CN108245602B - A topical Chinese medicinal composition for treating dermatoses - Google Patents
A topical Chinese medicinal composition for treating dermatoses Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention discloses an external traditional Chinese medicine composition for treating skin diseases, which is prepared by the following raw materials in parts by weight through a percolation method or a soaking method: 50-200 parts of dragon's blood, 30-80 parts of lithospermum, 12-30 parts of radix sophorae flavescentis, 12-30 parts of honeysuckle and 10-30 parts of liquorice; the external traditional Chinese medicine composition is concentrated into liquid extract or dried into powder, then matrix and auxiliary materials are added and mixed evenly, and the external traditional Chinese medicine preparation can be prepared according to the conventional method in the field. The traditional Chinese medicine composition and the preparation have the effects of diminishing inflammation, sterilizing, relieving itching, healing wounds and promoting tissue regeneration, can quickly relieve skin inflammatory reaction, have obvious curative effect on diseases such as acne, furuncle and the like, and have good effect on healing and recovering skin lesions caused by corresponding diseases.
Description
Technical Field
The invention relates to an external traditional Chinese medicine composition for treating skin diseases, in particular to an external traditional Chinese medicine composition for treating furuncle and acne, belonging to the technical field of external traditional Chinese medicine preparations.
Background
When the traditional Chinese medicine is used for treating inflammation and infection such as acne and furuncle, in the field of western medicine treatment, antibiotics, hormones and antifungal medicines are used, so that the side effect is large, the recurrence is easy, and scars can be formed after healing.
The traditional Chinese medicine is mainly attributed to 'internal damp-heat and external wind-evil and heat evil', and the treatment with the medicines for clearing heat and removing toxicity, dispelling wind and eliminating dampness can be said to be symptomatic medicine, but years of clinical practice shows that the simple evil-eliminating therapy can play a certain curative effect, but has three defects:
(1) although the effect is quick, the effect is obviously reduced after a plurality of days of treatment, and a long time is often needed for healing;
(2) for intractable patients, especially those who are not cured by long-term illness, the effect is not good;
(3) after healing, the skin of a patient often has obvious scars, and the skin is particularly unacceptable for patients with diseases on the face.
The applicant of the invention tries to develop the invention by using a treatment idea of strengthening body resistance as a main part and eliminating evil as an auxiliary part, and clinical application shows that the invention has obvious curative effect on acne and furuncle, has special effect on recovery of skin damage and scar after disease elimination, can quickly cure acne and furuncle after most patients (including patients who are not cured for a long time before treatment) are treated by the formula, basically recovers the skin to a normal state, and has no scar after most patients are cured, which is particularly important for patients with diseases on the face.
Disclosure of Invention
The invention aims to solve the technical problem of providing an external traditional Chinese medicine composition for treating skin diseases aiming at the defects in the prior art, the traditional Chinese medicine composition has the effects of diminishing inflammation, sterilizing, relieving itching, healing wounds and promoting tissue regeneration, can quickly relieve skin inflammatory reaction, has obvious curative effects on diseases such as acne, furuncle and the like, and has good effects on healing and recovering skin lesions caused by corresponding diseases.
In order to achieve the purpose, the invention adopts the following technical scheme:
a topical Chinese medicinal composition for treating dermatogic disease is prepared from the following raw materials by percolation or soaking method: 50-200 parts of dragon's blood, 30-80 parts of lithospermum, 12-30 parts of radix sophorae flavescentis, 12-30 parts of honeysuckle and 10-30 parts of liquorice.
In the technical scheme, the raw materials in parts by mass are preferably as follows: 100 parts of dragon's blood, 40 parts of lithospermum, 20 parts of sophora flavescens, 20 parts of honeysuckle and 12 parts of liquorice.
In the technical scheme, the external traditional Chinese medicine composition for treating the skin diseases is prepared by a percolation method, and the method comprises the following steps: grinding 30-80 parts of lithospermum, 12-30 parts of radix sophorae flavescentis, 12-30 parts of honeysuckle and 10-30 parts of liquorice into coarse powder, placing the coarse powder into a percolation cylinder, continuously adding 95 percent (volume fraction) of ethanol which is 12 times (volume: mass) of the coarse powder into the coarse powder from the upper part of the percolation cylinder, and dynamically leaching and extracting to obtain a leaching solution A; 50-200 parts of dragon's blood is dissolved in 95 percent ethanol with the volume of 4 times (volume: mass) to obtain liquid B; mixing the liquid A and the liquid B, standing for 24h, filtering, and diluting the evaporated liquid to 5-10 times of the total weight of the raw materials (volume: mass) to obtain the topical Chinese medicinal composition for treating dermatosis;
preferably, the 12 times amount refers to the volume of 95% ethanol: the mass of the coarse powder is 12: 1; the 4 times of the ethanol refers to the volume of 95% ethanol: the mass of the dragon's blood is 4: 1; the 5-10 times refers to the volume after constant volume: 5-10 of the total mass of the raw materials: 1;
preferably, the particle size of the coarse powder is 0.1-0.8 cm;
preferably, when 12 times of 95% ethanol of the coarse powder is continuously added to the coarse powder from the upper part of the percolation cylinder for dynamic leaching extraction, the 95% ethanol is added within 20-30 h;
preferably, the temperature of evaporation does not exceed 65 ℃.
In the technical scheme, the external traditional Chinese medicine composition for treating the skin diseases is prepared by a soaking method, and the method comprises the following steps: grinding 50-200 parts of dragon's blood, 30-80 parts of lithospermum, 12-30 parts of radix sophorae flavescentis, 12-30 parts of honeysuckle and 10-30 parts of liquorice into coarse powder, soaking the coarse powder in 95% ethanol with the amount of 10 times (volume: mass) of the coarse powder for 4-5 days, stirring the coarse powder for several times every day, filtering the mixture, and fixing the volume of the filtrate to 5-10 times (volume: mass) of the total mass of the raw materials to obtain the external traditional Chinese medicine composition for treating the skin diseases;
preferably, the 10-fold amount refers to the volume of 95% ethanol: the mass of the coarse powder is 10: 1; the 5-10 times refers to the volume after constant volume: 5-10 of the total mass of the raw materials: 1;
preferably, the particle size of the coarse powder is 0.1-0.8 cm.
The invention also provides an external traditional Chinese medicine preparation for treating skin diseases, which is prepared by concentrating the external traditional Chinese medicine composition obtained by the percolation method or the soaking method into fluid extract or drying the fluid extract into powder, then adding the matrix commonly used in the field, uniformly mixing the mixture and preparing the acceptable preparation according to the conventional method in the field;
preferably, the dosage form is any one of ointment, suppository, film agent, lotion or emulsion;
preferably, the mass ratio of the matrix to the external traditional Chinese medicine composition is 1-20: 1-10, preferably 5-10: 1 to 6;
preferably, the base is a base commonly used in the art, such as white petrolatum, lanolin, and the like.
The external traditional Chinese medicine composition for treating the skin diseases and the external traditional Chinese medicine preparation for treating the skin diseases can be used for treating the skin diseases, in particular for treating furuncle and acne. For treating furuncle, the topical Chinese medicinal composition or topical Chinese medicinal preparation is dipped in absorbent cotton and applied to affected part 2-3 times per day, with the dosage enough to uniformly cover the affected part; for treating acne, the topical Chinese medicinal composition or topical Chinese medicinal preparation is applied to affected part 1-2 times daily with absorbent cotton, and the dosage is enough to uniformly cover the affected part.
In the invention, dragon's blood is used as a monarch drug: sanguis Draxonis has effects in promoting blood circulation, dispelling blood stasis, relieving pain, stopping bleeding, healing sore, and promoting granulation. The formula mainly applies the body resistance strengthening effect of healing sore and promoting granulation, stimulates the self-repairing and healing capability of the skin, resists diseases through the autoimmune function and the hair growth function of the human body, and helps the self-repairing of skin damage.
In the invention, the lithospermum, the honeysuckle and the radix sophorae flavescentis are used as ministerial drugs: the lithospermum has the effects of clearing heat and cooling blood, promoting blood circulation and removing toxicity, promoting eruption and eliminating spots, the honeysuckle has the effects of clearing heat and removing toxicity, dispelling wind and dissipating heat, the radix sophorae flavescentis has the effects of clearing heat and drying dampness, promoting urination and relieving itching, the efficacy of the dragon blood can be brought into play by clearing heat, dampness and wind evil of a patient, and the effects of reducing pain and itching of the patient are realized together with the dragon blood.
In the invention, liquorice is used as a guiding drug. The liquorice can relieve spasm and pain, and harmonize the effects of the other drugs, so that the effects of guiding the drugs into the interior and harmonizing the drug properties are achieved in the formula, the effect of the monarch drugs and the ministerial drugs can be brought into play, and the drug stimulation is reduced.
From the perspective of modern clinical medicine and pharmacology, on one hand, the dragon blood can resist inflammation, reduce swelling, reduce purulent secretion and accelerate wound healing, and on the other hand, the dragon blood also has different degrees of inhibition effects on epidermoid pathogenic fungi and bacteria; the radix Arnebiae has antiinflammatory, antifungal, and active oxygen scavenging effects; the honeysuckle has broad-spectrum antibacterial, antiviral, antipyretic and anti-inflammatory effects; radix Sophorae Flavescentis has antiviral, antiallergic and antiinflammatory effects; glycyrrhiza also has antioxidant, antibacterial and anti-inflammatory activity. The recipe is also supported by the theory and practice of pharmacology.
The traditional Chinese medicine composition and the traditional Chinese medicine preparation provided by the invention can effectively inhibit inflammatory reaction, sterilize and relieve itching by matching the medicines, quickly cure diseases, and further promote healing and recovery of skin lesions, so that the skin lesion parts of patients are intact as before, and the traditional Chinese medicine composition and the traditional Chinese medicine preparation have no toxic or side effect.
Detailed Description
The following detailed description of the embodiments of the present invention is provided, but the present invention is not limited to the following descriptions:
example 1:
a topical Chinese medicinal composition for treating dermatogic disease is prepared by the following method:
taking 100g of dragon's blood, 40g of lithospermum, 20g of sophora flavescens, 20g of honeysuckle and 12g of liquorice, grinding into coarse powder (the particle size of the coarse powder is 0.1-0.8cm, the coarse powder is sieved by a second sieve, and the aperture of the second sieve is 0.85cm), uniformly mixing, soaking for 5 days by 2000ml of 95% ethanol, stirring for 3 times per day, filtering, squeezing dregs of a decoction, filtering, combining the filtrates, and fixing the volume of the filtrate to 2000ml to obtain the external traditional Chinese medicine composition for treating the skin diseases.
Example 2:
a topical Chinese medicinal composition for treating dermatogic disease is prepared by the following method:
taking 60g of lithospermum, 28g of radix sophorae flavescentis, 28g of honeysuckle and 20g of liquorice, grinding the raw materials into coarse powder (the particle size of the coarse powder is 0.1-0.8cm, the coarse powder passes through a second sieve, and the aperture of the second sieve is 0.85cm), placing the coarse powder into a percolation cylinder, continuously adding 1600ml of 95% ethanol into the coarse powder from the upper part of the percolation cylinder, and dynamically leaching and extracting, wherein the outflow speed of a percolation solution is 1-3ml/min, and the obtained leaching solution is liquid A; dissolving 200g of sanguis Draxonis in 800ml of 95% ethanol to obtain liquid B; mixing the liquid A and the liquid B, standing for 24h, filtering, concentrating the filtrate at 50 deg.C under reduced pressure to obtain liquid, and diluting with 95% ethanol to 1800ml to obtain the topical Chinese medicinal composition for treating dermatosis.
Example 3:
a topical Chinese medicinal composition for treating dermatogic disease is prepared by the following method:
80g of dragon's blood, 50g of lithospermum, 20g of sophora flavescens, 20g of honeysuckle and 15g of liquorice are taken, ground into coarse powder (the particle size of the coarse powder is 0.1-0.8cm, the coarse powder is sieved by a second sieve, and the aperture of the second sieve is 0.85cm), evenly mixed, soaked in 2000ml of 95% ethanol for 5 days, stirred for 3 times every day, filtered, and the filtrate is subjected to constant volume to 2000ml, so that the external traditional Chinese medicine composition for treating the skin diseases is obtained.
Example 4:
a topical Chinese medicinal preparation for treating dermatogic disease is prepared from the topical Chinese medicinal composition of example 2 by concentrating under reduced pressure to obtain fluid extract with density of 1.10-1.30, adding 800g white vaseline and 100g lanolin per 100g fluid extract, heating, and mixing to obtain ointment.
The clinical curative effect is as follows: 198 clinical observations of the external traditional Chinese medicine composition for treating skin diseases, which is obtained in example 1, on furuncle and swellings:
1. patient grouping
All patients are from outpatient or inpatient of hospital, and are diagnosed with furuncle and swelling according to the traditional Chinese medicine syndrome differentiation method, and 198 patients are 133 patients with age of 16-49 years in male, 65 patients with age of 17-42 years in female.
2. Method of treatment
The external traditional Chinese medicine composition in the example 1 is dipped in absorbent cotton and is smeared on the affected part for 2-3 times a day, 0.5-3ml each time, and the dosage is determined to uniformly cover the affected part for 5-15 days.
3. Criteria for therapeutic effect
And (3) curing: the disease is effectively and thoroughly treated, and the corresponding symptoms completely disappear;
the effect is shown: the disease is effectively treated, and the symptoms are obviously relieved but not completely disappeared;
and (4) invalidation: the medicine has almost no therapeutic effect on diseases, and the disease symptoms are not relieved;
and (3) relapse: the disease has recurrence phenomenon within 6-12 months after healing.
4. Results
As shown in table 1:
table 1: table for observing therapeutic effects of the topical Chinese medicinal composition obtained in example 1 on furuncle
As can be seen from table 1, the external traditional Chinese medicine composition obtained in example 1 of the present invention has an effective rate of 98.46% for treating furuncle and no recurrence; the skin injury of the cured patient is as good as the original skin injury, and no scar is left.
The clinical curative effect is two: the clinical observations of 131 cases of acne treatment by the external traditional Chinese medicine composition for treating skin diseases obtained in example 1:
1. patient grouping
All patients were from hospital outpatients or hospitalized patients, and were diagnosed with acne according to the traditional Chinese medicine syndrome differentiation method, and the number of patients was 131, wherein 59 male patients were 15-28 years old, and 72 female patients were 14-23 years old.
2. Method of treatment
The external traditional Chinese medicine composition in the example 1 is dipped in absorbent cotton and is applied to the affected part 1-2 times a day, 0.5-3ml each time, and the dosage is determined to uniformly cover the affected part for 5-40 days.
3. Criteria for therapeutic effect
And (3) curing: the disease is effectively and thoroughly treated, and the corresponding symptoms completely disappear;
the effect is shown: the disease is effectively treated, and the symptoms are obviously relieved but not completely disappeared;
and (4) invalidation: the medicine has almost no therapeutic effect on diseases, and the disease symptoms are not relieved;
and (3) relapse: the disease has recurrence phenomenon within 6-12 months after healing.
4. Results
As shown in table 2:
table 2: table for observing the therapeutic effects of the topical Chinese medicinal composition obtained in example 1 on acne
As can be seen from table 2, the external traditional Chinese medicine composition obtained in example 1 of the present invention has an effective rate of up to 100% when used for treating acne; the skin injury of the cured patient is as good as the original skin injury, and no scar is left.
The above examples are only for illustrating the technical concept and features of the present invention, and are not intended to limit the scope of the present invention. All equivalent changes or modifications made according to the spirit of the present invention should be covered within the protection scope of the present invention.
Claims (8)
1. An external traditional Chinese medicine composition for treating skin diseases is characterized by being prepared from the following raw materials in parts by mass through a percolation method: 50-200 parts of dragon's blood, 30-80 parts of lithospermum, 12-30 parts of radix sophorae flavescentis, 12-30 parts of honeysuckle and 10-30 parts of liquorice;
when the external traditional Chinese medicine composition is prepared by a percolation method, the preparation method comprises the following steps: grinding 30-80 parts of lithospermum, 12-30 parts of radix sophorae flavescentis, 12-30 parts of honeysuckle and 10-30 parts of liquorice into coarse powder, placing the coarse powder into a percolation cylinder, continuously adding 95% ethanol which is 12 times of the coarse powder into the coarse powder from the upper part of the percolation cylinder, and dynamically leaching and extracting to obtain a leaching solution A; dissolving 50-200 parts of dragon's blood in 4 times of 95% ethanol to obtain liquid B; mixing the liquid A and the liquid B, standing for 24h, filtering, and metering the volume of the liquid obtained after evaporation of the filtrate to 5-10 times of the total mass of the raw materials to obtain the external traditional Chinese medicine composition for treating skin diseases;
when the external traditional Chinese medicine composition is prepared by a soaking method, the external traditional Chinese medicine composition comprises the following steps: grinding 50-200 parts of dragon's blood, 30-80 parts of lithospermum, 12-30 parts of radix sophorae flavescentis, 12-30 parts of honeysuckle and 10-30 parts of liquorice into coarse powder, soaking the coarse powder in 95% ethanol in an amount which is 10 times that of the coarse powder for 4-5 days, stirring the mixture for several times every day, filtering the mixture, and fixing the volume of the filtrate to 5-10 times of the total mass of the raw materials to obtain the external traditional Chinese medicine composition for treating the skin diseases.
2. The external traditional Chinese medicine composition according to claim 1, which is prepared from the following raw materials in parts by mass: 100 parts of dragon's blood, 40 parts of lithospermum, 20 parts of sophora flavescens, 20 parts of honeysuckle and 12 parts of liquorice.
3. The topical Chinese medicinal composition according to claim 1, wherein when the topical Chinese medicinal composition is prepared by percolation, the 12 times amount refers to the volume of 95% ethanol: the mass of the coarse powder is 12: 1; the 4 times of the ethanol refers to the volume of 95% ethanol: the mass of the dragon's blood is 4: 1; the 5-10 times refers to the volume after constant volume: 5-10 of the total mass of the raw materials: 1.
4. the topical Chinese medicinal composition according to claim 1, wherein, when the topical Chinese medicinal composition is prepared by percolation, the coarse powder has a particle size of 0.1-0.8 cm; the evaporation temperature is not more than 65 ℃; continuously adding 12 times of 95% ethanol into the coarse powder from the upper part of the percolation cylinder, and dynamically leaching and extracting, wherein the 95% ethanol is added within 20-30 h.
5. The topical Chinese medicinal composition according to claim 1, wherein when the topical Chinese medicinal composition is prepared by soaking method, the coarse powder has a particle size of 0.1-0.8 cm; the 10 times amount refers to the volume of 95% ethanol: the mass of the coarse powder is 10: 1; the 5-10 times refers to the volume after constant volume: 5-10 of the total mass of the raw materials: 1.
6. an external traditional Chinese medicine preparation for treating skin diseases is characterized in that: the externally applied traditional Chinese medicine composition of claim 1 is concentrated into fluid extract or dried into powder, then matrix commonly used in the field is added and mixed evenly, and the externally applied traditional Chinese medicine composition is prepared into acceptable dosage forms according to the conventional method in the field.
7. The topical Chinese medicinal preparation according to claim 6, characterized in that: the dosage form is any one of ointment, suppository, pellicle, lotion or emulsion.
8. The topical Chinese medicinal preparation according to claim 6, characterized in that: the mass ratio of the matrix to the external traditional Chinese medicine composition is 1-20: 1-10.
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| CN109589372A (en) * | 2019-01-02 | 2019-04-09 | 江西乾坤堂健康科技有限公司 | A kind of compound book on Chinese herbal medicine antibacterial liquid and preparation method thereof |
| CN112316012A (en) * | 2020-11-19 | 2021-02-05 | 陕西康乐实业有限公司 | Moisturizing antibacterial gel and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1262943A (en) * | 1999-02-09 | 2000-08-16 | 夏进 | Skin ointment with functions of relieving inflammation, alleviating pain and inhibiting cicatrization |
| CN101073575A (en) * | 2006-05-16 | 2007-11-21 | 滕殿君 | Capsule for treating acne |
| CN102631413A (en) * | 2012-04-28 | 2012-08-15 | 董博 | Chinese medicinal composition for treating acne |
| CN103655753A (en) * | 2013-08-02 | 2014-03-26 | 上海惠林生物科技有限公司 | External-use Chinese herbal medicine quick-acting preparation for treating infant miliaria and preparation process thereof |
-
2018
- 2018-04-18 CN CN201810347942.5A patent/CN108245602B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1262943A (en) * | 1999-02-09 | 2000-08-16 | 夏进 | Skin ointment with functions of relieving inflammation, alleviating pain and inhibiting cicatrization |
| CN101073575A (en) * | 2006-05-16 | 2007-11-21 | 滕殿君 | Capsule for treating acne |
| CN102631413A (en) * | 2012-04-28 | 2012-08-15 | 董博 | Chinese medicinal composition for treating acne |
| CN103655753A (en) * | 2013-08-02 | 2014-03-26 | 上海惠林生物科技有限公司 | External-use Chinese herbal medicine quick-acting preparation for treating infant miliaria and preparation process thereof |
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