CN1075877A - A kind of preparation method of burn ointment - Google Patents

Abstract

The present invention introduces a kind of preparation method of burn ointment.This burn cream is a raw material with the Radix Rehmanniae, Mirabilitum crystallina, Radix Et Rhizoma Rhei, Radix Sanguisorbae, Olibanum, Myrrha, Cortex Moutan, the Radix Angelicae Dahuricae, Radix Angelicae Sinensis, Cortex Phellodendri, Radix Arnebiae (Radix Lithospermi), Borneolum Syntheticum, in being soaked in Oleum Sesami substrate, heat in short-term to 80 ℃ after 24～48 hours, and add excipient beeswax gradually.

This kind system cream method, not only having changed traditional tempering is main system cream method, to safeguarding the Chinese medicine character, keeps pharmacological property, improving curative effect has good action; And have the medicine source side just, make simple, low price, advantage such as evident in efficacy; Use value is widely arranged.

Description

A kind of preparation method of burn ointment

The present invention relates to a kind of Chinese medicine unguentum preparation method that empyrosis is used of curing.

Burn, comprise scald and chemical burn, electric burn, be the mankind's more common wound slight illness in daily production, life.Therefore, the treatment burn medicine is the medicine a kind of commonly used in the medicine.

At present, treat the medicine for external use of burn wound both at home and abroad, its Chinese medicine and western medicine burn cream, the class of loosing are primary raw material with silver sulfadiazine, mafenide, anaesthesine generally; In recent years domestic have the people to replace silver sulfadiazine with zinc sulfadiazine again.More than this class Western medicine gram can make wound surface drying, subcrustal healing, but have the deficiency of wound pain and the intensification of carrying out property of slough.1988, the method that domestic someone again adopts Chinese and western medicine to combine was developed moist expose burn ointment, had solved the problem of carrying out property of pain and slough intensification; But its same price comparison costliness, medicine source inconvenience with aforementioned Western medicine; And dosage is suitable many, does not fit into basic unit, and promote the use of in rural area patient at one's own expense.

A common class is cured the Chinese patent medicine of burn, and as DIEDA WANHUAYOU, Comfrey Balm and so on, not only coating is inconvenient, breathability is poor, and curative effect is not good enough yet.

In addition, in traditional Chinese medicine unguentum preparation, how to temper with warm fire, this practice centering property of medicine flavor, efficacy exertion is unfavorable.

Task of the present invention provide a kind ofly have that anti-inflammatory analgetic is fast, short treating period, anti-infectious function is strong, granulation promoting good, the medicine source is wide, low-cost, can cure the preparation method of the full Chinese medicine burn ointment of burn and scald.

Now specific embodiments of the present invention is expressed as follows:

According to theory of Chinese medical science: " basic pathogenesis of burn is ' wound ', rather than pyretic toxicity, makes the stasis of blood due to wound.The wound surface that the slough that the burn back produces forms is the performance of blood stasis.

Through long-term practice, the inventor thinks: deep burn pathogenesis and fire-toxin and blood stasis all have substantial connection, treat this disease and answer promoting blood circulation by regulating nutrient QI, blood stasis dispelling, pain relieving; Heat-clearing and toxic substances removing, moisturize life.For pharmaceutically-active performances such as guarantee blood circulation promoting and blood stasis dispelling, must there be-moistens environment; So establishing with the Oleum Sesami Cera Flava is substrate, select that Radix Angelicae Sinensis, Olibanum, Myrrha, Cortex Moutan etc. are invigorated blood circulation for use, the usefulness of blood stasis dispelling, pain relieving; Select for use Cortex Phellodendri, Radix Et Rhizoma Rhei, Radix Sanguisorbae, Radix Arnebiae (Radix Lithospermi), Mirabilitum crystallina, Borneolum Syntheticum etc. to make the usefulness of heat-clearing and toxic substances removing.

Feature of the present invention is: with the preparation of pure Chinese medicine, concrete method for making is will fill a prescription earlier after former medicine puts into Oleum Sesami substrate and soak 24～48 hours, is warmed to 80 ℃ of filtered through gauze again, and adding Cera Flava etc. is mixed with cream.

Its compatibility of burn ointment of making according to above method is:

The Radix Rehmanniae 40～60 gram Mirabilitum crystallinas 50～70 grams

Radix Et Rhizoma Rhei 40～60 gram Radix Sanguisorbaes 40～60 grams

Olibanum 45～65 gram Myrrhas 45～65 grams

Cortex Moutan 30～50 gram Radixs Angelicae Dahuricae 30～50 grams

Radix Angelicae Sinensis 30～50 gram Cortex Phellodendris 25～35 grams

Radix Arnebiae (Radix Lithospermi) 5～15 gram Borneolum Syntheticums 10～20 grams

Oleum Sesami 3000～3500 gram Cera Flavas 150～250 grams

According to the burn ointment that above method is made, its advantage is:

1, owing to adopt immersion to reach heating method system cream in short-term, having changed traditional tempering is main system cream method, to safeguarding the Chinese medicine character, keep pharmacological property that the raising therapeutic effect has good action.

2, burn ointment Gu the medicine source side just, is made simple owing to adopt pure Chinese medicine to make; Also have low price, eutherapeutic advantage simultaneously, help the patient and use.

The inventor has used the self-control burn ointment to 171 routine a variety of causes from since in the December, 1989, the inpatient of different burn surface area, the degree of depth carries out observation on Clinical Application, and cure rate reaches 100%.Now part patient treatment situation in detail is expressed as follows:

In therapeutic process, we adopt following compatibility:

The Radix Rehmanniae 50 gram Mirabilitum crystallinas 60 grams

Radix Et Rhizoma Rhei 50 gram Radix Sanguisorbaes 50 grams

Olibanum 55 gram Myrrhas 55 grams

The Cortex Moutan 40 gram Radixs Angelicae Dahuricae 40 grams

Radix Angelicae Sinensis 40 gram Cortex Phellodendris 30 grams

Radix Arnebiae (Radix Lithospermi) 10 gram Borneolum Syntheticums 15 grams

After earlier the former medicine of above prescription being put into 3000 gram Oleum Sesami during making and being soaked 24～48 hours, heat to 80 ℃; Filtered through gauze adds one-tenth cream such as Cera Flava solvent while hot.

Table one: the routine number of different burn causes:

Burn cause	Flame	Hot fluid	Chemistry	Electricity	Colophonium	Ulcer	Add up to
								The example number	61	93	9	3	3	2	171

Table two: burn surface area situation

Burn surface area	Below 30%	31％～50％	More than 50%	Add up to
					The example number	95	54	22	171

Table three: burn concentration situation

Burn concentration	Shallow II is main	Dark II is main	III is main	Add up to
						78	67	26	171

Below all cure.

Case is introduced:

Example one: admission number 3038,20 years old, male, workman.Fall in people's high temperature dilute sulfuric acid solution to scald down behind glue, perineum, buttocks, the two lower limb and be admitted to hospital the gross area 41%, light 27%, depth 14% in three hours.With profit agent burn cream treatment 12 days, most of agent face healing, all healings in 22 days, no function influence.

Example two: admission number 2977,2.5 years old, boy.Boiling water burn lower limb, buttocks perineal position, two lower limb, the gross area 43%, light 3%, depth 35%, III ° 5%.Continuing to control the Liao Dynasty with profit agent burn cream controlled pre-in 38 days.

Example three: admission number 3375,33 years old, male.The oil depot workman.Whole body gasoline flame burn changed my institute over to by Chaling County hospital after 2 days, and the gross area 78%, depth are main.Leave hospital with burn ointment treatment recovery from illness in 33 days.

Example four: admission number 3023,23 years old, male, workman.Right hand electric burn was admitted to hospital in 6 hours, and preventing from scar is left hospital in burn ointment treatment recovery from illness in 23 days.

Example five: admission number 3004,30 years old, male, workman.A left side is that molten iron burn was admitted to hospital in 2 hours, area 1.5% III °.Burn ointment treatment recovery from illness in 35 days, not skin-grafting.

Claims (3)

1, a kind of preparation method of burn ointment is characterized in that described unguentum prepares with pure Chinese medicine; Its concrete method for making is after earlier formula material being put into Oleum Sesami substrate and soaking 24～48 hours, directly to be warmed to 80 ℃; Filtered through gauze adds the Cera Flava solvent while hot and becomes cream.

2, burn ointment according to claim 1, its compatibility of drugs is as follows:

The Radix Rehmanniae 40～60 gram Mirabilitum crystallinas 50～70 grams

Radix Et Rhizoma Rhei 40～60 gram Radix Sanguisorbaes 40～60 grams

Olibanum 45～65 gram Myrrhas 45～65 grams

Cortex Moutan 30～50 gram Radixs Angelicae Dahuricae 30～50 grams

Radix Angelicae Sinensis 30～50 gram Cortex Phellodendris 25～35 grams

Radix Arnebiae (Radix Lithospermi) 5～15 gram Borneolum Syntheticums 10～20 grams

Oleum Sesami 3000～3500 gram Cera Flavas 150～250 grams

3, according to claim 1 and 2 described burn ointments, its best former medicine compatibility is:

The Radix Rehmanniae 50 gram Mirabilitum crystallinas 60 grams

Radix Et Rhizoma Rhei 50 gram Radix Sanguisorbaes 50 grams

Olibanum 55 gram Myrrhas 55 grams

The Cortex Moutan 40 gram Radixs Angelicae Dahuricae 40 grams

Radix Angelicae Sinensis 40 gram Cortex Phellodendris 30 grams

Radix Arnebiae (Radix Lithospermi) 10 gram Borneolum Syntheticums 15 grams

Oleum Sesami 3000 gram Cera Flavas 150～250 grams