CN107496232A - A kind of herbaceous plant face cleaning toothpaste and its preparation method and application - Google Patents
A kind of herbaceous plant face cleaning toothpaste and its preparation method and application Download PDFInfo
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K8/00—Cosmetics or similar toiletry preparations
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- A61K8/04—Dispersions; Emulsions
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/805—Corresponding aspects not provided for by any of codes A61K2800/81 - A61K2800/95
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Abstract
The invention belongs to sanitary product technical field, specifically discloses a kind of herbaceous plant face cleaning toothpaste and its preparation method and application.The herbaceous plant face cleaning toothpaste, calculate in percentage by weight, comprising Chinese olive 1 2%, wrinkled giant hyssop 1 3%, peppermint 0.5 1.5%, elscholtiza 1 3%, sea-buckthorn 2 4%, radix glycyrrhizae 0.5 1.4%, calcium activated 30 50%, anion surfactant 1 3%, surplus is water.The face cleaning toothpaste of the present invention is prepared using supercritical carbon dioxide method for extracting and microemulsified, herbal effective ingredient can be kept to greatest extent, there is anti-inflammatory, hemostasis, eliminate swelling and pain, repair damaged skin, to solving oral hygiene and anti-treating dental ulcer, gingival swelling and pain, gingivitis, periodontitis, dispelling black tooth, xanthodont, den tal fluorosis, antipruritic anti-acne, eliminate acne and blackhead, good absorbing effect, it is quick, be advantageous to marketing.
Description
Technical field
The invention belongs to sanitary product technical field, specifically, be related to a kind of herbaceous plant face cleaning toothpaste and its
Preparation method and application.
Background technology
Toothpaste is a kind of common daily living article, for cleaning oral cavity, tooth-whitening or preventing odontopathy.Closely
Come, with the continuous improvement of people's living standards, health perception is also constantly strengthening, it is also proposed more for dental care products
High requirement.Consumer is not concerned only with oral cleaning effect in itself when choosing toothpaste, also favors in whitening, preventing and treating odontopathy or mouth
Other effects such as chamber disease.
At present, known medicated toothpaste added by a certain percentage from a few herbs extract and conventional toothpaste mostly and
Into however, existing Chinese medicine toothpaste washes one's face really very refrigerant but bad to skin, reason is as follows：First, the alkalescence of toothpaste is too big,
Skin can be made to be dried, and the people of skin sensitivity is also easy to cause allergy.Second, if had on the face after the people of acne used, acne
Trace is difficult to eliminate.3rd, toothpaste, which washes one's face, to cause dark sore to grow.
Therefore, those skilled in the art, which are necessary that exploitation is a kind of, has prevention and treatment canker sore, gingival swelling and pain, gum
Inflammation, periodontitis, dispel black tooth, be xanthodont, den tal fluorosis, antipruritic anti-acne, toothpaste and the mildy wash conjunction two for eliminating acne and blackhead effect
For one new product, for alleviating consumer's oral diseases, slowing down human communication pressure etc., there is important popularization
Meaning.
The content of the invention
The purpose of the present invention is exactly to overcome the shortcomings of existing Chinese medicine toothpaste, there is provided a kind of herbaceous plant face cleaning toothpaste
And its preparation method and application, it is separated from water that difficulty is big, hemostasis and pain-relieving anti-acne eliminates acne blackhead to solve existing Chinese medicine toothpaste
Less effective, toothpaste and mildy wash can not be combined into one the problem of causing home storage and tourism inconvenient to carry.
In order to solve the above-mentioned technical problem, the present invention is addressed by following technical proposals：
A kind of herbaceous plant face cleaning toothpaste, is calculated in percentage by weight, includes Chinese olive 1-2%, wrinkled giant hyssop 1-3%, peppermint
0.5-1.5%, elscholtiza 1-3%, sea-buckthorn 2-4%, radix glycyrrhizae 0.5-1.4%, calcium activated 30-50%, anion surfactant 1-
3%, surplus is water.
Preferably, calculating in percentage by weight, Chinese olive 1.5%, wrinkled giant hyssop 2%, peppermint 1%, elscholtiza 2%, sand are included
Spine 3%, radix glycyrrhizae 0.9%, calcium activated 39%, anion surfactant 2%, surplus are water.
Preferably, the anion surfactant is at least one of following substances：Fatty alcohol-ether sodium sulfate-
AES, alcohol ether carboxylate-AEC, methyl sodiosul foaliphatate.
Chinese olive, it is also known as " olive ", mild-natured, it is sweet, puckery, sour.Heat-clearing, relieving sore-throat, promote the production of body fluid, detoxify, relieve the pain.
Wrinkled giant hyssop is high calcium, high carotene food, per 100g tender leaf moisture contents 72g, protein 8.6g, fatty 1.7g, carbon water
Compound 10g, carrotene 6.38mg, vitamin B1 0.1mg, vitamin B2 0.38mg, niacin 1.2mg, vitamin
It is mainly estragole, lemon that C23mg, calcium 580mg, phosphorus 104mg, iron 28.5mg, herb, which contain in fragrant volatile oil 0.5%, oil,
Lemon alkene, australene and nopinene, p-cymene, linalool, I- cloves alkene etc., to a variety of pathogenic funguses, there is certain suppression
Make and use.
Peppermint is one of conventional Chinese medicine.It is pungent cool property sweating antipyretic medicine, controls the diseases such as gum swelling and pain.External application can control nerve
Bitterly, pruitus, fash and eczema etc..
There is antiviral, antibacterial, promoting blood circulation, the active component for changing the effects such as silt and desinsection containing many in Herba Moslae extract,
As Thymol, carvacrol, to P-cymene and 1,8 one cineoles etc. be suppress bacterium influenza virus main component,
With broad-spectrum antibacterial action.Eugenol, 2 one hexenoic aldehydes, linalool etc. have antibacterium, fungi and virus function.
Sea-buckthorn, fruit element have orientation osmosis, effective pox-dispelling function moisturizing factor that he extracts from fructus hippophae, passed through
Skin surface quickly absorbs, and orientation is directed to propionibacterium acnes, suppresses its infection, spreads unchecked, repairs impaired skin, recovering skin just
Normal renewal and the circulatory system.Seabuckthorn Oil has inhibitory action to after Oral Administration in Rats to collagen or the ADP platelet aggregation induced,
It is stronger to collagen-induced inhibition on platelet aggregation.
Radix glycyrrhizae, containing a variety of chemical compositions, main component has glycyrrhizic acid, liquiritin etc..The chemical combination isolated from radix glycyrrhizae
Thing have glycyrrhizin, enoxolone, liquiritin, isoliquiritin, neoliquriitin, neoisoliquiritin, glycyrrhizin, isoliquiritigenin and
The tens of kinds of compounds such as licoricidin, glycyrol, isoglycyrol, 7- methylcoumarins essence, umbelliferone.Substantial amounts of research table
Bright, glycyrrhizin and Flavonoid substances are most important physiological activators in radix glycyrrhizae, are primarily present within radix glycyrrhizae epiblem
Part.With anti-inflammatory, antiviral, antibacterial, the anti-metamorphosis of antiallergy.
Another object of the present invention additionally provides the preparation method of above-mentioned herbaceous plant face cleaning toothpaste, including step is as follows：
1) using supercritical carbon dioxide method for extracting to Chinese olive, wrinkled giant hyssop, peppermint, elscholtiza, sea-buckthorn, radix glycyrrhizae active ingredient
Extracted.
2) then supercritical extract, calcium activated, anion surfactant are well mixed, then into system slowly
Water is added dropwise and carries out microemulsified processing, obtains O/W type emulsions.
3) finally, toothpaste is qualified through examining, and packs, storage.
Preferably, supercritical carbon dioxide extracting condition described in step 1) is：Extracting pressure is 25-30MPa, extraction
Temperature is 30-40 DEG C, extraction time 90-150min, carbon dioxide flow rate 180-260L/h.
Preferably, microemulsified treatment temperature described in step 2) is 20-30 DEG C；The particle diameter of the O/W types emulsion is 8-
100nm。
Preferably, it be 1000~1500rpm/min that speed is mixed described in step 2), mixing time for 10~
15min。
Further object of the present invention is to provide above-mentioned herbaceous plant face cleaning toothpaste answering in mouth disease is prevented and treated
With.
Preferably, the mouth disease be canker sore, gingival swelling and pain, gingivitis, periodontitis, dispel black tooth, be xanthodont,
It is any in den tal fluorosis.
Last purpose of the invention is to provide above-mentioned herbaceous plant face cleaning toothpaste and is preventing and treating antipruritic anti-acne, elimination
Application in acne and blackhead.
Compared with prior art, the present invention can be obtained including following technique effect：
1) in herbaceous plant face cleaning toothpaste provided by the invention, include Chinese olive, licorice, play heat-clearing, relieving sore-throat,
Promote the production of body fluid, detoxify, relieving the pain, the effect of anti-inflammatory, antiviral, antibacterial, antiallergy resistance state, hard muscles and bones, long muscle, so as to reach permanent tooth
The effect of strong gum；There is hippophae rhamnoides pox-dispelling function moisturizing, orientation to be directed to propionibacterium acne, suppresses it and infects, be general
Excessively, impaired skin is repaired, recovers skin normally renewal and the circulatory system；Seabuckthorn Oil has the function that hemostasis, eliminates swelling and pain.It is fragrant
There is antiviral, antibacterial, antispastic, promoting blood circulation, the active component for changing the effects such as silt and desinsection containing many in Ru extracts；Peppermint carries
Take thing that there is clearing damp, scattered stasis detumescence, preventing and treating gingival swelling and pain, neuralgia, pruitus, fash and eczema.Calcium activated energy
Enamel density is improved, strengthens toothpaste cleaning capacity, adjusts toothpaste pH value, it is absorbed skin milder beneficial to skin；Cause
This, herbaceous plant face cleaning toothpaste provided by the invention is while solving oral hygiene, moreover it is possible to make the anti-treating dental ulcer of consumer,
Gingival swelling and pain, gingivitis, periodontitis, black tooth is dispelled, be xanthodont, den tal fluorosis, antipruritic anti-acne, eliminating acne and blackhead.Use this hair
Bright face cleaning toothpaste, quick, consumer is using 2-3 days with regard to that can see effect.In addition, consumer realizes oral cavity anti-aging
Effect.
2) herbaceous plant face cleaning toothpaste provided by the invention, realize toothpaste and be combined into one the packaging of body, family with mildy wash
Front yard stores time save space, easy to carry when consumer travels on official business；The pH value of the other face cleaning toothpaste is in 4.5-6.0, in weak
Acidity, allergic phenomena occur is not easy to the consumer of skin sensitivity.
3) when prepared by herbaceous plant face cleaning toothpaste provided by the invention using supercritical carbon dioxide method for extracting to Chinese olive,
Wrinkled giant hyssop, peppermint, elscholtiza, sea-buckthorn, the active ingredient of radix glycyrrhizae carry out extraction preparation, close to such as 30-40 DEG C of room temperature and carbon dioxide
Extracted under gas blanket, energy consumption is low, effectively prevents herbal oxidation and loss.Therefore, kept in extract
Whole compositions of medicinal plant, and higher boiling, low volatility, the material being easily pyrolyzed can be extracted below its boiling temperature
Out；Because overall process does not have to organic solvent, therefore extract absolutely not residual solvent, while extraction process is also prevent to human body
Murder by poisoning and pollution to environment；Carbon dioxide is a kind of inactive gas, and extraction process does not chemically react, and belongs to
Non-flammable gases, it is tasteless, odorless, nontoxic, therefore security is good.
4) handled when prepared by herbaceous plant face cleaning toothpaste provided by the invention using microemulsified, obtain O/W type emulsions, its boundary
Face tension force is low, and in 20mN.m-1 or so, the particle diameter of microemulsion is small, and particle diameter is between 8-100nm, and thermodynamic stability is good, when long
Between place will not be layered and be demulsified, when consumer uses the face cleaning toothpaste, to herbaceous plant extract good absorbing effect, take effect
It hurry up, be advantageous to marketing.
Certainly, implementing any product of the present invention must be not necessarily required to reach all the above technique effect simultaneously.
Embodiment
Following examples describe embodiments of the present invention in detail, and to the present invention, how application technology means solve whereby
Certainly technical problem and reach the implementation process of technical effect and can fully understand and implement according to this.
The specific embodiment of the invention uses HA220-50-06 type supercritical fluid extraction equipments；Jiangsu Province Nantong Huaan
It is super to face mist extraction Co., Ltd.
Embodiment 1
A kind of herbaceous plant face cleaning toothpaste, is calculated in percentage by weight, by Chinese olive 1.5%, wrinkled giant hyssop 2%, peppermint 1%,
Elscholtiza 2%, sea-buckthorn 3%, radix glycyrrhizae 0.9%, calcium activated 39%, alcohol ether carboxylate-AEC2%, surplus form for water.
The preparation method of the herbaceous plant face cleaning toothpaste of the present embodiment, step are as follows：
1) using supercritical carbon dioxide method for extracting to Chinese olive, wrinkled giant hyssop, peppermint, elscholtiza, sea-buckthorn, radix glycyrrhizae active ingredient
Extracted.
The supercritical carbon dioxide extracting condition is：Extracting pressure is 28-30MPa, and extraction temperature is 35-40 DEG C, extraction
Time is 90-120min, carbon dioxide flow rate 180-230L/h.
2) then supercritical extract, calcium activated, anion surfactant are well mixed, then into system slowly
Water is added dropwise and carries out microemulsified processing, obtains O/W type emulsions.
Microemulsified treatment temperature described in step 2) is 25-30 DEG C；The particle diameter of the O/W types emulsion is 8-100nm.
It is 1000~1200rpm/min, mixing time 12min that speed is mixed described in step 2).
3) finally, toothpaste is qualified through examining, and packs, storage.
Embodiment 2
The herbaceous plant face cleaning formulation of tooth-paste of the present embodiment is similar to Example 1, and it is differed only in：According to weight percent
Than calculating, by Chinese olive 1%, wrinkled giant hyssop 3%, peppermint 0.5%, elscholtiza 3%, sea-buckthorn 2%, radix glycyrrhizae 1.4%, calcium activated 30%, fat
Ether sulfate-AES 3%, surplus form for water.
The preparation method of the herbaceous plant face cleaning toothpaste of the present embodiment, similar to Example 1, it is differed only in：
Supercritical carbon dioxide extracting condition described in step 1) is：Extracting pressure is 25-28MPa, extraction temperature 30-
35 DEG C, extraction time 100-120min, carbon dioxide flow rate 200-260L/h.
Microemulsified treatment temperature described in step 2) is 20-25 DEG C；The particle diameter of the O/W types emulsion is 8-100nm.
It is 1200~1500rpm/min, mixing time 10min that speed is mixed described in step 2).
Embodiment 3
The herbaceous plant face cleaning formulation of tooth-paste of the present embodiment is similar to Example 1, and it is differed only in：According to weight percent
Than calculating, by Chinese olive 2%, wrinkled giant hyssop 1%, peppermint 1.5%, elscholtiza 1%, sea-buckthorn 4%, radix glycyrrhizae 0.5%, calcium activated 50%, fat
Sour methyl ester sulfonate 1%, surplus form for water.
The preparation method of the herbaceous plant face cleaning toothpaste of the present embodiment is similar to Example 1, and it is differed only in：
Supercritical carbon dioxide extracting condition described in step 1) is：Extracting pressure is 26-28MPa, extraction temperature 35-
38 DEG C, extraction time 120-140min, carbon dioxide flow rate 200-260L/h.
Microemulsified treatment temperature described in step 2) is 25-28 DEG C；The particle diameter of the O/W types emulsion is 8-100nm.
It is 1100~1300rpm/min, mixing time 15min that speed is mixed described in step 2).
Herbaceous plant face cleaning toothpaste carries out performance test obtained by the present embodiment 1-3, and its quality meets relevant national standard.Through
Clinical trial confirm, gained finished product can prevent and treat mouth disease for example canker sore, gingival swelling and pain, gingivitis, periodontitis,
Black tooth, xanthodont, den tal fluorosis are dispelled, antipruritic anti-acne, eliminates acne and blackhead, good absorbing effect is quick, and can deep clean tooth
Tooth keeps dental health.Clinical test is carried out by clinical test sample of the gained finished product of embodiment 1, it is specific as follows：
Clinical case：
Liu, female, 35 years old, canker sore often recurred, through repeatedly treatment easily recurrence, sooner or later using the face cleaning of embodiment 1
Toothpaste is cured after one week, and the toothpaste is continuing with after healing, is not recurred in 2 months.
Chen, man, 7 years old, sock, does not like to brush teeth, and tooth is damaged by worms swelling and pain, is taken other drugs and is had no effect, the morning and evening
Using the face cleaning toothpaste one week of embodiment 1, gingival swelling and pain starts progressively to take a turn for the better, and is continuing with one week, cures, continues to make after healing
With the toothpaste, do not recurred in 2 months.
Money, man, 56 years old, because gingivitis causes toothache for many years, obstinate, sooner or later using the face cleaning toothpaste of embodiment 1
One week, start progressively to take a turn for the better, be continuing with one week, cure.
Week certain, 67 years old multiple teeth is shaken, and suffers from periodontitis, bleeding gums, sooner or later using the face cleaning toothpaste of embodiment 1 early stage
Beginning in one week progressively takes a turn for the better, and is continuing with one week, cures.
Zhang, man, 38 years old, have smoke for a long time, history of having tea, most of tooth is aobvious yellow, a small number of tooth blackening, uses sooner or later
The face cleaning toothpaste of embodiment 1, after four weeks, tooth all bleaches.
Fourth, female, 20 years old, because Oil repellent is too high in drinking water, with den tal fluorosis, sooner or later using the face cleaning tooth of embodiment 1
Cream, start teeth whiter after two weeks, den tal fluorosis all bleaches after one month.
Lee, 20 years old, female, there are many small poxs on the face, working as mildy wash using the face cleaning toothpaste of embodiment 1 sooner or later uses one week
Small pox gradually decreases afterwards, is continuing with two weeks, cures.
Hu, 26 years old, female, have had blackhead on the face on many acne and nose, sooner or later using the face cleaning toothpaste of embodiment 1
When mildy wash use one week after, acne and blackhead gradually decrease, continue use two weeks after, acne and blackhead healing, continue after healing
Using the toothpaste when mildy wash use, do not recurred in half a year.
Comparative example 4
The herbaceous plant face cleaning formula of this comparative example is similar to Example 1, and it is differed only in：Sea-buckthorn 1%, activity
Calcium 20%, its preparation method is same as Example 1.
Clinical case：
Zhang, female, 35 years old, canker sore often recurred, through repeatedly treatment easily recurrence, sooner or later using comparative example 4
Face cleaning toothpaste progressively takes a turn for the better after 1 week, is cured after being continuing with one week.
Money, 20 years old, female, there are many small poxs on the face, sooner or later using the face cleaning toothpaste of comparative example 4 when mildy wash use
After one day, because face cleaning toothpaste acidity is too strong, occurs allergic phenomena on the face, stop using.
Comparative example 5
The herbaceous plant face cleaning formula of this comparative example is similar to Example 1, and it is differed only in：Chinese olive 0.5%, perfume
Ru 0.6%, calcium activated 60%, its preparation method is same as Example 1.
Clinical case：
Chen, multiple teeth is shaken within 67 years old, suffers from periodontitis, bleeding gums, sooner or later using the face cleaning of comparative example 5 early stage
Toothpaste progressively takes a turn for the better for two weeks, is continuing with not curing completely for one week, stops using.
Liu, 26 years old, female, have had blackhead on the face on many acne and nose, sooner or later using the face cleaning of comparative example 5
, because face cleaning toothpaste alkalescence is too strong, there is allergic phenomena, stopped using on the face after mildy wash uses one in toothpaste.
Herbaceous plant face cleaning toothpaste is while solving oral hygiene obtained by the present embodiment 1-3, moreover it is possible to prevents and treats consumer
Canker sore, gingival swelling and pain, gingivitis, periodontitis, black tooth is dispelled, be xanthodont, den tal fluorosis, antipruritic anti-acne, eliminating acne and blackhead.
Using herbaceous plant face cleaning toothpaste obtained by the present embodiment 1-3, quick, consumer is using 2-3 days with regard to that can see effect.In addition,
Consumer realizes the effect of oral cavity anti-aging.
Herbaceous plant face cleaning toothpaste obtained by the present embodiment 1-3, realize toothpaste and be combined into one the packaging of body, family with mildy wash
Front yard stores time save space, easy to carry when consumer travels on official business；The pH value of the other face cleaning toothpaste is in 4.5-6.0, in weak
Acidity, allergic phenomena occur is not easy to the consumer of skin sensitivity.
It should also be noted that, term " comprising ", "comprising" or its any other variant are intended to nonexcludability
Comprising, so that commodity or system including a series of elements not only include those key elements, but also including without clear and definite
The other element listed, or also include for this commodity or the intrinsic key element of system.In the feelings not limited more
Under condition, the key element that is limited by sentence "including a ...", it is not excluded that in the commodity including the key element or system also
Other identical element be present.
Some preferred embodiments of the present invention have shown and described in described above, but as previously described, it should be understood that the present invention
Be not limited to form disclosed herein, be not to be taken as the exclusion to other embodiment, and available for various other combinations,
Modification and environment, and above-mentioned teaching or the technology or knowledge of association area can be passed through in the scope of the invention is set forth herein
It is modified., then all should be in this hair and the change and change that those skilled in the art are carried out do not depart from the spirit and scope of the present invention
In the protection domain of bright appended claims.
Claims (10)
1. a kind of herbaceous plant face cleaning toothpaste, it is characterised in that calculate in percentage by weight, include Chinese olive 1-2%, wrinkled giant hyssop 1-
3%th, peppermint 0.5-1.5%, elscholtiza 1-3%, sea-buckthorn 2-4%, radix glycyrrhizae 0.5-1.4%, calcium activated 30-50%, anionic surface
Activating agent 1-3%, surplus are water.
2. herbaceous plant face cleaning toothpaste as claimed in claim 1, it is characterised in that calculate in percentage by weight, include green grass or young crops
Fruit 1.5%, wrinkled giant hyssop 2%, peppermint 1%, elscholtiza 2%, sea-buckthorn 3%, radix glycyrrhizae 0.9%, calcium activated 39%, anion surfactant
2%, surplus is water.
3. herbaceous plant face cleaning toothpaste as claimed in claim 1 or 2, it is characterised in that the anion surfactant is
At least one of following substances：Fatty alcohol-ether sodium sulfate-AES, alcohol ether carboxylate-AEC, methyl sodiosul foaliphatate.
4. the preparation method of the herbaceous plant face cleaning toothpaste described in any one of claims 1 to 3, it is characterised in that including step
It is as follows：
1) active ingredient of Chinese olive, wrinkled giant hyssop, peppermint, elscholtiza, sea-buckthorn, radix glycyrrhizae is carried out using supercritical carbon dioxide method for extracting
Extraction；
2) then supercritical extract, calcium activated, anion surfactant are well mixed, are then slowly added dropwise into system
Water carries out microemulsified processing, obtains O/W type emulsions；
3) finally, toothpaste is qualified through examining, and packs, storage.
5. the preparation method of herbaceous plant face cleaning toothpaste as claimed in claim 4, it is characterised in that surpass described in step 1) and face
Boundary's carbon dioxide abstraction condition is：Extracting pressure is 25-30MPa, and extraction temperature is 30-40 DEG C, extraction time 90-
150min, carbon dioxide flow rate 180-260L/h.
6. the preparation method of herbaceous plant face cleaning toothpaste as claimed in claim 4, it is characterised in that micro emulsion described in step 2)
It is 20-30 DEG C to change treatment temperature；The particle diameter of the O/W types emulsion is 8-100nm.
7. the preparation method of herbaceous plant face cleaning toothpaste as claimed in claim 4, it is characterised in that mixed described in step 2)
Mixing speed is 1000~1500rpm/min, and mixing time is 10~15min.
8. application of the herbaceous plant face cleaning toothpaste in mouth disease is prevented and treated described in any one of claim 1 to 7.
9. application as claimed in claim 8, it is characterised in that the mouth disease is canker sore, gingival swelling and pain, gum
Inflammation, periodontitis, black tooth is dispelled, be xanthodont, be any in den tal fluorosis.
10. the herbaceous plant face cleaning toothpaste described in any one of claim 1 to 7 is preventing and treating antipruritic anti-acne, is eliminating acne
With the application in blackhead.
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| CN201710758388.5A CN107496232A (en) | 2017-08-29 | 2017-08-29 | A kind of herbaceous plant face cleaning toothpaste and its preparation method and application |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108938473A (en) * | 2018-09-19 | 2018-12-07 | 上海纯元萃生物科技有限公司 | A kind of herbaceous toothpaste and its preparation method and application for preventing and treating oral inflammation |
| CN109758413A (en) * | 2019-03-26 | 2019-05-17 | 上海纯元萃生物科技有限公司 | A kind of herbal mouthwash and its low-temperature extraction technique |
| CN109806189A (en) * | 2019-03-27 | 2019-05-28 | 上海纯元萃生物科技有限公司 | A kind of low-temperature extraction technique and its outdoor toothpaste of preparation |
| CN109852481A (en) * | 2019-04-19 | 2019-06-07 | 上海纯元萃生物科技有限公司 | A kind of draft low-temperature extraction technique and its treatment periodontitis toothpaste of preparation |
| CN109985417A (en) * | 2019-04-19 | 2019-07-09 | 上海纯元萃生物科技有限公司 | A kind of draft low-temperature extraction technique and its pet toothpaste of preparation |
| CN111686051A (en) * | 2020-07-27 | 2020-09-22 | 浙江爱尚日用品有限公司 | Plant toothpaste for preventing and treating halitosis |
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| CN1079645A (en) * | 1993-05-20 | 1993-12-22 | 程宝义 | Edible toothpaste for children |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108938473A (en) * | 2018-09-19 | 2018-12-07 | 上海纯元萃生物科技有限公司 | A kind of herbaceous toothpaste and its preparation method and application for preventing and treating oral inflammation |
| CN109758413A (en) * | 2019-03-26 | 2019-05-17 | 上海纯元萃生物科技有限公司 | A kind of herbal mouthwash and its low-temperature extraction technique |
| CN109758413B (en) * | 2019-03-26 | 2021-09-24 | 上海纯元萃生物科技有限公司 | Herbal mouthwash and low-temperature extraction process thereof |
| CN109806189A (en) * | 2019-03-27 | 2019-05-28 | 上海纯元萃生物科技有限公司 | A kind of low-temperature extraction technique and its outdoor toothpaste of preparation |
| CN109852481A (en) * | 2019-04-19 | 2019-06-07 | 上海纯元萃生物科技有限公司 | A kind of draft low-temperature extraction technique and its treatment periodontitis toothpaste of preparation |
| CN109985417A (en) * | 2019-04-19 | 2019-07-09 | 上海纯元萃生物科技有限公司 | A kind of draft low-temperature extraction technique and its pet toothpaste of preparation |
| CN109985417B (en) * | 2019-04-19 | 2021-07-27 | 上海为止生物科技有限公司 | Herbal low-temperature extraction process and pet toothpaste prepared by same |
| CN109852481B (en) * | 2019-04-19 | 2022-02-18 | 上海为止生物科技有限公司 | Herbal low-temperature extraction process and toothpaste prepared by same and used for treating periodontitis |
| CN111686051A (en) * | 2020-07-27 | 2020-09-22 | 浙江爱尚日用品有限公司 | Plant toothpaste for preventing and treating halitosis |
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