CN107050137A - A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof - Google Patents

A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof Download PDF

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Publication number
CN107050137A
CN107050137A CN201710199874.8A CN201710199874A CN107050137A CN 107050137 A CN107050137 A CN 107050137A CN 201710199874 A CN201710199874 A CN 201710199874A CN 107050137 A CN107050137 A CN 107050137A
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China
Prior art keywords
shoulder
composition
neck
disc disease
lumbar disc
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CN201710199874.8A
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李邦富
李劲诚
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Guizhou Silver Lao Dong Pharmaceutical Co Ltd
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Guizhou Silver Lao Dong Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
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    • A61K36/539—Scutellaria (skullcap)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714—Aconitum (monkshood)
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
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Abstract

The present invention relates to drug preparation technique field, more particularly to a kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof；It is made up of following raw material by weight：White wine, levisticum, bark of ash, geranium wilfordii, frankincense, myrrh, the root of Dahurain angelica, monkshood, Herba Siegesbeckiae, honeysuckle, river ox paint, Ligusticum wallichii, erythrina bark, safflower, radix scutellariae, notopterygium root, Radix Aconiti Kusnezoffii, the raw Radix Astragali, schizonepeta；The composition of the present invention passes through with clearing heat and detoxicating, it is promoting blood circulation and removing blood stasis, wind-damp dispelling, detumescence, the medicine of analgesic efficacy are combined so that composition, which has, promotes channels and collaterals, blood circulation, effect promoting blood circulation and removing blood stasis, the occurrence frequency of neck, shoulder, lumbar disc disease can effectively be reduced, treatment neck, shoulder, the purpose of lumbar disc disease are reached, significantly, clinical improvement rate is more than 80% for its therapeutic effect.

Description

A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof
Technical field
The present invention relates to drug preparation technique field, more particularly to it is a kind of treat neck, shoulder, the composition of lumbar disc disease and its Preparation method.
Background technology
Cervical spondylopathy, also known as cervical spine syndrome, are osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, cervical vertebra The general name of Spondylosis disease, is a kind of illness that basis is changed into cervical vertebra degeneration pathology.Strained for a long time mainly due to cervical vertebra, There is cervical vertebra degeneration and trigger the vertebra section unstability of cervical vertebra, loosen；Nucleus pulposus is protruded or deviate from；Spur is formed；Ligament Plump and calcification；Spinal canal stenosis of Secondary cases etc., stimulates or has oppressed neighbouring nerve root, spinal cord, vertebral artery and neck sympathetic Nerve etc. is organized, and causes the syndrome of various sings and symptoms, here it is cervical spondylopathy；Scapulohumeral periarthritis " is also known as shoulder joint group Inflammation is knitted, this is the chronic inflammation of the soft tissues such as shoulder muscle, tendon, synovial bursa and capsular ligament, the people of 50 years old or so is relatively common.Cause For office staff due to bending over one's desk working for a long time, the muscle ligament of shoulder is in tense situation, so the right side of fifty people In quite a few see.The traditional Chinese medical science thinks this disease caused by shoulder is affected by the cold, and because ill metathorax shoulder joint is stiff, limitation of activity is good As having freezed, so claiming " frozen shoulder ", " scapulohumeral periarthritis ", the characteristics of incidence of scapulohumeral periarthritis is chronic process：Initial stage is inflammatory phase, Shoulder pain unbearably, especially using night as very.Sleep stands up difficulty, gnawing pains take no rest, it is impossible to enter often because of the squashy and specific clinostatism of shoulder Sleep.If initial therapy is improper, it will gradually develop into shoulder mobility and be limited, it is impossible to be upper to lift, in freezing shape.Often influence daily life It is living, have a meal and wear the clothes, wash one's face to comb one's hair and feel difficult.Can't take care of oneself when serious, shoulder arm part muscle also can atrophy, patient is extremely Pain；The protrasion of the lumbar intervertebral disci refers to after interverbebral disc aging that elasticity reduction causes Anular disruption, marrow under certain factor Core is extruded out, and compressing stimulates peripheral nerve root blood vessel, and the diseases such as pain fiber crops occurs, and waist is bent in tear sample severe pain during morbidity Pain relief after knee is lain up, activity or cough, sneeze, but the pain increased, and along sciatic nerve passing line to leg Radiate in portion, hence it is evident that the longer patient of the limited course of disease, it is numb that lower limb have Rediating Pain to merge.There is 85% case to cause ischium in patient Neuralgia.The reason for this disease is prominent is mainly intervertebral disc degeneration, typically after 20 years old, and interverbebral disc starts to degenerate, loss of moist, Gradually attenuating disc tissue itself lacks blood supply to fiber annularligament elasticity, and repair ability is poor, adds heavy burden greatly, activity It is many, wound is run into, the strain of accumulation property causes Anular disruption.Long-term lumbar muscle strain, muscle and ligament atrophy, tonicity enhancing, Increase the internal pressure of interverbebral disc, be also to cause Anular disruption, Nucleus pulposus major reason.The traditional Chinese medical science thinks that this disease is mainly liver kidney Deficient, qi depression to blood stasis, injury of tendon and muscle bone is wrong, and wind-cold damp pathogen is taken advantage of a weak point in opponent's defence invasion and attack human body, miasma resistance channels and collaterals and fallen ill, and can be had using treatment by Chinese herbs Preferable clinical effectiveness.At present, doctor trained in Western medicine for the medicine that uses neck, shoulder, the treatment of lumbar disc disease more with antibiotic, hormone, only Based on pain agent, physiotherapy, though so contributing to rapid recovery, slows down pain, its is short-term with partial insulation, physiotherapy, acupuncture, massage Effect still, but can not remove root.Drug therapy is carried out for the more long patient of stadium, but prolonged administration of drugs can not only be produced The raw resistance to the action of a drug, can also produce such as gastrointestinal function damage, osteoporosis, endocrine disturbance, nervous system disorders and cortin work( Hyperfunction adverse reaction can be waited, and can not thoroughly remove root, and use physiotherapy, then need to adhere to for a long time, it is impossible to interrupt, but be not easy to Radical cure, and because tcm therapy has Small side effects, anti-recurrence rate effect is good, can stablize the state of an illness, indiffusible feature so that its Quick application and popularization are obtained in neck, shoulder, lumbar disc disease field, still, because traditional Chinese medical science formula of the prior art does not conform to Reason, material composition is incorrect, causes that the therapeutic effect of current neck, shoulder, lumbar disc disease is not notable, and cure rate is relatively low.It is domestic at present There are research treatment neck, shoulder, the Chinese medicine preparation of lumbar disc disease, and achieve certain effect, such as application number CN200710011201.1 invention《It is a kind of to treat the de- medicine of neck, shoulder, ridge, lumbar vertebrae, waist》Disclose the root of Chinese clematis, it is POXUE DAN, grey Art, the red sage root, peach kernel, cultivated land, Cocculus trilobus, Radix Angelicae Sinensis, the root of herbaceous peony, Ligusticum wallichii, Job's tears, corydalis tuber, levisticum, Divine Comedy, felwort, scorpio, safflower, The bark of eucommia, frankincense, psoralea corylifolia, myrrh, RADIX ACONITILATERALIS PREPARATA, Rhizoma Arisaematis (processed), Chinese cassia tree, the root of Dahurain angelica, cassia twig, golden cypress, notopterygium root Chinese medicine preparation treatment neck, Shoulder, ridge, lumbar vertebrae, waist take off；Such as application number CN201210447004.5 invention《Treat cervical spondylopathy, protrusion of lumber intervertebral disc, scapulohumeral periarthritis Chinese medicine and preparation method thereof》Disclose intricate clematis herb, lycopodium calvatum, the root of Chinese clematis, erythrina bark, cortex acanthopanacis, the rhizome of davallia, Rhizoma Sparganii, Chinese medicine preparation treatment treatment cervical spondylopathy, protrusion of lumber intervertebral disc, the scapulohumeral periarthritis of dragon's blood.But, because the traditional Chinese medical science of the prior art is matched somebody with somebody Side is unreasonable, and material composition is incorrect, causes that the therapeutic effect of current neck, shoulder, lumbar disc disease is not notable, and improvement rate is relatively low.
The content of the invention
The present invention there is provided a kind of in order to solve the above technical problems, treat neck, shoulder, the composition of lumbar disc disease and its preparation Method.
Realized particular by following technical scheme：
A kind of composition for treating neck, shoulder, lumbar disc disease, including following raw material by weight：Levisticum 10~20, the Qin Macrophylla 10~15, geranium wilfordii 8~12, frankincense 8~12, myrrh 8~12, the root of Dahurain angelica 10~20, monkshood 8~12, Herba Siegesbeckiae 10~20, gold Honeysuckle flower 15~25, river ox paint 10~20, Ligusticum wallichii 25~35, erythrina bark 10~20, safflower 10~15, radix scutellariae 8~12, notopterygium root 15~ 25th, Radix Aconiti Kusnezoffii 4~8, the raw Radix Astragali 45~55, schizonepeta 10~20.
Preferably, including following raw material by weight：Levisticum 15, bark of ash 13, geranium wilfordii 10, frankincense 10, myrrh 10, The root of Dahurain angelica 15, monkshood 10, Herba Siegesbeckiae 15, honeysuckle 20, river ox paint 15, Ligusticum wallichii 30, erythrina bark 15, safflower 13, radix scutellariae 10, notopterygium root 20th, Radix Aconiti Kusnezoffii 6, the raw Radix Astragali 50, schizonepeta 15.
Described composition, is oral formulations, is preferably steep in wine, oral liquid, tablet, pill or capsule.
Described steeps in wine, and is after raw material is cleaned, to be sealed and soaked with white wine, 15d is at least soaked in summer, in the winter time at least Soak 30d.
Described white wine, is the white wine brewed with single grain, its alcoholic strength >=50%vol.
Described oral liquid, is after raw material is weighed, to clean, add water infusion three times, and each 30min mixes three filtrates Close, add the ethanol of 5 times of amounts of mixing filtrate gross mass, reclaim after ethanol, add monose, the sugar content of regulation residual solution is 20 ~30%, packaging.
Described tablet, is after raw material is weighed, to clean, crushes, add water to cook into the medicinal extract that water content is 12~15%, 18~25% amylum pregelatinisatum of medicinal extract quality is added, then is infiltrated with 65% ethanol, 0.5% stearic acid of total amount is added Magnesium is mixed, tabletted by tablet press machine, obtains tablet.
Described pill, is to weigh raw material, is cleaned, and is crushed, and adds 18~25% pregelatinized starch of total amount, then is used 75% ethanol infiltration, is granulated by comminutor, particle is made, sieved, obtain pill.
Described capsule, is to weigh raw material, is cleaned, and is crushed, then with methylcellulose or alginates or poly- second Capsulae vacuus prepared by enol or metagelatin is wrapped up, and is prepared into capsule.
The Chinese medicine that the present invention is used has following effect：
Levisticum：Pungent, hardship, slightly warm in nature, with dispelling wind and eliminating dampness, effect of arthritis analgesic, for wind-cold-dampness arthralgia, few the moon lies prostrate wind Headache, chill holds wet headache under the arm.
Bark of ash：Pungent, hardship, puts down, with wind-damp dispelling, clearing away damp-heat, effect of stopping numbness pain, for muscle arteries and veins contraction, skeletal pain, day Late afternoon hectic fever, infantile malnutrition generates heat.
Geranium wilfordii：With wind-dispelling, promoting blood circulation, clearing heat and detoxicating effect, for rheumatalgia pain, contraction, ulcer, bruise, Enteritis, dysentery.
Frankincense：Pungent, hardship, temperature, with blood-activating and qi-promoting analgesic, effect of detumescence and promoting granulation, for chest impediment and cardialgia, gastral cavity pain, Dysmenorrhoea Amenorrhea, postpartum stasis, abdominal mass stomachache, arthralgia pain due to rheumatism, muscle arteries and veins contraction, traumatic injury, carbuncle swells sore.
Myrrh：Pungent, hardship, the scattered stasis pain having, detumescence and promoting granulation effect, for chest impediment and cardialgia, gastral cavity pain, dysmenorrhoea warp Close postpartum stasis , Disorder lump in the abdomen is suffered from abdominal pain, arthralgia pain due to rheumatism, traumatic injury, the treatment of the illness such as carbuncle swells sore.
The root of Dahurain angelica：It is pungent, temperature, with wind-dispelling, eliminating dampness is subsided a swelling, effect of analgesic, for having a headache, pain in the supra-orbital bone, dentalgia, nasosinusitis, Cold-dampness stomachache, intestines wind anal fistula, leukorrhea with reddish discharge, ulcer sores, skin itchy, mange.
Monkshood：With dispelling wind and eliminating dampness, effect of antalgic, for wind-cold-dampness arthralgia, arthralgia, trusted subordinate's crymodynia, cold hernia Have a pain.For treating the illnesss such as wind-cold-dampness arthralgia, arthralgia.
Herba Siegesbeckiae：With wind-damp dispelling, degrading the channel, clearing heat and detoxicating effect, for arthralgia pain due to rheumatism, stiffness of muscle and joint, waist and knee without Power, hemiplegia, high blood pressure, malaria, jaundice, carbuncle swells, sore, rubella wet sore, insect and animal biting.
Honeysuckle：Have effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treat wind, cure mainly disease under turgor, warm disease heating, heat toxin carbuncle The disease such as ulcer and tumour.Its for dizzy dizziness, thirst, hidrosis unhappiness, enteritis, bacillary dysentery, measles, pneumonia, encephalitis, epidemic meningitis, The illnesss such as acute mastitis, septicemia, appendicitis, skin infection, ulcer furunculosis, erysipelas, parotitis, suppurative tonsillitis are equal There is certain curative effect
River ox paint：It is easing joint movement with dispelling stasis of blood and stimulating the menstrual flow, effect of inducing diuresis for treating strangurtia.For Amenorrhea abdominal mass, placenta retension is closed Save numbness pain, sufficient impotence muscle contraction, cards such as hematuria blood drenches, injury from falling down
Ligusticum wallichii：With promote breath and open depression, method wind-dryness is wet, effect of promoting blood circulation and stopping pain, dizzy for air-cooled headache rotation, hypochondriac pain abdomen pain, Arthritis muscle contraction, Amenorrhea, difficult labour, postpartum stasis block pain, ulcer sores.For irregular menstruation, closed dysmenorrhea, lump in the abdomen stomachache, chest side of body thorn Bitterly, tumbling and swelling, headache, arthralgia pain due to rheumatism.
Erythrina bark：With dispelling wind and eliminating dampness；Water profitting；Effect of promoting blood circulation and detoxication, for rheumatic arthritis；Waist and leg ache； Edema due to deficiency of the kidney；Quench one's thirst；Epigastric pain；Traumatic injury；Fracture；Spit blood；Bleeding from five sense organs or subcutaneous tissue；Malaria；Dermatitis rhus；Osteomyelitis；Deep purulence ulcer.
Safflower：With invigorate blood circulation, effect of stasis eliminatings analgesic, for Amenorrhea, abdominal mass is had difficult labour, stillborn foetus, and lochia is not Row, hemostasis are had a pain, carbuncle swells, injury from falling down.
Notopterygium root：Scattered exterior cold, wind-damp dispelling, sharp joint, cure cold chill, and lossless, wind-cold-dampness arthralgia of having a headache, item strengthening tendons is anxious, joint Ache, geomantic omen edema, skin sore.
Radix Aconiti Kusnezoffii：With dispelling wind and eliminating dampness, effect of antalgic, for wind-cold-dampness arthralgia, arthralgia, trusted subordinate's crymodynia is trembled with fear Hernia is had a pain, narcotic analgesic.
Schizonepeta：There is wind-dispelling, inducing diaphoresis, promoting eruption, hemostasis, for cold, fever, have a headache, eye itching, measles, carbuncle swells, Sore scabies, rubella.
In summary, the beneficial effects of the present invention are：The composition of the present invention passes through with clearing heat and detoxicating, promoting blood circulationization The stasis of blood, wind-damp dispelling, detumescence, the medicine of analgesic efficacy are combined so that composition, which has, promotes channels and collaterals, blood circulation, promoting blood circulationization The effect of the stasis of blood, can effectively reduce the occurrence frequency of neck, shoulder, lumbar disc disease, reach treatment neck, shoulder, the purpose of lumbar disc disease, this hair Bright composition, significantly, clinical improvement rate is more than 80% for its therapeutic effect, while avoiding using doctor trained in Western medicine and physiotherapy to patient Had no side effect after the pain brought, treatment, it is uneasy to recur and easy to operate, while selected Chinese medicine material is readily available, And it is cheap.
The white wine that the present composition is prepared using pure grain through distillation, soaks to Chinese medicine material, passes through high concentration The immersion of white wine, the nutriment in Chinese medicine is soaked out to come, when being treated to patient, and significantly, improvement rate is high for effect.
Embodiment
The embodiment to the present invention is described in further detail below, but the invention is not limited in these realities Mode is applied, any improvement or replacement on the present embodiment essence spirit still falls within the claims in the present invention claimed Scope.
Embodiment 1
A kind of composition for treating neck, shoulder, lumbar disc disease, is made up of following raw material by weight：White wine 900g, solely 10g living, bark of ash 10g, geranium wilfordii 8g, frankincense 8g, myrrh 8g, root of Dahurain angelica 10g, monkshood 8g, Herba Siegesbeckiae 10g, honeysuckle 15g, river ox Paint 10g, Ligusticum wallichii 25g, erythrina bark 10g, safflower 10g, radix scutellariae 8g, notopterygium root 15g, Radix Aconiti Kusnezoffii 4g, raw Radix Astragali 45g, schizonepeta 10g.
After raw material is cleaned, sealed and soaked with alcoholic strength >=50%vol white wine, 15d is at least soaked in summer, in the winter time At least soak 30d.
Instructions of taking：Respectively take once in the morning, afternoon and evening, every time 40~60ml.
Embodiment 2
A kind of composition for treating neck, shoulder, lumbar disc disease, is made up of following raw material by weight：White wine 1100g, Levisticum 20g, bark of ash 15g, geranium wilfordii 12g, frankincense 12g, myrrh 12g, root of Dahurain angelica 20g, monkshood 12g, Herba Siegesbeckiae 20g, honeysuckle 25g, river ox paint 20g, Ligusticum wallichii 35g, erythrina bark 20g, safflower 15g, radix scutellariae 12g, notopterygium root 25g, Radix Aconiti Kusnezoffii 8g, raw Radix Astragali 55g, chaste tree Mustard 20g.
After raw material is cleaned, sealed and soaked with alcoholic strength >=50%vol white wine, 15d is at least soaked in summer, in the winter time At least soak 30d.
Instructions of taking：Respectively take once in the morning, afternoon and evening, every time 40~60ml.
Embodiment 3
A kind of composition for treating neck, shoulder, lumbar disc disease, is made up of following raw material by weight：White wine 1000g, Levisticum 15g, bark of ash 13g, geranium wilfordii 10g, frankincense 10g, myrrh 10g, root of Dahurain angelica 15g, monkshood 10g, Herba Siegesbeckiae 15g, honeysuckle 20g, river ox paint 15g, Ligusticum wallichii 30g, erythrina bark 15g, safflower 13g, radix scutellariae 10g, notopterygium root 20g, Radix Aconiti Kusnezoffii 6g, raw Radix Astragali 50g, chaste tree Mustard 15g.
After raw material is cleaned, sealed and soaked with alcoholic strength >=50%vol white wine, 15d is at least soaked in summer, in the winter time At least soak 30d.
Instructions of taking：Respectively take once in the morning, afternoon and evening, every time 20~30ml.
Embodiment 4
A kind of composition for treating neck, shoulder, lumbar disc disease, is made up of following raw material by weight：White wine 900g, solely 10g living, bark of ash 10g, geranium wilfordii 12g, frankincense 12g, myrrh 8g, root of Dahurain angelica 10g, monkshood 12g, Herba Siegesbeckiae 20g, honeysuckle 15g, river Ox paint 10g, Ligusticum wallichii 35g, erythrina bark 20g, safflower 10g, radix scutellariae 8g, notopterygium root 25g, Radix Aconiti Kusnezoffii 8g, raw Radix Astragali 55g, schizonepeta 10g.
It is after raw material is weighed, to clean, add water infusion three times, each 30min, three filtrates is mixed, adds mixing filter The ethanol of 5 times of amounts of liquid gross mass, is reclaimed after ethanol, adds monose, the sugar content of regulation residual solution is 20~30%, and packaging is Obtain oral liquid.
Instructions of taking：Respectively take once in the morning, afternoon and evening, every time 30~40ml.
Embodiment 5
A kind of composition for treating neck, shoulder, lumbar disc disease, is made up of following raw material by weight：White wine 1100g, Levisticum 10g, bark of ash 15g, geranium wilfordii 8g, frankincense 12g, myrrh 8g, root of Dahurain angelica 20g, monkshood 8g, Herba Siegesbeckiae 20g, honeysuckle 15g, river Ox paint 20g, Ligusticum wallichii 35g, erythrina bark 10g, safflower 15g, radix scutellariae 8g, notopterygium root 25g, Radix Aconiti Kusnezoffii 4g, raw Radix Astragali 55g, schizonepeta 10g.
It is after raw material is weighed, to clean, crushes, adds water to cook into the medicinal extract that water content is 12~15%, add medicinal extract matter 18~25% amylum pregelatinisatum of amount, then infiltrated with 65% ethanol, 0.5% magnesium stearate for adding total amount is mixed, and is led to Cross tablet press machine tabletted, obtain 300, tablet.
Instructions of taking：Respectively take once in the morning, afternoon and evening, warm water is swallowed, 1 tablet once.
Embodiment 6
A kind of composition for treating neck, shoulder, lumbar disc disease, is made up of following raw material by weight：Levisticum 10g, the Qin Macrophylla 15g, geranium wilfordii 8g, frankincense 12g, myrrh 12g, root of Dahurain angelica 20g, monkshood 8g, Herba Siegesbeckiae 10g, honeysuckle 15g, river ox paint 20g, Ligusticum wallichii 25g, erythrina bark 20g, safflower 15g, radix scutellariae 12g, notopterygium root 15g, Radix Aconiti Kusnezoffii 4g, raw Radix Astragali 45g, schizonepeta 10g.
To weigh raw material, clean, crush, add total amount 18~25% pregelatinized starch, then with 75% ethanol Infiltration, is granulated by comminutor, particle is made, and is sieved, is obtained pill 600.
Instructions of taking：Respectively take once in the morning, afternoon and evening, warm water is swallowed, 2 every time.
Embodiment 7
A kind of composition for treating neck, shoulder, lumbar disc disease, including following raw material by weight：Levisticum 15g, bark of ash 13g, geranium wilfordii 10g, frankincense 10g, myrrh 10g, root of Dahurain angelica 15g, monkshood 1g, Herba Siegesbeckiae 15g, honeysuckle 20g, river ox paint 15g, river Rhizome of chuanxiong 30g, erythrina bark 15g, safflower 13g, radix scutellariae 10g, notopterygium root 20g, Radix Aconiti Kusnezoffii 6g, raw Radix Astragali 50g, schizonepeta 15g.
It is to weigh raw material, cleans, crushes, then with methylcellulose or alginates or polyvinyl alcohol or metagelatin The capsulae vacuus of preparation is wrapped up, and is prepared into capsule 500.
Instructions of taking is：Respectively take once in the morning, afternoon and evening, warm water is swallowed, 1~2 every time.
Experimental example
1st, toxicity test：
1.1 medicine：Using any combination thing of embodiment 1~7.
1.2nd, subjects：Choose the small white mouse 100 of health health, male and female half and half, body weight 10-15g, artificial Breeding observing 3d under 12h, ventilation condition good situations is illuminated, 2 groups are randomly divided into, one of which is blank control examination group, administration Forbid within 4 hours feed after preceding 12h and administration, but can't help water.
1.3rd, method：After 3d, except blank group, another set small white mouse is gavaged dosage for 0.05ml/g, implementation Any combination thing of example 1~7, observes 7d.
1.4th, result：Continuous Observation 7d, whole small white mouses are good for the spirit of living and whole small white mouses, appetite, secretion, exhaled Do not observe exception in terms of suction, eye, by experiment mice and control group mice after analysing, each histoorgan is without obvious sense Difference, cores, liver, spleen, lung, kidney and intestines make pathological section also without significantly different, increased dosage amount, same method gavages embodiment 1~7 any combination thing, whole mouse are still good for and lived, and are compared without exception with control group, illustrate said composition to mouse safety It is nontoxic.
2nd, the patient for randomly selecting the cervical spondylosis, scapulohumeral periarthritis disease, lumbar disc disease in identical sick age is some, is randomly divided into 7 Group, the composition that the preparation of embodiment 1~7 is respectively adopted is treated, the applicant's tracking follow-up, suction of the statistics patient to medicine Receipts situation, as a result as shown in table 1：
Table 1
Project The absorptivity % of the patient in 1 year sick age The absorptivity % of the patient in 2 years sick ages
Embodiment 1 94.5 93.6
Embodiment 2 94.5 93.9
Embodiment 3 94.8 94.3
Embodiment 4 94.4 93.6
Embodiment 5 94.7 93.3
Embodiment 6 94.6 92.8
Embodiment 7 94.5 93.1
Explanation：The present invention is oral formulations, is preferably steep in wine, oral liquid, tablet, pill or capsule, by 1 pair one of table From the point of view of the absorbing state of age patient and two age patients, the effect steep in wine is substantially better than other formulations.
2nd, efficacy test example：The present invention takes safety, easy to operate, evident in efficacy, efficient high, and is clinical data institute Prove, the relevant clinical data of the present invention is as follows：
1st, Song：45 years old, man was made a definite diagnosis with scapulohumeral periarthritis, the treatment being combined using doctor trained in Western medicine, physiotherapy in November, 2015 Mode, continue for 1 year, during which recurrent exerbation, is taken after 10d by top, and pain slows down, and continue to take after 1 course for the treatment of, pain Pain disappears, each course for the treatment of one month.
2nd, money so-and-so：38 years old, man was made a definite diagnosis with scapulohumeral periarthritis, cervical vertebra, using controlling that doctor trained in Western medicine, physiotherapy are combined in January, 2014 Treatment mode, continue for 2 years, during which recurrent exerbation, be taken by top after a course for the treatment of, pain slows down, and continue to take 1 treatment Cheng Hou, pain disappears, and does not recur again, each course for the treatment of one month.
3rd, Mr. Wang：52 years old, female was made a definite diagnosis in March, 2015 with cervical vertebra, the treatment side being combined using doctor trained in Western medicine, physiotherapy Formula, continue for three months, during which recurrent exerbation, is taken by top after 10d, pain slows down, and continue to take after 1 course for the treatment of, pain Pain disappears, and does not recur again, each course for the treatment of one month.
4th, Mr. Li：48 years old, man was made a definite diagnosis with cervical vertebra, lumbar vertebrae in October, 2014, is combined using doctor trained in Western medicine, physiotherapy Therapeutic modality, continue for 8 months, during which recurrent exerbation, taken by top after a course for the treatment of, pain slows down, continue to take 2 After the individual course for the treatment of, pain disappears, and does not recur again, each course for the treatment of one month.
So far, patient body is healthy always for the present inventor's follow-up, and the incidence of disease is persistently reduced, and the pain fallen ill every time is gradually Decline, wherein, improvement rate is more than 80%.

Claims (9)

1. a kind of composition for treating neck, shoulder, lumbar disc disease, it is characterised in that including following raw material by weight：Levisticum 10~20, bark of ash 10~15, geranium wilfordii 8~12, frankincense 8~12, myrrh 8~12, the root of Dahurain angelica 10~20, monkshood 8~12, Herba Siegesbeckiae 10~20, honeysuckle 15~25, river ox paint 10~20, Ligusticum wallichii 25~35, erythrina bark 10~20, safflower 10~15, radix scutellariae 8~ 12nd, notopterygium root 15~25, Radix Aconiti Kusnezoffii 4~8, the raw Radix Astragali 45~55, schizonepeta 10~20.
2. as claimed in claim 1 treatment neck, shoulder, the composition of lumbar disc disease, it is characterised in that including it is following by weight The raw material of meter：Levisticum 15, bark of ash 13, geranium wilfordii 10, frankincense 10, myrrh 10, the root of Dahurain angelica 15, monkshood 10, Herba Siegesbeckiae 15, honeysuckle 20th, river ox paint 15, Ligusticum wallichii 30, erythrina bark 15, safflower 13, radix scutellariae 10, notopterygium root 20, Radix Aconiti Kusnezoffii 6, the raw Radix Astragali 50, schizonepeta 15.
3. treating neck, shoulder, the composition of lumbar disc disease as claimed in claim 1, it is characterised in that described composition, it is Oral formulations, preferably steep in wine, oral liquid, tablet, pill or capsule.
4. neck, shoulder, the preparation method of lumbar disc disease composition are treated as claimed in claim 3, it is characterised in that described bubble Wine, is after raw material is cleaned, to be sealed and soaked with white wine, 15d is at least soaked in summer, 30d is at least soaked in the winter time.
5. neck, shoulder, the preparation method of lumbar disc disease composition are treated as claimed in claim 4, it is characterised in that described is white Wine, is the white wine brewed with single grain, its alcoholic strength >=50%vol.
6. neck, shoulder, the preparation method of lumbar disc disease composition are treated as claimed in claim 3, it is characterised in that described mouth Liquid is taken, is after raw material is weighed, to clean, add water infusion three times, each 30min, three filtrates is mixed, add mixing filtrate total The ethanol of 5 times of amounts of quality, is reclaimed after ethanol, adds monose, the sugar content of regulation residual solution is 20~30%, packaging.
7. neck, shoulder, the preparation method of lumbar disc disease composition are treated as claimed in claim 3, it is characterised in that described piece Agent, is after raw material is weighed, to clean, crushes, add water to cook into the medicinal extract that water content is 12~15%, add the 18 of medicinal extract quality ~25% amylum pregelatinisatum, then infiltrated with 65% ethanol, 0.5% magnesium stearate for adding total amount is mixed, and passes through tabletting Machine is tabletted, obtains tablet.
8. neck, shoulder, the preparation method of lumbar disc disease composition are treated as claimed in claim 3, it is characterised in that described ball Agent, is to weigh raw material, is cleaned, and is crushed, and adds 18~25% pregelatinized starch of total amount, then is infiltrated with 75% ethanol, Granulated by comminutor, particle is made, sieved, obtain pill.
9. neck, shoulder, the preparation method of lumbar disc disease composition are treated as claimed in claim 3, it is characterised in that described glue Wafer, is to weigh raw material, is cleaned, and is crushed, then with methylcellulose or alginates or polyvinyl alcohol or metagelatin system Standby capsulae vacuus is wrapped up, and is prepared into capsule.
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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107617098A (en) * 2017-10-29 2018-01-23 贵州松桃信仁苗药有限公司 One kind treats psoriasic composition
CN107617053A (en) * 2017-10-29 2018-01-23 贵州松桃信仁苗药有限公司 A kind of composition for treating hemorrhoid
CN107714891A (en) * 2017-10-29 2018-02-23 贵州松桃信仁苗药有限公司 A kind of composition for treating osteoproliferation and disc herniation
CN107714871A (en) * 2017-08-22 2018-02-23 贵州布医坊民族特色用品有限公司 A kind of composition for treating protrusion of lumber intervertebral disc

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Publication number Priority date Publication date Assignee Title
CN101045141A (en) * 2007-04-27 2007-10-03 雷雨田 Medicine for treating neck, shoulder, carina, lumbar vertebra disease

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101045141A (en) * 2007-04-27 2007-10-03 雷雨田 Medicine for treating neck, shoulder, carina, lumbar vertebra disease

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107714871A (en) * 2017-08-22 2018-02-23 贵州布医坊民族特色用品有限公司 A kind of composition for treating protrusion of lumber intervertebral disc
CN107617098A (en) * 2017-10-29 2018-01-23 贵州松桃信仁苗药有限公司 One kind treats psoriasic composition
CN107617053A (en) * 2017-10-29 2018-01-23 贵州松桃信仁苗药有限公司 A kind of composition for treating hemorrhoid
CN107714891A (en) * 2017-10-29 2018-02-23 贵州松桃信仁苗药有限公司 A kind of composition for treating osteoproliferation and disc herniation

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Application publication date: 20170818