CN107582480A - A kind of anti-aging skin care product and preparation method thereof - Google Patents

A kind of anti-aging skin care product and preparation method thereof Download PDF

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Publication number
CN107582480A
CN107582480A CN201710838460.5A CN201710838460A CN107582480A CN 107582480 A CN107582480 A CN 107582480A CN 201710838460 A CN201710838460 A CN 201710838460A CN 107582480 A CN107582480 A CN 107582480A
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China
Prior art keywords
parts
skin care
care product
aging skin
mesoporous silicon
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CN201710838460.5A
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Chinese (zh)
Inventor
葛啸虎
陈海佳
王飞
王一飞
王小燕
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Guangzhou Saliai StemCell Science and Technology Co Ltd
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Priority to CN201710838460.5A priority Critical patent/CN107582480A/en
Publication of CN107582480A publication Critical patent/CN107582480A/en
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Abstract

The invention discloses a kind of anti-aging skin care product and preparation method thereof, the anti-aging skin care product is made up of the component of following parts by weight:Part A:1~8 part of 5~15 parts of Korean ginseng extract, 2~6 parts of bamboo extractive and Huai Goat;Part B:5~8 parts of 4~10 parts of mesoporous silicon, 2~4 parts of DPG, 0.5~2 part of polyoxyethylene stearyl base ether, 3~7 parts of glycerin monostearate and Emulsifier EL-60;C portion:20~40 parts of 2~8 parts of glycerine and water;D parts:1~5 part of 3~6 parts of vaseline and lanolin;E parts:0.1~1 part of pH adjusting agent.The anti-aging skin care product of the present invention has good collaboration anti-oxidant and moisture retention effect, can reduce skin water loss, have the effect of good slow release effect and long-acting anti-aging, avoid causing the waste of active ingredient.

Description

A kind of anti-aging skin care product and preparation method thereof
Technical field
The present invention relates to skin care field, and in particular to a kind of anti-aging skin care product and preparation method thereof.
Background technology
Skin care be it is important in global beauty and personal care industries segment market, and anti-aging skin care product is standby wherein It is concerned.Since ancient times, the mankind are directed to finding the active material with anti-aging effects always.The reason for causing skin senescence Mainly have:1) ultraviolet irradiation causes collagen to be lost in, so as to accelerate skin aging;2) attack of oxygen radical is led in vivo Cause skin injury;3) the fibroblast natural aging in skin.
In anti-aging skin care product on the market, there is burst effect, discharge or discharge big completely within a very short time Fractions of active ingredient, slow release effect is poor, does not possess the effect of lasting anti-aging, and anti-aging skin care product active ingredient is prominent Release and often lead to skin over-burden, waste active component;On the other hand, composition is single in anti-aging skin care product, anti-aging Can be limited.
The content of the invention
It is an object of the invention to overcome the deficiencies of the prior art and provide a kind of anti-aging skin care product, has comprehensively anti-ageing The effect of old and long-acting anti-aging.
It is another object of the present invention to provide a kind of preparation method of anti-aging skin care product.
To achieve the above object, the technical scheme that the present invention takes is as follows:
A kind of anti-aging skin care product, it is made up of the component of following parts by weight:
Part A:1~8 part of 5~15 parts of Korean ginseng extract, 2~6 parts of bamboo extractive and Huai Goat;
Part B:4~10 parts of mesoporous silicon, 2~4 parts of DPG, 0.5~2 part of polyoxyethylene stearyl base ether, single tristearin 5~8 parts of 3~7 parts of acid glyceride and Emulsifier EL-60;
C portion:20~40 parts of 2~8 parts of glycerine and water;
D parts:1~5 part of 3~6 parts of vaseline and lanolin;
E parts:0.1~1 part of pH adjusting agent.
Korean ginseng extract, bamboo extractive and Huai Goat all have good resist in above-mentioned anti-aging skin care product Oxidation effectiveness, skin metabolism can be promoted, three, which is used cooperatively, has good collaboration anti-aging effects, and delaying skin is old Change;Mesoporous silicon forms hydrogen bond by oxygen atom and the water-wet side of amphiphilic surfactant, and one layer of guarantor is formed at oil-water interfaces Sheath, delay the release of Korean ginseng extract, bamboo extractive and Huai Goat active ingredient, reach sustained release and it is long-acting anti-ageing Old effect, avoid the waste of active ingredient.
As the preferred embodiment of anti-aging skin care product of the present invention, it is made up of the component of following parts by weight:
Part A:4~7 parts of 7~10 parts of Korean ginseng extract, 3~5 parts of bamboo extractive and Huai Goat;
Part B:5~8 parts of mesoporous silicon, 2~4 parts of DPG, 0.5~2 part of polyoxyethylene stearyl base ether, monostearate 5~8 parts of 3~7 parts of glyceride and Emulsifier EL-60;
C portion:20~40 parts of 2~8 parts of glycerine and water;
D parts:1~5 part of 3~6 parts of vaseline and lanolin;
E parts:0.1~1 part of pH adjusting agent.
As the preferred embodiment of anti-aging skin care product of the present invention, it is made up of the component of following parts by weight:
Part A:5 parts of 8 parts of Korean ginseng extract, 4 parts of bamboo extractive and Huai Goat;
Part B:6 parts of mesoporous silicon, 2~4 parts of DPG, 0.5~2 part of polyoxyethylene stearyl base ether, monostearate are sweet 5~8 parts of 3~7 parts of grease and Emulsifier EL-60;
C portion:20~40 parts of 2~8 parts of glycerine and water;
D parts:1~5 part of 3~6 parts of vaseline and lanolin;
E parts:0.1~1 part of pH adjusting agent.
As the preferred embodiment of anti-aging skin care product of the present invention, the mesoporous silicon is that nano-hexagonal is mesoporous Silicon.
As the preferred embodiment of anti-aging skin care product of the present invention, the size of the mesoporous silicon for 5~ 50nm。
As the preferred embodiment of anti-aging skin care product of the present invention, the pH adjusting agent is citric acid, winestone At least one of acid, salicylic acid, triethanolamine.
The present invention also provides a kind of preparation method of any of the above-described kind of anti-aging skin care product, comprises the following steps:
(1) synthesising mesoporous silicon;
(2) each component raw material is weighed in proportion;
(3) part B is thoroughly mixed, ultrasonic disperse forms emulsifying agent;
(4) part A and C portion are thoroughly mixed to form aqueous phase in 45 DEG C of heating stirrings;
(5) D parts are heated with stirring to 70 DEG C~80 DEG C, are thoroughly mixed to form oil phase;
(6) emulsifying agent that step (3) obtains is mixed with the oil phase that step (5) obtains, is stirring evenly and then adding into aqueous phase, shape Resulting mixture, the pH value of pH agent regulation mixture is then added, obtains the anti-aging skin care product.
As the preferred embodiment of the preparation method of anti-aging skin care product of the present invention, the pH value of the mixture For 6~7.
Compared with prior art, the invention has the advantages that:
Korean ginseng extract, bamboo extractive and Huai Goat all have well in the anti-aging skin care product of the present invention Antioxidant effect, skin metabolism can be promoted, three, which is used cooperatively, has good collaboration anti-aging effects, delaying skin Aging;Mesoporous silicon forms hydrogen bond by oxygen atom and the water-wet side of amphiphilic surfactant, and one layer is formed at oil-water interfaces Protective layer, delay the release of Korean ginseng extract, bamboo extractive and Huai Goat active ingredient, reach sustained release and resist with long-acting The effect of aging, avoid the waste of active ingredient.
Brief description of the drawings
Fig. 1 is keratoderma moisture determination result figure.
Fig. 2 is the Koryo gracilis polysaccharide releasing result figure of the skin care item of Bag filter method determination experiment group and control group.
Embodiment
For the object, technical solutions and advantages of the present invention are better described, below in conjunction with specific embodiment to the present invention Further illustrate.It will be appreciated by those skilled in the art that specific embodiment described herein is only to explain the present invention, not For limiting the present invention.
Test method used in following embodiments is conventional method unless otherwise specified;Institute in following embodiments The material that uses, reagent etc., unless otherwise specified, are commercially obtained.
Korean ginseng extract is purchased from Xi'an Rui Ying bio tech ltd;Bamboo extractive is purchased from Xi'an Bai Chuan biologies section Skill is limited;Huai Goat is purchased from Xi'an You Shuo bio tech ltd.
Embodiment 1
A kind of embodiment of the preparation method of anti-aging skin care product of the present invention, the system of anti-aging skin care product described in the present embodiment Preparation Method is:
(1) synthesising mesoporous silicon;
1) using lauryl amine as template, it is dissolved in ethanol solution, and adds tetraethyl orthosilicate under agitation, room temperature Lower reaction 20h;
2) 1h is reacted respectively in 45 DEG C and 80 DEG C;
3) reaction product is placed in 1h under 90 DEG C of baking oven, obtains the hexagonal mesoporous silicon grain that size is 5~50nm.
(2) each component raw material is weighed in proportion
Part A:1 part of 5 parts of Korean ginseng extract, 3 parts of bamboo extractive and Huai Goat;
Part B:4 parts of mesoporous silicon, 3 parts of DPG, 0.5 part of polyoxyethylene stearyl base ether, 5 parts of glycerin monostearate With 8 parts of Emulsifier EL-60;
C portion:20 parts of 2 parts of glycerine and water;
D parts:3 parts of 3 parts of vaseline and lanolin;
E parts:0.2 part of citric acid.
(3) part B is thoroughly mixed, ultrasonic disperse forms emulsifying agent;
(4) part A and C portion are thoroughly mixed to form aqueous phase in 45 DEG C of heating stirrings;
(5) D parts are heated with stirring to 70 DEG C~80 DEG C, are thoroughly mixed to form oil phase;
(6) emulsifying agent that step (3) obtains is mixed with the oil phase that step (5) obtains, is stirring evenly and then adding into aqueous phase, shape Resulting mixture, the pH value of citric acid regulation mixture is then added to 6.5, obtains the anti-aging skin care product.
Embodiment 2
A kind of embodiment of the preparation method of anti-aging skin care product of the present invention, the system of anti-aging skin care product described in the present embodiment Preparation Method is:
(2) synthesising mesoporous silicon;
1) using lauryl amine as template, it is dissolved in ethanol solution, and adds tetraethyl orthosilicate under agitation, room temperature Lower reaction 20h;
2) 1h is reacted respectively in 45 DEG C and 80 DEG C;
3) reaction product is placed in 1h under 90 DEG C of baking oven, obtains the hexagonal mesoporous silicon grain that size is 5~50nm.
(2) each component raw material is weighed in proportion
Part A:8 parts of 15 parts of Korean ginseng extract, 6 parts of bamboo extractive and Huai Goat;
Part B:10 parts of mesoporous silicon, 3 parts of DPG, 1.5 parts of polyoxyethylene stearyl base ether, glycerin monostearate 7 8 parts of part and Emulsifier EL-60;
C portion:35 parts of 2 parts of glycerine and water;
D parts:4 parts of 5 parts of vaseline and lanolin;
E parts:0.3 part of 0.2 part of salicylic acid and tartaric acid.
(3) part B is thoroughly mixed, ultrasonic disperse forms emulsifying agent;
(4) part A and C portion are thoroughly mixed to form aqueous phase in 45 DEG C of heating stirrings;
(5) D parts are heated with stirring to 75 DEG C, are thoroughly mixed to form oil phase;
(6) emulsifying agent that step (3) obtains is mixed with the oil phase that step (5) obtains, is stirring evenly and then adding into aqueous phase, shape Resulting mixture, the pH value of salicylic acid and tartaric acid regulation mixture is then added to 6.8, obtains the anti-aging skin care product.
Embodiment 3
A kind of embodiment of the preparation method of anti-aging skin care product of the present invention, the system of anti-aging skin care product described in the present embodiment Preparation Method is:
(3) synthesising mesoporous silicon;
1) using lauryl amine as template, it is dissolved in ethanol solution, and adds tetraethyl orthosilicate under agitation, room temperature Lower reaction 20h;
2) 1h is reacted respectively in 45 DEG C and 80 DEG C;
3) reaction product is placed in 1h under 90 DEG C of baking oven, obtains the hexagonal mesoporous silicon grain that size is 5~50nm.
(2) each component raw material is weighed in proportion
Part A:7 parts of 7 parts of Korean ginseng extract, 3 parts of bamboo extractive and Huai Goat;
Part B:8 parts of mesoporous silicon, 4 parts of DPG, 1 part of polyoxyethylene stearyl base ether, 6 parts of glycerin monostearate and 5 parts of Emulsifier EL-60;
C portion:28 parts of 6 parts of glycerine and water;
D parts:4 parts of 4 parts of vaseline and lanolin;
E parts:1 part of triethanolamine.
(3) part B is thoroughly mixed, ultrasonic disperse forms emulsifying agent;
(4) part A and C portion are thoroughly mixed to form aqueous phase in 45 DEG C of heating stirrings;
(5) D parts are heated with stirring to 80 DEG C, are thoroughly mixed to form oil phase;
(6) emulsifying agent that step (3) obtains is mixed with the oil phase that step (5) obtains, is stirring evenly and then adding into aqueous phase, shape Resulting mixture, the pH value of triethanolamine regulation mixture is then added to 6, obtains the anti-aging skin care product.
Embodiment 4
A kind of embodiment of the preparation method of anti-aging skin care product of the present invention, the system of anti-aging skin care product described in the present embodiment Preparation Method is:
(4) synthesising mesoporous silicon;
1) using lauryl amine as template, it is dissolved in ethanol solution, and adds tetraethyl orthosilicate under agitation, room temperature Lower reaction 20h;
2) 1h is reacted respectively in 45 DEG C and 80 DEG C;
3) reaction product is placed in 1h under 90 DEG C of baking oven, obtains the hexagonal mesoporous silicon grain that size is 5~50nm.
(2) each component raw material is weighed in proportion
Part A:4 parts of 10 parts of Korean ginseng extract, 5 parts of bamboo extractive and Huai Goat;
Part B:6 parts of mesoporous silicon, 4 parts of DPG, 1 part of polyoxyethylene stearyl base ether, 4 parts of glycerin monostearate and 5 parts of Emulsifier EL-60;
C portion:35 parts of 3 parts of glycerine and water;
D parts:1 part of 6 parts of vaseline and lanolin;
E parts:0.2 part of citric acid.
(3) part B is thoroughly mixed, ultrasonic disperse forms emulsifying agent;
(4) part A and C portion are thoroughly mixed to form aqueous phase in 45 DEG C of heating stirrings;
(5) D parts are heated with stirring to 80 DEG C, are thoroughly mixed to form oil phase;
(6) emulsifying agent that step (3) obtains is mixed with the oil phase that step (5) obtains, is stirring evenly and then adding into aqueous phase, shape Resulting mixture, the pH value of citric acid regulation mixture is then added to 6.5, obtains the anti-aging skin care product.
Embodiment 5
A kind of embodiment of the preparation method of anti-aging skin care product of the present invention, the system of anti-aging skin care product described in the present embodiment Preparation Method is:
(5) synthesising mesoporous silicon;
1) using lauryl amine as template, it is dissolved in ethanol solution, and adds tetraethyl orthosilicate under agitation, room temperature Lower reaction 20h;
2) 1h is reacted respectively in 45 DEG C and 80 DEG C;
3) reaction product is placed in 1h under 90 DEG C of baking oven, obtains the hexagonal mesoporous silicon grain that size is 5~50nm.
(2) each component raw material is weighed in proportion
Part A:5 parts of 8 parts of Korean ginseng extract, 4 parts of bamboo extractive and Huai Goat;
Part B:6 parts of mesoporous silicon, 3 parts of DPG, 2 parts of polyoxyethylene stearyl base ether, 5 parts of glycerin monostearate and 6 parts of Emulsifier EL-60;
C portion:40 parts of 7 parts of glycerine and water;
D parts:4 parts of 5 parts of vaseline and lanolin;
E parts:0.8 part of bigcatkin willow acid regulator.
(3) part B is thoroughly mixed, ultrasonic disperse forms emulsifying agent;
(4) part A and C portion are thoroughly mixed to form aqueous phase in 45 DEG C of heating stirrings;
(5) D parts are heated with stirring to 80 DEG C, are thoroughly mixed to form oil phase;
(6) emulsifying agent that step (3) obtains is mixed with the oil phase that step (5) obtains, is stirring evenly and then adding into aqueous phase, shape Resulting mixture, the pH value of salicylic acid regulation mixture is then added to 6.0, obtains the anti-aging skin care product.
First, the anti-aging performance measurement of anti-aging skin care product
Using the skin care item prepared by embodiment 1~5 as experimental group, using the skin care item prepared by comparative example 1~3 as pair According to group, related efficacy test is carried out.The A phases of the skin care compositions of comparative example are made up of the component of table 1, other components and preparation Method is the same as embodiment 5.
Table 1
(1) superoxide anion removes measure
It is the water-soluble of 50mg/mL that skin care item prepared by embodiment 1~5 and comparative example 1~3 are configured into concentration respectively Liquid.0.1mL is taken to be separately added into NaOHs of the 1mL containing 557 μm of ol/L 16mmol/L Tris-HCl (pH=8.0), 1mL contains 45 μ Mol/L PMS 16mmol/L Tris-HCl (pH 8.0), and the 16mmol/L Tris-HCl of the NBT containing 108 μm of ol/L (pH=8.0).25 DEG C of warm bath 5min, light absorption value is surveyed under ELIASA 560nm, and calculating superoxide anion according to formula (1) removes Rate, as a result as shown in table 2.
Superoxide anion clearance rate=(1- sample cells A560/ control tube A560) × 100% (1)
Table 2
Superoxide anion is a kind of living radical caused by organism metabolism process, has close connection with skin aging System.As seen from the results in Table 2, the superoxide anion clearance rate of skin care item prepared by embodiment shows Koryo apparently higher than comparative example There is synergy, skin care compositions tool prepared by the present invention between conopsea extraction, bamboo extractive and Huai Goat three There is good collaboration antioxidation, be advantageous to delay skin aging.
(2) Hydroxyl radical-scavenging determines
It is the water-soluble of 50mg/mL that skin care item prepared by embodiment 1~5 and comparative example 1~3 are configured into concentration respectively Liquid.Take 0.1mL be separately added into 0.6mL reaction buffers (deoxyribose containing 2.67mmol/L and 0.13 mmol/L EDTA's 0.2mol/L pH=7.4 phosphate buffer), 0.4mmol/L ferrous sulfate 0.2 mL, 2.0mmol/L ascorbic acid 0.05mL, and 20mmol/L H2O20.05mL, 37 DEG C of warm bath 15min, added after taking-up 1% thiobarbituricacidα- 1mL and 2% trichloroacetic acid 1mL, the min of boiling water bath 15, in cooled on ice after taking-up, light absorption value is surveyed under ELIASA 532nm, according to formula (2) Scavenging action to hydroxyl free radical is calculated, as a result as shown in table 3.
Scavenging action to hydroxyl free radical=(1- sample cells A532/ control tube A532) × 100% (2)
Table 3
Hydroxy radical is the principal element for causing biologic artifact peroxide injury as active oxygen radical.Can by table 3 Know, the Scavenging action to hydroxyl free radical of skin care compositions prepared by embodiment shows Korean ginseng extract, the leaf of bamboo apparently higher than comparative example There is collaboration antioxidation between extract and Huai Goat three, being capable of effectively delaying skin aging.
(3) keratoderma moisture determination
Skin care compositions made from embodiment 1~5 and comparative example 1~3, each group selected 30 ages at 35~55 years old respectively Female volunteers, smearing skin care compositions on the face after volunteer's face cleaning, be used continuously 6 months, pass through skinanalysis apparatus (MC750, German CK) determines water content of stratum corneum, and test result is as shown in Figure 1.
Have in keratoderma with reference to water and the two kinds of moisture of free water, moisture can influence cuticula reclaimed water and The formation of grease sebum film, sebum film can prevent moisture excessive evaporation, softening skin, have important meaning to the anti-aging of skin Justice.As shown in Figure 1, after the skin care item that volunteer is prepared using embodiment, keratoderma water content is apparently higher than comparative example, table Bright Korean ginseng extract, bamboo extractive and Huai Goat triplicity can reduce skin water loss well, have More preferable moistening effect.
2nd, anti-aging skin care product is sustained effect measure
Using anti-aging skin care product prepared by embodiment 5 as experimental group, the difference of control group, control group and control group is set Part does not add mesoporous silicon only.
Using Bag filter method evaluation experimental group and sustained release effect of control group, using physiological saline as dissolution medium, timing Solution outside sampling detection bag filter, as a result as shown in Figure 2.
As shown in Figure 2, the release of experimental group is significantly lower than control group, and mesoporous silicon passes through oxygen atom and amphipathic surface-active The water-wet side of agent forms hydrogen bond, and layer protective layer is formed at oil-water interfaces, delays Korean ginseng extract, bamboo extractive and Chinese scholartree The release of rice extracts active ingredient, reach the effect of sustained release and long-acting anti-aging.
Result above shows that skin care item of the invention have good collaboration antioxidant effect and moisture retention, can reduce Skin water loss, there is the effect of good slow release effect and long-acting anti-aging.
Finally, it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention rather than the present invention is protected The limitation of scope is protected, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should Understand, technical scheme can be modified or equivalent substitution, without departing from the essence of technical solution of the present invention And scope.

Claims (8)

1. a kind of anti-aging skin care product, it is characterised in that be made up of the component of following parts by weight:
Part A:1~8 part of 5~15 parts of Korean ginseng extract, 2~6 parts of bamboo extractive and Huai Goat;
Part B:4~10 parts of mesoporous silicon, 2~4 parts of DPG, 0.5~2 part of polyoxyethylene stearyl base ether, monostearate are sweet 5~8 parts of 3~7 parts of grease and Emulsifier EL-60;
C portion:20~40 parts of 2~8 parts of glycerine and water;
D parts:1~5 part of 3~6 parts of vaseline and lanolin;
E parts:0.1~1 part of pH adjusting agent.
2. anti-aging skin care product according to claim 1, it is characterised in that be made up of the component of following parts by weight:
Part A:4~7 parts of 7~10 parts of Korean ginseng extract, 3~5 parts of bamboo extractive and Huai Goat;
Part B:5~8 parts of mesoporous silicon, 2~4 parts of DPG, 0.5~2 part of polyoxyethylene stearyl base ether, glycerol monostearate 5~8 parts of 3~7 parts of ester and Emulsifier EL-60;
C portion:20~40 parts of 2~8 parts of glycerine and water;
D parts:1~5 part of 3~6 parts of vaseline and lanolin;
E parts:0.1~1 part of pH adjusting agent.
3. anti-aging skin care product according to claim 1, it is characterised in that be made up of the component of following parts by weight:
Part A:5 parts of 8 parts of Korean ginseng extract, 4 parts of bamboo extractive and Huai Goat;
Part B:6 parts of mesoporous silicon, 2~4 parts of DPG, 0.5~2 part of polyoxyethylene stearyl base ether, glycerin monostearate 3 ~7 parts and 5~8 parts of Emulsifier EL-60;
C portion:20~40 parts of 2~8 parts of glycerine and water;
D parts:1~5 part of 3~6 parts of vaseline and lanolin;
E parts:0.1~1 part of pH adjusting agent.
4. anti-aging skin care product according to claim 1, it is characterised in that the mesoporous silicon is nano-hexagonal mesoporous silicon.
5. anti-aging skin care product according to claim 1, it is characterised in that the size of the mesoporous silicon is 5~50nm.
6. anti-aging skin care product according to claim 1, it is characterised in that the pH adjusting agent be citric acid, tartaric acid, At least one of salicylic acid, triethanolamine.
7. the preparation method of the anti-aging skin care product according to any one of claim 1~6, it is characterised in that including following Step:
(1) synthesising mesoporous silicon;
(2) each component raw material is weighed in proportion;
(3) part B is thoroughly mixed, ultrasonic disperse forms emulsifying agent;
(4) part A and C portion are thoroughly mixed to form aqueous phase in 45 DEG C of heating stirrings;
(5) D parts are heated with stirring to 70 DEG C~80 DEG C, are thoroughly mixed to form oil phase;
(6) emulsifying agent that step (3) obtains is mixed with the oil phase that step (5) obtains, is stirring evenly and then adding into aqueous phase, formed mixed Compound, the pH value of pH agent regulation mixture is then added, obtains the anti-aging skin care product.
8. the preparation method of anti-aging skin care product according to claim 7, it is characterised in that the pH value of the mixture is 6~7.
CN201710838460.5A 2017-09-15 2017-09-15 A kind of anti-aging skin care product and preparation method thereof Withdrawn CN107582480A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815065A (en) * 2018-05-28 2018-11-16 苏州郎旭志远科技有限公司 A kind of whitening and spot eliminating cream and preparation method thereof with lasting slow releasing function

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101693000A (en) * 2009-08-28 2010-04-14 许庆华 Technology for producing extract solution from pagodatree flower bud
CN103356425A (en) * 2013-05-23 2013-10-23 上海珍馨化工科技有限公司 Peel-off ginseng mask and preparation method of mask

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101693000A (en) * 2009-08-28 2010-04-14 许庆华 Technology for producing extract solution from pagodatree flower bud
CN103356425A (en) * 2013-05-23 2013-10-23 上海珍馨化工科技有限公司 Peel-off ginseng mask and preparation method of mask

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815065A (en) * 2018-05-28 2018-11-16 苏州郎旭志远科技有限公司 A kind of whitening and spot eliminating cream and preparation method thereof with lasting slow releasing function

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