CN107530427A - 针对用于实体肿瘤的治疗的lhr的car t细胞疗法 - Google Patents

针对用于实体肿瘤的治疗的lhr的car t细胞疗法 Download PDF

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Publication number
CN107530427A
CN107530427A CN201680024480.2A CN201680024480A CN107530427A CN 107530427 A CN107530427 A CN 107530427A CN 201680024480 A CN201680024480 A CN 201680024480A CN 107530427 A CN107530427 A CN 107530427A
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Prior art keywords
lhr
seq
antibody
equivalent
amino acid
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CN201680024480.2A
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Chinese (zh)
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艾伦·L·爱泼斯坦
培生·胡
亚切克·K·宾斯奇
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University of Southern California USC
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University of Southern California USC
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CN201680024480.2A 2015-03-27 2016-03-25 针对用于实体肿瘤的治疗的lhr的car t细胞疗法 Pending CN107530427A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562139623P 2015-03-27 2015-03-27
US62/139,623 2015-03-27
PCT/US2016/024354 WO2016160618A2 (en) 2015-03-27 2016-03-25 Car t-cell therapy directed to lhr for the treatment of solid tumors

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CN107530427A true CN107530427A (zh) 2018-01-02

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US (3) US11136401B2 (enExample)
EP (1) EP3273994B1 (enExample)
JP (1) JP2018518152A (enExample)
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AU (1) AU2016243124A1 (enExample)
CA (1) CA2981142A1 (enExample)
ES (1) ES2904573T3 (enExample)
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JP2018518152A (ja) 2015-03-27 2018-07-12 ユニバーシティ オブ サザン カリフォルニア 充実性腫瘍を処置するためのｌｈｒに指向されたｃａｒ ｔ細胞治療
CA2987992A1 (en) 2015-06-04 2016-12-08 University Of Southern California Lym-1 and lym-2 targeted car cell immunotherapy
PL3484488T3 (pl) 2016-07-12 2024-02-05 Kite Pharma, Inc. Cząsteczki wiążące antygeny i sposoby ich stosowania
AU2017330423A1 (en) * 2016-09-23 2019-04-11 University Of Southern California Chimeric antigen receptors and compositions and methods of use thereof
BR112019011277A2 (pt) 2016-12-02 2019-10-22 University Of Southern California polinucleotídeo, sistema de expressão recombinante, vetor, polipeptídeo, célula recombinante, polipeptídeo de receptor imune sintético isolado ou heterodímero de polipeptídeo, célula efetora imune ou célula-tronco, população de células imunes ou efetoras, métodos de fabricação de uma célula efetora imune que expressa sir, de geração de uma população de células modificadas por rna, de fornecimento de imunidade antidoença e de tratamento ou prevenção de uma doença, composição, uso ou método, kit, e, sequência de aminoácidos.
SG10202109731YA (en) * 2017-03-13 2021-10-28 Poseida Therapeutics Inc Compositions and methods for selective elimination and replacement of hematopoietic stem cells
CN107354199A (zh) * 2017-07-04 2017-11-17 武汉波睿达生物科技有限公司 一种检测靶向cd30的cart细胞中car表达的荧光定量试剂盒
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