CN107617053A - A kind of composition for treating hemorrhoid - Google Patents
A kind of composition for treating hemorrhoid Download PDFInfo
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- CN107617053A CN107617053A CN201711028723.2A CN201711028723A CN107617053A CN 107617053 A CN107617053 A CN 107617053A CN 201711028723 A CN201711028723 A CN 201711028723A CN 107617053 A CN107617053 A CN 107617053A
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Abstract
The present invention relates to drug preparation technique field, more particularly to a kind of composition for treating hemorrhoid；Including following raw material by weight：Chinaroot greenbrier 25~35, air potato 25~35, the calyx and receptacle of a persimmon 25~35, paris polyphylla 20~28, rootstock jackinthepulpit tuber 20~28, rhizoma arisaematis 20~28, Herba Elephantopi scaberis 20~28, the bletilla striata 20~28, the numerous skin 10~16 of thorn；The composition of the present invention passes through with anti-inflammatory, it is promoting blood circulation and removing blood stasis, hemostasis, detumescence, the medicine of analgesic efficacy are combined, and can effectively reduce the occurrence frequency of hemorrhoids disease, reach the purpose for the treatment of hemorrhoids disease, suitable for various hemorrhoid, composition of the invention, its therapeutic effect is notable, clinical improvement rate is more than 93%, and patient is to drug absorption rate more than 98%.
Description
Technical field
The present invention relates to drug preparation technique field, more particularly to a kind of composition for treating hemorrhoid.
Background technology
Hemorrhoid (being commonly called as hemorrhoid) are a kind of common diseases positioned at anus area, and any age can all fall ill, but with the age
Increase, the incidence of disease gradually increases.In China, hemorrhoid are most common anorectal diseases.Hemorrhoid are anal orifice and rectal intestine bottom and anal mucosa
The soft venous groups of veniplex varicose occurs and is formed one or more a kind of chronic disease, be broadly divided into internal piles, outer
Hemorrhoid, mixed hemorrhoid.The incidence of disease of hemorrhoid is high, especially in mid-aged population, has a strong impact on normal live and work.At present
The method for the treatment of hemorrhoid is divided into operative treatment and non-operative treatment, and expenses of surgical treatment is high, post-operative recovery time length；No operation is controlled
As long as treatment is drug therapy, but existing medicine at present, it is mostly the pain for mitigating patient, effects a radical cure DeGrain, disable
Afterwards it is also possible that bounce-back.At present, using modus operandi, 1. thrombosed external hemorrhoid decollement is applicable more for treatment of the doctor trained in Western medicine for hemorrhoid
Pain is not alleviated or lump not diminution person after thrombosed external hemorrhoid expectant treatment.2. Milligan-Morgan is Milligan-Morgan methods.③
Classical art formula on whitehead operation (Whitehead arts) textbook, is easily caused the stricture of anus, seldom application clinical at present.④PPH
Rectal mucosa ring cutting stitching art in operation anastomat hemorrhoid.Created by Italian Longo doctor, 1998 start to promote, main suitable
For type III-IV degree mixed hemorrhoid, the annular hemorrhoid of prolapsing, and the II degree internal piles that part bleeding is serious.The machine of PPH treatment prolapsus hemorrhoid
Reason：2~3 centimetres of mucous membranes of circular resection lower rectum and sub-mucosal tissues, recover normal anatomical structures, i.e. anus pad return；Mucous membrane
The excision of undertissue, blood supply of the superior hemorrhoidal artery to hemorrhoid area is blocked, made postoperative hemorrhoid body atrophy.PPH operations are cut with traditional hemorrhoid
Except art is compared, operating time is short, postoperative pain is light, recovery is fast, few intercurrent disease, but the price of apparatus is costly, and drug therapy
Containing the medicine of antibiotic using some more, harm to the human body is larger, and because tcm therapy has Small side effects, anti-recurrence rate
Effect is good, can stablize the state of an illness, indiffusible feature so that and it has obtained quick application and popularization in hemorrhoids disease field, but
It is that, because the traditional Chinese medical science of the prior art formula is unreasonable, material composition is incorrect, causes the therapeutic effect of current hemorrhoids disease not
Significantly, cure rate is relatively low.There is the Chinese medicine preparation of research treatment hemorrhoids disease the country at present, and achieves certain effect, such as Shen
Please number CN201610638193.2 invention《A kind of Chinese medicine composition for treating hemorrhoid》Disclose a kind of Chinese medicine for treating hemorrhoid
Composition, belong to the hemorrhoid field of Chinese medicines, be made up of pseudo-ginseng, Poria cocos therefore son, rhizoma alismatis, hairyvein agrimony and liquor made from sorghum；Such as application number
CN201610046995.4 invention《Treat the pharmaceutical composition of hemorrhoid》Disclose a kind of pharmaceutical composition for treating hemorrhoid and
Its preparation method, pharmaceutical composition of the present invention be with creeping oxalis, RADIX SANGUISORBA, blackberry lily, betel nut, orange peel, lepidium seed, Divine Comedy, realgar,
Scorpio is bulk drug, and proportioning forms, and routinely various formulations can be made by preparation process, treatment hemorrhoid are evident in efficacy.But due to
Traditional Chinese medical science formula of the prior art is unreasonable, and material composition is incorrect, causes the therapeutic effect of current hemorrhoids disease not notable, good
Rate of rotation is relatively low.
The content of the invention
The present invention is in order to solve the above technical problems, provide a kind of composition for treating hemorrhoid.
Realized particular by following technical scheme：
A kind of composition for treating hemorrhoid, including following raw material by weight：Chinaroot greenbrier 25~35, air potato 25~35,
The calyx and receptacle of a persimmon 25~35, paris polyphylla 20~28, rootstock jackinthepulpit tuber 20~28, rhizoma arisaematis 20~28, Herba Elephantopi scaberis 20~28, the bletilla striata 20~
28th, numerous skin 10~16 is pierced.
Including following raw material by weight：Chinaroot greenbrier 30, air potato 30, the calyx and receptacle of a persimmon 30, paris polyphylla 24, rootstock jackinthepulpit tuber 24,
Rhizoma arisaematis 24, Herba Elephantopi scaberis 24, the bletilla striata 24, the numerous skin 12 of thorn.
Described composition, for agent of steeping in wine, oral solutions, pill, paste, lotion or suppository.
Described agent of steeping in wine, be after raw material is cleaned, immersion sealed with alcoholic strength >=50%vol white wine, summer extremely
15d is soaked less, at least soaks 30d in the winter time.
Described oral solutions, it is after raw material is weighed, cleans, crush, add the water of 3~4 times of the crushed material quality,
40~50min of infusion is heated, the ethanol of 10 times of amounts of crushed material quality is added, is ultrasonically treated under 45~55KHz frequency
1~2h is stood after 12~18min, ethanol is reclaimed, heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion twice, often
Secondary 30~40min, filtrate three times is mixed to be concentrated into mixes the 1/2 of filtrate volume, adjust the sugar content of concentrate for 20~
30%, packaging.
Described pill, it is to weigh raw material, cleans, crushes, add 18~22% pregelatinized starch of total amount, then use
75% ethanol infiltration, is granulated by comminutor, particle is made, sieved, obtain pill.
Described paste, it is after raw material is weighed, cleans, crush, adds the water of 1~2 times of the crushed material quality, heating
30~40min of infusion, the ethanol of 5 times of amounts of the crushed material quality are added, it is ultrasonically treated 12 under 45~55KHz frequency~
1~2h is stood after 18min, ethanol is reclaimed, heels is continued to heat, infusion obtains the medicinal extract that water content is 15~20%, then adds
Enter 35~40% vaseline of medicinal extract quality, mix, cooling.
Described lotion, it is after raw material is weighed, cleans, crush, adds the water of 2~3 times of the crushed material quality, heating
40~50min of infusion, the ethanol of 5 times of amounts of the crushed material quality are added, it is ultrasonically treated 12 under 45~55KHz frequency~
After 18min stand 1~2h, reclaim ethanol, heels is filtered, obtains filtrate, is being concentrated into the 1/2 of filtrate volume, by concentrate,
The hydrogen peroxide that alcohol that concentration is 30%, concentration are 1~2% is by 1~2:0.18~0.22:0.24~0.28 mass ratio mixing
It is made.
Described suppository, it is after raw material is weighed, cleans, the boric acid with the 15~25% of raw material total amount, raw material total amount
20~30% glucose mixing, is reconciled into the mixture with glycerine standby after pasty state, and glycerin gelatine heating water bath is melted
After change, pastel is added, mixed thoroughly, pours into and has been coated with the rectal suppository film of lubricant, 15 are made altogether, cooling, it is unnecessary to prune
Bolt block, Qi Mo, take out, pack and produce.
In summary, the beneficial effects of the present invention are：The composition of the present invention is promoting blood circulation and removing blood stasis by with anti-inflammatory, only
Blood, detumescence, the medicine of analgesic efficacy are combined, can effectively reduce the occurrence frequency of hemorrhoids disease, reach treatment hemorrhoids disease
Purpose, suitable for various hemorrhoid, composition of the invention, its therapeutic effect is notable, and clinical improvement rate is more than 93%, patient
To drug absorption rate more than 98%, while the pain brought using doctor trained in Western medicine and operation to patient is avoided, made after treatment without pair
With Chinese medicine material uneasy to recur and easy to operate while selected is readily available, and cheap.
Embodiment
The embodiment of the present invention is described in further detail below, but the invention is not limited in these realities
Mode is applied, any improvement or replacement on the present embodiment essence spirit, it is claimed to still fall within the claims in the present invention
Scope.
Embodiment 1
A kind of composition for treating hemorrhoid, including following raw material by weight：Chinaroot greenbrier 25kg, air potato 25kg, the calyx and receptacle of a persimmon
25kg, paris polyphylla 20kg, rootstock jackinthepulpit tuber 20kg, rhizoma arisaematis 20kg, Herba Elephantopi scaberis 20kg, bletilla striata 20kg, the numerous skin 10kg of thorn.
The composition of the treatment hemorrhoid, its preparation method are the white wine for being 50%vol with alcoholic strength after raw material is cleaned
Sealing immersion, 15d is at least soaked in summer, at least soaks 30d in the winter time.
Application method：The daily morning and evening takes once respectively, every time 30~40ml.
Embodiment 2
A kind of composition for treating hemorrhoid, including following raw material by weight：Chinaroot greenbrier 35kg, air potato 35kg, the calyx and receptacle of a persimmon
35kg, paris polyphylla 28kg, rootstock jackinthepulpit tuber 28kg, rhizoma arisaematis 28kg, Herba Elephantopi scaberis 28kg, bletilla striata 28kg, the numerous skin 16kg of thorn.
The composition of the treatment hemorrhoid, its preparation method are after raw material is weighed, and clean, crush, add the crushing
Expect the water of 3~4 times of quality, heat infusion 40min, the ethanol of 10 times of amounts of crushed material quality is added, under 45KHz frequency
1~2h is stood after being ultrasonically treated 12min, ethanol is reclaimed, heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion two
It is secondary, each 30min, filtrate three times is mixed and is concentrated into the 1/2 of mixing filtrate volume, the sugar content for adjusting concentrate is 20%,
Packaging.
Application method：Take respectively once in the morning, afternoon and evening daily, every time 60~70ml.
Embodiment 3
A kind of composition for treating hemorrhoid, including following raw material by weight：Chinaroot greenbrier 30kg, air potato 30kg, the calyx and receptacle of a persimmon
30kg, paris polyphylla 24kg, rootstock jackinthepulpit tuber 24kg, rhizoma arisaematis 24kg, Herba Elephantopi scaberis 24kg, bletilla striata 24kg, the numerous skin 12kg of thorn.
The composition of the treatment hemorrhoid, its preparation method is to weigh raw material, is cleaned, and crushes, adds the 20% of total amount
Pregelatinized starch, then with 75% ethanol infiltrate, be granulated by comminutor, particle be made, sieve, obtain pill.
Application method：Take respectively once in the morning, afternoon and evening daily, 1~2 every time.
Embodiment 4
A kind of composition for treating hemorrhoid, including following raw material by weight：Chinaroot greenbrier 25kg, air potato 35kg, the calyx and receptacle of a persimmon
25kg, paris polyphylla 28kg, rootstock jackinthepulpit tuber 20kg, rhizoma arisaematis 28kg, Herba Elephantopi scaberis 20kg, bletilla striata 28kg, the numerous skin 10kg of thorn.
The composition of the treatment hemorrhoid, its preparation method are after raw material is weighed, and clean, crush, add the crushing
Expect the water of 1~2 times of quality, heat infusion 40min, the ethanol of 5 times of amounts of crushed material quality is added, under 45KHz frequency
1~2h is stood after being ultrasonically treated 18min, ethanol is reclaimed, heels is continued to heat, infusion obtains the medicinal extract that water content is 15%,
40% vaseline of medicinal extract quality is added, is mixed, paste is made in cooling.
Application method：Use once every night, every time in use, by paste application around hemorrhoid affected part, morning next day supernatant
Wash off.
Embodiment 5
A kind of composition for treating hemorrhoid, including following raw material by weight：Chinaroot greenbrier 35kg, air potato 25kg, the calyx and receptacle of a persimmon
35kg, paris polyphylla 20kg, rootstock jackinthepulpit tuber 28kg, rhizoma arisaematis 20kg, Herba Elephantopi scaberis 28kg, bletilla striata 20kg, the numerous skin 16kg of thorn.
The composition of the treatment hemorrhoid, its preparation method are after raw material is weighed, and clean, crush, add the crushing
Expect the water of 2~3 times of quality, heat infusion 50min, the ethanol of 5 times of amounts of crushed material quality is added, under 45KHz frequency
1~2h is stood after being ultrasonically treated 18min, ethanol is reclaimed, heels is filtered, obtains filtrate, is being concentrated into the 1/2 of filtrate volume,
By alcohol that concentrate, concentration are 30%, concentration be 2% hydrogen peroxide by 2:0.18:0.28 mass ratio is mixed to prepare lotion.
Application method：It is daily to clean 1~2 time, every time in use, lotion is diluted with water into the solution that content is 50%,
Hemorrhoid affected part is cleaned, natural air drying, is sure not to be washed out with clear water.
Embodiment 6
A kind of composition for treating hemorrhoid, including following raw material by weight：Chinaroot greenbrier 30kg, air potato 25kg, the calyx and receptacle of a persimmon
35kg, paris polyphylla 25kg, rootstock jackinthepulpit tuber 20kg, rhizoma arisaematis 28kg, Herba Elephantopi scaberis 24kg, bletilla striata 28kg, the numerous skin 10kg of thorn.
The composition of the treatment hemorrhoid, its preparation method are after raw material is weighed, and are cleaned, with the 25% of raw material total amount
Boric acid, the 20% glucose mixing of raw material total amount, the mixture reconciled into glycerine it is standby after pasty state, by glycerin gelatine
After heating water bath fusing, pastel is added, mixed thoroughly, pours into and has been coated with the rectal suppository film of lubricant, is made 15 altogether, it is cold
But, unnecessary bolt block is pruned, Qi Mo, takes out, packs and produce suppository.
Application method：Used once every 2d, every time in use, a suppository is filled in anus.
Experimental example
1st, it is some to randomly select the patient of the hemorrhoids disease of similar symptom, is randomly divided into 6 groups, embodiment 1~6 is respectively adopted
The composition of preparation is treated, and the applicant tracks follow-up, counts treatment of the patient to medicine, as a result as shown in table 1：
Table 1
| Project | Improvement rate % | Drug absorption rate % |
| Embodiment 1 | 93.5 | 98.6 |
| Embodiment 2 | 95.5 | 98.9 |
| Embodiment 3 | 94.8 | 98.3 |
| Embodiment 4 | 93.8 | 98.6 |
| Embodiment 5 | 94.7 | 98.8 |
| Embodiment 6 | 95.6 | 98.8 |
2nd, efficacy test example：The present invention takes safety, easy to operate, evident in efficacy, efficient high, and is clinical data institute
Prove, the relevant clinical data of the present invention is as follows：
1st, Song：45 years old, man, make a definite diagnosis in November, 2015 with the internal piles second phase, using the therapeutic modality of doctor trained in Western medicine, continue
1 year, during which recurrent exerbation, by top using average 5d after, pain slows down, continue after taking 1 course for the treatment of, pain disappears
Lose, each course for the treatment of 15d.
2nd, money so-and-so：38 years old, man, make a definite diagnosis in January, 2014 with making a definite diagnosis with the phase of internal piles three, using the treatment side of doctor trained in Western medicine
Formula, 2 years are continue for, during which recurrent exerbation, after using a course for the treatment of by top, pain slows down, and continues after taking 1 course for the treatment of,
Pain disappears, and does not recur again, each course for the treatment of 15d.
3rd, Mr. Wang：52 years old, female was made a definite diagnosis in March, 2015 with thrombosed external hemorrhoid, is controlled using what doctor trained in Western medicine, physiotherapy were combined
Treatment mode, three months are continue for, during which recurrent exerbation, after taking two courses for the treatment of by top, pain slows down, and continues to take 1
After the course for the treatment of, pain disappears, and does not recur again, each course for the treatment of 15d.
4th, Mr. Li：48 years old, man, make a definite diagnosis in October, 2014 with inflammatory external hemorrhoid, be combined using doctor trained in Western medicine, physiotherapy
Therapeutic modality, 8 months are continue for, during which recurrent exerbation, after taking a course for the treatment of by top, pain slows down, and continues to take 2
After the course for the treatment of, pain disappears, and does not recur again, each course for the treatment of 15d.
So far, patient body is healthy always for the present inventor's follow-up, and the incidence of disease persistently reduces, wherein, improvement rate 98% with
On.
Claims (9)
1. a kind of composition for treating hemorrhoid, it is characterised in that including following raw material by weight：Chinaroot greenbrier 25~35, Huang
Only 25~35, the calyx and receptacle of a persimmon 25~35, paris polyphylla 20~28, rootstock jackinthepulpit tuber 20~28, rhizoma arisaematis 20~28, Herba Elephantopi scaberis 20~28,
The bletilla striata 20~28, the numerous skin 10~16 of thorn.
2. the composition for the treatment of hemorrhoid as claimed in claim 1, it is characterised in that including following raw material by weight：
Chinaroot greenbrier 30, air potato 30, the calyx and receptacle of a persimmon 30, paris polyphylla 24, rootstock jackinthepulpit tuber 24, rhizoma arisaematis 24, Herba Elephantopi scaberis 24, the bletilla striata 24, the numerous skin 12 of thorn.
3. the composition for the treatment of hemorrhoid as claimed in claim 1, it is characterised in that described composition, for agent of steeping in wine, orally
Liquor, pill, paste, lotion or suppository.
4. the composition for the treatment of hemorrhoid as claimed in claim 3, it is characterised in that described agent of steeping in wine, is to clean raw material
Afterwards, immersion is sealed with alcoholic strength >=50%vol white wine, 15d is at least soaked in summer, at least soaks 30d in the winter time.
5. the composition for the treatment of hemorrhoid as claimed in claim 3, it is characterised in that described oral solutions, be to claim raw material
After taking, clean, crush, add the water of 3~4 times of the crushed material quality, heat 40~50min of infusion, add the crushed material
The ethanol of 10 times of amounts of quality, 1~2h is stood after 12~18min is ultrasonically treated under 45~55KHz frequency, reclaims ethanol, will
Heels is filtered, and obtains filtrate, then filter residue repetition is added into water infusion twice, every time 30~40min, filtrate mixing will be concentrated into three times
The 1/2 of filtrate volume is mixed, the sugar content for adjusting concentrate is 20~30%, packaging.
6. the composition for the treatment of hemorrhoid as claimed in claim 3, it is characterised in that described pill, be to weigh raw material, wash
Only, crush, add 18~22% pregelatinized starch of total amount, then infiltrated with 75% ethanol, be granulated, be made by comminutor
Particle, sieving, obtains pill.
7. the composition for the treatment of hemorrhoid as claimed in claim 3, it is characterised in that described paste, be after raw material is weighed,
Clean, crush, add the water of 1~2 times of the crushed material quality, heat 30~40min of infusion, add the crushed material quality 5
The ethanol of amount again, 1~2h is stood after 12~18min is ultrasonically treated under 45~55KHz frequency, ethanol is reclaimed, by heels
Continuing to heat, infusion obtains the medicinal extract that water content is 15~20%, adds 35~40% vaseline of medicinal extract quality, mixes,
Cooling.
8. the composition for the treatment of hemorrhoid as claimed in claim 3, it is characterised in that described lotion, be after raw material is weighed,
Clean, crush, add the water of 2~3 times of the crushed material quality, heat 40~50min of infusion, add the crushed material quality 5
The ethanol of amount again, 1~2h is stood after 12~18min is ultrasonically treated under 45~55KHz frequency, ethanol is reclaimed, by heels
Filtering, obtains filtrate, is being concentrated into the 1/2 of filtrate volume, by alcohol that concentrate, concentration are 30%, concentration be 1~2% it is double
Oxygen water presses 1~2:0.18~0.22:0.24~0.28 mass ratio is mixed to prepare.
9. the composition for the treatment of hemorrhoid as claimed in claim 3, it is characterised in that described suppository, be after raw material is weighed,
Clean, the boric acid with the 15~25% of raw material total amount, 20~30% glucose mixing of raw material total amount will be described mixed with glycerine
Compound reconciles into standby after pasty state, after glycerin gelatine heating water bath is melted, pastel is added, mixed thoroughly, pours into and has been coated with moistening
In the rectal suppository film of lubrication prescription, 15 are made altogether, cooling, prunes unnecessary bolt block, Qi Mo, takes out, pack and produce.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711028723.2A CN107617053A (en) | 2017-10-29 | 2017-10-29 | A kind of composition for treating hemorrhoid |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201711028723.2A CN107617053A (en) | 2017-10-29 | 2017-10-29 | A kind of composition for treating hemorrhoid |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181444A (en) * | 2007-11-16 | 2008-05-21 | 刘海燕 | Multi-efficacy externally used drug as well as method for preparing immersion agent thereof |
| CN107050137A (en) * | 2017-03-29 | 2017-08-18 | 贵州银老太侗医药有限公司 | A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof |
-
2017
- 2017-10-29 CN CN201711028723.2A patent/CN107617053A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101181444A (en) * | 2007-11-16 | 2008-05-21 | 刘海燕 | Multi-efficacy externally used drug as well as method for preparing immersion agent thereof |
| CN107050137A (en) * | 2017-03-29 | 2017-08-18 | 贵州银老太侗医药有限公司 | A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof |
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Application publication date: 20180123 |