CN107468625A - A kind of EGF for medical cosmetology imports liquid - Google Patents
A kind of EGF for medical cosmetology imports liquid Download PDFInfo
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- CN107468625A CN107468625A CN201610401832.3A CN201610401832A CN107468625A CN 107468625 A CN107468625 A CN 107468625A CN 201610401832 A CN201610401832 A CN 201610401832A CN 107468625 A CN107468625 A CN 107468625A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
- A61K2800/882—Mixing prior to application
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- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
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- Gerontology & Geriatric Medicine (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The invention belongs to care tool technical field, more particularly to a kind of EGF for medical cosmetology to import liquid.The invention discloses a kind of EGF for medical cosmetology to import liquid, it is characterised in that including following components and percentage by weight：Niacinamide:1 5%, xanthans:0.1 0.15%, Sodium Polyacrylate:0.2 0.25%, hyaluronic acid:0.05 0.3%, artemia extract:0.5 2%, remaining is water.The beneficial effects of the invention are as follows：EGF freeze-dried powders can be dissolved well, can mutually be cooperateed with EGF effect, reach the effect of multiple skin care, can effectively help absorbing for EGF, itself can also effectively strengthen EGF cosmetology effect.
Description
Technical field
The invention belongs to care tool technical field, more particularly to a kind of EGF for medical cosmetology to import liquid.
Background technology
It is current on the market for medical cosmetology by many makeups product, but such makeups product are being constantly present the problem of more during use.At present, experimental study shows hEGF（Epidermal
Growth Factor, EGF）It is a kind of small peptide of human body cell secretion, is made up of 53 amino acid residues, the dalton of molecular weight 6201, the disulfide bond that intramolecular is made up of 6 cysteines, form 3 intramolecular ring type structures, forms receptorbinding region necessary to bioactivity.EGF can stimulate skin histology, cornea and the growth and breeding of tracheal epithelial tissue, accelerate the reparation of cornea, the superficial wound such as skin, promote application on human skin epithelial cell, corneal epithelial cell and mammalian epithelial cell growth, strengthen the protein of epidermal cell cell, DNA and RNA synthesis and metabolism.
EGF plays physiological action by being combined with EGF receptor on cell membrane.Research shows：All contain EGF receptor, wherein epidermal cell content highest on the cell membrane of the various kinds of cell such as epidermal cell, fibroblast, endothelial cell and smooth muscle cell.EGF is combined with the EGF receptor on cell membrane, is passed the signal along to cell interior by enzyme cascade, is promoted the expression of the albumen associated with cell division, so as to promote cell growth to breed, accelerates cell metabolism.The combination of EGF and cell receptor has the sensitiveness of height, only needs the EGF of denier and can promote cell that above-mentioned biochemical reactions occur.
EGF has extensive biological effect, can strongly promote various epidermal tissues to grow, and medically oneself is used for the treatment of burn and scald, ulcer, all kinds of wounds and corneal injury etc..EGF can also promote the metabolism of normal epidermis cell, and whitening, crease-resistant, anti-aging can be haveed the function that by being added in cosmetics and skincare product.
Restructuring EGF is protein product, and to keep its bioactivity, the form of freeze-dried powder is typically all made by manufacturer.Wiped so needing and forming the liquid that can be smeared after a kind of importing liquid can dissolve to EGF.
The content of the invention
It is an object of the invention to solve the problems, such as techniques discussed above, there is provided one kind can dissolve to EGF freeze-dried powders well, can mutually it be cooperateed with EGF effect, reach the effect of multiple skin care, absorbing for EGF can effectively be helped, the EGF for medical cosmetology that itself can also effectively strengthen EGF cosmetology effect imports liquid, and its technical scheme is as follows：
A kind of EGF for medical cosmetology imports liquid, it is characterised in that including following components and percentage by weight：
Niacinamide: 1-5%,
Xanthans:0.1-0.15%,
Sodium Polyacrylate:0.2-0.25%,
Hyaluronic acid:0.05-0.3%,
Artemia extract:0.5-2%, remaining is water.
Preferred embodiment is, in addition to dipotassium glycyrrhizinate：0.05-0.3%, Aloe Vera Gel：1-10%.
Liquid is imported provided by the present invention for the EGF of medical cosmetology, when in use, it is only necessary to importing liquid is poured into EGF freeze-dried powders, then carries out rocking and uniformly enters to use.It can be applied in face and body.
Add dipotassium glycyrrhizinate：0.05-0.3%, Aloe Vera Gel：1-10%, it can cause this product that there is different functions, whitening and anti-aging function.
EGF mainly has in purposes cosmetically：
1st, tender skin effect
EGF can irritate various cells such as corneal epithelium and endothelial cell, epidermis, corium confluent monolayer cells (such as fibroblast), mammary gland alveolus and the interstitial cell of ectoderm and endodermal origin, make its proliferation apoptosis, accelerate metabolism, reach the effect of tender skin.
2nd, skin care
EGF can promote the biosynthesis of DNA, RNA and functional protein, can promote the synthesis (such as hyaluronic acid, elastomer albumen) of extracellular macromolecular, increase moisture content of skin, and then increase skin elasticity, Glycerin.
3rd, smooth away wrinkles
EGF, which promotes cytotrophy material to be transported to from extracellular active, into the cell, increases intracellular nutrition.Promote the functional moleculars such as corium confluent monolayer cells secretion synthesis collagenous fibres, polysaccharide, glycoprotein, make that subcutaneous dermal tissue is full, muscle fibre marshalling is close, so as to reduce and smooth away wrinkles.
4th, wound is repaired
Epidermal cell is irritated by being combined with EGF receptor（Epithelial cell including Various Tissues source, various interstitial cells）Into CDC, some interior critical function gene activations of active cell, expression, secretion biological activity protein etc..It is in the linear alignment, the growth of epidermal cell fast regular and timely flap coverage to promote collagenous fibres.After significantly accelerated beauty, cosmetic operation and the wound healing such as other skin traumas, and surface of a wound flat smooth is kept, abnormal pigmentary deposit on the skin trace is reduced or is disappeared and reduce pigmentation.
5th, color spot is prevented
EGE has stronger facilitation to the propagation of epidermal cell, use rear youthening of epidermal cell, so that less residual for having pigment and dead cell etc. is accumulated in epidermal tissue, make cutaneous manifestations go out it is tender have no time in vain, eliminate the abnormal skin such as color spot and pigmentation and show.The recurrence of color spot can effectively be contained using EGF in the treatment phase of nti-freckle and convalescence.
Restructuring EGF is protein product, and to keep its bioactivity, the form of freeze-dried powder is typically all made by manufacturer, when in use, uses importing liquid（Solvent）Dissolved and then use it for face.Because EGF is large biological molecule, it is difficult to reach skin corium through skin to play its bioactivity, so can the composition that import liquid be efficiently absorbed to utilize to EGF and play critical effect, in addition, skin care ingredient is suitably added in liquid is imported, it can mutually be cooperateed with EGF effect, reach the effect of multiple skin care.Therefore its composition of this product can effectively help absorbing for EGF, in addition, the skin care moisturizing composition of the importing liquid can also effectively strengthen EGF cosmetology effect.
The beneficial effects of the invention are as follows：EGF freeze-dried powders can be dissolved well, can mutually be cooperateed with EGF effect, reach the effect of multiple skin care, can effectively help absorbing for EGF, itself can also effectively strengthen EGF cosmetology effect.
Embodiment
Embodiment is specifically described below：
Embodiment 1：
A kind of EGF for medical cosmetology imports liquid, it is characterised in that including following components and percentage by weight：
Niacinamide: 1%,
Xanthans:0.1%,
Sodium Polyacrylate:0.2%,
Hyaluronic acid:0.05%,
Artemia extract:0.5%,
Also include dipotassium glycyrrhizinate：0.05%, Aloe Vera Gel：1%, remaining is water.
Embodiment 2：
A kind of EGF for medical cosmetology imports liquid, it is characterised in that including following components and percentage by weight：
Niacinamide: 5%,
Xanthans:0.15%,
Sodium Polyacrylate:0.25%,
Hyaluronic acid:0.3%,
Artemia extract:2%,
Also include dipotassium glycyrrhizinate：0.3%, Aloe Vera Gel：10%, remaining is water.
This product dispel striae of pregnancy experiment：
After person on probation cleans skin of abdomen sooner or later daily, the EGF freeze-dried powders of 20,000 active units of liquid dissolving are imported with 5ml, then the importing liquid is uniformly applied to belly, it is divided to two angels to be finished, after persistently using 60 days, the effectiveness and reliability of product, evaluation criteria are evaluated：Striae of pregnancy disappears or partial disappearance is effective, and striae of pregnancy does not disappear to be invalid；There is pruitus in belly, red and swollen, pimpling, pimple and other allergic symptoms for adverse reaction, otherwise to have no adverse reaction.
Total test total number of persons 200, striae of pregnancy eliminate efficiently individual quantity 196, the invalid people of number 4, and effective percentage reaches 98%；
Total test total number of persons 200, adverse reaction number 2, the invalid people of number 196, adverse reaction effective percentage 1%.
Claims (2)
1. a kind of EGF for medical cosmetology imports liquid, it is characterised in that including following components and percentage by weight：
Niacinamide:
1-5%,
Xanthans:0.1-0.15%,
Sodium Polyacrylate:0.2-0.25%,
Hyaluronic acid:0.05-0.3%,
Artemia extract:0.5-2%, remaining is water.
2. the EGF for medical cosmetology imports liquid as claimed in claim 1, it is characterised in that also including dipotassium glycyrrhizinate：0.05-0.3%, Aloe Vera Gel：1-10%.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610401832.3A CN107468625A (en) | 2016-06-08 | 2016-06-08 | A kind of EGF for medical cosmetology imports liquid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610401832.3A CN107468625A (en) | 2016-06-08 | 2016-06-08 | A kind of EGF for medical cosmetology imports liquid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107468625A true CN107468625A (en) | 2017-12-15 |
Family
ID=60594556
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610401832.3A Pending CN107468625A (en) | 2016-06-08 | 2016-06-08 | A kind of EGF for medical cosmetology imports liquid |
Country Status (1)
| Country | Link |
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| CN (1) | CN107468625A (en) |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101926741A (en) * | 2010-04-02 | 2010-12-29 | 广东雅倩化妆品有限公司 | Skin refinishing essence and skin care product with same |
| CN102058504A (en) * | 2009-11-11 | 2011-05-18 | 日本乐敦制药株式会社 | Anti-saccharification agent |
| CN104721129A (en) * | 2015-04-13 | 2015-06-24 | 上海东晟源日化有限公司 | Microemulsion biotechnology skin care product |
| CN105193694A (en) * | 2015-10-29 | 2015-12-30 | 桂林华诺威基因药业有限公司 | Skin care product with whitening and freckle-removing functions |
-
2016
- 2016-06-08 CN CN201610401832.3A patent/CN107468625A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102058504A (en) * | 2009-11-11 | 2011-05-18 | 日本乐敦制药株式会社 | Anti-saccharification agent |
| CN101926741A (en) * | 2010-04-02 | 2010-12-29 | 广东雅倩化妆品有限公司 | Skin refinishing essence and skin care product with same |
| CN104721129A (en) * | 2015-04-13 | 2015-06-24 | 上海东晟源日化有限公司 | Microemulsion biotechnology skin care product |
| CN105193694A (en) * | 2015-10-29 | 2015-12-30 | 桂林华诺威基因药业有限公司 | Skin care product with whitening and freckle-removing functions |
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171215 |
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| RJ01 | Rejection of invention patent application after publication |