CN107648484A - It is a kind of can be with the formula of anti-trioxypurine - Google Patents

It is a kind of can be with the formula of anti-trioxypurine Download PDF

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Publication number
CN107648484A
CN107648484A CN201610594869.2A CN201610594869A CN107648484A CN 107648484 A CN107648484 A CN 107648484A CN 201610594869 A CN201610594869 A CN 201610594869A CN 107648484 A CN107648484 A CN 107648484A
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parts
stem
noble dendrobium
trioxypurine
effect
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周旺
饶远立
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Nanjing Broad Tiandi Biotechnology Co Ltd
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Nanjing Broad Tiandi Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484—Glycyrrhiza (licorice)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/898—Orchidaceae (Orchid family)
    • A61K36/8984—Dendrobium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses it is a kind of can be with the formula of anti-trioxypurine, made of the component containing following parts by weight：15 30 parts of the stem of noble dendrobium, the stem of noble dendrobium spend 20 60 parts, 12 30 parts of sanchi flower, 15 35 parts of Gynostemma pentaphylla, 10 40 parts of akebi, 10 30 parts of desmodium, 5 20 parts of radix glycyrrhizae, lower white 15 35 parts of stone, 10 30 parts of potentilla discolor, 5 20 parts of nervate twayblade herb, 12 30 parts of balsam pear, 10 30 parts of lophatherum gracile, 15 35 parts of cordate houttuynia, 12 30 parts of mulberry leaf.The present invention is developed using a series of pure natural Chinese herbal medicines, is the indispensable important substance of body discharges system without any toxicity and side effects, is had diuresis for antihyperuricemic patient and is promoted the function of releasing uric acid.

Description

It is a kind of can be with the formula of anti-trioxypurine
Technical field
The present invention relates to a kind of medicine, and in particular to it is a kind of can be with the formula of anti-trioxypurine.
Background technology
Hyperuricemia (HUA) refers under normal purine diet state, non-empty stomach serum uric acid level male twice on the same day Higher than 420 μm ol/L, women are higher than 360 μm of ol/L, i.e. referred to as hyperuricemia.Uric acid is the whole last reign of a dynasty of mankind's purine compound Thank to product.Purine metabolic disturbance causes hyperuricemia.This sick illness rate is affected by various factors, with heredity, sex, year Age, life style, eating habit, drug therapy and economic development level etc. are relevant.It is ill according to various regions hyperuricemia in recent years The report of rate, at present China there are about hyperuricemia person 1.2 hundred million, account for the 10% of total population, Gao Fa Nian Ling is middle-aging male And postmenopausal women, but have rejuvenation trend in recent years.
The content of the invention
In view of the above-mentioned state of the art, the technical problems to be solved by the invention are to provide and are made of pure Chinese medicine , there is diuresis for antihyperuricemic patient and promote a kind of the of function of releasing uric acid can be with the formula of anti-trioxypurine.
Technical scheme is used by the present invention solves above-mentioned technical problem：It is a kind of can with the formula of anti-trioxypurine, by containing Made of the component of following parts by weight：Stem of noble dendrobium 15-30 parts, stem of noble dendrobium flower 20-60 parts, sanchi flower 12-30 parts, Gynostemma pentaphylla 15-35 Part, akebi 10-40 parts, desmodium 10-30 parts, radix glycyrrhizae 5-20 parts, lower white 15-35 parts of stone, potentilla discolor 10-30 parts, nervate twayblade herb 5- 20 parts, balsam pear 12-30 parts, lophatherum gracile 10-30 parts, cordate houttuynia 15-35 parts, mulberry leaf 12-30 parts.
Preferred scheme is that the parts by weight composition of its each component is：Stem of noble dendrobium 20-24 parts, stem of noble dendrobium flower 25-38 parts, sanchi flower 18-23 parts, Gynostemma pentaphylla 18-28 parts, akebi 20-28 parts, desmodium 20-22 parts, radix glycyrrhizae 10-13 parts, lower white 20-28 parts of stone, turn over White careless 15-24 parts, nervate twayblade herb 15-20 parts, balsam pear 12-24 parts, lophatherum gracile 18-30 parts, cordate houttuynia 15-30 parts, mulberry leaf 15-25 Part.
Powder, capsule or granule can be made in described medicine.
Powder preparation method：By the stem of noble dendrobium, stem of noble dendrobium flower, sanchi flower, Gynostemma pentaphylla, akebi, desmodium, radix glycyrrhizae, lower stone is white, it is white to turn over Grass, nervate twayblade herb, balsam pear, lophatherum gracile, cordate houttuynia, mulberry leaf weigh in proportion, section, are cleaned, dried with water, beat powder, be put into iron pan Interior slow fire fries 15-25 minutes, treats that color is changed into buff, cools down, and crosses 100-300 mesh sieves, and pouch dispenses after weighing.
Process for producing granula：By the stem of noble dendrobium, stem of noble dendrobium flower, sanchi flower, Gynostemma pentaphylla, akebi, desmodium, radix glycyrrhizae, lower stone is white, turns over White grass, nervate twayblade herb, balsam pear, lophatherum gracile, cordate houttuynia, mulberry leaf weigh in proportion, cut into slices, are cleaned, dried with water, beat powder, be put into iron Slow fire fries 15-25 minutes in pot, treats that color is changed into buff, cools down, and crosses 100-300 mesh sieves, adds 8-10 times of purified water immersion 4-5 hours, extract 2 times, the 1st extraction 3-4 hour, the 2nd extraction 1-2 hour, high speed centrifugation, decoction is concentrated to relatively close 1.15-1.35 is spent, adds auxiliary material, is dried, granulation, is dispensed after weighing.
Capsule preparation method thereof：By the stem of noble dendrobium, stem of noble dendrobium flower, sanchi flower, Gynostemma pentaphylla, akebi, desmodium, radix glycyrrhizae, lower stone is white, it is white to turn over Grass, nervate twayblade herb, balsam pear, lophatherum gracile, cordate houttuynia, mulberry leaf weigh in proportion, section, are cleaned, dried with water, beat powder, be put into iron pan Interior slow fire fries 15-25 minutes, treats that color is changed into buff, cools down, and adds 8 times of purified waters and soaks 3 hours, and 100 DEG C are extracted 3 times, 1st extraction 2 hours, the 2nd extraction 2 hours, the 3rd extraction 1.5 hours, high speed centrifugation remove precipitation, and cryogenic vacuum concentrates It is 1: 1 to decoction and medicinal material ratio, concentrated medicament is 1.10 in 80 DEG C of relative densities, adds auxiliary material, dries, particle, 1g is made Equivalent to 2.5g containing crude drug, post package of weighing enters in capsule.
The technical principle of the present invention：
The effect of stem of noble dendrobium and effect：It is sweet, flat, nontoxic.Cure mainly：In wound, gas under eliminating impediment, tonifying five zang organs consumptive disease is thin thin, Qiang Yin Strengthening the essence.Long term usage, thick stomach.
The effect of stem of noble dendrobium is spent and effect：Qi-regulating is calmed the nerves, moisturizing is preserved youthful looks, improvement is slept, coordinating yin and yang, the strongly fragrant bushing of solution, beneficial blood Promote the production of body fluid, nourishing Yin and moistening lung, nourishing the stomach to improve the production of body fluid, improving eyesight heat-clearing, improve body immunity and other effects, can effectively alleviate that stress is big, body The symptoms such as heart fatigue, the fidgety, insomnia and dreamful sleep of mood.
The effect of sanchi flower and effect：Reducing blood lipid, hypotensive, anticancer, myocardial oxygen delivery ability is improved, strengthen immunity of organism work( Can, it is mainly used in heat-clearing, removing toxic substances, cool blood, decompression, tune fat, immunological regulation, blood circulation and channel invigorating, the anti-ageing, anti-inflammatory analgesic of health etc..
The effect of Gynostemma pentaphylla and effect：Bitter, micro-sweet, it is cool in nature；Return lung, spleen, kidney channel.For treating hypertension, high fat of blood, Coronary heart disease, diabetes, asthma, catarrhal jaundice, antimigraine, anti-decrepit beauty, anticancer, liver cancer, lung cancer, uterine cancer, cutaneum carcinoma, resist Allergy, body-building strength, regulating lipid and reducing weight is fat, shield heart Bao Mai, cerebral tonic tranquillizing, promotees digestion, white hair, has a sleepless night, duodenal ulcer, Hepatitis B, hepatic sclerosis, endocrinopathy, inferior health etc..
The effect of akebi and effect：It is bitter in taste, it is cool.Purging intense heat water-filling.It is promoting blood circulation.Cure mainly hot urination, stranguria with turbid discharge, oedema, It is irritable feverish sensation in chest, larynx numbness pharyngalgia, inflexible pain all over, women's Amenorrhea, alactation.Interior body fluid deficiency, gas is weak without damp and hot, and essence is sliding, the frequency and pregnant of urinating Woman avoids clothes.
The effect of desmodium and effect：It is husky available for heat gonorrhea the effect of removing dampness through diuresis and removing jaundice with clearing heat and detoxicating, eliminating stasis to subdue swelling Leaching, urine is puckery to have a pain, jaundice, carbuncle swells furunculosis, venomous snake bite, liver and bile stone, the disease such as lithangiuria.
The effect of radix glycyrrhizae and effect：For the heart qi deficiency, palpitation and severe palpitation, intermittent pulse, and deficiency of spleen-QI and stomach-QI, lassitude hypodynamia etc.. For having a stomachache, suffering from abdominal pain and gastrocnemius contraction urgency pain etc., the effect of controlling contraction urgency pain, such as Chinese herbaceous peony often can be significantly increased with using with Chinese herbaceous peony Medicine glycyrrhiza decoction.Radix glycyrrhizae has relieving cough and reducing sputum effect, and for tracheitis, coughing with a lot of sputum caused by the disease of pulmonary emphysema is panted, and glutinous phlegm is not easy The diseases such as discharge.For reconciling the strong of some drugses.Such as season CHENGQI TANG this product relax rheum officinale, saltcake discharge function and its Stimulation to intestines and stomach.In addition, this product coordinating the drug actions of a prescription is also commonly used in many prescriptions.
The effect of lower stone is white and effect：Cure mainly puckery intestines；Hemostasis；Prevent prolapse；Hygroscopic sore.Main chronic diarrhea；Protracted dysentery；Under uterine bleeding band； Seminal emission；Sore is not held back.
The effect of potentilla discolor and effect：Treatment dysentery, diarrhoea, leukorrhea, malaria, spit blood, have blood in stool, traumatism and bleeding, dysentery characterized by blood in the stool abdomen Bitterly, protracted dysentery is more than, hemorrhoid hemorrhage, carbuncle sore tumefacting virus.
The effect of nervate twayblade herb and effect：With cooling blood and hemostasis, it is clearing heat and detoxicating the effect of.It is usually used in stomach energy haematemesis, lung heat is coughed up Blood, discharging fresh blood stool, uterine bleeding, operative hemorrhage, traumatic bleeding, sore swollen toxin, venomous snake bite, traumatic injury.
The effect of balsam pear and effect：Mend courage profit liver, diuresis, relieve summer heat, solve spirits, aid digestion, anti-flu, can also control laryngitis and Cough due to wind-heat evil.
The effect of lophatherum gracile and effect：Clearing heat and relieving fidgetness, diuresis.For pyreticosis polydipsia, hot urination leaching pain, aphthae.
The effect of cordate houttuynia and effect：Partially cold and cool, clearing damp and promoting diuresis is most expert at, and can be dried except wind, clearing away heat and eliminating pus, eliminating impediment are stopped Bitterly, it is notable to difficult urination, oedema, tinea pedis and rheumatalgia pain and other effects.
The effect of mulberry leaf and effect：Drunk, dysphoria with smothery sensation is controlled, thirsty, vomiting, difficulty in urination and defecation.
The Chinese medicine composition of the present invention, using the stem of noble dendrobium, stem of noble dendrobium flower, sanchi flower, Gynostemma pentaphylla, akebi, desmodium as main ingredient；It is sweet Careless, lower stone is white, potentilla discolor, nervate twayblade herb, balsam pear are ministerial drug；Lophatherum gracile, cordate houttuynia, mulberry leaf are to make medicine, mediation property of medicine.It is all above Medicine, diuresis is played jointly, accelerates to exclude the function of uric acid.
Present invention tool compared with other products has the advantage that：
The present invention is developed using a series of pure natural Chinese herbal medicines, without any toxicity and side effects, be body discharges system not The important substance that can or lack, there is diuresis for antihyperuricemic patient and promote the function of releasing uric acid.
Embodiment
Treat case：
State of an illness overview：Patient's Mr. Wang, people from Shandong, treated at the beginning of 2 months 2015, at that time with hyperuricemia.
The medicine that treatment is prepared using the present invention：It is a kind of can be with the formula of anti-trioxypurine, by the group containing following parts by weight Made of point：The stem of noble dendrobium, stem of noble dendrobium flower, sanchi flower, Gynostemma pentaphylla, akebi, desmodium, radix glycyrrhizae, lower stone are white, potentilla discolor, nervate twayblade herb, hardship Melon, lophatherum gracile, cordate houttuynia, mulberry leaf weigh in proportion, section, are cleaned, dried with water, beat powder, are put into slow fire in iron pan and fry 15-25 Minute, treat that color is changed into buff, cool down, cross 100-300 mesh sieves, add 8-10 times of purified water immersion 4-5 hour, extract 2 times, 1st extraction 3-4 hour, the 2nd extraction 1-2 hour, high speed centrifugation, decoction is concentrated to relative density 1.15-1.35, added Auxiliary material, dry, granulation, dispensed after weighing.
Treatment method and process：The present invention for oral administration prepare it is a kind of can with the formula of anti-trioxypurine, in the morning, afternoon and evening it is each once, every time One, cooperation daily intakes more than boiling water 250ml.
Patient carrys out further consultation late May, and uric acid in blood content has significantly reduced, and uric acid excludes to work well.Continue to take With the medicine of the present invention, in July, 2015, hyperuricemia is controlled.

Claims (3)

1. a kind of can be with the formula of anti-trioxypurine, it is characterised in that：Made of the component containing following parts by weight：Stem of noble dendrobium 15- 30 parts, stem of noble dendrobium flower 20-60 parts, sanchi flower 12-30 parts, Gynostemma pentaphylla 15-35 parts, akebi 10-40 parts, desmodium 10-30 parts, radix glycyrrhizae 5-20 parts, lower white 15-35 parts of stone, potentilla discolor 10-30 parts, nervate twayblade herb 5-20 parts, balsam pear 12-30 parts, lophatherum gracile 10-30 parts, fish Raw meat grass 15-35 parts, mulberry leaf 12-30 parts.
2. it is according to claim 1 it is a kind of can be with the formula of anti-trioxypurine, it is characterised in that：The parts by weight array of its each component Turn into：Stem of noble dendrobium 20-24 parts, stem of noble dendrobium flower 25-38 parts, sanchi flower 18-23 parts, Gynostemma pentaphylla 18-28 parts, akebi 20-28 parts, desmodium 20-22 parts, radix glycyrrhizae 10-13 parts, lower white 20-28 parts of stone, potentilla discolor 15-24 parts, nervate twayblade herb 15-20 parts, balsam pear 12-24 parts are light Leaf of bamboo 18-30 parts, cordate houttuynia 15-30 parts, mulberry leaf 15-25 parts.
3. it is according to claim 1 it is a kind of can be with the formula of anti-trioxypurine, it is characterised in that：Described medicine can be made scattered Agent, capsule or granule.
CN201610594869.2A 2016-07-26 2016-07-26 It is a kind of can be with the formula of anti-trioxypurine Pending CN107648484A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108991319A (en) * 2018-08-09 2018-12-14 陈文才 One kind purifies the blood careless beverage and its preparation method and application
CN112825946A (en) * 2021-03-05 2021-05-25 山西康寿茶业有限公司 Formula and preparation method of acid clearing tea

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108991319A (en) * 2018-08-09 2018-12-14 陈文才 One kind purifies the blood careless beverage and its preparation method and application
CN112825946A (en) * 2021-03-05 2021-05-25 山西康寿茶业有限公司 Formula and preparation method of acid clearing tea

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Application publication date: 20180202