CN107617098A - One kind treats psoriasic composition - Google Patents
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- CN107617098A CN107617098A CN201711028740.6A CN201711028740A CN107617098A CN 107617098 A CN107617098 A CN 107617098A CN 201711028740 A CN201711028740 A CN 201711028740A CN 107617098 A CN107617098 A CN 107617098A
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Abstract
The present invention relates to drug preparation technique field, more particularly to one kind treats psoriasic composition；Including following raw material by weight：Numb willow root skin 25~35, raw rhizoma zingiberis 25~35, rose of Sharon root skin 25~35, pepper 25~35, buttercup 20~28, herb Potentillae cryptotaeniae 20~28, rootstock jackinthepulpit tuber 10~16, rhizoma arisaematis 10~16, Herba Elephantopi scaberis 10~16, giant salamander oil 10~16；The composition of the present invention passes through with anti-inflammatory, it is promoting blood circulation and removing blood stasis, nti-freckle, detumescence, the medicine of analgesic efficacy are combined, and can effectively reduce the occurrence frequency of psoriasis disease, reach the purpose for the treatment of psoriasis disease, suitable for various psoriasis, composition of the invention, its therapeutic effect is notable, clinical improvement rate is more than 95%, and patient is to drug absorption rate more than 98%.
Description
Technical field
The present invention relates to drug preparation technique field, more particularly to one kind treats psoriasic composition.
Background technology
Psoriasis, it is a kind of common chronic inflammatory dermatoses for being easy to recurrence with characteristic skin lesion.From the beginning of for
Inflammatory red papules, about grain grain gradually expand to mung bean size or fusion turn into brownish red patch, clear border, surrounding later
There is inflammatory blush, substrate infiltration is obvious, the canescence or the silvery white scales of skin that peel off that surface covering multilayer is dried.Gently scraper surface squama
Bits, gradually expose one layer of shinny semitransparent thin film of pale red, claim film phenomenon.Film is struck off again, then small blutpunkte occurs, is claimed
Petechial hemorrhage phenomenon.The white scales of skin that peel off, shinny film and petechial hemorrhage are the key characters for diagnosing psoriasis, and referred to as three levy.Seek
Normal psoriasis pustulosa skin lesion is broadly divided into three periods from occurring to disappear to the end：Enter the departure date, resting stage, catagen, Chu Qiwei
Inflammatory red papules, about grain grain gradually expand to mung bean size or fusion turn into brownish red patch, clear border, surrounding later
There is inflammatory blush, substrate infiltration is obvious, the canescence or the silvery white scales of skin that peel off that surface covering multilayer is dried.Gently scraper surface squama
Bits, gradually expose one layer of shinny semitransparent thin film of pale red, claim film phenomenon.Film is struck off again, then small blutpunkte occurs, is claimed
Petechial hemorrhage phenomenon.The white scales of skin that peel off, shinny film and petechial hemorrhage are the key characters for diagnosing psoriasis, and referred to as three levy.Skin
Disfigurement state：It is point drop-wise, coin shape, map shape, ring-type, banding, general hair property, seborrhea sample, eczema sample, oyster shelly, flat
Liver moss sample, chronic hypertrophic, excipuliform etc..
At present psoriasis by it is light, in, weigh three degree of treatments：Slightly, skin lesion area 10%.External medication is only slightly needed,
In, severe need to be treated with conjoint therapy, including external application foreign object, endo-medicine and physical therapy, and drug therapy more using
Containing the medicine that the excitants such as antibiotic, biological agent are larger, harm to the human body is larger, and because tcm therapy has side effect
Small, anti-recurrence rate effect is good, can stablize the state of an illness, indiffusible feature so that it has been obtained quickly in psoriasis disease field
Using and promote, still, due to the traditional Chinese medical science of the prior art be formulated it is unreasonable, material composition is incorrect, causes current psoriasis
The therapeutic effect of disease is not notable, and cure rate is relatively low.There is the Chinese medicine preparation of research treatment psoriasis disease the country at present, and obtains
Certain effect, such as application number CN201710281144.2 invention《Treat psoriasic Chinese medicine composition》Disclose one kind
Psoriasic Chinese medicine composition is treated, includes the raw material of following parts by weight：Honeysuckle 3-8 parts, windproof 2-6 parts, pawpaw 3-8
Part, coix seed 2-6 parts, akebi 3-8 parts, Radix Angelicae Sinensis 1-5 parts, smilax 3-8 parts, ginseng 1-5 parts, root bark of shaggy-fruited dittany 3-8 parts, snake silk grass 1-
5 parts, root of Dahurain angelica 2-6 parts, radix glycyrrhizae 1-5 parts, fruit of summer cypress 2-6 parts.But because the traditional Chinese medical science of the prior art is formulated unreasonable, raw material
Composition is incorrect, causes that the therapeutic effect of current psoriasis disease is not notable, and improvement rate is relatively low.
The content of the invention
The present invention is in order to solve the above technical problems, providing one kind treats psoriasic composition.
Realized particular by following technical scheme：
One kind treats psoriasic composition, including following raw material by weight：Numb willow root skin 25~35, raw rhizoma zingiberis
25~35, rose of Sharon root skin 25~35, pepper 25~35, buttercup 20~28, herb Potentillae cryptotaeniae 20~28, rootstock jackinthepulpit tuber 10~16, Tian Nan
Star 10~16, Herba Elephantopi scaberis 10~16, giant salamander oil 10~16.
Including following raw material by weight：Numb willow root skin 30, raw rhizoma zingiberis 30, rose of Sharon root skin 30, pepper 30, buttercup
24th, herb Potentillae cryptotaeniae 24, rootstock jackinthepulpit tuber 12, rhizoma arisaematis 12, Herba Elephantopi scaberis 12, giant salamander oil 12.
Described composition, for agent of steeping in wine, oral solutions, pill, paste, lotion.
Described agent of steeping in wine, be after raw material is cleaned, immersion sealed with alcoholic strength >=50%vol white wine, summer extremely
15d is soaked less, at least soaks 30d in the winter time.
Described oral solutions, it is after raw material is weighed, cleans, crush, add the water of 3~4 times of the crushed material quality,
40~50min of infusion is heated, the ethanol of 10 times of amounts of crushed material quality is added, is ultrasonically treated under 45~55KHz frequency
1~2h is stood after 12~18min, ethanol is reclaimed, heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion twice, often
Secondary 30~40min, filtrate three times is mixed to be concentrated into mixes the 1/2 of filtrate volume, adjust the sugar content of concentrate for 20~
30%, packaging.
Described pill, it is to weigh raw material, cleans, crushes, add 18~22% pregelatinized starch of total amount, then use
75% ethanol infiltration, is granulated by comminutor, particle is made, sieved, obtain pill.
Described paste, it is after raw material is weighed, cleans, crush, adds the water of 1~2 times of the crushed material quality, heating
30~40min of infusion, the ethanol of 5 times of amounts of the crushed material quality are added, it is ultrasonically treated 12 under 45~55KHz frequency~
1~2h is stood after 18min, ethanol is reclaimed, heels is continued to heat, infusion obtains the medicinal extract that water content is 15~20%, then adds
Enter 35~40% vaseline of medicinal extract quality, mix, cooling.
Described lotion, it is after raw material is weighed, cleans, crush, adds the water of 2~3 times of the crushed material quality, heating
40~50min of infusion, the ethanol of 5 times of amounts of the crushed material quality are added, it is ultrasonically treated 12 under 45~55KHz frequency~
After 18min stand 1~2h, reclaim ethanol, heels is filtered, obtains filtrate, is being concentrated into the 1/2 of filtrate volume, by concentrate,
The hydrogen peroxide that alcohol that concentration is 30%, concentration are 1~2% is by 1~2：0.18~0.22：0.24~0.28 mass ratio mixing
It is made.
In summary, the beneficial effects of the present invention are：The composition of the present invention is promoting blood circulation and removing blood stasis by with anti-inflammatory, dispels
Spot, detumescence, the medicine of analgesic efficacy are combined, can effectively reduce the occurrence frequency of psoriasis disease, reach treatment psoriasis
The purpose of disease, suitable for various psoriasis, composition of the invention, its therapeutic effect is notable, clinical improvement rate 95% with
On, patient more than 98%, while avoids the pain brought using doctor trained in Western medicine to patient to drug absorption rate, makees after treatment without pair
With Chinese medicine material uneasy to recur and easy to operate while selected is readily available, and cheap.
Embodiment
The embodiment of the present invention is described in further detail below, but the invention is not limited in these realities
Mode is applied, any improvement or replacement on the present embodiment essence spirit, it is claimed to still fall within the claims in the present invention
Scope.
Embodiment 1
One kind treats psoriasic composition, including following raw material by weight：Numb willow root skin 25kg, raw rhizoma zingiberis
25kg, rose of Sharon root skin 25kg, pepper 25kg, buttercup 20kg, herb Potentillae cryptotaeniae 20kg, rootstock jackinthepulpit tuber 10kg, rhizoma arisaematis 10kg, Herba Elephantopi scaberis
10kg, giant salamander oil 10kg.
The psoriasic composition for the treatment of, it is the white of 50%vol with alcoholic strength after raw material is cleaned that its preparation method, which is,
Wine sealing immersion, 15d is at least soaked in summer, at least soaks 30d in the winter time, agent of steeping in wine is made.
Application method：The daily morning and evening takes once respectively, every time 30~40ml.
Embodiment 2
One kind treats psoriasic composition, including following raw material by weight：Numb willow root skin 35kg, raw rhizoma zingiberis
35kg, rose of Sharon root skin 35kg, pepper 35kg, buttercup 28kg, herb Potentillae cryptotaeniae 28kg, rootstock jackinthepulpit tuber 16kg, rhizoma arisaematis 16kg, Herba Elephantopi scaberis
16kg, giant salamander oil 16kg.
The psoriasic composition for the treatment of, its preparation method are after raw material is weighed, and clean, crush, add the powder
The water that 3~4 times of particle quality, infusion 50min is heated, the ethanol of 10 times of amounts of crushed material quality is added, in 55KHz frequency
1~2h is stood after lower supersound process 18min, ethanol is reclaimed, heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion
Twice, each 40min, filtrate three times is mixed and is concentrated into the 1/2 of mixing filtrate volume, and the sugar content for adjusting concentrate is
30%, oral solutions is made in packaging.
Application method：Take respectively once in the morning, afternoon and evening daily, every time 60~70ml.
Embodiment 3
One kind treats psoriasic composition, including following raw material by weight：Numb willow root skin 30kg, raw rhizoma zingiberis
30kg, rose of Sharon root skin 30kg, pepper 30kg, buttercup 24kg, herb Potentillae cryptotaeniae 24kg, rootstock jackinthepulpit tuber 12kg, rhizoma arisaematis 12kg, Herba Elephantopi scaberis
12kg, giant salamander oil 12kg.
The psoriasic composition for the treatment of, its preparation method is to weigh raw material, is cleaned, and crushes, adds total amount
20% pregelatinized starch, then infiltrated with 75% ethanol, it is granulated by comminutor, particle is made, is sieved, obtain pill.
Application method：Take respectively once in the morning, afternoon and evening daily, 1~2 every time.
Embodiment 4
One kind treats psoriasic composition, including following raw material by weight：Numb willow root skin 25kg, raw rhizoma zingiberis
35kg, rose of Sharon root skin 25kg, pepper 35kg, buttercup 20kg, herb Potentillae cryptotaeniae 28kg, rootstock jackinthepulpit tuber 10kg, rhizoma arisaematis 16kg, Herba Elephantopi scaberis
10kg, giant salamander oil 16kg.
The psoriasic composition for the treatment of, its preparation method are after raw material is weighed, and clean, crush, add the powder
The water that 1~2 times of particle quality, infusion 40min is heated, the ethanol of 5 times of amounts of crushed material quality is added, in 45KHz frequency
1~2h is stood after lower supersound process 18min, ethanol is reclaimed, heels is continued to heat, infusion obtains the leaching that water content is 15%
Cream, 40% vaseline of medicinal extract quality is added, mixed, paste is made in cooling.
Application method：Every 2d using once, every time in use, by paste application around psoriatic lesion, adhesive plaster is used
Fixation.
Embodiment 5
One kind treats psoriasic composition, including following raw material by weight：Numb willow root skin 35kg, raw rhizoma zingiberis
25kg, rose of Sharon root skin 35kg, pepper 25kg, buttercup 28kg, herb Potentillae cryptotaeniae 20kg, rootstock jackinthepulpit tuber 10kg, rhizoma arisaematis 16kg, Herba Elephantopi scaberis
10kg, giant salamander oil 12kg.
The psoriasic composition for the treatment of, its preparation method are after raw material is weighed, and clean, crush, add the powder
The water that 2~3 times of particle quality, infusion 50min is heated, the ethanol of 5 times of amounts of crushed material quality is added, in 45KHz frequency
1~2h is stood after lower supersound process 18min, ethanol is reclaimed, heels is filtered, obtains filtrate, is being concentrated into the 1/ of filtrate volume
2, by alcohol that concentrate, concentration are 30%, concentration be 1% hydrogen peroxide by 1：0.22：0.24 mass ratio, which is mixed to prepare, to be washed
Agent.
Application method：Daily cleaning 1~2 time, 3~5min every time, every time in use, lotion is diluted with water into content being
50% solution, is cleaned to affected part, natural air drying, is sure not to be washed out with clear water.
Experimental example
1st, it is some to randomly select the patient of the psoriasis disease of similar symptom, is randomly divided into 5 groups, embodiment 1 is respectively adopted
~5 compositions prepared are treated, and the applicant tracks follow-up, treatment of the patient to medicine are counted, as a result such as the institute of table 1
Show：
Table 1
| Project | Improvement rate % | Drug absorption rate % |
| Embodiment 1 | 95.5 | 98.6 |
| Embodiment 2 | 95.2 | 98.9 |
| Embodiment 3 | 95.3 | 98.3 |
| Embodiment 4 | 95.8 | 98.6 |
| Embodiment 5 | 95.7 | 98.8 |
2nd, efficacy test example：The present invention takes safety, easy to operate, evident in efficacy, efficient high, and is clinical data institute
Prove, the relevant clinical data of the present invention is as follows：
1st, Song：50 years old, man, made a definite diagnosis in November, 2015 with homeliness type psoriasis, using the therapeutic modality of doctor trained in Western medicine,
3 months are continue for, during which recurrent exerbation, after using average 15d by top, erythema is reduced, and is continued after taking 1 course for the treatment of, old rash
Disappear, occur without new rash, no rebound phenomenon, each course for the treatment of one month.
2nd, money so-and-so：40 years old, man, make a definite diagnosis in January, 2014 with making a definite diagnosis with joint type psoriasis, using the treatment of doctor trained in Western medicine
Mode, half a year is continue for, during which recurrent exerbation, after using a course for the treatment of by top, pain slows down, and redness disappears, and old rash disappears
Lose, occur without new rash, no rebound phenomenon, each course for the treatment of one month.
3rd, Mr. Wang：45 years old, female was made a definite diagnosis in March, 2015 with erythrodermic psoriasis, using western medical treatment mode,
Half a year is continue for, during which recurrent exerbation, after taking two courses for the treatment of by top, flush phenomenon disappears, and lymph caking disappears, after
Continue after taking 1 course for the treatment of, pain disappears, and does not recur again, each course for the treatment of one month.
So far, patient body is healthy always for the present inventor's follow-up, and the incidence of disease persistently reduces, wherein, improvement rate 98% with
On, no rebound phenomenon.
Claims (8)
1. one kind treats psoriasic composition, it is characterised in that including following raw material by weight：Numb willow root skin 25~
35th, raw rhizoma zingiberis 25~35, rose of Sharon root skin 25~35, pepper 25~35, buttercup 20~28, herb Potentillae cryptotaeniae 20~28, rootstock jackinthepulpit tuber 10
~16, rhizoma arisaematis 10~16, Herba Elephantopi scaberis 10~16, giant salamander oil 10~16.
2. psoriasic composition is treated as claimed in claim 1, it is characterised in that including following original by weight
Material：Numb willow root skin 30, raw rhizoma zingiberis 30, rose of Sharon root skin 30, pepper 30, buttercup 24, herb Potentillae cryptotaeniae 24, rootstock jackinthepulpit tuber 12, rhizoma arisaematis 12,
Herba Elephantopi scaberis 12, giant salamander oil 12.
3. psoriasic composition is treated as claimed in claim 1, it is characterised in that described composition, for agent of steeping in wine, mouth
Take liquor, pill, paste, lotion.
4. psoriasic composition is treated as claimed in claim 3, it is characterised in that described agent of steeping in wine, is to wash raw material
After net, immersion is sealed with alcoholic strength >=50%vol white wine, 15d is at least soaked in summer, at least soaks 30d in the winter time.
5. psoriasic composition is treated as claimed in claim 3, it is characterised in that described oral solutions, be by raw material
After weighing, clean, crush, add the water of 3~4 times of the crushed material quality, heat 40~50min of infusion, add the crushing
Expect the ethanol of 10 times of amounts of quality, stand 1~2h after 12~18min is ultrasonically treated under 45~55KHz frequency, reclaim ethanol,
Heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion twice, 30~40min, filtrate will mix concentration three times every time
To mixing the 1/2 of filtrate volume, the sugar content for adjusting concentrate is 20~30%, packaging.
6. psoriasic composition is treated as claimed in claim 3, it is characterised in that described pill, it is to weigh raw material,
Clean, crush, add 18~22% pregelatinized starch of total amount, then infiltrated with 75% ethanol, be granulated, made by comminutor
Into particle, sieving, pill is obtained.
7. psoriasic composition is treated as claimed in claim 3, it is characterised in that described paste, be to weigh raw material
Afterwards, clean, crush, add the water of 1~2 times of the crushed material quality, heat 30~40min of infusion, add the crushed material matter
The ethanol of 5 times of amounts of amount, 1~2h is stood after 12~18min is ultrasonically treated under 45~55KHz frequency, ethanol is reclaimed, by remnants
Material continues to heat, and infusion obtains the medicinal extract that water content is 15~20%, adds 35~40% vaseline of medicinal extract quality, mixes
It is even, cooling.
8. psoriasic composition is treated as claimed in claim 3, it is characterised in that described lotion, be to weigh raw material
Afterwards, clean, crush, add the water of 2~3 times of the crushed material quality, heat 40~50min of infusion, add the crushed material matter
The ethanol of 5 times of amounts of amount, 1~2h is stood after 12~18min is ultrasonically treated under 45~55KHz frequency, ethanol is reclaimed, by remnants
Material filtering, obtains filtrate, is being concentrated into the 1/2 of filtrate volume, is 1~2% by alcohol that concentrate, concentration are 30%, concentration
Hydrogen peroxide presses 1~2：0.18~0.22：0.24~0.28 mass ratio is mixed to prepare.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711028740.6A CN107617098A (en) | 2017-10-29 | 2017-10-29 | One kind treats psoriasic composition |
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| CN201711028740.6A CN107617098A (en) | 2017-10-29 | 2017-10-29 | One kind treats psoriasic composition |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113730457A (en) * | 2020-05-28 | 2021-12-03 | 怀殿芳 | External-use pharmaceutical composition for psoriasis and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107050137A (en) * | 2017-03-29 | 2017-08-18 | 贵州银老太侗医药有限公司 | A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof |
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2017
- 2017-10-29 CN CN201711028740.6A patent/CN107617098A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107050137A (en) * | 2017-03-29 | 2017-08-18 | 贵州银老太侗医药有限公司 | A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 贾民勇等: "《家庭健康增益计划》", 31 December 2011, 中国古籍出版社 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113730457A (en) * | 2020-05-28 | 2021-12-03 | 怀殿芳 | External-use pharmaceutical composition for psoriasis and preparation method thereof |
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Application publication date: 20180123 |