CN107468899A - 一种补血丸及其制备方法 - Google Patents

一种补血丸及其制备方法 Download PDF

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CN107468899A
CN107468899A CN201710877224.4A CN201710877224A CN107468899A CN 107468899 A CN107468899 A CN 107468899A CN 201710877224 A CN201710877224 A CN 201710877224A CN 107468899 A CN107468899 A CN 107468899A
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陈家胜
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Abstract

本发明提供一种补血丸，它由如下重量份数的原料制备得到：赤小豆20‑30份、枸杞子10‑20份、龙眼肉10‑18份、覆盆子10‑25份、桔梗15‑25份、黄精8‑12份、向日葵花粉2‑5份，并采用了相应的制备方法，本发明具有补血功效。

Description

一种补血丸及其制备方法
技术领域
本发明属于保健食品技术领域，具体涉及一种补血丸及其制备方法。
背景技术
我国血液病学家认为在我国海平面地区，成年男性Hb<120g/L，成年女性(非妊娠)Hb<110g/L，孕妇Hb<100g/L就有贫血。1972年WHO制订的诊断标准认为在海平面地区Hb低于下述水平诊断为贫血：6个月到<6岁儿童110g/L，6～14岁儿童120g/L，成年男性130g/L，成年女性120g/L，孕妇110g/L。应注意，久居高原地区居民的血红蛋白正常值较海平面居民为高；在妊娠、低蛋白血症、充血性心力衰竭、脾肿大及巨球蛋白血症时，血浆容量增加，此时即使红细胞容量是正常的，但因血液被稀释，血红蛋白浓度降低，容易被误诊为贫血；在脱水或失血等循环血容量减少时，由于血液浓缩，即使红细胞容量偏低，但因血红蛋白浓度增高，贫血容易漏诊。目前缺乏治疗贫血的保健食品。
发明内容
发明目的：为了解决上述问题，本发明提供了一种补血丸及其制备方法。
一种补血丸，它由如下重量份数的原料制备得到：赤小豆20-30份、枸杞子10-20份、龙眼肉10-18份、覆盆子10-25份、桔梗15-25份、黄精8-12份、向日葵花粉2-5份。
所述补血丸，它由如下重量份数的原料制备得到：赤小豆25份、枸杞子15份、龙眼肉14份、覆盆子18份、桔梗20份、黄精10份、向日葵花粉4份。
所述补血丸，制备方法包括如下步骤：取上述除向日葵花粉外中药，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加向日葵花粉、辅料制成丸剂。
所述补血丸在制备补血保健食品中的应用。
有益效果：本发明中赤小豆清热退黄、解毒排脓，枸杞子滋补肝肾为君药，龙眼肉益气补血，覆盆子益肾固精缩尿，养肝明目为臣药，桔梗、黄精、向日葵花粉为佐使药，全方具有补血作用。
具体实施方式
以下通过实施例形式对本发明的上述内容再作进一步的详细说明，但不应将此理解为本发明上述主题的范围仅限于以下的实施例，凡基于本发明上述内容所实现的技术均属于本发明的范围。
实施例1：取赤小豆20份、枸杞子20份、龙眼肉10份、覆盆子25份、桔梗15份、黄精12份、向日葵花粉2份，制备方法包括如下步骤：取上述除向日葵花粉外中药，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加向日葵花粉、辅料制成丸剂。
实施例2：取赤小豆30份、枸杞子10份、龙眼肉18份、覆盆子10份、桔梗25份、黄精8份、向日葵花粉5份，制备方法包括如下步骤：取上述除向日葵花粉外中药，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加向日葵花粉、辅料制成丸剂。
实施例3：取赤小豆25份、枸杞子15份、龙眼肉14份、覆盆子18份、桔梗20份、黄精10份、向日葵花粉4份，制备方法包括如下步骤：取上述除向日葵花粉外中药，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加向日葵花粉、辅料制成丸剂。
实施例4：本发明对失血小鼠的治疗作用
试验药品：按照上述实施例3的方法制备试验药品。
方法：对失血小鼠的影响ICR小鼠40只，♀♂各半，均分成4组(n＝10)。除生理盐水组外，其它组每只小鼠从眼眶静脉放血0.5ml，24h后再取血测全部各组指标，然后连续灌胃给药1周，末次给药1h后，从眼眶静脉丛取血用F-800全血小板分析仪测上述指标。
本发明对因失血所致红细胞减少的治疗作用
与模型组比较：*p<0.05**p<0.01
结果表明，放血小鼠经服用本发明治疗7天后，2个给药组分别于模型组比较，其红细胞显著高于模型组，接近生理盐水组，说明本发明具有补血作用。

Claims (4)

1.一种补血丸，其特征在于，它由如下重量份数的原料制备得到：赤小豆20-30份、枸杞子10-20份、龙眼肉10-18份、覆盆子10-25份、桔梗15-25份、黄精8-12份、向日葵花粉2-5份。
2.如权利要求1所述补血丸，其特征在于，它由如下重量份数的原料制备得到：赤小豆25份、枸杞子15份、龙眼肉14份、覆盆子18份、桔梗20份、黄精10份、向日葵花粉4份。
3.如权利要求1所述补血丸，其特征在于，制备方法包括如下步骤：取上述除向日葵花粉外中药，加药材10倍重量的水，浸泡0.5h，煎煮1小时，过滤，药渣再加入药材8倍重量的水，煎煮1小时，药液滤出，合并两次煎煮液，减压浓缩至60℃相对密度为1.05，加乙醇使含醇量的体积百分比达75％，搅拌，静置，过滤，滤液减压浓缩至65℃时相对密度为1.25，并回收乙醇，得浓缩液，将浓缩液喷雾干燥，喷雾干燥条件为：进风温度为100℃，出风温度为90℃，物料温度为70℃，雾化压力为0.2兆帕，喷雾速度为10ml/s，添加向日葵花粉、辅料制成丸剂。
4.如权利要求1所述补血丸在制备补血保健食品中的应用。
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CN108514111A (zh) * 2018-03-05 2018-09-11 安徽省霍山县福康石斛开发有限公司 一种养血柔肝石斛糕的制备方法
CN110638936A (zh) * 2019-10-11 2020-01-03 宣城华科宣木瓜生物科技有限公司 一种宣木瓜补血丸及其制备方法

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CN105395850A (zh) * 2015-11-29 2016-03-16 殷志杰 补血兼补气的药物及保健品
CN106309918A (zh) * 2016-09-30 2017-01-11 四川雄者酒业有限公司 一种补气养血的中药组合物及其制备方法和应用
CN106942745A (zh) * 2017-04-26 2017-07-14 云南净血王生物科技有限公司 一种补气血粉状食品及制作工艺

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CN110638936A (zh) * 2019-10-11 2020-01-03 宣城华科宣木瓜生物科技有限公司 一种宣木瓜补血丸及其制备方法

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