CN107260828A - Pharmaceutical composition for treating closed soft tissue injury and injured bones and muscles - Google Patents
Pharmaceutical composition for treating closed soft tissue injury and injured bones and muscles Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/238—Saposhnikovia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses a kind of pharmaceutical composition for being used to treat closed soft tissue injury and injured bones and muscles, belong to technical field of pharmaceuticals, be made up of following components in parts by weight：Radix Angelicae Sinensis：20 30 parts, Ligusticum wallichii：It is 20 30 parts, windproof：20 30 parts, peach kernel：10 15 parts, safflower：10 15 parts, the bark of eucommia：10 15 parts, teasel root：10 15 parts, sargentodoxa cuneata：10 15 parts, aconiti preparata,radix：28 parts, wild aconite root：28 parts；Raw material of the present invention is easy to get, and method is easy to grasp, and uses external preparation, and safe and reliable, Clinical practice has no obvious toxic-side effects in three months；For the treatment of closed soft tissue injury and injured bones and muscles, determined curative effect.
Description
Technical field
It is more particularly to a kind of to be used to treat closed soft tissue injury and injured bones and muscles the present invention relates to technical field of pharmaceuticals
Pharmaceutical composition.
Background technology
Closed soft tissue injury refers to that local skin or mucous membrane are complete, and no breach is communicated with the external world, bleeding during damage
Accumulate in tissue, be one kind of soft tissue injury.Acted on by blunt forces, muscle fiercely shrinks, joint motion surmounts normal range (NR)
Or strain etc. cause.
Closed soft tissue injury and injured bones and muscles be belong to the traditional Chinese medical science it is sick and wounded in " injury of the tissues " category, human body fallen
After the injuries such as external force and strain such as servant, pendant fall, hit, the sudden strain of a muscle, pressure rolling, cause local damage, injury is ached
The pathological change such as bitterly, swelling, functional activity be limited.Its interpretation of the cause, onset and process of an illness is impaired for tendon and vessel blood network, is deposited outside the excessive arteries and veins of blood in institute outside flesh side film
Cause.
The injury of the tissues can cause the malfunction of qi and blood, internal organs, channels and collaterals, cause general reaction.The injury of the tissues must the injury of the bone, skin and flesh muscles and bones
Damage, causes channels and collaterals to block, qi and blood stagnation or extravasated blood, evil poison are fromed superficies to interior and causes internal organs to get along well.Blood stored in the liver cage bar, liver blood fills
It is full of, muscle, which is obtained, supports, deficiency of liver-blood, exception will occur for the function of muscle；Kidney storing essence, the raw marrow of essence, marrow nourishing bone, so the growth of bone,
Development, reparation, are both needed to rely on the nourishing and promotion of kidney vital essence.Therefore, in order to promote muscle symphysis, it is necessary to take good care of liver
Kidney.
As described above, the drug therapy for closed soft tissue injury is treated at present, doctor trained in Western medicine is typically using non-steroid anti-
Scorching medicine (NSAIDs), the topical application of glucocorticoid and now new Selective COX-2 inhibitor, damage soft tissue
The treatment of the caused pain symptom of wound has significant curative effect, but many adverse drug reactions hinder clinical practice into it again
Factor, the cardiovascular event of such as Vioxx and valdecoxib remove city, and all these current Western medicine drug therapies of prompting are still not
The pain therapy of closed soft tissue injury and injured bones and muscles can be used for as a kind of safe method.
So, the treatment for closed soft tissue injury is simple there is provided a kind of component, and component is cheap and easily-available, and curative effect is true
Cut, the medicine that toxic side effect is small turns into a kind of issue to be resolved of those skilled in the art.
The content of the invention
The goal of the invention of the present invention is：There is provided a kind of new is used to treating closed soft tissue injury and injured bones and muscles
Pharmaceutical composition, to solve the above problems.
The technical solution adopted by the present invention is such：It is a kind of to be used to treat closed soft tissue injury and injured bones and muscles
Pharmaceutical composition, is made up of following components in parts by weight：
Radix Angelicae Sinensis：20-30 parts, Ligusticum wallichii：It is 20-30 parts, windproof：20-30 parts, peach kernel：10-15 parts, safflower：10-15 parts, the bark of eucommia：10-
15 parts, teasel root：10-15 parts, sargentodoxa cuneata：10-15 parts, aconiti preparata,radix：2-8 parts, wild aconite root：2-8 parts.
The present inventor is drawn by many experiments：Between said components, using suitable ratio, mutually collaboration,
Can be with promoting blood circulation, swelling and pain relieving, be particularly suitable for use in closed soft tissue injury and injured bones and muscles, symptoms include partial gall, pressing
Very pain person, its determined curative effect, toxic side effect is small, uneasy to recur.
Wherein, Radix Angelicae Sinensis, is umbelliferae angelica（Angelica sinensis(Oliv.) Diels）Dry root,
Major function is replenishing and activating blood, and menstruction regulating and pain relieving relaxes bowel.For blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, closed dysmenorrhea,
Asthenia cold abdominalgia, arthralgia pain due to rheumatism, injury from falling down, ulcer sores, dry constipation of intestines；
Ligusticum wallichii, samphire Ligusticum wallichii（Ligusticum chuanxiongHort.）Dry rhizome, it is warm-natured pungent, Return liver,
Courage, pericardium channel, blood-activating and qi-promoting, wind-expelling pain-stopping.For chest impediment and cardialgia, chest side of body shouting pain, tumbling and swelling, irregular menstruation, closed dysmenorrhea,
Disorder lump in the abdomen is suffered from abdominal pain, headache, arthralgia pain due to rheumatism；
It is windproof, it is umbelliferae Saposhnikovia divaricata（Saposhnikovia divaricate(Turcz.)Schischk.）Drying
Root, slightly warm in nature is pungent, sweet, returns bladder, liver, the spleen channel, expels pathogenic wind from the body surface, expel endogenous wind to relieve convulsion, only convulsion.For cold headache, rheumatism numbness
Pain , Feng Shen itch, lockjaw；
Peach kernel, is rosaceous plant peach（Prunus persica(L.)Batsch）Or mountain peach（Prunus davi diana
(Carr.) Franch.）Dry mature seed, mild-natured, bitter, sweet, the thoughts of returning home, liver, large intestine channel, promoting blood circulation relax bowel,
It is relieving cough and asthma, for closed dysmenorrhea , abdominal lump of mass in abdomen, lung carbuncle acute appendicitis, injury from falling down, dry constipation of intestines, cough and asthma；
Safflower, is feverfew safflower（Carthamus tinctoriusL.）Dry flower, property is pungent, temperature；The thoughts of returning home, Liver Channel；It is living
Blood stimulates the menstrual flow, blood stasis removing analgesic.For Amenorrhea, dysmenorrhoea, lochia , abdominal lump of mass in abdomen, chest impediment and cardialgia, stasis of blood, chest side of body is twinged, fallen
Damage is flutterred, girdle ulcer swells and ache
The bark of eucommia, is the Eucommiaceae plant bark of eucommia（Eucommia ulmoidesOliv.）Dry bark, nature and flavor are sweet, temperature, Return liver,
Kidney channel, with filling liver kidney, strengthening the bones and muscles, antiabortive effect, for kidney deficiency and liver, soreness of waist and knee joint, muscles and bones is powerless, has a dizzy spell, pregnant
It is pregnent leakage blood, the treatment of the illness such as fetal irritability；
Teasel root, is Dipsacaceae plant teasel（Dipsacus asperWall.ex Henry）Dry root, slightly warm in nature, taste
It is bitter, pungent；Return liver and kidney channel；There are filling liver kidney, strengthening the bones and muscles, continuous injured, only uterine bleeding, available for treatment kidney deficiency and liver, waist and knee acid
The illnesss such as soft, arthralgia pain due to rheumatism, injury of tendon and muscle fracture, uterine bleeding, threatened abortion, injury from falling down；
Sargentodoxa cuneata, is plants of Lardizabalaceae sargentodoxa cuneata（Sargentodoxa cuneata (Oliv.)Rehd. et Wils.）It is dry
Dry rattan, mild-natured bitter returns large intestine, Liver Channel , Cheongju thermal detoxifications, promoting blood circulation, wind-expelling pain-stopping.For abdominalgia with intestinal abscess, pathopyretic ulcer, warp
Close, dysmenorrhoea, tumbling and swelling, arthralgia pain due to rheumatism；
Aconiti preparata,radix, is the ranunculaceae plant rhizome of Chinese monkshood（Aconitum carmichaeliiDebx.）Dry the processed product of mother's root, taste
Pungent, hardship, property heat；The thoughts of returning home, liver,kidney,spleen warp, dispelling wind and eliminating dampness, antalgic are usually used in being used for wind-cold-dampness arthralgia, joint crymodynia, cold hernia
Have a pain and narcotic analgesic；
Wild aconite root, is the northern rhizome of Chinese monkshood of ranunculaceae plant（Aconitum kusnezoffiiReichb.）The processed product of dried root,
Pungent, hardship, property heat；The thoughts of returning home, liver,kidney,spleen warp；Dispelling wind and eliminating dampness, antalgic；For wind-cold-dampness arthralgia, arthralgia, Xin Fuleng
Bitterly, cold hernia is relieved pain.
In said components prescription, Radix Angelicae Sinensis and Ligusticum wallichii are monarch drug in a prescription, to the master that swollen and ache caused by soft tissue injury and injured bones and muscles
Therapeutic action is wanted, muscles and bones is hindered in outer, necessarily involves qi and blood and hinder in interior, train of thought damage, qi depression to blood stasis, then pain of feeling frustrated, blood stasis then swells,
Two medicines are with use, energy Synergistic, with blood circulation promoting and enriching, the function of promoting qi circulation and relieving pain；The bark of eucommia, teasel root are ministerial drug, injured bones and muscles influence
Liver kidney, wound planted agent, naturally in order to promote the healings of injured bones and muscles, it is necessary to which adjusting and reinforcing liver and kidney, the bark of eucommia, teasel root compatibility are used,
Can filling liver kidney, strengthening the bones and muscles, improvement caused by liver and kidney deficiency, the powerless symptom of muscles and bones；Double crows are with using, to caused by soft tissue and injured bones and muscles
Pain has significantly and quickly mitigation；Windproof simultaneous pair of controlling is sick, and the injury of the tissues easily brings arthralgia pain due to rheumatism, lockjaw etc. to human body,
Windproof to expel pathogenic wind from the body surface, expel endogenous wind to relieve convulsion stops convulsion, prevents aggravation and expansion；Above flavour of a drug are mutually cooperateed with, and are controlled outside interior benefit, right
Closed soft tissue injury and injured bones and muscles have great curative effect, to local swelling and pain, and activity is unfavorable, and there have to be accurate and fast
The improvement of speed.
As preferred technical scheme, it is made up of following components in parts by weight：
Radix Angelicae Sinensis：23-27 parts, Ligusticum wallichii：It is 23-27 parts, windproof：23-27 parts, peach kernel：11-13 parts, safflower：11-13 parts, the bark of eucommia：11-
13 parts, teasel root：11-13 parts, sargentodoxa cuneata：11-13 parts, aconiti preparata,radix：3-7 parts, wild aconite root：3-7 parts.Its is better.
As preferred technical scheme, it is made up of following components in parts by weight：
Radix Angelicae Sinensis：25 parts, Ligusticum wallichii：It is 25 parts, windproof：25 parts, peach kernel：12.5 parts, safflower：12.5 parts, the bark of eucommia：12.5 parts, teasel root：
12.5 parts, sargentodoxa cuneata：12.5 parts, aconiti preparata,radix：5 parts, wild aconite root：5 parts.Its effect can reach most preferably.
The second object of the present invention is to provide the pharmaceutical preparation that composition is made.
Described pharmaceutical preparation is preferably paste, or other external preparations.
The preparation method of the paste is：Powder is ground into after the component is weighed, the second for being 85-95% with volumetric concentration
Alcohol makees solvent, and diacolation collects percolate, reclaims ethanol to relative density 1.20-1.28（70℃）Clear cream, it is standby；Take raw rubber
Matrix is made in 30-35 parts of 20-30 parts of glue, 20-30 parts of rosin and zinc oxide, adds above-mentioned clear cream and mixes, coating is made, is applied
Cream, cut-out, Gai Cun, stripping and slicing are produced.
Percolation during extraction, it is preferred to use the percolation in Chinese Pharmacopoeia 2015 editions under liquid extract.
It is used as preferred technical scheme：24 mesh sieves are crossed after crushing.
It is used as preferred technical scheme：Ethanol volumetric concentration is 90%.
The preparation method of the present invention is simple, and cost is low.
In summary, the invention has advantages below：The composition of the present invention is relatively easy, and component is common Chinese medicine
Material, and external preparation is used, safe and reliable, Clinical practice has no obvious toxic-side effects in three months；The present invention is soft to closed
Tissue damage and injured bones and muscles have definite curative effect, are confirmed by the clinical practice in more than 10 years.With promoting blood circulation and removing blood stasis, detumescence stops
Based on pain, it is aided with filling liver kidney, strengthening the bones and muscles can go directly from medicines such as windproof, peach kernel, safflower, sargentodoxa cuneata, aconiti preparata,radix, wild aconite roots
Sick institute.The paste alleviates the pain of closed soft tissue injury and injured bones and muscles patient, easy to use, economical and practical, patient
It is acceptant, with significantly promoting the use prospect.
Embodiment
The present invention is described in detail below.
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
Embodiment 1
A kind of paste for being used to treat closed soft tissue injury and injured bones and muscles, is made up of following components in parts by weight：
Radix Angelicae Sinensis：20 parts, Ligusticum wallichii：It is 20 parts, windproof：20 parts, peach kernel：10 parts, safflower：10 parts, the bark of eucommia：10 parts, teasel root：10 parts, greatly
Blood rattan：10 parts, aconiti preparata,radix：2 parts, wild aconite root：2 parts；
Preparation method is：Powder is ground into after the component is weighed, with the ethanol as solvent that volumetric concentration is 90%, diacolation is collected
Percolate, reclaims ethanol to relative density 1.25（70℃）Clear cream, it is standby；Take 20 parts of raw rubber, 20 parts of rosin and zinc oxide
30 parts are made matrix, add above-mentioned clear cream and mix, coating is made, carry out painting cream, cut-out, Gai Cun, stripping and slicing is produced.
Embodiment 2
A kind of paste for being used to treat closed soft tissue injury and injured bones and muscles, is made up of following components in parts by weight：Radix Angelicae Sinensis：
30 parts, Ligusticum wallichii：It is 30 parts, windproof：30 parts, peach kernel：15 parts, safflower：15 parts, the bark of eucommia：15 parts, teasel root：15 parts, sargentodoxa cuneata：15 parts,
Aconiti preparata,radix：8 parts, wild aconite root：8 parts；
Preparation method is：Powder is ground into after the component is weighed, with the ethanol as solvent that volumetric concentration is 90%, diacolation is collected
Percolate, reclaims ethanol to relative density 1.25（70℃）Clear cream, it is standby；Take 30 parts of raw rubber, 30 parts of rosin and zinc oxide
35 parts are made matrix, add above-mentioned clear cream and mix, coating is made, carry out painting cream, cut-out, Gai Cun, stripping and slicing is produced.
Embodiment 3
A kind of paste for being used to treat closed soft tissue injury and injured bones and muscles, is made up of following components in parts by weight：Radix Angelicae Sinensis：
25 parts, Ligusticum wallichii：It is 25 parts, windproof：25 parts, peach kernel：12 parts, safflower：12 parts, the bark of eucommia：12 parts, teasel root：12 parts, sargentodoxa cuneata：12 parts,
Aconiti preparata,radix：5 parts, wild aconite root：5 parts；
Preparation method is：Powder is ground into after the component is weighed, with the ethanol as solvent that volumetric concentration is 90%, diacolation is collected
Percolate, reclaims ethanol to relative density 1.28（70℃）Clear cream, it is standby；Take 25 parts of raw rubber, 25 parts of rosin and zinc oxide
32 parts are made matrix, add above-mentioned clear cream and mix, coating is made, carry out painting cream, cut-out, Gai Cun, stripping and slicing is produced.
The clinical test treated for closed soft tissue injury and injured bones and muscles
Case scenario
This group of case is outpatient：All have an obvious trauma history, local swelling, has tender point or conscious pain, dysfunction,
X-ray film excludes fracture, abarticulation, bone joint infection disease and tumour person, is this group of object of observation；In 128 patients, its
Middle male 68, female 60；It is age 15-77 Sui, average 40.33 years old；The course of disease is most short 0.5 hour, most long 95 hours, and average 27.25
Hour；37 are dampened, 91 are sprained.
Treatment method
The patch ointment of the gained of the embodiment of the present invention 3, gets up once daily morning, before evening sleep once, altogether twice, is within 10 days
One course for the treatment of, altogether using 6 courses for the treatment of.
The standard of curative effect evaluation
Curative effect determinate standard is formulated with reference to relevant information：
Cure：Symptom is wholly absent, and mobility returns to level before wound；
It is effective：Symptom largely disappears or substantially mitigated, and mobility is recovered substantially；
Effectively：Symptom makes moderate progress, but still remains certain pain or uncomfortable；
It is invalid：Symptom is without improvement or aggravation.
Treatment results
Above-mentioned 128 cases, are cured：98；It is effective：18；Effectively:6；It is invalid：6, effective percentage is 95.3%, cure rate
For 76.6%, illustrate that the medicine of the present invention is notable for the therapeutic effect of closed soft tissue injury and injured bones and muscles；And no
Feed back obvious adverse reaction；In addition, in follow-up after treatment half a year, 98 of healing, only 3 recurrences, recurrence rate is very low.
Model case is illustrated：
So-and-so is paid, female, 57 years old, Sichuan people from Chengdu, sprain of ankle joint was seen a doctor for 3 hours, local pain, tenderness, swelling, red heat, x-ray
Check and fracture and dislocate without merging；After patch according to embodiment 4 is treated with method, symptom is wholly absent, and joint function recovery is just
Often, main physico-chemical examination index is normal；
Summer so-and-so, man, 35 years old, Sichuan Guangyuan people, sprain of shoulder joint, redness and swelling of joints, deformation, tenderness, disease of hand was sent out repeatedly
Make, joint movement function obstacle, after being treated according to the patch of embodiment 4 with method, symptom is wholly absent, and joint function recovery is just
Often, main physico-chemical examination index is normal.
Claims (8)
1. a kind of pharmaceutical composition for being used to treat closed soft tissue injury and injured bones and muscles, it is characterised in that by following heavy
Measure the component composition of part：
Radix Angelicae Sinensis：20-30 parts, Ligusticum wallichii：It is 20-30 parts, windproof：20-30 parts, peach kernel：10-15 parts, safflower：10-15 parts, the bark of eucommia：10-
15 parts, teasel root：10-15 parts, sargentodoxa cuneata：10-15 parts, aconiti preparata,radix：2-8 parts, wild aconite root：2-8 parts.
2. the pharmaceutical composition according to claim 1 for being used to treat closed soft tissue injury and injured bones and muscles, it is special
Levy and be, be made up of following components in parts by weight：
Radix Angelicae Sinensis：23-27 parts, Ligusticum wallichii：It is 23-27 parts, windproof：23-27 parts, peach kernel：11-13 parts, safflower：11-13 parts, the bark of eucommia：11-
13 parts, teasel root：11-13 parts, sargentodoxa cuneata：11-13 parts, aconiti preparata,radix：3-7 parts, wild aconite root：3-7 parts.
3. the pharmaceutical composition according to claim 2 for being used to treat closed soft tissue injury and injured bones and muscles, it is special
Levy and be, wherein each bulk drug optimum weight part proportioning is：
Radix Angelicae Sinensis：25 parts, Ligusticum wallichii：It is 25 parts, windproof：25 parts, peach kernel：12.5 parts, safflower：12.5 parts, the bark of eucommia：12.5 parts, teasel root：
12.5 parts, sargentodoxa cuneata：12.5 parts, aconiti preparata,radix：5 parts, wild aconite root：5 parts.
4. the pharmaceutical preparation being made of the composition of claim 1-3 any one.
5. pharmaceutical preparation according to claim 4, it is characterised in that：The preparation is paste.
6. the preparation method of the paste described in claim 5, it is characterised in that：Powder is ground into after the component is weighed, body is used
The ethanol as solvent that product concentration is 85-95%, diacolation collects percolate, reclaims ethanol to relative density 1.20-1.28（70℃）
Clear cream, it is standby；Take 30-35 parts of 20-30 parts of raw rubber, 20-30 parts of rosin and zinc oxide that matrix is made, add above-mentioned clear cream and mix
It is even, coating is made, painting cream, cut-out, Gai Cun is carried out, stripping and slicing is produced.
7. preparation method according to claim 6, it is characterised in that：24 mesh sieves are crossed after crushing.
8. preparation method according to claim 6, it is characterised in that：Ethanol volumetric concentration is 90%.
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| CN108837038A (en) * | 2018-08-14 | 2018-11-20 | 耿马汇裕康药材生物科技有限责任公司 | A kind of Chinese medicinal composition for treating tendon injury |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106581235A (en) * | 2016-12-21 | 2017-04-26 | 四川何天祺医院管理有限公司 | Pharmaceutical composition for treatment of soft tissue injuries |
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| CN106581235A (en) * | 2016-12-21 | 2017-04-26 | 四川何天祺医院管理有限公司 | Pharmaceutical composition for treatment of soft tissue injuries |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108837038A (en) * | 2018-08-14 | 2018-11-20 | 耿马汇裕康药材生物科技有限责任公司 | A kind of Chinese medicinal composition for treating tendon injury |
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Application publication date: 20171020 |