CN107569410A - A kind of amino acid cleansing breast and preparation method thereof - Google Patents
A kind of amino acid cleansing breast and preparation method thereof Download PDFInfo
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- CN107569410A CN107569410A CN201710919271.0A CN201710919271A CN107569410A CN 107569410 A CN107569410 A CN 107569410A CN 201710919271 A CN201710919271 A CN 201710919271A CN 107569410 A CN107569410 A CN 107569410A
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Abstract
The invention provides a kind of amino acid cleansing breast and preparation method thereof, the amino acid cleansing breast includes amino acid surfactant 10 50%, amphoteric surfactant 1 10%, vegetable fat 3 20% by mass percentage, thickener 0.1 5%, surplus is deionized water.The amino acid cleansing breast foaming abundancy of the present invention, fat content are up to 20%, surfactant, vegetable fat and thickener synergy so that and amino acid cleansing breast not only has stronger cleaning moisture-retaining capacity, and with nourishing maintenance effect.
Description
Technical field
The invention belongs to daily cosmetics field, is related to a kind of amino acid cleansing breast and preparation method thereof, and in particular to one
The high fat content of kind is up to 20% amino acid cleansing breast and preparation method thereof.
Background technology
In recent years, the skin problem of China resident increases increasingly, is mainly shown as that dry water shortage, sensitive fragility, spot are dark
Heavy, dark sore acne etc., these skin problems are mainly asked by air pollutions such as haze, sandstorm, ultraviolet irradiation, vehicle exhausts
Caused by topic, and the city haze frequently occurred recently has further aggravated the burden of skin.Fine particle in haze, can be with
It is attached directly to skin surface, blocks pore, the skin problem such as cause blackhead, pore thick.Face cleaning is the first step of skin care,
And the most important thing of skin care, only thoroughly remove the dirt of skin surface attachment and unnecessary grease, the skin care subsequently used
Nutritional ingredient can be just absorbed by the skin, and reach corresponding effect.
Face cleaning product on the market at present, can substantially be divided into soap base system, surfactant system, amino acid system and
Emulsification system.Wherein, soap base system decontamination degreasing ability is strong, but tight using rear skin water shortage, and cleaning is excessive, easily damages flesh
Skin；Surfactant system is gentleer relative to soap base system, and decontamination degreasing ability is moderate, but surfactant not do by easy cleaning
Only, remain more after washing, resting on skin surface has certain excitant；Amino acid surfactant is in faintly acid, with skin
The pH value on skin surface approaches, and skin-friendly is good, and cleaning strength is moderate, is remained after washing less, compared to soap base system and surfactant body
It is that the gentle degree of product is high, but equally exists the problem of using rear skin water shortage tight；Do not have after emulsification system face cleaning product use
There is the sense of discomfort that water shortage is tight, but foam is few, decontamination degreasing ability is poor, it is difficult to which consumer receives by Asian market.
The A of CN 106726698 disclose a kind of amino acid pattern mildy wash and preparation method thereof, the amino acid pattern mildy wash bag
Include 10-30wt% amino acid surfactants, 1-15wt% non-amino acid surfactant, 0.5-2wt% thickeners, 5-
30wt% NMFs, 0.2-2.5wt% nertralizers, 0.1-1wt% conditioners and deionized water, in neutrality, gentle pro-skin, safety
It is non-stimulated, can deep layer cleaning skin, mainly by add the NMFs such as glycerine, trehalose, Sodium Hyaluronate alleviate amino acid
The water shortage tight feeling that surfactant is brought, but the amino acid pattern mildy wash only has cleaning moisture-keeping functions, without maintenance
Nutritve function, and the composition such as including polyquaternium, there is certain excitant to sensitive fragile skin universal at present.
The A of CN 106491380 disclose a kind of special N- acylamino acids anion surfactant type face cleaning of face cleaning instrument
Breast/cream and preparation method thereof, the mildy wash/cream include the groups such as anion surfactant, beet alkali surface activator, grease
Point, gentle pro-skin is non-stimulated, can thoroughly remove dirt, sweat and grease in pore, but asking without what solution grease defoamed
The mass percent only 1-3% of the vegetable fat such as topic, the olive oil that contains, lavender oil, rose oil, without significantly repairing
Protect nourishing effect.
Face cleaning product on the market all more or less exist excitant is strong, wash after residual, foam is few, cleaning force is poor etc. asks
Topic, using rear skin occur tight water shortage, sensitive decortication, shouting pain impression, therefore it provides a kind of have cleaning moisturizing, grow
Support the gentle non-stimulated foam type face cleaning product of maintenance double effects, have great importance in daily cosmetics field with it is wide
Market prospects.
The content of the invention
For overcome the deficiencies in the prior art, the present invention provides a kind of amino acid cleansing breast and preparation method thereof, the ammonia
Base acid mildy wash foaming abundancy, fat content are up to 20%, and surfactant, vegetable fat and thickener coordinated, are one
Kind has the face cleaning product for washing shield double effects concurrently.
To use following technical scheme up to this purpose, the present invention：
In a first aspect, the present invention provides a kind of amino acid cleansing breast, the amino acid cleansing breast includes by mass percentage：
In the amino acid cleansing breast of the present invention, amino acid surfactant and amphoteric surfactant have property temperature
With, foaming is abundant, cleaning force is moderate, foam stabilizing ability is strong the advantages of, both mating reactions add the foam volume of system, improve
Foam stability；Vegetable fat has the effect of nourishing skin, replenishing water and preserving moisture, forms layer protecting film in skin surface, greatly
Ground improves dry and astringent, the tight feeling of skin；Vegetable fat is coated on the interior phase of system by thickener, then active with amino acid surface
Agent and amphoteric surfactant are compounded, avoid vegetable fat and surfactant directly foam volume caused by compounding it is few,
The problems such as foaming characteristic is poor, foam easily disappears, system is unstable.Amino acid surfactant, amphoteric surfactant, vegetable fat and
Thickener acts synergistically under rational proportioning, and the amino acid cleansing breast of preparation is when the mass percent of vegetable fat is up to 20%
Still there is abundant foam, there is provided effective cleaning power, discharge grease while cleaning skin, reach the work(for nourishing moisturizing
Effect.
Preferably, mass percent of the amino acid surfactant in the amino acid cleansing breast is 10-50%,
Such as can be 10%, 12%, 15%, 18%, 20%, 22%, 25%, 28%, 30%, 32%, 35%, 38%, 40%,
42%th, 45%, 48% or 50%, preferably 20-40%, more preferably 40%.
Preferably, mass percent of the amphoteric surfactant in the amino acid cleansing breast is 1-10%, example
It such as can be 1%, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9% or 10%, preferably 5-10%, be more preferably
10%.
Preferably, mass percent of the vegetable fat in the amino acid cleansing breast is 3-20%, such as can be with
3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%, 18%,
19% or 20%, preferably 10-20%, more preferably 20%.
Preferably, mass percent of the thickener in the amino acid cleansing breast is 0.1-5%, such as can be
0.1%th, 0.2%, 0.5%, 0.8%, 1.0%, 1.2%, 1.5%, 1.8%, 2.0%, 2.2%, 2.5%, 2.8%,
3.0%th, 3.2%, 3.5%, 3.8%, 4.0%, 4.2%, 4.5%, 4.8% or 5.0%, preferably 0.1-2%, it is further excellent
Elect 2% as.
Preferably, the amino acid surfactant includes cocounut oil acyl glycine potassium, sodium cocoyl glycinate, cocounut oil acyl paddy
In propylhomoserin potassium, sodium cocoyl glutamate, cocounut oil acyl disodium glutamate, cocoyl glutamic acid TEA salt or sodium lauroyl glutamate
Any one or at least two combination, preferably cocounut oil acyl glycine potassium.
Preferably, the amphoteric surfactant includes Cocoamidopropyl betaine, coco betaine, cocounut oil acyl two
In property guanidine-acetic acid sodium, lauroylamidopropyl betaine or lauryl betaine any one or at least two combination, preferably
For Cocoamidopropyl betaine.
Preferably, the vegetable fat is included in olive oil, coconut oil, Sweet Almond Oil, hippophae rhamnoides fruit oil or macadimia nut oil
Any one or at least two combination.
Preferably, the thickener includes the ammonium acryloyldime-thyltaurate/methacrylate of docosyl alcohol polyethers -25 friendship
Linked polymer, acrylic acid/C10-30 alkylol acrylamide acid esters cross-linked polymer, acrylate/C10-30 alkylol acrylamides acid esters crosslinking
In polymer or hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers any one or at least two combination,
Preferably ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25.
Preferably, the amino acid cleansing breast also include glycerine, EDETATE SODIUM or preservative in any one or at least
Two kinds of combination.
Preferably, mass percent of the glycerine in the amino acid cleansing breast is 1-20%, such as can be
1%th, 2%, 3%, 4%, 5%, 6%, 7%, 8%, 9%, 10%, 11%, 12%, 13%, 14%, 15%, 16%, 17%,
18%th, 19% or 20%, preferably 10-20%, more preferably 10%.
Preferably, mass percent of the EDETATE SODIUM in the amino acid cleansing breast is 0.05%.
Preferably, mass percent of the preservative in the amino acid cleansing breast is 0.01-1%, such as can be with
0.01%, 0.05%, 0.10%, 0.15%, 0.20%, 0.25%, 0.30%, 0.35%, 0.40%, 0.45%,
0.50%th, 0.55%, 0.60%, 0.65%, 0.70%, 0.75%, 0.80%, 0.85%, 0.90%, 0.95% or 1%, it is excellent
Elect 0.5% as.
Preferably, the amino acid cleansing breast includes by mass percentage：
Preferably, the amino acid cleansing breast includes by mass percentage：
Preferably, the amino acid cleansing breast includes by mass percentage：
Second aspect, the invention provides a kind of method of the amino acid cleansing breast prepared as described in relation to the first aspect, including
Following steps：
(1) glycerine, thickener, EDETATE SODIUM, preservative and deionized water are added into emulsification pot, stirring according to formula rate
Dissolving；
(2) vegetable fat is added after being heated to 60-100 DEG C, homogeneous, is cooled after constant temperature insulation；
(3) amino acid surfactant and amphoteric surfactant are added into emulsification pot according to formula rate, stirred,
Vacuum defoamation after cooling, that is, the amino acid cleansing breast is made.
Preferably, the temperature of step (1) described stirring and dissolving is 15-30 DEG C, for example, can be 15 DEG C, 16 DEG C, 17 DEG C, 18
DEG C, 19 DEG C, 20 DEG C, 21 DEG C, 22 DEG C, 23 DEG C, 24 DEG C, 25 DEG C, 26 DEG C, 27 DEG C, 28 DEG C, preferably 29 DEG C or 30 DEG C, 25 DEG C.
Preferably, the temperature of step (2) described heating is 70-90 DEG C, for example, can be 70 DEG C, 71 DEG C, 72 DEG C, 73 DEG C,
74℃、75℃、76℃、77℃、78℃、79℃、80℃、81℃、82℃、83℃、84℃、85℃、86℃、87℃、88℃、89
DEG C or 90 DEG C, preferably 80 DEG C.
Preferably, the time of step (2) described homogeneous is 1-10min, for example, can be 1min, 2min, 3min, 4min,
5min, 6min, 7min, 8min, 9min or 10min, preferably 1-5min, more preferably 3min.
Preferably, the time of step (2) described insulation is 5-30min, for example, can be 5min, 6min, 7min, 8min,
9min、10min、11min、12min、13min、14min、15min、16min、17min、18min、19min、20min、21min、
22min, 23min, 24min, 25min, 26min, 27min, 28min, 29min or 30min, preferably 10-25min, further
Preferably 20min.
Preferably, the temperature of step (2) described cooling is 50-70 DEG C, for example, can be 50 DEG C, 51 DEG C, 52 DEG C, 53 DEG C,
54℃、55℃、56℃、57℃、58℃、59℃、60℃、61℃、62℃、63℃、64℃、65℃、66℃、67℃、68℃、69
DEG C or 70 DEG C, preferably 60 DEG C.
Preferably, the temperature of step (3) described cooling is 30-50 DEG C, for example, can be 30 DEG C, 31 DEG C, 32 DEG C, 33 DEG C,
34℃、35℃、36℃、37℃、38℃、39℃、40℃、41℃、42℃、43℃、44℃、45℃、46℃、47℃、48℃、49
DEG C or 50 DEG C, preferably 45 DEG C.
Compared with prior art, the present invention has the advantages that：
(1) amino acid cleansing of the invention breast is added with vegetable fat, and not tight using rear skin, skin hydration rate is more than
70%；
(2) amino acid cleansing breast of the invention coordinates amphoteric surface using amino acid surfactant as primary surfactant
Activating agent, property is gentle, in not haemolysis under 0.2% concentration；
(3) vegetable fat is wrapped in thickener by amino acid cleansing breast of the invention, is significantly improved vegetable fat and is contained
Amount, avoid caused by vegetable fat and surfactant directly compounding foam volume is few, foaming characteristic is poor, foam easily disappears, system not
The problems such as stable, foaming abundancy, easily rinse；
(4) amino acid cleansing breast of the invention is in amino acid surfactant, amphoteric surfactant, vegetable fat and increasing
Thick dose acts synergistically under rational proportioning, still has abundant foam when the mass percent of vegetable fat is up to 20%,
Effective cleaning power is provide not only, and grease is discharged while cleaning skin, the effect of having reached nourishing moisturizing.
Brief description of the drawings
Fig. 1 is moisture content of skin curve map；
Fig. 2 is sample erythrocyte in vitro haemolysis irritant experiment result figure.
Embodiment
For the technological means and its effect that the present invention is taken is expanded on further, with reference to embodiments with accompanying drawing to this hair
It is bright to be further described.It is understood that embodiment described herein is used only for explaining the present invention, rather than
Limitation of the invention.
In the examples where no specific technique or condition is specified, according to the technology or condition described by document in the art,
Or carried out according to product description.Agents useful for same or the unreceipted production firm person of instrument, be can be by regular channel commercially available from
The conventional products of acquisition.
The amino acid cleansing of embodiment 1 breast (I)
Formula is shown in Table 1.
Table 1
Preparation method：
(1) by glycerine, the ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25,
EDETATE SODIUM, preservative and deionized water add according to formula rate emulsifies pot, stirring and dissolving at 25 DEG C；
(2) olive oil is added after being heated to 80 DEG C, homogeneous 3min, 20min is incubated, is cooled to 60 DEG C；
(3) cocounut oil acyl glycine potassium and Cocoamidopropyl betaine are added into emulsification pot according to formula rate, stirring is equal
It is even, 45 DEG C are cooled to, vacuum defoamation, that is, the amino acid cleansing breast is made.
The amino acid cleansing of embodiment 2 breast (II)
Formula is shown in Table 2.
Table 2
Preparation method：
(1) by glycerine, the ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25,
EDETATE SODIUM, preservative and deionized water add according to formula rate emulsifies pot, stirring and dissolving at 22 DEG C；
(2) olive oil is added after being heated to 75 DEG C, homogeneous 5min, 22min is incubated, is cooled to 55 DEG C；
(3) sodium cocoyl glycinate and Cocoamidopropyl betaine are added into emulsification pot according to formula rate, stirring is equal
It is even, 40 DEG C are cooled to, vacuum defoamation, that is, the amino acid cleansing breast is made.
The amino acid cleansing of embodiment 3 breast (III)
Formula is shown in Table 3.
Table 3
Preparation method：
(1) by glycerine, the ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25,
EDETATE SODIUM, preservative and deionized water add according to formula rate emulsifies pot, stirring and dissolving at 27 DEG C；
(2) olive oil is added after being heated to 85 DEG C, homogeneous 2min, 15min is incubated, is cooled to 65 DEG C；
(3) cocounut oil acyl potassium glutamate and Cocoamidopropyl betaine are added into emulsification pot according to formula rate, stirring is equal
It is even, 47 DEG C are cooled to, vacuum defoamation, that is, the amino acid cleansing breast is made.
The amino acid cleansing of embodiment 4 breast (IV)
Formula is shown in Table 4.
Table 4
Preparation method：
(1) by glycerine, the ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25,
EDETATE SODIUM, preservative and deionized water add according to formula rate emulsifies pot, stirring and dissolving at 20 DEG C；
(2) coconut oil is added after being heated to 70 DEG C, homogeneous 8min, 25min is incubated, is cooled to 52 DEG C；
(3) sodium cocoyl glutamate and coco betaine are added into emulsification pot according to formula rate, stirred, cooled
To 35 DEG C, vacuum defoamation, that is, the amino acid cleansing breast is made.
The amino acid cleansing of embodiment 5 breast (V)
Formula is shown in Table 5.
Table 5
Preparation method：
(1) by glycerine, acrylic acid/C10-30 alkylol acrylamide acid esters cross-linked polymer, EDETATE SODIUM, preservative and deionization
Water adds according to formula rate emulsifies pot, stirring and dissolving at 29 DEG C；
(2) Sweet Almond Oil is added after being heated to 90 DEG C, homogeneous 2min, 10min is incubated, is cooled to 68 DEG C；
(3) cocounut oil acyl disodium glutamate and sodium cocoamphoacetate are added into emulsification pot, stirring according to formula rate
Uniformly, 49 DEG C are cooled to, vacuum defoamation, that is, the amino acid cleansing breast is made.
Embodiment six amino acid mildy wash (VI)
Formula is shown in Table 6.
Table 6
Preparation method：
(1) by glycerine, acrylate/C10-30 alkylol acrylamide acid esters cross-linked polymer, EDETATE SODIUM, preservative and go from
Sub- water adds according to formula rate emulsifies pot, stirring and dissolving at 15 DEG C；
(2) hippophae rhamnoides fruit oil is added after being heated to 60 DEG C, homogeneous 10min, 30min is incubated, is cooled to 50 DEG C；
(3) cocoyl glutamic acid TEA salt and lauroylamidopropyl betaine are added into emulsification pot according to formula rate, stirred
Mix uniformly, be cooled to 30 DEG C, vacuum defoamation, that is, the amino acid cleansing breast be made.
The amino acid cleansing of embodiment 7 breast (VII)
Formula is shown in Table 7.
Table 7
Preparation method：
(1) by glycerine, hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers, EDETATE SODIUM, preservative and go
Ionized water adds according to formula rate emulsifies pot, stirring and dissolving at 30 DEG C；
(2) macadimia nut oil is added after being heated to 100 DEG C, homogeneous 1min, 5min is incubated, is cooled to 70 DEG C；
(3) sodium lauroyl glutamate and lauryl betaine are added into emulsification pot according to formula rate, stirred, cooled
To 50 DEG C, vacuum defoamation, that is, the amino acid cleansing breast is made.
Comparative example 1
Compared with Example 1, the formula of amino acid cleansing breast is not in addition to containing olive oil, and other preparation process are with implementing
Example 1 is identical.
Comparative example 2
Compared with Example 1, the formula of amino acid cleansing breast is not except containing ammonium acryloyldime-thyltaurate/docosyl alcohol
Outside the Methacrylate Crosspolymer of polyethers -25, other preparation process are same as Example 1.
Comparative example 3
Compared with Example 1, the formula of amino acid cleansing breast is shown in Table 8.
Table 8
Preparation method is same as Example 1.
Comparative example 4
Compared with Example 1, the formula of amino acid cleansing breast is shown in Table 9.
Table 9
Preparation method is same as Example 1.
The aqueous test of skin
The present invention is using embodiment and the mildy wash of comparative example preparation as comparison other, using Corneometer CM825
The capacitance of keratoderma, weighs the change of water content of stratum corneum before and after measurement use.
Subject totally 20, wherein women 15, male 5, age are 20-40 year, and average age is 28 years old.Subject
Wash hands forearm, sat quietly 30min under the humidity environment of setting, and 3 × 3cm is respectively chosen in the left and right forearm of subject2Just
Square Experimental Area, using left arm as embodiment and the test zone of the mildy wash of comparative example, the symmetrical region of right arm is as empty
White control, the moisture of each Test sites is detected with Corneometer CM825, is repeated 5 times, show that average value is remembered
Record.The calculation formula of skin hydration rate is：
After mildy wash 1 hour, the skin hydration rate result of subject is as shown in table 10.
Skin hydration rate of the table 10 using mildy wash after 1 hour
| Numbering | Skin hydration rate (%) |
| Embodiment 1 | 83.51 |
| Embodiment 2 | 81.74 |
| Embodiment 3 | 79.33 |
| Embodiment 4 | 77.94 |
| Embodiment 5 | 75.43 |
| Embodiment 6 | 75.37 |
| Embodiment 7 | 71.32 |
| Comparative example 1 | 22.27 |
| Comparative example 2 | 30.28 |
| Comparative example 3 | 35.21 |
| Comparative example 4 | 35.17 |
After embodiment 1-7 mildy wash 1 hour, the skin hydration rate of subject is above 70%, wherein working as amino
Sour mildy wash includes cocounut oil acyl glycine potassium 40%, Cocoamidopropyl betaine 10%, glycerine 10%, olive by mass percentage
Olive oil 20%, ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer 2% of docosyl alcohol polyethers -25, EDETATE SODIUM
0.05%th, preservative 0.5% and during deionized water 17.45%, the performance of keeping humidity of amino acid cleansing breast is optimal, and amino acid surface is lived
Property agent, amphoteric surfactant, vegetable fat and thickener match lower synergy herein, and the amino acid cleansing breast of preparation is being planted
The mass percent of thing grease provide not only effective cleaning power up to still having abundant foam when 20%, and clear
Grease is discharged while clean skin, the effect of having reached nourishing moisturizing.
Compared with Example 1, the mildy wash of comparative example 1 does not contain vegetable fat, using rear skin hydration rate only
22.27%, water content is very low；The mildy wash of comparative example 2 does not contain thickener, and vegetable fat is not wrapped in thickener and direct
Compounded with surfactant, defoaming phenomenon is obvious, and vegetable fat and surfactant can not play effective performance, skin
Hydration rate only 30.28%；The mildy wash formula rate of comparative example 3 and 4 is poor, and use feeling is poor, relatively low using rear skin hydration rate,
Wherein amount of thickener is too high in the mildy wash of comparative example 3, and quality is stiff, not easy to apply, thickener in the mildy wash of comparative example 4
Content is too low, and system is unstable.
After embodiment 1-3 and the mildy wash of comparative example 1, subject different time spaced points skin hydration rate such as
Shown in Fig. 1, after embodiment 1-3 mildy wash 8 hours, in the case where not smearing other skin care item, skin still has very
High water content, skin hydration rate have reached 40%, and after using the mildy wash of comparative example, skin hydration rate only 20%.
Erythrocyte hemolysis is tested
Erythrocyte hemolysis experiment is lagophthalmos stimulation test (Draize test) alternative, and general principle is to pass through survey
Determine hemoglobin stripping quantity and denaturation degrees carry out damage of the evaluating chemical product to ocular tissue's cell.Mainly pass through red blood cell in the world
Hemolytic experiment evaluates the excitant of cosmetics and its raw material to eye.
Mildy wash prepared by embodiment and comparative example is carried out erythrocyte hemolysis experiment by the present invention, and according to European alternative
The method of testing and grade scale (ECVAM.ECVAM DB-ALM of the erythrocyte hemolysis experiment of method authentication center (ECVAM):
INVITOX Protocol,Red blood cells test system.INVITOX No.37.Ispra.Italy:ECVAM,
1994) excitant of mildy wash is evaluated.Table 11 is ECVAM to the irritating grade scale of cosmetics.
The ECVAM of the table 11 irritating grade scale of cosmetics
Table 12 and Fig. 2 are the erythrocyte hemolysis experimental results of each sample.
The erythrocyte hemolysis experimental result of each sample of table 12
| Numbering | HC50(mg/L) | DI (%) | L/D | Evaluation |
| Embodiment 1 | 29191 | 99.84 | 162.38 | It is nonirritant |
| Embodiment 2 | 24471 | 99.35 | 146.31 | It is nonirritant |
| Embodiment 3 | 22465 | 99.17 | 126.53 | It is nonirritant |
| Embodiment 4 | 20480 | 98.82 | 107.25 | It is nonirritant |
| Embodiment 5 | 18731 | 98.73 | 109.72 | It is nonirritant |
| Embodiment 6 | 16335 | 98.44 | 125.94 | It is nonirritant |
| Embodiment 7 | 13128 | 98.27 | 113.59 | It is nonirritant |
| Comparative example 1 | 4027 | 92.27 | 43.64 | Microstimulation |
| Comparative example 2 | 4385 | 93.71 | 46.79 | Microstimulation |
| Comparative example 3 | 8606 | 94.29 | 71.27 | Microstimulation |
| Comparative example 4 | 8836 | 94.44 | 83.57 | Microstimulation |
As can be seen from Table 12, the mildy wash hemoglobin degenerative index (DI) that prepared by embodiment 1-7 is all higher than 98%, L/
D values are all higher than 100, in nonirritant；And the DI of comparative example 1-4 mildy wash only 92-94%, L/D value are less than 100, in aculea
Swash property.
The erythrocyte hemolysis experimental result of embodiment 1-3 and the mildy wash of comparative example 1 is as shown in Figure 2.Embodiment 1-3 ammonia
Base acid mildy wash is in not haemolysis under 0.2% concentration, and the mildy wash of comparative example 1 is then under 0.05% concentration in not haemolysis, explanation
The mildy wash of embodiment is using gently, and nonirritant, compared with not grease-contained amino acid cleansing breast, excitant significantly reduces.
Skin sense evaluation test
In order to evaluate the using effect of mildy wash of the present invention, using the mildy wash of embodiment and comparative example as test sample, choosing
40 subjects are taken to carry out skin sense evaluation test.Every kind of mildy wash uses 1 week, daily each 1 time of morning and evening, and subject was according to using
Feel to be scored in journey, scoring is using 5 points of systems, and 1 point is that effect is worst, and 5 points are best results.It the results are shown in Table 13.
The skin sense of table 13 evaluation statistics
| Numbering | Foaming abundancy degree | Washability | Wash rear tight feeling | Wash rear soft and smooth sense | Wash rear moisture feeling |
| Embodiment 1 | 4.9 | 4.8 | 4.8 | 4.9 | 5.0 |
| Embodiment 2 | 4.7 | 4.8 | 4.7 | 4.7 | 4.9 |
| Embodiment 3 | 4.6 | 4.7 | 4.6 | 4.7 | 4.8 |
| Embodiment 4 | 4.4 | 4.6 | 4.5 | 4.6 | 4.7 |
| Embodiment 5 | 4.3 | 4.5 | 4.2 | 4.5 | 4.6 |
| Embodiment 6 | 4.2 | 4.3 | 4.2 | 4.4 | 4.6 |
| Embodiment 7 | 4.2 | 4.2 | 4.1 | 4.4 | 4.5 |
| Comparative example 1 | 4.5 | 4.2 | 1.2 | 1.1 | 1.2 |
| Comparative example 2 | 1.5 | 3.1 | 1.6 | 1.4 | 1.3 |
| Comparative example 3 | 1.8 | 2.5 | 1.7 | 1.5 | 1.2 |
| Comparative example 4 | 1.7 | 2.4 | 1.7 | 1.9 | 1.4 |
Embodiment 1-7 mildy wash foaming abundancy, rinse well, moistened after use without dry and astringent tight feeling, skin slip；It is right
The mildy wash of ratio 1 does not contain vegetable fat, although with abundant foam, uses rear dry skin tight coarse, and
There is microstimulation, without moist effect；There is grease defoaming phenomenon in the mildy wash of comparative example 2, foam volume is low, and cleaning force is poor,
Punching does not wash clean, and tight feeling, harsh feeling be present using rear skin, lacks moistness；The formula of comparative example 3-4 mildy wash does not conform to
Reason, quality is hard or unstable, and use feeling is poor.
In summary, amino acid cleansing breast of the invention coordinates two using amino acid surfactant as primary surfactant
Property surfactant so that mildy wash property is gentle, cleaning force is moderate, added with significantly improved after vegetable fat surface live
Dry and astringent, the tight feeling that property agent is brought, are up to 83.51%, and vegetable fat is wrapped in into thickening using skin hydration rate after 1 hour
In agent, solves the problems, such as grease defoaming, the mildy wash foaming of preparation is abundant, and foam stabilizing ability is strong, not only with effective cleaning
Power, and grease is discharged while cleaning skin, there is the effect of nourishing moisturizing.
Applicant states that the present invention illustrates the method detailed of the present invention, but not office of the invention by above-described embodiment
It is limited to above-mentioned method detailed, that is, does not mean that the present invention has to rely on above-mentioned method detailed and could implemented.Art
Technical staff it will be clearly understood that any improvement in the present invention, equivalence replacement and auxiliary element to each raw material of product of the present invention
Addition, selection of concrete mode etc., within the scope of all falling within protection scope of the present invention and disclosing.
Claims (10)
1. a kind of amino acid cleansing breast, it is characterised in that the amino acid cleansing breast includes by mass percentage：
2. amino acid cleansing breast according to claim 1, it is characterised in that the amino acid surfactant includes cocounut oil
Acyl glycine potassium, sodium cocoyl glycinate, cocounut oil acyl potassium glutamate, sodium cocoyl glutamate, cocounut oil acyl disodium glutamate, cocounut oil
In acyl glutamic acid TEA salt or sodium lauroyl glutamate any one or at least two combination, the preferably sweet ammonia of cocounut oil acyl
Sour potassium；
Preferably, the amphoteric surfactant includes Cocoamidopropyl betaine, coco betaine, cocounut oil acyl both sexes base
In sodium acetate, lauroylamidopropyl betaine or lauryl betaine any one or at least two combination, preferably coconut palm
Oleamide CAB；
Preferably, the vegetable fat includes appointing in olive oil, coconut oil, Sweet Almond Oil, hippophae rhamnoides fruit oil or macadimia nut oil
Anticipate a kind of or at least two combinations；
Preferably, it is poly- to include the ammonium acryloyldime-thyltaurate/methacrylate of docosyl alcohol polyethers -25 crosslinking for the thickener
Compound, acrylic acid/C10-30 alkylol acrylamide acid esters cross-linked polymer, acrylate/C10-30 alkylol acrylamide acid esters cross-linked polymerics
In thing or hydroxy-ethyl acrylate/sodium acryloyldimethyl taurate copolymers any one or at least two combination, preferably
For ammonium acryloyldime-thyltaurate/Methacrylate Crosspolymer of docosyl alcohol polyethers -25.
3. amino acid cleansing breast according to claim 1 or 2, it is characterised in that the amino acid cleansing breast also includes sweet
In oil, EDETATE SODIUM or preservative any one or at least two combination；
Preferably, mass percent of the glycerine in the amino acid cleansing breast is 1-20%, preferably 10%；
Preferably, mass percent of the EDETATE SODIUM in the amino acid cleansing breast is 0.05%；
Preferably, mass percent of the preservative in the amino acid cleansing breast is 0.01-1%, preferably 0.5%.
4. the amino acid cleansing breast according to claim any one of 1-3, it is characterised in that the amino acid cleansing breast presses matter
Amount percentage includes：
5. the amino acid cleansing breast according to claim any one of 1-4, it is characterised in that the amino acid cleansing breast presses matter
Amount percentage includes：
6. the amino acid cleansing breast according to claim any one of 1-5, it is characterised in that the amino acid cleansing breast presses matter
Amount percentage includes：
A kind of 7. method of the amino acid cleansing breast prepared as described in claim any one of 1-6, it is characterised in that including following
Step：
(1) glycerine, thickener, EDETATE SODIUM, preservative and deionized water are added into emulsification pot according to formula rate, stirring is molten
Solution；
(2) vegetable fat is added after being heated to 60-100 DEG C, homogeneous, is cooled after constant temperature insulation；
(3) amino acid surfactant and amphoteric surfactant are added into emulsification pot according to formula rate, stirred, cooled
Vacuum defoamation afterwards, that is, the amino acid cleansing breast is made.
8. according to the method for claim 7, it is characterised in that the temperature of step (1) described stirring and dissolving is 15-30 DEG C,
Preferably 25 DEG C.
9. the method according to claim 7 or 8, it is characterised in that the temperature of step (2) described heating is 70-90 DEG C, excellent
Elect 80 DEG C as；
Preferably, the time of step (2) described homogeneous is 1-10min, preferably 1-5min, more preferably 3min；
Preferably, the time of step (2) described insulation is 5-30min, preferably 10-25min, more preferably 20min；
Preferably, the temperature of step (2) described cooling is 50-70 DEG C, preferably 60 DEG C.
10. according to the method described in claim any one of 7-9, it is characterised in that the temperature of step (3) described cooling is 30-
50 DEG C, preferably 45 DEG C.
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| CN201710919271.0A CN107569410A (en) | 2017-09-30 | 2017-09-30 | A kind of amino acid cleansing breast and preparation method thereof |
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| CN201710919271.0A CN107569410A (en) | 2017-09-30 | 2017-09-30 | A kind of amino acid cleansing breast and preparation method thereof |
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Family
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| CN201710919271.0A Pending CN107569410A (en) | 2017-09-30 | 2017-09-30 | A kind of amino acid cleansing breast and preparation method thereof |
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| CN108096048A (en) * | 2018-01-20 | 2018-06-01 | 广州康芙莱生物科技有限公司 | A kind of pure amino acid mildy wash with reproducibility and preparation method thereof and application method |
| CN108944112A (en) * | 2018-07-28 | 2018-12-07 | 黄智慧 | A kind of preparation method for exempting from alcohol fountain solution |
| CN109771334A (en) * | 2018-05-31 | 2019-05-21 | 菲朗生物科技(湖北)有限公司 | One kind repairing red mildy wash and preparation method thereof |
| CN110638679A (en) * | 2019-10-29 | 2020-01-03 | 广州市娇兰化妆品有限公司 | Amino acid cleansing cream compounded by amino acid potassium salt and amino acid sodium salt and preparation method thereof |
| CN111067853A (en) * | 2020-01-21 | 2020-04-28 | 广州睿新生物科技有限公司 | Mild and foamy skin cleaning composition and preparation method and application thereof |
| CN112516005A (en) * | 2020-11-13 | 2021-03-19 | 广州宏度精细化工有限公司 | Face cleaning composition and preparation method thereof |
| CN112716856A (en) * | 2021-01-26 | 2021-04-30 | 广州华厦生物制药有限公司 | Plant amino acid face washing lotion and processing technology thereof |
| CN113426368A (en) * | 2021-06-25 | 2021-09-24 | 江苏紫润化工有限公司 | High-resistance environment-friendly surfactant and preparation method thereof |
| CN114522118A (en) * | 2021-12-09 | 2022-05-24 | 诺斯贝尔化妆品股份有限公司 | Foaming type facial cleanser with warming effect and preparation method thereof |
| CN114588051A (en) * | 2021-09-03 | 2022-06-07 | 中山中研化妆品有限公司 | Amino acid cleansing bubble and preparation method thereof |
| CN115487086A (en) * | 2022-10-28 | 2022-12-20 | 上海康华时代生物医学科技有限公司 | Composition and cosmetic for improving skin moisturizing performance of follow-up skin care product |
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| CN108096048A (en) * | 2018-01-20 | 2018-06-01 | 广州康芙莱生物科技有限公司 | A kind of pure amino acid mildy wash with reproducibility and preparation method thereof and application method |
| CN109771334A (en) * | 2018-05-31 | 2019-05-21 | 菲朗生物科技(湖北)有限公司 | One kind repairing red mildy wash and preparation method thereof |
| CN108944112A (en) * | 2018-07-28 | 2018-12-07 | 黄智慧 | A kind of preparation method for exempting from alcohol fountain solution |
| CN110638679A (en) * | 2019-10-29 | 2020-01-03 | 广州市娇兰化妆品有限公司 | Amino acid cleansing cream compounded by amino acid potassium salt and amino acid sodium salt and preparation method thereof |
| CN110638679B (en) * | 2019-10-29 | 2022-08-16 | 广州市娇兰化妆品有限公司 | Amino acid cleansing cream compounded by amino acid potassium salt and amino acid sodium salt and preparation method thereof |
| CN111067853A (en) * | 2020-01-21 | 2020-04-28 | 广州睿新生物科技有限公司 | Mild and foamy skin cleaning composition and preparation method and application thereof |
| CN112516005B (en) * | 2020-11-13 | 2022-07-08 | 广州宏度精细化工有限公司 | Face cleaning composition and preparation method thereof |
| CN112516005A (en) * | 2020-11-13 | 2021-03-19 | 广州宏度精细化工有限公司 | Face cleaning composition and preparation method thereof |
| CN112716856A (en) * | 2021-01-26 | 2021-04-30 | 广州华厦生物制药有限公司 | Plant amino acid face washing lotion and processing technology thereof |
| CN113426368A (en) * | 2021-06-25 | 2021-09-24 | 江苏紫润化工有限公司 | High-resistance environment-friendly surfactant and preparation method thereof |
| CN114588051A (en) * | 2021-09-03 | 2022-06-07 | 中山中研化妆品有限公司 | Amino acid cleansing bubble and preparation method thereof |
| CN114588051B (en) * | 2021-09-03 | 2023-11-14 | 中山中研化妆品有限公司 | Amino acid cleansing foam and preparation method thereof |
| CN114522118A (en) * | 2021-12-09 | 2022-05-24 | 诺斯贝尔化妆品股份有限公司 | Foaming type facial cleanser with warming effect and preparation method thereof |
| CN115487086A (en) * | 2022-10-28 | 2022-12-20 | 上海康华时代生物医学科技有限公司 | Composition and cosmetic for improving skin moisturizing performance of follow-up skin care product |
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Address after: 510663 No.15, Kelin Road, Guangzhou Science City, Guangzhou high tech Industrial Development Zone, Guangdong Province Applicant after: Guangzhou Huanya cosmetics technology Co.,Ltd. Address before: No.18, Nanyun 1st Road, Guangzhou Development Zone, Guangdong 510000 Applicant before: GUANGZHOU HUANYA COSMETICS TECHNOLOGY Co.,Ltd. |
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