinese olive, campanulaceae, Radix Glycyrrhizae, honeysuckle, four number kamuning, dried orange peel, rhizoma zingiberis, Schisandra chinensis are washed with clear water respectively Only, be placed in shady place dry it is spare;
2) raw material in step 1) is put into container, clear water is added to impregnate 40min-50min;
3) Chinese medicine after impregnating in step 2), which is put, is sequentially placed into frying pan, and a certain amount of clear water is added, is decocted using intense fire 20min-30min, then turn mild fire decoction 20min-30min after, the screen to filtrate obtains filtrate I and Chinese medicine filter residue, and the filtrate I is quiet Set to room temperature it is spare after, using centrifuge carry out centrifugal treating, obtain concentration be 20%-35% concentrate I;
4) the Chinese medicine filter residue in step 3) is placed again into frying pan and is added quantitative clear water, after being heated to boiling Turn mild fire decoction 20min-30min, the screen to filtrate obtains filtrate II, filtrate II is carried out centrifugal treating using centrifuge, concentration is made For the concentrate II of 35%-55%;
5) step 3) is mixed with concentrate I obtained in step 4) with concentrate II and blender is used to stir 10min- 20min obtains traditional Chinese medicine for oral administration;
It is described stick Chinese medicine the preparation method comprises the following steps:
1) blackberry lily, Chinese ephedra, asarum, semen brassicae, perillaseed, indigo naturalis, four number kamuning are cleaned with clear water respectively, is placed in Shady place is dried spare;
2) white wine of 45%-65% is uniformly sprayed in the Chinese medicine surface of step 1), and puts and steams 30min- into steamer It is In Shade to air-dry after 50min;
3) Chinese medicine after steaming in step 2) is placed in iron pan and stands room temperature after stir-fry to 20min-30min;
4) Chinese medicine in step 3) Jing Guo frying is crushed to the herb powder mixture of 100-120 mesh using pulverizer;
5) honey and transdermal agent azone is added in herb powder mixture described in step 4), and is sufficiently stirred to contain Water is the Traditional Chinese drug mixture of 30%-45%, and the Traditional Chinese drug mixture is put into die for molding, must stick Chinese medicine.
Preferably, the ratio of clear water and Chinese medicine is respectively in step 3) and step 4) in the preparation method of the traditional Chinese medicine for oral administration 1:15 and 1:10.
Preferably, mold is circle in step 5) in the preparation method for sticking Chinese medicine, and diameter is 2cm-3cm, With a thickness of 1.5mm-2.0mm.
The present invention by using oral traditional Chinese medicine composition and sticks drug composition according to theory of traditional Chinese medical science and modern medical theory The mode combined reaches treatment laryngeal cough without side-effects with the cure rate of the raising laryngeal cough reached Purpose, oral traditional Chinese medicine composition of the invention have the effect of wind-dispelling dissipates heresy, relieving sore-throat eliminating the phlegm, ventilating the lung and relieving cough, stick drug composition There is the effect of energy clearing benefit lung, cough-relieving apophlegmatic;Moreover formula of the invention is reasonable, and medicine source is wide, at low cost, and curative effect is aobvious It writes.
[specific embodiment]
The following examples can help those skilled in the art that the present invention is more completely understood, but cannot be with any Mode limits the present invention.
Embodiment 1
During a kind of Chinese medicine composition treated for oral administration of laryngeal cough and stick combination includes: traditional Chinese medicine for oral administration and sticks Medicine.
The traditional Chinese medicine for oral administration the preparation method comprises the following steps:
1) it takes 15 parts of Chinese olive, 15 parts of campanulaceae, 10 parts of Radix Glycyrrhizae, 15 parts of honeysuckle, four 10 parts of kamuning of number, 10 parts of dried orange peel, do 15 parts of ginger, 20 parts of Schisandra chinensis simultaneously clean the above Chinese medicine with clear water respectively, be placed in shady place dry it is spare;
2) raw material in step 1) is put into container, clear water is added to impregnate 40min-50min;
3) Chinese medicine after impregnating in step 2), which is put, is sequentially placed into frying pan, and the clear water of 15 times of parts is added, is decocted using intense fire 20min-30min, then turn mild fire decoction 20min-30min after, the screen to filtrate obtains filtrate I and Chinese medicine filter residue, and the filtrate I is quiet Set to room temperature it is spare after, using centrifuge carry out centrifugal treating, obtain concentration be 20%-35% concentrate I;
4) the Chinese medicine filter residue in step 3) is placed again into the clear water that 10 times of parts in frying pan and are added, is heated to boiling After turn mild fire decoction 20min-30min, the screen to filtrate obtains filtrate II, and filtrate II is carried out centrifugal treating using centrifuge and is made dense Degree is the concentrate II of 35%-55%;
5) step 3) is mixed with concentrate I obtained in step 4) with concentrate II and blender is used to stir 10min- 20min obtains traditional Chinese medicine for oral administration;
This stick Chinese medicine the preparation method comprises the following steps:
1) take 30 parts of blackberry lily, 30 parts of Chinese ephedra, 30 parts of asarum, 30 parts of semen brassicae, 30 parts of perillaseed, 15 parts of indigo naturalis, in four nine periods Fragrant 30 parts are cleaned with clear water respectively, it is In Shade dry it is spare;
2) white wine of 45%-65% is uniformly sprayed in the Chinese medicine surface of step 1), and puts and steams 30min- into steamer It is In Shade to air-dry after 50min;
3) Chinese medicine after steaming in step 2) is placed in iron pan and stands room temperature after stir-fry to 20min-30min;
4) Chinese medicine in step 3) Jing Guo frying is crushed to the herb powder mixture of 100-120 mesh using pulverizer;
5) honey and transdermal agent azone is added in herb powder mixture described in step 4), and is sufficiently stirred to contain Water is the Traditional Chinese drug mixture of 30%-45%, and the Traditional Chinese drug mixture is put into die for molding, which is circle, and Diameter is 2cm-3cm, with a thickness of 1.5mm-2.0mm, must stick Chinese medicine.
Traditional Chinese medicine for oral administration of the present invention and the function of sticking Chinese medicine each component are respectively as follows:
Chinese olive: it is mild-natured, it is sweet in flavor, puckery, sour, enter lung, stomach meridian, the function with removing heat from the lung and relieving sorethroat cough-relieving, removing toxic substances of promoting the production of body fluid cures mainly throat Swelling and pain, polydipsia, cough are spitted blood, bacillary dysentery, epilepsy, solution river intestines poison and wine poison." book on Chinese herbal medicine new again " cloud: " calming the liver appetizing, moistening lung enriching yin, Cough is controlled in clear phlegm qi-regulating ".And Chinese olive has the main components such as gallic acid, scopolactone and escoparone, can be with heat-clearing Relieving sore-throat has good therapeutic effect to diseases such as acute and chronic sphagitis, chronic bronchitis and bronchiectasis.
Campanulaceae: it is mild-natured, it is bitter, pungent, enter lung channel, has effects that promoting the dispersing function of the lung, relieving sore-throat, method phlegm, apocenosis, cure mainly coughing with a lot of sputum, chest It is bored unsmooth, pharyngalgia hoarse voice, lung carbuncle pyemesis." Thunder God process drug property cerse solution " is said: " its with having four: only pharyngalgia, and except having a stuffy nose;Sharp diaphragm Gas still controls pulmonary abscess;One collects for all boats of all medicines;One is the tying-in of lung." collected statements on the herbal foundation ": the main sharp lung qi of the withered stalk of " leads to pharynx diaphragm, Regulating the flow of vital energy and removing obstruction toit opens the medicine of strongly fragrant row phlegm.All cough phlegm asthmas, non-this do not remove, and have the function of pleasant slit phlegm with it.Quote from [China is originally Grass]." " explaining abstruseness of the canon of materia medica ": " withered stalk is used, precisely because on enter lung channel, gas is dirty based on lung, therefore all gas can be made to decline, and secular mud is upper The agent of liter is unable to downlink, loses it and uses.Quote from [China's book on Chinese herbal medicine]." licorice, it is cold nature, sweet in flavor, flat, have it is clearing heat and detoxicating, The effect of relieving sore-throat of relieving inflammation or internal heat, cure mainly abscess of throat.Sweet taste and moisten, have the function of moistening lung to arrest cough.It is recorded in " drugization justice ": "
Radix Glycyrrhizae: specially enter the spleen channel.Taking property gas is slow, slow to go urgency, delays its heat with it with the medicine of a warm nature, tremble with fear it is medicinal delay that it is cold, make to mend It is unlikely rapid, and rush down and be unlikely to fast, have and reconciles the justice of mutually association, therefore the old " of Cheng Yue " state.It gives birth to the purging intense heat with cool, and main scattered table is evil, disappears silly Swollen, relieving sore-throat pain solves hundred poisoning of druies, removes stomach accumulated heat, goes urinary catheter pain, this sweet and cool-natured is except heat, power.Toast bowl spares with temperature, main spleen deficiency cunning are rushed down, Stomach void is thirsty, and fever and chills cough, shortness of breath is sleepy, and forced labour is deficient, this sweet temperature helps the function of spleen.But rich and too sweet tea, it is unsuitable in tonic It is multi-purpose, it probably loves every not thinking food.This disease of " is occurred with " larynx source " name, diseased region in throat, therefore withered stalk is used with Radix Glycyrrhizae 5, i.e., It is the famous withered stalk soup of treatise on Febrile Diseases.The two energy relieving sore-throat method phlegm, ventilating the lung and relieving cough, and it is withered obstruct into lung channel, as guiding action medicine energy Priming uplink guides drugs to illness station.
Honeysuckle: cold in nature, return lung sweet in flavor, effect are clearing heat and detoxicating, dispelling wind and heat from the body.This product is sweet cold, and fragrance evacuation is apt to dissipate Lung channel heat evil, it is diathermanous reach table, cure mainly affection of exogenous wind-heat or warm disease from the beginning of disease.
Four number kamuning: be also known as murraya paniculataJack, spice all over the mountain, cross bee saage, tetramerous jasminorange leaf etc., it is Rutaceae Murraya plant, is A kind of deciduous tree, have expel pathogenic wind from the body surface, promoting qi circulation and relieving pain, promoting blood circulation scattered silt, it is anti-inflammatory, analgesia, it is antipyretic the effect of, for catch a cold hair Heat, bronchitis, asthma, rheumatic numbness, arthralgia and myalgia, bruise blood stasis and swelling pain, pruitus, eczema, venomous snake bite, malaria, Stomachache, oedema etc..And containing compounds such as psoralens in four number kamuning, psoralen (psoralen, PSO) has wide General biological activity and pharmacological action has diastole effect etc. to bronchial smooth muscle.
Dried orange peel: it is warm-natured, there is the function of promoting qi circulation and relieving pain, invigorating spleen, it is dry because of its bitter temperature, therefore the stagnation of the circulation of vital energy in cold-dampness resistance is most Preferably;Xin Xiang and go, regulating functional activities of vital QI is adjusted burnt in smooth and to be allowed to lifting orderly;Dried orange peel can eliminating dampnessization it is thin, moreover it is possible to Wen Huahan is praised, and Pungent row hardship is let out and energy ventilating the lung and relieving cough, for the key medicine for controlling phlegm.
Rhizoma zingiberis: pungent-warm, warming spleen and stomach for dispelling cold, warming lung and resolving fluid;Schisandra chinensis acid temperature, astringency inducing, nourishing generate fluid.In its cured the disease card With sick position in lung, it is distinguishing feature that symptom, which has cough,.Rhizoma zingiberis is pungent to be dissipated, and Schisandra chinensis acid is received, and the two one dissipates one and receives, and one, which opens one, holds back, and is just accord with Lung department opens the principles of action that are entire, exhaling the old and inhale the new.Second rhizoma zingiberis, Schisandra chinensis share, and have the effect of warming spleen and stomach for dispelling cold, warming lung and resolving fluid, and middle benefit gas can Exhausted the source of producing phlegm is the incoming road for controlling cough;Warm lung can swing the device of storage phlegm, be the outlet of clear phlegm, and air flue is smooth clearly, and cough is from only.
Blackberry lily: cold in nature, bitter, it is distributed in lung channel, it is this product purging with bitter and cold drugs, clearing heat and detoxicating, it is main enter lung channel, have clearing lung-heat purging intense heat, relieving sore-throat The function of detumescence, to control abscess of throat common medicine.Its especially kind clearing lung-heat fire, sending down abnormally ascending dissolving phlegm, with antiasthmatic-antitussive.
The effect of Chinese ephedra: warm-natured, acrid flavour, slight bitter, return lung, bladder meridian have inducing sweat and dispelling exogenous evils, freeing lung and relieving asthma, inducing diuresis for removing edema.
Asarum: warm-natured, acrid flavour, return lung, kidney channel have wind-expelling pain-stopping, expelling cold and relieving exterior syndrome, and warming lung and resolving fluid declares clearing the nasal passage.Asarum Aroma is dense, and property is apt to walk to alter, and treatment coughs its main function as the cold drink in energy temperatureization lung, solves trembling with fear in lung and coagulates.
Semen brassicae: warm-natured, acrid flavour, it is nontoxic, enter lung, the warp of stomach two, pungent to enter lung, temperature can dissipate table, therefore have warm lung slit phlegm benefit gas, Mammary gland dissipating bind is removed obstruction in channels to relieve pain.For phlegm asthma cough of trembling with fear, distending pain in the chest and hypochondrium, the stagnant channels and collaterals of phlegm, joint numbness, pain, phlegm-damp oozing in the body, negative subcutaneous ulcer is swollen Poison.Semen brassicae contains potassium myronate, meets water through the effect of myrosase and generates volatile oil, main component is allyl isothiocyanate, is had Pungent acid and stimulation are three nine-day periods after the winter solstice patch and three submissive main ingredients.Perillaseed, warm-natured, acrid flavour, return lung, the spleen channel have sending down abnormally ascending Dissolving phlegm is relievingd asthma, ease constipation and other effects, is used for phlegm stops up the circulation of vital energy in the wrong direction, cough and asthma, dry constipation of intestines.
Indigo naturalis: cold in nature, taste is salty to have clearing heat-fire, and the function of removing pattogenic heat from the blood and toxic material from the body, curing mainly pulmonary cough,cough with the lung involved has hot phlegm person.
Embodiment 2
The traditional Chinese medicine for oral administration the preparation method comprises the following steps:
1) it takes 10 parts of Chinese olive, 10 parts of campanulaceae, 10 parts of Radix Glycyrrhizae, 10 parts of honeysuckle, four 10 parts of kamuning of number, 10 parts of dried orange peel, do 10 parts of ginger, 10 parts of Schisandra chinensis simultaneously clean the above Chinese medicine with clear water respectively, be placed in shady place dry it is spare;
2) raw material in step 1) is put into container, clear water is added to impregnate 40min-50min;
3) Chinese medicine after impregnating in step 2), which is put, is sequentially placed into frying pan, and the clear water of 15 times of parts is added, is decocted using intense fire 20min-30min, then turn mild fire decoction 20min-30min after, the screen to filtrate obtains filtrate I and Chinese medicine filter residue, and the filtrate I is quiet Set to room temperature it is spare after, using centrifuge carry out centrifugal treating, obtain concentration be 20%-35% concentrate I;
4) the Chinese medicine filter residue in step 3) is placed again into the clear water that 10 times of parts in frying pan and are added, is heated to boiling After turn mild fire decoction 20min-30min, the screen to filtrate obtains filtrate II, and filtrate II is carried out centrifugal treating using centrifuge and is made dense Degree is the concentrate II of 35%-55%;
5) step 3) is mixed with concentrate I obtained in step 4) with concentrate II and blender is used to stir 10min- 20min obtains traditional Chinese medicine for oral administration;
This stick Chinese medicine the preparation method comprises the following steps:
1) take 30 parts of blackberry lily, 30 parts of Chinese ephedra, 30 parts of asarum, 30 parts of semen brassicae, 30 parts of perillaseed, 15 parts of indigo naturalis, in four nine periods Fragrant 30 parts are cleaned with clear water respectively, it is In Shade dry it is spare;
2) white wine of 45%-65% is uniformly sprayed in the Chinese medicine surface of step 1), and puts and steams 30min- into steamer It is In Shade to air-dry after 50min;
3) Chinese medicine after steaming in step 2) is placed in iron pan and stands room temperature after stir-fry to 20min-30min;
4) Chinese medicine in step 3) Jing Guo frying is crushed to the herb powder mixture of 100-120 mesh using pulverizer;
5) honey and transdermal agent azone is added in herb powder mixture described in step 4), and is sufficiently stirred to contain Water is the Traditional Chinese drug mixture of 30%-45%, and the Traditional Chinese drug mixture is put into die for molding, which is circle, and Diameter is 2cm-3cm, with a thickness of 1.5mm-2.0mm, must stick Chinese medicine.
Embodiment 3
The traditional Chinese medicine for oral administration the preparation method comprises the following steps:
1) it takes 20 parts of Chinese olive, 15 parts of campanulaceae, 12 parts of Radix Glycyrrhizae, 10 parts of honeysuckle, four 10 parts of kamuning of number, 10 parts of dried orange peel, do 20 parts of ginger, 20 parts of Schisandra chinensis simultaneously clean the above Chinese medicine with clear water respectively, be placed in shady place dry it is spare;
2) raw material in step 1) is put into container, clear water is added to impregnate 40min-50min;
3) Chinese medicine after impregnating in step 2), which is put, is sequentially placed into frying pan, and the clear water of 15 times of parts is added, is decocted using intense fire 20min-30min, then turn mild fire decoction 20min-30min after, the screen to filtrate obtains filtrate I and Chinese medicine filter residue, and the filtrate I is quiet Set to room temperature it is spare after, using centrifuge carry out centrifugal treating, obtain concentration be 20%-35% concentrate I;
4) the Chinese medicine filter residue in step 3) is placed again into the clear water that 10 times of parts in frying pan and are added, is heated to boiling After turn mild fire decoction 20min-30min, the screen to filtrate obtains filtrate II, and filtrate II is carried out centrifugal treating using centrifuge and is made dense Degree is the concentrate II of 35%-55%;
5) step 3) is mixed with concentrate I obtained in step 4) with concentrate II and blender is used to stir 10min- 20min obtains traditional Chinese medicine for oral administration;
This stick Chinese medicine the preparation method comprises the following steps:
1) take 30 parts of blackberry lily, 30 parts of Chinese ephedra, 30 parts of asarum, 30 parts of semen brassicae, 30 parts of perillaseed, 20 parts of indigo naturalis, in four nine periods Fragrant 20 parts are cleaned with clear water respectively, it is In Shade dry it is spare;
2) white wine of 45%-65% is uniformly sprayed in the Chinese medicine surface of step 1), and puts and steams 30min- into steamer It is In Shade to air-dry after 50min;
3) Chinese medicine after steaming in step 2) is placed in iron pan and stands room temperature after stir-fry to 20min-30min;
4) Chinese medicine in step 3) Jing Guo frying is crushed to the herb powder mixture of 100-120 mesh using pulverizer;
5) honey and transdermal agent azone is added in herb powder mixture described in step 4), and is sufficiently stirred to contain Water is the Traditional Chinese drug mixture of 30%-45%, and the Traditional Chinese drug mixture is put into die for molding, which is circle, and Diameter is 2cm-3cm, with a thickness of 1.5mm-2.0mm, must stick Chinese medicine.
Embodiment 4
The traditional Chinese medicine for oral administration the preparation method comprises the following steps:
1) it takes 15 parts of Chinese olive, 15 parts of campanulaceae, 12 parts of Radix Glycyrrhizae, 10 parts of honeysuckle, four 10 parts of kamuning of number, 10 parts of dried orange peel, do 20 parts of ginger, 20 parts of Schisandra chinensis simultaneously clean the above Chinese medicine with clear water respectively, be placed in shady place dry it is spare;
2) raw material in step 1) is put into container, clear water is added to impregnate 40min-50min;
3) Chinese medicine after impregnating in step 2), which is put, is sequentially placed into frying pan, and the clear water of 15 times of parts is added, is decocted using intense fire 20min-30min, then turn mild fire decoction 20min-30min after, the screen to filtrate obtains filtrate I and Chinese medicine filter residue, and the filtrate I is quiet Set to room temperature it is spare after, using centrifuge carry out centrifugal treating, obtain concentration be 20%-35% concentrate I;
4) the Chinese medicine filter residue in step 3) is placed again into the clear water that 10 times of parts in frying pan and are added, is heated to boiling After turn mild fire decoction 20min-30min, the screen to filtrate obtains filtrate II, and filtrate II is carried out centrifugal treating using centrifuge and is made dense Degree is the concentrate II of 35%-55%;
5) step 3) is mixed with concentrate I obtained in step 4) with concentrate II and blender is used to stir 10min- 20min obtains traditional Chinese medicine for oral administration;
This stick Chinese medicine the preparation method comprises the following steps:
1) take 30 parts of blackberry lily, 30 parts of Chinese ephedra, 30 parts of asarum, 30 parts of semen brassicae, 30 parts of perillaseed, 20 parts of indigo naturalis, in four nine periods Fragrant 20 parts are cleaned with clear water respectively, it is In Shade dry it is spare;
2) white wine of 45%-65% is uniformly sprayed in the Chinese medicine surface of step 1), and puts and steams 30min- into steamer It is In Shade to air-dry after 50min;
3) Chinese medicine after steaming in step 2) is placed in iron pan and stands room temperature after stir-fry to 20min-30min;
4) Chinese medicine in step 3) Jing Guo frying is crushed to the herb powder mixture of 100-120 mesh using pulverizer;
5) honey and transdermal agent azone is added in herb powder mixture described in step 4), and is sufficiently stirred to contain Water is the Traditional Chinese drug mixture of 30%-45%, and the Traditional Chinese drug mixture is put into die for molding, which is circle, and Diameter is 2cm-3cm, with a thickness of 1.5mm-2.0mm, must stick Chinese medicine.
Embodiment 5
The traditional Chinese medicine for oral administration the preparation method comprises the following steps:
1) it takes 20 parts of Chinese olive, 15 parts of campanulaceae, 15 parts of Radix Glycyrrhizae, 20 parts of honeysuckle, four 10 parts of kamuning of number, 10 parts of dried orange peel, do 10 parts of ginger, 25 parts of Schisandra chinensis simultaneously clean the above Chinese medicine with clear water respectively, be placed in shady place dry it is spare;
2) raw material in step 1) is put into container, clear water is added to impregnate 40min-50min;
3) Chinese medicine after impregnating in step 2), which is put, is sequentially placed into frying pan, and the clear water of 15 times of parts is added, is decocted using intense fire 20min-30min, then turn mild fire decoction 20min-30min after, the screen to filtrate obtains filtrate I and Chinese medicine filter residue, and the filtrate I is quiet Set to room temperature it is spare after, using centrifuge carry out centrifugal treating, obtain concentration be 20%-35% concentrate I;
4) the Chinese medicine filter residue in step 3) is placed again into the clear water that 10 times of parts in frying pan and are added, is heated to boiling After turn mild fire decoction 20min-30min, the screen to filtrate obtains filtrate II, and filtrate II is carried out centrifugal treating using centrifuge and is made dense Degree is the concentrate II of 35%-55%;
5) step 3) is mixed with concentrate I obtained in step 4) with concentrate II and blender is used to stir 10min- 20min obtains traditional Chinese medicine for oral administration;
This stick Chinese medicine the preparation method comprises the following steps:
1) take 30 parts of blackberry lily, 30 parts of Chinese ephedra, 30 parts of asarum, 25 parts of semen brassicae, 30 parts of perillaseed, 15 parts of indigo naturalis, in four nine periods Fragrant 20 parts are cleaned with clear water respectively, it is In Shade dry it is spare;
2) white wine of 45%-65% is uniformly sprayed in the Chinese medicine surface of step 1), and puts and steams 30min- into steamer It is In Shade to air-dry after 50min;
3) Chinese medicine after steaming in step 2) is placed in iron pan and stands room temperature after stir-fry to 20min-30min;
4) Chinese medicine in step 3) Jing Guo frying is crushed to the herb powder mixture of 100-120 mesh using pulverizer;
5) honey and transdermal agent azone is added in herb powder mixture described in step 4), and is sufficiently stirred to contain Water is the Traditional Chinese drug mixture of 30%-45%, and the Traditional Chinese drug mixture is put into die for molding, which is circle, and Diameter is 2cm-3cm, with a thickness of 1.5mm-2.0mm, must stick Chinese medicine.
Experimental example:
In order to prove effectiveness of the invention, inventor by traditional Chinese medicine for oral administration of the invention and sticked application in TCM in 2018 In clinic, with diagnostic criteria are as follows: 1) clinical manifestation is with dry cough without phlegm or few phlegm, and pharynx suddenly and repeatedly is itched cough, or such as foreign matter Obstruction, notably cough and feel sick for main feature, pharyngeal mucous membrane checks without exception or visible pharyngeal or throat's mucous membrane mild swelling, It is micro- red;2) auscultation of lung is without exception, the inspections such as rabat, blood routine, erythrocyte sedimentation rate (ESR) performance without exception;3) lower breathing is excluded Road infection, tuberculosis, tumour etc..100 patients are chosen as volunteer, wherein male 44, female 56, the age 11~50 years old, It is divided into two groups, uses conventional medication for control group, uses of the invention for experimental group.Using conventional medication and originally The drug of invention carries out treatment continued treatment and observes 5 months, wherein of the invention 10 doses of traditional Chinese medicine for oral administration are as a treatment course, one day one Agent, takes juice about 600ml twice of decocting, on behalf of the tea;10 days courses for the treatment of of Chinese medicine are sticked, are sticked every time 4-6 hours.Criterion of therapeutical effect are as follows: Cure: dry throat itches, cough and pharyngeal sign all disappears;Effective: dry throat itches, cough and pharyngeal sign is substantially reduced;It is invalid: pharynx It is dry to itch, cough and pharyngeal sign does not improve.It is as follows to obtain table 1:
Male cures number (people) Women cures number (people) It is total to cure number (people) Cure rate (%)
Control group 12 20 32 64%
Experimental group 19 26 45 90%
As seen from the above table, it using traditional Chinese medicine for oral administration of the invention and sticks the treatment laryngeal cough that Chinese medicine combines and has There is very significant curative effect, and the sufferer that the observation discovery by carrying out to healing sufferer 1 year by a definite date is cured is sick without recurrence Example, it was demonstrated that the cure rate of laryngeal cough can be improved in the present invention, and without side-effects.
Typical case
1, Chen, female, 11 years old, patient's dry throat, that is, cough, no phlegm, pharynx hypodynia had burning heat sensation, and wind is then coughed aggravation to the cold, use Traditional Chinese medicine for oral administration of the invention and 2 courses for the treatment of of Chinese medicine application are sticked, clinical symptoms disappear, and physical recovery is normal, then without recurrence.
2, Zhang, female, 25 years old, patient's dry throat larynx was itched, no phlegm, and with pectoralgia is drawn when coughing serious, evil of vomitting encounters peculiar smell stimulation More itch cough, once took anti-inflammatory, cough-relieving, apophlegmatisant, it is ineffective.With traditional Chinese medicine for oral administration of the invention and stick Chinese medicine application 4 afterwards A course for the treatment of, the clinical symptoms such as itch, cough disappear, no relapse in follow-up half a year.
3, Zou, male occur swallowing cough of itching before 46 years old, patient 5 months, have a small amount of phlegm, sometimes dry cough, voluntarily take cough-relieving Apophlegmatisant, symptom are not affected significantly, and are coughed and are aggravated before one week, and irritation dry cough battle array is made, and night more so, seriously affects sleep, With traditional Chinese medicine for oral administration of the invention and 3 courses for the treatment of of Chinese medicine application are sticked afterwards, cough stops, and clinical each symptom disappears, and physical recovery is just Often.
Above description is the detailed description for the present invention preferably possible embodiments, but embodiment is not limited to this hair Bright patent claim, it is all the present invention suggested by technical spirit under completed same changes or modifications change, should all belong to In the covered the scope of the patents of the present invention.

Claims (5)

1. a kind of Chinese medicine composition for oral administration and sticking combination for treating laryngeal cough, which is characterized in that including traditional Chinese medicine for oral administration With stick Chinese medicine, traditional Chinese medicine for oral administration is made of following raw materials according drug: Chinese olive, campanulaceae, Radix Glycyrrhizae, honeysuckle, four number kamuning, dried orange peel, Rhizoma zingiberis, Schisandra chinensis;
It sticks Chinese medicine to be made of following raw materials according drug: blackberry lily, Chinese ephedra, asarum, semen brassicae, perillaseed, indigo naturalis, four number kamuning.
2. the Chinese medicine composition for oral administration and sticking combination for the treatment of laryngeal cough as described in claim 1, which is characterized in that The traditional Chinese medicine for oral administration is by following parts by weight quantity medicine group at 10-20 parts of Chinese olive, 10-20 parts of campanulaceae, 10-15 parts of Radix Glycyrrhizae, gold and silver 10-20 parts of flower, four number kamuning 10-15 parts, 10-15 parts of dried orange peels, 10-20 parts of rhizoma zingiberis, 10-30 parts of Schisandra chinensis;
It is described stick Chinese medicine by following parts by weight quantity medicine group at: 10-30 parts of blackberry lily, 10-30 parts of Chinese ephedra, 10-30 parts of asarum, 10-30 parts of semen brassicae, 10-30 parts of perillaseed, 10-15 parts of indigo naturalis, four kamuning 10-30 parts of numbers.
3. such as the Chinese medicine composition for oral administration and sticking combination of the described in any item treatment laryngeal coughs of claim 1 to 2, Be characterized in that, the traditional Chinese medicine for oral administration the preparation method comprises the following steps:
1) Chinese olive, campanulaceae, Radix Glycyrrhizae, honeysuckle, four number kamuning, dried orange peel, rhizoma zingiberis, Schisandra chinensis are cleaned with clear water respectively, Be placed in shady place dry it is spare;
2) raw material in step 1) is put into container, clear water is added to impregnate 40min-50min;
3) Chinese medicine after impregnating in step 2), which is put, is sequentially placed into frying pan, and a certain amount of clear water is added, and decocts 20min- using intense fire 30min, then turn mild fire decoction 20min-30min after, the screen to filtrate obtains filtrate I and Chinese medicine filter residue, and the filtrate I is stood to normal After warm standby is used, centrifugal treating is carried out using centrifuge, obtaining concentration is 20%-35% concentrate I;
4) the Chinese medicine filter residue in step 3) is placed again into frying pan and is added quantitative clear water, turn text after being heated to boiling Fire decoction 20min-30min, the screen to filtrate obtains filtrate II, by filtrate II use centrifuge carry out the obtained concentration of centrifugal treating for The concentrate II of 35%-55%;
5) step 3) is mixed with concentrate I obtained in step 4) with concentrate II and blender is used to stir 10min- 20min obtains traditional Chinese medicine for oral administration;
It is described stick Chinese medicine the preparation method comprises the following steps:
1) blackberry lily, Chinese ephedra, asarum, semen brassicae, perillaseed, indigo naturalis, four number kamuning are cleaned with clear water respectively, is placed in cool place Dry spare in place;
2) white wine of 45%-65% is uniformly sprayed in the Chinese medicine surface of step 1), and puts and steams 30min-50min into steamer Afterwards, In Shade to air-dry;
3) Chinese medicine after steaming in step 2) is placed in iron pan and stands room temperature after stir-fry to 20min-30min;
4) Chinese medicine in step 3) Jing Guo frying is crushed to the herb powder mixture of 100-120 mesh using pulverizer;
5) honey and transdermal agent azone is added in herb powder mixture described in step 4), and water content is sufficiently stirred to obtain For the Traditional Chinese drug mixture of 30%-45%, and the Traditional Chinese drug mixture is put into die for molding, Chinese medicine must be sticked.
4. the Chinese medicine composition for oral administration and sticking combination for the treatment of laryngeal cough as claimed in claim 3, which is characterized in that The ratio of clear water and Chinese medicine is respectively 1:15 and 1:10 in step 3) and step 4) in the preparation method of the traditional Chinese medicine for oral administration.
5. the Chinese medicine composition for oral administration and sticking combination for the treatment of laryngeal cough as claimed in claim 3, which is characterized in that Mold is circle in step 5) in the preparation method for sticking Chinese medicine, and diameter is 2cm-3cm, with a thickness of 1.5mm- 2.0mm。
CN201811579433.1A 2018-12-24 2018-12-24 A kind of Chinese medicine composition for oral administration and sticking combination for treating laryngeal cough Pending CN109498787A (en)

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CN104337999A (en) * 2013-07-29 2015-02-11 刘笛 Medicine with lung-moistening cough-relieving efficacy and good mouthfeel and application thereof
CN107616501A (en) * 2016-07-15 2018-01-23 珠海宝德润生健康科技有限公司 A kind of composition with clearing lung-heat function and preparation method thereof

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Application publication date: 20190322