CN103784812B - The Chinese medicine for the treatment of asthma - Google Patents

Abstract

The present invention relates to pharmaceutical formulation field, specifically a kind of Chinese medicine treating asthma, is characterized in that, Bulbus Fritillariae Cirrhosae 10～14%, Folium Pyrrosiae 8～12%, Semen Sinapis Albae 6～10%, Herba Epimedii 2～6%, Arisaema Cum Bile 5～7%, Rhizoma Imperatae 2～6%, tylophora florlbunda 2～6%, Flos Gomphrenae 5～7%, Radix Cirsii Japonici 6～10%, Cortex Magnoliae Officinalis 5～7%, Herba Saxifragae 2～6%, Semen Euryales 6～10%, Herba Artemisiae Anomalae 2～5%, Fructus Chebulae 2～6%, Rhizoma Polygonati Odorati 2～6%, Semen Coicis 6～10%, being soaked by above-mentioned 16 taste crude drug, remove slag after decocting to obtain filtered juice. The invention has the beneficial effects as follows, with low cost, have no side effect, exogenous and Intrinsic Bronchial Asthma can be effectively treated.

Description

The Chinese medicine for the treatment of asthma

Technical field

The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of Chinese medicine for treating asthma.

Background technology

It is known that bronchial asthma mainly includes three types, 1. intolerance factors (extrinsic asthma): have the patient of allergic constitution when sucking anaphylaxis antigens particulate or occurring to infect, all can cause morbidity. Sensitinogen mainly sucks pollen, room dirt, demodicid mite, animal soft flocks, industrial dust, fungal spore; Feed fish, Eriocheir sinensis, shrimp, or contact industrial dye etc., also may result in allergy. Immunologic research shows the allergy antigen sucked, and can produce the specificity antibody IgE (IgE) of volume, be attached on mastocyte and the blood basophil of bronchial mucosa. If patient contacts same antigen again, namely antigen be combined with the IgE being attached to mast cell surface, there is anaphylaxis, discharge various bioactivators (such as histamine, 5-hydroxy tryptamine, long response time element, Kallidin I etc.), make bronchial mucosa hyperemia, edema, smooth muscle spasm increases with glandular secretion, bronchioles luminal stenosis, pulmonary ventilation is smooth and difficulty of feeling sleepy, and causes asthma attack. 2. infective agent (intrinsic asthma): by virus or antibacterial, especially viral respiratory tract infection, gradually form and excite asthma extremely common. Sensitinogen ex vivo, for the metabolite of antibacterial or virus, therefore is not removed in time with nose, pharynx, tonsil, lung or other infection focus and is had substantial connection. But excited by infecting at present or to form the mechanism of asthma still not fully aware of. Outside the risk factors such as primary disease is former except contact allergy, respiratory tract infection, every often relevant with weather cataclysm cold and Nervous and Mental Factors. It is complicated through god's character of factor and action pathway, it may be possible to cerebral cortex acts on thalamus, making thalamus changing function and cause vagal being overexcited, secreting acetylcholine, thus adding the tension force of bronchial smooth muscle. 3. inherited genetic factors: asthmatic patient often has familial and heritability.

Summary of the invention

The purpose of the present invention is contemplated to overcome above-mentioned prior art not enough, it is provided that a kind of Chinese medicine for treating asthma, with low cost, have no side effect, and can effectively treat exogenous and Intrinsic Bronchial Asthma. ,

This invention address that above-mentioned technical problem the technical scheme is that a kind of Chinese medicine treating asthma, it is characterized in that, crude drug composition is by weight percentage: Bulbus Fritillariae Cirrhosae 10～14%, Folium Pyrrosiae 8～12%, Semen Sinapis Albae 6～10%, Herba Epimedii 2～6%, Arisaema Cum Bile 5～7%, Rhizoma Imperatae 2～6%, tylophora florlbunda 2～6%, Flos Gomphrenae 5～7%, Radix Cirsii Japonici 6～10%, Cortex Magnoliae Officinalis 5～7%, Herba Saxifragae 2～6%, Semen Euryales 6～10%, Herba Artemisiae Anomalae 2～5%, Fructus Chebulae 2～6%, Rhizoma Polygonati Odorati 2～6%, Semen Coicis 6～10%, above-mentioned 16 taste crude drug are soaked, remove slag after decocting to obtain filtered juice.

The invention has the beneficial effects as follows, with low cost, have no side effect, exogenous and Intrinsic Bronchial Asthma can be effectively treated.

Detailed description of the invention

Below in conjunction with embodiment, the invention will be further described:

Embodiment 1:

Adopting Bulbus Fritillariae Cirrhosae, Folium Pyrrosiae, Semen Sinapis Albae, Herba Epimedii, Arisaema Cum Bile, Rhizoma Imperatae, tylophora florlbunda, Flos Gomphrenae, Radix Cirsii Japonici, Cortex Magnoliae Officinalis, Herba Saxifragae, Semen Euryales, Herba Artemisiae Anomalae, Fructus Chebulae, Rhizoma Polygonati Odorati, Semen Coicis is that crude drug is prepared from, and takes the Bulbus Fritillariae Cirrhosae 12 of cleaning, Folium Pyrrosiae 10, Semen Sinapis Albae 8.1, Herba Epimedii 6.1, Arisaema Cum Bile 4, Rhizoma Imperatae 4, tylophora florlbunda 4, Flos Gomphrenae 6.1, Radix Cirsii Japonici 8.1, Cortex Magnoliae Officinalis 6.1, Herba Saxifragae 4, Semen Euryales 8.1, Herba Artemisiae Anomalae 3.3, Fructus Chebulae 4, Rhizoma Polygonati Odorati 4, Semen Coicis 8.1 in hundred parts of ratios of weight. Take above-mentioned 16 kinds of crude drug gross weights 248 grams. At room temperature 16 taste Chinese herbal medicine are added water to 700～900ml, soak 6～8 hours, then torture about 90～120 minutes with slow fire, remove slag to obtain filtrate about 200ml, medicinal residues add water 300～400ml, torture 40～60 minutes, and remove slag to obtain filtrate 100ml, there are about 300ml medicine soup, namely prepare the Chinese medicine decoction for treating asthma. Every day, potion divided the morning and evening to be administered orally for twice, and each (medicine) being taken before meal 150ml takes 4 months continuously.

Bulbus Fritillariae Cirrhosae clearing heat and moistening lung of the present invention, preventing phlegm from forming and stopping coughing. For lung-heat type cough, the few expectorant of dry cough, deficiency of YIN chronic cough, sputum with blood; Folium Pyrrosiae controls pouring pain, hematuria, lithangiuria, nephritis, metrorrhagia, dysentery, cough due to lung-heat, chronic tracheitis, incised wound, carbuncle; Semen Sinapis Albae is warming the interior apophlegmatisant, and its property is wandered away, and can open lung qi dispersing gas, thoroughly reaches meridians, the expectorant outside outstanding kind cold removing expectorant and flesh side film. Being suitable to cold-phlegm breath with cough, fullness in the chest and hypochondrium pain, expectorant note joint, the joint caused pain of skin, limbs are unfavorable. Also can mass dissipating and swelling eliminating, for carbuncle of yin nature multiple abscess, sucutaneous nodule etc.; Herba Epimedii acrid-sweet flavor, temperature, have effect of kidney invigorating and YANG supporting, expelling wind and removing dampness; Arisaema Cum Bile bitter cold, micro-pungent, cool. Return lung, liver, spleen channel. Removing heat-phlegm, dispelling wind and relieving convulsion. For phlegm-heat cough, cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion; Rhizoma Imperatae is cold in nature, sweet in the mouth. Return lung, stomach, small intestine meridian. There is heat clearing away, diuresis, removing heat from blood, the effect of hemostasis; Tylophora florlbunda, calls Radix tylophorae floribundae, dispelling pathogenic wind and eliminating phlegm, and detoxify dissipating blood stasis. Controlling infantile convulsion, heatstroke is suffered from abdominal pain, asthma productive cough, laryngopharynx swelling and pain, stomachache, toothache, rheumatalgia, traumatic injury; Flos Gomphrenae liver heat removing, eliminating stagnation, relieving cough and relieving asthma. Controlling wind syndrome of head, ophthalmalgia, asthma and cough, dysentery, pertussis, infantile convulsion, scrofula is stolen, skin infection. For chronic or asthmatic bronchitis, pertussis; Radix Cirsii Japonici removing heat from blood, hemostasis, blood stasis dispelling, subduing inflammation. Control haematemesis, epistaxis, hematuria, stranguria with blood, metrorrhagia, leukorrhagia, hemorrhoidal hamorrhage, acute appendicitis, carbuncle and ulcer toxic swelling, furuncle; Cortex Magnoliae Officinalis has dampness, expectorant, removes the effects such as full, the therapeutic method to keep the adverse QI flowing downwards, can be used for treating the diseases such as humidity hysteresis damaging the spleen and stomach, stagnation of QI due to dyspepsia, abdominal distention constipation; Herba Saxifragae is dispeled the wind, heat clearing away, removing pathogenic heat from blood and toxic substance from the body. Controlling rubella, eczema, otitis media, erysipelas, cough is spitted blood, lung abscess, metrorrhagia, haemorrhoids; Semen Euryales reinforcing the kindey to control nocturnal emission, spleen reinforcing stopping leak, promoting diuresis to eliminate damp pathogen. Control seminal emission, stranguria with turbid discharge, leukorrhagia, incontinence of urine, have loose bowels, dysentery, damp arthralgia; Herba Artemisiae Anomalae has hemostasis of curing the wound, and removing blood stasis stimulates the menstrual flow, promoting digestion and removing stagnation, the effect of appetizing of being amusing; Fructus Chebulae astringes the lung, astringing intestine to stop diarrhea, the therapeutic method to keep the adverse QI flowing downwards, sore-throat relieving. Cure mainly: chronic diarrhea, chronic dysentery, proctoptosis, phlegmatic cough of breathing with cough, chronic cough aphonia; Rhizoma Polygonati Odorati nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid. Cough caused by dryness, chronic cough, the dry throat and mouth of calentura the moon liquid consumption wound, interior-heat is quenched one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy dizziness, muscle arteries and veins spasm and pain; Semen Coicis slightly sweet flavor, cool in nature. Return spleen, stomach, lung meridian. There is the function of spleen invigorating eliminating dampness by diuresis, clearing away heat and discharging pus, eliminating impediment, diuretic. The 16 ingenious prescriptions of taste Chinese herbal medicine, scientific compatibility, the mutually coordinated effect of medicine, play the specially good effect of " bronchial asthma " altogether.

The each raw material of the present invention also can the embodiment that mixes of ratio (percentage by weight) listed by according to the form below realize. Its processing technique is identical with embodiment 1.

The present invention is described in further detail by the clinical trial carried out below in conjunction with my institute:

1, case selection: select 80 examples altogether, mean age 16-45 year, wherein female 47 example, male 33 examples, extrinsic bronchial asthma 51 example, Intrinsic Bronchial Asthma 29 example.

2, diagnostic criteria: breathe heavily feel suffocated inverse, rapid breathing, larynx has heavy breathing toot sound, fullness and oppression over the chest like some thing filled, coughs not very, the thin color of thin sputum is white and has foam, dark and greenish complexion, the not thirsty or thirsty desire for hot drinks of mouth. From the beginning of the exterior syndromes such as fever with aversion to cold, lossless headache of holding concurrently, white and slippery fur, stringy and tense pulse or floating tight more.

3, Therapeutic Method: every day, potion divided the morning and evening to be administered orally for twice, each (medicine) being taken before meal 150ml takes 4 months continuously.

4, the standard of curative effect evaluation:

Clinical cure: do not need any medicine, keeps asymptomatic person more than 1 year.

Effective: idol bronchodilatation medicine and alleviate the person of panting.

Effective: wheezing symptoms alleviates to some extent, but often need Drug therapy person.

Invalid: symptom remains unchanged.

5, therapeutic effect: effective 25 examples, effective 46 examples, no effect 9, total effective rate is 88.6%.

Claims (1)

1. treat a Chinese medicine for asthma, it is characterized in that: Bulbus Fritillariae Cirrhosae 10～14%, Folium Pyrrosiae 8～12%, Semen Sinapis Albae 6～10%, Herba Epimedii 2～6%, Arisaema Cum Bile 5～7%, Rhizoma Imperatae 2～6%, tylophora florlbunda 2～6%, Flos Gomphrenae 5～7%, Radix Cirsii Japonici 6～10%, Cortex Magnoliae Officinalis 5～7%, Herba Saxifragae 2～6%, Semen Euryales 6～10%, Herba Artemisiae Anomalae 2～5%, Fructus Chebulae 2～6%, Rhizoma Polygonati Odorati 2～6%, above-mentioned 16 taste crude drug are soaked by Semen Coicis 6～10%, and remove slag after decocting to obtain filtered juice.