CN107468852A - 一种治疗酒渣鼻的汤剂药物及其制备方法 - Google Patents

一种治疗酒渣鼻的汤剂药物及其制备方法 Download PDF

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CN107468852A
CN107468852A CN201710797211.6A CN201710797211A CN107468852A CN 107468852 A CN107468852 A CN 107468852A CN 201710797211 A CN201710797211 A CN 201710797211A CN 107468852 A CN107468852 A CN 107468852A
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罗兴贵
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Chengdu Xing More Biotechnology LLC
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Abstract

本发明属于中药制剂领域，目的是根据中医治疗酒渣鼻的认识机理而提供的一种治疗酒渣鼻的汤剂药物，所述药物的各个组分及其质量份比如下：生地黄10～38g、墨旱莲10～35g、栀子10～25g、黄连3～7g、夏枯草6～16g、赤芍4～12g、牡丹皮8～16g、鸡血藤9～16g、丹参5～16g、黄芩3～12g、桑白皮9～16g、大黄(酒炒)3～16g、香附5～12g、蒲公英15～55g、玫瑰花2～8g、红花5～15g、鸡骨草15～35g、甘草3～15g，本发明提供的药物是一个很好的中药组方。

Description

一种治疗酒渣鼻的汤剂药物及其制备方法
技术领域
本发明属于中药制剂领域，具体涉及一种治疗酒渣鼻的汤剂药物，特别是供酒渣鼻患者使用的汤剂药物及其制备方法的领域。
背景技术
医者认为：酒渣鼻又称酒糟鼻、玫瑰痤疮，其确切病因不清楚，多种因素都有可能诱发或加重疾病，包括局部血管舒缩神经失调，毛囊虫及局部反复感染，实用辛辣食物、饮酒、冷热刺激、精神紧张、情绪激动、内分泌功能障碍等。酒渣鼻多发生在鼻准头及鼻两侧，以皮肤潮红、丘疹、脓疱，甚至鼻头增大变厚为特征的一种酒渣鼻，本病常并发脂溢性皮炎。早期鼻部出现红色的小丘疹、丘疱疹和脓疱，鼻部毛细血管充血严重，肉眼可见明显树枝状的毛细血管分支，晚期出现鼻赘，鼻子上出现大小不等的结节和凹凸不平的增生，鼻子肥大不适，严重影响患者的形象美观和心理健康。目前西医多以抗生素控制炎症，并对于患病两个月以上的患者做酒渣鼻划痕手术，但手术副作用大，且费用较高。
那么，就如何找到一种可有效治疗酒渣鼻的中药组合物，是本领域技术人员亟待要解决的问题。
发明内容
随着我国中医中药学的不断发展，在治疗酒渣鼻上，人们逐渐意识到了中医治疗酒渣鼻的优点，且在治疗过程中疗效好、见效快、毒副作用小等优势，针对现有西医治疗酒渣鼻的现状，本发明的目的是在于提供一种治疗酒渣鼻的汤剂药物，以解决酒渣鼻患者早日恢复健康的问题。该药物是以常见的中药为原料，通过选择合理的药物及其质量份比，可有效治疗上述酒渣鼻。
为达到上述发明的目的，本发明所采用的技术方案为：提供一种治疗酒渣鼻的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄10～38g、墨旱莲10～35g、栀子10～25g、黄连3～7g、夏枯草6～16g、赤芍4～12g、牡丹皮8～16g、鸡血藤9～16g、丹参5～16g、黄芩3～12g、桑白皮9～16g、大黄 (酒炒)3～16g、香附5～12g、蒲公英15～55g、玫瑰花2～8g、红花5～15g、鸡骨草15～35g、甘草3～15g。
一种治疗酒渣鼻的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄12～34g、墨旱莲12～32g、栀子12～22g、黄连4～6g、夏枯草8～14g、赤芍5～11g、牡丹皮9～14g、鸡血藤10～14g、丹参6～14g、黄芩5～11g、桑白皮10～14g、大黄 (酒炒) 6～14g、香附6～11g、蒲公英18～48g、玫瑰花3～7g、红花6～13g、鸡骨草18～32g、甘草6～13g。
一种治疗酒渣鼻的汤剂药物及其制备方法，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄30g、墨旱莲28g、栀子20g、黄连5g、夏枯草12g、赤芍10g、牡丹皮12g、鸡血藤12g、丹参12g、黄芩10g、桑白皮12g、大黄 (酒炒) 12g、香附10g、蒲公英42g、玫瑰花6g、红花12g、鸡骨草26g、甘草12g。
一种治疗酒渣鼻的汤剂药物及其制备方法，其特征在于，所述方法包括如下步骤制备而成：
A、将上述原料中药拣去杂质和粉尘后，按照质量份比共粉碎成粗粒状包煎；
B、将包好的原料中药放入冷开水中浸泡半小时，然后再将浸泡好的药物放入砂锅内，注入过药60mm的冷开水进行第一次煎煮60分钟，滤取药液后，再次注入过药55mm的微温开水进行第二次煎煮50分钟，滤取药液后，将二次药液混合浓缩成50%的中药液540毫升，分装密封即可。
一种治疗酒渣鼻的汤剂药物及其制备方法，其特征在于，所述服用方法为：将制备好的中药液以一天服用，早中晚各服一次，给药量180毫升/次，直接服用。15天为一个疗程，治疗2～3个疗程，症状全部消失，病获痊愈。
本发明组方中的各原料中药在中国药典、中国辞典以及中华本草中均有详细的记载。本发明选用其中最常见的中药为原料，充分发挥各组分的药理功效：
生地黄，性味：味甘、苦、性寒，具有清热、凉血之功效，用于治疗温热病热入营血、壮热神昏、口干舌绛；
墨旱莲，性味：味甘、酸、性凉，具有补益肝肾、凉血止血之功效，用于治疗肝肾不足、头晕目眩、须发早白、吐血、咯血、衄血、便血、血痢、崩、漏、外伤出血；
栀子，性味：苦，寒，具有清热、泻火、凉血之功效，用于治疗热病虚烦不眠、黄疸、淋病、消渴、目赤、咽痛、吐血、衄血、血痢、尿血、热毒疮疡、扭伤肿痛；
黄连，性味：性寒、味苦，具有泻火、燥湿、解毒、杀虫之功效，用于治疗时行热毒、伤寒、热盛心烦、痞满呕逆、菌痢、热泻腹痛、肺结按、吐、衄、下血、消渴、疳积、蛔虫病、百日咳、咽喉肿痛、火眼、口疮、痈疽疮毒、湿疹、汤火烫伤；
夏枯草，性味：味苦、辛、性寒，具有清肝明目、散结解毒之功效，用于治疗目亦羞明、目珠疼痛、头痛眩晕、耳鸣、瘰疬、瘿瘤、乳痈、痄腮、痈疖肿毒、急慢性肝炎、高血压病；
赤芍，性味：苦、微寒，具有清热凉血、活血祛瘀之功效，用于治疗温毒发斑、吐血衄血、肠风下血、目赤肿痛、痈肿疮疡、闭经、痛经、崩带淋浊、瘀滞胁痛、疝瘕积聚、跌扑损伤；
牡丹皮，性味：辛苦、凉、微寒，具有清热、活血散瘀之功效，用于治疗温热病热入血分、发斑、吐衄、热泪盈眶病菌后期热伏阴分发热、阴虚骨蒸潮热、血滞经闭、痛经、痈肿疮毒、跌扑伤痛、风湿热痹；
鸡血藤，性味：苦、甘、温，具有活血补血、调经止痛、舒筋活络之功效，用于治疗月经不调、痛经、经闭、风湿痹痛、麻木瘫痪、血虚萎黄；
丹参，性味：味苦、性微寒，具有活血祛瘀、调经止痛、养血安神、凉血消痈之功效，用于治疗妇女月经不调、痛经、经闭、产后瘀滞腹痛、心腹疼痛、癥瘕积聚、热痹肿痛、跌打损伤、热入营血、烦躁不安、心烦失眠、痈疮肿毒；
黄芩，性味：味苦、性寒，具有清热泻火、燥湿解毒、止血、安胎之功效，用于治疗肺热咳嗽、热病高热神昏、肝火头痛、目赤肿痛、湿热黄疸、泻痢、热淋、吐衄血、崩漏、胎热不安、痈肿疔疮；
桑白皮，性味：味甘、辛、性寒，具有泻肺平喘、利水消肿之功效，用于治疗肺热喘咳痰、水饮停肺、胀满喘急、水肿、脚气、小便不利；
大黄 (酒炒)，性味：苦、性寒，具有攻积滞、清湿热、泻火、凉血、祛瘀、解毒之功效，用于治疗实热便秘、热结胸痞、湿热 泻痢、黄疸、淋病、水肿腹满、小便不利、目赤、咽喉肿痛、口舌生疮、胃热呕吐、吐血、咯血、衄血、便血、尿血、蓄血、经闭、产后瘀滞腹痛、癥瘕积聚、跌打损伤、热毒痈疡、丹毒、烫伤等症；
香附，性味：味辛、微寒，无毒，具有理气解郁、调经止痛、安胎之功效，用于治疗胁肋胀痛、乳房胀育、疝气疼痛、月经不调、脘腹痞满疼痛、嗳气吞酸，呕恶、经行腹痛、崩漏带下、胎动不安；
蒲公英，性味：苦甘、寒，具有清热解毒、利尿散结之功效，用于治疗急性乳腺炎、淋巴腺炎、瘰疬、疔毒疮肿、急性结膜炎、感冒发热、急性扁桃体炎、急性支气管炎、胃炎、肝炎、胆囊炎、尿路感染；
玫瑰花，性味：甘、微苦、温，具有行气解郁、和血、止痛之功效，用于治疗肝胃气痛、食少呕恶、月经不调、跌扑伤痛；
红花，性味：味辛、性温，具有活血能经、祛瘀止痛之功效，用于治疗经闭、痛经、产后瘀阻腹痛、胞痹心痛症瘕积聚、跌打损伤、关节疼痛、中风偏竣、斑疹等症；
鸡骨草，性味：味甘、微苦、性凉，具有利湿退黄、清热解毒、疏肝止痛之功效，用于治疗湿热黄疽、胁肋不舒、胃脘胀痛、乳痈肿痛；
甘草，性味：甘、平，具有益气补中、缓急止痛、润肺止咳、泻火解毒、调和诸药之功效，用于治疗倦怠食少、肌瘦面黄、心悸气短、腹痛便溏、四肢挛急疼痛、脏躁、咳嗽气喘、咽喉肿痛、痈疮肿痛、小儿胎毒及药物、食物中毒。
本发明药物是基于中医治疗酒渣鼻的原则，从依据酒渣鼻的病理机制及药理作用认为：就酒渣鼻，本发明所提供的药物中的各原料中药药效共奏，对上述疾病有很好的治疗效果。
具体实施方式
本发明就是针对上述酒渣鼻的治疗而提出的一种中药配方，采用该配方制备的药物药效好，见效快，是一个很好的中药组方，特别适合临床使用。下面结合本发明的具体实施方式作进一步详细的描述：
实施例1：
一种治疗酒渣鼻的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄30g、墨旱莲28g、栀子20g、黄连5g、夏枯草12g、赤芍10g、牡丹皮12g、鸡血藤12g、丹参12g、黄芩10g、桑白皮12g、大黄 (酒炒) 12g、香附10g、蒲公英42g、玫瑰花6g、红花12g、鸡骨草26g、甘草12g。
实施例2：
一种治疗酒渣鼻的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄34g、墨旱莲32g、栀子22g、黄连6g、夏枯草14g、赤芍11g、牡丹皮14g、鸡血藤14g、丹参14g、黄芩11g、桑白皮14g、大黄 (酒炒) 14g、香附11g、蒲公英48g、玫瑰花7g、红花13g、鸡骨草32g、甘草13g。
实施例3：
一种治疗酒渣鼻的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄38g、墨旱莲35g、栀子25g、黄连7g、夏枯草16g、赤芍12g、牡丹皮16g、鸡血藤16g、丹参16g、黄芩12g、桑白皮16g、大黄 (酒炒) 16g、香附12g、蒲公英55g、玫瑰花8g、红花15g、鸡骨草35g、甘草15g。
疗效判定标准:根据《中医病证诊断疗效标准》
其典型病例如下：
经临床诊断治疗酒渣鼻患者共1355例，年龄为33岁以上的745例，只有610例为33岁以下。1355例患者中痊愈的735例，有效的525例，无效的95例。总有效率达93%。

Claims (3)

1.一种治疗酒渣鼻的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄10～38g、墨旱莲10～35g、栀子10～25g、黄连3～7g、夏枯草6～16g、赤芍4～12g、牡丹皮8～16g、鸡血藤9～16g、丹参5～16g、黄芩3～12g、桑白皮9～16g、大黄 (酒炒)3～16g、香附5～12g、蒲公英15～55g、玫瑰花2～8g、红花5～15g、鸡骨草15～35g、甘草3～15g。
2.根据权利要求1所述的治疗酒渣鼻的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄12～34g、墨旱莲12～32g、栀子12～22g、黄连4～6g、夏枯草8～14g、赤芍5～11g、牡丹皮9～14g、鸡血藤10～14g、丹参6～14g、黄芩5～11g、桑白皮10～14g、大黄 (酒炒) 6～14g、香附6～11g、蒲公英18～48g、玫瑰花3～7g、红花6～13g、鸡骨草18～32g、甘草6～13g。
3.根据权利要求1至2所述的治疗酒渣鼻的汤剂药物，其特征在于，所述药物的各个组分及其质量份比如下所示：
生地黄30g、墨旱莲28g、栀子20g、黄连5g、夏枯草12g、赤芍10g、牡丹皮12g、鸡血藤12g、丹参12g、黄芩10g、桑白皮12g、大黄 (酒炒) 12g、香附10g、蒲公英42g、玫瑰花6g、红花12g、鸡骨草26g、甘草12g。
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