CN107441331A - 一种生精片及其制备工艺 - Google Patents

一种生精片及其制备工艺 Download PDF

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CN107441331A
CN107441331A CN201710661493.7A CN201710661493A CN107441331A CN 107441331 A CN107441331 A CN 107441331A CN 201710661493 A CN201710661493 A CN 201710661493A CN 107441331 A CN107441331 A CN 107441331A
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invigoration
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宋玉
万小青
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GUIZHOU WANSHENG PHARMACEUTICAL LLC
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Abstract

本发明属于药物,具体是一种生精片及其制备工艺。其由以下重量份成分组成:鹿茸46.5~47.1g、枸杞子46.5~47.1g、人参46.5~47.1g、冬虫夏草46.5~47.1g、菟丝子46.5~47.1g、沙苑子46.5~47.1g、淫羊藿46.5~47.1g、黄精46.5~47.1g、何首乌92.89~93.1g、桑葚46.5~47.1g、补骨脂46.5~47.1g、骨碎补46.5~47.1g、仙茅46.5~47.1g、金樱子46.5~47.1g、覆盆子46.5~47.1g、杜仲46.5~47.1g、大血藤46.5~47.1g、马鞭草46.5~47.1g、银杏叶92.9~93.1g。本发明还公开了一种生精片的制作工艺。本发明选药科学,组分合理,经多例临床验证,对治疗肾阳不足所致腰漆酸软,头晕耳鸣,神疲乏力,男子无精,少精,弱精,精液不液化等症状有较好的治疗作用。本发明的制作工艺简单,生产出的产品质量更好。

Description

一种生精片及其制备工艺
技术领域
本发明属于药物,具体是一种生精片及其制备工艺。
背景技术
少精子症,是指精液中精子数量过少,一般认为,精子数每毫升低于2000万,或一次排出精子总数低于5000万者,即可诊断为少精子症。少精子症是导致男性不育的主要原因之一,据统计约占不育症的70%。中医认为,少精症不外乎先天禀赋不足,后天给养缺乏,或纵欲无度,或食辛热太过,嗜酒无度,或精神抑郁,精血暗耗,致使肾精不足,精液匮乏。
男性不育症除了先天性睾丸畸形和发育不良外,外在的潜在危害是男士内裤,往往容易被忽视。阴囊的收缩是为了调节睾丸的温度低于体温2度左右,睾丸只有低于体温2度左右才有利于睾丸酮的分泌达到最佳状态。睾丸酮是促进精子生成的重要物质。现在流行紧身的男士内裤,一般前面设计都是双层的,将阴囊和阴茎包裹在一起,久了导致胯下长期在高温潮湿的环境中,成为病毒细菌滋生的温床。胯下长时间的高温潮湿是引发男性前列腺炎、精索静脉曲张、精囊炎、阴囊湿疹等常见男性疾病的潜在危险。前列腺炎、精索静脉曲张和精囊炎是男性不育症常见疾病。所以专家建议多穿透风透气、散热隔离好的阴囊袋内裤,长期保持胯下干爽透气散热。
发明内容
针对现有技术中的不足之处,本发明旨在提供了一种补肾益精、滋阴补阳及生产工艺简单的生精片及其制备工艺。
为解决上述技术问题,本发明的一种生精片及其制备工艺,由以下重量份成分组成:鹿茸46.5~47.1g、枸杞子46.5~47.1g、人参 46.5~47.1g、冬虫夏草46.5~47.1g、菟丝子46.5~47.1g、沙苑子46.5~47.1g、淫羊藿46.5~47.1g、黄精46.5~47.1g、何首乌92.89~93.1g、桑葚46.5~47.1g、补骨脂46.5~47.1g、骨碎补46.5~47.1g、仙茅 46.5~47.1g、金樱子46.5~47.1g、覆盆子46.5~47.1g、杜仲46.5~47.1g、大血藤46.5~47.1g、马鞭草46.5~47.1g、银杏叶92.9~93.1g。
优选的,由以下重量份成分组成:鹿茸46.9~47.1g、枸杞子 46.9~47.1g、人参46.9~47.1g、冬虫夏草46.9~47.1g、菟丝子46.9~47.1g、沙苑子46.9~47.1g、淫羊藿46.9~47.1g、黄精46.9~47.1g、何首乌 92.99~93.1g、桑葚46.9~47.1g、补骨脂46.9~47.1g、骨碎补46.9~47.1g、仙茅46.9~47.1g、金樱子46.9~47.1g、覆盆子46.9~47.1g、杜仲 46.9~47.1g、大血藤46.9~47.1g、马鞭草46.9~47.1g、银杏叶93~93.1g。
优选的,由以下重量份成分组成:鹿茸46.9g、枸杞子46.9g、人参46.9g、冬虫夏草46.9g、菟丝子46.9g、沙苑子46.9g、淫羊藿46.9g、黄精46.9g、何首乌92.99g、桑葚46.9g、补骨脂46.9g、骨碎补46.9g、仙茅46.9g、金樱子46.9g、覆盆子46.9g、杜仲46.9g、大血藤46.9g、马鞭草46.9g、银杏叶93g。
生精片的制作工艺,包括以下步骤:
1)取上述量份的菟丝子、黄精、人参、冬虫夏草、杜仲、骨碎补、鹿茸作为原料,将之混合磨成细粉;
2)将枸杞子、沙苑子、淫羊藿、何首乌、桑葚、补骨脂、仙茅、金樱子、覆盆子、大血藤、马鞭草、银杏叶加水煎煮三次,第一次加入14倍量的水煮1~1.5小时,第二次加入12倍量的水煮0.8~1小时,第三次加入12倍量的水煮0.3~0.5小时,合并煎液、过滤,然后减压浓缩至相对密度为1.25~1.30的清膏;
3)将步骤1)中所得细粉加入到步骤2)中所得的清膏中,经混匀、干燥、粉碎后,加入适量的淀粉,制成颗粒,再干燥压制成片,包薄膜衣即可。
优选的,在所述步骤2)中,浓缩时温度控制在50~60℃。
鹿茸,性味甘、咸,温,具体壮肾阳,补精髓,强筋骨,调冲任,托疮毒的功效;枸杞子,性味甘,平,具有滋补肝肾,益精明目的功效,功能主治虚劳精亏,腰膝酸痛,眩晕耳鸣,内热消渴,血虚萎黄,目昏不明;冬虫夏草,性味甘,温,功能主治补肺益肾,化痰止咳;菟丝子,气味辛,甘,平,无毒,功能与主治补肾益精,养肝明目。用于肝肾不足的腰膝筋骨酸痛,腿脚软弱无力、阳痿遗精、呓语、小便频数、尿有余沥、头晕眼花、视物不清、耳鸣耳聋以及妇女带下、习惯性流产;沙苑子,性味温,甘,功能主治温补肝肾,固精,缩尿,明目,肾虚腰痛、遗精早泄、白浊带下、小便余沥、眩晕目昏;淫羊藿,性味辛、甘,温,功能主治补肾阳,强筋骨,祛风湿,用于阳痿遗精,筋骨痿软,风湿痹痛,麻木拘挛;更年期高血压;黄精,味甘,性平,能滋肾润肺,补脾益气;何首乌,味苦、甘;涩,性微温,具有补肝肾、益精血、强筋骨、乌发、安神、止汁等功效,用于血虚,头昏目眩,体倦乏力,萎黄;肝肾精血亏虚,眩晕耳鸣,腰漆酸软,须发早白;高血脂症,内服可治血虚、眩晕、耳鸣、失眠、须发早白、腰膝酸软、肢体麻木、关节酸痛、梦遗滑精、、崩漏带下、久痢、高血脂、慢性肝炎、皮肤瘙痒,生何首乌可润肠通便、解毒、淋巴结核;桑葚,性味,凉甘、酸、甜,具有生津止渴、促进消化、帮助排便等作用,适量食用能促进胃液分泌,刺激肠蠕动及解除燥热,具有补肝益肾、生津润肠、乌发明目等功效;补骨脂,性味,苦、辛、温,具有补肾壮阳,固精缩尿,肾虚腰痛,小便频数,小儿遗尿,肾漏,温脾止泻,纳气平喘的功效;骨碎补,性味,苦,温,具有补肾强骨,续伤止痛之功效,用于肾虚腰痛,耳鸣耳聋,牙齿松动,跌扑闪挫,筋骨折伤,外治斑秃,白癜风等;仙茅,性味辛,温,有毒,功能主治温肾阳,壮筋骨,治阳萎精冷,小便失禁,崩漏,心腹冷痛,腰脚冷痹,痈疽,瘰疬,阳虚冷泻;金樱子,性味,酸、甘、涩,平,功能主治固精缩尿,涩肠止泻,缩尿止遗,止咳平喘,抗痉挛,降血脂,抗菌消炎;覆盆子,具有固精补肾,明目的作用,功能主治劳倦、虚劳,肝肾气虚恶寒,肾气虚逆咳嗽、痿、消瘅、泄泻、赤白浊;杜仲,性味,甘微辛,温,功能主治:补肝肾,强筋骨,安胎,治腰脊酸疼,足膝痿弱,小便余沥,阴下湿痒,胎漏欲堕,胎动不安,高血压;大血藤,具有败毒消痈,活血通络,祛风杀虫的作用,功能主治急、慢性阑尾炎,风湿痹痛,赤痢,血淋,月经不调,疳积,虫痛,跌扑损伤;马鞭草,性味,苦,凉,功能主治活血通经,去小便血淋肿痛,利小便,平肝泻火,黄疸,痢疾,血瘀经闭,痛经,症瘕,水肿,小便不利,疟疾, 痈疮肿毒,跌打损伤;银杏叶,性味甘、苦、涩,平,功能主治高血压,动脉硬化,大动脉炎,闭塞性脉管炎,心绞痛,心肌梗死,脑栓塞。
临床疗效:
1、样本信息
应用本发明治疗各种症状305例。病例中,其中年龄最小者为25 岁,年龄最大者为60岁。
2、治疗方法
根据患者病情观察用药周期,将上述药材通过本发明的制作工艺制成药片,口服,每日三次,每次4片。
3、治疗效果
数年来使用该发明治疗男性肾阳不足所致的腰漆酸软,头晕耳鸣,神疲乏力,男子无精,少精,弱精,精液不液化等症状效果显著,治疗周期需要服用1-3个月左右,治疗率在86%以上。
4、典型病例
李先生,男,26岁,住男科医院,经医院诊断为精液不液化,以本发明治疗,治疗一个月后获愈,4个月后妻子怀孕。
王先生,35岁,重庆市人,患男子无精,少精,弱精,住都匀市欧亚男科医院,经过在医院治疗3个月后无效,服用本发明2个月后,传来妻子怀孕消息。
白先生,40岁,患少精子症,结婚10多年妻子仍未怀孕,到医院检查后妻子健康,自己患上患少精子症,多年在各大男科医院仍没有治好,服用本发明2个月后,经过3个月的努力,妻子终于怀孕。
龙先生,男,60岁,患少精子症,结婚30多年妻子仍未怀孕,老年膝下无儿无女,多年吃各种药均没有治好,服用本发明3个月后,妻子终于怀孕,老年得子。
本发明选药科学,组分合理,经多例临床验证,对治疗肾阳不足所致腰漆酸软,头晕耳鸣,神疲乏力,男子无精,少精,弱精,精液不液化等症状有较好的治疗作用。本发明的制作工艺简单,生产出的产品质量更好。
具体实施方式
实施例1:鹿茸46.5~47.1g、枸杞子46.5~47.1g、人参46.5~47.1g、冬虫夏草46.5~47.1g、菟丝子46.5~47.1g、沙苑子46.5~47.1g、淫羊藿 46.5~47.1g、黄精46.5~47.1g、何首乌92.89~93.1g、桑葚46.5~47.1g、补骨脂46.5~47.1g、骨碎补46.5~47.1g、仙茅46.5~47.1g、金樱子 46.5~47.1g、覆盆子46.5~47.1g、杜仲46.5~47.1g、大血藤46.5~47.1g、马鞭草46.5~47.1g、银杏叶92.9~93.1g
制作工艺为:取上述量份的菟丝子、黄精、人参、冬虫夏草、杜仲、骨碎补、鹿茸作为原料,将之混合磨成细粉;
2)将枸杞子、沙苑子、淫羊藿、何首乌、桑葚、补骨脂、仙茅、金樱子、覆盆子、大血藤、马鞭草、银杏叶加水煎煮三次,第一次加入14倍量的水煮1~1.5小时,第二次加入12倍量的水煮0.8~1小时,第三次加入12倍量的水煮0.3~0.5小时,合并煎液、过滤,然后减压浓缩至相对密度(温度控制在60℃)为1.25~1.30的清膏;
3)将步骤1)中所得细粉加入到步骤2)中所得的清膏中,经混匀、干燥、粉碎后,加入适量的淀粉,制成颗粒,再干燥压制成片,包薄膜衣即可。
实施例2:鹿茸46.9~47.1g、枸杞子46.9~47.1g、人参46.9~47.1g、冬虫夏草46.9~47.1g、菟丝子46.9~47.1g、沙苑子46.9~47.1g、淫羊藿 46.9~47.1g、黄精46.9~47.1g、何首乌92.99~93.1g桑葚46.9~47.1g、补骨脂46.9~47.1g、骨碎补46.9~47.1g、仙茅46.9~47.1g、金樱子46.9~47.1g、覆盆子46.9~47.1g、杜仲46.9~47.1g、大血藤46.9~47.1g、马鞭草46.9~47.1g、银杏叶93~93.1g。
制作工艺为:取上述量份的菟丝子、黄精、人参、冬虫夏草、杜仲、骨碎补、鹿茸作为原料,将之混合磨成细粉;
2)将枸杞子、沙苑子、淫羊藿、何首乌、桑葚、补骨脂、仙茅、金樱子、覆盆子、大血藤、马鞭草、银杏叶加水煎煮三次,第一次加入14倍量的水煮1~1.5小时,第二次加入12倍量的水煮0.8~1小时,第三次加入12倍量的水煮0.3~0.5小时,合并煎液、过滤,然后减压浓缩至相对密度(温度控制在60℃)为1.25~1.30的清膏;
3)将步骤1)中所得细粉加入到步骤2)中所得的清膏中,经混匀、干燥、粉碎后,加入适量的淀粉,制成颗粒,再干燥压制成片,包薄膜衣即可。
实施例3:鹿茸46.9g、枸杞子46.9g、人参46.9g、冬虫夏草46.9g、菟丝子46.9g、沙苑子46.9g、淫羊藿46.9g、黄精46.9g、何首乌92.99g、桑葚46.9g、补骨脂46.9g、骨碎补46.9g、仙茅46.9g、金樱子46.9g、覆盆子46.9g、杜仲46.9g、大血藤46.9g、马鞭草46.9g、银杏叶93g。
制作工艺为:取上述量份的菟丝子、黄精、人参、冬虫夏草、杜仲、骨碎补、鹿茸作为原料,将之混合磨成细粉;
2)将枸杞子、沙苑子、淫羊藿、何首乌、桑葚、补骨脂、仙茅、金樱子、覆盆子、大血藤、马鞭草、银杏叶加水煎煮三次,第一次加入14倍量的水煮1~1.5小时,第二次加入12倍量的水煮0.8~1小时,第三次加入12倍量的水煮0.3~0.5小时,合并煎液、过滤,然后减压浓缩至相对密度(温度控制在60℃)为1.25~1.30的清膏;
3)将步骤1)中所得细粉加入到步骤2)中所得的清膏中,经混匀、干燥、粉碎后,加入适量的淀粉,制成颗粒,再干燥压制成片,包薄膜衣即可。

Claims (5)

1.一种生精片及其制备工艺,其特征在于,由以下重量份成分组成:鹿茸46.5~47.1g、枸杞子46.5~47.1g、人参46.5~47.1g、冬虫夏草46.5~47.1g、菟丝子46.5~47.1g、沙苑子46.5~47.1g、淫羊藿46.5~47.1g、黄精46.5~47.1g、何首乌92.89~93.1g、桑葚46.5~47.1g、补骨脂46.5~47.1g、骨碎补46.5~47.1g、仙茅46.5~47.1g、金樱子46.5~47.1g、覆盆子46.5~47.1g、杜仲46.5~47.1g、大血藤46.5~47.1g、马鞭草46.5~47.1g、银杏叶92.9~93.1g。
2.根据权利要求1所述的一种生精片及其制备工艺,其特征在于,由以下重量份成分组成:鹿茸46.9~47.1g、枸杞子46.9~47.1g、人参46.9~47.1g、冬虫夏草46.9~47.1g、菟丝子46.9~47.1g、沙苑子46.9~47.1g、淫羊藿46.9~47.1g、黄精46.9~47.1g、何首乌92.99~93.1g、桑葚46.9~47.1g、补骨脂46.9~47.1g、骨碎补46.9~47.1g、仙茅46.9~47.1g、金樱子46.9~47.1g、覆盆子46.9~47.1g、杜仲46.9~47.1g、大血藤46.9~47.1g、马鞭草46.9~47.1g、银杏叶93~93.1g。
3.根据权利要求1或2所述的一种生精片及其制备工艺,其特征在于,由以下重量份成分组成:鹿茸46.9g、枸杞子46.9g、人参46.9g、冬虫夏草46.9g、菟丝子46.9g、沙苑子46.9g、淫羊藿46.9g、黄精46.9g、何首乌92.99g、桑葚46.9g、补骨脂46.9g、骨碎补46.9g、仙茅46.9g、金樱子46.9g、覆盆子46.9g、杜仲46.9g、大血藤46.9g、马鞭草46.9g、银杏叶93g。
4.根据权利要求1~3中任意一项所述的一种生精片及其制备工艺,其特征在于,包括以下步骤:
1)取上述量份的菟丝子、黄精、人参、冬虫夏草、杜仲、骨碎补、鹿茸作为原料,将之混合磨成细粉;
2)将枸杞子、沙苑子、淫羊藿、何首乌、桑葚、补骨脂、仙茅、金樱子、覆盆子、大血藤、马鞭草、银杏叶加水煎煮三次,第一次加入14倍量的水煮1~1.5小时,第二次加入12倍量的水煮0.8~1小时,第三次加入12倍量的水煮0.3~0.5小时,合并煎液、过滤,然后减压浓缩至相对密度为1.25~1.30的清膏;
3)将步骤1)中所得细粉加入到步骤2)中所得的清膏中,经混匀、干燥、粉碎后,加入适量的淀粉,制成颗粒,再干燥压制成片,包薄膜衣即可。
5.根据权利要求4所述的一种生精片及其制备工艺,其特征在于:在所述步骤2)中,浓缩时温度控制在50~60℃。
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RJ01 Rejection of invention patent application after publication

Application publication date: 20171208

RJ01 Rejection of invention patent application after publication