CN107714891A - A kind of composition for treating osteoproliferation and disc herniation - Google Patents

A kind of composition for treating osteoproliferation and disc herniation Download PDF

Info

Publication number
CN107714891A
CN107714891A CN201711042130.1A CN201711042130A CN107714891A CN 107714891 A CN107714891 A CN 107714891A CN 201711042130 A CN201711042130 A CN 201711042130A CN 107714891 A CN107714891 A CN 107714891A
Authority
CN
China
Prior art keywords
osteoproliferation
disc herniation
composition
treatment
radix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711042130.1A
Other languages
Chinese (zh)
Inventor
李�杰
郭宇
李思林
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guizhou Songtao Miao Medicine Co Ltd Nobuhito
Original Assignee
Guizhou Songtao Miao Medicine Co Ltd Nobuhito
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guizhou Songtao Miao Medicine Co Ltd Nobuhito filed Critical Guizhou Songtao Miao Medicine Co Ltd Nobuhito
Priority to CN201711042130.1A priority Critical patent/CN107714891A/en
Publication of CN107714891A publication Critical patent/CN107714891A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/888Araceae (Arum family), e.g. caladium, calla lily or skunk cabbage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to drug preparation technique field, more particularly to a kind of composition for treating osteoproliferation and disc herniation;Including following raw material by weight:Tripterygium wilfordii 25~35, Radix Amydrii sinensis 25~35, Gotu Kola 25~35, catchweed bedstraw herb 25~35, fragrant spicebush bark or branchlet and leaf 25~35, aspidistra 25~35, balsamine 20~30, spinyleaf pricklyash root 20~30, alpine yallow herb 15~25, decumbent corydalis tuber 15~25, Radix Alangii 15~25, cat fur 10~20;The composition of the present invention is combined by the medicine with wind dispelling, dehumidifying, analgesia, dissolving stasis, analgesic efficacy, the sclerotin of hyperplasia can effectively be dissolved, prevent osteoproliferation, the connective tissue that interverbebral disc prominent (swollen) goes out can be cleared up, effectively reduce the occurrence frequency of osteoproliferation and disc herniation disease, reach the purpose for the treatment of osteoproliferation and disc herniation disease, suitable for various osteoproliferation and disc herniation disease.

Description

A kind of composition for treating osteoproliferation and disc herniation
Technical field
The present invention relates to drug preparation technique field, more particularly to a kind of combination for treating osteoproliferation and disc herniation Thing.
Background technology
Hyperostosis is mainly in above middle age.It is generally acknowledged that due to being had a delicate constitution after the middle age and retrogression;For a long time Stand or walk and be held in certain posture for a long time, due to the drawing of muscle or avulsion, bleeding, organization of hematoma, form thorn-like Or the osteoproliferation of lip sample;Spur to soft tissue produce it is mechanical stimulation and wound after soft tissue injury, bleeding, swelling and Cause, including cervical vertebrae hyperosteogeny, lumbar vertebrae hyperosteogeny, articulatio genus hyperosteogeny;The protrasion of the lumbar intervertebral disci is relatively conventional disease One of suffer from, lumber ertebral disc each several part (nucleus pulposus, fibrous ring and cartilage plate), especially nucleus pulposus are primarily due to, is had different degrees of After degenerative change, in the presence of external force factor, the Anular disruption of interverbebral disc, nucleus pulposus from rupture part it is prominent (or Abjection) in rear or intraspinal tube, cause adjacent spinal nerve root to be stimulated or oppressed, so as to produce flank pain, side lower limb A series of or clinical symptoms such as double lower limb numbness, pain.At present, treatment of the doctor trained in Western medicine for osteoproliferation and disc herniation is adopted more Medicine is based on antibiotic, hormone, anodyne, and physiotherapy is with partial insulation, physiotherapy, acupuncture, massage, though so contribute to fast Quick-recovery, slow down pain, its short run effect is fine, but can not remove root.Drug therapy is carried out for the more long patient of stadium, But prolonged administration of drugs can not only develop immunity to drugs, it is disorderly also to produce such as gastrointestinal function damage, osteoporosis, endocrine Disorderly, the adverse reaction such as nervous system disorders and cortin hyperfunction, and root can not be thoroughly removed, and use physiotherapy, then need to grow Time adheres to, it is impossible to interrupts, but is not easy to effect a radical cure, and because tcm therapy has Small side effects, anti-recurrence rate effect is good, can be steady Determine the state of an illness, indiffusible feature so that it has obtained quick application in osteoproliferation and disc herniation disease areas and pushed away Extensively, still, because the traditional Chinese medical science of the prior art formula is unreasonable, material composition is incorrect, causes current osteoproliferation and intervertebral The therapeutic effect that disk protrudes disease is not notable, and cure rate is relatively low.There are research treatment osteoproliferation and disc herniation in the country at present Chinese medicine preparation, and certain effect is achieved, such as application number CN201410349985.9 invention《A kind of medicine for treating hyperosteogeny》 A kind of medicine for treating hyperosteogeny is disclosed, the medicine for treating hyperosteogeny is made up of the medicinal material of following parts by weight:Chinese ephedra 30-33, cassia twig 10- 15th, root of fangji 20-25, rheum officinale 40-48, licorice 10, pawpaw 10-16, the capsule of weeping forsythia 10, radix ampelopsis 16, agalloch eaglewood 13-16, rattletop 16, bark of ash 10th, safflower 5, peach kernel 5-10, radix cyathulae 10-16, radix scutellariae 10, Radix Rhapontici seu Radix Echinopsis 10-15, Radix Angelicae Sinensis 10-15 and costus root 10-16;Such as application Number CN201310293008.7 invention《Treat the Chinese medicine preparation of disc herniation》Disclose a kind of disc herniation for the treatment of Chinese medicine preparation, it is characterized in that made of the raw material of following weight proportion:Leech 3-5 parts;Scorpio 8-10, dragon's blood 15-20, Chinese ephedra 8-10, earthworm 8-10, arisaema cum bile 3-5, teasel 15-20, peach kernel 15-20, Semen Strychni (processed) 5-8, Radix Angelicae Sinensis 15-20, Morinda officinalis 5- 8th, Common St.Paulswort Herb 5-8, rhizome of Maire Greenbrier 8-10, Stephania tetrandra 8-10, coix seed 12-25, ground bettle 4-7, cassia twig 8-10, catechu 8-10, Shen Ginger 8-10, bark of ash 15-20, rhizoma homalonemae 15-20, the extra large 8-10 in side, caulis trachelospermi 15-20, Sichuan troops 15-20.But due to prior art In the traditional Chinese medical science formula it is unreasonable, material composition is incorrect, causes the treatment at present for osteoproliferation and disc herniation disease Effect is not notable, and improvement rate is relatively low.
The content of the invention
The present invention is in order to solve the above technical problems, provide a kind of composition for treating osteoproliferation and disc herniation.
Realized particular by following technical scheme:
A kind of composition for treating osteoproliferation and disc herniation, including following raw material by weight:Tripterygium wilfordii 25~35, Radix Amydrii sinensis 25~35, Gotu Kola 25~35, catchweed bedstraw herb 25~35, fragrant spicebush bark or branchlet and leaf 25~35, aspidistra 25~35, phoenix Celestial being spends 20~30, spinyleaf pricklyash root 20~30, alpine yallow herb 15~25, decumbent corydalis tuber 15~25, Radix Alangii 15~25, cat fur 10~20.
Including following raw material by weight:Tripterygium wilfordii 30, Radix Amydrii sinensis 30, Gotu Kola 30, catchweed bedstraw herb 30, fragrant spicebush bark or branchlet and leaf 30th, aspidistra 30, balsamine 25, spinyleaf pricklyash root 25, alpine yallow herb 20, decumbent corydalis tuber 20, Radix Alangii 20, cat fur 15.
Described composition, for agent of steeping in wine, oral solutions, pill, paste.
Described agent of steeping in wine, be after raw material is cleaned, immersion sealed with alcoholic strength >=50%vol white wine, summer extremely 15d is soaked less, at least soaks 30d in the winter time.
Described oral solutions, it is after raw material is weighed, cleans, crush, add the water of 3~4 times of the crushed material quality, Infusion 40min is heated, adds the ethanol of 10 times of amounts of crushed material quality, it is quiet after supersound process 15min under 50KHz frequency 1~2h is put, ethanol is reclaimed, heels is filtered, obtains filtrate, then filter residue repetition is added into water infusion twice, each 30min, by three Secondary filtrate mixing, which is concentrated into, mixes the 1/2 of filtrate volume, and the sugar content for adjusting concentrate is 20%, packaging.
Described pill, it is to weigh raw material, cleans, crush, adds 20% pregelatinized starch of total amount, then with 75% Ethanol infiltration, be granulated by comminutor, particle be made, sieve, obtain pill.
Described paste, it is after raw material is weighed, cleans, crush, adds the water of 1~2 times of the crushed material quality, heating Infusion 30min, the ethanol of 5 times of amounts of the crushed material quality are added, be ultrasonically treated under 50KHz frequency after 12min and stand 1~ 2h, ethanol is reclaimed, heels continued to heat, infusion obtains the medicinal extract that water content is 20%, adds the 40% of medicinal extract quality Vaseline, mix, cooling.
In summary, the beneficial effects of the present invention are:The composition of the present invention by with wind dispelling, dehumidifying, ease pain, dispel The stasis of blood, the medicine of analgesic efficacy are combined, and can effectively be dissolved the sclerotin of hyperplasia, be prevented osteoproliferation, can clear up interverbebral disc and dash forward The connective tissue that (swollen) goes out, the occurrence frequency of osteoproliferation and disc herniation disease is effectively reduced, reaches treatment osteoproliferation With the purpose of disc herniation disease, suitable for various osteoproliferation and disc herniation disease, composition of the invention, it is controlled Therapeutic effect is notable, and more than 94%, patient more than 97%, while avoids using doctor trained in Western medicine clinical improvement rate to drug absorption rate The pain brought to patient, have no side effect after treatment, Chinese medicine material uneasy to recur and easy to operate while selected holds Easily obtain, and it is cheap.
Embodiment
The embodiment of the present invention is described in further detail below, but the invention is not limited in these realities Mode is applied, any improvement or replacement on the present embodiment essence spirit, it is claimed to still fall within the claims in the present invention Scope.
Embodiment 1
A kind of composition for treating osteoproliferation and disc herniation, including following raw material by weight:Tripterygium wilfordii 25kg, Radix Amydrii sinensis 25kg, Gotu Kola 25kg, catchweed bedstraw herb 25kg, fragrant spicebush bark or branchlet and leaf 25kg, aspidistra 25kg, balsamine 20kg, see blood Fly 20kg, alpine yallow herb 15kg, decumbent corydalis tuber 15kg, Radix Alangii 15kg, cat fur 10kg.
Described treatment osteoproliferation and the composition of disc herniation, its preparation method are after raw material is cleaned, to use wine The white wine sealing immersion that precision is 50%vol, 15d is at least soaked in summer, at least soaks 30d in the winter time, must steep in wine agent.
Application method:The daily morning and evening takes once respectively, every time 30~40ml.
Embodiment 2
A kind of composition for treating osteoproliferation and disc herniation, including following raw material by weight:Tripterygium wilfordii 35kg, Radix Amydrii sinensis 35kg, Gotu Kola 35kg, catchweed bedstraw herb 35kg, fragrant spicebush bark or branchlet and leaf 35kg, aspidistra 35kg, balsamine 30kg, see blood Fly 30kg, alpine yallow herb 25kg, decumbent corydalis tuber 25kg, Radix Alangii 25kg, cat fur 20kg.
Described treatment osteoproliferation and the composition of disc herniation, its preparation method are after raw material is weighed, and are cleaned, Crush, add the water of 3~4 times of the crushed material quality, heat infusion 40min, add the second of 10 times of amounts of crushed material quality Alcohol, 1~2h is stood after 15min is ultrasonically treated under 50KHz frequency, ethanol is reclaimed, heels is filtered, obtain filtrate, then will Filter residue is repeated to add water infusion twice, each 30min, and filtrate three times is mixed and is concentrated into the 1/2 of mixing filtrate volume, regulation concentration The sugar content of liquid is 20%, packs and produces oral solutions.
Application method:Take respectively once in the morning, afternoon and evening daily, every time 60~70ml.
Embodiment 3
A kind of composition for treating osteoproliferation and disc herniation, including following raw material by weight:Tripterygium wilfordii 30kg, Radix Amydrii sinensis 30kg, Gotu Kola 30kg, catchweed bedstraw herb 30kg, fragrant spicebush bark or branchlet and leaf 30kg, aspidistra 30kg, balsamine 25kg, see blood Fly 25kg, alpine yallow herb 20kg, decumbent corydalis tuber 20kg, Radix Alangii 20kg, cat fur 15kg.
Described treatment osteoproliferation and the composition of disc herniation, its preparation method are to weigh raw material, are cleaned, powder It is broken, 20% pregelatinized starch of total amount is added, then infiltrated with 75% ethanol, it is granulated by comminutor, particle, mistake is made Sieve, obtains pill.
Application method:Take respectively once in the morning, afternoon and evening daily, 1~2 every time.
Embodiment 4
A kind of composition for treating osteoproliferation and disc herniation, including following raw material by weight:Tripterygium wilfordii 25kg, Radix Amydrii sinensis 35kg, Gotu Kola 25kg, catchweed bedstraw herb 35kg, fragrant spicebush bark or branchlet and leaf 30kg, aspidistra 30kg, balsamine 20kg, see blood Fly 30kg, alpine yallow herb 20kg, decumbent corydalis tuber 20kg, Radix Alangii 15kg, cat fur 20kg.
Described treatment osteoproliferation and the composition of disc herniation, its preparation method are after raw material is weighed, and are cleaned, Crush, add the water of 1~2 times of the crushed material quality, heat infusion 30min, add the second of 5 times of amounts of crushed material quality Alcohol, 1~2h is stood after 12min is ultrasonically treated under 50KHz frequency, ethanol is reclaimed, heels is continued to heat, infusion must contain Water is 20% medicinal extract, adds 40% vaseline of medicinal extract quality, mixes, cools down and produce paste.
Application method:Use once every three days, every time in use, by paste application around affected part, immobilization with adhesive tape is Can.
1st, randomly select similar symptom osteoproliferation and disc herniation patient it is some, be randomly divided into 4 groups, adopt respectively The composition prepared with embodiment 1~4 is treated, and the applicant tracks follow-up, counts the improvement situation of patient and to medicine The absorbing state of thing, as a result as shown in table 1:
Table 1
Project Improvement rate % Drug absorption rate %
Embodiment 1 95.5 98.6
Embodiment 2 94.8 98.1
Embodiment 3 94.2 97.9
Embodiment 4 95.2 98.4
2nd, efficacy test example:The present invention takes safety, easy to operate, evident in efficacy, efficient high, and is clinical data institute Prove, the relevant clinical data of the present invention is as follows:
1st, Song:50 years old, man, made a definite diagnosis in November, 2015 concurrent with articulatio genus hyperosteogeny and protrusion of lumber intervertebral disc Disease, the therapeutic modality being combined using doctor trained in Western medicine, physiotherapy, 1 year is continue for, during which recurrent exerbation, after taking 10d by top, pain Sense slows down, and continues after taking 1 course for the treatment of, and pain disappears, each course for the treatment of one month.
2nd, Hu:55 years old, man, make a definite diagnosis in January, 2014 with lumbar vertebrae hyperosteogeny, be combined using doctor trained in Western medicine, physiotherapy Therapeutic modality, 2 years are continue for, during which recurrent exerbation, after taking a course for the treatment of by top, pain slows down, and continues to take 1 After the course for the treatment of, pain disappears, and does not recur again, each course for the treatment of one month.
3rd, Mr. Wang:58 years old, female was made a definite diagnosis in March, 2015 with cervical vertebra and lumbar vertebrae hyperosteogeny complication, using west The therapeutic modality that doctor, physiotherapy are combined, continue for three months, during which recurrent exerbation, and after taking 10d by top, pain slows down, Continue after taking 1 course for the treatment of, pain disappears, and does not recur again, each course for the treatment of one month.
So far, patient body is healthy always for the present inventor's follow-up, and the incidence of disease persistently reduces, and the pain fallen ill every time is gradually Decline, wherein, improvement rate is more than 98%.

Claims (7)

1. a kind of composition for treating osteoproliferation and disc herniation, it is characterised in that including following original by weight Material:Tripterygium wilfordii 25~35, Radix Amydrii sinensis 25~35, Gotu Kola 25~35, catchweed bedstraw herb 25~35, fragrant spicebush bark or branchlet and leaf 25~35, aspidistra 25~35, balsamine 20~30, spinyleaf pricklyash root 20~30, alpine yallow herb 15~25, decumbent corydalis tuber 15~25, Radix Alangii 15~25, cat skin Hair 10~20.
2. the composition for the treatment of osteoproliferation and disc herniation as claimed in claim 1, it is characterised in that including pressing below The raw material of parts by weight meter:Tripterygium wilfordii 30, Radix Amydrii sinensis 30, Gotu Kola 30, catchweed bedstraw herb 30, fragrant spicebush bark or branchlet and leaf 30, aspidistra 30, balsamine 25th, spinyleaf pricklyash root 25, alpine yallow herb 20, decumbent corydalis tuber 20, Radix Alangii 20, cat fur 15.
3. the composition for the treatment of osteoproliferation and disc herniation as claimed in claim 1, it is characterised in that described combination Thing, for agent of steeping in wine, oral solutions, pill, paste.
4. the composition for the treatment of osteoproliferation and disc herniation as claimed in claim 3, it is characterised in that described steeps in wine Agent, it is after raw material is cleaned, seals immersion with alcoholic strength >=50%vol white wine, 15d is at least soaked in summer, in the winter time extremely 30d is soaked less.
5. the composition for the treatment of osteoproliferation and disc herniation as claimed in claim 3, it is characterised in that described is oral Liquor, it is after raw material is weighed, cleans, crush, add the water of 3~4 times of the crushed material quality, heat infusion 40min, add The ethanol of 10 times of amounts of crushed material quality, stands 1~2h after 15min is ultrasonically treated under 50KHz frequency, reclaims ethanol, Heels is filtered, obtains filtrate, then by filter residue repeat plus water infusion twice, each 30min, will three times filtrate mix be concentrated into it is mixed With the 1/2 of filtrate volume, the sugar content for adjusting concentrate is 20%, packaging.
6. the composition for the treatment of osteoproliferation and disc herniation as claimed in claim 3, it is characterised in that described ball Agent, it is to weigh raw material, cleans, crush, add 20% pregelatinized starch of total amount, then infiltrated with 75% ethanol, is passed through Comminutor is granulated, and particle is made, and is sieved, is obtained pill.
7. the composition for the treatment of osteoproliferation and disc herniation as claimed in claim 3, it is characterised in that described cream Agent, it is after raw material is weighed, cleans, crush, add the water of 1~2 times of the crushed material quality, heat infusion 30min, add institute The ethanol of 5 times of amounts of crushed material quality is stated, 1~2h is stood after 12min is ultrasonically treated under 50KHz frequency, reclaims ethanol, will be residual Clout continues to heat, and infusion obtains the medicinal extract that water content is 20%, adds 40% vaseline of medicinal extract quality, mixes, cooling .
CN201711042130.1A 2017-10-29 2017-10-29 A kind of composition for treating osteoproliferation and disc herniation Pending CN107714891A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711042130.1A CN107714891A (en) 2017-10-29 2017-10-29 A kind of composition for treating osteoproliferation and disc herniation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711042130.1A CN107714891A (en) 2017-10-29 2017-10-29 A kind of composition for treating osteoproliferation and disc herniation

Publications (1)

Publication Number Publication Date
CN107714891A true CN107714891A (en) 2018-02-23

Family

ID=61202389

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711042130.1A Pending CN107714891A (en) 2017-10-29 2017-10-29 A kind of composition for treating osteoproliferation and disc herniation

Country Status (1)

Country Link
CN (1) CN107714891A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050137A (en) * 2017-03-29 2017-08-18 贵州银老太侗医药有限公司 A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050137A (en) * 2017-03-29 2017-08-18 贵州银老太侗医药有限公司 A kind of composition for treating neck, shoulder, lumbar disc disease and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
韩仲成: "《随印会河待诊记》", 31 August 2012, 中国中医药出版社 *

Similar Documents

Publication Publication Date Title
CN102488869B (en) Traditional Chinese medicinal external-use liniment for muscle and bone ache
CN100423761C (en) Chinese medicinal preparation for treating fracture, traumatic injury
CN1824009B (en) Multipurpose medicinal composition capable of oral administration and external use
CN102552608B (en) Medicine composition used for treating fracture and bone injury, preparation method thereof, and purpose thereof
CN107007714A (en) It is a kind of that there is the exterior-applied medical wine for promoting poroma nucleus formation
CN103784550B (en) For Chinese medicine composition and the preparation thereof of swelling and pain relieving
CN104706782A (en) External tincture for treating bone poliomyelitis and preparation method of external tincture
CN107050138A (en) Pharmaceutical composition and its preparation and paste preparation method for treating osteoproliferation
CN107714891A (en) A kind of composition for treating osteoproliferation and disc herniation
CN106511905A (en) Traditional Chinese medicine preparation used for curing cervical spondylosis and preparation method thereof
CN103585294B (en) A kind of for plaster treating hyperosteogeny and preparation method thereof
CN106177002A (en) A kind of medicated powder medicated wine complex treating bone matrix hyperplasia
CN101708292A (en) Chinese medicament for treating rheumatic and rheumatoid diseases
CN109908246A (en) The external application Chinese medicine formula for treating lumbar pain orthopaedic disease
CN103191342B (en) Method for preparing diaphyseal aclasis nursing substance
CN117357608B (en) External application medicine for treating traumatic injury and fracture and tendon injury
CN103191343B (en) Pharmaceutical composition for treating diaphyseal aclasis
CN108355092A (en) Treat the cream of activating blood and relaxing tendons of rheumatic pain of neck, shoulder, waist and leg
CN107617098A (en) One kind treats psoriasic composition
CN108079195A (en) Treat the Chinese medicine composition of orthopaedic disease
CN115227765B (en) Preparation and application of uterus warming three-volt patch for treating dysmenorrhea
CN102178845B (en) Plaster for treating spur and preparation method thereof
CN107260828A (en) Pharmaceutical composition for treating closed soft tissue injury and injured bones and muscles
CN106692821A (en) Traditional Chinese medicine preparation for treating neurosurgical postoperative headache
CN110141643A (en) Treat prolapse of lumbar intervertebral disc, the anaesthetic composition of rheumatic arthritis and its application

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication

Application publication date: 20180223

RJ01 Rejection of invention patent application after publication